SGTCid	condition	conc	unit	IPI1|YHR085W.score	IPI1|YHR085W.strain.pval	IPI1|YHR085W.strain.significant	IPI1|YHR085W.strain.rank	expt.zyg.pval	expt.zyg.rank	CID	description	SGTC_target_orf	SGTC_target_gene
SGTC_2624	nerol	100	µM	6.28990002627591	3.52225716385966e-13	yes	1	1.58835243586884e-10	1	637566	A natural product oil.		
SGTC_2754	granisetron	64.02	µM	5.42618580401352	2.78850763313194e-10	yes	2	2.87855145734139e-08	2	5284566	A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.		
SGTC_1403	3909-7815	62.9	µM	4.4107390672855	2.16609022717847e-07	yes	3	5.15091990943737e-06	3	6615483			
SGTC_1196	1588-0294	184	µM	3.72395949002009	9.46336321176722e-06	yes	4	9.80612047723743e-05	6	6144269			
SGTC_495	decylubiquinone	155	µM	3.70214263364727	1.05688656537032e-05	yes	5	0.000106893183866852	2	2971	A Co-enzyme Q analog. A free radical scavenger.		
SGTC_1616	st002734	56.1	µM	3.52874571319942	2.49114195680565e-05	yes	6	0.000208767063952802	11	4026101			
SGTC_1602	st001878	87.6	µM	3.43426961451712	3.91360773784645e-05	yes	7	0.000297076450151685	13	595405		YLR310C	CDC25
SGTC_2685	mycophenolic acid	18.85	µM	3.28033089685049	7.98220104084557e-05	yes	8	0.000518427003855677	6	446541	Mycophenolic acid is a potent reversible inhibitor of IMPDH (inosine monophosphate dehydrogenase), leading to a depletion of GMP and inhibition of de novo synthesis of purines. The resulting imbalance of nucleotide pools also results in inhibiting transcription-elongation.		
SGTC_362	0310-0100	9.03	µM	3.25666023988836	8.88406171192437e-05	yes	9	0.000563656404225659	14	790235			
SGTC_2792	7535235	81.82	µM	3.23320822721833	9.87142914360118e-05	yes	10	0.000612041525008935	20	1281891			
SGTC_68	0986-0284	82.829	µM	3.1556379166324	0.000139220487888914	yes	11	0.000800737664012799	21	423278		YIL048W	NEO1
SGTC_2608	thymoquinone	42.66	µM	3.15429504223724	0.000140042654976446	yes	12	0.000804431712704426	11	10281	A benzoquinone with antoxidant properties and demonstrated potential to act as a histone deacetylase inhibitor (HDAC).		
SGTC_1538	2',3',6-trimethoxyflavanone	63.6	µM	3.1524141858844	0.000141201849674075	yes	13	0.000809632045293745	7	4213774			
SGTC_2757	clomiphene	4.22	µM	3.11297713717171	0.000167678592361691	yes	14	0.000926051823839734	29	1548953	Clomifene has both estrogenic and anti-estrogenic properties, but its precise mechanism of action has not been determined.		
SGTC_1354	1498-1681	81	µM	3.10116970178266	0.000176467682254028	yes	15	0.000963788929634747	18	5754243			
SGTC_716	1683-5115	658	µM	3.02373920414503	0.000245671581660339	yes	16	0.00124835782207106	12	723597			
SGTC_1383	3049-0032	20.7	µM	2.96961347431874	0.000308271477242935	yes	17	0.00149087332367147	21	712864			
SGTC_2973	9094665	17.96	µM	2.88735447678546	0.000432334206019492	yes	18	0.00194248135695224	36	25237061		YIL048W	NEO1
SGTC_1445	4239-0156	97.7	µM	2.84070500605858	0.000521856848900438	yes	19	0.0022506965075384	13	4008346			
SGTC_3225	9130819	49.47	µM	2.82009427192147	0.000566632280985778	yes	20	0.00240047714317833	27	4547121			
SGTC_473	2-arachidonoylglycerol	10	µM	2.76946685134124	0.000692114991215856	yes	21	0.0028074058731133	25	5282280	An endocannabinoid.		
SGTC_2644	guaiazulene	100	µM	2.73852469069249	0.000780943540754098	yes	22	0.00308577630413661	6	3515	A coloring agent.		
SGTC_218	alverine citrate	93.75	µM	2.73604804217113	0.000788488989286825	yes	23	0.00310909735265712	22	21718	An antispasmotic used to treat irritable bowel syndrome.		
SGTC_2692	st077426	47.7	µM	2.72914185635726	0.000809885600999233	yes	24	0.00317496909306529	24	25238571			
SGTC_2643	anethole	100	µM	2.72668626135124	0.000817621375208774	yes	25	0.00319869173397596	14	637563	An anti-fungal, anti-helmenthic and channel blocker.		
SGTC_2583	asiatic acid	100	µM	2.68852415080664	0.000946917042043659	yes	26	0.00358843219875772	30	5320556	A kinase inhibitor; arrests cells at G2/M.		
SGTC_1339	1486-1321	22.7	µM	2.6506046747275	0.00109375285664122	no	27	0.00401739127848483	28	3469382			
SGTC_1779	st039427	55	µM	2.63460217542604	0.00116176173897517	no	28	0.00421179733991098	20	1124498			
SGTC_2555	cholic acid	100	µM	2.62225577363573	0.00121685559421097	no	29	0.0043674924237639	11	6708657	Influences liver metabolism.		
SGTC_3014	9081533	49.47	µM	2.61379938805989	0.00125595964268682	no	30	0.00447707976046973	30	21367265			
SGTC_2663	amphotericin b	100	µM	2.59803873241122	0.00133192235114836	no	31	0.00468789588169559	31	16667679	Amphotericin b is a polyene antifungal that binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.		
SGTC_1501	4491-0275	38.4	µM	2.5839960010461	0.00140311815424265	no	32	0.00488314633557078	19	5104718			
SGTC_938	3126-1755	342	µM	2.58203703133694	0.00141332164565137	no	33	0.00491095226168909	10	1777771			
SGTC_1525	8-methoxypsoralen	92.5	µM	2.58035050733089	0.00142216030170301	no	34	0.00493500397874142	52	4114	Related to psoralen; DNA damaging agent.		
SGTC_2565	isoliquiritigenin	100	µM	2.57975508069501	0.00142529282026982	no	35	0.00494352046226871	40	638278	Binds to benzodiazepine receptor 65X better than valium.		
SGTC_2201	6605497	169.863	µM	2.56722875390968	0.00149267092487023	no	36	0.00512574793463547	18	670741			
SGTC_2424	5537928	59.2	µM	2.54244186830371	0.00163463219735614	no	37	0.00550404554097748	34	5382802			
SGTC_2932	9016711	44.54	µM	2.4804218568231	0.00204530602570761	no	38	0.00656135120061111	35	7117328			
SGTC_120	rhodamine 6G	52.259	µM	2.47102689839726	0.00211509991710968	no	39	0.00673628423152346	71	65211	Rhodamine 6G is a noncompetitive inhibitor of F0F1-ATPase		
SGTC_2811	7967822	32.47	µM	2.47087304574146	0.00211626063180004	no	40	0.00673918292454605	27	2232244			
SGTC_1737	st035557	69.7	µM	2.4438359831612	0.00232944010357498	no	41	0.00726601571398899	31	5716916			
SGTC_975	1335-0046	28.5	µM	2.43827900578325	0.00237559356116785	no	42	0.00737868947853395	31	16486740			
SGTC_1541	2',3',6-trimethoxyflavone	64	µM	2.43152855759464	0.00243277191694653	no	43	0.00751763150799006	33	688801			
SGTC_2382	9035899	200	µM	2.40687564685221	0.00265231955135226	no	44	0.00804482371065258	31	6462679			
SGTC_2404	5161160	200	µM	2.37000016425766	0.00301421013167261	no	45	0.00889403867902525	38	2831543			
SGTC_2730	imipramine	71.33	µM	2.35918137821496	0.00312851705933941	no	46	0.0091576507121118	36	3696	A tricyclic antidepressant.		
SGTC_2073	5212005	126	µM	2.33428806894765	0.00340648137520308	no	47	0.00979032152576301	32	691789			
SGTC_2299	7976368	114.88	µM	2.31980836950724	0.00357818985814374	no	48	0.0101756230616928	35	2979718			
SGTC_191	3914-0123	66.505	µM	2.31534441559243	0.00363267111365489	no	49	0.0102970454292862	36	3144412			
SGTC_798	1287-0182	476	µM	2.29668846327597	0.00386850569619045	no	50	0.0108182740221241	31	1649755			
SGTC_1201	1889-3372	45.9	µM	2.29624813008523	0.00387423410458838	no	51	0.0108308490115427	34	5392199			
SGTC_2953	9074162	66.49	µM	2.24541829932467	0.00458884245226267	no	52	0.0123706458718642	32	16451992			
SGTC_1015	4130-4525	82	µM	2.23178653666576	0.00479949862469429	no	53	0.0128145372862453	37	1363237			
SGTC_1217	1183-1422	255	µM	2.22282274587599	0.00494267654570918	no	54	0.0131138773429518	33	2849664			
SGTC_2071	5230951	39.92	µM	2.2063452903772	0.00521582654190539	no	55	0.0136799162638318	40	1799272			
SGTC_1216	1165-0504	9.65	µM	2.19920996454009	0.005338220664256	no	56	0.0139314980668197	34	6304004			
SGTC_660	4031-1742	102	µM	2.18716026819638	0.00555071866953288	no	57	0.0143654131170668	56	6738706			
SGTC_62	0180-0423	3.232	µM	2.18492128904708	0.00559102100248316	no	58	0.0144473091389841	59	30102		YGL099W	LSG1
SGTC_1506	4226-2149	212	µM	2.18426920835266	0.00560280742731767	no	59	0.0144712359983801	50	991114			
SGTC_2938	9059746	27.26	µM	2.17673251995643	0.00574064380028768	no	60	0.014750265217217	48	6471769			
SGTC_2642	cholecalciferol	100	µM	2.17579758755924	0.00575795065564387	no	61	0.0147851995829065	24	9821465	A vitamin D precursor, similar to steriods.		
SGTC_1945	st075991	56.6	µM	2.17576193825054	0.00575861148776699	no	62	0.0147865330500623	54	1084980			
SGTC_1234	0326-0494	15.5	µM	2.15355251736176	0.00618362609375228	no	63	0.0156376406838166	46	1547813			
SGTC_1618	st003135	44.5	µM	2.13756610115371	0.00650652328268168	no	64	0.0162759877434751	42	1270615			
SGTC_1379	2144-0755	36.5	µM	2.12727292771847	0.00672223757252167	no	65	0.0166987063878708	40	5392327			
SGTC_436	n,n-dimethylsphingosine	3.3	µM	2.12254175540844	0.00682349166498199	no	66	0.0168961350740824	38	5282309			
SGTC_2076	5212012	200	µM	2.11851652348326	0.00691069582910165	no	67	0.0170656735200767	28	604802			
SGTC_520	3584-0023	682	µM	2.11486286963633	0.00699070048422468	no	68	0.0172208183033676	57	1340790			
SGTC_1654	st012436	41.8	µM	2.10655026535692	0.00717577588980925	no	69	0.0175782908394893	20	4323132			
SGTC_404	fumagillin	50	µM	2.08480333601782	0.00768055087465764	no	70	0.0185435778933507	38	12015870	A methionine aminopeptidase binder.		
SGTC_375	3970-0961	9.27	µM	2.0812535681187	0.00776584785213087	no	71	0.0187053513520771	46	2898222			
SGTC_23	0213-0011	39.996	µM	2.06929879449559	0.0080592695421867	no	72	0.0192590283539031	47	627608			
SGTC_2780	5215298	71.43	µM	2.06540411815663	0.00815694396074287	no	73	0.0194423896262035	74	2834131			
SGTC_3300	9124615	50.48	µM	2.05197019481218	0.00850187962589415	no	74	0.0200862795539915	37	24824903			
SGTC_998	3996-0085	177	µM	2.04709272548776	0.0086302467837071	no	75	0.0203244905501782	45	715391			
SGTC_934	2950-0684	338	µM	2.04490566891018	0.00868835651811546	no	76	0.020432079466538	42	1121253			
SGTC_1653	st012112	65	µM	2.0254831483453	0.00921964339514941	no	77	0.0214088885646236	28	720429			
SGTC_556	4058-0063	51.5	µM	2.02025276196831	0.00936748937213222	no	78	0.0216785879741177	40	6615692			
SGTC_2574	2',4'-dihydroxychalcone	14.64	µM	2.01742885648269	0.00944817089390601	no	79	0.0218253892066367	60	5357218	A potent inhibitor of glutathione S-transferases.	YPR085C	ASA1
SGTC_1500	4488-1866	171	µM	2.00242819306491	0.0098870207977478	no	80	0.0226193494086902	42	2900003			
SGTC_2946	9065502	71.43	µM	1.99169351263996	0.0102118968072572	no	81	0.0232023479765481	30	16489101			
SGTC_1424	4048-1941	275	µM	1.98630707832873	0.0103783929702661	no	82	0.0234996185839247	48	X1424			
SGTC_1586	deoxycorticosterone acetate	53.7	µM	1.97798886344519	0.0106401601964326	no	83	0.023964981504329	37	5952	Desoxycorticosterone acetate (DOCA) is used as replacement therapy in ADDISON DISEASE.		
SGTC_1432	4049-0298	68.4	µM	1.97380791183971	0.0107738894569916	no	84	0.0242017944378245	40	741646			
SGTC_2270	7924575	90.91	µM	1.96917288331014	0.0109238505731756	no	85	0.0244666208307424	52	1262135			
SGTC_2616	abietic acid	100	µM	1.96564184622869	0.011039309056355	no	86	0.0246699983568159	52	6708678	Abietic acid is an inhibitor of 5α-reductase.		
SGTC_3104	9120930	49.47	µM	1.95868334343687	0.0112699496941425	no	87	0.0250749411503891	60	17014836			
SGTC_1561	5-methoxyflavone	52.9	µM	1.95727125224767	0.0113172615318034	no	88	0.025157792758231	35	94525			
SGTC_1162	k048-0130	20.1	µM	1.93719133786459	0.0120089472038171	no	89	0.0263609793605482	55	6797406			
SGTC_2788	5282734	71.43	µM	1.917620751169	0.012718069202264	no	90	0.0275795584772775	68	743706			
SGTC_3080	9117754	49.47	µM	1.91137164722936	0.0129520034105868	no	91	0.0279784188122721	60	9550191			
SGTC_3009	9080819	71.4286	µM	1.9012876886798	0.0133373415117255	no	92	0.0286321703734953	57	17027216			
SGTC_1132	3456-3614	2.5	µM	1.90040301247344	0.0133716152754863	no	93	0.0286901259467198	56	3125502			
SGTC_365	0121-0052	13.6	µM	1.89681553763566	0.0135113804763254	no	94	0.0289261439577635	52	3101739			
SGTC_380	3970-0968	6	µM	1.89182416314525	0.0137079373490449	no	95	0.0292572063672161	52	2891601			
SGTC_3168	9103419	49.47	µM	1.88419396800964	0.0140131759131862	no	96	0.0297693715885374	31	16649256			
SGTC_2809	7964133	12.99	µM	1.88414130017067	0.0140153030351686	no	97	0.0297729325216953	73	1253665			
SGTC_848	0368-0089	85.6	µM	1.88360929558471	0.0140368049755122	no	98	0.02980892178086	59	762535			
SGTC_2107	5363541	170.161	µM	1.88187069330471	0.0141072721749915	no	99	0.0299267872198227	63	244052			
SGTC_2551	apiole	73.87	µM	1.87491989459412	0.0143920485333096	no	100	0.0304018723316263	35	10659	A possible DNA adduct former.		
SGTC_669	0108-0021	26.2	µM	1.87432193078827	0.014416776917409	no	101	0.030443033279837	67	17201			
SGTC_496	calpeptin	138	µM	1.86313851154272	0.0148860443503226	no	102	0.0312213905772248	50	73364	A calpain inhibitor.		
SGTC_1200	1643-0193	18.4	µM	1.8387402403001	0.0159555848626932	no	103	0.0329767008382195	70	5403974			
SGTC_3179	9107801	49.47	µM	1.8350318897877	0.0161237812135571	no	104	0.0332504822635054	44	4818259			
SGTC_1799	st045822	46.1415	µM	1.83320065328387	0.0162073978379842	no	105	0.0333863683929012	65	3674992			
SGTC_1325	1431-0015	227	µM	1.83281674639931	0.016224974547694	no	106	0.0334149139432563	54	1103340			
SGTC_46	0329-0187a	2.197	µM	1.83169433416871	0.0162764565150878	no	107	0.0334984866367289	75	46494817			
SGTC_61	0978-8327	98.565	µM	1.8294165154188	0.0163813640171752	no	108	0.0336686176776072	66	6150059		YHR072W	ERG7
SGTC_1024	4507-0395	26	µM	1.82322688969419	0.0166693629699783	no	109	0.0341345170229162	59	4201836			
SGTC_652	0437-0092	114	µM	1.82064500128396	0.0167907707822294	no	110	0.0343304187553616	58	3091274			
SGTC_1620	st003704	16.5	µM	1.8183196343717	0.0169007627879173	no	111	0.0345076467753859	66	2834414			
SGTC_1332	1480-0653	17.5	µM	1.81571166650928	0.0170248545037732	no	112	0.0347073067479207	63	5749438			
SGTC_432	NS 1619	61.3	µM	1.81464635652737	0.0170757674324107	no	113	0.034789136856547	59	4552	A K+/calcium channel activator.		
SGTC_2196	6573537	42.6665	µM	1.81343788376114	0.0171336798334438	no	114	0.0348821554929089	56	2903087			
SGTC_1099	5-nonyloxytryptamine	2.85	µM	1.80969774337943	0.0173139794923079	no	115	0.0351713363368792	67	23581825	A 5-HT1D beta serotonin receptor agonist.		
SGTC_3056	9094900	49.47	µM	1.80518989392514	0.017533439299892	no	116	0.0355224859169396	62	25236784			
SGTC_569	4130-2812	160	µM	1.7970039465118	0.0179380373864771	no	117	0.0361674966177609	59	743552			
SGTC_448	monastrol	171	µM	1.794292302207	0.0180738066851997	no	118	0.0363832630605814	52	2987927	Monastrol is a cell-permeable small molecule inhibitor discovered by Thomas U. Mayer in the lab of Tim Mitchison. Monastrol was shown to inhibit the kinesin Eg5, a motor protein important for spindle bipolarity		
SGTC_1376	2910-0861	41.3	µM	1.78926510169594	0.0183278317274396	no	119	0.0367860657694113	61	1112859			
SGTC_188	3229-0966	278.469	µM	1.78894037694966	0.0183443441717647	no	120	0.0368122091247296	109	5722370			
SGTC_1642	st009582	77.7	µM	1.78754765891292	0.0184153085165637	no	121	0.0369245082249555	80	6739311			
SGTC_595	3909-8003	73.7	µM	1.78620884132735	0.0184837467123559	no	122	0.0370327250436108	68	699517			
SGTC_3073	9114972	49.47	µM	1.78311014777664	0.0186429781410913	no	123	0.0372841874376344	56	41905075			
SGTC_2183	6420625	130.508	µM	1.77879045431827	0.0188669000467721	no	124	0.0376370613794938	88	2897619			
SGTC_959	1222-0044	107	µM	1.7709097583698	0.0192813123140644	no	125	0.0382878546779548	68	6083612			
SGTC_1380	2291-0730	164	µM	1.76885097456389	0.0193908408547623	no	126	0.0384593737194485	61	2999191			
SGTC_538	2922-0838	53.3	µM	1.76627456185146	0.0195286518543859	no	127	0.0386748985817921	71	777039			
SGTC_2967	9089538	49.85	µM	1.76154241859729	0.0197839393373589	no	128	0.0390733200275587	83	728216			
SGTC_2029	5175081	200	µM	1.75012286040338	0.0204116853643079	no	129	0.0400485579371057	69	1380876			
SGTC_790	1575-0012	79.1	µM	1.74038059702401	0.0209604948887496	no	130	0.0408961051183068	68	378741		YLR208W	SEC13
SGTC_2144	5628481	200	µM	1.73821145356207	0.0210843743632596	no	131	0.0410867808380282	49	2818399			
SGTC_2397	5161689	200	µM	1.73735259236439	0.021133594711999	no	132	0.0411624768647719	65	2259942			
SGTC_190	3970-0790	3.722	µM	1.73314459869866	0.0213761570759873	no	133	0.0415349855507286	62	2832352			
SGTC_482	fipronil	114	µM	1.72937562108187	0.0215954074203385	no	134	0.0418709451523192	41	3352	A inhibitor of GABA receptors and glutamate-gated chloride (GluCl) channels.		
SGTC_2075	5212009	200	µM	1.72888774454123	0.0216239267875807	no	135	0.0419145939475676	56	780898			
SGTC_2586	curcumin	80	µM	1.7245119328382	0.0218811454402945	no	136	0.042307733323411	77	6610332	A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties.	YMR203W	TOM40
SGTC_1434	4073-0095	163	µM	1.72196738582496	0.0220319034718821	no	137	0.0425377133487198	68	24133745			
SGTC_2113	5491891	107.031	µM	1.72071738630585	0.0221062834013973	no	138	0.0426510599321975	85	789979			
SGTC_3210	9128157	49.47	µM	1.71876500679326	0.0222228817067311	no	139	0.042828584863421	81	17590849			
SGTC_1847	st056231	15	µM	1.70258145752405	0.0232095057267435	no	140	0.044323211275885	77	5393180			
SGTC_1895	st058434	18.3	µM	1.7002090938411	0.0233571895547443	no	141	0.0445458011705024	87	5393175			
SGTC_2829	7992743	58.44	µM	1.69750041959958	0.023526775444258	no	142	0.0448010459196873	60	16462845			
SGTC_1465	k213-0056	144	µM	1.68371038654442	0.0244062887434523	no	143	0.0461188265278402	95	24048857		YMR208W	ERG12
SGTC_2618	avocadyne	43.43	µM	1.68235906104102	0.0244939408194309	no	144	0.046249617433706	65	3015189			
SGTC_1663	st014140	55.4	µM	1.67608528956044	0.0249043496034066	no	145	0.0468607438626331	64	4207120			
SGTC_2807	7945238	51.95	µM	1.67536440520285	0.0249518746541509	no	146	0.0469313779856511	75	17148797			
SGTC_1328	1441-0025	69.2	µM	1.67144341294111	0.0252117037034026	no	147	0.0473170635075637	55	4562601			
SGTC_2208	7283366	200	µM	1.66671584162064	0.0255279927319385	no	148	0.0477854606895508	66	898663			
SGTC_1807	st050092	58.9	µM	1.66603001080647	0.0255741517283812	no	149	0.047853718584736	77	5008496			
SGTC_1492	4158-0558	28.5	µM	1.66532512012408	0.0256216663286167	no	150	0.047923954750334	57	3967268			
SGTC_890	0929-0006	47.2	µM	1.66372791356374	0.0257296028188836	no	151	0.0480834076972357	74	1378169			
SGTC_2130	NSC 7	2.4545	µM	1.66064863934027	0.0259387691979739	no	152	0.0483920171086363	73	21448			
SGTC_192	3455-0609	60.9	µM	1.65487435497273	0.0263348354493964	no	153	0.048974993629984	70	3769639			
SGTC_935	2996-0153	430	µM	1.65238451248885	0.0265071703989376	no	154	0.04922809535694	73	23738523			
SGTC_936	3005-4620	401	µM	1.64993028465129	0.0266779614452825	no	155	0.049478597878585	80	777207			
SGTC_1585	2',4'-dihydroxychalcone	10.4	µM	1.64958488842691	0.0267020713740221	no	156	0.0495139339276458	84	5357218	A potent inhibitor of glutathione S-transferases.		
SGTC_2823	7987624	58.44	µM	1.64189915785961	0.0272432892560442	no	157	0.0503054522151444	101	2239440			
SGTC_3226	9131256	49.47	µM	1.64145738734438	0.0272746742098591	no	158	0.0503512528639069	47	17178073			
SGTC_1560	lithocholic acid	53.1	µM	1.63984381616081	0.0273895644285354	no	159	0.0505188225967003	59	9903	A bile acid which acts as a detergent.		
SGTC_377	3970-0964	33.1	µM	1.63410997586757	0.0278010979118957	no	160	0.0511178802736287	82	16481235			
SGTC_1529	apigenin	74	µM	1.63388627442423	0.0278172574366347	no	161	0.0511413661410614	76	5280443	Natural flavone that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase.		
SGTC_875	0709-0210	25.7	µM	1.62974280471525	0.0281179869639231	no	162	0.0515779332559141	86	6251364			
SGTC_1177	0983-0204	23.6	µM	1.62693998519959	0.0283229442454392	no	163	0.0518749223201861	97	766818			
SGTC_1198	1612-1005	86.7	µM	1.62538992014334	0.0284368263081782	no	164	0.0520397511574531	95	6998509			
SGTC_2607	solasodine	47.35	µM	1.62523262384243	0.0284484040066131	no	165	0.0520565007577764	108	6710642	Solasodine is a steroidal glycoalkaloid with teratogenic activity.		
SGTC_609	0986-0026	86.3	µM	1.62475131255767	0.0284838549934919	no	166	0.0521077794985661	81	2848610			
SGTC_2670	beta-carotene	100	µM	1.60976543948707	0.0296061612985093	no	167	0.0537245363808359	40	5280489	A carotenoid that is a precursor of VITAMIN A. It is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC). (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Engewood, CO, 1995.)		
SGTC_519	k048-0011	62.8	µM	1.60874582414728	0.0296838364343045	no	168	0.0538359656919361	72	6836379			
SGTC_133	0724-0033	378.92	µM	1.60833080790199	0.0297155011010846	no	169	0.0538813733779356	91	280309			
SGTC_93	0109-0045	59.227	µM	1.59924276857894	0.0304159515735895	no	170	0.0548833353349028	107	88733			
SGTC_2415	st077333	57.7	µM	1.59450001730969	0.0307868923907638	no	171	0.055412043432701	124	2766255			
SGTC_3060	1327-0027	12.5	µM	1.58897216225203	0.0312239562753285	no	172	0.056033338846302	77	16000455		YPR107C	YTH1
SGTC_1702	st027038	51	µM	1.583866940623	0.0316321507043034	no	173	0.0566120009730776	79	5521182			
SGTC_916	4466-0038	42	nM	1.57889352397037	0.032034037339087	no	174	0.057180240840921	118	5722064		YGL116W	CDC20
SGTC_749	1000-0129	128	µM	1.57624531921657	0.0322497450810828	no	175	0.0574846389761302	76	708470			
SGTC_997	3996-0078	137	µM	1.57532884495421	0.032324674542916	no	176	0.0575902796048584	92	735687			
SGTC_2873	9040596	71.43	µM	1.56971735064637	0.0327866000778722	no	177	0.0582404414215856	112	6463863			
SGTC_3340	9146634	11.102	µM	1.566069954631	0.0330897536165593	no	178	0.058666120529101	71	4907387			
SGTC_2893	9048488	25.97	µM	1.55817656157959	0.0337537240380387	no	179	0.0595956997516502	102	6467338			
SGTC_801	0866-0028	10.1	µM	1.55421729672997	0.0340908723305373	no	180	0.0600662965143811	99	6849771			
SGTC_1524	corynanthine	62.1	µM	1.54614232049613	0.034787075301177	no	181	0.0610350999748201	90	18528820	Corynanthine acts as an α1-adrenergic and α2-adrenergic receptor antagonist.		
SGTC_1398	3558-0053	112	µM	1.54404176434109	0.0349700806316272	no	182	0.0612891076379728	62	4532369			
SGTC_597	k018-0003	82.8	µM	1.54122338820107	0.0352168647285405	no	183	0.0616312135768699	79	6786234			
SGTC_3081	9117243	49.47	µM	1.53861541396943	0.0354464964638676	no	184	0.0619491066305409	129	45595589			
SGTC_1223	0764-0573	147	µM	1.5331167699969	0.035934675228676	no	185	0.062623543208386	77	1609797			
SGTC_142	0335-0849	62.6745	µM	1.52896478777385	0.0363069332480632	no	186	0.063136586711122	110	3889043		YPR107C	YTH1
SGTC_1509	1326-1131	80	µM	1.51822766124304	0.0372842556968098	no	187	0.0644785082770676	75	768313			
SGTC_866	0495-0101	262	µM	1.51232990404257	0.037830165817659	no	188	0.065224978608589	105	635694			
SGTC_3185	9108267	49.47	µM	1.51140279551861	0.0379165715057734	no	189	0.065342928774425	84	4910486			
SGTC_1352	1496-0991	99	µM	1.51132010421378	0.0379242860773399	no	190	0.065353457099027	95	3000039			
SGTC_2641	levomentholum	100	µM	1.5094440919702	0.0380996504471526	no	191	0.0655926662479946	74	16666			
SGTC_2446	5162541	200	µM	1.50878539911275	0.0381613798754451	no	192	0.0656768166067972	89	1549321			
SGTC_2593	nobiletin	86.24	µM	1.50864998178598	0.038174080618682	no	193	0.0656941270202241	94	72344	An anti-infammatory.		
SGTC_485	niflumic acid	177	µM	1.50779973477275	0.0382539037789839	no	194	0.0658028950344929	78	4488	A COX2 inhibitor.		
SGTC_116	0155-0182	31.788	µM	1.4981114131951	0.0391731119472932	no	195	0.0670521531413634	97	771486			
SGTC_121	0557-0495	61.343	µM	1.49266067283623	0.0396981196340927	no	196	0.0677630163457374	111	3104427			
SGTC_3205	9113483	49.47	µM	1.48436158572092	0.0405084495899327	no	197	0.0688565100318794	89	17018033			
SGTC_2212	7123476	200	µM	1.47975148155287	0.0409643539918303	no	198	0.0694697905667221	63	1085715			
SGTC_2815	7968870	71.43	µM	1.47115154291976	0.0418259419349626	no	199	0.0706250692265331	100	2977326		YHR190W	ERG9
SGTC_2751	anetholtrithion	17.25	µM	1.47029507913321	0.0419125446482972	no	200	0.0707409266132255	90	2194	A chloretic substance that stimulates the liver to produce bile.		
SGTC_883	0850-0245	24.6	µM	1.46522839397929	0.042427844764206	no	201	0.0714293076456408	123	6823229		YPR165W	RHO1
SGTC_1333	1482-0047	286	µM	1.46514799283427	0.0424360629677788	no	202	0.0714402725719757	93	3811116			
SGTC_1367	1812-0510	76.9	µM	1.46097851408583	0.0428640139602729	no	203	0.0720106689719955	90	1142582		YDR527W	RBA50
SGTC_1989	st071868	50.2	µM	1.46018991352196	0.0429453460017276	no	204	0.072118943324808	110	16414057			
SGTC_1125	tnp00248	1.32998	µM	1.45646113732327	0.043331602293106	no	205	0.0726325926636126	120	24207736			
SGTC_3158	9100007	49.47	µM	1.45357212969525	0.0436327932633984	no	206	0.0730324842571456	77	19297233			
SGTC_739	1486-1183	203	µM	1.44965845338077	0.0440435022329385	no	207	0.0735768934414865	87	4346692			
SGTC_3133	9127736	49.47	µM	1.44660289436931	0.0443663209182791	no	208	0.0740040875542694	92	27243420			
SGTC_2965	9082772	38.63	µM	1.44363463422159	0.0446817396567201	no	209	0.0744208885986626	64	16459634			
SGTC_2522	biochanin a	4.94	µM	1.44168978237008	0.044889384650792	no	210	0.0746949536790511	93	5280373	A possible chelator.		
SGTC_2150	5556613	200	µM	1.44027494941747	0.0450409289766943	no	211	0.0748948128984288	103	743190			
SGTC_2669	eugenol	100	µM	1.43699710367871	0.0453936048560688	no	212	0.0753594082596641	65	3314	Eugenol is a member of the phenylpropanoids class of chemical compounds; antifungal activity of unknown mechanism.		
SGTC_3237	9133362	49.47	µM	1.43684173610008	0.0454103764218182	no	213	0.0753814841602581	103	43845137			
SGTC_3287	9117173	37.0625	µM	1.43678392440183	0.0454166183311442	no	214	0.0753896997789359	56	2789709			
SGTC_1340	1486-1359	257	µM	1.43501234772598	0.0456082296529416	no	215	0.0756417895058823	112	4309068			
SGTC_1276	0871-0068	94.2	µM	1.42496415928689	0.0467073572974188	no	216	0.077083780831447	124	3414906			
SGTC_1666	st014829	29	µM	1.42460411009552	0.0467471324906003	no	217	0.0771358356424874	92	3858230			
SGTC_718	1130-0073	349	µM	1.42347992824776	0.0468714975075081	no	218	0.0772985383228537	101	6740020			
SGTC_222	nsc-310342	10.666	µM	1.41488990808273	0.0478305697177529	no	219	0.0785503886920595	88	432556			
SGTC_2377	9073351	62.6	µM	1.40843597659332	0.0485614347685829	no	220	0.0795010062323197	124	7337946		YHR072W	ERG7
SGTC_3170	9103054	49.47	µM	1.40829194493541	0.0485778466949673	no	221	0.0795223199324954	104	16432970			
SGTC_1923	st058458	19.1	µM	1.40693804061211	0.0487323364275829	no	222	0.079722881114334	126	3534982			
SGTC_1605	st000082	49.1	µM	1.39660421361296	0.0499244720798438	no	223	0.0812663112536774	117	1114022			
SGTC_2215	7188065	200	µM	1.38495994694906	0.0512955301743103	no	224	0.0830323574747075	97	940217			
SGTC_1855	st056195	39.6	µM	1.38181170188192	0.0516713200889272	no	225	0.0835147625322978	106	4028379			
SGTC_783	0848-0141	92.7	µM	1.38093432025106	0.0517764376856094	no	226	0.0836495781231205	136	6755076		YHR007C | YLR033W	ERG11 | RSC58
SGTC_2494	18-aminoabieta-8,11,13-triene sulfate	3.66	µM	1.37587796312304	0.052385547427417	no	227	0.0844297094299931	153	16725076			
SGTC_2977	9011197	71.43	µM	1.37254265655488	0.0527904367832357	no	228	0.0849472845993464	118	2704722			
SGTC_1793	st048256	72.231	µM	1.36889282549749	0.0532363485747021	no	229	0.0855163893718836	102	672022			
SGTC_1088	bifonazole	369	nM	1.36547681593107	0.0536563936509054	no	230	0.0860516175075414	99	2378	Bifonazole, an imidazole, has a dual mechanism; topical antifungal that inhibits lanosterol 14α-demethylase as will as Hmg-CoA reductase.		
SGTC_198	3454-2873	16.191	µM	1.36466927417446	0.0537560746040495	no	231	0.0861785104864986	136	710957			
SGTC_501	nsc-95397	161	µM	1.36165290336007	0.0541297055051936	no	232	0.0866537255115005	129	262093			
SGTC_3253	9135987	49.47	µM	1.36042685380661	0.0542821596735561	no	233	0.0868474426951406	127	4182430			
SGTC_1721	st082152	9.2685	µM	1.35635130633338	0.0547913798284207	no	234	0.0874937092040789	114	5296051			
SGTC_2162	5663267	200	µM	1.35572390368481	0.0548701051008891	no	235	0.0875935154738506	123	6456493			
SGTC_522	1273-0010	11.6	µM	1.34639941089837	0.0560506926843549	no	236	0.0890868704149687	129	5705015			
SGTC_1309	pyrazolanthrone	13.4	µM	1.34223792497919	0.0565840088776935	no	237	0.0897594316683036	133	8515	1,9-Pyrazoloanthrone is derivative of anthrone used in biochemical studies to inhihibit mitogen-activated protein kinase c.	YJR013W	GPI14
SGTC_1023	4482-3888	16	µM	1.34164808850373	0.0566599219546703	no	238	0.0898550630761421	134	3303168			
SGTC_2501	sodium tetradecyl sulfate	13.37	µM	1.33774444659827	0.0571643525784522	no	239	0.0904898784108247	111	23665772	A membrane-active detergent.		
SGTC_2386	9075165	157.42	µM	1.33743795534917	0.0572041067194286	no	240	0.0905398610417376	123	16452277			
SGTC_1399	3562-5772	25	µM	1.33609907870831	0.0573780239372617	no	241	0.0907584455499751	107	23847490			
SGTC_2836	9010338	19.48	µM	1.33579791277975	0.0574172020054677	no	242	0.0908076676961958	101	2994051			
SGTC_405	ebelactone b	50	µM	1.33509436350325	0.0575088073217206	no	243	0.0909227320083178	81	5819825	Inhibitor of esterases, lipases, N-formylmethionine aminopeptidase and carboxypeptidase Y-like kinase (CPY). 		
SGTC_557	1315-0110	16.2	µM	1.33049068401004	0.0581110676412781	no	244	0.0916783268805349	112	6833801			
SGTC_6	0844-0013	19.835	µM	1.32540839574645	0.058781683927417	no	245	0.0925178669310448	159	1584900			
SGTC_2169	5-(ethoxymethyl)quinolin-8-ol	49.5065	µM	1.32486423573855	0.0588538452482469	no	246	0.0926080923942362	138	279621			
SGTC_526	4469-0568	170	µM	1.31941336021666	0.0595805298041196	no	247	0.0935154788251372	118	2901964			
SGTC_3047	9092122	49.47	µM	1.31934729275003	0.0595893805377529	no	248	0.0935265169556139	119	17173831			
SGTC_1239	0337-0584	35.4	µM	1.31560556714785	0.0600923248465814	no	249	0.0941532320229063	156	914301		YML130C	ERO1
SGTC_786	4544-0069	423	µM	1.31538197874512	0.0601224834169724	no	250	0.0941907795082896	142	748821		YLR208W	SEC13
SGTC_193	1273-0060	1.558	µM	1.31384556396777	0.0603300422907643	no	251	0.0944490903749376	120	2847393		YHR072W	ERG7
SGTC_3018	9082602	49.47	µM	1.31197621355394	0.0605833342165079	no	252	0.0947640802036424	132	17332089			
SGTC_2738	aclarubicin	5.55	µM	1.31155428789784	0.0606406189154102	no	253	0.094835282606352	79	451415	Aclarubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.	YOR116C	RPO31
SGTC_2581	avocatin a	64	µM	1.31001818671276	0.0608495328199868	no	254	0.0950948416083291	113	6710728	A skin care supplement.		
SGTC_2099	5377090	177.372	µM	1.30810837060824	0.0611100572795144	no	255	0.0954182773558322	139	2243829			
SGTC_302	1094-0063	18.9	µM	1.30686869445332	0.0612796317396531	no	256	0.0956286549197865	151	5440289			
SGTC_211	3455-0679	143.504	µM	1.30083044738265	0.0621108614758638	no	257	0.0966582487946146	103	748649			
SGTC_2761	levamisole	97.89	µM	1.29587020129954	0.0628002520142687	no	258	0.0975101035346917	95	26879	An alkaline phosphatase inhibitor.		
SGTC_353	1988-1175	58.3	µM	1.2939563617527	0.0630678320011989	no	259	0.0978402472643044	134	2788357			
SGTC_3353	9151644	39.2805	µM	1.29002572196575	0.0636201710978165	no	260	0.0985208637327789	125	4909158			
SGTC_1792	st045773	43.6	µM	1.28454799303453	0.0643961779296458	no	261	0.0994751411539187	55	2919270			
SGTC_428	3448-4153	16.5	µM	1.28058811171248	0.0649617231912318	no	262	0.100169188942897	122	3834874			
SGTC_57	miconazole	162.5	nM	1.28048348673386	0.0649767177100719	no	263	0.10018757436043	142	4189	Miconazole, an imidazole, is a topically used antifungal that acts by inhibiting lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YGL116W	CDC20
SGTC_2799	7812892	81.82	µM	1.28040261320595	0.0649883100874507	no	264	0.100201787698373	152	20205235			
SGTC_1494	4358-1428	177	µM	1.2795492296138	0.0651107315958645	no	265	0.100351857638148	122	1564571			
SGTC_13	0199-0087	65	µM	1.27784378317595	0.0653559212651799	no	266	0.100652256569314	139	4589825			
SGTC_1691	st019933	84.6	µM	1.26920949512173	0.0666082679648968	no	267	0.102183177710847	138	6176082			
SGTC_3291	9121177	71.43	µM	1.26809702436457	0.0667709662615066	no	268	0.102381652022514	105	17015612			
SGTC_3002	9075603	71.4286	µM	1.26692339286293	0.0669429424368296	no	269	0.102591341656793	142	20105405			
SGTC_725	1497-0963	19	µM	1.26628780008377	0.0670362209031652	no	270	0.102705031569963	120	3549977			
SGTC_1052	3253-3998	198	µM	1.26511856502606	0.0672080782764592	no	271	0.102914414388691	107	5450317			
SGTC_845	0330-0138	4.51	µM	1.26362209408278	0.0674285304353009	no	272	0.103182849783075	152	9039800			
SGTC_2672	12a-hydroxy-5-deoxydehydromunduserone	100	µM	1.26022130775065	0.0679315941003866	no	273	0.103794769150151	119	4620898			
SGTC_117	lucigenin	22.078	µM	1.25837007320878	0.0682066548266548	no	274	0.104128974875613	133	65100	An acridine derivative; a dye stuff and potential carcinogen.		
SGTC_2514	salinomycin	42.74	µM	1.24735400232361	0.0698612590556875	no	275	0.10613386227751	134	23682228	A polyether potassium ionophore.		
SGTC_397	arbidol	50	µM	1.24657132209721	0.0699799821367251	no	276	0.106277361233186	122	131410	A RNA synthesis inhibitor.		
SGTC_386	1509-0011	3.07	µM	1.24359248242631	0.0704332560529968	no	277	0.106824792180469	126	3107280			
SGTC_2316	5844804	197.44	µM	1.24177269023759	0.070711272607292	no	278	0.107160220784216	157	776813			
SGTC_1195	1502-0147	41.1	µM	1.23758283386197	0.0713545780721667	no	279	0.107935391370923	125	817940			
SGTC_2774	tamoxifen	10.92	µM	1.23739043978822	0.0713842255469012	no	280	0.107971083158252	135	2733526	Used for treating and preventing breast cancer, tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. 		
SGTC_2736	butenafine	14.65	µM	1.23405453313272	0.0718997853765444	no	281	0.108591292123209	131	2484	Butenafine inhibits squalene epoxidase, an enzyme in the ergosterol biosynthetic pathway. Because ergosterol is part of the fungal cell membrane butenafine is thought to change cell membrane permeability, ultimately resulting in fungal cell lysis.	YGR175C	ERG1
SGTC_653	0203-0016	55.2	µM	1.22760137355441	0.0729052105144696	no	282	0.109798322975448	150	295302			
SGTC_2898	9056270	58.44	µM	1.22751457334671	0.0729188072766552	no	283	0.109814623889652	88	19154699			
SGTC_1220	1838-0075	193	µM	1.22294829962838	0.0736368286843938	no	284	0.110674612063753	130	5529645			
SGTC_2547	epiafzelechin trimethyl ether	100	µM	1.22008153105614	0.0740903665757744	no	285	0.111216984562535	101	6708630	An antioxidant.		
SGTC_3186	9110464	49.47	µM	1.21502922806503	0.0748948574872356	no	286	0.112177471982667	118	17018021			
SGTC_183	3914-0051	30.55	µM	1.21498871460753	0.0749013353717633	no	287	0.112185197835915	112	1596232			
SGTC_1264	0783-0040	158	µM	1.2123431335217	0.0753252755030588	no	288	0.112690529578425	124	2855798			
SGTC_2925	9010536	32.5	µM	1.21179491324348	0.0754133531921782	no	289	0.112795447987083	119	2994177			
SGTC_3004	9076122	71.4286	µM	1.21118494719597	0.0755114432547436	no	290	0.112912265248355	137	44782551			
SGTC_2200	6600604	21.907	µM	1.20801511713566	0.0760227570795178	no	291	0.113520723802429	161	2904777			
SGTC_1946	st076057	65.1	µM	1.20755798157443	0.0760967129358968	no	292	0.113608664902779	122	953009			
SGTC_1805	st050013	60.3	µM	1.20461965068636	0.0765733870867501	no	293	0.114175083563556	142	4037144			
SGTC_321	4534-3890	65.3	µM	1.20440030533834	0.0766090615347679	no	294	0.114217447046656	148	699746			
SGTC_1387	3342-1166	1.8	µM	1.19326431627237	0.0784368844249502	no	295	0.116382936459882	123	3418228			
SGTC_1039	k821-0043	94	µM	1.19252157976815	0.0785599608038635	no	296	0.116528397171654	124	15992768			
SGTC_1739	st037196	92.5	µM	1.19171664394181	0.0786935092491899	no	297	0.116686184806414	120	612214			
SGTC_366	0181-0206	4.31	µM	1.19164960081899	0.0787046402589671	no	298	0.116699333773033	132	274874			
SGTC_2256	7954252	200	µM	1.18970899175202	0.0790273522916106	no	299	0.117080395011795	135	2972920			
SGTC_1938	st074717	56.4	µM	1.18690058862975	0.0794961466736234	no	300	0.117633417563816	140	17250979			
SGTC_671	0560-0003	407	µM	1.18672576997748	0.0795253978114706	no	301	0.117667903371569	121	3238678			
SGTC_434	1-hexadecyl-2-methylglycero-3 PC	8	µM	1.18492419907288	0.0798273162240776	no	302	0.118023709273482	151	1377			
SGTC_3034	9090421	49.47	µM	1.18475862679732	0.0798551072910357	no	303	0.118056447542179	121	17173761			
SGTC_1583	clindamycin	39.6	µM	1.18413885780743	0.0799591995789497	no	304	0.118179050220997	147	32603	Cindamycin is an antibiotic that acts by inhibiting  bacterial protein synthesis.		
SGTC_858	0438-0351	2.77	µM	1.18184029167652	0.0803461474730118	no	305	0.118634538586413	149	2799119			
SGTC_2891	9063876	19.48	µM	1.18165811441269	0.0803768761830506	no	306	0.118670692169758	116	6472478			
SGTC_2662	daunorubicin	22.37	µM	1.18086196893426	0.0805112700548609	no	307	0.118828780790285	157	30323	Daunorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.	YIL143C	SSL2
SGTC_127	0180-0333	59.125	µM	1.17974969340088	0.080699312622801	no	308	0.119049891557584	111	771601			
SGTC_2871	9038510	12.99	µM	1.17466347385502	0.0815634226166077	no	309	0.120064689016961	183	4945164			
SGTC_161	4065-0411	162.148	µM	1.17193187494132	0.0820303708982345	no	310	0.120612204240538	160	1906281		YLR208W	SEC13
SGTC_2605	digitonin	300	nM	1.16943998144378	0.082458097345309	no	311	0.121113204657163	172	2735010	Digitonin is a glycoside obtained from Digitalis purpurea. As a detergent, it effectively water-solubilizes lipids and has several membrane-related applications in biochemistry, including solubilizing membrane proteins, precipitating cholesterol, and permeabilizing cell membranes.		
SGTC_1763	st044482	94.5	µM	1.16476167705755	0.0832656470060412	no	312	0.122057737667915	162	88505			
SGTC_1556	plumbagin	1.48	µM	1.16458726945056	0.0832958670861928	no	313	0.122093049683171	156	10205	Like menadione, plumbagin is a naphthoquinone, and undergoes one electron reduction to semiquinone. Under aerobic conditions the semiquinone radical participates in redox cylcing to generate reactive oxygen species (ROS) such as superoxide and hydrogen peroxide.		
SGTC_1258	0671-0043	57.1	µM	1.1641542276084	0.0833709370751755	no	314	0.122180757954257	162	4298767			
SGTC_272	doxorubicin	8.13	µM	1.16377506107171	0.0834367092570534	no	315	0.122257590639723	160	31703	Doxorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.	YIL143C	SSL2
SGTC_1867	st057372	64	µM	1.16363181996833	0.0834615667439876	no	316	0.122286625229395	126	688837			
SGTC_2594	a-mangostin	100	µM	1.16176594914785	0.0837858711090479	no	317	0.122665274481627	154	45934201	Xanthone derivative isolated from mangosteen (Garcinia mangostana). Antioxidant and anti-inflammatory. α-mangostin has been shown to induce apoptosis, reduce cell proliferation and inhibit tumorigenesis.		
SGTC_2568	diosmetin	100	µM	1.15739369042884	0.084549513620772	no	318	0.1235557753572	172	5281612	Diosmetin is a natural flavonoid and antioxidant that impedes human CYP1A enzyme activity. 		
SGTC_1265	0819-1001	68.8	µM	1.15530012675623	0.0849170109812896	no	319	0.123983772038374	158	3106768			
SGTC_1932	st074806	40.9	µM	1.15129739033225	0.0856229696149021	no	320	0.124804955204759	185	17251235			
SGTC_304	1310-0298	97	µM	1.15124738341851	0.08563181699303	no	321	0.124815238375838	178	1550234			
SGTC_2729	fluphenazine	10.66	µM	1.14734562050622	0.086324241092889	no	322	0.125619403160641	168	3372	An atypical antipsychotic.		
SGTC_2284	7945075	39.21	µM	1.14609641677561	0.0865468128345975	no	323	0.125877630033783	164	1245402			
SGTC_884	0851-0618	334	µM	1.14535398036357	0.0866792964789918	no	324	0.126031276699115	157	9642473			
SGTC_3199	9111318	49.47	µM	1.14319011927219	0.0870662900313432	no	325	0.12647983188186	143	8548020			
SGTC_2078	5212016	200	µM	1.13661287194046	0.0882505128632103	no	326	0.12785007833401	148	1899708			
SGTC_275	trichlorophene	5.69	µM	1.13386362160707	0.0887490533959107	no	327	0.128425879363858	143	62616			
SGTC_2691	st077356	60.2	µM	1.13386115453893	0.0887495017063101	no	328	0.128426396871993	160	2839272			
SGTC_2617	dihydrotanshinone i	20.83	µM	1.12524337673091	0.0903258180173554	no	329	0.130242958350602	171	5316743	Tanshinone extracted from a herb, Salvia miltiorrhiza, commonly used in Chinese traditional medicine. A significant decrease in tumor growth was observed using dihydrotanshinone I and irradiation treatment with a mouse xenograft model.	YDR047W	HEM12
SGTC_2088	5278280	127.392	µM	1.12430395324069	0.0904989011550063	no	330	0.130442050933387	150	791502			
SGTC_583	1488-1091	88.9	µM	1.12083510464344	0.0911401491312383	no	331	0.131179029216464	186	4303273			
SGTC_1507	4075-3230	155	µM	1.11859634925145	0.0915557886407425	no	332	0.131656190820984	143	659771			
SGTC_19	0279-0214	38.434	µM	1.11829763890413	0.0916113522060337	no	333	0.131719947502987	161	3566274		YBR002C	RER2
SGTC_2143	5623677	140.463	µM	1.1161785811912	0.0920062388784194	no	334	0.132172850428381	150	5375313			
SGTC_1103	duloxetine	36.1	µM	1.11285367980855	0.0926283728237333	no	335	0.132885638234545	168	60835	A selective serotonin reuptake inhibitor.		
SGTC_2947	9072639	7.68	µM	1.10831853405035	0.0934819691057552	no	336	0.133862136934636	170	16488146			
SGTC_447	ml7	120	µM	1.10583369004114	0.0939521182973429	no	337	0.13439925499901	142	4216	Selective myosin light chain kinase inhibitor.		
SGTC_1318	1280-3875	124	µM	1.10473148265089	0.094161221126562	no	338	0.134637978706261	183	373245			
SGTC_1996	st072960	66.8	µM	1.10380640540638	0.094336984933148	no	339	0.134838562837488	162	1719405			
SGTC_2758	dehydroepiandrosterone	69.35	µM	1.10299349426135	0.0944916369146225	no	340	0.135014995194937	188	5881	A major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. [PubChem]		
SGTC_626	0214-0009	33	µM	1.10258579276911	0.094569270282078	no	341	0.13510354137631	168	3437874			
SGTC_1789	tunicamycin	25	nM	1.10249719638437	0.094586146772927	no	342	0.13512278834631	166	23847177	Tunicamycin inhibits GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-actelyglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first step of glycoprotein synthesis. Tunicamycin is used as a chemical tool in research to induce the unfolded protein response pathway.	YBR243C	ALG7
SGTC_857	0438-0306	1.35	µM	1.10089004615157	0.0948926740918077	no	343	0.135472257367449	151	4686136			
SGTC_3089	9117425	49.47	µM	1.09982872377346	0.0950954980335794	no	344	0.135703377360193	139	9401657			
SGTC_2347	9049783	174.81	µM	1.09769798103142	0.0955036571234657	no	345	0.136168195836956	170	6467988		YPL169C	MEX67
SGTC_1317	1273-0028	910	nM	1.09763029924822	0.0955166431509505	no	346	0.136182978354669	171	5917803		YLR359W | YHR072W	ADE13 | ERG7
SGTC_472	calcifediol	10	µM	1.09134440452352	0.0967283827427606	no	347	0.137560682845257	139	5283731	A vitamin D metabolite.		
SGTC_2131	toluylene red	5.2905	µM	1.08656766717933	0.0976567219891783	no	348	0.138613960384997	146	11105	A phenazine natural dye and potentional inhibitor of the electron transport chain.		
SGTC_1033	k072-0102	21.3	µM	1.08535243792436	0.0978939358076003	no	349	0.138882794599099	166	5965931			
SGTC_1179	1021-1431	9.29	µM	1.08523278877461	0.0979173142443106	no	350	0.138909282687743	188	2840958			
SGTC_548	1436-0017	110	µM	1.07867394734939	0.099205124123901	no	351	0.140366551784691	160	9677137			
SGTC_2289	7946404	165.07	µM	1.07446250164512	0.100038533209224	no	352	0.141307721310881	181	1246120		YPR165W	RHO1
SGTC_559	1550-0661	158	µM	1.07436217218444	0.100058449708208	no	353	0.141330194879922	156	5830875			
SGTC_1590	st077108	57.8	µM	1.07244937520778	0.100438714830141	no	354	0.14175912042448	156	5489485			
SGTC_1980	st071811	45.7	µM	1.06891012392053	0.10114509867061	no	355	0.142555084825971	181	4974850			
SGTC_3345	9148410	3.559	µM	1.06845159274184	0.101236879184908	no	356	0.142658427497097	166	4903596			
SGTC_2476	5806916	10.51	µM	1.06730714807835	0.101466218225731	no	357	0.142916580666305	161	2870194			
SGTC_460	trequinsin	123	µM	1.06645190545296	0.101637850008719	no	358	0.143109704326429	183	5537	A vasodilator.		
SGTC_2665	lovastatin	100	µM	1.06575222012792	0.101778421384017	no	359	0.143267832410571	165	53232	Lovastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YBR252W	DUT1
SGTC_441	propafenone	146	µM	1.06270960307971	0.102391349096718	no	360	0.143956832290344	190	4932	Slows the influx of sodium ions into the cardiac muscle.		
SGTC_1136	pergolide	1.05886	µM	1.06082209795201	0.102772928918622	no	361	0.144385378821448	186	47811	A dopamine receptor agonist.		
SGTC_2046	4110841	106	µM	1.05920514100254	0.103100635407486	no	362	0.144753182119479	186	44119630		YMR134W	ERG29
SGTC_908	3448-7491	47.7	µM	1.05868603763199	0.103206002147218	no	363	0.144871394355999	156	1203031			
SGTC_1762	st045503	25.4615	µM	1.05748768199395	0.10344954094669	no	364	0.145144536727591	160	4645554			
SGTC_2882	9058044	58.44	µM	1.05423868327849	0.104111924735313	no	365	0.145886826820377	182	18076804			
SGTC_2968	9090663	33.37	µM	1.05065275118139	0.1048465638578	no	366	0.14670905195918	215	25236811			
SGTC_3336	9143619	71.43	µM	1.05009212398848	0.104961756302543	no	367	0.146837879740472	153	45595730			
SGTC_2659	sanguinarine	24.21	µM	1.04966515863412	0.105049546596894	no	368	0.146936043957422	168	13394149	Na+/K+-and Mg2++-ATPase inhibitor. Antimicrobial, anti-inflammatory and antioxidant properties. Induces apoptosis.		
SGTC_310	1273-0058	1.06	µM	1.04846454608489	0.105296694838733	no	369	0.147212314359515	144	2734232			
SGTC_877	0771-0151	33.1	µM	1.04646126931836	0.10571000902255	no	370	0.14767405886222	169	6166523			
SGTC_1446	4239-0190	62	µM	1.04633486351351	0.105736128234148	no	371	0.147703227217995	169	1340085			
SGTC_1659	st012954	42.1	µM	1.04443063030567	0.106130164304928	no	372	0.148143099153118	165	24207262			
SGTC_2585	alliin	100	µM	1.04387212544891	0.106245934631111	no	373	0.148272278113476	158	87310	A garlic compound which reacts with lipids.		
SGTC_961	1252-1571	372	µM	1.04303668709211	0.106419279664488	no	374	0.148465650827179	179	6813498			
SGTC_3157	9099274	49.47	µM	1.04182761462659	0.106670511497613	no	375	0.148745804382503	168	17217662			
SGTC_1519	esterone	74	µM	1.04131723459446	0.106776691188976	no	376	0.148864170264145	170	698	A steroid.		
SGTC_1808	st050063	61.5	µM	1.04067078478281	0.106911288348225	no	377	0.149014183385878	168	4011993			
SGTC_3323	9138564	53.9225	µM	1.03879086443257	0.107303401559238	no	378	0.149451005509708	173	43912313		YNL103W	MET4
SGTC_782	0083-0095	30.5	µM	1.03782429916032	0.107505410553105	no	379	0.149675930952889	167	3591729	An indicator and reagent.		
SGTC_1701	st028638	40.4	µM	1.03620515696218	0.107844419846323	no	380	0.150053220711454	156	3490878			
SGTC_1407	3909-7909	12.3	µM	1.03488107206002	0.108122223021335	no	381	0.150362227597323	166	4411780			
SGTC_1098	clofazimine	15.1	µM	1.03362568486786	0.108386088307704	no	382	0.150655593536695	195	2794	Several studies have pointed to inhibition of K+ transport. However, it is not clear whether inhibition results from a specific interaction(s) or is a consequence of membrane disruption. CFZ also is reported to bind to DNA	YEL034W	HYP2
SGTC_1732	st034308	51.822	µM	1.0319893902685	0.108730710284333	no	383	0.151038543885546	174	830119			
SGTC_561	1550-0330	72.9	µM	1.02920587463003	0.109318758922592	no	384	0.151691471173771	177	6812934			
SGTC_2831	7999036	19.48	µM	1.02882966238456	0.109398412875179	no	385	0.151779862703717	179	2988270			
SGTC_1495	4469-0029	237	µM	1.02821269286788	0.109529131653374	no	386	0.151924894525407	166	793680			
SGTC_223	busulfan	5	mM	1.02564113735481	0.110075181161576	no	387	0.152530384672277	154	2478	A DNA alkylator.		
SGTC_919	tnp00227	403.569	nM	1.02542384742263	0.110121410289348	no	388	0.152581620322091	170	1269246	A methoxyflavone.	YNL221C	POP1
SGTC_1069	diphenylcyclopropenone	8.49	µM	1.02338209064961	0.110556480978892	no	389	0.153063611896484	194	65057	A dermal irritant.	YDR527W	RBA50
SGTC_2027	5150920	200	µM	1.02336900586068	0.110559273137716	no	390	0.153066704035579	168	786715			
SGTC_3302	9125395	16.351	µM	1.0228138598862	0.110677782124562	no	391	0.153197931806621	165	17599668			
SGTC_1542	7-hydroxy-3'-methoxyflavone	49.7	µM	1.02161972663533	0.110933006456587	no	392	0.153480458707772	204	5393153			
SGTC_2533	agelasine	13.65	µM	1.01987808802889	0.111306005561352	no	393	0.153893141393855	172	16667745	Agelasines are 7,9-dialkylpurinium salts isolated from marine sponges (Agelas sp.) that have been associated with inhibition of Na/K-ATPase.		
SGTC_2336	9001819	198.65	µM	1.01917936557248	0.111455899950841	no	394	0.154058910461418	219	2989602			
SGTC_1291	0993-0025	5.79	µM	1.01869136242	0.111560675141746	no	395	0.154174757269112	175	4353356			
SGTC_2103	5378138	10	µM	1.01820965074924	0.111664168640688	no	396	0.154289167040738	178	244142			
SGTC_1406	3909-7906	11.9	µM	1.01436210533909	0.112493261594611	no	397	0.155204999700599	176	X1406			
SGTC_1673	st016611	27.3	µM	1.0139719229485	0.112577585461856	no	398	0.155298074959248	208	5226799			
SGTC_2483	5729050	27.16	µM	1.01385801640264	0.112602210769635	no	399	0.155325253508261	177	2865180			
SGTC_1138	3761-0006	1.03	µM	1.01240014509537	0.112917725835656	no	400	0.155673384507683	160	12061087			
SGTC_2108	5365811	200	µM	1.01213088007895	0.112976069618278	no	401	0.155737739648462	176	780283			
SGTC_654	1124-0271	80.9	µM	1.01077613738271	0.113269938900059	no	402	0.156061793331872	190	5403748			
SGTC_1809	st050081	57.6	µM	1.01027631635355	0.113378497107984	no	403	0.156181462371824	196	5036894			
SGTC_1954	st077032	68.9	µM	1.00906080076733	0.113642809604595	no	404	0.156472737939046	189	698907			
SGTC_2523	spermine	47.74	µM	1.00561003267156	0.114395568089211	no	405	0.157301597949164	160	1103	A DNA binding polyamine.		
SGTC_1027	k015-0025	8.67	µM	1.00414595469053	0.114716015659522	no	406	0.157654133875381	180	3598955			
SGTC_2981	9013952	38.96	µM	1.00325381681777	0.11491159371444	no	407	0.157869206427564	177	2996344			
SGTC_670	4204-0025	119	µM	1.00008754582761	0.115607630618547	no	408	0.158634071331387	169	719039			
SGTC_855	0428-0020	25	µM	1.00004141356995	0.115617793896721	no	409	0.158645233267432	173	6812414			
SGTC_3042	9091578	49.47	µM	0.999680228414761	0.115697387601326	no	410	0.158732641664839	172	25236497			
SGTC_2908	7930301	100	µM	0.99508874425233	0.116712597879945	no	411	0.159846552250603	198	2223178			
SGTC_976	1348-1067	47.6	µM	0.992893025020713	0.117200313257726	no	412	0.160381044625777	174	5310671		YGL099W	LSG1
SGTC_3011	9081274	71.4286	µM	0.99171523827366	0.117462518551754	no	413	0.160668227739502	179	6625322			
SGTC_549	1661-1316	519	µM	0.98840304307843	0.11820212312523	no	414	0.161477648884397	207	2857282			
SGTC_305	1682-2595	20.8	µM	0.988352915109986	0.118213341809235	no	415	0.161489919348187	194	226033			
SGTC_862	0452-0056	10.2	µM	0.988137220667224	0.118261623007522	no	416	0.161542724570801	181	1575396		YLR359W | YHR072W	ADE13 | ERG7
SGTC_2176	5809774	33.9695	µM	0.987622590122515	0.118376874589451	no	417	0.16166875928356	161	2870539			
SGTC_160	3453-0671	289.699	µM	0.986543803402659	0.118618726634076	no	418	0.161933165634521	186	5322268			
SGTC_1262	0737-0114	49.6	µM	0.986060206865219	0.118727256887437	no	419	0.162051784625805	201	765919			
SGTC_3113	9123498	49.47	µM	0.984405483986198	0.119099145612887	no	420	0.16245809137438	225	8897275			
SGTC_915	methyl methanesulfonate (MMS)	110	mM	0.983458329811191	0.119312382362608	no	421	0.162690957181008	204	4156	MMS is a DNA alkylating agent; methylates DNA on N7-deoxyguanine and N3-deoxyadenine inducing DNA damage and stalling of replication forks.		
SGTC_800	3448-7362	155	µM	0.979932277816088	0.120108585144786	no	422	0.163559774360054	225	15991913			
SGTC_3215	9129942	49.47	µM	0.975315113654171	0.121156818513434	no	423	0.164701987899626	206	17682944			
SGTC_12	0849-0099	9.267	µM	0.975094209285577	0.121207131163807	no	424	0.164756765386572	190	6071388			
SGTC_2638	epoxomicin	18	µM	0.973814420809316	0.121498901894535	no	425	0.165074345765298	172	9915668	A protesome inhibitor.		
SGTC_2252	omeprazole	400	µM	0.972800232437654	0.121730470564276	no	426	0.165326298579885	165	4594	A proton pump inhibitor.		
SGTC_2461	5755302	26.15	µM	0.969860174811966	0.122403523142777	no	427	0.16605809673014	207	2788904			
SGTC_2368	9071271	200	µM	0.967326750697301	0.122985578440797	no	428	0.166690357471125	194	27209959			
SGTC_2384	9036245	200	µM	0.966998727721181	0.123061083513273	no	429	0.166772334841614	164	6462766			
SGTC_3296	9122258	64.045	µM	0.965003986598527	0.123520937158486	no	430	0.167271407504681	178	4730474			
SGTC_1858	4-chloro-8-(diethylamino)pyrano[3,2-c]chromene-2,5-dione	62.6	µM	0.964825567222185	0.123562127274152	no	431	0.167316093852158	196	756377			
SGTC_3328	9140624	29.0385	µM	0.963168590989024	0.123945118367949	no	432	0.167731462298339	188	4904392			
SGTC_2520	obtusaquinone	4.71	µM	0.962517709051535	0.124095789317671	no	433	0.167894805949347	201	5967872			
SGTC_1841	st054148	70	µM	0.958474075429506	0.125034710556592	no	434	0.168911878989449	197	675442			
SGTC_656	4090-1979	187	µM	0.95837428535069	0.12505794412295	no	435	0.168937028584113	198	22330961			
SGTC_2706	st078239	82.5	µM	0.958252650980445	0.125086267651072	no	436	0.16896768673909	212	15434492			
SGTC_1416	3966-0321	25.3	µM	0.956940578205114	0.125392079044188	no	437	0.169298624147709	197	582530		YLR208W	SEC13
SGTC_3230	9131665	49.47	µM	0.954986887076177	0.125848402088523	no	438	0.169792164129788	181	15943720			
SGTC_645	0845-0943	5.41	µM	0.951503778780093	0.126664821068158	no	439	0.170674350599791	182	1885106			
SGTC_1382	3002-2117	298	µM	0.94938004463604	0.127164417478426	no	440	0.17121367796428	211	1497314			
SGTC_95	0471-0001	561.058	µM	0.947736886363994	0.127551900754436	no	441	0.171631708849888	200	4015405			
SGTC_284	0988-0104	32.6	µM	0.947415366887151	0.127627816174564	no	442	0.171713581855235	210	4666532			
SGTC_625	k213-0058	121	µM	0.946339618589362	0.127882044317794	no	443	0.171987696041577	210	3655420			
SGTC_118	0083-0097	135.343	µM	0.944097768178594	0.128412983880929	no	444	0.172559844863308	236	5207356			
SGTC_1825	st052143	62.6	µM	0.94356285356047	0.128539894020336	no	445	0.172696541040651	193	674173			
SGTC_2388	9080168	200	µM	0.941380795779402	0.129058495640093	no	446	0.173254875694842	218	15943073			
SGTC_605	1315-0399	119	µM	0.939422647402094	0.129525115114204	no	447	0.173756894886617	206	24020461			
SGTC_1240	0356-0016	42.1	µM	0.938965709856203	0.129634169617371	no	448	0.1738741750151	185	4305613			
SGTC_396	dithiazanine	1.25	µM	0.938870224131709	0.129656966645551	no	449	0.173898689269166	170	10578	An antihelmenthic.		
SGTC_1802	st050112	57.9	µM	0.938761588652865	0.129682906528134	no	450	0.173926582160367	191	4662563			
SGTC_2552	juarezic acid	87.02	µM	0.935668574567517	0.130422961990815	no	451	0.174721927723112	180	1549512			
SGTC_1194	1488-0194	225	µM	0.934891244345521	0.130609409679689	no	452	0.17492217489548	199	1391452			
SGTC_2915	7971052	15.16	µM	0.934148716476024	0.130787681822087	no	453	0.175113592618528	163	5741558			
SGTC_1449	4112-4002	201	µM	0.933366470193109	0.130975671732633	no	454	0.175315393095747	179	2059539			
SGTC_182	3448-4371	550.524	µM	0.927013269841944	0.1325093929631	no	455	0.176959822276289	176	3491403			
SGTC_3238	9133470	49.47	µM	0.926710234342694	0.132582856458365	no	456	0.177038501180825	170	3534688			
SGTC_2328	6201408	200	µM	0.921459011904492	0.133860342981908	no	457	0.178405415665005	216	2890418			
SGTC_1604	st002052	72.4	µM	0.921408839024726	0.133872589408554	no	458	0.178418507854941	188	6254834		YHR062C	RPP1
SGTC_985	1493-0307	8.71	µM	0.921066203205973	0.133956242115944	no	459	0.178507931963016	206	3278274			
SGTC_499	genistein	192	µM	0.916612143350679	0.135046945933746	no	460	0.179672959393454	210	6610345	A kinase inhibitor, peroxisome proliferator-activated receptor activator and oxygen scavenger.		
SGTC_2899	9053889	58.44	µM	0.915555746846066	0.135306525857607	no	461	0.179949975439848	190	6470052			
SGTC_2068	5226020	147	µM	0.914929588265715	0.135460548173002	no	462	0.180114297873441	206	1810509			
SGTC_1123	mangostin	811.285	nM	0.914239783491871	0.135630365199573	no	463	0.180295431949876	144	5281650	An antioxidant.		
SGTC_2895	9054447	58.44	µM	0.912109601764667	0.136155696389295	no	464	0.180855512156037	219	2697450			
SGTC_1013	4112-3890	241	µM	0.912076433399824	0.136163887145286	no	465	0.180864241595729	211	705171			
SGTC_1845	st056753	3.01	µM	0.911930732140181	0.136199871311292	no	466	0.18090259121338	205	5375839			
SGTC_1420	4'-methoxyflavone	42	µM	0.911074395396719	0.136411494232107	no	467	0.18112808817625	197	77793	From seeds of Psoralea corylifolia (Fabaceae)	YLR208W	SEC13
SGTC_1670	st016595	4.04	µM	0.908026000778229	0.137166656187072	no	468	0.181932242338535	242	597879			
SGTC_1181	1222-0449	220	µM	0.907503440680271	0.137296393290967	no	469	0.182070315412698	202	658318			
SGTC_2274	7947094	46.08	µM	0.907012249855139	0.137418418665462	no	470	0.182200159676856	202	2971028			
SGTC_173	1273-0061	2.693	µM	0.906807203317989	0.13746937979335	no	471	0.182254380000018	212	2847414		YPL266W	DIM1
SGTC_634	1611-4317	11.2	µM	0.905928463693804	0.137687922983943	no	472	0.182486858738122	218	2843522			
SGTC_2942	9052777	62.25	µM	0.904346140897098	0.138082045425264	no	473	0.182905943774822	242	6469503			
SGTC_3123	9126162	49.47	µM	0.903710019120102	0.138240706228809	no	474	0.183074592515982	202	25239884			
SGTC_755	1995-0008	37.3	µM	0.901602747041254	0.138767187326014	no	475	0.183633965617985	179	689533			
SGTC_303	1348-1668	34.2	µM	0.901274444734333	0.138849333200746	no	476	0.183721208898698	205	5380509			
SGTC_1924	st058459	75.1	µM	0.898852696725822	0.13945631178099	no	477	0.184365563424598	204	688683			
SGTC_1552	6-methylflavone	10.6	µM	0.898705186435023	0.139493341478799	no	478	0.18440485686583	205	689013			
SGTC_762	1165-0429	115	µM	0.89786282504011	0.139704928673972	no	479	0.184629342904315	214	5967793			
SGTC_2916	7875993	68.79	µM	0.897082432357446	0.139901144979581	no	480	0.184837466088184	229	1299250			
SGTC_3139	9095020	49.47	µM	0.896842994518029	0.139961385033762	no	481	0.184901351066441	171	25236292			
SGTC_2707	st078556	66.6	µM	0.896842314794698	0.139961556070125	no	482	0.184901532444566	189	17250899			
SGTC_900	1112-0045	141	µM	0.896232221841672	0.140115128867876	no	483	0.185064374908508	199	56211		YIL048W	NEO1
SGTC_1635	st007035	42.4	µM	0.894740276183495	0.140491164051161	no	484	0.185462971555309	211	3716403			
SGTC_3048	9093155	49.47	µM	0.893196772026548	0.140880914654282	no	485	0.185875903221848	194	25236002			
SGTC_1335	1486-0900	202	µM	0.892797884981059	0.140981756878676	no	486	0.185982709598785	216	X1335			
SGTC_156	3474-0145	5.642	µM	0.891065766623329	0.141420219746995	no	487	0.186446944498243	195	2265471			
SGTC_1343	1487-0095	224	µM	0.888977077592717	0.141950171674478	no	488	0.18700769958975	232	4560101		YGL055W	OLE1
SGTC_1338	1486-1223	76	µM	0.88864696600601	0.142034052010069	no	489	0.187096420783626	205	3444526			
SGTC_1902	st060212	70.5	µM	0.886870407907956	0.142486046047982	no	490	0.187574337658	201	688944			
SGTC_1741	st038134	10.228	µM	0.886824106281038	0.142497839156783	no	491	0.18758680346601	181	1272587			
SGTC_2439	5492030	7.2	µM	0.877682245759595	0.144839225837467	no	492	0.190058091002408	210	5722370			
SGTC_331	k048-0133	24.5	µM	0.876919981698323	0.145035618094715	no	493	0.190265051071538	215	6813582			
SGTC_2768	sulfasalazine	50.2	µM	0.874512477154954	0.145657072234252	no	494	0.19091961416756	212	5384001	An antioxidant and salicylic acid derivative.		
SGTC_2209	5-(5-methyl-2-thenylidene)-Barbituric acid	122.826	µM	0.8743646006088	0.145695302185886	no	495	0.190959864483992	225	616764			
SGTC_1011	4112-3381	17.4	µM	0.872997813811469	0.146048971586411	no	496	0.191332134664785	214	2877139			
SGTC_3352	9151559	45.5865	µM	0.870698554177315	0.146645227668531	no	497	0.191959384070557	193	17159339			
SGTC_1005	4092-0690	4.4	µM	0.86967755579842	0.146910521346859	no	498	0.192238320543717	223	1529343			
SGTC_734	2023-0417	80	µM	0.869199864451923	0.147034753946628	no	499	0.192368910777501	230	3935732			
SGTC_692	k241-0027	77.8	µM	0.869195748988152	0.147035824556202	no	500	0.192370036089786	211	3600480			
SGTC_1677	st019204	53.9	µM	0.868892191225781	0.147114807431498	no	501	0.192453050538047	194	3945625			
SGTC_2506	ethyl hematommate	54.16	µM	0.867782822563509	0.147403696624936	no	502	0.192756617676791	204	3940691	An allergen.		
SGTC_3213	9129884	49.47	µM	0.86593723929799	0.147885144198516	no	503	0.193262290018998	202	17190742			
SGTC_952	1185-0122	232	µM	0.865057840828064	0.148114918149409	no	504	0.193503521404722	205	678600			
SGTC_431	k089-0097	107	µM	0.864850373583444	0.148169161115152	no	505	0.193560459357804	228	5499420			
SGTC_814	3342-0569	96	µM	0.863838490178585	0.148433911716798	no	506	0.193838310202035	220	4346283			
SGTC_1941	st076221	61.8	µM	0.862677998999065	0.148737933516325	no	507	0.194157266047958	207	2828568			
SGTC_1535	tetrahydropapaveroline hydrobromide	54.3	µM	0.862175338978453	0.148869747885345	no	508	0.194295519087034	211	2724278	An inhibitor of dopamine biosynthesis.		
SGTC_36	0335-0881	14.2	µM	0.860827971139236	0.149223458004171	no	509	0.194666398551401	221	23828853			
SGTC_1828	st055811	49	µM	0.854301129513285	0.15094481876422	no	510	0.196469080762554	218	5877589			
SGTC_1703	st026983	48.3	µM	0.852499361189866	0.151422327839213	no	511	0.196968496706831	214	1104023			
SGTC_315	k915-0449	187	µM	0.851711393139128	0.151631472430875	no	512	0.197187147786799	222	20970215		YNL149C	PGA2
SGTC_3332	9141069	11.198	µM	0.850508280179196	0.151951176129116	no	513	0.197521279438887	217	17332883			
SGTC_2944	9067346	25.62	µM	0.848613482395546	0.152455588808657	no	514	0.198048201149615	220	6473075			
SGTC_2057	5236571	38.335	µM	0.84821340066049	0.152562236187036	no	515	0.198159567769978	205	54684039		YBR257W	POP4
SGTC_164	4100-3994	89.624	µM	0.847099892845101	0.152859317799211	no	516	0.198469722425635	242	4615967			
SGTC_503	tyrphostin 8	294	µM	0.846093072872153	0.153128265339438	no	517	0.198750412396455	244	92970	A tyrosine kinase inhibitor.	YOR207C	RET1
SGTC_3285	9112818	20.8695	µM	0.845943127176297	0.153168346511702	no	518	0.198792236020761	246	17017947		YPR165W	RHO1
SGTC_661	1304-0007	33.6	µM	0.845500817701833	0.153286618363345	no	519	0.198915638159451	227	3117130			
SGTC_1824	st053723	68.6	µM	0.845064863074621	0.153403250150012	no	520	0.19903731249518	220	675225			
SGTC_1603	st002045	67.8	µM	0.843630146718038	0.153787497563283	no	521	0.199438056381348	227	5887985			
SGTC_3096	9117468	49.47	µM	0.843436151010304	0.153839502574504	no	522	0.199492280370428	217	41316311			
SGTC_231	b-estradiol	524	µM	0.841004323142823	0.154492397349605	no	523	0.200172756261841	227	450	A steroid.		
SGTC_1726	st035556	14.5795	µM	0.839831427649069	0.15480794898411	no	524	0.200501454821546	187	5919439			
SGTC_619	1652-1634	108	µM	0.837848651619959	0.155342355623483	no	525	0.201057855282698	223	5400454			
SGTC_3203	9113543	49.47	µM	0.83678858893008	0.155628567300666	no	526	0.201355706336955	221	17018012			
SGTC_2930	9013230	14.89	µM	0.83588240853678	0.155873507089171	no	527	0.201610529880395	224	2995857			
SGTC_1270	0831-1170	17.3	µM	0.830846107094894	0.157239444042382	no	528	0.203030286017762	219	6764716			
SGTC_1678	st019265	80.2	µM	0.830271345227501	0.157395828794349	no	529	0.203192692667747	223	5367020			
SGTC_3330	9141424	71.43	µM	0.830054382677293	0.15745488787266	no	530	0.203254018492246	204	27261020			
SGTC_1540	guanosine	70.6	µM	0.828824659167673	0.157789904405725	no	531	0.203601816238493	225	6802	Guanosine is a purine nucleoside		
SGTC_309	k408-0051	1.48	µM	0.828648363621969	0.157837971367146	no	532	0.203651706268701	230	3640463			
SGTC_2902	5787006	60.46	µM	0.827907458343325	0.158040084227597	no	533	0.203861455377977	230	591003			
SGTC_344	k064-0035	6.43	µM	0.827290307416176	0.158208567564421	no	534	0.204036268077938	219	5088750			
SGTC_2518	prenyletin	46.28	µM	0.827247674699214	0.158220210725489	no	535	0.204048347416513	207	3873459	A coumarin with calcium channel inhibitory activity.		
SGTC_2297	7971671	152.32	µM	0.825792957674348	0.158617836549022	no	536	0.204460774819853	229	909016			
SGTC_2351	9026858	72.31	µM	0.825550526132874	0.15868416534261	no	537	0.204529554882831	240	1409300			
SGTC_949	1165-0505	146	µM	0.825214243149998	0.158776201809779	no	538	0.204624984257468	232	6244267			
SGTC_124	0136-0217	7.121	µM	0.824069477614919	0.159089772150546	no	539	0.204950040906723	244	3976905			
SGTC_341	1486-1430	230	µM	0.823374617505098	0.159280303634926	no	540	0.205147496358639	261	2054753		YPL210C	SRP72
SGTC_2531	methyl deoxycholate	70.07	µM	0.823207941522189	0.159326028603718	no	541	0.20519487677122	235	16667744	Haematoxylin.		
SGTC_2095	5432005	200	µM	0.822198742239752	0.159603070324061	no	542	0.205481897249026	241	783734			
SGTC_3127	9126946	49.47	µM	0.821827171163089	0.159705152026784	no	543	0.20558763362569	211	27243249			
SGTC_2711	st079103	59.1	µM	0.819485353148519	0.160349502453037	no	544	0.206254777601145	223	54693780			
SGTC_85	0868-0259	160.055	µM	0.818996215857969	0.160484302599184	no	545	0.206394286297651	221	83173			
SGTC_270	tamoxifen	5.46	µM	0.816607673618853	0.161143618244722	no	546	0.207076334200868	249	5376	Used for treating and preventing breast cancer, tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. 	YIL048W	NEO1
SGTC_1775	st081588	35.1725	µM	0.815890799495324	0.161341843235975	no	547	0.2072812973734	235	1426443		YGL099W	LSG1
SGTC_1271	0832-2808	169	µM	0.81450402717629	0.16172575496679	no	548	0.207678133049881	252	3663794			
SGTC_2793	7325131	81.82	µM	0.81450218302916	0.16172626589346	no	549	0.207678661065573	228	4176441			
SGTC_2595	hexamethylquercetagetin	100	µM	0.814430859997021	0.161746026967369	no	550	0.207699082864722	248	386331			
SGTC_172	1112-0046	2.638	µM	0.811926200526738	0.16244097680448	no	551	0.208416989683298	234	2802135		YIL048W	NEO1
SGTC_2779	methotrexate	400	µM	0.811844935751938	0.162463557255915	no	552	0.20844030697054	234	126941	Methotrexate is an antineoplastic antimetabolite with immunosuppresent properties. Potent inhibitor of dihydrofolate reductase (DHFR), a key enzyme in folic acid biosynthesis.Methotrexate inhibits folate-dependent processes including DNA, RNA and methionine biosyntheis.	YGR267C	FOL2
SGTC_240	5hr heat shock (37°C) + Streptovitacin	300	µM	0.809508074498933	0.163113757741547	no	553	0.209111480122227	257	91467	include heat shock		
SGTC_1372	2752-0194	270	µM	0.808590772149818	0.163369446486335	no	554	0.209375287208815	227	823334			
SGTC_3095	9117207	49.47	µM	0.807900665765192	0.163561978181498	no	555	0.20957388401208	194	17015229			
SGTC_591	4299-0174	154	µM	0.807230057583756	0.163749211197477	no	556	0.209766975785864	239	5509088			
SGTC_2391	6285546	200	µM	0.807093681385564	0.163787304288037	no	557	0.209806256102909	237	846083			
SGTC_2575	plumbagin	510	nM	0.806025677690764	0.164085821801692	no	558	0.210114021769586	228	10205	Like menadione, plumbagin is a naphthoquinone, and undergoes one electron reduction to semiquinone. Under aerobic conditions the semiquinone radical participates in redox cylcing to generate reactive oxygen species (ROS) such as superoxide and hydrogen peroxide.		
SGTC_1650	st011916	45.8	µM	0.805124315208086	0.164338035909104	no	559	0.210373972835604	252	242528			
SGTC_2349	9023730	187.07	µM	0.803288325933179	0.164852548926031	no	560	0.210904051937234	236	4126287			
SGTC_3246	9135460	32.98	µM	0.803104993044892	0.164903982904097	no	561	0.210957026009505	240	41446951			
SGTC_2498	4'-Methoxychalcone	54.63	µM	0.802990798387278	0.164936025427736	no	562	0.210990026519652	221	641818		YHR062C	RPP1
SGTC_417	st075190	100	µM	0.801260611568463	0.165422001591083	no	563	0.211490394239813	251	222757			
SGTC_1920	st075728	45.7	µM	0.800997708265568	0.165495927060425	no	564	0.211566486290094	225	3400306			
SGTC_1878	temozolomide	1	mM	0.799921236887018	0.165798841622252	no	565	0.211878216310744	232	5394	DNA alkylating agent.		
SGTC_2785	7756463	72.73	µM	0.798139278989604	0.166301064369449	no	566	0.212394834827522	287	2201551			
SGTC_751	0833-0568	350	µM	0.79503624659654	0.167177957979115	no	567	0.213296208941192	244	6954252			
SGTC_776	4476-4378	112	µM	0.792193875418415	0.167983801564468	no	568	0.214123819591199	261	2892008			
SGTC_2341	7987486	176.74	µM	0.787956977091975	0.169189641701187	no	569	0.215360935846817	224	1258686			
SGTC_2864	9034755	47.6	µM	0.786937024903017	0.169480752575035	no	570	0.215659366053562	232	4930451			
SGTC_622	1348-1566	26.3	µM	0.786857508422478	0.169503461364045	no	571	0.215682642037928	235	7340407			
SGTC_1164	k060-0068	93.7	µM	0.786790909253048	0.169522482652923	no	572	0.215702138000672	250	5963676			
SGTC_1288	0973-0013	65.5	µM	0.784181701444025	0.170268772342014	no	573	0.21646675031216	220	4315430			
SGTC_2744	captopril	92.04	µM	0.783894463029935	0.170351057138198	no	574	0.216551019491418	205	44093	angiotensin-converting enzyme (ACE) inhibitor 		
SGTC_1437	4092-1038	11.6	µM	0.783307242455469	0.170519356664318	no	575	0.216723355623837	259	3977136			
SGTC_1344	1488-0097	29.1	µM	0.782667880567535	0.170702721104192	no	576	0.216911084228632	265	747966			
SGTC_1831	st055328	12	µM	0.782037865473793	0.170883528358967	no	577	0.217096160353985	238	1103068			
SGTC_2696	st077691	74.316	µM	0.779869997876822	0.171506617865935	no	578	0.217733699804253	253	757133			
SGTC_2886	9058944	51.95	µM	0.779265751566185	0.171680549033512	no	579	0.21791159246503	193	4949929			
SGTC_1490	4089-0339	670	nM	0.778778646054788	0.171820843443115	no	580	0.218055059376318	248	742542			
SGTC_2584	androsterone	48.74	µM	0.778629824847796	0.171863720999394	no	581	0.218098902458948	225	2754130	A steroid.		
SGTC_1906	st060206	94.7	µM	0.778434048694029	0.171920137365048	no	582	0.218156586318956	252	5133468			
SGTC_2536	dehydroabietamide	32.04	µM	0.778138959721715	0.172005194818967	no	583	0.218243548509782	230	3983547			
SGTC_971	1315-0384	26.7	µM	0.777203620063668	0.172274977813464	no	584	0.218519323386492	247	6769120			
SGTC_3176	9106582	49.47	µM	0.776326673691664	0.172528163333906	no	585	0.218778063788064	202	17018027			
SGTC_973	1325-0077	65.9	µM	0.773719267892676	0.173282355175699	no	586	0.219548411595107	238	2835149			
SGTC_137	0438-0332	85.389	µM	0.772809796213551	0.173545912818973	no	587	0.219817477484932	264	2063393		YER012W | YPR107C	PRE1 | YTH1
SGTC_2407	paclitaxel	400	µM	0.770929383620718	0.174091649908694	no	588	0.220374394682684	256	4666	Paclitaxel is a potent anti-neoplastic and anti-mitotic taxane drug, which binds to the N-terminus of β-tubulin and and stabilizes microtubules arresting the cell cycle at the G2/M phase		
SGTC_1426	4048-4480	71.7	µM	0.770138065084389	0.174321633724834	no	589	0.220608999139492	236	14224343			
SGTC_2198	6589944	200	µM	0.769332650183938	0.174555912549492	no	590	0.220847929646576	226	5290268			
SGTC_1046	2001-0062	216	µM	0.765955858414618	0.175540327851943	no	591	0.221851283758202	255	739778			
SGTC_1078	idebenone	36.1	µM	0.765775038724573	0.175593140162388	no	592	0.221905084479318	266	3686	A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.		
SGTC_1563	conessine	56.1	µM	0.765461888268787	0.175684626357305	no	593	0.22199827624938	239	441082	An anti-amoebic, histamine inhibitor.		
SGTC_1157	4092-0394	27.6	µM	0.765384852692429	0.175707136753706	no	594	0.22202120501687	250	3659885			
SGTC_26	0302-0163	425.158	µM	0.762617737639484	0.176516920794047	no	595	0.22284570152247	284	3100915			
SGTC_3235	9132602	49.47	µM	0.761734162617636	0.176775991555725	no	596	0.223109340739468	252	4912240			
SGTC_3175	9106517	49.47	µM	0.761696861495023	0.176786933807287	no	597	0.223120474473807	248	41468073			
SGTC_1087	pterostilbene	9.05	µM	0.759901114085143	0.177314221134122	no	598	0.2236568478194	263	5281727	Similar to reservatol, lowers cholesterol.		
SGTC_1613	st002381	52.1	µM	0.759227060359107	0.177512400362203	no	599	0.223858370609544	249	551167			
SGTC_2440	5628896	157.78	µM	0.756548294208972	0.178301368251974	no	600	0.224660264304864	269	5522048			
SGTC_301	4119-0100	24.5	µM	0.75594937925812	0.178478066430367	no	601	0.224839773226909	265	2801	A tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent.	YIL048W	NEO1
SGTC_2512	diallyl trisulfide	49.23	µM	0.754575873673508	0.178883708846343	no	602	0.225251752148585	286	16315	Antifungal agent Antilipemic agent Antioxidant Antiprotozoal agent Insecticide Platelet aggregation inhibitor Spermatocidal agent		
SGTC_3119	9125183	49.47	µM	0.753732675808555	0.179133020768354	no	603	0.225504878496937	214	22695334			
SGTC_742	0kpi-0133	140	µM	0.753557697497294	0.179184784727404	no	604	0.225557426808314	257	2728852			
SGTC_1150	3909-7983	10.9	µM	0.752687027710844	0.179442495454907	no	605	0.225819003519612	263	23965914			
SGTC_2174	5790901	200	µM	0.752401582827695	0.17952703536451	no	606	0.225904797509518	259	786020			
SGTC_1662	st014054	52	µM	0.751625356638899	0.179757056029357	no	607	0.22613819507396	256	2838777			
SGTC_3297	9117502	71.43	µM	0.749227584760687	0.180468761227653	no	608	0.226860022883294	226	7453720			
SGTC_2620	irigenin	100	µM	0.748566218599835	0.180665378128231	no	609	0.227059349707537	252	5464170	A phytoestrogen derived from Belamcanda chinensis with an antiproliferative effect on prostate cancer cells in vitro.		
SGTC_3346	9158254	43.5805	µM	0.747885197808335	0.180867978443081	no	610	0.227264703321564	274	17639500			
SGTC_2454	5-benzylidenerhodanine	10.36	µM	0.746533058862242	0.181270654936278	no	611	0.227672734551125	261	1273210			
SGTC_1468	k284-1086	134	µM	0.746519380846484	0.181274731211897	no	612	0.227676864234019	252	15996457			
SGTC_1175	0741-0056	27.6	µM	0.745533499197624	0.181568691468543	no	613	0.227974633836087	259	765927			
SGTC_2152	5568786	200	µM	0.74399360381652	0.182028438494368	no	614	0.228440172339651	262	5399883			
SGTC_1061	3448-9325	110	µM	0.74376115054346	0.182097902294313	no	615	0.228510493581866	275	723482			
SGTC_2226	7298446	200	µM	0.742037176696877	0.182613592896871	no	616	0.229032405643069	256	3283010			
SGTC_3200	9114385	49.47	µM	0.741621351666585	0.182738114612504	no	617	0.229158391632589	236	17018030		YLR208W	SEC13
SGTC_846	0335-0850	148	µM	0.740501559254338	0.183073707793854	no	618	0.229497857703555	250	6819598			
SGTC_454	lyso-paf C-16	6.67	µM	0.740272417279443	0.183142427242533	no	619	0.229567357012464	275	162126	Lyso-PAF C-16 is a metabolite of the platelet-activating factor (PAF); natural occuring lipid involved in cellular signaling.		
SGTC_2814	7977482	42.97	µM	0.738851535608127	0.183568907375611	no	620	0.229998576979125	257	6456762			
SGTC_2998	9066762	71.4286	µM	0.738598056350821	0.183645054625693	no	621	0.230075552410504	252	4945196			
SGTC_2664	lyso-paf C-16	73.48	µM	0.738205645845964	0.183762976776939	no	622	0.230194746279075	272	6710742	Lyso-PAF C-16 is a metabolite of the platelet-activating factor (PAF); natural occuring lipid involved in cellular signaling.		
SGTC_1801	st050089	28.441	µM	0.738028300624778	0.183816285751567	no	623	0.23024862584894	253	5008493		YIL048W | YNL267W	NEO1 | PIK1
SGTC_575	k072-0246	11.9	µM	0.736164150413932	0.184377221450212	no	624	0.230815403204163	254	6796779			
SGTC_1796	st049173	110.4	µM	0.735918951416183	0.184451082695789	no	625	0.230890011596589	279	94134			
SGTC_2122	5258151	111.688	µM	0.735300604201352	0.184637429023034	no	626	0.231078220159077	247	2173356			
SGTC_610	4215-0184	155	µM	0.735215910474404	0.184662961602081	no	627	0.23110400535823	249	5605015			
SGTC_414	piperonyl butoxide	100	µM	0.733961080287271	0.185041511860868	no	628	0.231486229364723	246	5794	A potent inhibitor of cytochrome P450.		
SGTC_899	1083-0020	478	µM	0.732640164335413	0.185440518960803	no	629	0.231888963733353	272	767123			
SGTC_3233	9132340	49.47	µM	0.730791882110859	0.185999722493259	no	630	0.232453141387094	291	17682950			
SGTC_2795	7780010	54.55	µM	0.730671602312261	0.186036149716405	no	631	0.23248988254923	253	953673			
SGTC_25	0118-0223	35.662	µM	0.728823935491016	0.186596278749636	no	632	0.233054684105497	267	5333628			
SGTC_702	1488-0190	94	µM	0.727546683483812	0.186984093581815	no	633	0.233445564138562	239	949357			
SGTC_45	0kpi-0036	14.9	µM	0.726674493046378	0.187249204992666	no	634	0.233712691175679	264	2795021			
SGTC_1894	3',6'-dihydroxyflavone	78.7	µM	0.726607056765262	0.187269712631379	no	635	0.233733352038536	260	688662			
SGTC_819	1013-0258	27.7	µM	0.725163542848318	0.187709023862413	no	636	0.234175852864773	252	5753198			
SGTC_2305	7443522	69.23	µM	0.724777480343979	0.187826623850243	no	637	0.234294276654286	259	5415886			
SGTC_2562	3',7'-dimethoxyflavone	64.92	µM	0.723992526355114	0.188065871977522	no	638	0.234535161678381	250	688664			
SGTC_2063	5246145	200	µM	0.720834541389354	0.189030301606156	no	639	0.235505660361093	257	711240			
SGTC_2634	4'-methoxyflavone	100	µM	0.720354063065345	0.189177303352102	no	640	0.235653512912672	235	77793	From seeds of Psoralea corylifolia (Fabaceae)		
SGTC_2820	7989630	71.43	µM	0.71981811290529	0.189341359664784	no	641	0.235818495616934	216	2984098			
SGTC_2861	9024595	19.48	µM	0.719676138770014	0.189384833136822	no	642	0.235862210490434	235	16482810			
SGTC_1971	st069429	63.5	µM	0.719511113453393	0.18943537276176	no	643	0.235913028604599	263	1246522		YGL099W	LSG1
SGTC_1981	st071826	47	µM	0.719435951614136	0.189458394109057	no	644	0.23593617604087	241	11838600			
SGTC_876	0720-0963	56.8	µM	0.718039396651873	0.189886458577281	no	645	0.23636649781775	262	765861			
SGTC_54	0159-0055	9	µM	0.717314949209017	0.190108746335516	no	646	0.236589892573222	283	3319099			
SGTC_3310	9130229	44.1445	µM	0.71730585541546	0.190111537669722	no	647	0.236592697525468	255	7761258			
SGTC_1053	3366-3204	134	µM	0.714673448019807	0.190920612050189	no	648	0.237405424152952	277	3632071		YPR165W	RHO1
SGTC_554	4483-2211	187	µM	0.714496388892738	0.190975107147907	no	649	0.237460144159411	262	747107			
SGTC_991	3996-0057	64.7	µM	0.713253267179371	0.191357982606405	no	650	0.237844524989411	257	715343			
SGTC_1496	4469-0713	57.4	µM	0.712958621740815	0.191448800891072	no	651	0.237935681155931	279	746691			
SGTC_87	0100-0052	35.5	µM	0.712320907579431	0.1916454533423	no	652	0.238133040056479	278	200187		YGR083C | YDR527W	GCD2 | RBA50
SGTC_1999	st074831	12.5	µM	0.712092492090338	0.191715920100325	no	653	0.238203751580974	275	17112523			
SGTC_1916	st067606	49.2	µM	0.710716245509248	0.192140831381889	no	654	0.238630045280257	251	19590279			
SGTC_775	4577-0580	57.3	µM	0.70804482523389	0.192967266014565	no	655	0.239458710713863	271	2006902			
SGTC_763	3453-1109	128	µM	0.707735495227084	0.193063100853493	no	656	0.239554765230847	259	1560353			
SGTC_349	k015-0014	24	µM	0.706767579321161	0.193363162661692	no	657	0.239855462584175	269	2196908			
SGTC_335	4077-0256	27.6	µM	0.706298773265423	0.193508598588989	no	658	0.240001178078754	278	3121989			
SGTC_187	1488-2104	32.728	µM	0.706124244080232	0.193562759156835	no	659	0.240055438013071	262	2852859			
SGTC_1299	1079-1439	3.74	µM	0.702092010809922	0.19481663020067	no	660	0.241310892165375	275	323161			
SGTC_1661	st013063	9.66	µM	0.701792417519949	0.194909989058852	no	661	0.241404314073833	288	721395			
SGTC_2438	5259590	200	µM	0.70108837506456	0.195129488885148	no	662	0.241623932321635	266	1201127			
SGTC_2239	6685329	187.64	µM	0.700960282591989	0.195169440516363	no	663	0.24166390101	251	805680			
SGTC_3343	9148379	18.9835	µM	0.700279113342032	0.195381978518042	no	664	0.241876506498814	262	1955036			
SGTC_2507	purpurin	79.67	µM	0.69902627885218	0.195773254076361	no	665	0.242267804077335	279	6683	Anthraquninome derivative; natural product; red/yellow dye.	YBR257W | YHR062C	POP4 | RPP1
SGTC_1104	tacrolimus	29.8	µM	0.696697001860145	0.19650197872696	no	666	0.242996217744426	270	23581796	Tacrolimus, also known as FK-506, is a potent immunosuppressant, neuroprotective and neuroregenerative, and T cell proliferation blocker. FK-506 disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12).	YLR029C | YDL195W | YDR464W	RPL15A | SEC31 | SPP41
SGTC_379	3970-0972	5.9	µM	0.696247508962875	0.196642793541197	no	667	0.243136919819688	277	2898042		YBL034C	STU1
SGTC_766	1391-0721	126	µM	0.695910729679198	0.196748338062906	no	668	0.243242368686999	288	1020919		YIL115C	NUP159
SGTC_1988	st071872	53.4	µM	0.695330368957485	0.196930299967944	no	669	0.243424143263629	258	16414116			
SGTC_2292	7671323	168.05	µM	0.691529092647424	0.198124640400267	no	670	0.24461655227467	293	937504			
SGTC_1476	4112-3294	3.34	µM	0.691325683597217	0.198188673455053	no	671	0.244680447492907	260	704369			
SGTC_1031	k035-0009	16	µM	0.690325181116127	0.198503812887391	no	672	0.244994857908936	276	5180959			
SGTC_1719	st032227	49.2	µM	0.690011029983855	0.198602826903044	no	673	0.245093625511407	267	3125804			
SGTC_2463	5473429	200	µM	0.689272602638033	0.198835681377107	no	674	0.245325867818526	257	5399405			
SGTC_3195	9113082	49.47	µM	0.688414039829463	0.199106625989204	no	675	0.245596042502786	269	17018038			
SGTC_588	3970-1144	52.9	µM	0.688225557171894	0.199166136967221	no	676	0.2456553760813	253	1888707			
SGTC_1720	st037298	9.481	µM	0.688062175310704	0.199217731359352	no	677	0.245706814258484	287	597396			
SGTC_823	0417-1665	178	µM	0.687223808608822	0.199482605967106	no	678	0.245970851617794	287	3429856			
SGTC_2137	5261020	140	µM	0.686002631062909	0.199868805362585	no	679	0.246355724633641	267	763655			
SGTC_1806	st050005	60.3	µM	0.685991009004311	0.199872483016433	no	680	0.246359389055381	258	5194765			
SGTC_2421	5690543	90.72	µM	0.6849234513728	0.200210471701414	no	681	0.246696113311871	285	3397993			
SGTC_2478	5763493	32.33	µM	0.683986098591891	0.200507520542546	no	682	0.246991972016064	273	1365576		YLR208W	SEC13
SGTC_802	4112-3352	742	µM	0.683241335058264	0.200743726079944	no	683	0.247227178635864	251	704594			
SGTC_2014	4013930	200	µM	0.682787804834319	0.200887647281015	no	684	0.247370468403078	277	64556			
SGTC_942	3253-1115	227	µM	0.681532091078994	0.201286452624149	no	685	0.247767434053315	307	46497897			
SGTC_2330	7979373	200	µM	0.679760791897758	0.201849810322362	no	686	0.248327968201126	266	1863007			
SGTC_3182	9108849	49.47	µM	0.679709396277208	0.201866170664067	no	687	0.248344242620853	260	17133045			
SGTC_2666	tannic acid	100	µM	0.679335318752001	0.201985271576927	no	688	0.24846271137042	281	16134267	A thiamine antagonist.		
SGTC_1135	dihydrocapsaicin	536.708	nM	0.677175496560491	0.202673750026158	no	689	0.249147306314862	292	107982	A Capsaicinoid.		
SGTC_1346	1488-2224	62.4	µM	0.674385879251644	0.203565058360187	no	690	0.250033008908952	273	3722427			
SGTC_968	1309-0633	340	µM	0.673270423410098	0.20392211001231	no	691	0.250387632768283	285	3761976			
SGTC_2184	6075246	200	µM	0.671197671355413	0.204586577468	no	692	0.251047305967525	279	2267320			
SGTC_871	0574-0004	149	µM	0.670712898707756	0.204742167964383	no	693	0.251201722078443	291	9551173			
SGTC_40	0327-0103	19.753	µM	0.67004980442393	0.204955105728536	no	694	0.251413020840605	272	409036			
SGTC_1647	st011722	22.4	µM	0.668367690360578	0.205495868987158	no	695	0.251949457171592	276	2854783			
SGTC_3111	9122088	49.47	µM	0.667404830771622	0.205805788392929	no	696	0.252256790528678	267	16876704			
SGTC_1562	morin hydrate	59.1	µM	0.66733327127265	0.205828832596886	no	697	0.252279639360646	281	18542136	Morin hydrate is a flavonoid with antioxidant properties. Morin not only scavenges oxyradicals, but also moderately inhibits xanthine oxidase.		
SGTC_2283	7944793	200	µM	0.666952525204854	0.20595146945353	no	698	0.252401229308971	272	2970533			
SGTC_1417	3966-0327	90.4	µM	0.666339185638821	0.206149114907131	no	699	0.252597162126684	290	651118			
SGTC_318	1488-0629	67.2	µM	0.666055269686814	0.206240643394327	no	700	0.252687886889845	294	3662576			
SGTC_955	1216-0110	33	µM	0.665962646638914	0.206270508312706	no	701	0.252717488107826	292	3619719			
SGTC_2499	avocadenofuran	51.48	µM	0.665333882014453	0.206473311826668	no	702	0.25291848202252	290	6857792	A insecticide and lysyl oxidase inhibitor.		
SGTC_844	0330-0132	15.3	µM	0.664809793614792	0.206642443008365	no	703	0.253086078900056	281	2828079			
SGTC_528	3492-0019	172	µM	0.66371677027753	0.206995441900508	no	704	0.253435801904273	286	2869262			
SGTC_2466	5983409	37.09	µM	0.662536520014718	0.207377011669586	no	705	0.253813718960143	280	2879657			
SGTC_2413	inermin	26.06	µM	0.662384588982355	0.207426160502913	no	706	0.253862388878996	295	91510	Inermin is a bioactive isoflavanoid.	YFL038C	YPT1
SGTC_1159	4092-0538	61.2	µM	0.66230371576475	0.207452325341287	no	707	0.253888297979874	297	717301			
SGTC_2049	5262831	67.185	µM	0.661142197684454	0.20782832539744	no	708	0.254260562961871	282	763417			
SGTC_2202	7226349	200	µM	0.659401949838286	0.208392421185538	no	709	0.254818845185883	264	844334			
SGTC_1952	st077036	64.1	µM	0.658925562858462	0.20854699780213	no	710	0.25497178485733	287	2937007			
SGTC_1130	3454-2858	15.9	µM	0.655343522790728	0.20971145089056	no	711	0.256123302485204	304	715628		YIL048W	NEO1
SGTC_437	s-farnesyl-l-cysteine methyl ester	6.67	µM	0.654489142763069	0.209989757231707	no	712	0.256398359895343	288	6439225	Stimulates the multidrug resistance transporter ATPase activity (4-5-fold at 10-20 µM) and competes for drug binding.		
SGTC_712	r015-0009	80.6	µM	0.65324838928936	0.210394307333098	no	713	0.256798079519862	292	6813872		YLR060W	FRS1
SGTC_1452	4194-0072	190	µM	0.651411746961647	0.210993987332957	no	714	0.25739036484615	298	1343545			
SGTC_1861	st057647	17.4	µM	0.651311624519064	0.211026706973379	no	715	0.257422672989241	283	688668			
SGTC_3181	9108277	49.47	µM	0.650099281885146	0.211423132012674	no	716	0.257814046535816	302	17097298			
SGTC_2740	felodipine	17.08	µM	0.64983955477194	0.211508117113056	no	717	0.257897932881746	259	3333	L-type calcium channel blocker		
SGTC_3307	9126885	69.2785	µM	0.648690962525826	0.211884186804126	no	718	0.258269073525569	266	24824909			
SGTC_2704	st078022	71.1	µM	0.648541283817895	0.211933223089506	no	719	0.258317459068937	296	54697681			
SGTC_1083	didemethylchlorpromazine sulfoxide	707.394	nM	0.648354752433038	0.211994341981242	no	720	0.258377764282366	297	398788	A metabolite of chlorprazamine and quinoline alkaloid. Quinoline alkaloids readily oxidize, producing quinone and semiquinone derivatives that may lead to the formation of reactive oxygen species	YPL252C | YPL251W	YAH1 | YPL251W
SGTC_2870	9038528	12.99	µM	0.647878044946688	0.212150586832007	no	721	0.258531915968848	287	6463316			
SGTC_593	1203-0218	61.7	µM	0.646046579477243	0.212751490761503	no	722	0.259124595004452	297	3666956			
SGTC_2703	st077852	53.4	µM	0.644907510870231	0.213125719893987	no	723	0.259493562046606	299	6281836			
SGTC_3319	9138450	16.7555	µM	0.643634666963144	0.213544353420629	no	724	0.259906182339412	279	2029690			
SGTC_940	3232-1287	54.8	µM	0.641383972754577	0.214285769789369	no	725	0.260636621698279	295	1585493		YIL048W	NEO1
SGTC_821	1114-0266	29.2	µM	0.637135531716593	0.215689350922931	no	726	0.262018282987219	291	3123235			
SGTC_2044	5102272	200	µM	0.636059279235283	0.216045762756796	no	727	0.262368892698458	289	592666			
SGTC_2554	13-methyl-4,4-bisnor-8,11,13-podocarpatrien-3-one	66.67	µM	0.635175066121278	0.216338833925979	no	728	0.262657121601032	270	6708561			
SGTC_3191	9110352	49.47	µM	0.634974184762282	0.216405447829705	no	729	0.262722625918492	302	17122424			
SGTC_3217	9129673	49.47	µM	0.634877382169286	0.216437552600427	no	730	0.262754194736843	297	17248312			
SGTC_1041	0206-0046	107	µM	0.634055702203877	0.216710175352819	no	731	0.263022235356838	304	50494			
SGTC_2914	7968218	45.32	µM	0.633468022087156	0.21690528174548	no	732	0.26321402845743	266	2977111			
SGTC_154	3389-1638	511.116	µM	0.632870023254825	0.217103918081981	no	733	0.263409262440721	321	5238686			
SGTC_774	k060-0086	136	µM	0.632485607563117	0.217231664319671	no	734	0.263534805066885	308	5911235			
SGTC_2399	5884133	200	µM	0.630326098196856	0.217950103383241	no	735	0.26424062560089	289	722445			
SGTC_2445	5742597	35.57	µM	0.629451705497409	0.218241391034346	no	736	0.264526688301832	289	1774255			
SGTC_3015	9080845	49.47	µM	0.629185724407628	0.218330042158627	no	737	0.264613736821256	283	5296973			
SGTC_1687	st020778	55.3625	µM	0.628369197340949	0.218602319042214	no	738	0.264881055356668	283	4259299			
SGTC_2321	7390090	138.78	µM	0.627819262146815	0.218785809040251	no	739	0.265061173091754	305	649046			
SGTC_573	3702-0553	84.7	µM	0.627808111897447	0.218789530320976	no	740	0.265064825724897	284	1222756			
SGTC_2367	9070478	135.38	µM	0.626706958745748	0.219157208194282	no	741	0.265425670780648	281	572802			
SGTC_1836	st055642	81	µM	0.626692678520201	0.219161978730502	no	742	0.265430352010606	302	8571			
SGTC_2369	9071472	200	µM	0.626629677172049	0.21918302604447	no	743	0.265451005111576	301	17296037			
SGTC_3001	9076041	71.4286	µM	0.625957206059312	0.219407755696246	no	744	0.265671505371428	288	16004211			
SGTC_1972	st070201	17.4	µM	0.624885815301993	0.219766071595796	no	745	0.266023001346808	296	2829099			
SGTC_3219	9131112	49.47	µM	0.623571764730114	0.220206000969387	no	746	0.26645442920884	280	17612988		YMR079W	SEC14
SGTC_2851	9015922	71.43	µM	0.622495734875525	0.220566619465019	no	747	0.266807973721351	303	2996893			
SGTC_3151	9099821	49.47	µM	0.621898811238222	0.220766817090653	no	748	0.267004203424701	309	17174189			
SGTC_400	oxethazaine	37.5	µM	0.621725146078602	0.22082508084761	no	749	0.267061306928248	296	4621	A local anesthetic.		
SGTC_529	4076-0302	30.3	µM	0.621471155881468	0.220910309089354	no	750	0.267144833516788	303	5816522			
SGTC_2983	9022671	12.99	µM	0.621122734624605	0.221027254982596	no	751	0.267259435919775	296	6405161			
SGTC_896	0964-0007	44.5	µM	0.61992915962896	0.221428141077113	no	752	0.267652213495001	300	6756758			
SGTC_620	0109-0052	432	µM	0.619487614568739	0.221576548113754	no	753	0.267797589321449	306	493037			
SGTC_2530	3-alpha-hydroxy-4,4-bisnor-8,11,13-podocarpatriene	92.62	µM	0.616819544165358	0.222474517905346	no	754	0.268676879665082	324	6708760			
SGTC_2273	7815444	169.05	µM	0.616777033472869	0.222488842144556	no	755	0.268690901237553	344	2824616			
SGTC_1530	rhein	70.4	µM	0.61594892364317	0.222767983735631	no	756	0.268964115294291	294	10168	An apoptosis inducer thought to act through induction of endoplasmic reticulum stress and Ca2+-dependent mitochondrial death.		
SGTC_1100	amiodarone	5.07	µM	0.615316495642862	0.222981298688521	no	757	0.269172862926399	275	441325	Amiodarone is a non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ inSaccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.		
SGTC_1357	1503-1303	39.5	µM	0.61508815902554	0.223058344118158	no	758	0.269248250725448	278	292895			
SGTC_1298	1079-1278	263	µM	0.612424846052133	0.22395811910812	no	759	0.27012835365489	299	2840950			
SGTC_2917	7979103	53.79	µM	0.610936367988514	0.224461884302937	no	760	0.270620853560829	298	2980565			
SGTC_1090	efavirenz	20.7	µM	0.609245751378134	0.225034841080985	no	761	0.27118077945384	301	64139	A non-nucleoside reverse transcriptase inhibitor.		
SGTC_288	1315-0019	35.1	µM	0.608790092217799	0.22518940747539	no	762	0.271331790822247	307	6811474			
SGTC_308	4092-1169	104	µM	0.607309888177218	0.225691929571808	no	763	0.271822638689185	319	2268590		YDL196W	YDL196W
SGTC_3032	9089427	49.47	µM	0.607238225004772	0.22571627496222	no	764	0.271846413997074	286	17173707			
SGTC_3137	9097352	49.47	µM	0.607065571022624	0.225774935019658	no	765	0.271903698735366	330	44120435			
SGTC_1222	0366-0074	1.18	µM	0.606159209532208	0.226083017298876	no	766	0.272204518221694	325	286520			
SGTC_319	1348-1596	45.5	µM	0.605156059162479	0.226424276038546	no	767	0.272537654467184	325	5380505			
SGTC_3102	9121669	49.47	µM	0.603241820268132	0.227076281737994	no	768	0.273173915284174	316	41905072			
SGTC_3354	9151612	71.43	µM	0.598884260614008	0.228564443144614	no	769	0.274625033961329	289	27261949			
SGTC_1685	st024049	53.0905	µM	0.598226066946646	0.228789699796934	no	770	0.274844550269901	317	1941139			
SGTC_2352	9027995	87.8	µM	0.598177814799857	0.228806218252939	no	771	0.274860646402075	300	2997347			
SGTC_3194	9111903	49.47	µM	0.594587016142693	0.230037355644107	no	772	0.276059780573824	336	17087251			
SGTC_2892	9047358	58.44	µM	0.592398001378008	0.230789693922432	no	773	0.276792052186665	311	6466771			
SGTC_2011	4012611	177	µM	0.591443043810715	0.231118331485907	no	774	0.277111803451745	303	2049887			
SGTC_2048	5246248	200	µM	0.5908453238237	0.231324162693851	no	775	0.277312031734465	285	677046			
SGTC_680	0417-1641	114	µM	0.590693957809649	0.231376303403588	no	776	0.277362748570129	298	2835990			
SGTC_696	1560-0013	611	µM	0.590629061358259	0.231398660145193	no	777	0.27738449422369	290	1650269			
SGTC_1979	st071809	45.3	µM	0.58939288213753	0.231824752200585	no	778	0.277798875115752	319	4976333			
SGTC_939	1165-0479	45.3	µM	0.588614563326258	0.232093250838702	no	779	0.278059931125486	320	1377347			
SGTC_1356	1502-0781	85.8	µM	0.58779963878948	0.232374562861499	no	780	0.278333393260942	304	567702			
SGTC_409	arachidonic acid	100	µM	0.587174200691429	0.232590592726982	no	781	0.278543358791438	309	231	Arachidonic acid is a polyunsaturated fatty acid present in the phospholipids (especially phosphatidylethanolamine, phosphatidylcholine, and phosphatidylinositides) of cellular membranes.		
SGTC_2770	toltrazuril	17.5	µM	0.584763243080033	0.233424395050637	no	782	0.279353461413005	292	68591	Kills coccidiodes.		
SGTC_1877	wortmannin	25	µM	0.584646975974105	0.233464646577055	no	783	0.279392557078944	322	312145	A covalent inhibitor of PI 3-kinase.		
SGTC_1937	st074714	47.2	µM	0.58351921302727	0.233855276424511	no	784	0.279771913488463	304	17250970			
SGTC_166	k072-0058	166.424	µM	0.583242432288072	0.233951201910126	no	785	0.279865055050668	317	5846229			
SGTC_923	1900-2434	73.3	µM	0.581737659826554	0.234473100749336	no	786	0.280371700300887	330	5910570			
SGTC_1818	st052136	56.3	µM	0.58026298936023	0.23498518365019	no	787	0.280868640924483	299	674169			
SGTC_3105	9121040	49.47	µM	0.579000297436416	0.235424147103161	no	788	0.281294486239536	269	41448907			
SGTC_2687	chenodiol	100	µM	0.578573103593503	0.235572759576142	no	789	0.281438628728104	293	5702181	A cholesterol synthesis inhibitor.		
SGTC_592	k241-0073	46.5	µM	0.577227616272099	0.236041166608044	no	790	0.281892851857029	310	4230158			
SGTC_2791	5663188	71.43	µM	0.577132213462122	0.236074398840364	no	791	0.281925072301489	334	54690634			
SGTC_2418	pentamidine	31.67	µM	0.576867062096384	0.236166774140616	no	792	0.282014631337514	292	4735	Thought to act by inhibiting tRNA aminoacylation and translation.		
SGTC_291	SEC14.278	35.5	µM	0.575936948435736	0.236490971051817	no	793	0.282328900115722	304	1068044			
SGTC_722	3534-0461	190	µM	0.574566914896741	0.236968950543075	no	794	0.282792116603761	296	658262			
SGTC_1634	st006576	41	µM	0.574407925941959	0.237024453229698	no	795	0.282845895348022	313	3915356			
SGTC_332	4112-0506	40.9	µM	0.573108117515568	0.237478481287697	no	796	0.283285745653455	313	2790355			
SGTC_2167	5876490	200	µM	0.571296853376953	0.238111958132018	no	797	0.283899217168166	320	686534			
SGTC_2052	5265182	7.135	µM	0.570064680429287	0.2385434306245	no	798	0.284316914744517	313	1239884			
SGTC_524	r073-0010	27.8	µM	0.56933924057587	0.238797659386535	no	799	0.284562970819082	334	2772106			
SGTC_228	caffeine	993.056	µM	0.568733680759829	0.239009989906304	no	800	0.284768443596596	290	2519	Caffeine is a phosphodiesterase inhibitor.		
SGTC_1508	1080-0625	72.9	µM	0.56852280011603	0.23908395628331	no	801	0.284840014222128	316	767111			
SGTC_746	1095-0025	46.6	µM	0.568462532490256	0.239105097449174	no	802	0.284860469983744	321	6749286			
SGTC_2482	5981709	142.65	µM	0.567659569103407	0.239386864921001	no	803	0.285133074990926	321	877755			
SGTC_2763	lisinopril	49.32	µM	0.564775450594578	0.240400423370283	no	804	0.286113253479699	325	5362119	A lysine-analog of enalapril and an ACE inhibitor.		
SGTC_2262	9014885	67.46	µM	0.562512842068551	0.241197199474167	no	805	0.286883328239769	312	6457424			
SGTC_167	3672-0051	66.205	µM	0.561565998072728	0.241531055493326	no	806	0.287205876132842	322	3237971			
SGTC_1244	0416-0015	52.5	µM	0.561558496771428	0.241533701444437	no	807	0.287208432179779	324	96201			
SGTC_2158	5657123	3.6195	µM	0.559949568369991	0.242101586032734	no	808	0.287756918586922	361	2858827			
SGTC_1580	hydrocortisone 21-hemisuccinate	43.2	µM	0.556033619223291	0.243486772866782	no	809	0.289093936179081	306	16623	A steroid.		
SGTC_2186	6124449	200	µM	0.555247570470018	0.24376533656559	no	810	0.289362667488653	318	3834182		YLR033W	RSC58
SGTC_986	1493-0483	84	µM	0.5542515408471	0.244118561241221	no	811	0.289703354739145	337	40079			
SGTC_1079	idarubicin 	2.36	µM	0.553307403464543	0.244453637892393	no	812	0.290026466178461	339	636362	Idarubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.		
SGTC_2847	9005661	71.43	µM	0.552297320220596	0.244812393082726	no	813	0.290372333154159	308	2991449			
SGTC_72	0744-0168	198.391	µM	0.550531110781107	0.245440384964756	no	814	0.290977572218317	362	677577			
SGTC_1142	3253-1408	9.78	µM	0.5504984726483	0.245451997890898	no	815	0.290988762095219	326	256655			
SGTC_2127	5253358	187.912	µM	0.550496912401075	0.245452553047568	no	816	0.290989297025904	328	20612			
SGTC_1140	3229-1848	2.98	µM	0.549809181108075	0.24569732264757	no	817	0.291225130388462	324	2849525			
SGTC_2819	7996655	46.38	µM	0.549589049866883	0.245775696968822	no	818	0.29130063553545	312	6456960			
SGTC_2997	9067075	71.4286	µM	0.549133527757944	0.245937921179	no	819	0.291456908898537	333	27209819			
SGTC_1250	0485-0349	40.2	µM	0.548044187704544	0.246326098640217	no	820	0.291830781051165	321	6842794		YDL195W	SEC31
SGTC_920	mycophenolic acid	780.421	nM	0.544973846529149	0.247421954785239	no	821	0.292885752628763	305	446541	Mycophenolic acid is a potent reversible inhibitor of IMPDH (inosine monophosphate dehydrogenase), leading to a depletion of GMP and inhibition of de novo synthesis of purines. The resulting imbalance of nucleotide pools also results in inhibiting transcription-elongation.		
SGTC_1567	st069303	68.4	µM	0.544465111489109	0.247603782128059	no	822	0.29306072518407	339	5581319			
SGTC_2857	9024691	58.44	µM	0.54378595239361	0.2478466320554	no	823	0.293294388337888	342	16478292			
SGTC_3303	9125618	40.5795	µM	0.543592073585712	0.247915981481592	no	824	0.293361107743984	331	22695467			
SGTC_1629	st005085	44.9	µM	0.5430376932856	0.248114337519791	no	825	0.293551925123032	322	24207091			
SGTC_566	0958-0068	16.5	µM	0.542844652410528	0.248183426981303	no	826	0.293618383169044	318	6815365			
SGTC_2572	astragaloside iv	100	µM	0.542804628470746	0.24819775286085	no	827	0.293632163054335	312	45006101	An anti-inflammatory agent.		
SGTC_2319	6033012	152.6	µM	0.542679326275143	0.248242605473848	no	828	0.293675305417734	312	847246			
SGTC_1617	st002906	78	µM	0.540315693868573	0.249089489861844	no	829	0.294489668566826	334	5150859			
SGTC_758	0868-0029	16	µM	0.5400260445251	0.249193376207478	no	830	0.294589535657757	300	762687			
SGTC_2425	5628681	7.85	µM	0.539877830500344	0.249246543924775	no	831	0.294640643847898	332	5714958			
SGTC_536	3852-0578	10.6	µM	0.539299543352974	0.24945404625008	no	832	0.294840091941785	332	2869208			
SGTC_500	h-89	112	µM	0.539099358863917	0.249525898294109	no	833	0.294909148981678	347	449241	Protein kinase A inhibitor; also known to inhibit several other kinases.		
SGTC_16	erodoxin	22.806	µM	0.539032720470441	0.249549819193877	no	834	0.29493213868098	326	3967339	Erodoxin inhibits Ero1.	YML130C	ERO1
SGTC_3058	9093861	49.47	µM	0.538813261578932	0.249628606028185	no	835	0.295007856036615	337	17217477			
SGTC_2939	9044578	71.43	µM	0.538654408477833	0.249685643324351	no	836	0.295062668865827	339	2653634			
SGTC_3068	9116768	49.47	µM	0.538030828198464	0.249909611000517	no	837	0.295277882801012	334	41904888			
SGTC_2716	st080858	38.6235	µM	0.537585371243368	0.25006966843436	no	838	0.295431665922153	312	5296050			
SGTC_1896	st058441	89	µM	0.53553867644465	0.2508057661262	no	839	0.296138710288907	318	688759			
SGTC_1875	nocodazole	6	µM	0.534142646670426	0.25130850821348	no	840	0.296621423037598	314	4122	A microtubule depolymerizer.	YJL014W	CCT3
SGTC_2306	7482397	179.52	µM	0.534060144883263	0.251338235649028	no	841	0.296649961401154	356	891448			
SGTC_3064	1327-0027	10	µM	0.533933096243977	0.251384018053134	no	842	0.296693911517465	318	16000455		YPR107C	YTH1
SGTC_1402	3909-7673	35.9	µM	0.533885869812726	0.2514010373801	no	843	0.296710249384079	312	5328014			
SGTC_2004	4023728	41.89	µM	0.533573738892807	0.251513537545914	no	844	0.296818240657995	351	360084		YDR527W	RBA50
SGTC_3125	9127534	49.47	µM	0.529326384458454	0.253047035399982	no	845	0.298289527832369	310	1639235			
SGTC_713	1488-1073	324	µM	0.529040879935883	0.253150292325244	no	846	0.298388545834757	347	3312542			
SGTC_1714	st033236	13.627	µM	0.528447774033775	0.253364868646567	no	847	0.298594293222798	332	2916566			
SGTC_2943	9068529	45.32	µM	0.528318094037488	0.25341179754877	no	848	0.298639287578479	344	3270634			
SGTC_2802	7925815	54.55	µM	0.528133730607867	0.253478523283808	no	849	0.298703260451156	328	1262923			
SGTC_2230	bromochlorosalicylanilide	954.5	nM	0.527560116653133	0.253686187549669	no	850	0.298902340477604	316	77254			
SGTC_372	0155-0182	15.9	µM	0.527108333123104	0.253849808674851	no	851	0.299059180123163	302	771486			
SGTC_1667	st014849	34.6	µM	0.527096847750847	0.253853969020582	no	852	0.299063167833216	310	5348460			
SGTC_152	4469-0003	551.229	µM	0.526409915837013	0.254102861397523	no	853	0.299301713811015	328	697280			
SGTC_2430	5571206	200	µM	0.525387648359138	0.254473490966885	no	854	0.299656869099913	336	1731771			
SGTC_2471	5466956	24.79	µM	0.524228689240437	0.254894021314669	no	855	0.300059744441914	317	724419			
SGTC_2034	5197015	53.07	µM	0.524026582801792	0.254967393215153	no	856	0.300130025411463	351	780676			
SGTC_374	0880-0231	82.3	µM	0.523151394760121	0.255285245422606	no	857	0.30043445124732	332	6833587			
SGTC_2266	7929956	200	µM	0.521244389087328	0.255978551593894	no	858	0.301098267655633	328	2967153			
SGTC_1908	st060353	56.5	µM	0.520760491988216	0.256154632134551	no	859	0.301266814204684	346	4227716			
SGTC_2394	5221648	200	µM	0.519382491474629	0.2566564049611	no	860	0.301747019185013	340	788586			
SGTC_1366	1683-0113	21.9	µM	0.51916782905137	0.256734616272272	no	861	0.301821855614314	324	708623			
SGTC_2269	7935389	174.42	µM	0.518984848866232	0.25680129409372	no	862	0.301885653446531	345	97605			
SGTC_623	k072-0108	16.9	µM	0.518814983591223	0.256863200919968	no	863	0.30194488405998	346	5382803			
SGTC_2839	9003951	25.97	µM	0.518196303284205	0.257088742508985	no	864	0.302160656875983	317	2990634			
SGTC_80	0159-0065	512.242	µM	0.517999012756074	0.257160686960202	no	865	0.302229479069865	318	1548079			
SGTC_1534	6-azauridine	81.6	µM	0.517710262645342	0.257266002158248	no	866	0.302330218410662	327	233502	6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP; used in antiviral studies.	YHR062C	RPP1
SGTC_2970	9090938	41.86	µM	0.517027933662849	0.257514955572354	no	867	0.302568329655864	341	17217104			
SGTC_2858	9025781	8.96	µM	0.516776045129809	0.257606890816145	no	868	0.302656252028144	312	4894980		YPL153C	RAD53
SGTC_2191	5911152	200	µM	0.516197043479825	0.257818281660135	no	869	0.302858397502566	326	2875902			
SGTC_791	1348-1292	225	µM	0.513336543907891	0.258863956398497	no	870	0.303857962672469	330	5437054			
SGTC_2468	5987765	72.9	µM	0.512633331403236	0.259121356050064	no	871	0.304103916495535	329	26772094			
SGTC_1282	0886-0010	32.4	µM	0.512084094003119	0.259322487582908	no	872	0.304296078060645	353	2836211		YNL267W	PIK1
SGTC_2179	6298986	200	µM	0.509609650077726	0.260229631884707	no	873	0.305162480913167	330	738374			
SGTC_1267	0828-0272	9.49	µM	0.509428810403987	0.260295992737192	no	874	0.305225843108855	327	745334			
SGTC_1301	naphtanilide LB	4.81	µM	0.508921215232284	0.260482306226125	no	875	0.305403724339815	329	67238	An a1-adrenergic receptor antagonist or alpha blocker.		
SGTC_208	k072-0098	12.366	µM	0.508817574216313	0.260520356240762	no	876	0.305440049862357	332	5948901			
SGTC_638	3970-0837	4.09	µM	0.508777095758084	0.260535217986899	no	877	0.305454237826927	327	4118451		YLR208W	SEC13
SGTC_1455	4262-0120	131	µM	0.507295417657163	0.261079519303266	no	878	0.305973776658788	325	1529587			
SGTC_2094	5332512	191.667	µM	0.506906560521258	0.261222464548636	no	879	0.306110191121557	339	755774			
SGTC_320	4092-0846	5.34	µM	0.50130405458972	0.263286419654545	no	880	0.308078576095183	338	1359356			
SGTC_2338	7999974	200	µM	0.500350421270809	0.263638564426688	no	881	0.308414178356639	352	315925			
SGTC_933	2914-0560	114	µM	0.500317078293009	0.263650881215223	no	882	0.308425915303594	313	463887			
SGTC_1444	4112-3581	28	µM	0.500262668944516	0.263670980483517	no	883	0.308445068171687	339	2877249			
SGTC_2019	4016004	108	µM	0.499594708312639	0.263917794409126	no	884	0.308680242331084	336	45595336			
SGTC_1785	bathophenanthroline	24	µM	0.499264913142664	0.264039698357673	no	885	0.30879638486299	332	72812	An iron chelator.		
SGTC_1783	st039459	87.517	µM	0.498997859124887	0.264138431978441	no	886	0.308890446129935	395	729761			
SGTC_7	0192-1582	4.227	µM	0.498844771050252	0.264195039269054	no	887	0.308944372178325	350	252616			
SGTC_3256	9138902	49.47	µM	0.498190034103116	0.264437210681673	no	888	0.309175053039185	366	17228773			
SGTC_2288	7946289	167.31	µM	0.497114308021559	0.264835340977276	no	889	0.309554222687612	358	1246052			
SGTC_2310	7668677	200	µM	0.496465471323912	0.265075625130402	no	890	0.309783021351511	372	2197143			
SGTC_3231	9132313	49.47	µM	0.495026961365709	0.265608744183392	no	891	0.310290544514814	342	4905967			
SGTC_424	splitomicin	100	mM	0.494258709030675	0.265893684966326	no	892	0.310561741088325	348	5269	Sir2p (silent information regulator) and HDAC inhibitor.		
SGTC_2955	9076254	12.21	µM	0.492744233806001	0.266455849207375	no	893	0.311096659275985	327	16459619			
SGTC_655	k060-0012	42	µM	0.492103269204123	0.266693952422666	no	894	0.311323170638755	373	5994525			
SGTC_1281	0884-0031	11.8	µM	0.491630008494081	0.26686982659982	no	895	0.311490462755294	345	1548255			
SGTC_1697	st025554	27.742	µM	0.491014865075988	0.267098515087215	no	896	0.311707966926252	334	1269519			
SGTC_1316	1272-0050	65.9	µM	0.490694113784961	0.267217798264703	no	897	0.31182140515256	339	7340392			
SGTC_1275	0867-0008	21.1	µM	0.490507718911354	0.267287128410728	no	898	0.31188733453696	343	3422836			
SGTC_2199	6590217	200	µM	0.490352201769232	0.267344980434454	no	899	0.311942346829297	339	703109			
SGTC_140	0062-0056	502.533	µM	0.487080000684087	0.268563694745867	no	900	0.313100819282485	319	3758964			
SGTC_581	0958-0271	211	µM	0.486720310266064	0.268697829722429	no	901	0.313228275038601	323	4591145			
SGTC_2921	7974240	10.71	µM	0.484129241330586	0.269665079041123	no	902	0.314147075003349	330	2979074		YDR527W	RBA50
SGTC_463	ikarugamyin	104	µM	0.482586531059843	0.270241801976312	no	903	0.314694672231924	369	54714554	An antiprotozoal antibiotic found to inhibit cholesteryl ester accumulation in macrophage. Shown to be efficient inhibitor of clathrin-dependent endocytosis.		
SGTC_2129	girgensonine	121.053	µM	0.481031914613886	0.270823599133147	no	904	0.315246908215558	352	442638	Galangin is a flavonoid found in medicinal herbs. An inhibitor of cancer cell proliferation, galangin is used to study mechanisms of genotoxicity.		
SGTC_1784	st039334	36.3	µM	0.480728059201284	0.270937386490402	no	905	0.315354893034809	362	3496984			
SGTC_3177	9107506	49.47	µM	0.478605660976835	0.271732843878508	no	906	0.316109595163753	348	8897194			
SGTC_994	3910-0338	138	µM	0.478149246427538	0.271904056035676	no	907	0.316271991596537	336	3479481			
SGTC_1253	0550-0034	176	µM	0.477633457370891	0.27209760557844	no	908	0.316455556676365	329	5969915			
SGTC_1713	st033146	12.748	µM	0.474922623537689	0.273115969044556	no	909	0.317421062755518	366	674619			
SGTC_2524	avocatin b	10.57	µM	0.474125599164408	0.273415741552988	no	910	0.317705172372722	340	6710748			
SGTC_2699	st077704	54.6	µM	0.473059676556991	0.273816905071221	no	911	0.318085302045219	330	645852			
SGTC_649	1123-0311	367	µM	0.470260181820505	0.27487188827967	no	912	0.319084570930746	351	693629		YIL048W	NEO1
SGTC_225	nsc-122657	1.016	µM	0.469774305219344	0.275055193579885	no	913	0.319258136949596	352	275685			
SGTC_3143	9086658	49.47	µM	0.46893517793562	0.275371910494739	no	914	0.319557985318834	353	25236626			
SGTC_468	gf-109203x	121	µM	0.468379621531965	0.275581696215548	no	915	0.319756569226262	329	2396	A protein kinase C inhibitor.		
SGTC_2612	dictamnine	15.46	µM	0.468169276977681	0.275661145711387	no	916	0.319831770480259	336	68085	A quinoline derivative and established mutagen.	YOR116C	RPO31
SGTC_407	eburnamonine	100	µM	0.467859129638327	0.275778312376299	no	917	0.319942666199032	333	3195			
SGTC_2459	5811157	9.22	µM	0.465913270607368	0.276513971957308	no	918	0.320638790892242	352	2870684		YBR192W	RIM2
SGTC_2187	6125751	200	µM	0.465389568654541	0.276712129095818	no	919	0.320826251468946	347	874498			
SGTC_1115	galangin	695.678	nM	0.464843335679223	0.27691888557603	no	920	0.321021825773072	377	5281616	Galangin is a flavonoid found in medicinal herbs. An inhibitor of cancer cell proliferation, galangin is used to study mechanisms of genotoxicity.		
SGTC_2220	6782180	200	µM	0.464348320367567	0.277106320800148	no	921	0.321199104905865	345	833803			
SGTC_3070	9117005	49.47	µM	0.464117537098598	0.277193727015756	no	922	0.321281768922449	344	8779016			
SGTC_1029	k015-0030	64.7	µM	0.464061596831624	0.277214915708145	no	923	0.3213018074413	337	2208316			
SGTC_966	1300-0360	30.2	µM	0.462550944778013	0.277787410124951	no	924	0.321843138863712	356	70588			
SGTC_1588	farnesol	29.9	µM	0.462346168625002	0.277865058906272	no	925	0.321916548086415	358	445070	Farnesol is a polyprenyl alcohol found in plant essential oils. Induces apoptosis in cell cultures.		
SGTC_831	k061-1017	217	µM	0.461616817139546	0.278141706713659	no	926	0.322178066255854	374	1240153			
SGTC_2603	homopterocarpin	100	µM	0.461495764251225	0.278187635864326	no	927	0.322221479818916	350	101795	A weak amylase inhibitor.		
SGTC_1457	k015-0032	57.3	µM	0.461054626718687	0.278355040874171	no	928	0.322379706825025	349	4302660			
SGTC_2178	5812956	200	µM	0.460385652829982	0.278608999977887	no	929	0.322619715473389	333	5403383			
SGTC_2545	solidagenone	89.61	µM	0.460207929286907	0.278676487214521	no	930	0.322683490017268	342	6708572	An anti ulcer agent		
SGTC_1708	st033234	31.827	µM	0.45677265940411	0.279982529046413	no	931	0.323917229632549	326	674664			
SGTC_1292	0kpi-0043	232	µM	0.456076463108374	0.280247574395658	no	932	0.324167497400236	364	3333905			
SGTC_2042	p-Dimethylaminoacetophenone	200	µM	0.455988009898379	0.280281257667173	no	933	0.324199300141132	348	75037	A free radical scavenger.		
SGTC_1935	st074532	41.6	µM	0.454685714924345	0.280777402680453	no	934	0.324667679673243	383	2829742			
SGTC_3045	9092950	49.47	µM	0.454598379125759	0.280810690839987	no	935	0.324699100539851	345	44120432			
SGTC_1246	0422-0085	105	µM	0.453653989023476	0.281170768251886	no	936	0.325038944124461	398	264295			
SGTC_2959	9079155	11	µM	0.452574594614891	0.281582593041098	no	937	0.32542754802626	377	16189457			
SGTC_3076	9116187	49.47	µM	0.451813977028284	0.281872968515097	no	938	0.325701499867434	381	27241210			
SGTC_1876	myriocin	605	nM	0.451066211856898	0.282158577987813	no	939	0.325970914440083	386	301119	Myriocin is a very potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis.[2] Due to this property, it is used in biochemical research as a tool for depleting cells of sphingolipids.	YMR296C	LCB1
SGTC_988	1497-1057	103	µM	0.450979679076881	0.282191638239893	no	940	0.32600209746644	380	3533044			
SGTC_1400	3771-8998	51.5	µM	0.449519343808635	0.282749847193385	no	941	0.326528528540112	365	670767			
SGTC_3347	9188721	44.724	µM	0.449500528428982	0.282757042778404	no	942	0.326535313487082	396	44118411		YKL104C | YBL026W	GFA1 | LSM2
SGTC_3277	9138724	49.47	µM	0.449354336172967	0.282812954230577	no	943	0.326588033310202	357	15943418			
SGTC_1176	0848-0131	83.3	µM	0.447748195171621	0.28342757472988	no	944	0.327167467416943	368	6769040			
SGTC_1950	st077106	7.18	µM	0.446515543960037	0.283899706086861	no	945	0.327612443505448	331	13831864			
SGTC_1121	fusaric acid	630.51	nM	0.446253819696983	0.284000000413592	no	946	0.327706955177524	326	3442	Fusaric acid is a small molecule inhibitor of dopamine β-hydroxylase, an enzyme responsible for the conversion of dopamine to norepinephrine. May also act as an ETC uncoupler.		
SGTC_2275	7947463	200	µM	0.446152890445756	0.284038681644171	no	947	0.327743404852371	358	1225414			
SGTC_2510	benzyl isothiocyanate	8.31	µM	0.445702549961599	0.284211305763995	no	948	0.327906061190869	355	2346	DNA damaging agent; causes G2/M arrest.		
SGTC_2976	9009005	19.48	µM	0.444739182080645	0.284580751427526	no	949	0.328254125054945	339	2993148			
SGTC_1532	4',5'-dihydroxyflavone	78.7	µM	0.444724375423761	0.284586431478468	no	950	0.32825947585	347	165521			
SGTC_577	r071-0003	38.6	µM	0.444506790475284	0.284669906501267	no	951	0.328338110252845	369	4568517		YMR134W	ERG29
SGTC_1010	4112-3296	15.2	µM	0.443766489166518	0.28495400569573	no	952	0.328605709375153	341	704384			
SGTC_1581	himbacine	57.9	µM	0.442973128927325	0.285258616897155	no	953	0.328892585483495	372	5281825	An alkaloid muscarinic receptor antagonist.		
SGTC_1183	1254-0324	198	µM	0.441872111317079	0.285681610228218	no	954	0.329290876394375	330	5799357			
SGTC_822	1487-0950	154	µM	0.440948035390049	0.286036855573808	no	955	0.329625308622352	350	1958375			
SGTC_1911	st060208	74.3	µM	0.440599327263014	0.286170965042146	no	956	0.329751544979953	371	688783			
SGTC_2452	5863136	48.41	µM	0.439772215461198	0.286489182898153	no	957	0.330051046520918	347	2184096			
SGTC_464	bw-b 70c	158	µM	0.439769841377117	0.286490096530112	no	958	0.330051906346175	378	5353454			
SGTC_3174	9107204	49.47	µM	0.439377728618142	0.28664101442718	no	959	0.330193930672386	362	3938802			
SGTC_2237	6667747	47.222	µM	0.439125233079544	0.286738215851976	no	960	0.330285398208483	400	729940		YDL015C	TSC13
SGTC_794	k038-0031	316	µM	0.438963733649968	0.286800395339844	no	961	0.330343907352345	358	6624242			
SGTC_2211	7117706	200	µM	0.438953296111138	0.286804414154819	no	962	0.330347688879693	363	822771			
SGTC_3349	9149703	23.001	µM	0.438386397755069	0.287022729795242	no	963	0.330553102552116	346	4910494			
SGTC_678	1218-2179	85.9	µM	0.43501046672567	0.288324446402935	no	964	0.331777415060695	373	6820081		YOR116C	RPO31
SGTC_425	3825-7017	13.1	µM	0.434851210862783	0.288385922158843	no	965	0.331835215198397	408	3397440			
SGTC_3313	9133968	57.047	µM	0.434123598253717	0.288666872881039	no	966	0.332099344978249	353	1494643			
SGTC_2532	xanthone	78.9	µM	0.433066150102767	0.289075411599223	no	967	0.332483356689967	364	7020	An insecticide.		
SGTC_1368	1852-0141	284	µM	0.432724907250464	0.289207306730365	no	968	0.332607316400051	366	2838987			
SGTC_2249	haloperidol	116.36	µM	0.4319614665768	0.289502489621552	no	969	0.332884709754195	353	3559	Haloperidol is a D2, D3, and D4 dopamine antagonist of the typical antipsychotic class of medications. It is a butyrophenone derivative and has pharmacological effects similar to the phenothiazines.		
SGTC_3202	9113761	49.47	µM	0.431800196698577	0.289564862411241	no	970	0.332943318279172	380	4798415			
SGTC_1987	st072290	61.9	µM	0.431319813016837	0.289750693137658	no	971	0.333117922979158	377	54697379			
SGTC_2045	5106652	78.05	µM	0.431185875387871	0.289802515294419	no	972	0.333166611641384	363	673349			
SGTC_3251	9135047	49.47	µM	0.428881420886502	0.29069481803006	no	973	0.33400476080632	362	17682963			
SGTC_2602	kawain	100	µM	0.428876848057818	0.290696589941697	no	974	0.334006424807069	340	5369129			
SGTC_2731	amoxapine	43.43	µM	0.428784102947739	0.290732528555675	no	975	0.334040174410151	381	2170	A moderate and strong reuptake inhibitor of serotonin and norepinephrine.		
SGTC_236	1509-0011	5.31	µM	0.428076730883666	0.291006702677403	no	976	0.334297628631648	380	3107280			
SGTC_1072	oxiconazole	14.9	nM	0.427286648832031	0.291313077538898	no	977	0.334585278048067	339	47316	Oxiconazole is a topically used antifungal that acts by inhibiting lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YDL196W	YDL196W
SGTC_2462	5162487	171.77	µM	0.4243366183919	0.292458356825434	no	978	0.335660168644089	390	2259986			
SGTC_3003	9075612	71.4286	µM	0.423887935770899	0.292632730413135	no	979	0.335823771458737	384	6501993			
SGTC_1827	berberine	7.24	µM	0.423299527559455	0.29286147937284	no	980	0.336038369472449	373	629413	Berberine is a quaternary ammonium salt and isoquinoline alkaloid.		
SGTC_502	l-744,832	89.3	µM	0.422302639943712	0.293249217674486	no	981	0.336402065742277	396	6610354	L-744,832 is a Ras farnesyltransferase inhibitor that has been demonstrated to induce tumor regression. 		
SGTC_748	act1.228	77.9	µM	0.4199738088068	0.294155939924329	no	982	0.337252293566094	331	4421505		YNR035C	ARC35
SGTC_1466	k213-0079	57.5	µM	0.419718384651203	0.294255467209247	no	983	0.337345596505355	377	3657981			
SGTC_724	3910-0327	137	µM	0.419415994643813	0.294373315074478	no	984	0.337456068356723	390	2885483			
SGTC_1746	st038117	42	µM	0.41920825196829	0.294454289472587	no	985	0.33753197090924	355	2898218			
SGTC_113	0099-0221	2.5	µM	0.41752909177162	0.295109173316061	no	986	0.33814572494923	388	89219			
SGTC_1974	st069448	26.9	µM	0.417432014864376	0.29514705446834	no	987	0.33818122094812	348	6323587		YNR016C	ACC1
SGTC_175	3793-3120	23.7	µM	0.417295450527297	0.29520034811476	no	988	0.338231157890693	388	5322297			
SGTC_221	trifluoperazine	10.304	µM	0.417162352161318	0.295252293443357	no	989	0.338279830183735	381	5566	Phenothiazine antipsychotic; D2 dopamine receptor antagonist; inhibits calmodulin-dependent stimulation of 3′:5′-cyclic nucleotide phosphodiesterase; inhibits cAMP-gated cation channels.	YIL048W	NEO1
SGTC_2789	5281112	71.43	µM	0.416914687074966	0.295348962808385	no	990	0.33837040518733	345	765948			
SGTC_83	0170-0301	39.027	µM	0.415990874203941	0.295709676575192	no	991	0.338708340504803	357	3089716			
SGTC_3131	9127911	49.47	µM	0.415783899675241	0.295790520002399	no	992	0.338784070630426	346	45595681			
SGTC_3326	9140064	16.379	µM	0.413745006392229	0.296587445692905	no	993	0.339530431318124	374	1868434			
SGTC_1035	k081-0041	55.2	µM	0.41355282937123	0.296662611063425	no	994	0.339600812483037	398	731709			
SGTC_135	0933-0004	26.348	µM	0.413497434723913	0.296684278952923	no	995	0.339621100753707	375	21230617		YGL099W	LSG1
SGTC_1350	1495-0454	146	µM	0.412962360892936	0.296893613019958	no	996	0.339817095278063	386	1069057			
SGTC_1707	st032323	6.317	µM	0.41268904151109	0.29700056836984	no	997	0.339917227340859	350	3132057		YMR211W	DML1
SGTC_1576	erythromycin ethylsuccinate	23.2	µM	0.411015191878519	0.297655963390738	no	998	0.340530697552771	334	3256	An antibiotic and ribosome inhibitor.		
SGTC_2396	5342950	42.78	µM	0.409817373460828	0.298125373364979	no	999	0.340969960345435	382	1886677			
SGTC_2350	9023895	38.85	µM	0.407979336215435	0.298846332059039	no	1000	0.34164442278251	370	2997209			
SGTC_3122	9126309	49.47	µM	0.407545308277312	0.299016692374655	no	1001	0.341803761989981	431	17591206			
SGTC_1149	3909-7961	23.3	µM	0.406852645387651	0.299288660807838	no	1002	0.342058108964661	363	735261			
SGTC_1311	1190-0148	100	µM	0.404597856941842	0.300174761290481	no	1003	0.342886567039626	386	1961333			
SGTC_2313	7726885	200	µM	0.404403295254323	0.300251276893195	no	1004	0.342958088702402	348	726423			
SGTC_1169	aniline yellow	25.8	µM	0.404176801468415	0.300340361590529	no	1005	0.343041355822344	401	6051	A DNA damaging agent.		
SGTC_664	1222-0054	14.9	µM	0.403178462959428	0.300733171081552	no	1006	0.343408471142598	359	6813991			
SGTC_847	0342-0274	5.54	µM	0.401722121953989	0.301306603075371	no	1007	0.343944270995276	397	18097			
SGTC_1869	3',7'-dimethoxyflavone	40.3	µM	0.401341781169968	0.301456442709889	no	1008	0.344084253179444	363	688664			
SGTC_195	4234-0266	16.654	µM	0.401274978525213	0.301482763843551	no	1009	0.344108841705919	377	2303354			
SGTC_2609	2,3,4-trihydroxy-4'-ethoxybenzophenone	70	µM	0.401234103741976	0.301498869563691	no	1010	0.344123887104307	348	6708739		YPR165W	RHO1
SGTC_1679	SEC14.276	6.7	µM	0.400250404120055	0.301886589333359	no	1011	0.344486046648331	403	1005053		YMR079W	SEC14
SGTC_895	0964-0006	13.7	µM	0.398760986030628	0.302474061238406	no	1012	0.345034663210301	389	6738897			
SGTC_339	3091-4833	71.4	µM	0.398659451405926	0.302514128246171	no	1013	0.34507207464572	363	3240077			
SGTC_700	3453-2283	142	µM	0.398084419267262	0.3027410889907	no	1014	0.345283979481982	363	565664			
SGTC_1427	4048-4900	550	nM	0.398007617925685	0.302771407659829	no	1015	0.345312285183703	383	24132586			
SGTC_769	0302-0231	76	µM	0.396829962651422	0.303236477804735	no	1016	0.345746427004015	383	571869		YER009W	NTF2
SGTC_449	xestospongin c	11.1929	µM	0.396706206409448	0.30328536916396	no	1017	0.345792061451115	400	5311502	Synthetic form of the macrocyclic bis-1-oxaquinolizidine isolated from the Okanowan marine sponge.	YIL048W	NEO1
SGTC_2437	5741531	144.16	µM	0.395849137263346	0.303624061068809	no	1018	0.346108162533575	384	2262990			
SGTC_2881	9058953	51.95	µM	0.394651370726691	0.304097670566475	no	1019	0.346550098021637	336	17122249			
SGTC_2449	5812982	45.77	µM	0.393307786265591	0.304629329427379	no	1020	0.347046084042045	378	776185			
SGTC_1778	st046819	58.9	µM	0.392542022719476	0.304932528313509	no	1021	0.347328884029992	425	671715			
SGTC_879	0831-1030	162	µM	0.391551864428769	0.305324773391932	no	1022	0.347694680047635	362	1549252			
SGTC_3214	9129694	49.47	µM	0.390830249988107	0.305610777402971	no	1023	0.347961356786052	413	17158655			
SGTC_2541	muurolladie-3-one	83.07	µM	0.390177738627287	0.305869495317766	no	1024	0.348202560850882	402	3989419	Muurolladie-3-one is a natural monoterpene ketone which is a component of some essential oils. 	YMR203W	TOM40
SGTC_666	0272-0154	136	µM	0.389588290874401	0.306103292102898	no	1025	0.348420505942648	373	6870312			
SGTC_2185	6113692	200	µM	0.38925239142085	0.306236557596476	no	1026	0.348544725327067	379	874150			
SGTC_237	nikkomycin	200	µM	0.388917749142583	0.30636934981343	no	1027	0.348668495945616	387	353481	Nikkomycin inhibits chitin synthase from converting UDP-GlcNAc into cell wall chitin due to its structural resemblance to UDP-N-acetylglucosamine.		
SGTC_2096	5468907	200	µM	0.388906011915955	0.306374007822841	no	1028	0.348672837362627	373	759785			
SGTC_2092	5303694	80.6725	µM	0.387689042876939	0.306857141124955	no	1029	0.349123082679013	381	1963699			
SGTC_1890	3',4',7',8'-tetrahydroxyflavone	14.9	µM	0.386526679565026	0.307318909562719	no	1030	0.349553323766534	408	688798			
SGTC_1881	5652484	16	µM	0.386034005307696	0.307514724992506	no	1031	0.349735742253546	392	2255129			
SGTC_287	k060-0039	29.6	µM	0.385083406969941	0.307892699273463	no	1032	0.350087810589275	368	5861974			
SGTC_2054	5233173	129	µM	0.384455918343639	0.308142311324432	no	1033	0.35032028104658	350	6889			
SGTC_2206	7254556	146.969	µM	0.384176939987814	0.308253316125406	no	1034	0.350423654284356	362	4398905			
SGTC_2550	chrysin dimethyl ether	71.87	µM	0.383748290758519	0.308423908770769	no	1035	0.350582508476731	370	88881	An O-methylated flavonoid and antioxidant.		
SGTC_1891	st059073	26.2	µM	0.382334339293759	0.308986922464583	no	1036	0.351106693433143	421	688754			
SGTC_1870	st057514	26.5	µM	0.379444511095024	0.310139003275666	no	1037	0.352178901188761	362	5393161			
SGTC_3160	9100216	49.47	µM	0.378959885981348	0.310332390618645	no	1038	0.352358826159594	385	17191039			
SGTC_1349	flufenamic acid	69	µM	0.378732566896139	0.310423119291766	no	1039	0.352443233462525	389	3371	A non-steroidal anti-inflammatory.		
SGTC_2248	tofa	1.1	µM	0.378190760164887	0.310639414275952	no	1040	0.352644444479765	390	115175	TOFA (5-(Tetradecyloxy)-2-furoic acid) is a cell-permeable, potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in fatty acid biosynthesis. Inhibits cellular fatty acid synthesis in a dose-dependent manner		
SGTC_1243	0416-0003	5.65	µM	0.377225741860539	0.311024821925989	no	1041	0.353002925867445	383	2141977			
SGTC_1566	6,7-dimethoxy-4-ethylcoumarin	85.4	µM	0.376988120896317	0.311119754481449	no	1042	0.353091216451209	380	688761			
SGTC_2975	9084847	53.72	µM	0.376698830835912	0.311235346452105	no	1043	0.353198715910225	353	27211724			
SGTC_992	3909-8734	162	µM	0.376526205901662	0.311304331270773	no	1044	0.353262868483399	390	4288319			
SGTC_2628	lathosterol	100	µM	0.375940951103261	0.311538261604264	no	1045	0.35348039764263	370	6710616			
SGTC_3329	9141233	27.5565	µM	0.375552639485281	0.311693514406195	no	1046	0.353624752822666	382	4909101		YNL103W	MET4
SGTC_1404	3909-7820	48.3	µM	0.374382212509921	0.312161671078687	no	1047	0.354059987350342	382	23741373			
SGTC_286	k060-0067	22.9	µM	0.373734174988391	0.312421008861272	no	1048	0.354301048415517	358	5985051			
SGTC_2447	5741742	33.78	µM	0.373464461641026	0.312528972695787	no	1049	0.354401395292896	361	1776504			
SGTC_163	TUB2.036	7.546	µM	0.372117956971598	0.313068206991923	no	1050	0.354902513561825	375	15992207		YJR013W	GPI14
SGTC_2298	7976326	193.81	µM	0.371431710936448	0.313343181706491	no	1051	0.355158005128397	372	2235818			
SGTC_3085	9117376	49.47	µM	0.37057913952537	0.313684946585544	no	1052	0.355475510869446	387	16480349			
SGTC_3079	9117512	49.47	µM	0.369300402292302	0.314197845675201	no	1053	0.355951912864021	433	7185044			
SGTC_510	ag-490	170	µM	0.369137779239975	0.314263099226181	no	1054	0.356012515298043	372	5328779			
SGTC_1178	0988-0033	191	µM	0.368778505121556	0.314407280866336	no	1055	0.356146413800017	375	5392207			
SGTC_639	0833-0042	114	µM	0.367302300836602	0.314999998933535	no	1056	0.356696769017215	407	5978911		YPR085C | YHR062C	ASA1 | RPP1
SGTC_86	0417-1630	471.922	µM	0.366907520105267	0.315158590149322	no	1057	0.356844000925899	380	3634867			
SGTC_450	aminopyrene	156	nM	0.364883304236651	0.315972292400501	no	1058	0.357599258819443	414	15352	Aminopyrene is an established DNA mutagen.	YPR165W	RHO1
SGTC_2030	5175110	200	µM	0.36434057002767	0.316190614709816	no	1059	0.35780185408795	410	2831986			
SGTC_1091	telmisartan	47.6	µM	0.364269027467124	0.316219398473264	no	1060	0.357828562938678	392	65999	Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.		
SGTC_2837	9008476	45.46	µM	0.363151740311421	0.316669061737666	no	1061	0.358245767911945	394	2992805			
SGTC_2003	4023581	200	µM	0.362875194648071	0.316780402147243	no	1062	0.358349058682935	382	16641307			
SGTC_2110	5483698	200	µM	0.362665131798626	0.316864986917759	no	1063	0.358427524818572	355	2848765		YHR062C	RPP1
SGTC_2021	4019055	173	µM	0.362076914804146	0.317101891716402	no	1064	0.358647277116398	374	44827708		YER133W	GLC7
SGTC_2204	7233102	200	µM	0.361680348624454	0.317261651341194	no	1065	0.358795456905227	404	2172480			
SGTC_252	miconazole	1.30953	nM	0.361430858740294	0.317362177645206	no	1066	0.358888691478166	398	4189	Miconazole, an imidazole, is a topically used antifungal that acts by inhibiting lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YDL196W	YDL196W
SGTC_2025	5147754	141	µM	0.35955916354535	0.318116764153418	no	1067	0.359588413282615	393	315777		YLR208W	SEC13
SGTC_2683	piperine	63.03	µM	0.35886055026508	0.3183986086134	no	1068	0.359849706425653	409	638024	Piperine is an alkaloid from black pepper that shows chemopreventive, cytotoxic, anti-inflammatory, and antioxidant effects. It is suggested that piperine exerts its chemopreventive effect by augmenting antioxidant defense system and modulating lipid peroxidation.		
SGTC_525	k781-2675	26.7	µM	0.3585952069596	0.318505684725823	no	1069	0.359948966468193	392	3651118		YDL195W	SEC31
SGTC_1057	3448-5381	134	µM	0.357682218645068	0.318874226003727	no	1070	0.360290570699732	387	5497911			
SGTC_1735	st034310	56.75	µM	0.357635377078931	0.318893139131816	no	1071	0.360308099978107	432	871153			
SGTC_1837	st055472	66.5	µM	0.35652196111362	0.319342839677607	no	1072	0.360724854281916	376	676091			
SGTC_2954	9074818	52.69	µM	0.355714655658105	0.319669070765309	no	1073	0.361027134185868	405	16648742			
SGTC_70	0141-0289	43.283	µM	0.35509956573038	0.319917721508514	no	1074	0.361257500987181	370	352408			
SGTC_2121	5257820	149.641	µM	0.354080056093189	0.320330037545723	no	1075	0.361639444033758	384	791256			
SGTC_1421	4029-0249	71.4	µM	0.353399422591329	0.32060542688034	no	1076	0.361894509319059	404	2894095			
SGTC_793	0488-0545	106	µM	0.352621491268958	0.320920304599039	no	1077	0.362186111797358	395	292548			
SGTC_1370	2001-0092	44.6	µM	0.351494742255017	0.321376599193474	no	1078	0.362608608122174	415	790957			
SGTC_2093	5331342	194.4	µM	0.350571535112202	0.321750667404585	no	1079	0.362954907251149	416	33839			
SGTC_443	clozapine	122	µM	0.350505504741375	0.321777428745452	no	1080	0.362979679837182	421	2818	An adrenergic, cholinergic, GABAA and histaminergic receptor agonist.	YIL048W	NEO1
SGTC_3155	9099265	49.47	µM	0.350197271587899	0.321902364285323	no	1081	0.363095327121227	415	25236499			
SGTC_1610	st001799	48.1	µM	0.348985090238187	0.322393890562917	no	1082	0.363550251497925	386	621897			
SGTC_2991	9074669	71.4286	µM	0.348855861106989	0.322446309901371	no	1083	0.36359876177901	418	17333109			
SGTC_629	3448-6466	76.7	µM	0.348287238346896	0.322677002834911	no	1084	0.363812238463173	408	573744			
SGTC_3071	9117417	49.47	µM	0.346520368148308	0.323394265732816	no	1085	0.364475839859277	414	45595590		YGL055W	OLE1
SGTC_1539	benzyladenosine	56	µM	0.344219287832645	0.324329376366048	no	1086	0.365340689016964	353	92208	A nucleotide analog.		
SGTC_1147	3809-1045	12.3	µM	0.343735587399373	0.324526083303574	no	1087	0.365522572630232	391	325925			
SGTC_563	tetrahydrosecaminediol	614	µM	0.343226103597756	0.324733328539096	no	1088	0.365714184146803	392	334274	A psychoactive constituent of the cannabis plant.		
SGTC_3334	9142812	21.919	µM	0.34311130642996	0.324780032642252	no	1089	0.365757362785531	394	45283678			
SGTC_1575	cyproterone acetate	48	µM	0.343040731300779	0.324808746809571	no	1090	0.365783909040815	411	9880	An androgen receptor antagonist and liver toxin.		
SGTC_402	epigallocatechin gallate	10	µM	0.34272420528218	0.324937541254196	no	1091	0.365902975606836	409	65064	An antioxidant.		
SGTC_2303	7774051	200	µM	0.342282437489341	0.325117331561483	no	1092	0.366069175557488	411	2953184			
SGTC_1927	st060202	13.8	µM	0.34221668528694	0.325144094823731	no	1093	0.366093914713513	394	688887			
SGTC_2866	9034245	58.44	µM	0.342216626406326	0.32514411879044	no	1094	0.366093936867494	431	6462273			
SGTC_1958	st076513	41.9	µM	0.340639416524945	0.325786364064877	no	1095	0.366687526066197	409	732122		YGL099W	LSG1
SGTC_2370	9071495	200	µM	0.336707185753329	0.327389831561468	no	1096	0.368168822962246	414	21791103			
SGTC_1743	st037606	46.3785	µM	0.334282109390855	0.328380310781156	no	1097	0.36908334467711	355	590142		YLR208W | YDL195W	SEC13 | SEC31
SGTC_741	4582-0002	126	µM	0.332475437938622	0.329118998877702	no	1098	0.369765141770902	403	2912688			
SGTC_2429	5902844	64.44	µM	0.331617039774378	0.329470203625219	no	1099	0.370089225575932	413	1927790		YGL093W | YPR107C	SPC105 | YTH1
SGTC_2958	9077254	16.72	µM	0.330998291018281	0.329723451640675	no	1100	0.370322888217301	377	16457351			
SGTC_1152	3909-8331	15.9	µM	0.330849753005228	0.32978425847236	no	1101	0.3703789888459	424	16001939			
SGTC_2636	apigenin dimethyl ether	100	µM	0.330470558067985	0.329939509457362	no	1102	0.370522217711748	404	5281601	Natural flavone that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase.		
SGTC_67	0335-0847	266	µM	0.33024035842822	0.330033772690082	no	1103	0.370609177084685	415	4552207		YOR254C	SEC63
SGTC_2933	9026794	32.47	µM	0.329371282535242	0.330389743218399	no	1104	0.370937535569898	429	17586027			
SGTC_2777	climbazole	1.536	µM	0.328595306839577	0.330707709981535	no	1105	0.37123079793137	407	37907	Climbazole, an imidazole, is topically used antifungal; inhibits lanosterol 14α-demethylase, preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YLR127C	APC2
SGTC_1968	st069590	43.6	µM	0.328523935908105	0.330736961346939	no	1106	0.371257774709277	403	6384066			
SGTC_387	norethindrone acetate	66.7	µM	0.327865332706945	0.331006938529232	no	1107	0.371506743318754	409	541197			
SGTC_1665	st014639	11.4	µM	0.327003898425936	0.331360193673043	no	1108	0.371832468327563	412	981133		YIL048W	NEO1
SGTC_514	4466-0038	2.65	nM	0.326233499093714	0.331676244558473	no	1109	0.372123848995983	388	5722064			
SGTC_817	1391-0715	46	µM	0.325836768161311	0.331839047390789	no	1110	0.37227392926917	416	1353946			
SGTC_1081	sertraline	6	µM	0.325250818212163	0.332079556382058	no	1111	0.372495625130438	412	63009	A selective serotonin uptake inhibitor that is used in the treatment of depression. Also called zoloft.	YGL099W	LSG1
SGTC_1832	st054113	55	µM	0.324730896806506	0.332293021241899	no	1112	0.372692374283997	418	1251267			
SGTC_1269	0831-0796	3.05	µM	0.323820044930077	0.332667122117219	no	1113	0.37303713976991	407	927758			
SGTC_1062	mesoridazine	14.2	µM	0.323501633130534	0.332797938080207	no	1114	0.373157685454439	404	4078	A neuroleptic.		
SGTC_2800	7887935	81.82	µM	0.323358296191315	0.332856833120556	no	1115	0.373211954612391	386	2961002			
SGTC_2010	4012422	159	µM	0.322797461516822	0.333087311465525	no	1116	0.373424317800715	415	952393			
SGTC_2123	5259487	200	µM	0.322723942563721	0.333117529193335	no	1117	0.373452159015513	413	2173474			
SGTC_1462	k081-0014	26.5	µM	0.322073465540548	0.333384935156985	no	1118	0.373698519775172	379	3270634			
SGTC_810	3825-7150	143	µM	0.322036916891709	0.333399962532058	no	1119	0.373712363691913	384	22330411		YGL099W	LSG1
SGTC_1471	k673-0312	37	µM	0.321858104870546	0.33347348689597	no	1120	0.373780096553256	407	24099884			
SGTC_401	neomycin	50	µM	0.321525506209686	0.333610262641493	no	1121	0.373906093187502	374	8378	Neomycin is an aminoglycoside antibiotic; inhibits initiation and elongation during protein synthesis.		
SGTC_1520	flindersine	88	µM	0.320153195689121	0.334174836571619	no	1122	0.374426100857502	411	68230	Flindersine is a natural alkaloid of the quinoline subtype.		
SGTC_2138	5575593	77.673	µM	0.318879976429795	0.334698979745307	no	1123	0.374908764396251	422	762213			
SGTC_3043	9092303	49.47	µM	0.318458249657162	0.334872662111547	no	1124	0.375068679664971	373	25236084			
SGTC_2012	4023501	200	µM	0.318015657756072	0.335054975485009	no	1125	0.375236529914337	424	3477460			
SGTC_2422	chlorphenesin carbamate	384.24	µM	0.31762269040229	0.335216879991618	no	1126	0.375385580162705	368	2724	A muscle relaxant with antifungal properties.		
SGTC_1423	4048-0112	5.59	µM	0.31744249180644	0.335291132950995	no	1127	0.375453934672735	418	X1423			
SGTC_1614	st002383	48.6	µM	0.315531063419308	0.336079155275444	no	1128	0.376179234756471	404	1947235			
SGTC_38	0929-0051	58.268	µM	0.31519793249871	0.336216568639944	no	1129	0.376305687623617	425	1379719			
SGTC_220	paclitaxel	373.376	µM	0.31437354347719	0.336556715405043	no	1130	0.376618673774399	417	4666	Paclitaxel is a potent anti-neoplastic and anti-mitotic taxane drug, which binds to the N-terminus of β-tubulin and and stabilizes microtubules arresting the cell cycle at the G2/M phase		
SGTC_2126	5251174	33.877	µM	0.314236915460568	0.336613101694366	no	1131	0.37667055357953	387	790722			
SGTC_3318	9139014	38.6185	µM	0.31412373522178	0.336659813883966	no	1132	0.376713531581789	435	16643984			
SGTC_1997	st073024	93.8	µM	0.313746414776093	0.336815561253793	no	1133	0.376856822744167	426	686268			
SGTC_24	0417-1663	219	µM	0.313129693036949	0.337070187058386	no	1134	0.377091065425539	410	4329390			
SGTC_3040	9091894	49.47	µM	0.313099788550532	0.337082535617829	no	1135	0.377102424870611	397	25236966			
SGTC_1834	st055981	52.8	µM	0.311403520626981	0.337783268246029	no	1136	0.377746938898943	426	471719		YDL150W	RPC53
SGTC_1969	st069479	40.1	µM	0.310498139271493	0.338157514074056	no	1137	0.378091087130015	439	3895485			
SGTC_2739	tacrine	100.86	µM	0.308758028419004	0.338877250246076	no	1138	0.378752799302139	411	1935	A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.		
SGTC_687	k029-0044	34.9	µM	0.308359764800529	0.339042060972903	no	1139	0.378904297133208	439	5829338			
SGTC_2827	7993847	71.43	µM	0.308003889230091	0.339189356608042	no	1140	0.379039686468279	410	2985692			
SGTC_1393	3470-5649	58.2	µM	0.307956239016141	0.339209080728812	no	1141	0.379057815647047	422	4108395			
SGTC_981	1488-1094	54.9	µM	0.30791060308975	0.339227971477304	no	1142	0.379075178711832	389	3449522			
SGTC_2994	9053520	71.4286	µM	0.306560288829163	0.339787109573791	no	1143	0.379589041981799	427	4647384			
SGTC_1742	st038235	28.8875	µM	0.306242973020605	0.339918554920485	no	1144	0.379709827694087	454	564103		YBR002C	RER2
SGTC_2986	9022445	71.43	µM	0.304143029806525	0.340788928327169	no	1145	0.380509462794034	448	6459286			
SGTC_1122	capsaicin	818.572	nM	0.303929989681148	0.340877275545608	no	1146	0.380590614709319	429	1548943	An isomer of capsaicen, an agonist at the TRPV1 receptor, a ligand-gated non-selective cation channel.		
SGTC_2156	5649887	115	µM	0.302590903752193	0.341432790866144	no	1147	0.381100823720338	416	54680440		YKL052C | YBR257W	ASK1 | POP4
SGTC_338	4055-0136	114	µM	0.300836393962734	0.342161163480149	no	1148	0.381769627398829	395	2900563			
SGTC_1675	st018485	24.5	µM	0.300668121596168	0.342231051515521	no	1149	0.381833789929225	396	3323024			
SGTC_1674	st016616	23.6	µM	0.298398607438022	0.343174168823912	no	1150	0.382699475892279	387	625830			
SGTC_1885	st057546	99.9	µM	0.297721539658128	0.343455720124418	no	1151	0.382957851128326	397	702008			
SGTC_1096	rimcazole	32.2	µM	0.297596277450968	0.343507818584935	no	1152	0.383005658041248	432	18528119	A dopamine reuptake inhibitor.		
SGTC_2504	purpurogallin	52.29	µM	0.293788448645999	0.345092967437994	no	1153	0.384459781213084	403	5281571	An antioxidant.		
SGTC_3207	9114163	49.47	µM	0.293214489333476	0.345332135866402	no	1154	0.384679104844454	439	849233			
SGTC_2688	kanamycin b	96.69	µM	0.291174746071648	0.346182594702614	no	1155	0.385458837949262	412	636396	Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate. Kanamycin interacts with the 30S subunit of prokaryotic ribosomes resulting in mistranslation and indirect inhibition of translocation during protein synthesis.		
SGTC_2061	5245884	80.95	µM	0.290912838410448	0.346291851873501	no	1156	0.385558991070089	427	573863			
SGTC_913	3487-1245	167	µM	0.289427665402909	0.346911647059577	no	1157	0.386127063281227	399	4016153			
SGTC_199	4063-0024	41.6	µM	0.289236427623437	0.346991484586991	no	1158	0.386200228673156	433	306215			
SGTC_922	1866-0035	480	µM	0.288257824135617	0.347400136068738	no	1159	0.386574694489925	424	3156169			
SGTC_1882	5615643	20	µM	0.286542277661078	0.348116952861627	no	1160	0.387231408687512	411	2253075			
SGTC_3315	9136395	68.55	µM	0.286392215001238	0.348179680280642	no	1161	0.387288868320339	461	16876844			
SGTC_2745	rifampicin	24.3	µM	0.285984567365524	0.348350101289416	no	1162	0.387444970802129	441	25141428	Inhibits bacterial DNA-dependent RNA polymerase.		
SGTC_2623	humulene	100	µM	0.285318407059332	0.348628661895153	no	1163	0.387700105952268	393	6187145	An anti-inflammatory.		
SGTC_217	ketoconazole	989	nM	0.284990783686259	0.348765690355955	no	1164	0.387825601412801	409	456201	Ketoconazole is an imidazole antifungal; acts by inhibiting lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YOR174W	MED4
SGTC_2082	5219693	150	µM	0.284854003212418	0.348822904622002	no	1165	0.387877998360565	423	2834649			
SGTC_2318	6029776	164	µM	0.283598599938599	0.349348191008932	no	1166	0.388359005082464	421	818325			
SGTC_1601	4'-hydroxyflavanone	55.5	µM	0.283200639970316	0.349514765901273	no	1167	0.388511518901176	428	165506			
SGTC_607	4491-0986	66.8	µM	0.282115045576522	0.349969312581375	no	1168	0.388927648454454	410	698981		YDR232W	HEM1
SGTC_1305	1181-0477	144	µM	0.282044548246296	0.349998837796713	no	1169	0.388954675871601	398	6252086			
SGTC_3154	9100113	49.47	µM	0.281598905954485	0.350185499668829	no	1170	0.389125539596806	403	25237525			
SGTC_509	pifithrin	175	µM	0.281373423955106	0.350279958924845	no	1171	0.389211999828991	430	4817	A p53 inhibitor.		
SGTC_1442	4112-3290	3	µM	0.281322037568858	0.350301487082628	no	1172	0.389231704514929	436	704353			
SGTC_1312	1218-2183	165	µM	0.280077600359501	0.350822986682328	no	1173	0.389708984781453	424	6744073			
SGTC_1111	tnp00062	510.699	nM	0.279951602678861	0.350875803543375	no	1174	0.389757318086901	400	676306			
SGTC_64	000l-0018	272.079	µM	0.279621280215817	0.351014284815254	no	1175	0.389884039435998	396	6811119			
SGTC_2778	tioconazole	65.09	nM	0.279077345871513	0.351242361832898	no	1176	0.390092734045545	432	5482	Tioconazole is a topically used antifungal; acts by inhibiting lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YGL116W	CDC20
SGTC_921	1561-0023	372	µM	0.278422519032298	0.351517008245823	no	1177	0.390344017479495	430	24050882			
SGTC_1322	1348-1070	12	µM	0.277817417372957	0.351770867935189	no	1178	0.390576260092333	432	6758089			
SGTC_178	4092-0806	87.505	µM	0.277497409048284	0.351905148493782	no	1179	0.390699097507535	415	2169044			
SGTC_1070	indatraline	8.81	µM	0.275963779010105	0.352548940087225	no	1180	0.391287943245116	442	10314472	A monamine transport inhibitor.	YGL099W	LSG1
SGTC_606	k015-0008	38.6	µM	0.275687829133727	0.352664824027006	no	1181	0.391393922224703	421	1970475			
SGTC_1963	st076565	50.3	µM	0.274987262866026	0.352959085156788	no	1182	0.391663011991003	432	4914280			
SGTC_3051	9093778	49.47	µM	0.274742380752439	0.353061964545691	no	1183	0.391757084236394	451	17217378			
SGTC_2863	9028737	58.44	µM	0.272673256368623	0.353931669151495	no	1184	0.392552197131173	447	6460917			
SGTC_2855	9016525	58.44	µM	0.272388793296167	0.354051295815688	no	1185	0.392661544351958	426	43811474			
SGTC_2261	9010538	184.68	µM	0.272114893317093	0.354166493944716	no	1186	0.392766839140951	421	6457250			
SGTC_941	3237-0776	460	µM	0.271634504466476	0.354368570353819	no	1187	0.392951532958432	455	760008			
SGTC_2489	cantharidin	73.42	µM	0.27063034727555	0.354791103216779	no	1188	0.393337676389821	440	2545	Cantharidin is a toxic blistering agent secreted by the Spanish fly of unknown mechanism. In Saccharomyces cerevisiae, cantharidin is thought to act by inhibiting GLC7 (encoding  type 1 serine/threonine protein phosphatase) as decreased expression confers hypersensitivity and overexpression confers resisitance (Hoon et al., Nat Chem Biol 4, 2008).	YER133W	GLC7
SGTC_2140	5586273	200	µM	0.270415720665079	0.354881437767644	no	1189	0.393420223563484	432	854421			
SGTC_953	1188-0045	9.7	µM	0.269036908437924	0.355461962723291	no	1190	0.393950640279125	428	6144426			
SGTC_1949	st076024	69.1	µM	0.26715662508552	0.356254163924366	no	1191	0.394674285434772	451	2921930			
SGTC_3261	9137475	49.47	µM	0.26602564417922	0.356730968176492	no	1192	0.395109729606509	438	17027690			
SGTC_3062	9077494	49.47	µM	0.265964491139924	0.356756755750843	no	1193	0.395133278158731	398	16459633			
SGTC_2645	abamectin	100	µM	0.26546074663969	0.356969204248998	no	1194	0.395327272512548	423	5702208	Abamectin is an avermectin, primarily used as an antihelmentic. Avermectins work by inhibiting neuronal activity by activating glutamate-gated chloride channels.		
SGTC_893	0958-0369	48.9	µM	0.264986559126913	0.357169227961225	no	1195	0.39550990803845	449	6819948			
SGTC_683	panaxydol	45	µM	0.264325409114249	0.3574481824789	no	1196	0.395764591339608	415	5283280	Panoxydol generates reactive oxygen species (ROS); known to Induce apoptosis.		
SGTC_2000	st075254	36.4	µM	0.263895489715505	0.357629616326976	no	1197	0.395930225589109	405	17234175			
SGTC_1514	1189-1591	158	µM	0.262039108422598	0.358413412156994	no	1198	0.396645645575056	450	767698		YMR146C	TIF34
SGTC_993	3909-8757	62.7	µM	0.261590783667058	0.358602792118484	no	1199	0.396818475116048	393	4288324		YLR208W	SEC13
SGTC_1224	0823-0416	294	µM	0.26156328264674	0.358614410147166	no	1200	0.396829077440882	431	3598164			
SGTC_523	1934-0222	13.7	µM	0.261560932463679	0.358615403007096	no	1201	0.396829983498229	458	1361595			
SGTC_1491	4138-0063	26.5	µM	0.261462157436535	0.358657132436002	no	1202	0.396868064371167	435	23883227			
SGTC_488	nitrendipine	139	µM	0.261365860419861	0.358697816605713	no	1203	0.396905190840088	420	4507	Dihydropyridine L-type calcium channel blocker.		
SGTC_2553	4-methylesculetin	85.09	µM	0.260840616059308	0.358919753362189	no	1204	0.397107710629761	408	5319502			
SGTC_1619	st003326	88.7	µM	0.259409726105872	0.359524603058484	no	1205	0.397659563079683	418	2849032			
SGTC_1761	st044296	37	µM	0.258843028519134	0.359764248509283	no	1206	0.397878178479191	409	1826700			
SGTC_3288	9119690	36.221	µM	0.258523063176541	0.35989958002975	no	1207	0.398001625945215	447	17595618		YKL019W	RAM2
SGTC_3322	9139058	2.11	µM	0.25715708651498	0.360477526532625	no	1208	0.398528755101505	401	4908926		YPR165W	RHO1
SGTC_2737	bleomycin	30.5	nM	0.254297694885831	0.361688370002798	no	1209	0.399632790249554	453	16211318	Bleomycin acts by induction of DNA strand breaks.		
SGTC_53	0973-0023	39.979	µM	0.253315965794198	0.362104415176925	no	1210	0.400012029726887	442	674768			
SGTC_141	0443-0274	32.331	µM	0.251354671988274	0.362936075902292	no	1211	0.400769954699224	427	1627241			
SGTC_79	0052-0007	94.094	µM	0.251254577566694	0.362978537000102	no	1212	0.400808645366507	454	2801472			
SGTC_1521	st012942	49.4	µM	0.251205596366833	0.362999315949916	no	1213	0.400827578997087	442	24207259			
SGTC_602	3130-1533	38.1	µM	0.250668625255849	0.363227137860906	no	1214	0.401035159874576	444	720941			
SGTC_2508	celastrol	40.54	µM	0.249367628927189	0.363779314964089	no	1215	0.401538211361883	395	122724	Celastrol is a natural product and antioxidant.		
SGTC_2693	st077581	40.7	µM	0.248496052809193	0.364149393217555	no	1216	0.401875311863041	452	25238761			
SGTC_898	1000-0849	28.3	µM	0.247310879233832	0.364652830736774	no	1217	0.402333819921651	454	6751807			
SGTC_2133	5320837	200	µM	0.246841463667016	0.364852293484825	no	1218	0.402515459899997	431	2841355			
SGTC_2457	5731572	11.68	µM	0.24435682492463	0.36590866733186	no	1219	0.403477238528141	456	2865357			
SGTC_1263	0774-1208	64.8	µM	0.243281467616739	0.366366184285277	no	1220	0.403893679945953	452	906585			
SGTC_1202	1988-0068	29.6	µM	0.241116126114743	0.367288017198509	no	1221	0.404732557304413	416	2850480			
SGTC_598	3937-0236	20.2	µM	0.239571940756305	0.367945878371245	no	1222	0.405331059695521	436	1379313			
SGTC_965	1291-5240	308	µM	0.239442696971986	0.368000957022143	no	1223	0.405381162651609	437	2834598			
SGTC_300	r073-0011	5.04	µM	0.238797969308303	0.368275755275967	no	1224	0.40563112247147	430	2735780			
SGTC_1658	st012944	20	µM	0.236427693468803	0.369286601597913	no	1225	0.406550404473188	451	24207260			
SGTC_2722	naftopidil	47.16	µM	0.23615697041092	0.369402113945145	no	1226	0.406655433924821	447	4418	An a1-adrenergic receptor antagonist or alpha blocker. 		
SGTC_3208	9114115	49.47	µM	0.235947584351237	0.369491463056114	no	1227	0.406736671740557	451	650895			
SGTC_1582	3',3',6'-trihydroxyflavone	74	µM	0.23582429624144	0.369544075791882	no	1228	0.406784507063973	442	688803			
SGTC_2640	pentamidine	10.38	µM	0.235648400542731	0.369619142846416	no	1229	0.406852756341683	438	4735	Thought to act by inhibiting tRNA aminoacylation and translation.		
SGTC_945	3381-0768	11.3	µM	0.235167446590828	0.369824425058632	no	1230	0.407039385687861	464	1126236		YIL048W	NEO1
SGTC_1511	0906-3109	28.5	µM	0.234561470214568	0.370083122534787	no	1231	0.407274558778204	418	2882180			
SGTC_490	phenamil	164	µM	0.23433277401134	0.370180770555817	no	1232	0.407363322074766	431	4755	Irreversibly blocks amiloride-sensitive Na+ channels.		
SGTC_754	3474-0146	171	µM	0.233102977033294	0.370706008932267	no	1233	0.407840721619752	404	24762078			
SGTC_492	tmb-8	126	µM	0.232405439464989	0.371004029941635	no	1234	0.408111562248071	451	5494	TMB-8 is a protein kinase C (PKC) inhibitor which also serves as an intracellular Ca2+ and Na+ channel-blocker resulting in reduced membrane K+ conductance.	YKL104C	GFA1
SGTC_98	0074-0023	107.663	µM	0.231632574048424	0.371334324937112	no	1235	0.408411702526935	450	3563821			
SGTC_3086	9117350	49.47	µM	0.227528319452915	0.373089919040454	no	1236	0.410006475441902	441	2679265			
SGTC_1555	citronellol	128	µM	0.227434204277567	0.373130207870576	no	1237	0.410043062951198	467	8842	A terpine precursor.		
SGTC_3249	9135183	49.47	µM	0.227300497861468	0.373187447306917	no	1238	0.410095043000706	432	4902779			
SGTC_2403	6032726	181.2	µM	0.227088877269178	0.373278047358819	no	1239	0.410177316393848	423	2881040			
SGTC_2142	5622915	118.518	µM	0.224724208847443	0.374290896369103	no	1240	0.411096915160282	439	5322196			
SGTC_761	k216-0224	480	µM	0.224336787807296	0.374456921842997	no	1241	0.411247626530054	474	1340404			
SGTC_1207	2099-0101	141	µM	0.223959747050477	0.37461852130216	no	1242	0.411394312424501	450	5837381			
SGTC_3149	9097855	49.47	µM	0.223039525626274	0.375013020110115	no	1243	0.41175237211621	478	25236625		YMR079W	SEC14
SGTC_1838	st055369	84.5	µM	0.223031031591681	0.375016662111519	no	1244	0.411755677502026	401	676036			
SGTC_937	3122-0005	46.7	µM	0.221693871336506	0.375590137318639	no	1245	0.41227610068694	464	759535			
SGTC_2876	9059903	25.97	µM	0.220162682237095	0.376247164415329	no	1246	0.412872229411066	450	6916095			
SGTC_1820	st053765	18.6	µM	0.220082967964751	0.376281379331559	no	1247	0.412903269609342	432	3690829			
SGTC_2219	9098279	200	µM	0.220071168251586	0.376286444080587	no	1248	0.412907864384083	443	902349			
SGTC_1073	triclabendazole	3.09	µM	0.219588919969673	0.376493456017539	no	1249	0.413095660694936	421	50248	An antihelmetic and likely tubulin inhibitor.		
SGTC_43	0570-0105	72.5	µM	0.218595971799405	0.376919804970558	no	1250	0.413482395478903	465	1114046		YDL195W	SEC31
SGTC_3308	9128332	17.569	µM	0.218544162804765	0.376942054678539	no	1251	0.413502576423157	454	17332805		YDL196W	YDL196W
SGTC_354	2783-3500	4.88	µM	0.218391870136857	0.377007460116092	no	1252	0.413561899681564	432	6740761			
SGTC_1435	4092-0789	56.7	µM	0.218162134832371	0.377106131675246	no	1253	0.413651393256647	461	2248285			
SGTC_2879	9041815	71.43	µM	0.218136962476867	0.377116943716833	no	1254	0.413661199440995	437	4942971			
SGTC_1633	st005664	67.9	µM	0.217840175806902	0.3772444269244	no	1255	0.413776820204237	432	2063822			
SGTC_642	0335-0876	158	µM	0.217509583578074	0.377386446889958	no	1256	0.413905619579688	465	6812350			
SGTC_2650	prasterone	100	µM	0.216103473222754	0.377990686503161	no	1257	0.414453546220605	451	16759247	A steroid and weak partial agonist of the androgen receptor.		
SGTC_2528	xanthyletin	44.79	µM	0.215854904082045	0.37809753377253	no	1258	0.414550424854528	442	65188	An natural product with antifungal activity of unknown mechanism.		
SGTC_2359	9039622	200	µM	0.215052028297481	0.378442713021143	no	1259	0.414863377333896	450	6463596			
SGTC_2830	7992007	71.43	µM	0.214914831652035	0.378501707493959	no	1260	0.414916860544992	463	1952075			
SGTC_2458	5808907	16.39	µM	0.213812919754309	0.378975631529239	no	1261	0.415346474712845	468	2731747			
SGTC_2790	5423970	71.43	µM	0.213068441848063	0.379295928953557	no	1262	0.41563678960194	430	1376240		YKL165C | YIL048W	MCD4 | NEO1
SGTC_1225	1216-0074	20.6	µM	0.213058156713437	0.379300354517477	no	1263	0.41564080069222	442	4241466			
SGTC_2372	9071633	200	µM	0.212629725169141	0.379484717261815	no	1264	0.415807892123713	457	21321366			
SGTC_542	3381-0244	89.3	µM	0.211460990234174	0.379987786743254	no	1265	0.416263784600974	479	1112843			
SGTC_2576	guaiol	23.12	µM	0.210523100974385	0.380391638129991	no	1266	0.416629711832341	421	227829			
SGTC_1706	st031321	9.9705	µM	0.208258878888921	0.381367139813222	no	1267	0.4175134187778	438	6103185			
SGTC_2951	9072950	58.06	µM	0.208164028259731	0.381408021098917	no	1268	0.417550447311319	475	16488155			
SGTC_1982	st072467	71.9	µM	0.207558686283787	0.381668958883315	no	1269	0.417786782674819	436	3163533			
SGTC_1143	3454-2408	5.08	µM	0.206790376829256	0.382000222616927	no	1270	0.418086785948711	442	X1143			
SGTC_368	fentichlor	4.58	µM	0.206588855124202	0.38208712488011	no	1271	0.418165482415479	452	7329	A pesticide.		
SGTC_1016	4226-1401	38	µM	0.205294499553683	0.3826454316515	no	1272	0.418671020630494	478	2901613			
SGTC_422	cantharidin	155	µM	0.204331109255746	0.383061138453745	no	1273	0.419047380547198	462	2545	Cantharidin is a toxic blistering agent secreted by the Spanish fly of unknown mechanism. In Saccharomyces cerevisiae, cantharidin is thought to act by inhibiting GLC7 (encoding  type 1 serine/threonine protein phosphatase) as decreased expression confers hypersensitivity and overexpression confers resisitance (Hoon et al., Nat Chem Biol 4, 2008).	YER133W	GLC7
SGTC_2116	5511452	16.8835	µM	0.204046569296073	0.383183944386122	no	1274	0.419158553666758	466	870744			
SGTC_3262	9137218	49.47	µM	0.20394812208235	0.383226436413995	no	1275	0.419197019658175	461	17650664			
SGTC_2070	5230947	200	µM	0.203856293317714	0.383266073037087	no	1276	0.419232900338572	468	2835538			
SGTC_257	daunorubicin	18.5	µM	0.202449756121769	0.383873337942072	no	1277	0.4197825669236	457	30323	Daunorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.	YIL143C	SSL2
SGTC_481	bay k-8644	50	µM	0.202378064073393	0.383904298253371	no	1278	0.41981058796233	448	2303	A calcium channel antagonist.		
SGTC_2767	sibutramine 	71.45	µM	0.202354228207882	0.383914591969355	no	1279	0.419819904367461	468	64765	A serotonin-norepinephrine reuptake inhibitor. 		
SGTC_3305	9127027	53.8275	µM	0.199819640234879	0.385009640815477	no	1280	0.420810820201015	440	41905295			
SGTC_3150	9097574	49.47	µM	0.199080658563918	0.385329085233729	no	1281	0.421099825314609	464	17217476			
SGTC_2100	5377183	190	µM	0.197108584646653	0.386181946855699	no	1282	0.421871282819717	465	2844202			
SGTC_497	capsazepine	133	µM	0.196059635462508	0.386635809736899	no	1283	0.422281744646101	435	2733484	A calcium channel blocker.		
SGTC_1342	1486-1464	234	µM	0.195529921351907	0.386865067211373	no	1284	0.422489057931458	460	3253938			
SGTC_3054	9094397	49.47	µM	0.194675273129561	0.387235037661717	no	1285	0.422823585359792	449	2598354			
SGTC_1668	st014914	51.6	µM	0.193870300362271	0.387583597704762	no	1286	0.423138719670255	476	2839556			
SGTC_808	0711-0032	135	µM	0.193816123644011	0.387607059941758	no	1287	0.423159930780976	471	4252555			
SGTC_1930	st074634	34.3	µM	0.193611136064098	0.387695837345292	no	1288	0.423240188935546	427	684253		YOR116C	RPO31
SGTC_699	0375-0592	111	µM	0.191936170102065	0.388421462504505	no	1289	0.423896102249245	467	762578			
SGTC_385	1494-0393	12.4	µM	0.19181376985603	0.388474503781901	no	1290	0.423944042230802	459	3090647			
SGTC_2854	9024559	71.43	µM	0.189431168195989	0.389507400401806	no	1291	0.424877448994797	448	3163529			
SGTC_2263	7948595	193.29	µM	0.189090414918134	0.389655186504237	no	1292	0.425010976879282	454	2971371			
SGTC_3144	9087057	49.47	µM	0.188611780336906	0.389862799240656	no	1293	0.425198549581775	488	17249618			
SGTC_2436	5633522	8.09	µM	0.188102850576191	0.390083587299389	no	1294	0.425398013274738	447	5724242			
SGTC_701	4424-0219	185	µM	0.187082793387143	0.390526223534159	no	1295	0.425797859431062	446	2911779			
SGTC_3216	9129716	49.47	µM	0.185867530519732	0.391053751127904	no	1296	0.426274322682629	429	8056934			
SGTC_3061	glucosamine 	200	µM	0.185857892361106	0.391057935712365	no	1297	0.426278101908034	485	91431	and experimental redox chemotherapeutic		
SGTC_1830	st055982	50.3	µM	0.184962758728851	0.391446629419537	no	1298	0.426629122875152	477	455313	An antimicrobial agent.		
SGTC_185	k048-0037	25.491	µM	0.184930406633294	0.391460679696169	no	1299	0.426641810633817	469	6827589			
SGTC_2056	5235370	200	µM	0.183744411186408	0.391975846382695	no	1300	0.427106983462219	438	5511916			
SGTC_97	0535-0701	19.132	µM	0.183612144498863	0.392033311473463	no	1301	0.427158867586655	445	2832013		YGL099W	LSG1
SGTC_1106	tegaserod maleate	11.7	µM	0.183130566160197	0.392242559728597	no	1302	0.427347786491032	457	6918369	Tegaserod is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation.		
SGTC_2181	6316240	54.2555	µM	0.182146213564928	0.392670362860553	no	1303	0.427733991059203	435	12779990			
SGTC_242	5hr heat shock (37°C) + 5-fluorouracil	4.569	µM	0.181885029501105	0.392783896176187	no	1304	0.427836476628872	443	3385	5-fluorouracil (5-FU) is a potent FDA-approved antitumor agent. 5-FU is a pyrimidine analog that inhibits thymidylate synthase and is metabolized into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition to being incorporated in DNA and RNA, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex.		
SGTC_555	4296-0685	37	µM	0.18177710468097	0.392830812356037	no	1305	0.427878826487068	471	2908540		YHR072W	ERG7
SGTC_1664	st014217	9.02	µM	0.179054404252933	0.394014915418956	no	1306	0.428947491735027	476	3982782			
SGTC_2747	doxorubicin	7.63	µM	0.17702361180567	0.39489874654742	no	1307	0.429744921466831	485	31703	Doxorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.		
SGTC_329	k048-0121	21.3	µM	0.175234313904813	0.395677924268166	no	1308	0.430447761431407	449	6832902			
SGTC_347	4534-1311	26.2	µM	0.175073557866682	0.395747948463163	no	1309	0.430510917563	454	2862016			
SGTC_2383	9036125	200	µM	0.174927443668976	0.395811597695207	no	1310	0.430568322905295	484	79580			
SGTC_1893	st059353	36.1	µM	0.174748001204179	0.395889768952032	no	1311	0.43063882426365	480	3112488			
SGTC_2232	chlorophetanol	41.5365	µM	0.173531315200318	0.396419909164336	no	1312	0.431116907641568	474	15907	An antifungal of unknown mechanism.	YFR051C	RET2
SGTC_3266	9136860	49.47	µM	0.173512978854205	0.396427900231971	no	1313	0.431124113480899	473	4871271		YPR165W	RHO1
SGTC_1515	3460-0031	42.1	µM	0.17319003947079	0.39656864589318	no	1314	0.431251026343267	458	2876596			
SGTC_1095	3-[3,5-dibromo-4-hydroxybenzoyl]-2-ethylbenzofuran	15.5	µM	0.17265157397109	0.396803353591392	no	1315	0.431462655203143	469	2333	A French combination drug.		
SGTC_2502	avocadyne acetate	18.59	µM	0.172339614188583	0.396939348518531	no	1316	0.431585271307913	450	3952079			
SGTC_77	0828-0286	12.516	µM	0.172061295235335	0.397060688731218	no	1317	0.431694670415787	431	745345			
SGTC_229	benomyl	22.8748	µM	0.171682511580198	0.397225845089482	no	1318	0.431843567699434	449	28780	Benomyl is a fungal microtubule inhibitor often used in molecular biology to study the cell cycle in yeast.	YIL142W | YJL014W | YDR212W | YDR187C	CCT2 | CCT3 | TCP1 | YDR187C
SGTC_3128	9127691	49.47	µM	0.170928221045896	0.39755478393918	no	1319	0.432140103008424	481	41316314			
SGTC_2978	9011784	42.97	µM	0.169719296921247	0.398082136003643	no	1320	0.432615448745173	449	2994934			
SGTC_1475	4092-1048	11.7	µM	0.169158487037066	0.398326833550508	no	1321	0.432835990853851	459	2881759			
SGTC_2223	6903751	107.57	µM	0.168616746469751	0.398563248575419	no	1322	0.433049053699061	479	5598863			
SGTC_1419	3993-2473	62.6	µM	0.168273293997626	0.398713150169342	no	1323	0.433184141283021	475	704026			
SGTC_1067	clotrimazole	1.36	µM	0.16809221555472	0.398792188802451	no	1324	0.433255366652622	465	2812	Clotrimazole, an imidazole antifungal; inhibits lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YJL195C	YJL195C
SGTC_2062	5245942	200	µM	0.1678835766334	0.398883262409843	no	1325	0.433337435344883	460	1376160			
SGTC_2937	9044753	11.33	µM	0.167424845789803	0.399083523753047	no	1326	0.433517888484846	467	6465530		YGL099W	LSG1
SGTC_59	0330-0160	1.33	µM	0.165646826763953	0.399859977802675	no	1327	0.434217446943775	471	4293482			
SGTC_230	MPP+	141.667	µM	0.164690513849522	0.400277759985138	no	1328	0.434593791938078	464	39484	MPP+ (1-methyl-4-phenylpyridinium) is a toxic positively charged molecule and acts by interfering with oxidative phosphorylation in mitochondria, causing depletion of ATP and cell death.		
SGTC_283	0987-0079	11.7	µM	0.164662080501882	0.400290183344687	no	1329	0.434604982435731	480	411556			
SGTC_56	0957-0365	83.25	µM	0.164357799713313	0.400423138817717	no	1330	0.434724741344057	469	6752360			
SGTC_3337	9144342	33.5465	µM	0.163988331748596	0.400584593334905	no	1331	0.43487016468787	474	17682949			
SGTC_2695	st077686	51.995	µM	0.162138421879307	0.401393243938387	no	1332	0.43559842509996	455	2876092			
SGTC_1510	1123-0200	71.5	µM	0.160937377687111	0.401918482494702	no	1333	0.436071361434095	473	5378812		YNL149C | YNL150W	PGA2 | YNL150W
SGTC_2610	ononetin	44.17	µM	0.159944544662545	0.40235280033141	no	1334	0.436462379308361	460	259632			
SGTC_1064	honokiol	6.76	µM	0.158331253379539	0.403058796447257	no	1335	0.43709789105344	479	72303	Inhibits phosporylation of AKT, SRC Kinases and induces apoptosis.		
SGTC_3006	9075424	71.4286	µM	0.158155507251844	0.403135724251594	no	1336	0.437167131243777	479	7465181			
SGTC_1913	st060213	96.1	µM	0.15761524113395	0.403372233645431	no	1337	0.437379996504829	464	688959			
SGTC_2872	9044037	25.97	µM	0.156839371197988	0.40371194386459	no	1338	0.437685721542187	458	6465195			
SGTC_3189	9110682	49.47	µM	0.156591604878282	0.40382044224882	no	1339	0.437783359627425	471	17122418			
SGTC_1285	0929-0069	65.5	µM	0.156251454233803	0.403969408346061	no	1340	0.437917410075345	452	1206237			
SGTC_2375	9072683	200	µM	0.155934429588988	0.404108259147829	no	1341	0.43804235318041	482	16798029			
SGTC_3126	9127922	49.47	µM	0.155610294188923	0.404250236817334	no	1342	0.438170105102935	492	45595682			
SGTC_594	1487-1584	10.8	µM	0.155007329654454	0.404514380660968	no	1343	0.43840776946106	468	5013332			
SGTC_608	k048-0125	159	µM	0.154744744059816	0.404629426525231	no	1344	0.438511277085314	483	6817652		YLR060W | YFL022C	FRS1 | FRS2
SGTC_2465	5809242	33.21	µM	0.153622561929387	0.40512117772244	no	1345	0.438953673132679	487	2731748			
SGTC_927	2425-1185	123	µM	0.153576503349715	0.405141364249488	no	1346	0.438971832365304	491	730375			
SGTC_2020	4017018	200	µM	0.153053056864243	0.405370797785569	no	1347	0.439178217404266	473	21127491	Used for adrenal and myocardial imaging when labeled with iodine radioisotope.		
SGTC_760	0568-0725	82.9	µM	0.152973212486749	0.405405797495606	no	1348	0.439209699985484	497	3916171			
SGTC_150	3970-0969	77.2	µM	0.152939439226212	0.405420602201213	no	1349	0.439223016873814	455	6615640			
SGTC_155	k072-0202	43.6	µM	0.152293907887118	0.405703600613529	no	1350	0.439477564838486	491	5857737			
SGTC_1606	st000094	49.2	µM	0.151672029842434	0.405976276132868	no	1351	0.439722809429574	476	1242210			
SGTC_1676	st018489	23.4	µM	0.151307767728426	0.406136015719553	no	1352	0.439866471034546	495	3696235			
SGTC_859	0439-0102	54.6	µM	0.149798025703243	0.406798248051886	no	1353	0.440461983521591	462	610143			
SGTC_204	PMA1.184	62.41	µM	0.148705078338707	0.407277824297264	no	1354	0.44089317693109	465	2252213		YGL008C	PMA1
SGTC_2749	bexarotene	57.39	µM	0.148217693776172	0.407491729469123	no	1355	0.441085484215656	472	82146	An retinoic acid receptor inhibitor.		
SGTC_2812	7970281	58.44	µM	0.148203687417195	0.407497877040761	no	1356	0.441091010909075	466	2233435			
SGTC_148	3253-0744	288.01	µM	0.148096175025381	0.40754506637491	no	1357	0.441133434024079	484	6893655			
SGTC_1397	3532-0190	20.1	µM	0.146414632428421	0.408283303145002	no	1358	0.441797038390467	458	5322280			
SGTC_544	k015-0020	52.4	µM	0.14471981470412	0.40902769753707	no	1359	0.44246604699251	478	3008304			
SGTC_977	1348-1378	135	µM	0.144149750065594	0.409278154067984	no	1360	0.442691110024619	501	X977			
SGTC_1038	k292-0204	154	µM	0.143396275032262	0.409609248328694	no	1361	0.44298861233392	488	4454212			
SGTC_1973	st070275	50.2	µM	0.143124262987614	0.409728792529637	no	1362	0.443096021557449	494	17118334			
SGTC_2649	anisomycin	9.56	µM	0.142340968166772	0.410073082780464	no	1363	0.443405344017981	481	6610309	Antibiotic isolated from Streptomyces griseolus that inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in eukaryote ribosomes.		
SGTC_3269	9137823	49.47	µM	0.141719621201017	0.41034623962386	no	1364	0.443650737947689	500	17682936			
SGTC_1757	st041620	31.8375	µM	0.141050511197466	0.410640442718397	no	1365	0.443915019509407	472	5289815			
SGTC_2661	dactinomycin	12.96	µM	0.140925412037766	0.410695453548313	no	1366	0.443964433290952	482	45006140	An Actinomycin D Classic transcription inhibitor.		
SGTC_910	3454-3003	490	µM	0.140636055387721	0.410822701335777	no	1367	0.444078731610245	497	820824			
SGTC_1536	cytidine-2',3'-monophosphoric acid;  3'-cytidylic acid	61.9	µM	0.139648476017834	0.411257070891569	no	1368	0.444468868769523	479	66535	A nucleotide analog.		
SGTC_110	0850-0284	111.64	µM	0.139085819369603	0.411504594293884	no	1369	0.444691166905104	479	3906265			
SGTC_3118	9124250	49.47	µM	0.13739489450648	0.41224867604927	no	1370	0.445359333186167	491	1504786			
SGTC_1247	0448-0043	5.84	µM	0.136730937312665	0.412540933016161	no	1371	0.44562173737161	472	3089013		YGL099W	LSG1
SGTC_47	0149-0135	24.25	µM	0.136211643470629	0.412769546683797	no	1372	0.445826985399878	504	5239155			
SGTC_1118	chelidonine	707.474	nM	0.135981054717241	0.412871070455772	no	1373	0.445918128991432	494	10147	Benzophenanthridine derived from scoulerine from Chelidonium majus; putative GST and MDR inhibitor.		
SGTC_3278	9139605	49.47	µM	0.135174305361377	0.413226312428313	no	1374	0.446237030982968	470	7958859			
SGTC_2435	5706476	10.6	µM	0.135136348875237	0.413243027843926	no	1375	0.446252035756524	483	5725375			
SGTC_1364	1653-0028	37.6	µM	0.135095911574942	0.413260835942528	no	1376	0.446268021318143	504	5718652			
SGTC_151	3013-0144	2.285	µM	0.134163043318741	0.413671709327581	no	1377	0.446636824407884	496	906558		YHR107C	CDC12
SGTC_1872	amphotericin b	148	nM	0.134118901213095	0.413691153664719	no	1378	0.446654276833975	495	16667679	Amphotericin b is a polyene antifungal that binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.	YNL221C	POP1
SGTC_340	k038-0059	454	µM	0.133601789525302	0.413918954061647	no	1379	0.446858734520363	479	23733424			
SGTC_1405	3909-7894	12	µM	0.133198229619629	0.414096752239467	no	1380	0.447018305465537	488	7104060			
SGTC_2235	salicylic acid	500	µM	0.132435256790943	0.414432946648606	no	1381	0.447320014689448	480	338	A COX inhibitor and kinase inhibitor.		
SGTC_1976	st070609	63.5	µM	0.131662048695151	0.414773715065813	no	1382	0.447625802440342	502	682556			
SGTC_1188	1403-0014	4.57	µM	0.131521445361345	0.414835688693513	no	1383	0.447681411490599	490	9614867			
SGTC_383	2324-0395	7.37	µM	0.13108434020832	0.415028364739772	no	1384	0.447854294483674	495	3146421			
SGTC_553	k007-0256	45.7	µM	0.130469311433165	0.415299504160565	no	1385	0.448097566254729	469	6287000			
SGTC_958	1222-0007	33	µM	0.129899399350563	0.415550789609262	no	1386	0.448323009755845	482	7312461			
SGTC_1694	st024011	44.9	µM	0.129628835414239	0.415670098669022	no	1387	0.448430044183294	492	2787533			
SGTC_2516	gossypol	71.55	µM	0.128558971912888	0.416141946415623	no	1388	0.44885331624848	479	3503	Gossypol is a phenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.		
SGTC_2918	7977171	22.06	µM	0.127895925239951	0.416434434235558	no	1389	0.449115667876015	488	2236483			
SGTC_2086	5274770	176.623	µM	0.127496476630399	0.416610664168635	no	1390	0.44927373083376	485	689278			
SGTC_1290	0986-0249	10.2	µM	0.12665743537887	0.416980889439356	no	1391	0.449605768041558	491	53329			
SGTC_679	0422-0091	41.4	µM	0.125878073686235	0.417324847196871	no	1392	0.449914219631683	499	627384		YHR062C	RPP1
SGTC_1206	3978-0017	132	µM	0.125765324926573	0.417374612150575	no	1393	0.449958845240984	489	3873677			
SGTC_3316	9136639	10.545	µM	0.1238261265657	0.418230740401926	no	1394	0.450726472500823	498	4903665			
SGTC_2714	st079313	56.9	µM	0.12335654448441	0.418438112594388	no	1395	0.450912383332474	491	2939799			
SGTC_668	1682-0499	62.6	µM	0.122027796737122	0.41902502368206	no	1396	0.451438502080659	489	682214			
SGTC_1572	epiandrosterone	68.9	µM	0.121785989043582	0.419131850147965	no	1397	0.451534255235341	480	441302	A steroid.		
SGTC_2417	cerulenin	830	nM	0.121549652785447	0.419236265189383	no	1398	0.451627844487424	509	5282054	Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis.	YKL182W	FAS1
SGTC_1040	k898-0338	155	µM	0.120994049257162	0.419481757175567	no	1399	0.451847874285826	492	20969351			
SGTC_3295	9122362	53.5725	µM	0.120675598775441	0.419622477836669	no	1400	0.451973993540476	488	4730473			
SGTC_2887	9044784	58.44	µM	0.120499907400669	0.419700118818167	no	1401	0.452043576497413	510	6465546			
SGTC_1230	0170-0365	3.77	µM	0.119533151283166	0.42012740049586	no	1402	0.452426488690922	496	4018932		YCR093W | YMR134W | YIL048W | YNL267W	CDC39 | ERG29 | NEO1 | PIK1
SGTC_3257	9139206	32.98	µM	0.118576307499867	0.420550393889825	no	1403	0.45280551838753	502	4910041			
SGTC_1786	berberine	21.6	µM	0.116957805479298	0.421266096183983	no	1404	0.453446745139218	497	12456	Berberine is a quaternary ammonium salt and isoquinoline alkaloid.		
SGTC_2065	5221596	34.26	µM	0.116835440664559	0.421320216568419	no	1405	0.45349522923991	470	788581			
SGTC_586	0957-0265	8.15	µM	0.115012705261338	0.422126564453805	no	1406	0.45421752576592	511	6752309		YPR165W | YPR107C	RHO1 | YTH1
SGTC_3106	9121286	49.47	µM	0.113238357611386	0.422911820095683	no	1407	0.454920793125646	449	15943471			
SGTC_839	0122-0028	230	µM	0.11294465636306	0.423041830215932	no	1408	0.455037216078731	506	759448			
SGTC_1709	st033179	39.1045	µM	0.112918985260506	0.423053194213162	no	1409	0.455047392268079	499	573381			
SGTC_1	0258-0098	57.368	µM	0.112885855168795	0.423067860225222	no	1410	0.455060525292066	465	6790032		YDR047W	HEM12
SGTC_201	4262-0159	12.803	µM	0.112649498658741	0.423172493496498	no	1411	0.455154220260676	495	1341029			
SGTC_2534	helenine	20.12	µM	0.111582643697127	0.423644849592338	no	1412	0.455577167196652	491	72724	Natural product isolated from Penicillium funiculosum with antiviral properties.	YLR033W	RSC58
SGTC_1689	st020265	53.493	µM	0.111557167138837	0.423656130827568	no	1413	0.455587267811434	510	5758320		YPR016C	TIF6
SGTC_3090	9117696	49.47	µM	0.111506544192806	0.423678547281414	no	1414	0.455607338224456	497	7923821			
SGTC_2245	6637752	200	µM	0.111458286523536	0.423699916592006	no	1415	0.45562647098478	482	681890			
SGTC_2296	7971656	126.45	µM	0.109743312669292	0.42445948119044	no	1416	0.456306474652224	486	666570			
SGTC_2265	7929201	200	µM	0.109597450734336	0.42452409665755	no	1417	0.456364316249502	505	1265108			
SGTC_1637	st007924	17.4	µM	0.109035111101807	0.424773226802119	no	1418	0.456587320855254	501	683336			
SGTC_558	k064-0027	21.3	µM	0.108873515543476	0.424844823130643	no	1419	0.456651406642061	480	5088526			
SGTC_44	0929-0055	61.211	µM	0.108786442410154	0.4248834026736	no	1420	0.456685938691524	504	1379590			
SGTC_361	000s-0510	1.45	µM	0.106889443671521	0.425724084954196	no	1421	0.457438343969778	478	660			
SGTC_1722	st034304	3.6505	µM	0.106558061151102	0.425870976645922	no	1422	0.457569795716809	491	4036148		YLR033W	RSC58
SGTC_2408	sulbentine	18.36	µM	0.105967363881198	0.42613284009947	no	1423	0.457804123102778	450	67686	An antifungal agent of unknown mechanism.	YDL205C	HEM3
SGTC_694	1315-0438	43.2	µM	0.105507020305898	0.426336938727723	no	1424	0.457986749842219	501	6793154			
SGTC_63	0099-0242	26.702	µM	0.105234031639893	0.426457980720913	no	1425	0.4580950536451	495	3898502		YLR359W	ADE13
SGTC_2205	7238770	200	µM	0.104755040029024	0.426670380262348	no	1426	0.458285093272272	493	279867			
SGTC_979	1426-2828	121	µM	0.104690411358159	0.426699040222815	no	1427	0.45831073538878	503	747872			
SGTC_1505	k297-0037	20.6	µM	0.101759292559152	0.427999266429535	no	1428	0.459473868847052	460	4089396			
SGTC_911	3456-4043	236	µM	0.101676670085175	0.428035928649677	no	1429	0.459506660366162	482	914281			
SGTC_224	benfluorex 	43.875	µM	0.101232127421596	0.428233197027174	no	1430	0.459683096858093	515	2318	Inhibits enzymes in fatty acid oxidation, ketogenisis and gluconeogenesis.		
SGTC_136	0097-0015	404.482	µM	0.101025231521258	0.428325014398603	no	1431	0.459765215391264	486	4861337			
SGTC_1759	st043059	70	µM	0.100556676954867	0.428532966391785	no	1432	0.459951194549479	497	669426			
SGTC_1213	1315-0166	115	µM	0.0996871944565059	0.42891890913582	no	1433	0.460296333620358	449	768401			
SGTC_1101	ebselen	5.29	µM	0.0991473462893584	0.429158569212867	no	1434	0.460510640174511	505	3194	A potent scavenger of hydrogen peroxide and  hydroperoxides.		
SGTC_285	1486-1325	46	µM	0.0983190051698496	0.429526353540049	no	1435	0.460839493676246	488	22310230			
SGTC_1385	3091-4834	14.1	µM	0.0983099416051038	0.429530378111245	no	1436	0.460843092082721	483	4072814			
SGTC_3183	9108214	49.47	µM	0.0979530195546148	0.429688871042483	no	1437	0.460984799427657	514	4974831			
SGTC_715	0868-0130	184	µM	0.0979285215056332	0.429699749933358	no	1438	0.460994525972703	482	2876258			
SGTC_697	0508-1955	564	µM	0.0975663048771713	0.429860606321631	no	1439	0.461138340812436	510	6243113			
SGTC_2405	ticlatone	3.52	µM	0.0966711555172049	0.430258182115018	no	1440	0.461493773539573	421	6258	An FDA approved topical antifungal of unknown mechanism.	YOR282W	YOR282W
SGTC_177	1327-0068	8.361	µM	0.0964078011598037	0.430375163022902	no	1441	0.46159834827845	496	15389900		YOR207C | YLR033W	RET1 | RSC58
SGTC_1436	4092-1007	8.32	µM	0.0962133089706775	0.430461559566171	no	1442	0.461675580411932	490	2881121			
SGTC_84	0443-0269	128.823	µM	0.0945615492578008	0.43119543144314	no	1443	0.462331546088049	518	6150058			
SGTC_3033	9090887	49.47	µM	0.0930965410098114	0.431846529119028	no	1444	0.46291343268885	479	19325384			
SGTC_1544	7-methoxy-4-methylcoumarin	105	µM	0.0927538459192708	0.431998860838026	no	1445	0.463049559245837	496	390807			
SGTC_226	1,3-diallylurea	8.28947	mM	0.0927388667128281	0.432005519490054	no	1446	0.463055509438061	483	74537		YKL182W	FAS1
SGTC_1984	st072354	53.1	µM	0.0921328029447941	0.432274946988049	no	1447	0.463296263149847	497	5762938			
SGTC_667	1498-1044	59	µM	0.0915562471060234	0.432531285882979	no	1448	0.463525307565124	512	6739982			
SGTC_1671	st016596	74.5	µM	0.0912874048537987	0.43265082387487	no	1449	0.463632112835491	516	2829167			
SGTC_371	0195-0006	7.36	µM	0.0890641841082661	0.433639591785855	no	1450	0.464515450589941	502	3928593			
SGTC_1725	st036284	20.55	µM	0.088408573455544	0.433931251415122	no	1451	0.464775973674109	462	707914			
SGTC_486	niguldipine	82	µM	0.0876595972211237	0.434264490337464	no	1452	0.46507361635117	486	1236	A calcium channel blocker.		
SGTC_3264	9137442	49.47	µM	0.0873212505505742	0.434415044866215	no	1453	0.465208081519947	467	17015726			
SGTC_2376	9072922	81.32	µM	0.0868137515573571	0.434640885137279	no	1454	0.465409778366074	503	17087968			
SGTC_1172	0370-0043	85	µM	0.0866368655314278	0.434719605557085	no	1455	0.465480080800673	500	376585			
SGTC_1698	5-fluorocytosine	1.055	µM	0.0863300897354446	0.43485613756664	no	1456	0.465602009804743	520	3366	The mechanism of 5-fluorocytosine (5-FC) is identical to 5-fluorouracil (5-FU) and acts by inhibiting thymidylate synthetase and through metabolism into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex. The specificity of 5-FC for fungi is due to the requirement for the fungal specific cytosine permease in addition to cytosine deaminase that acts to convert 5-FC to 5-FU.		
SGTC_3007	9078383	71.4286	µM	0.0862746226914361	0.434880824264953	no	1457	0.46562405570072	485	6496995			
SGTC_710	3448-4187	58	µM	0.0856342444920638	0.43516585553151	no	1458	0.465878587634802	488	3946412			
SGTC_2441	5730946	39.09	µM	0.0853336027980865	0.435299682277925	no	1459	0.465998088890909	500	1774275			
SGTC_2544	sphondin	68.51	µM	0.0843613424038199	0.435732522028426	no	1460	0.466384570987399	518	108104	Sphondin is a coumarin of the psoralen class.	YOR116C	RPO31
SGTC_612	0302-0167	22.4	µM	0.0830741137450662	0.436305700593115	no	1461	0.466896304460467	497	235821			
SGTC_1977	st070720	65.3	µM	0.0827827685817779	0.436435449690469	no	1462	0.467012135386367	483	682188			
SGTC_2240	6690706	185.951	µM	0.0792907317292631	0.437991139049735	no	1463	0.468400689050383	505	805876			
SGTC_1998	st075797	76.8	µM	0.0786418451359248	0.4382803219597	no	1464	0.468658751490816	518	24208315			
SGTC_747	3448-8087	38.7	µM	0.0781922513636134	0.438480707335891	no	1465	0.468837562831712	508	5168703			
SGTC_3276	9139060	49.47	µM	0.0781242352523109	0.438511023708093	no	1466	0.468864614582278	518	4870619			
SGTC_1758	st042942	75.2445	µM	0.0775865750885873	0.438750684107472	no	1467	0.469078460857627	519	669317			
SGTC_1641	st009299	47.1	µM	0.0771353823761582	0.438951819235911	no	1468	0.469257922886345	502	4046054			
SGTC_1718	roemerine	11.9335	µM	0.075810924771149	0.439542333983703	no	1469	0.469784762214779	503	235224	An aporphine alkaloid with mutagenic activity.		
SGTC_1049	3226-0134	66	µM	0.0757892557735917	0.439551996315592	no	1470	0.46979338209505	508	5702385			
SGTC_1887	st057648	70.8	µM	0.0748285795534021	0.439980403527963	no	1471	0.470175551181188	518	688672			
SGTC_2389	9091542	195.52	µM	0.0748033588463581	0.439991651484585	no	1472	0.470185584667373	511	3626624		YOL127W	RPL25
SGTC_1483	3453-0561	55.9	µM	0.0745309779454256	0.440113131280494	no	1473	0.470293946434875	509	4546991			
SGTC_662	k832-1615	104	µM	0.0742980049395817	0.440217039930723	no	1474	0.470386632236715	511	5878478			
SGTC_82	0054-0107	293.755	µM	0.0728507319212084	0.440862632368704	no	1475	0.470962449969156	524	3104697			
SGTC_2251	lansoprazole	556	µM	0.0721973741650856	0.441154130592111	no	1476	0.471222417417538	518	3883	Gastric proton pump inhibitor.	YBR192W	RIM2
SGTC_42	0133-0086	60.653	µM	0.0698308299088939	0.442210239700774	no	1477	0.47216415417379	528	162923	Model of phenazepam hydroxylation.		
SGTC_2148	5546263	113.568	µM	0.0697444437152564	0.442248798771867	no	1478	0.472198533457888	503	792097			
SGTC_3020	9089140	49.47	µM	0.0696470558434842	0.442292269173683	no	1479	0.472237291349933	509	17217859			
SGTC_2491	paeonol	100	µM	0.0694931152415878	0.442360984073253	no	1480	0.47229855632396	500	11092	Increases levels of cortical cytochrome oxidase.		
SGTC_2928	9011484	9.79	µM	0.0687617943443741	0.442687449493297	no	1481	0.472589614885524	516	2994751			
SGTC_271	rotenone	740	µM	0.0683453568632576	0.442873366737533	no	1482	0.472755359478707	522	5102	Inhibits electron transfer from iron-sulfur centers in mitochondria.		
SGTC_2896	9052656	71.43	µM	0.0681111742041347	0.442977922400608	no	1483	0.472848567643395	519	6469436			
SGTC_350	k064-0020	19.8	µM	0.0653020861262833	0.444232404973021	no	1484	0.473966740701611	513	2790705			
SGTC_1377	2944-0135	198	µM	0.064849225426625	0.444434696151009	no	1485	0.474147023840656	502	1894137			
SGTC_2564	betulinic acid	100	µM	0.0636007379680399	0.444992465625281	no	1486	0.474644072060128	488	6708517	Apoptosis-inducing agent of unknown mechanism.	YBR070C	ALG14
SGTC_34	0469-0683	81.75	µM	0.0633950652166288	0.445084361675143	no	1487	0.474725958367814	515	3690923			
SGTC_1749	st037932	54.2	µM	0.0628751528455555	0.445316675373052	no	1488	0.47493296042158	515	594497			
SGTC_2236	dapsone	200	µM	0.0621384095855302	0.445645908282281	no	1489	0.475226304828437	520	2955	A bacterial DFR inhibitor. An anti-cancer agent.		
SGTC_2963	9082507	9	µM	0.0619405340374492	0.445734340518726	no	1490	0.475305093979079	508	16459611			
SGTC_2862	9027634	71.43	µM	0.0617595685650018	0.44581521786469	no	1491	0.475377150801216	517	5012562			
SGTC_2675	theaflavin digallate	100	µM	0.0610573633434897	0.446129069738647	no	1492	0.475656762442818	520	467320	Theaflavin digallate is an antioxidant natural phenol found in black tea, and a theaflavin derivative.		
SGTC_3260	9137109	49.47	µM	0.0594543117049909	0.446845682699225	no	1493	0.476295127521217	524	17478346			
SGTC_2363	9053361	176	µM	0.0591467905549279	0.446983173947181	no	1494	0.47641759518803	518	6469797		YMR079W	SEC14
SGTC_1612	st002233	45.4	µM	0.0584033832614605	0.447315574113476	no	1495	0.476713659960768	523	1035021			
SGTC_3348	9149464	3.537	µM	0.0583599747412402	0.447334984538007	no	1496	0.476730947967295	517	1951442			
SGTC_313	3474-0040	5.03	µM	0.0569810936621801	0.447951626288873	no	1497	0.47728012787006	523	1043375		YIL048W	NEO1
SGTC_521	r062-0005	13.8	µM	0.054040824318596	0.449266946101738	no	1498	0.478451319321267	525	2832033			
SGTC_143	4032-1194	15.74	µM	0.0537377423746811	0.449402560763304	no	1499	0.478572056082229	525	1806963			
SGTC_1866	st057638	64	µM	0.0536950337385877	0.449421671308999	no	1500	0.478589069799071	513	688802			
SGTC_633	0437-0093	97.7	µM	0.053381905178064	0.449561788417126	no	1501	0.478713811115145	528	2831118			
SGTC_1351	1496-0003	46.5	µM	0.0517234523506195	0.450304008548995	no	1502	0.479374524987697	522	3891978			
SGTC_886	0866-0150	153	µM	0.0511730614289716	0.450550367774326	no	1503	0.479593808788517	528	271463			
SGTC_1128	3448-9350	235	µM	0.0509799126499201	0.450636827180242	no	1504	0.479670763557182	516	619386			
SGTC_2653	dihydrofissinolide	100	µM	0.0501433926930969	0.451011306542065	no	1505	0.480004060420748	524	6857746			
SGTC_108	0509-0257	621.132	µM	0.049736610751471	0.45119342370536	no	1506	0.480166140694572	501	536624			
SGTC_1545	lovastatin	49.4	µM	0.0491121229330578	0.451473028244944	no	1507	0.480414971181638	526	12923612	Lovastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YHR107C	CDC12
SGTC_2345	9052315	157.45	µM	0.0489342462783329	0.451552674114198	no	1508	0.480485848479884	517	6469265			
SGTC_2753	fluvastatin	17.09	µM	0.0485195633838802	0.451738359670842	no	1509	0.480651086738245	509	446155	Fluvastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YOR319W | YOR157C | YKL145W | YBR198C	HSH49 | PUP1 | RPT1 | TAF5
SGTC_2175	5807670	165.306	µM	0.0475955612231772	0.452152144713028	no	1510	0.481019284826526	510	241186			
SGTC_2271	7849410	118.62	µM	0.0458247643733043	0.452945284762709	no	1511	0.481724960212628	523	972430			
SGTC_2679	rapamycin	1	nM	0.0457337383663105	0.452986060419467	no	1512	0.481761236302874	523	5284616	Rapamycin is an potent immunosuppressive and anticancer drug. It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin blocks downstream elements that result in cell cycle arrest in G1. that acts by inhibiting TOR. TOR (target of rapamycin) is a phosphatidylinositol kinase-related protein kinase that controls cell growth in response to nutrients.	YHR036W | YHR186C | YKL203C	BRL1 | KOG1 | TOR2
SGTC_2037	5169046	200	µM	0.0438574658070832	0.453826657994155	no	1513	0.482509010011681	522	5718022			
SGTC_827	3253-0474	693	µM	0.0432830804397844	0.454084032583345	no	1514	0.482737939217617	518	5402065			
SGTC_364	0083-0097	67.7	µM	0.0414993686177125	0.454883413015802	no	1515	0.483448898096047	522	5207356			
SGTC_1146	3579-1023	7	µM	0.0408490531587965	0.455174901154253	no	1516	0.483708116601896	523	X1146			
SGTC_2671	danthron	100	µM	0.0407837710072423	0.4552041636316	no	1517	0.483734138727108	521	2950	Danthron, derived from the anthraquinones, is an established mutagen and genotoxin.		
SGTC_1329	1447-1697	50.6	µM	0.0407299030621172	0.455228309917151	no	1518	0.483755611086486	512	2840515			
SGTC_2556	citropten	84.59	µM	0.0404877252561347	0.45533686806705	no	1519	0.483852146422564	528	2775	A potential DNA crosslinker.		
SGTC_1071	trifluoperazine	6.31	µM	0.0398711809762292	0.455613254035243	no	1520	0.484097913537784	532	2913535	Phenothiazine antipsychotic; D2 dopamine receptor antagonist; inhibits calmodulin-dependent stimulation of 3′:5′-cyclic nucleotide phosphodiesterase; inhibits cAMP-gated cation channels.		
SGTC_3250	9135583	49.47	µM	0.0393112505335965	0.455864279633059	no	1521	0.484321118461071	516	7699353			
SGTC_1499	4480-0877	67.3	µM	0.0386342133590395	0.456167829538347	no	1522	0.484591012165162	529	2861909			
SGTC_2161	5662504	8.5105	µM	0.0386261148158216	0.456171460678843	no	1523	0.484594240606678	531	2859334			
SGTC_1094	duloxetine	25.4	µM	0.03659041496845	0.457084321888816	no	1524	0.485405793080547	525	60834	A selective serotonin reuptake inhibitor.		
SGTC_804	1595-0054	20.9	µM	0.0359695027418528	0.45736280051809	no	1525	0.485653338248702	504	761523	Stimulates phospholipase C.		
SGTC_2255	7941087	197.44	µM	0.0358840336785132	0.457401134965939	no	1526	0.485687413473624	530	935561			
SGTC_3239	9133757	49.47	µM	0.0348312534717749	0.45787335866294	no	1527	0.48610714953943	529	17036923			
SGTC_2480	5767542	37.17	µM	0.0345395360664853	0.458004218816789	no	1528	0.486223457960899	533	2867358			
SGTC_1186	1319-0216	26	µM	0.0345386508752441	0.458004615907545	no	1529	0.486223810890535	530	4565136			
SGTC_3039	9090270	49.47	µM	0.0330825767463689	0.458657857285699	no	1530	0.486804368443441	537	17173750			
SGTC_446	go6976	132	µM	0.0309552411655969	0.459612448262429	no	1531	0.487652617462968	535	3501	A protein kinase C inhibitor.		
SGTC_438	sphingosine	6.67	µM	0.030845185128961	0.459661839660182	no	1532	0.48769650251294	536	5280335	A constituent of cell membranes. Precursor of ceramide. Selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. Inhibitor of calmodulin-dependent enzymes.		
SGTC_545	4218-0007	221	µM	0.0306320587854801	0.459757489140772	no	1533	0.487781487463214	528	2840508			
SGTC_96	0929-0093	37.281	µM	0.0302340165849019	0.459936133683241	no	1534	0.48794020980642	529	6991579			
SGTC_255	tunicamycin	200.472	nM	0.0296691243642842	0.460189675733334	no	1535	0.488165468132201	529	23847177	Tunicamycin inhibits GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-actelyglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first step of glycoprotein synthesis. Tunicamycin is used as a chemical tool in research to induce the unfolded protein response pathway.	YBR243C	ALG7
SGTC_3100	9120536	49.47	µM	0.028806465038499	0.460576896572594	no	1536	0.488509472332988	535	16421196			
SGTC_3115	9123671	49.47	µM	0.0270557795654192	0.461362839167547	no	1537	0.489207622315627	536	3286988			
SGTC_517	1365-0151	113	µM	0.0243251342923995	0.462589019402329	no	1538	0.490296632397186	521	768657			
SGTC_3255	9139072	49.47	µM	0.022446823712425	0.463432670876959	no	1539	0.491045764913368	539	17646060			
SGTC_1469	k284-2957	126	µM	0.0207477977723148	0.464195937652054	no	1540	0.491723420052428	537	23884841			
SGTC_399	oxolinic acid	75	µM	0.0197719805366688	0.46463437145865	no	1541	0.492112634902866	520	4628	A DNA gyrase inhibitor.		
SGTC_2410	aloe-emodin-8-o-glycoside	46.3	µM	0.0195878083553348	0.464717124687498	no	1542	0.492186094745958	539	14077415	Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, culminating in apoptosis.		
SGTC_1415	3966-0071	78.1	µM	0.0194220996677697	0.464791583105054	no	1543	0.492252190373569	542	2893185			
SGTC_2582	agaric acid	100	µM	0.0191501718001555	0.464913771998797	no	1544	0.492360653723226	531	12629	Agaric acid is an inducer of mitochondrial permeability transition (MPT), and is used to study the MPT process at the level of the ADP and ATP exchange via the adenine nucleotide carrier/translocase.		
SGTC_1133	3473-0247	50	µM	0.0191264097979551	0.464924449446372	no	1545	0.49237013165465	538	711311			
SGTC_2470	5664817	21.68	µM	0.0188833360911834	0.465033675982772	no	1546	0.492467086522384	538	2859561			
SGTC_574	1315-0397	40	µM	0.017240955775916	0.465771757438568	no	1547	0.493122194526727	543	6794277			
SGTC_1574	spiramycin	23.7	µM	0.0161832989694171	0.466247128156851	no	1548	0.49354407960598	539	6419898	An antibiotic and protein synthesis inhibitor.		
SGTC_3211	9128781	49.47	µM	0.0158671682552263	0.46638922453791	no	1549	0.493670181320468	528	17194361			
SGTC_346	4513-0042	7.16	µM	0.0158019503531433	0.466418539616049	no	1550	0.493696196237436	534	2827372			
SGTC_2451	5856223	45.7	µM	0.015537297165936	0.466537501594993	no	1551	0.493801764621875	538	2179896			
SGTC_1953	st076800	12.1	µM	0.0152594765886558	0.466662385550428	no	1552	0.493912585856953	536	297591			
SGTC_1439	4092-1168	46	µM	0.0146542424523534	0.466934457497279	no	1553	0.494154012333797	539	2886240			
SGTC_946	3434-1334	87.4	µM	0.0144689917809998	0.467017736645735	no	1554	0.49422790882402	539	4047976			
SGTC_1080	nisoldipine	24.4	µM	0.0144288057309555	0.467035802412143	no	1555	0.494243939065054	541	4499	Nisoldipine (INN) is an L-type calcium channel blocker of the dihydropyridine class.		
SGTC_3298	9116858	71.43	µM	0.0137666286651392	0.467333495965804	no	1556	0.494508083238841	539	2506942			
SGTC_49	0717-0965	32.132	µM	0.0135457627627797	0.467432794257889	no	1557	0.494596187769648	534	5889349		YGL099W	LSG1
SGTC_2171	5739187	198.077	µM	0.013241312084584	0.467569674444214	no	1558	0.494717635123491	539	2262761			
SGTC_3134	9127454	49.47	µM	0.0126229195266855	0.467847713822978	no	1559	0.494964317428402	541	24262820			
SGTC_209	4077-0173	175.592	µM	0.0122040254408708	0.468036064355173	no	1560	0.495131419113817	535	15993494			
SGTC_2746	daunorubicin	9.88	µM	0.0115031753021667	0.468351208911174	no	1561	0.495410998218432	539	30323	Daunorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.		
SGTC_784	4579-0127	173	µM	0.010508057795789	0.468798707876965	no	1562	0.495807968607347	544	1948547			
SGTC_4	0960-0234	25.671	µM	0.0104360594527373	0.46883108667891	no	1563	0.495836690215596	522	6821112			
SGTC_863	0466-0191	129	µM	0.009900754353141	0.469071828360721	no	1564	0.496050235010013	545	765160		YPR165W	RHO1
SGTC_1022	4477-0945	21.3	µM	0.00971598975094078	0.469154924801916	no	1565	0.496123941876108	536	4648966			
SGTC_129	0088-0017	176.636	µM	0.00824623237181745	0.46981598429585	no	1566	0.496710266536746	545	182446			
SGTC_1639	Lupinine o-methylbenzoicacid ester hydrochloride	61.8	µM	0.00818576805573792	0.46984318140198	no	1567	0.496734387494754	542	17037758			
SGTC_1012	4112-3522	18	µM	0.00769798849668191	0.470062591853715	no	1568	0.49692897724563	536	3112398			
SGTC_3069	9117009	49.47	µM	0.00625776312156864	0.470710479294291	no	1569	0.497503530003541	546	41904981			
SGTC_1978	st071761	42	µM	0.00581268921632159	0.470910712188388	no	1570	0.497681085567114	546	5147680			
SGTC_2546	rhodinyl acetate	100	µM	0.00546984350153391	0.47106495898176	no	1571	0.497817859041379	536	6708682			
SGTC_717	1532-0246	73.2	µM	0.00537115463214267	0.47110936005545	no	1572	0.497857229625574	543	9561992			
SGTC_348	k064-0012	10.7	µM	0.00493620316228937	0.471305053186467	no	1573	0.498030747851081	544	5066323			
SGTC_2999	9069765	71.4286	µM	0.003897087796261	0.471772599373201	no	1574	0.49844529084294	547	2097066			
SGTC_723	4182-0001	115	µM	0.00316349694388959	0.472102699379269	no	1575	0.498737949420202	546	744821		YLR208W	SEC13
SGTC_260	nsc-65238	3.989	µM	0.00294237402924047	0.472202203674071	no	1576	0.498826164288741	544	3246252			
SGTC_1277	0873-0036	22	µM	0.00190618319023951	0.472668507799571	no	1577	0.499239543391747	545	5965735			
SGTC_1158	4092-0494	91.8	µM	0.00144174738604781	0.472877524286611	no	1578	0.49942482620931	547	1148199			
SGTC_2629	bisabolol	100	µM	0.000456257357393983	0.47332106269938	no	1579	0.499817979655707	548	6097621	A monocyclic sesquiterpene alcohol; an anti-infammatory and apoptosis inducer.		
SGTC_2172	5754775	163.918	µM	-0.000388089916856921	0.473701103479914	no	1580	0.499845174527455	549	2263357			
SGTC_2601	securinine	100	µM	-0.000543868348065738	0.473771221990903	no	1581	0.499783027931681	548	442872	A GABA receptor antagonist.		
SGTC_947	3447-0010	211	µM	-0.000676755514614124	0.473831037398209	no	1582	0.499730013632334	549	748350			
SGTC_1228	0124-0032	52.5	µM	-0.000808479317435117	0.473890329732437	no	1583	0.499677463452582	548	X1228			
SGTC_2631	bromo-3-hydroxy-4-(succin-2-yl)-caryolane gamma-lactone	100	µM	-0.00148567403170112	0.474195161914563	no	1584	0.499407302031896	548	23847180			
SGTC_2804	7954240	19.48	µM	-0.00174268868455282	0.474310858361785	no	1585	0.499304768154054	550	828705			
SGTC_891	0929-0073	133	µM	-0.00181516875656269	0.474343486025234	no	1586	0.499275852834601	549	5603632			
SGTC_2588	indole-3-carbinol	100	µM	-0.00186956410152071	0.474367972772461	no	1587	0.499254152268473	550	3712	Induces cell cycle arrest.		
SGTC_123	0083-0120	66.675	µM	-0.00208444988049062	0.474464707248777	no	1588	0.499168425413484	549	16001701			
SGTC_1026	k007-1105	30.6	µM	-0.00221258279150743	0.474522389167737	no	1589	0.499117307895786	550	7066794			
SGTC_885	0865-0106	16.8	µM	-0.00221793458553982	0.474524798410118	no	1590	0.499115172844109	549	2793380			
SGTC_1871	st057448	67.3	µM	-0.00255551533114273	0.474676770606882	no	1591	0.498980497995863	551	691747			
SGTC_753	1322-0200	289	µM	-0.00351944031020256	0.475110730836972	no	1592	0.498595949355448	550	5403907			
SGTC_1306	1185-0270	9.02	µM	-0.00367153889298629	0.475179208519488	no	1593	0.498535271192256	551	1548076			
SGTC_122	0236-0016	402.397	µM	-0.00545705922563043	0.475983138107646	no	1594	0.497822959153443	550	6808838			
SGTC_830	4076-0286	57.8	µM	-0.00550694441169943	0.476005600305599	no	1595	0.497803058142595	551	6866659			
SGTC_1909	st060837	51.5	µM	-0.00596515757092519	0.47621192713283	no	1596	0.497620260548796	552	678937			
SGTC_3091	9116372	49.47	µM	-0.00608253503312342	0.476264781552436	no	1597	0.497573434565974	552	17169793			
SGTC_792	4534-1957	155	µM	-0.00633568454225111	0.476378774791368	no	1598	0.497472444470547	554	1717904			
SGTC_2344	7990960	76.95	µM	-0.0065470908177293	0.476473972531386	no	1599	0.497388107318728	555	140813			
SGTC_3244	9134489	49.47	µM	-0.00656624959728719	0.476482599931669	no	1600	0.497380464235811	552	16584271			
SGTC_2817	7995342	71.43	µM	-0.00749345956261803	0.476900145448338	no	1601	0.497010570131065	553	18879975			
SGTC_2885	9057732	51.95	µM	-0.00897485516260447	0.477567306867406	no	1602	0.496419598880929	557	6471414			
SGTC_278	4092-0821	23.9	µM	-0.0102011728856143	0.478119639046105	no	1603	0.495930391409609	557	877900			
SGTC_2818	7996756	12.99	µM	-0.0106160425912398	0.478306505480792	no	1604	0.495764891309674	553	2241621			
SGTC_1912	st060209	90.8	µM	-0.0107721764162568	0.478376832824931	no	1605	0.495702606487209	551	688787			
SGTC_390	dec-rvkr-cmk	16.7	µM	-0.0109471621565329	0.478455652435527	no	1606	0.495632801393298	556	9962075	A caspase and metalloprotease inhibitor.	YBR109C	CMD1
SGTC_28	pentachloropyridine N-oxide	1.606	µM	-0.011443380864617	0.478679171022813	no	1607	0.495434851177693	552	140250	A respiratory chain inhibitor.		
SGTC_2904	7225135	42.03	µM	-0.0116405493996149	0.478767986211339	no	1608	0.495356197552018	554	4446116			
SGTC_3025	9087895	49.47	µM	-0.0119098907854605	0.478889313591164	no	1609	0.495248753334807	552	17173641			
SGTC_2281	7943571	200	µM	-0.0120016601881889	0.478930652435701	no	1610	0.495212145256508	555	1244024			
SGTC_456	gingerol	170	µM	-0.0123315979332633	0.479079279497374	no	1611	0.495080528882434	559	442793	A herb.		
SGTC_1148	3909-7663	27.7	µM	-0.0126249847710657	0.479211443915398	no	1612	0.494963493580748	565	4084526			
SGTC_1897	st060201	15	µM	-0.0127334256298894	0.479260294753671	no	1613	0.494920235414541	557	611878			
SGTC_2580	diallyl disulphide	81.36	µM	-0.0130995195737472	0.479425216401463	no	1614	0.494774197245219	554	16590	Diallyl disulfide is an efficient agent for detoxication of the cells. It significantly increases the production of the enzyme glutathione S-transferase (GST), which binds electrophilic toxins in the cell. 		
SGTC_2259	7964009	200	µM	-0.013244304264307	0.47949044142517	no	1615	0.494716441521156	560	313134			
SGTC_1760	st045453	10.4495	µM	-0.0141996004487101	0.479920812878088	no	1616	0.494335369375482	556	3323419		YIL048W	NEO1
SGTC_2825	7998094	58.44	µM	-0.0145075917231218	0.480059571353665	no	1617	0.494212511291225	555	2987815			
SGTC_73	0327-0325	16.231	µM	-0.0156292700030509	0.480564938334406	no	1618	0.493765077223345	559	53298			
SGTC_2924	9010168	62.78	µM	-0.0157023119867277	0.48059784815571	no	1619	0.493735941263268	558	2993929			
SGTC_76	0433-0009	400.328	µM	-0.0160602238226369	0.480759110943079	no	1620	0.493593173105277	557	2841569			
SGTC_3282	9108498	15.4605	µM	-0.0169161211729948	0.48114476162823	no	1621	0.493251765885564	557	16459645			
SGTC_2503	beta-caryophyllene alcohol	24.72	µM	-0.0176083220803127	0.48145666680645	no	1622	0.492975658823463	582	61125	An anti-inflammatory.		
SGTC_2080	5212524	12.4	µM	-0.0176185270743263	0.481461265254014	no	1623	0.492971588251341	555	260183			
SGTC_576	1073-0113	22.7	µM	-0.0208866317081369	0.482934021481456	no	1624	0.491668045325315	561	5439563			
SGTC_641	4092-0595	30	µM	-0.0215638122459645	0.483239219549701	no	1625	0.4913979502296	558	786260			
SGTC_889	0919-1524	82.7	µM	-0.0216990131232458	0.483300154329422	no	1626	0.491344025500998	566	3905452			
SGTC_1626	st003712	1.76	µM	-0.0217176816064799	0.483308568210193	no	1627	0.491336579608379	563	24207035			
SGTC_3035	9091303	49.47	µM	-0.023268935413743	0.484007743530045	no	1628	0.490717875475193	559	25237002			
SGTC_2159	5658611	73.75	µM	-0.0255053637920627	0.485015824170569	no	1629	0.489825935096475	577	793844			
SGTC_1859	st055998	20	µM	-0.0262852291330437	0.485367375002203	no	1630	0.489514918143056	574	676301			
SGTC_3169	9102970	49.47	µM	-0.0265775328321117	0.48549914378299	no	1631	0.489398346565803	560	17027839			
SGTC_1800	st050079	29.0735	µM	-0.0267223806034179	0.485564440890239	no	1632	0.489340581182371	556	3645560			
SGTC_3038	9091290	49.47	µM	-0.0269232672326841	0.485655000851231	no	1633	0.489260467837038	565	25236843			
SGTC_1185	1319-0113	81.3	µM	-0.0276881848868396	0.485999833483964	no	1634	0.488955423593306	558	4672763			
SGTC_484	loperamide	105	µM	-0.0277450237684093	0.486025457449003	no	1635	0.488932756868357	558	3955	An opioid-receptor agonist.		
SGTC_1429	4049-0205	9.46	µM	-0.0279662900913031	0.486125208737971	no	1636	0.488844518617436	561	22774478			
SGTC_2102	5377816	72.7585	µM	-0.0309084663284738	0.487451680790529	no	1637	0.487671268998315	566	1379702			
SGTC_882	0843-0131	351	µM	-0.0318151659595859	0.487860492488511	no	1638	0.487309726036178	573	5425421			
SGTC_1007	4101-0031	70	µM	-0.0323812302228994	0.488115725394435	no	1639	0.48708401537529	575	1146276			
SGTC_2632	3-hydroxy-4-(succin-2-yl)-caryolane delta-lactone	100	µM	-0.0329865588759563	0.488388667617043	no	1640	0.486842653136197	563	6857784			
SGTC_2985	9022375	71.43	µM	-0.0331177925084879	0.488447841482392	no	1641	0.486790327081118	592	4939335			
SGTC_616	4092-0450	108	µM	-0.0356345560233535	0.489582709726043	no	1642	0.485786877044306	569	787165			
SGTC_1047	2043-3044	82	µM	-0.0365771911479728	0.490007788421214	no	1643	0.485411065092499	571	669592			
SGTC_1840	st055363	71	µM	-0.0372584055605909	0.490314987263668	no	1644	0.485139485001099	581	676033			
SGTC_3190	9110366	49.47	µM	-0.0381669976212135	0.490724732703211	no	1645	0.484777266898499	571	17123768			
SGTC_2771	fluoxetine	41.05	µM	-0.038396730477808	0.490828336309811	no	1646	0.484685683881107	564	3386	A selective serotonin reuptake inhibitor.		
SGTC_311	1315-0136	58	µM	-0.0404514758952951	0.491755000312493	no	1647	0.483866595987727	575	6759207			
SGTC_534	k292-0788	63.4	µM	-0.040568701758696	0.49180786907245	no	1648	0.483819867992114	587	4146317			
SGTC_813	k007-0158	173	µM	-0.0410252493349507	0.492013772985726	no	1649	0.483637883372528	565	6523916			
SGTC_1551	6-bromo-3'-methylflavone	63.5	µM	-0.041046295450974	0.492023264879871	no	1650	0.483629494253347	577	688751			
SGTC_398	bronopol	33.3	µM	-0.0411263510809121	0.492059370374668	no	1651	0.483597583623102	585	2450	Metabolized to formaldehyde. Reacts with secondary amines and cross-links them.		
SGTC_1389	3405-0187	19	µM	-0.0419462360094676	0.492429146324898	no	1652	0.483270778902968	566	799890			
SGTC_1502	4534-4282	27.7	µM	-0.0429047973343062	0.49286147488418	no	1653	0.482888712277051	566	3278949			
SGTC_2308	7584454	197.62	µM	-0.0431148238761516	0.492956201804948	no	1654	0.482805001271616	576	893577			
SGTC_442	cape	100	µM	-0.043952227787489	0.493333894603164	no	1655	0.482471241870291	564	5281787			
SGTC_3259	9138485	49.47	µM	-0.0441227047664496	0.493410785275225	no	1656	0.482403297309972	568	17646153			
SGTC_1712	st032288	53.4	µM	-0.0452787409039108	0.493932201553399	no	1657	0.481942566178734	564	2883011			
SGTC_2639	lactacystin	53	µM	-0.0456515564633392	0.494100357807738	no	1658	0.481793987931072	571	3870	A proteasome inhibitor.		
SGTC_1596	piperlongumine	63	µM	-0.046547121510428	0.494504301355186	no	1659	0.481437088614528	584	637858	Piperlongumine selectively kills cancer cells without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1), increasing the level of reactive oxygen species (ROS) and apoptotic cell death in cancer cells. 		
SGTC_465	cgp-37157	41	µM	-0.0467225060957721	0.494583409036283	no	1660	0.481367196330604	585	2688	A selective antagonist of mitochondrial Na+/Ca2+ exchange.		
SGTC_512	prima-1	270	µM	-0.0468764338354892	0.494652838726025	no	1661	0.481305855258273	567	322968	A re-activator of the apoptotic function of mutant p53.		
SGTC_2709	st078560	56	µM	-0.0470716036066697	0.49474087102281	no	1662	0.481228079640392	578	17250903			
SGTC_2026	5148700	152	µM	-0.0482075844274954	0.495253265773494	no	1663	0.480775402859092	569	79838			
SGTC_816	0325-0417	81.3	µM	-0.0483610558741731	0.495322491120935	no	1664	0.480714247939346	569	68101			
SGTC_996	3970-0799	1.8	µM	-0.0488006516830779	0.495520777458888	no	1665	0.480539081413507	575	6615648		YGL040C	HEM2
SGTC_2301	7769476	200	µM	-0.0488196275280423	0.495529336826014	no	1666	0.48053152015909	581	977820			
SGTC_1456	k015-0012	13	µM	-0.0494097536939242	0.49579552395138	no	1667	0.480296377666832	586	2989616			
SGTC_3000	9075062	71.4286	µM	-0.0495709707280055	0.495868244153281	no	1668	0.480232140092292	561	17057871			
SGTC_706	4262-0057	46.9	µM	-0.04973963222607	0.495944322478048	no	1669	0.480164936790684	581	883298			
SGTC_3350	9150499	3.57	µM	-0.0514313069753439	0.496707395739483	no	1670	0.479490919209025	571	4910996		YPR165W	RHO1
SGTC_219	mitoxanthrone	164.414	µM	-0.0515052966054294	0.496740770954132	no	1671	0.479461440687245	578	4212	Mitoxantrone is a cytostatic anthracenedione that intercalates in DNA and increases the incidence of double-strand breaks by stabilizing the cleavable complex of topoisomerase II and DNA. 	YMR168C	CEP3
SGTC_327	1273-0057	3.96	µM	-0.0546256988847526	0.498148338695576	no	1672	0.478218332286244	577	3108138			
SGTC_2597	laccaic acid a	100	µM	-0.0552863376519872	0.498446346709759	no	1673	0.477955173246619	589	5491415	A textile dye.		
SGTC_665	3914-0008	307	µM	-0.0562463722372899	0.498879410898274	no	1674	0.477572769952484	584	1069549			
SGTC_429	1112-0049	25.5	µM	-0.0564221978643704	0.498958724639131	no	1675	0.477502736890937	571	2836170			
SGTC_265	mycophenolic acid	32.932	µM	-0.0567520288802528	0.499107509268772	no	1676	0.477371363857264	563	446541	Mycophenolic acid is a potent reversible inhibitor of IMPDH (inosine monophosphate dehydrogenase), leading to a depletion of GMP and inhibition of de novo synthesis of purines. The resulting imbalance of nucleotide pools also results in inhibiting transcription-elongation.	YHR062C	RPP1
SGTC_1846	st056244	14.8	µM	-0.0579260678027814	0.499637111467654	no	1677	0.476903759438268	591	5393182			
SGTC_266	formosanin C	406	nM	-0.0585390349850483	0.499913617747842	no	1678	0.476659635184017	577	73597	Formosanin C is a saponin glycoside isolated from the plant Paris formosana Hayata. The amphipathic nature of saponins gives them activity as surfactants that can be used to enhance penetration of macromolecules through cell membranes.	YMR211W	DML1
SGTC_1004	4084-0029	199	µM	-0.058922024309029	0.499913617747842	no	1679	0.476507107832036	579	716894		YLR208W	SEC13
SGTC_1951	sophoraflavanone G	9.2	µM	-0.0590403940349271	0.499860221778129	no	1680	0.476459967211033	592	9910234	Sophoraflavanone G is a volatile phytoncide; a natural flavanone with antimicrobial activity.		
SGTC_105	0111-0055	734.78	µM	-0.0599626350773136	0.499444203784803	no	1681	0.476092697002561	603	5179370			
SGTC_317	4495-0002	170	µM	-0.0611556682885744	0.498906033857194	no	1682	0.475617617595685	592	15991618			
SGTC_2339	9000433	200	µM	-0.0618109847877425	0.498610425408336	no	1683	0.475356677810392	572	2988954			
SGTC_1451	4152-0210	104	µM	-0.0622146618737777	0.498428330015779	no	1684	0.475195943311065	593	659563			
SGTC_48	0382-0018	55	µM	-0.0623517323761805	0.498366498719153	no	1685	0.475141366052989	567	762596			
SGTC_1489	4065-0444	182	µM	-0.0634678137436662	0.497863045834326	no	1686	0.474696994232487	569	2877968			
SGTC_2419	paclitaxel	166.5	µM	-0.0640825717826845	0.497585736175597	no	1687	0.474452239511215	575	4666	Paclitaxel is a potent anti-neoplastic and anti-mitotic taxane drug, which binds to the N-terminus of β-tubulin and and stabilizes microtubules arresting the cell cycle at the G2/M phase		
SGTC_806	3966-4455	5.86	µM	-0.0641176689696193	0.497569904307683	no	1688	0.474438266495273	608	714982			
SGTC_887	0885-0007	9.62	µM	-0.0643461991045656	0.497466817539125	no	1689	0.47434728404105	579	5719458			
SGTC_2834	9001755	58.44	µM	-0.064492666053594	0.497400748422017	no	1690	0.474288973298868	612	2989575			
SGTC_2717	st081029	62.2815	µM	-0.0649245297261677	0.497205941402687	no	1691	0.474117044948322	587	5292846			
SGTC_1727	st034309	9.9045	µM	-0.0664612858561604	0.496512740219585	no	1692	0.473505289471825	634	870305			
SGTC_1755	st041960	45.185	µM	-0.0666923168115828	0.496408527450802	no	1693	0.473413325495651	574	2257073			
SGTC_352	k048-0007	5.11	µM	-0.0685837467792107	0.495555356601169	no	1694	0.472660478295811	589	6811911			
SGTC_2920	7982904	15.77	µM	-0.0693268852593633	0.49522015308498	no	1695	0.472364712937017	581	6456808			
SGTC_1790	st045711	43.5	µM	-0.0693785122025468	0.495196866117333	no	1696	0.472344166238761	581	585119			
SGTC_2221	6807166	181.081	µM	-0.070736084709944	0.494584522456014	no	1697	0.471803900654869	574	674925			
SGTC_1478	0453-0656	35.7	µM	-0.0707699254425851	0.49456925848679	no	1698	0.471790433905231	576	5258496			
SGTC_392	N-ethylmaleimide	8.33	µM	-0.0736735408783637	0.493259605545081	no	1699	0.470635076439229	579	4362	N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It contains the imide functional group, but more importantly it is an alkene that is reactive toward thiols and is commonly used to modify cysteine residues in proteins and peptides.		
SGTC_3050	9093513	49.47	µM	-0.0739398057956197	0.493139512267628	no	1700	0.470529141037145	578	25236664			
SGTC_995	3931-2021	34.6	µM	-0.0757460765093724	0.492324848234632	no	1701	0.469810558754993	594	730143			
SGTC_2488	5268135	45.7	µM	-0.0763527333345315	0.492051240947901	no	1702	0.469569236556319	593	1270356		YLR208W	SEC13
SGTC_3083	9117465	49.47	µM	-0.0764657012017498	0.492000291906989	no	1703	0.469524300266743	621	16420915			
SGTC_1554	st069299	38.7	µM	-0.0782661412353664	0.491188303133952	no	1704	0.468808175099131	575	24207999			
SGTC_2596	sinensetin	100	µM	-0.0789345216709166	0.490886876266073	no	1705	0.468542352286747	587	145659	Isolated from citrus fruit, sinensetin exhibits antiadhesive action on platelets.		
SGTC_1592	4',5'-dihydroxyflavone	8.85	µM	-0.079372910864879	0.490689173890534	no	1706	0.468368007322454	577	688669			
SGTC_2752	diclazuril	33.15	µM	-0.0797593755299625	0.490514890052231	no	1707	0.468214317486985	604	456389	An antifungal agent for coccidioides.	YHR062C	RPP1
SGTC_2794	7785382	27.27	µM	-0.0804105352699126	0.490221240879533	no	1708	0.467955374052655	587	2205081			
SGTC_2412	st077135	33.4	µM	-0.0820777946942286	0.489469392533166	no	1709	0.46729242540102	650	13258915			
SGTC_745	0469-0705	296	µM	-0.0821254965192608	0.489447881998582	no	1710	0.4672734591567	602	3486736			
SGTC_2567	aureobasidin a	60	nM	-0.0822559215577275	0.48938906863419	no	1711	0.467221602544422	586	9963430	Aureobasidium a is a potent inhibitor of inositol phosphorylceramide (IPC) synthase in fungi.	YKL004W | YMR211W | YDR367W	AUR1 | DML1 | KEI1
SGTC_3173	9105693	49.47	µM	-0.0822570590999047	0.489388555676316	no	1712	0.467221150263439	606	17096658			
SGTC_3240	9133527	49.47	µM	-0.0824155073919436	0.489317105926899	no	1713	0.467158152442288	629	17617455			
SGTC_752	1896-0090	130	µM	-0.0824877513379579	0.489284528776554	no	1714	0.467129429078459	582	772567			
SGTC_2808	7946468	45.46	µM	-0.0832758876984539	0.488929137089607	no	1715	0.466816086257971	615	2970879			
SGTC_1630	st005209	31.3	µM	-0.0833382483531225	0.48890101738022	no	1716	0.466791294135134	574	3367314			
SGTC_2561	acetosyringone	100	µM	-0.08393986919032	0.488629736951894	no	1717	0.466552120184508	585	17198	A non-steroidal anti-inflammatory agent and anti-asthmatic agent.		
SGTC_2773	thioridazine	9.09	µM	-0.084469369258564	0.488390981276353	no	1718	0.466341627786147	583	5452	An antipsychotic.		
SGTC_2097	5376186	200	µM	-0.0850153514119534	0.488144798058612	no	1719	0.466124593116279	588	742755			
SGTC_1273	0849-0096	14.1	µM	-0.086593386827245	0.487433288007352	no	1720	0.465497361351439	599	5286025			
SGTC_3142	9086498	49.47	µM	-0.0868640711841863	0.487311244866823	no	1721	0.465389779288227	609	25236367			
SGTC_2119	5528445	120.635	µM	-0.0874621981738294	0.487041572278287	no	1722	0.465152065867239	596	791935			
SGTC_2784	7567673	72.73	µM	-0.0875271017247955	0.487012310103085	no	1723	0.465126272015821	580	3471247			
SGTC_2013	4024628	200	µM	-0.0888205574146226	0.486429162239046	no	1724	0.464612259903231	597	5230760			
SGTC_2428	5615643	7.78	µM	-0.088993225841382	0.486351317732549	no	1725	0.46454364687758	580	2253075			
SGTC_2741	miltefosine	3.04	µM	-0.0897919893693886	0.485991216136642	no	1726	0.464226257016697	580	3599	Inhibitor of protein kinase C and of phosphatidylcholine synthesis.		
SGTC_1609	st001574	46.4	µM	-0.0905499583924652	0.485649516231828	no	1727	0.463925097958134	591	3960012			
SGTC_2329	6138490	200	µM	-0.0905636414738103	0.485643347859988	no	1728	0.463919661535007	631	720019			
SGTC_264	promethazine	12.5	mM	-0.0907449915261717	0.485561595067593	no	1729	0.463847610007898	584	6014	Promethazine is a Na+ channel blocker.	YMR168C	CEP3
SGTC_1303	1160-0052	261	µM	-0.0909454403993327	0.485471233213118	no	1730	0.463767971777732	586	3562476			
SGTC_603	3794-0023	45.9	µM	-0.0912578677577385	0.485330393224757	no	1731	0.463643847451262	611	3802260			
SGTC_1210	3013-0140	750	nM	-0.0915734375705631	0.485188138498422	no	1732	0.463518478250987	591	905973			
SGTC_1933	st074711	15.9	µM	-0.0916574674017906	0.485150259271365	no	1733	0.463485095589755	585	17250958			
SGTC_466	geldanamycin	89.2	µM	-0.0919397152768575	0.485023027684724	no	1734	0.463372968422706	585	5288382	HSP90 inhibitor.		
SGTC_1401	3807-4679	7.6	µM	-0.092658133863415	0.484699186145313	no	1735	0.463087579101175	580	3291456			
SGTC_2822	7994718	71.43	µM	-0.0941239889276958	0.484038454204422	no	1736	0.462505332282045	572	1018011			
SGTC_1931	st074438	57.1	µM	-0.0944184754816505	0.48390572006664	no	1737	0.462388370027099	594	2787313			
SGTC_1326	1431-2094	10.8	µM	-0.0950530363271533	0.483619710078543	no	1738	0.462136350342941	620	616278			
SGTC_2988	9073640	71.4286	µM	-0.0958022679098029	0.483282026426904	no	1739	0.461838808057723	598	9102229			
SGTC_1410	3909-8106	77.9	µM	-0.0962278683864999	0.483090210789801	no	1740	0.461669798871339	587	1039210			
SGTC_1780	st038448	24.544	µM	-0.0964225772621677	0.483002457944404	no	1741	0.46159248080166	634	728868		YDL195W	SEC31
SGTC_2708	st078559	56	µM	-0.0968370589547304	0.482815658997332	no	1742	0.461427896714968	582	17250902			
SGTC_1408	3909-7976	48.8	µM	-0.0970801623198385	0.482706098727014	no	1743	0.461331367307552	596	24152374			
SGTC_3289	9119912	71.43	µM	-0.0973154966535571	0.482600040997998	no	1744	0.461237924930769	614	17014829			
SGTC_1168	k815-0004	80.5	µM	-0.097361082278032	0.482579497143282	no	1745	0.461219824848029	590	642433			
SGTC_1864	st057645	30.4	µM	-0.0976173987498423	0.482463985091214	no	1746	0.461118054143588	582	688666			
SGTC_854	0422-0053	192	µM	-0.0985440503282676	0.482046390939728	no	1747	0.460750147524788	588	3596728			
SGTC_1652	st011932	78	µM	-0.098771191946517	0.481944032896592	no	1748	0.460659971057929	594	1551076			
SGTC_389	tpck	16.7	µM	-0.0990999829664411	0.481795870149708	no	1749	0.460529442806648	610	439647	TPCK, N-p-Tosyl-L-phenylalanine chloromethyl ketone, is a serine/cysteine protease inhibitor capable of alkylating nucleophilic residues at the α-chloro ketone, irreversibly disabling the protease. 		
SGTC_599	1935-0052	86.5	µM	-0.0992245143730583	0.481739753350072	no	1750	0.460480005623496	600	9557311			
SGTC_907	3448-6986	75.5	µM	-0.0992308604100061	0.481736893685284	no	1751	0.460477486354156	603	590582			
SGTC_1251	0490-5699	265	µM	-0.099788080023223	0.481485801867703	no	1752	0.460256285788349	589	3883818			
SGTC_2124	5246320	200	µM	-0.100133924860765	0.481329962496579	no	1753	0.460119001264461	613	579342			
SGTC_2592	piperlongumine	83.33	µM	-0.100715635731236	0.481067847187632	no	1754	0.45988809948505	600	637858	Piperlongumine selectively kills cancer cells without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1), increasing the level of reactive oxygen species (ROS) and apoptotic cell death in cancer cells. 		
SGTC_298	1391-0729	10	µM	-0.101167797895307	0.48086411136973	no	1755	0.459708629545031	591	3237558			
SGTC_2017	5132927	60.65	µM	-0.10179157128481	0.480583058956754	no	1756	0.459461058019545	605	8367	Originally believed to exert its effects predominantly via monoamine oxidase inhibition, etryptamine was developed during the 1960s as an antidepressant by Upjohn as Monase but was withdrawn from potential commercial use due to an unacceptable incidence of agranulocytosis		
SGTC_2783	7738165	71.43	µM	-0.102141769692764	0.480425274934572	no	1757	0.459322073475291	599	17201110			
SGTC_1498	4478-3555	97.6	µM	-0.102732370285454	0.48015918320643	no	1758	0.459087690892696	590	3437919			
SGTC_100	0086-0128	49.5915	µM	-0.103041093194216	0.480020093372018	no	1759	0.458965178429857	641	93297			
SGTC_743	1275-0778	158	µM	-0.104398914411166	0.479408379316389	no	1760	0.458426392075121	611	2849257		YMR203W	TOM40
SGTC_22	0964-0034	14.468	µM	-0.105090101138984	0.479097010291802	no	1761	0.458152156978105	589	138402			
SGTC_3016	9080866	49.47	µM	-0.105109768706661	0.47908815053983	no	1762	0.45814435396904	605	17066299			
SGTC_2806	7952793	58.44	µM	-0.105819453101742	0.478768462249798	no	1763	0.457862801052306	599	2972490			
SGTC_170	4197-0004	226	µM	-0.1058285909974	0.478764346032279	no	1764	0.457859175914767	607	218692			
SGTC_2909	7941780	10.49	µM	-0.106475468162774	0.478472962283673	no	1765	0.457602559159633	613	1243215			
SGTC_737	1950-0117	57.9	µM	-0.107131596549565	0.478177423106671	no	1766	0.457342290492358	602	5393513			
SGTC_1503	4585-0012	61.3	µM	-0.108647905620272	0.477494479883813	no	1767	0.456740881218528	614	2922052			
SGTC_8	0354-0001	70	µM	-0.110540628057757	0.476642093636643	no	1768	0.455990315373291	603	4993152			
SGTC_1770	st043884	66.3	µM	-0.110644556294502	0.47659529268623	no	1769	0.455949106783064	592	670149			
SGTC_1587	estradiol valerate	56.1	µM	-0.111002482766231	0.476434113757336	no	1770	0.455807188969212	588	13791	A steroid.		
SGTC_1527	coumarin	137	µM	-0.111049021863013	0.4764131568816	no	1771	0.455788736635366	645	323	A hepatotoxic, DNA x-linker.		
SGTC_2324	6149169	200	µM	-0.112035708580908	0.475968860504195	no	1772	0.455397546720532	607	2888231			
SGTC_2420	aureobasidin a	50	nM	-0.112163425017347	0.475911353084898	no	1773	0.455346914366698	623	9963430	Aureobasidium a is a potent inhibitor of inositol phosphorylceramide (IPC) synthase in fungi.	YDR367W	KEI1
SGTC_2104	5389443	200	µM	-0.113596716906591	0.475266013383032	no	1774	0.454778745016981	614	2244536			
SGTC_3271	9137798	49.47	µM	-0.11462511872859	0.474803015321917	no	1775	0.45437113453409	600	6498326			
SGTC_2843	9000894	45.46	µM	-0.114918213262811	0.474671067071148	no	1776	0.454254974319902	589	2242070			
SGTC_826	1683-5028	118	µM	-0.115504160011039	0.474407288003036	no	1777	0.45402276166773	618	722377			
SGTC_1967	st070177	51.4	µM	-0.115568378248223	0.47437837918441	no	1778	0.453997312720129	612	5729214			
SGTC_2427	5545055	42.75	µM	-0.117405789521827	0.473551298227094	no	1779	0.453269248214339	625	5372858			
SGTC_2309	7664088	163.95	µM	-0.118287707682614	0.473154357306261	no	1780	0.452919848433574	615	704922			
SGTC_1203	3992-3522	103	µM	-0.118825642749357	0.47291225216574	no	1781	0.452706746316996	634	5322312			
SGTC_1296	1068-0102	11.9	µM	-0.119289039198605	0.472703702183627	no	1782	0.452523183473114	624	767053			
SGTC_2600	tangeritin	87.95	µM	-0.119678535296686	0.472528416586393	no	1783	0.452368902240873	624	68077	A bioactive flavone.		
SGTC_2365	9042475	200	µM	-0.120530141373064	0.472145185421686	no	1784	0.452031602160884	598	6464479			
SGTC_37	0566-0070	1.56	µM	-0.121020300679392	0.471924620551005	no	1785	0.45183747787882	625	1626686			
SGTC_1804	st050076	49.1	µM	-0.121653085261033	0.471639889032043	no	1786	0.451586884854868	596	3895976			
SGTC_1204	4049-0315	18.3	µM	-0.122029014102384	0.471470740705735	no	1787	0.451438020024712	599	588402			
SGTC_628	1636-0253	16	µM	-0.12249834386116	0.471259574075546	no	1788	0.451252178761465	619	4456143			
SGTC_689	0833-0039	98	µM	-0.122760018602516	0.471141841655024	no	1789	0.451148567627655	640	5374726			
SGTC_2884	9058502	51.95	µM	-0.123237556227996	0.470926994944067	no	1790	0.450959493327519	628	6471554			
SGTC_27	0485-0001	32.618	µM	-0.123733853920532	0.470703716946993	no	1791	0.450763003034586	603	2054479			
SGTC_1962	st076595	64.5	µM	-0.123747031409342	0.470697788688175	no	1792	0.450757786070715	605	279619			
SGTC_2680	butyl paraben	22.24	µM	-0.124155274140362	0.47051413259642	no	1793	0.450596167114536	612	7184	An antifungal and steroid mimetic.		
SGTC_1888	azatryptophan	97.5	µM	-0.126073733539552	0.469651160202367	no	1794	0.449836779572251	608	5354789	An unusual alpha-amino acid with strong fluorescent activity that is used as a vehicle for probing the structure and dynamics of protein and peptides		
SGTC_2343	7990716	14.84	µM	-0.126107765245975	0.469635853140001	no	1795	0.449823310384876	584	6456862			
SGTC_818	4072-2707	53.5	µM	-0.126526078897074	0.469447704239256	no	1796	0.449657753477017	600	882871			
SGTC_2342	7990637	118.86	µM	-0.126731465776558	0.469355327927755	no	1797	0.449576470268359	638	2033102		YER133W	GLC7
SGTC_1705	st027868	56.3335	µM	-0.130049224154261	0.46786334055464	no	1798	0.448263741049971	616	292948			
SGTC_2760	etidronate	98.04	µM	-0.130892104732058	0.467484370399866	no	1799	0.447930330229346	602	3305	A chelator and antioxidant.		
SGTC_1771	st048882	4.1505	µM	-0.130991596332621	0.467439639610224	no	1800	0.447890977638788	610	4580403			
SGTC_292	k038-0015	474	µM	-0.131082306000015	0.467398857480084	no	1801	0.44785509907303	618	46368540			
SGTC_1030	k029-0042	36.7	µM	-0.131622151753377	0.467156155494818	no	1802	0.447641581698758	601	6080581			
SGTC_2340	7987427	183.45	µM	-0.131721807066072	0.467111354136648	no	1803	0.447602168132824	602	2239331			
SGTC_1045	1348-1485	165	µM	-0.132489416655012	0.466766279144577	no	1804	0.447298596758839	606	6810614			
SGTC_1487	3970-0795	2.82	µM	-0.133823558450251	0.466166582062415	no	1805	0.446771048903125	609	3765103			
SGTC_1221	2958-7315	257	µM	-0.134156986670725	0.466016717935161	no	1806	0.446639219013449	617	4562705			
SGTC_3327	9140648	26.9345	µM	-0.134617551440822	0.465809718379788	no	1807	0.446457131942122	621	8029710			
SGTC_865	0488-0499	301	µM	-0.134830850260028	0.46571385494905	no	1808	0.446372806784564	608	9634651			
SGTC_1764	st044502	93.5	µM	-0.135025888851005	0.465626200000277	no	1809	0.446295702714067	606	8407			
SGTC_2742	clothiapine	36.27	µM	-0.136406409726748	0.465005809239189	no	1810	0.445750003406454	605	16351	An atypical antipsychotic.	YIL048W	NEO1
SGTC_2842	9000675	19.48	µM	-0.136588929719547	0.464923793113169	no	1811	0.445677863644541	592	2989072			
SGTC_3065	9113888	49.47	µM	-0.137597569680449	0.464470583471931	no	1812	0.445279238186385	643	16648368			
SGTC_508	roscovitine	141	µM	-0.137641719969854	0.464450746582783	no	1813	0.445261790773734	608	160355	A CDKinase inhibitor.		
SGTC_540	1187-0821	17.3	µM	-0.137832490853692	0.464365033531928	no	1814	0.445186402717496	597	847520			
SGTC_1048	3161-0300	24.5	µM	-0.138410390359809	0.464105394323355	no	1815	0.444958042867168	594	2165101			
SGTC_3087	9117406	49.47	µM	-0.138620946889147	0.464010799090304	no	1816	0.44487484494823	598	42546093			
SGTC_1113	artemisinin	1.17947	µM	-0.139103289981833	0.463794107919683	no	1817	0.444684264237215	630	2240	An anti-malaria and mitochondrial poison.		
SGTC_3163	9099914	49.47	µM	-0.140860968827254	0.46300456738745	no	1818	0.443989888500002	605	16268368			
SGTC_294	k038-0071	157	µM	-0.14247430871792	0.462279991370304	no	1819	0.443352685506403	609	24152826			
SGTC_2833	9001315	45.46	µM	-0.142633693997158	0.462208415718289	no	1820	0.443289742789634	602	2989378			
SGTC_1550	gossypolone	36.6	µM	-0.142737919563859	0.462161611474675	no	1821	0.443248583925771	607	5478622	Gossypolone is a phenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.		
SGTC_2727	riluzole	51.77	µM	-0.142842674247008	0.46211457015037	no	1822	0.443207216729855	593	5070	Riluzole is a sodium channel protein inhibitor and potent neuroprotective agent. It has been shown to preferentially block tetrodotoxin-sensitive sodium channels, which are associated with damaged neurons. 		
SGTC_726	3448-4391	34.2	µM	-0.144977648884475	0.461155951024569	no	1823	0.442364259467447	637	1356692			
SGTC_1584	6-fluoro-dl-tryptophan	90	µM	-0.146216550297967	0.460599778398782	no	1824	0.441875220362477	605	94937	An inhibitor of serotonin biosynthesis.		
SGTC_3136	9095672	49.47	µM	-0.146404109145671	0.460515585413608	no	1825	0.441801191817656	595	17217380			
SGTC_987	1497-1013	404	µM	-0.146453946041873	0.460493214508073	no	1826	0.441781521784186	609	1676435			
SGTC_279	1273-0055	2.93	µM	-0.146992985287727	0.460251257283396	no	1827	0.441568778553697	617	2847562			
SGTC_3101	9120531	49.47	µM	-0.147163015583975	0.460174939250371	no	1828	0.441501675998015	666	24824904			
SGTC_1738	st035555	74	µM	-0.147356945986353	0.460087895455064	no	1829	0.441425143301239	649	5331140			
SGTC_1814	st052110	31.539	µM	-0.148104765796323	0.459752261673935	no	1830	0.441130044182891	643	674163			
SGTC_1788	fluconazole	20	µM	-0.149421403581853	0.459161402911618	no	1831	0.440610561849806	601	3365	Fluconazole is a triazole antifungal; inhibits lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YHR007C	ERG11
SGTC_2984	9022109	38.96	µM	-0.14990835340604	0.458942900464425	no	1832	0.440418460565268	623	6459207			
SGTC_1280	0880-0253	10.1	µM	-0.149995293376188	0.458903890363624	no	1833	0.440384164296225	643	6836607			
SGTC_835	0312-0010	67.2	µM	-0.150310552092468	0.458762436605838	no	1834	0.44025980410338	614	1626196			
SGTC_3228	9131799	49.47	µM	-0.150812134786034	0.458537391720512	no	1835	0.440061956790973	611	17015818			
SGTC_263	alizarin	107.927	µM	-0.151304881655752	0.458316324139722	no	1836	0.439867609306527	613	6293	Alizarin, an anthraquinone, binds to and calcium and forms precipitates; used as a biological stain to quantify free calcium.		
SGTC_873	0591-4978	488	µM	-0.153353713540904	0.457397268464423	no	1837	0.439059672144197	612	3305145			
SGTC_2734	clemastine	41.6	µM	-0.15344023038598	0.457358464110128	no	1838	0.439025560619777	628	26987	Clemastine is a selective histamine H1 antagonist.		
SGTC_3243	9134147	49.47	µM	-0.153947705072218	0.457130860823498	no	1839	0.438825484604885	628	24282180			
SGTC_1051	3253-3903	78	µM	-0.154862774089187	0.456720486351143	no	1840	0.438464750752816	601	5509239			
SGTC_1331	1472-0049	76.2	µM	-0.156264043420101	0.456092158692378	no	1841	0.437912448658075	615	24051409			
SGTC_2940	9060638	45.86	µM	-0.158102368263105	0.45526802254476	no	1842	0.437188067240239	622	4027022			
SGTC_1942	st076330	65.2	µM	-0.15913824692534	0.454803714176425	no	1843	0.436779977738732	667	24208414			
SGTC_1131	3454-3128	32.3	µM	-0.159527729875718	0.454629153496014	no	1844	0.436626556389741	598	710982			
SGTC_394	menadione	8.33	µM	-0.160089776162445	0.454377267852853	no	1845	0.436405177372562	643	4055	Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. As a free radical generator, menadione is often used as a research tool to induce oxidative stress.		
SGTC_186	3455-3465	67.277	µM	-0.160231117239517	0.454313927575364	no	1846	0.436349509023982	611	755278			
SGTC_1315	1237-0019	3.69	µM	-0.160986237212987	0.453975549504499	no	1847	0.436052120182843	606	825140			
SGTC_2084	5306078	60.6385	µM	-0.162435761965456	0.453326094364539	no	1848	0.435481355401821	642	679340			
SGTC_2844	9010103	25.97	µM	-0.162965436204346	0.453088806484352	no	1849	0.435272824365188	672	2480525			
SGTC_2775	cyproheptadine	69.59	µM	-0.163043190337461	0.453053974947573	no	1850	0.435242214327868	613	2913	A selective serotonin reuptake inhibitor.		
SGTC_2678	equilin	100	µM	-0.163612233586278	0.45279907152508	no	1851	0.435018206740688	606	3247	Equilin is an estrone commonly used hormone replacement therapy		
SGTC_3165	9101544	49.47	µM	-0.164528594778248	0.452388627649723	no	1852	0.434657519041876	634	5002184			
SGTC_1717	st033143	58.0435	µM	-0.165640082285905	0.451890853801035	no	1853	0.434220100940476	639	674616			
SGTC_2619	obliquin	87.91	µM	-0.167261695631601	0.451164758628464	no	1854	0.433582070983911	620	6708593	A bioactive alkalod.	YER133W	GLC7
SGTC_2748	diazoxide	86.69	µM	-0.167291668548173	0.451151339456401	no	1855	0.433570279649196	605	3019	A potassium channel activatior.		
SGTC_2136	5328288	199.296	µM	-0.16833321032083	0.450685065655509	no	1856	0.433160574282515	621	262395			
SGTC_3140	9094243	49.47	µM	-0.169940101658746	0.449965831831649	no	1857	0.432528621611591	639	19291112			
SGTC_2732	terfenadine	20	µM	-0.170082659986522	0.449902031577748	no	1858	0.43247256507492	613	5405	A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. 		
SGTC_2880	9042983	58.44	µM	-0.17058729472019	0.449676198826974	no	1859	0.432274144414991	654	6464714			
SGTC_631	k072-0230	41.5	µM	-0.171344810864617	0.449337227898732	no	1860	0.431976323723824	654	5773147			
SGTC_902	1120-0002	2.07	µM	-0.171551716330621	0.449244648912789	no	1861	0.431894984674356	635	3280475			
SGTC_325	2810-4341	181	µM	-0.171948739905192	0.449067010115805	no	1862	0.431738914139636	618	774970			
SGTC_1797	st048695	56.8	µM	-0.172168046906067	0.448968890766172	no	1863	0.431652708810548	624	592262		YIL048W	NEO1
SGTC_950	1165-0508	94.1	µM	-0.1725784460951	0.448785283943128	no	1864	0.431491397595837	635	6148369			
SGTC_58	0957-0393	9	µM	-0.173067641109663	0.448566439308376	no	1865	0.431299129877396	631	6997992			
SGTC_487	nimodipine	119	µM	-0.173071389311991	0.448564762585531	no	1866	0.431297656788798	613	4497	L-type voltage-gated calcium channels inhibitor		
SGTC_1019	4262-0212	3.4	µM	-0.173787889623619	0.448244259859448	no	1867	0.43101608112248	620	4677213			
SGTC_648	0375-0473	33.3	µM	-0.174087558992896	0.448110222681084	no	1868	0.430898325196117	637	1713139			
SGTC_1843	st055809	45.5	µM	-0.176468238952135	0.447045595421332	no	1869	0.429963049367187	628	16413835			
SGTC_3344	9148862	3.898	µM	-0.176617576171689	0.446978825256757	no	1870	0.429904393668541	657	4905352			
SGTC_2487	5918373	44.05	µM	-0.176749655703709	0.446919772429245	no	1871	0.429852517620971	614	2876279			
SGTC_3129	9127257	49.47	µM	-0.176880446449809	0.446861296978315	no	1872	0.429801148955108	678	837894			
SGTC_787	4152-0075	138	µM	-0.177315294314573	0.446666888440374	no	1873	0.429630369008634	606	9566539			
SGTC_1116	jasmonic acid 	1.58368	µM	-0.178265246706109	0.446242235461191	no	1874	0.429257335366336	653	5281166	Jasmonic acid (JA) is a plant hormone derived from the fatty acid linolenic acid.		
SGTC_246	cycloheximide	667	µM	-0.178432149248858	0.446167632115604	no	1875	0.429191801477061	619	16760040	Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effect by interfering with the translocation step in protein synthesis  thus blocking translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells.		
SGTC_2840	9008771	71.43	µM	-0.178458225695165	0.446155976442856	no	1876	0.42918156279823	595	2992978			
SGTC_727	3032-0951	202	µM	-0.178957703318601	0.445932728490577	no	1877	0.428985456669147	638	3652836			
SGTC_3013	9080133	71.4286	µM	-0.178970987909691	0.445926791005297	no	1878	0.428980241079512	625	17050193			
SGTC_2257	7960413	200	µM	-0.182108406092985	0.444524879245465	no	1879	0.427748825967049	624	2974689		YIL048W	NEO1
SGTC_2810	7959871	45.46	µM	-0.182662771947458	0.44427724017608	no	1880	0.427531313958919	637	2974535			
SGTC_3046	9092212	49.47	µM	-0.183072843058885	0.444094072559247	no	1881	0.427370431870005	607	25236637			
SGTC_2756	carbadox	75.1	µM	-0.183849720265913	0.443747095402354	no	1882	0.427065674873973	619	2553	A substituted quinoxaline antibiotic.	YLR208W	SEC13
SGTC_1283	0922-0125	16.4	µM	-0.185099673168516	0.443188918759599	no	1883	0.426575428975564	619	3360884			
SGTC_2874	9043904	71.43	µM	-0.185386584360907	0.443060812097087	no	1884	0.426462915084651	632	4463428			
SGTC_2535	4',4'-dimethoxydalbergione	51.19	µM	-0.185730019050526	0.442907475359781	no	1885	0.426328243045679	631	364106			
SGTC_982	1491-0518	27.5	µM	-0.186612329868262	0.442513580437486	no	1886	0.425982299369093	622	3091256			
SGTC_3052	9092717	49.47	µM	-0.186969628291926	0.442354085858253	no	1887	0.425842223054274	643	25237534			
SGTC_119	0121-0043	24.815	µM	-0.187759453293498	0.442001548766897	no	1888	0.425532610989437	647	1092378			
SGTC_881	0833-0569	170	µM	-0.188749288215657	0.441559802460209	no	1889	0.425144659712321	617	5418700			
SGTC_1598	3(2'-chlorophenyl)-7-hydroxy-4-phenylcoumarin	19.1	µM	-0.189046923969444	0.441426986929208	no	1890	0.425028019900824	620	6312947			
SGTC_1355	1499-0035	1.68	µM	-0.189560480165402	0.441197835605103	no	1891	0.424826778945885	632	1548538			
SGTC_144	4161-2749	112.381	µM	-0.18987902704842	0.441055708291145	no	1892	0.424701963734591	625	797501		YMR168C	CEP3
SGTC_3153	9100258	49.47	µM	-0.191007966565165	0.440552066162017	no	1893	0.424259675827657	661	25236848			
SGTC_2115	tiliquinol	12.7705	µM	-0.191742462326974	0.440224444730014	no	1894	0.42397197146504	665	71208	A bioactive hydroxyquinoline.		
SGTC_1803	st050068	52.4	µM	-0.191896197814405	0.440155876271572	no	1895	0.42391175790061	637	3984059		YIL048W | YNL267W	NEO1 | PIK1
SGTC_2134	5324836	1.464	µM	-0.192379381917516	0.43994038021508	no	1896	0.423722520798154	609	699272			
SGTC_1624	st003710	6.25	µM	-0.192998293889908	0.439664376666221	no	1897	0.423480152124804	676	24207033			
SGTC_1686	st019653	115.5	µM	-0.193939685846127	0.439244619561466	no	1898	0.423111554393369	664	97252			
SGTC_999	SEC7.066	22.7	µM	-0.19468347369709	0.43891302039934	no	1899	0.422820375218988	625	740511		YDR170C	SEC7
SGTC_1450	4112-4260	37.6	µM	-0.194933972865043	0.438801351265456	no	1900	0.422722318915026	617	1633175			
SGTC_2910	7948405	25.97	µM	-0.194992942579637	0.438775064073956	no	1901	0.422699236291829	626	2971328			
SGTC_3248	9135562	49.47	µM	-0.195656421717806	0.438479320672239	no	1902	0.422439547750595	632	17650701			
SGTC_1463	k081-0032	34.1	µM	-0.196018084443512	0.438318125288371	no	1903	0.42229800561833	650	977755			
SGTC_267	4-Nitroquinoline-1-oxide  (4-NQO)	44.4	nM	-0.197579547462288	0.437622289054627	no	1904	0.421687019050229	660	5955	4-Nitroquinoline 1-oxide (also known as 4-NQO) is a quinoline derivative and a tumorigenic compound. 4-NQO induces DNA lesions that require nucleotide exicision repair.		
SGTC_50	0929-0078	56.389	µM	-0.198154584739193	0.437366083129323	no	1905	0.4214620594945	637	1377751			
SGTC_2606	farnesol	9.78	µM	-0.198790181236251	0.437082925806844	no	1906	0.421213438474095	623	445070	Farnesol is a polyprenyl alcohol found in plant essential oils. Induces apoptosis in cell cultures.		
SGTC_1748	st037455	53.6035	µM	-0.199256689537261	0.436875117530736	no	1907	0.421030978266526	647	580690			
SGTC_2151	5563267	85.4165	µM	-0.199832744313505	0.436618535309883	no	1908	0.420805695768755	651	5310824			
SGTC_1440	4100-1550	40	µM	-0.200886572399104	0.436149215781783	no	1909	0.420393633681512	658	742806			
SGTC_2890	9046729	58.44	µM	-0.201468548863305	0.43589007259886	no	1910	0.420166109788934	646	903329			
SGTC_2511	berberine	10.47	µM	-0.201816019949821	0.43573536336816	no	1911	0.420030278565103	639	12456	Berberine is a quaternary ammonium salt and isoquinoline alkaloid.		
SGTC_565	1418-0001	44.5	µM	-0.201921985125285	0.435688185021939	no	1912	0.419988857216029	675	2862145			
SGTC_2474	5321570	43.32	µM	-0.202227979716094	0.435551953717198	no	1913	0.419869250171743	660	2841384			
SGTC_168	3970-0862	530.542	µM	-0.202976772465194	0.435218617324064	no	1914	0.419576593596113	630	3135186			
SGTC_3172	9105863	49.47	µM	-0.204739692111376	0.434434009205719	no	1915	0.418887753710956	640	2348785			
SGTC_2378	9074213	121.43	µM	-0.205012971362916	0.434312406097129	no	1916	0.418780995295752	623	657714			
SGTC_256	clotrimazole	625	nM	-0.205139849032611	0.43425595050523	no	1917	0.418731431695886	629	2812	Clotrimazole, an imidazole antifungal; inhibits lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YGL116W | YJL195C	CDC20 | YJL195C
SGTC_189	3970-0742	2.116	µM	-0.205978538719151	0.433882800233274	no	1918	0.418403837732644	655	2891807			
SGTC_1369	1866-0067	208	µM	-0.206533981827064	0.433635704591579	no	1919	0.418186911615869	655	3531355			
SGTC_962	1254-0300	21.5	µM	-0.207078092150065	0.43339367562328	no	1920	0.417974435600647	635	7340576			
SGTC_2743	auranofin	4.32	µM	-0.207482301758755	0.433213892892917	no	1921	0.417816606548785	620	16667669	Auranofin is used to treat rheumatoid arthritis and is thought to inhibit selenocysteine-containing flavoreductases (thioredoxin reductase and thioredoxin glutathione reductase) more effectively than non Se-containing ones (glutathione reductase); this preference has been ascribed to the high affinity of selenium for gold.		
SGTC_1037	k284-1091	78.7	µM	-0.207991561515365	0.432987406057715	no	1922	0.417617778106511	641	3334711			
SGTC_2557	derrustone	83.84	µM	-0.208789321881974	0.432632656498622	no	1923	0.417306353768461	696	629853	An antioxidant.		
SGTC_2796	7949634	45.45	µM	-0.210048426430526	0.432072866129707	no	1924	0.416814938592485	636	2971588			
SGTC_770	0389-1121	67.2	µM	-0.210420793201975	0.43190734015942	no	1925	0.416669632648369	628	6753108			
SGTC_676	falcarinol	140	µM	-0.210560243348251	0.431845354296227	no	1926	0.416615218973427	658	3322	Farnesol is a natural pesticide found in carrots. Preliminary research in animal models suggest that falcarinol may have a protective effect against certain types of cancer.		
SGTC_1636	st007707	68.9	µM	-0.210587091188008	0.431833420571437	no	1927	0.416604743085863	673	403051			
SGTC_3162	9099653	49.47	µM	-0.211832218362518	0.431280036552025	no	1928	0.416118966121341	627	25237511			
SGTC_2018	5133068	143	µM	-0.213260058416038	0.430645613725424	no	1929	0.415562062839015	652	785362			
SGTC_1395	3486-0190	4.35	µM	-0.21341797894822	0.430575456890013	no	1930	0.415500479174866	664	6748079			
SGTC_3107	9121808	49.47	µM	-0.214598196965024	0.430051209787783	no	1931	0.415040299900264	624	662681			
SGTC_206	4546-0025	72.014	µM	-0.214901215476011	0.429916630293412	no	1932	0.414922168609328	689	6620745		YIL048W	NEO1
SGTC_1384	3089-0840	101	µM	-0.215819752153978	0.429508730766133	no	1933	0.414564125570058	644	1069836			
SGTC_781	4335-2806	94.4	µM	-0.216453068743098	0.429227534258245	no	1934	0.414317301845817	678	845254			
SGTC_2300	7976697	71.57	µM	-0.217328268939894	0.428838999053559	no	1935	0.413976264049155	625	2236109			
SGTC_2244	6635614	200	µM	-0.219303861660653	0.427962211102915	no	1936	0.413206676974883	622	836499			
SGTC_1852	st056254	31.4	µM	-0.219465643576472	0.427890426351541	no	1937	0.413143669973041	644	442583			
SGTC_841	0251-0215	91.2	µM	-0.219909662478497	0.427693421629766	no	1938	0.412970755471743	664	3888614			
SGTC_815	1582-0027	36.9	µM	-0.220628758452817	0.427374407472078	no	1939	0.412690753396247	636	3128206			
SGTC_3075	9116269	49.47	µM	-0.220775277203058	0.427309412846967	no	1940	0.412633707269379	668	17015205		YNL244C	SUI1
SGTC_1219	1469-0211	33.1	µM	-0.221782130854064	0.426862833528336	no	1941	0.412241745289618	670	6822282			
SGTC_2966	9084041	48.03	µM	-0.22181256761273	0.426849335081674	no	1942	0.412229897806152	650	17741380			
SGTC_1766	st045414	44.774	µM	-0.222615853831802	0.426493115406769	no	1943	0.411917248244757	636	253960			
SGTC_2072	5231554	129	µM	-0.222747777140549	0.426434619345108	no	1944	0.411865907297289	658	789545			
SGTC_1008	4106-0037	6	µM	-0.222812521431775	0.426405911696688	no	1945	0.411840711139871	694	2905394			
SGTC_2701	st077767	14.721	µM	-0.22339688575908	0.42614682194568	no	1946	0.41161331394733	657	5721188			
SGTC_104	0074-0074	590.992	µM	-0.223436004055449	0.426129479194329	no	1947	0.411598092669471	663	3943124			
SGTC_1948	st076329	66.6	µM	-0.223554771910376	0.426076825389822	no	1948	0.411551879853531	641	24208413			
SGTC_1166	k206-0078	225	µM	-0.223559392912955	0.426074776769815	no	1949	0.411550081836744	644	5404595			
SGTC_861	0443-0273	110	µM	-0.224137532210878	0.425818487165379	no	1950	0.411325144417692	642	6149169			
SGTC_2660	2',4'-dihydroxychalcone	17.14	µM	-0.224258166108892	0.425765014011303	no	1951	0.41127821290082	648	5357218	A potent inhibitor of glutathione S-transferases.		
SGTC_2348	9022543	33.42	µM	-0.224392151945606	0.425705623969466	no	1952	0.411226088422292	662	3162678		YDL140C	RPO21
SGTC_81	0411-0046	9.971	µM	-0.224663354715393	0.425585416842247	no	1953	0.411120587269798	655	12925265			
SGTC_967	1306-0166	352	µM	-0.224912869679433	0.42547482866332	no	1954	0.411023528612889	625	4437607			
SGTC_3164	9100705	49.47	µM	-0.22662804600613	0.424714799995949	no	1955	0.41035649104409	659	17174235			
SGTC_1934	st074720	32.6	µM	-0.227478503492311	0.42433804899234	no	1956	0.410025841423333	629	17250992			
SGTC_459	nigericin	15.3	µM	-0.229391863106616	0.423490687627458	no	1957	0.409282179935381	694	34230	Nigericin is a polyether antibioitc and K+/Na+ ionophore, stimulates Ca2+ release from mitochondrial stores by disruption of membrane potential leading to rapid intracellular acidification.		
SGTC_732	3970-1727	52.7	µM	-0.22979669292645	0.423311447587036	no	1958	0.409124877313975	668	1275699			
SGTC_1957	st077035	62.4	µM	-0.231316086270155	0.422638871886294	no	1959	0.408534625251904	660	705593			
SGTC_672	1441-0018	53.7	µM	-0.233086927839104	0.421855274582526	no	1960	0.407846952723479	645	251141			
SGTC_1371	2421-0008	32.7	µM	-0.234699951483478	0.421141780780631	no	1961	0.407220812697094	672	2827552			
SGTC_3222	9128301	49.47	µM	-0.235616566173189	0.420736446942808	no	1962	0.406865108695563	656	4911358			
SGTC_461	N-acetylfarnesylcysteine	136	µM	-0.235837069182471	0.420638951391801	no	1963	0.406779551146248	655	6438381	Potential activator of peroxisome proliferator-activated receptor γ (PPARγ).		
SGTC_2656	pseudo-anisatin	100	µM	-0.236419435592416	0.420381481120447	no	1964	0.406553608091438	638	6708809	A neurotoxin.		
SGTC_527	4476-4215	268	µM	-0.236575831020917	0.420312342865839	no	1965	0.406492936019113	631	4418754			
SGTC_3293	9120939	62.045	µM	-0.23657928245972	0.420310817104366	no	1966	0.406491597092598	692	934087			
SGTC_415	dibenzyl ketone	100	µM	-0.23734159726128	0.419973853530853	no	1967	0.406195896948345	674	7593			
SGTC_1036	k216-0215	33.5	µM	-0.238197175987889	0.419595734672269	no	1968	0.405864083665181	651	622330			
SGTC_541	4513-1321	94	µM	-0.24006757354665	0.418769380525992	no	1969	0.40513893588519	633	747515			
SGTC_2374	9071832	200	µM	-0.240593743843295	0.418536979387627	no	1970	0.404934999733816	667	17381698			
SGTC_1043	0916-0009	19.3	µM	-0.240742413908264	0.418471319308091	no	1971	0.40487738199848	697	3101130			
SGTC_1279	0874-0590	65.2	µM	-0.240981252050382	0.418365841287164	no	1972	0.40478482354762	649	3523074			
SGTC_2900	5328528	85.29	µM	-0.244470239526705	0.416825673744966	no	1973	0.403433324113056	633	795359			
SGTC_1621	st003705	32.4	µM	-0.246058015960009	0.416125191718531	no	1974	0.40281866122457	646	24207032			
SGTC_2969	9091408	28.7	µM	-0.246060657516663	0.41612402655981	no	1975	0.402817638820022	661	4286311			
SGTC_618	k072-0232	33.2	µM	-0.246440994657262	0.415956272141951	no	1976	0.402670437702527	696	5872756		YGL099W	LSG1
SGTC_1272	0839-0021	27	µM	-0.246757915302952	0.415816500383808	no	1977	0.402547791080256	674	5027250			
SGTC_1835	st008666	49.2	µM	-0.247014377826267	0.415703400312675	no	1978	0.402448548453664	659	690455			
SGTC_690	glyoxal	20.3	µM	-0.247019336165227	0.415701213752065	no	1979	0.402446629800235	658	7860	Glyoxal is a potent glycating agent that covalently cross-links proteins.		
SGTC_2852	9023854	51.95	µM	-0.24743308027752	0.415518767380344	no	1980	0.402286537783013	684	19798528			
SGTC_2285	7945142	200	µM	-0.248312843502645	0.415130883808108	no	1981	0.40194618123362	687	2970608			
SGTC_2101	5377231	179.231	µM	-0.248327883662412	0.415124253388623	no	1982	0.401940363249058	687	2844213			
SGTC_1454	4239-0054	42.6	µM	-0.248980827719062	0.414836427848309	no	1983	0.401687805884281	686	1340767			
SGTC_2764	methyldopa	94.69	µM	-0.249678402977387	0.414528978848413	no	1984	0.401418030629046	687	38853	An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.		
SGTC_307	1501-1223	22.3	µM	-0.250838268804818	0.414017896099887	no	1985	0.400969576496224	680	2830329			
SGTC_2766	oltipraz	83.91	µM	-0.251422584369148	0.413760478647083	no	1986	0.400743704286724	664	47318	Oltipraz is an antischistosomiasis drug found to inhibit carcinogenesis. Its mechanism of action is believed to be the induction of phase II detoxifying enzymes resulting in diminished carcinogen-DNA binding.	YMR203W	TOM40
SGTC_1197	1601-0112	267	µM	-0.251539412567003	0.413709014979655	no	1987	0.40069854731948	661	7350313			
SGTC_1900	st060200	72.8	µM	-0.252810799909418	0.413149055656261	no	1988	0.400207210813908	637	688945			
SGTC_3241	9133421	49.47	µM	-0.253389580948825	0.412894200563347	no	1989	0.399983589102408	664	17018221			
SGTC_3218	9131285	49.47	µM	-0.25344465957975	0.412869949659359	no	1990	0.39996231026211	693	17156417			
SGTC_1522	st012842	45.6	µM	-0.254180424657365	0.41254602712261	no	1991	0.399678086471723	667	3491067		YOR116C	RPO31
SGTC_811	0416-0114	265	µM	-0.254514361233372	0.412399030289652	no	1992	0.399549105324638	672	6612453			
SGTC_705	1124-0212	310	µM	-0.254933074621264	0.412214732588297	no	1993	0.399387395096052	649	9554485			
SGTC_807	1315-0151	48	µM	-0.255254226303249	0.41207339002055	no	1994	0.399263375619952	687	4011080			
SGTC_2337	9009472	200	µM	-0.256075049436016	0.411712188139371	no	1995	0.398946443729478	674	5742383			
SGTC_1032	k061-1018	98.7	µM	-0.258067818450008	0.41083558520121	no	1996	0.398177283840424	693	4005393			
SGTC_3063	1327-0034	4	µM	-0.258177060477812	0.410787543348789	no	1997	0.398135130508577	643	15998580		YGL093W | YPR107C	SPC105 | YTH1
SGTC_1660	st012960	28.1	µM	-0.259306143566446	0.410291079980584	no	1998	0.397699519803923	691	24207266			
SGTC_2684	capsaicin	100	µM	-0.259752377100548	0.410094908492886	no	1999	0.397527393905847	683	1548943	An isomer of capsaicen, an agonist at the TRPV1 receptor, a ligand-gated non-selective cation channel.		
SGTC_2957	9076800	11.52	µM	-0.259988323143353	0.409991191881278	no	2000	0.397436390374489	691	16459615			
SGTC_2625	euphol	100	µM	-0.26050119711884	0.409765765663314	no	2001	0.397238596007164	642	6708538	A triterpene alcohol.		
SGTC_1546	5-methoxyflavanone	78.7	µM	-0.260783161726555	0.409641844964792	no	2002	0.397129865125975	657	147795			
SGTC_1422	4031-0024	15.5	µM	-0.260897381797805	0.409591648924162	no	2003	0.397085821982825	671	782427			
SGTC_32	0928-0142	34.1	µM	-0.261643578633379	0.409263755961943	no	2004	0.396798121561988	664	2244242			
SGTC_2302	7771753	200	µM	-0.262415851457871	0.40892447155692	no	2005	0.396500426540372	647	2203047			
SGTC_2041	5107442	45.335	µM	-0.262500162119317	0.408887435285668	no	2006	0.396467930193107	657	793005			
SGTC_2036	5160441	105	µM	-0.262697588591928	0.408800712303397	no	2007	0.39639183777684	658	134534		YIL048W	NEO1
SGTC_834	0312-0008	75.7	µM	-0.263100445543839	0.40862376429597	no	2008	0.396236580272806	671	6385573		YIL048W	NEO1
SGTC_3036	9090181	49.47	µM	-0.263106094331323	0.408621283295271	no	2009	0.396234403397029	649	25236586			
SGTC_778	3456-2434	196	µM	-0.263369386340412	0.408505647028465	no	2010	0.39613294202782	663	5539063			
SGTC_3321	9137793	26.8275	µM	-0.263802609118916	0.408315395530644	no	2011	0.395966011993891	649	4904192			
SGTC_1441	4106-0040	13	µM	-0.264391704089872	0.408056726821026	no	2012	0.395739051671507	652	2904180			
SGTC_1320	1313-0481	95.3	µM	-0.264530070304947	0.407995976701628	no	2013	0.395685748513009	676	6813365		YLR208W	SEC13
SGTC_478	N-arachidonylglycine	10	µM	-0.264536297337082	0.407993242755695	no	2014	0.395683349703922	643	5283389			
SGTC_614	0462-0418	107	µM	-0.264592186001533	0.407968705330032	no	2015	0.395661820164373	655	5188303			
SGTC_3023	9089636	49.47	µM	-0.265293294021946	0.40766092072674	no	2016	0.3953917650434	641	17249241			
SGTC_1851	st056236	18.9	µM	-0.265962578712871	0.407367159643717	no	2017	0.395134014594182	656	5393171			
SGTC_1361	1608-0041	5.61	µM	-0.266468948247833	0.407144939555533	no	2018	0.394939035420837	660	X1361			
SGTC_3017	9080681	49.47	µM	-0.266863779807231	0.40697168860016	no	2019	0.394787022544811	678	16451914			
SGTC_1839	st053978	48	µM	-0.26695298587447	0.406932547753467	no	2020	0.394752679810405	645	3788398			
SGTC_3	0833-0587	95.581	µM	-0.267222609074478	0.406814251134592	no	2021	0.394648884691356	658	5382644			
SGTC_1337	1486-1011	40.3	µM	-0.267550270434081	0.406670501838855	no	2022	0.394522757059768	656	X1337			
SGTC_391	gliotoxin	8.33	µM	-0.268201053082108	0.406385032343598	no	2023	0.394272282219408	674	6223	A prooxidant peroxiredoxin mimetic; causes catalytic oxidation of thioredoxin and glutathione depletion		
SGTC_2995	9067767	71.4286	µM	-0.268339369552004	0.406324365446194	no	2024	0.394219052262764	684	11673567			
SGTC_1745	st081495	74	µM	-0.268364998558595	0.40631312457109	no	2025	0.394209189367139	657	13842402		YBL026W	LSM2
SGTC_3187	9109394	49.47	µM	-0.268601387666704	0.40620944801632	no	2026	0.394118222161623	654	17098090			
SGTC_1327	1436-0082	2.18	µM	-0.269194321278194	0.405949425584533	no	2027	0.39389007500051	673	15992205			
SGTC_210	3551-0445	56.827	µM	-0.269210042629216	0.405942531778214	no	2028	0.393884026282892	694	2865180		YOR207C	RET1
SGTC_1516	st013856	110	µM	-0.271200600622736	0.405069909195382	no	2029	0.393118375527393	684	5281404	A mutagen and neurotoxin.		
SGTC_2698	st077697	67.5	µM	-0.273590811544394	0.404022710084447	no	2030	0.39219954800155	655	3154499			
SGTC_2622	2-methoxyxanthone	59.94	µM	-0.27437467958086	0.403679431177692	no	2031	0.391898349700281	650	71034	A hepatoprotective.		
SGTC_1191	1487-1166	10.6	µM	-0.274579193964312	0.403589880495642	no	2032	0.391819776476384	689	3955771			
SGTC_1182	1222-0449	220	µM	-0.274619773230107	0.403572112659445	no	2033	0.391804186685493	655	658318			
SGTC_1756	st041558	35.5	µM	-0.274623464937021	0.403570496236829	no	2034	0.391802768409734	708	3955792			
SGTC_570	0987-0065	62.6	µM	-0.27506671037985	0.403376432148793	no	2035	0.391632493335727	645	3104428			
SGTC_314	1671-0008	2.74	µM	-0.275218127028599	0.403310143552026	no	2036	0.391574330587156	693	3913060			
SGTC_759	3486-0358	89.3	µM	-0.275310844745438	0.403269554094003	no	2037	0.391538716695658	658	875103			
SGTC_1528	arabinosylhypoxanthine	74.6	µM	-0.275857299976345	0.403030351077764	no	2038	0.391328835727981	687	804	An inhibitor of viral and cellular DNA polymerases.		
SGTC_837	0091-0265	12.5	µM	-0.276136261285974	0.402908253710329	no	2039	0.391221705256703	665	759367			
SGTC_842	0271-0008	11.1	µM	-0.279554339985135	0.401412981788613	no	2040	0.38990972109133	676	1221709			
SGTC_2481	5478948	45.16	µM	-0.280527594587917	0.400987484945836	no	2041	0.389536378798303	664	77792			
SGTC_2733	amorolfine	100	µM	-0.2807334990813	0.400897480663783	no	2042	0.389457406498925	676	54260	Amorolfine is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in fungal cytoplasmic cell membranes. 	YDL196W	YDL196W
SGTC_1256	0570-0116	285	µM	-0.282199697688806	0.400256733196516	no	2043	0.388895195056969	688	410638			
SGTC_2728	chlorpromazine	9.18	µM	-0.28264913322501	0.400060377804775	no	2044	0.388722906260981	681	2726	A thorazine and dopamine antagonist.		
SGTC_1936	st074407	74.3	µM	-0.283232734059231	0.399805444196317	no	2045	0.388499218553995	654	809813			
SGTC_1359	1582-0056	520	nM	-0.28359243006703	0.399648339911021	no	2046	0.388361369487171	687	3661189			
SGTC_2327	6189656	200	µM	-0.284230713298239	0.399369597199432	no	2047	0.388116789920552	708	5349088			
SGTC_1347	1493-0251	600	nM	-0.284474110638839	0.399263317394792	no	2048	0.38802353576959	669	3986378			
SGTC_560	2332-1943	155	µM	-0.285085625181682	0.398996331634222	no	2049	0.38778927136702	668	21177716			
SGTC_493	zm226600	134	µM	-0.286117835735518	0.39854577826215	no	2050	0.387393935696794	710	5240098	A potassium channel opener.	YCR052W	RSC6
SGTC_3099	9120367	49.47	µM	-0.286390049126751	0.398426981343209	no	2051	0.387289697661004	681	24824940			
SGTC_2217	6934799	96.0675	µM	-0.287365257890514	0.398001466844392	no	2052	0.38691633000723	682	675606			
SGTC_2114	5491910	81.25	µM	-0.287511857466995	0.397937511276567	no	2053	0.38686021204721	696	2849228			
SGTC_2267	7931562	200	µM	-0.289379820062648	0.397122834109551	no	2054	0.386145367982637	659	934880			
SGTC_2579	2',5'-dihydroxy-4-methoxychalcone	13.23	µM	-0.289456270137556	0.397089501363829	no	2055	0.386116119784303	660	5355888			
SGTC_1994	st072947	40.9	µM	-0.290673162489412	0.396559029499968	no	2056	0.385650649491971	712	5286565		YDL195W	SEC31
SGTC_843	0310-0051	143	µM	-0.290679400475204	0.396556310708207	no	2057	0.385648263839984	672	2065037			
SGTC_2913	7966556	36.57	µM	-0.294283332249599	0.394986401772347	no	2058	0.384270703994471	684	2976516			
SGTC_2006	4011487	200	µM	-0.295691797577283	0.394373321607179	no	2059	0.383732730909952	670	45595294			
SGTC_1386	3228-0095	33.8	µM	-0.296319569682738	0.39410014764366	no	2060	0.383493021120594	715	870181			
SGTC_736	0958-0254	92.6	µM	-0.296876920381586	0.39385766108296	no	2061	0.38328023854804	721	6812352			
SGTC_419	nsc-638432	893	µM	-0.297911328618502	0.393407730222264	no	2062	0.382885420672525	684	368090			
SGTC_926	2268-1401	59.4	µM	-0.298735172159712	0.393049489300939	no	2063	0.38257105914194	673	2931578			
SGTC_2648	atorvastatin	78.68	µM	-0.299310880764089	0.392799201347366	no	2064	0.382351426639412	696	60823	Atorvastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YHR007C	ERG11
SGTC_2089	5281248	129.67	µM	-0.29981782082695	0.392578847044726	no	2065	0.382158060626226	664	2737878			
SGTC_1425	4048-4433	7.33	µM	-0.301309804681311	0.391930518609261	no	2066	0.381589132540573	694	23734946			
SGTC_2112	5488546	200	µM	-0.306819766747263	0.389538825588066	no	2067	0.379490280893639	709	600757			
SGTC_788	1182-0090	188	µM	-0.307843530621429	0.389094900937907	no	2068	0.379100698163557	668	5715185			
SGTC_41	0478-0632	82.643	µM	-0.308239680593608	0.388923161132093	no	2069	0.378949980320067	708	3750424			
SGTC_2278	7948257	134.34	µM	-0.308340026819936	0.388879662259331	no	2070	0.378911805863378	698	1247028			
SGTC_1531	st059297	52.4	µM	-0.3111190092996	0.387675562330335	no	2071	0.377855075228743	671	7566702			
SGTC_707	0865-0008	204	µM	-0.312049343083815	0.387272700408695	no	2072	0.377501511936332	681	723043			
SGTC_457	grayanotoxin iii	135	µM	-0.312382466568533	0.387128477620029	no	2073	0.377374936897679	694	46864190	Grayanotoxin III activates Na+ ion channels affecting their polarization state. This produces an effect on the voltage-dependent Ca2+ channels, increasing influx of Ca2+, and leading to subsequent release of GABA and glutamates and presentation of excitotoxicity.		
SGTC_2139	5578692	56.4705	µM	-0.313122292135185	0.386808232607665	no	2074	0.377093876704078	696	650991		YMR113W	FOL3
SGTC_2229	7354935	190	µM	-0.316080703374739	0.385528410397087	no	2075	0.375970626480669	706	318112			
SGTC_2513	baicalein	25.65	µM	-0.317898841658387	0.38474249241441	no	2076	0.375280835641211	710	5281605	Baicalein is a cell-permeable flavone, originally isolated from the roots of Scutellaria baicalensis; inhibits cellular Ca2+ uptake; may also act as an iron chelator.	YIL026C | YBR002C	IRR1 | RER2
SGTC_2331	7980721	200	µM	-0.318092307060315	0.384658891855973	no	2077	0.375207459445947	671	2981221			
SGTC_1059	3448-6867	171	µM	-0.318156728098787	0.384631055330684	no	2078	0.375183027290121	681	3934407			
SGTC_3021	9087658	49.47	µM	-0.318361013491368	0.384542786929876	no	2079	0.375105553854592	687	25237042			
SGTC_2160	5660466	132.927	µM	-0.318744390792943	0.384377151983369	no	2080	0.374960174992755	751	2859134			
SGTC_1512	0259-0544	12.2	µM	-0.319870564966125	0.383890720063807	no	2081	0.374533226121559	657	18476			
SGTC_2066	5222451	176	µM	-0.320262507591375	0.383721469924238	no	2082	0.374384671066281	704	2281147			
SGTC_102	gallobenzophenone	83.616	µM	-0.321320873418045	0.383264553306968	no	2083	0.373983619868216	692	70837			
SGTC_2195	6536160	144.242	µM	-0.321665649040798	0.383115742150233	no	2084	0.373853001958643	672	3834386			
SGTC_1856	st057054	55.7	µM	-0.323195797361363	0.382455511925977	no	2085	0.373273481744054	719	1266018			
SGTC_2989	9073649	71.4286	µM	-0.324192505423918	0.382025634704618	no	2086	0.372896147875279	726	21367202			
SGTC_1304	1165-0502	251	µM	-0.325201504473352	0.381590604517253	no	2087	0.372514285055112	675	767425			
SGTC_1293	1000-1278	195	µM	-0.325276068056922	0.381558462336567	no	2088	0.372486070906818	713	678847			
SGTC_2393	9031399	185.94	µM	-0.325715268120625	0.381369152611846	no	2089	0.372319895685814	716	1526623		YDL150W	RPC53
SGTC_673	1082-0474	110	µM	-0.32631755600179	0.381109592806346	no	2090	0.372092053404323	718	3098046			
SGTC_1680	diphenhydramine	100	µM	-0.326488910776974	0.381035756139653	no	2091	0.37202723898842	716	8980	A first generation anti-histamine possessing anticholinergic, antitussive, antiemetic and sedative properties.	YIL048W	NEO1
SGTC_180	1486-1293	102.781	µM	-0.327758282630974	0.380488919644484	no	2092	0.371547216027969	714	4140536			
SGTC_757	1066-0008	322	µM	-0.328315328094834	0.380249023664807	no	2093	0.37133662789662	692	6842497			
SGTC_3152	9099253	49.47	µM	-0.328890667883394	0.380001297441611	no	2094	0.371119164120032	702	25236131			
SGTC_1744	st037937	38.9	µM	-0.329983403781608	0.379530929634172	no	2095	0.370706251139052	712	1016152			
SGTC_917	harmaline	728.087	nM	-0.330515378622709	0.37930200569989	no	2096	0.370505287232377	681	5280951	Harmaline is a fluorescent psychoactive indole alkaloid family; monoamine oxidase (MAOI)  inhibitor.	YHR072W	ERG7
SGTC_1473	k844-0725	134	µM	-0.330987089997228	0.37909905024555	no	2097	0.370327118582504	665	54682906			
SGTC_462	ag-879	158	µM	-0.331230822459744	0.378994196562162	no	2098	0.370235070041935	713	6809654	Ag-879 is a 5-Lipoxygenase inhibitor.		
SGTC_65	0798-0905	34.986	µM	-0.331361150920852	0.378938132922797	no	2099	0.370185852955987	778	3602145			
SGTC_2170	morpholine	200	µM	-0.332079446533899	0.378629188076426	no	2100	0.369914634808044	695	121171	Reacts with secondary amines.		
SGTC_2841	9004761	38.96	µM	-0.332468752456449	0.378461776792086	no	2101	0.369767665483209	674	2991039			
SGTC_720	r052-1644	49.9	µM	-0.333282557515721	0.378111893968944	no	2102	0.369460502285856	711	1422863		YOR257W	CDC31
SGTC_663	1486-0733	13.9	µM	-0.333768754367989	0.377902908867688	no	2103	0.369277031515689	702	722445		YPR165W	RHO1
SGTC_2591	skatole	100	µM	-0.335667197226657	0.377087231675058	no	2104	0.36856092239907	720	6736	A reactive methylindole and nucleophilic thiol agent. Glutathione protects alkylation of proteins by a skatole metabolite.		
SGTC_836	0330-0104	1.35	µM	-0.336233612089948	0.376843974189995	no	2105	0.368347354053446	676	46494820			
SGTC_1548	st061468	90.8	µM	-0.33918382194675	0.375577743631446	no	2106	0.367235627942433	693	390799			
SGTC_1044	1222-0021	1.78	µM	-0.339574412949288	0.375410201991216	no	2107	0.367088524893889	714	4306703			
SGTC_3066	9117245	49.47	µM	-0.339675567122615	0.375366816351643	no	2108	0.367050431734552	708	17176980			
SGTC_1595	6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin	67.5	µM	-0.34036945689852	0.375069245332906	no	2109	0.366789158452225	690	688788			
SGTC_196	k015-0023	18.111	µM	-0.343768038033277	0.373612858348679	no	2110	0.365510369423182	685	5211998			
SGTC_601	0986-0029	62.9	µM	-0.345083979514429	0.373049423736549	no	2111	0.365015618520438	685	24747981			
SGTC_799	1310-0557	151	µM	-0.345960430137472	0.372674312400315	no	2112	0.364686226362571	733	5354492			
SGTC_779	1360-0071	233	µM	-0.346210019753869	0.372567512827158	no	2113	0.364592442574341	707	7566			
SGTC_2964	9083345	53.42	µM	-0.346263786862955	0.372544507125525	no	2114	0.364572240538268	667	17741579			
SGTC_2647	atorvastatin	60.16	µM	-0.346313306118594	0.372523319384329	no	2115	0.364553634890376	695	60823	Atorvastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YPR034W	ARP7
SGTC_568	1193-0097	7.48	µM	-0.346344528625113	0.372509960448303	no	2116	0.364541903962002	696	3646150			
SGTC_2311	7694451	200	µM	-0.34775611178466	0.371906157561766	no	2117	0.364011676232229	720	2163142			
SGTC_114	0364-0001	490.298	µM	-0.348881657600592	0.371424932348909	no	2118	0.363589078066641	695	4003655			
SGTC_3053	9095903	49.47	µM	-0.348922319386831	0.371407551226504	no	2119	0.363573814268253	731	17174018			
SGTC_2381	9035592	200	µM	-0.34995517198179	0.370966140253752	no	2120	0.363186170237442	709	4749657			
SGTC_3252	9135871	49.47	µM	-0.350160083408687	0.370878587265744	no	2121	0.363109280753625	717	17682838			
SGTC_1983	st071813	46.9	µM	-0.351865120515631	0.370150331658024	no	2122	0.362469709145258	704	11838595			
SGTC_851	0394-0702	453	µM	-0.35230764498988	0.369961396507059	no	2123	0.362303777683662	695	762646			
SGTC_14	0354-0009	295	µM	-0.352479971869525	0.369887830294948	no	2124	0.362239168025687	702	1713507			
SGTC_2657	nystatin	74.44	µM	-0.353359915268749	0.369512257414977	no	2125	0.36190931645034	704	11468707	Nystatin is a polyene antifungal that binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.		
SGTC_3178	9107506	49.47	µM	-0.353650798971424	0.369388131298935	no	2126	0.361800299651835	698	8897194			
SGTC_2242	6630449	61.2675	µM	-0.354132632371272	0.369182552939962	no	2127	0.361619743793211	704	691249		YDR170C	SEC7
SGTC_2828	7998861	71.43	µM	-0.354357789351224	0.369086500601537	no	2128	0.361535382011321	690	2988188			
SGTC_2735	sertaconazole	140	nM	-0.35436230643119	0.369084573691404	no	2129	0.361533689621365	687	65863	A topical antifungal; lanosterol 14-alpha-demethylase inhibitor.	YJL195C	YJL195C
SGTC_1918	oxolan-2-ylmethyl 3-bromobenzoate	70.1	µM	-0.354612032436767	0.368978049908958	no	2130	0.361440130343149	722	551469			
SGTC_1813	st051246	8.6015	µM	-0.354619004137172	0.368975076186429	no	2131	0.361437518530349	687	5291959			
SGTC_2398	5228213	48.84	µM	-0.354958433819449	0.368830304685087	no	2132	0.361310365573149	713	80771		YMR134W	ERG29
SGTC_2032	5185112	25.99	µM	-0.356354896106259	0.368234889997975	no	2133	0.36078740140809	689	5718189			
SGTC_1009	4106-0057	9.87	µM	-0.358560678757524	0.367295047384923	no	2134	0.359961883527153	729	2928005			
SGTC_2164	5685496	200	µM	-0.359043073108588	0.367089613880323	no	2135	0.359781433478531	699	759046			
SGTC_3331	9141060	1.957	µM	-0.359124740267501	0.367054838691259	no	2136	0.359750887202218	703	4906567		YPR165W	RHO1
SGTC_2667	digitoxin	100	µM	-0.359592547919239	0.366855659699894	no	2137	0.359575928606124	675	5702041	Digitonin is a glycoside obtained from Digitalis purpurea; the aglycone is digitogenin, a spirostan steroid. As a detergent, it effectively water-solubilizes lipids. As such, it has several membrane-related applications in biochemistry, including solubilizing membrane proteins, precipitating cholesterol, and permeabilizing cell membranes.		
SGTC_2979	9012552	45.46	µM	-0.35975652692123	0.36678585065578	no	2138	0.359514607937219	704	17100905			
SGTC_1710	st031758	61.5	µM	-0.363248346830253	0.36530036430832	no	2139	0.358209687484138	717	5394341			
SGTC_3022	9087993	49.47	µM	-0.363529957547038	0.365180649445199	no	2140	0.358104519249112	693	17173644			
SGTC_1336	1486-0901	104	µM	-0.363767048230323	0.365079870573439	no	2141	0.358015985480473	683	5006114			
SGTC_3167	9103034	49.47	µM	-0.364127354801795	0.364926734824145	no	2142	0.357881455384507	692	5127859			
SGTC_3121	9125696	49.47	µM	-0.364217381432713	0.364888475505574	no	2143	0.35784784428902	713	1235365			
SGTC_2190	6049624	200	µM	-0.366726018365322	0.363822902818676	no	2144	0.35691169843829	721	2265554			
SGTC_2960	9079389	5.97	µM	-0.367668246697852	0.36342295177815	no	2145	0.356560310024321	715	16457355			
SGTC_1085	doxorubicin	7.67	µM	-0.368261118009091	0.363171369822741	no	2146	0.35633927087927	725	443939	Doxorubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally, doxorubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.	YIL143C	SSL2
SGTC_2390	9097792	176.6	µM	-0.36832758273627	0.363143169527844	no	2147	0.356314493961344	695	4497149			
SGTC_106	0092-0003	11.579	µM	-0.368585356002325	0.363033806022351	no	2148	0.35621840621828	713	1072148			
SGTC_2346	9031566	143.75	µM	-0.368734701526969	0.362970449439941	no	2149	0.356162740252313	712	4771086			
SGTC_951	1171-0579	82.7	µM	-0.370827860743588	0.362082867622424	no	2150	0.355382874336717	708	1616050		YPR165W | YDR526C	RHO1 | YDR526C
SGTC_1750	st081859	2.357	µM	-0.37154891789394	0.361777282420298	no	2151	0.355114363992951	721	5291695			
SGTC_1549	4'-methoxyflavonol	74.6	µM	-0.372068830144905	0.361556997418461	no	2152	0.354920801467953	723	97141			
SGTC_1447	4239-0816	81.9	µM	-0.372165144040235	0.361516194592579	no	2153	0.354884948062978	718	1341554			
SGTC_1903	st060211	78.3	µM	-0.372405017818442	0.361414580297047	no	2154	0.354795659247373	693	688960			
SGTC_1573	oleylamine	1.06	µM	-0.372814667676309	0.361241068795121	no	2155	0.354643192701152	726	5356789	An amine of the fatty acid oleic acid.		
SGTC_3338	9144300	39.5675	µM	-0.373171003697885	0.361090162138525	no	2156	0.354510587831558	712	4901274			
SGTC_2207	7258803	200	µM	-0.37347611622281	0.360960965573959	no	2157	0.354397058995596	728	3666799			
SGTC_1050	3232-1156	69.3	µM	-0.374949692182615	0.360337219473968	no	2158	0.353848940721885	723	700529			
SGTC_1975	st070967	30.8	µM	-0.375260694601018	0.360205623502438	no	2159	0.353733297451367	735	261391			
SGTC_427	1354-0053	47.3	µM	-0.37945036759169	0.358434446854117	no	2160	0.352176727071178	737	6813657			
SGTC_1108	betulinic acid	729.144	nM	-0.381174534857661	0.357706439325042	no	2161	0.351536871776252	690	64945	Apoptosis-inducing agent of unknown mechanism.		
SGTC_3299	9121982	43.1275	µM	-0.381340253307575	0.357636494044406	no	2162	0.351475394160991	718	17594604		YPL160W	CDC60
SGTC_200	k038-0079	37.545	µM	-0.382095887871279	0.357317621741546	no	2163	0.351195120921759	707	3436683			
SGTC_3120	9124077	49.47	µM	-0.38289662265425	0.356979826174787	no	2164	0.350898207812025	717	18774327		YGL155W	CDC43
SGTC_88	0180-0332	8.668	µM	-0.384356788698351	0.356364133645194	no	2165	0.350357011488301	696	3101745			
SGTC_1257	0669-0121	16	µM	-0.38442569242983	0.356335088982527	no	2166	0.350331480486052	698	4307855			
SGTC_2077	5212015	200	µM	-0.385071372778255	0.356062958926104	no	2167	0.350092268459278	724	780900			
SGTC_2635	hydroquinidine	100	µM	-0.386876935629604	0.355302371379343	no	2168	0.349423658427185	708	442912	An experimental heart treatment.		
SGTC_2074	5212007	75.395	µM	-0.388389748466314	0.354665547162596	no	2169	0.348863814756908	698	758611			
SGTC_1568	digitonin	820	nM	-0.388507532010396	0.354615982751363	no	2170	0.348820240616651	750	2735010	Digitonin is a glycoside obtained from Digitalis purpurea. As a detergent, it effectively water-solubilizes lipids and has several membrane-related applications in biochemistry, including solubilizing membrane proteins, precipitating cholesterol, and permeabilizing cell membranes.	YMR211W	DML1
SGTC_2246	7293507	91.5585	µM	-0.388649869713485	0.354556089006186	no	2171	0.348767585301415	741	887656			
SGTC_1523	st012844	44.7	µM	-0.390299166629191	0.353862350156454	no	2172	0.348157669733163	733	4274103			
SGTC_2697	mebhydrolin	72.4	µM	-0.391239212401584	0.353467158311522	no	2173	0.347810213147459	702	22530	H1 Histamine receptor antagonist.	YIL048W	NEO1
SGTC_312	4092-0653	6.84	µM	-0.39135597952771	0.35341808085096	no	2174	0.347767062986904	705	1148278			
SGTC_1171	0368-0077	21.4	µM	-0.391527068902934	0.353346176040241	no	2175	0.347703842126624	696	3239779			
SGTC_1014	4130-3005	69.3	µM	-0.391870762739257	0.353201745485476	no	2176	0.347576853352136	730	743608			
SGTC_1129	3453-1384	223	µM	-0.393946020893256	0.352330109080462	no	2177	0.346810446130539	775	1084452			
SGTC_2560	caryophyllene	100	µM	-0.394037381366469	0.352291754228047	no	2178	0.346776720447275	705	16667688	A peroxisome proliferator-activated receptor (PPAR) inhibitor.		
SGTC_359	0081-0058	15.9	µM	-0.395844247353442	0.351533506848502	no	2179	0.346109966320034	770	3494159			
SGTC_2182	6325192	200	µM	-0.397097474592636	0.351007939293277	no	2180	0.345647791076395	680	736248			
SGTC_829	1635-0120	117	µM	-0.398338809294959	0.35048763995027	no	2181	0.345190228339519	730	285054			
SGTC_2682	pyrogallin	40.03	µM	-0.399159376353243	0.350143857163594	no	2182	0.344887886994854	728	822798	An ATP competetive kinase inhibitor.		
SGTC_2233	sulbentine	40.3845	µM	-0.399652460861318	0.349937334704709	no	2183	0.344706255571062	726	67686	An antifungal agent of unknown mechanism.	YOR207C | YLR033W	RET1 | RSC58
SGTC_1231	0242-0792	125	µM	-0.399758509741075	0.349892923216479	no	2184	0.344667196335808	736	3707635			
SGTC_363	0455-0021	3.06	µM	-0.400138467223903	0.349733820272348	no	2185	0.34452726645802	723	4597466			
SGTC_3245	9134821	49.47	µM	-0.401281125169343	0.349255504136101	no	2186	0.344106579239187	733	17014901			
SGTC_2287	7945887	168.79	µM	-0.401995717148865	0.348956497817105	no	2187	0.343843589120466	702	1245853			
SGTC_2132	5317594	122.667	µM	-0.40274285058923	0.348643975457011	no	2188	0.343568703597408	715	794577			
SGTC_2317	5986382	200	µM	-0.403494113945365	0.348329829108878	no	2189	0.343292381983261	733	877883			
SGTC_795	0685-0265	78	µM	-0.403814294692709	0.348195974752968	no	2190	0.343174641986431	706	302754			
SGTC_2974	9094440	9.66	µM	-0.404080248945255	0.348084804631295	no	2191	0.343076854259643	703	25236134			
SGTC_3132	9126706	49.47	µM	-0.404884656289417	0.347748638085854	no	2192	0.342781148706938	773	850858			
SGTC_1160	4092-0570	10.5	µM	-0.406384198553583	0.347122290201652	no	2193	0.342230164069536	726	4994975			
SGTC_125	0133-0007	11.75	µM	-0.407227183442457	0.346770364706683	no	2194	0.341920569054774	733	26541			
SGTC_2919	7978188	46.38	µM	-0.407740892487575	0.346555968583787	no	2195	0.341731956132981	675	2980291			
SGTC_744	1594-0068	283	µM	-0.4085683448297	0.346210735257196	no	2196	0.341428232599086	709	668392			
SGTC_1892	st058411	7.36	µM	-0.408758939230851	0.346131232710455	no	2197	0.341358287817568	739	3934738			
SGTC_75	0159-0059	199.013	µM	-0.409286895180869	0.345911042127589	no	2198	0.341164565760557	776	5377270			
SGTC_2889	9059656	51.95	µM	-0.410975449736015	0.345207159580537	no	2199	0.340545268287386	721	3949838			
SGTC_1857	st056007	79.3	µM	-0.411021246919705	0.345188076234955	no	2200	0.340528477602806	720	619834			
SGTC_2505	galangin	7.89	µM	-0.411939467575578	0.344805543646801	no	2201	0.340191895832142	737	5281616	Galangin is a flavonoid found in medicinal herbs. An inhibitor of cancer cell proliferation, galangin is used to study mechanisms of genotoxicity.		
SGTC_1776	st049249	45.9	µM	-0.412740944828801	0.344471776210988	no	2202	0.339898211405189	708	1822314			
SGTC_1811	st050069	61.5	µM	-0.412791457242906	0.34445074485835	no	2203	0.339879705449151	728	3877702			
SGTC_3057	9095946	49.47	µM	-0.413582151762695	0.34412159394518	no	2204	0.339590073355293	713	24540043			
SGTC_2769	toremifene	3.73	µM	-0.414031632620445	0.343934536329563	no	2205	0.339425470332071	713	3005573	A first generation selective estrogen receptor modulator (SERM). Like tamoxifen, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.		
SGTC_944	3370-0224	231	µM	-0.41521504865742	0.343442224282578	no	2206	0.338992241684558	710	4580514			
SGTC_685	1278-0033	54.9	µM	-0.415348721224503	0.343386631927865	no	2207	0.338943319780857	716	3590572			
SGTC_2931	9014674	55.67	µM	-0.41562527370683	0.343271628781782	no	2208	0.338842114862699	730	2996810			
SGTC_1180	1193-0155	285	µM	-0.417488644729371	0.342497132814178	no	2209	0.338160514163637	744	2921347			
SGTC_1569	carminic acid	40.6	µM	-0.418681826342525	0.342001543291409	no	2210	0.337724339647957	714	14749	Coloring matter from the insect Coccus cacti L. It is used in foods, pharmaceuticals, toiletries, etc., as a dye, and also has use as a microscopic stain and biological marker.		
SGTC_1453	4237-0541	195	µM	-0.419101588831555	0.341827259052949	no	2211	0.337570944788385	733	739892			
SGTC_342	k048-0088	23.3	µM	-0.419448551714952	0.341683226453544	no	2212	0.337444173639922	687	6820570			
SGTC_2614	arthonioic acid	13.39	µM	-0.421062817629861	0.341013409361279	no	2213	0.336854605945143	736	6710684			
SGTC_3270	9137563	49.47	µM	-0.421305605802483	0.340912711072494	no	2214	0.336765968647094	707	17015724			
SGTC_2228	7354201	200	µM	-0.421380725637626	0.340881556830174	no	2215	0.336738545674574	730	753451			
SGTC_2972	9093619	59.92	µM	-0.421477643734929	0.340841363857745	no	2216	0.336703166390551	703	25236256			
SGTC_2213	7173844	200	µM	-0.422334476929808	0.34048610459337	no	2217	0.336390448229485	722	892728			
SGTC_824	1304-0008	100	µM	-0.42316118173078	0.340143471235031	no	2218	0.336088833262724	710	768245			
SGTC_3024	9090631	49.47	µM	-0.424170943087428	0.339725147900739	no	2219	0.335720575083158	702	25236383			
SGTC_1533	dihydroergotamine mesylate	29.4	µM	-0.424646998878479	0.339527996204107	no	2220	0.335547013058352	751	71171	A 9,10alpha-dihydro derivative of ergotamine. It is used as a vasoconstrictor, specifically for the therapy of migraine disorders. [PubChem] DrugBank Mode of Action: Two theories have been proposed to explain the efficacy of 5-HT<sub>1D</sub> receptor agonists in migraine: 1) activation of 5-HT<sub>1D</sub> receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leads to vasoconstriction, which correlates with the relief of migraine headache and 2) activation of 5-HT<sub>1D</sub> receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.		
SGTC_1266	0828-0227	32.9	µM	-0.42498667066729	0.339387352827488	no	2221	0.335423195817332	723	3913820			
SGTC_853	0419-0306	21	µM	-0.425256611853405	0.339275597824732	no	2222	0.335324809537135	733	762713			
SGTC_3258	9138477	49.47	µM	-0.425382958829385	0.339223295336237	no	2223	0.335278763352518	723	4970355			
SGTC_2243	6634756	200	µM	-0.425431158808943	0.339203343329257	no	2224	0.335261197892395	693	885676			
SGTC_963	1269-2853	151	µM	-0.425823285399878	0.339041042333025	no	2225	0.335118309061847	697	3668223			
SGTC_2869	9037858	32.47	µM	-0.426202086447587	0.33888428513434	no	2226	0.334980298642504	706	27187042			
SGTC_1485	3909-9022	254	µM	-0.428750165378097	0.337830553469044	no	2227	0.33405252450186	736	714516			
SGTC_1260	0700-1617	7.75	µM	-0.428882547853284	0.337775842694611	no	2228	0.334004350716329	700	2853078			
SGTC_1819	st053448	58.6	µM	-0.429508526912279	0.337517185714209	no	2229	0.333776594924313	763	2857616			
SGTC_719	2810-4230	27.3	µM	-0.431245805925996	0.33679973765378	no	2230	0.333144825498727	725	721079			
SGTC_869	0564-0080	44.1	µM	-0.432642576447423	0.336223340381118	no	2231	0.332637226588451	718	6843321			
SGTC_1956	st077085	54	µM	-0.43336575474206	0.335925061645439	no	2232	0.332374537557427	755	24208685			
SGTC_2521	angolensin	13.4	µM	-0.434609798282453	0.335412191063999	no	2233	0.331922840832368	714	821428	A flavenoid.		
SGTC_51	1013-0126	23.419	µM	-0.435502738897572	0.335044255435778	no	2234	0.331598775694081	757	1627850			
SGTC_3314	9135860	59.4275	µM	-0.43589786457281	0.334881494627734	no	2235	0.331455417268841	744	25252478			
SGTC_632	0781-2353	4.65	µM	-0.436094832394839	0.334800370903702	no	2236	0.331383963158303	734	6811515		YHR007C	ERG11
SGTC_2805	7950783	58.44	µM	-0.436687752361861	0.334556215753863	no	2237	0.331168906353433	716	1178958		YDL195W	SEC31
SGTC_1215	3852-0577	11.2	µM	-0.436794985283131	0.334512066383788	no	2238	0.331130018060297	714	2884876			
SGTC_682	0kpi-0099	17	µM	-0.437250444267875	0.334324572731604	no	2239	0.330964864996814	743	1714895		YML126C	ERG13
SGTC_1028	k015-0029	4.8	µM	-0.437897748633578	0.334058175367226	no	2240	0.330730203856422	744	4588309			
SGTC_613	3914-0030	117	µM	-0.4395744682683	0.333368512284964	no	2241	0.330122667966831	710	1145395			
SGTC_2987	9018338	71.43	µM	-0.439896650775642	0.333236057585448	no	2242	0.330005980870707	746	5055682			
SGTC_1815	st051655	58.2	µM	-0.441003369731121	0.332781225124613	no	2243	0.329605278737652	738	5984156			
SGTC_1477	0139-0234	16	µM	-0.441670728950151	0.332507076828098	no	2244	0.329363747040289	729	620880			
SGTC_1154	4088-0362	150	µM	-0.441842060342758	0.332436709072015	no	2245	0.329301749993019	740	6618304			
SGTC_297	0986-0032	24	µM	-0.441949432397678	0.332392613154881	no	2246	0.329262899316394	750	2847425			
SGTC_615	k087-0205	167	µM	-0.442300464633601	0.332248466245917	no	2247	0.329135897385897	740	9642773			
SGTC_1729	st035615	45.989	µM	-0.442337954123135	0.332233073131512	no	2248	0.329122335017337	730	17385451			
SGTC_2111	5486399	200	µM	-0.44243914020084	0.332191527729881	no	2249	0.329085730603549	729	689674			
SGTC_2961	9083290	32.55	µM	-0.442467454815533	0.332179902566602	no	2250	0.329075487987115	749	17741490			
SGTC_2477	5967686	25.23	µM	-0.442559268624326	0.332142207578513	no	2251	0.329042275858207	731	776118			
SGTC_3339	9145883	14.936	µM	-0.445819451713426	0.33080481329976	no	2252	0.327863834864021	759	2030670			
SGTC_567	1080-0542	68.4	µM	-0.445843746407747	0.33079485519091	no	2253	0.327855059602734	713	5950415			
SGTC_2677	mitomycin C	100	µM	-0.445850512388494	0.330792081916467	no	2254	0.327852615742481	737	5746	Mitomycin is a bifunctional and trifunctional alkylating agent, cross-links DNA inhibiting DNA synthesis and function. Mitomycin is cell cycle phase-nonspecific.		
SGTC_2519	cryptotanshinone	88.04	µM	-0.446712100124217	0.330439005909182	no	2255	0.327541472052449	745	160254	Cryptotanshinone is a natural product that exhibits antitumor activity via inhibition STAT3 activity. Displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE)		
SGTC_735	3076-0345	636	µM	-0.446987285549187	0.330326267543101	no	2256	0.327442120034199	718	2888990			
SGTC_1127	asiatic acid	681.4	nM	-0.450157681992166	0.329028527833614	no	2257	0.326298373695338	731	470603	A kinase inhibitor which arrests cells at G2/M.		
SGTC_892	0929-0076	29	µM	-0.450270015714803	0.328982583885436	no	2258	0.32625787825762	702	5751038			
SGTC_686	1319-0111	510	µM	-0.450516129023539	0.328881933766502	no	2259	0.32616916347452	786	4562600			
SGTC_2290	7904846	200	µM	-0.450705722026428	0.328804406564924	no	2260	0.326100828886809	719	2962154			
SGTC_2529	gangaleoidin	93.61	µM	-0.450718120946374	0.328799336731619	no	2261	0.326096360174843	748	4565183			
SGTC_1163	k060-0048	49.9	µM	-0.45110170855389	0.32864250595804	no	2262	0.325958123172132	715	6809982			
SGTC_1255	0566-0045	221	µM	-0.451909813266063	0.328312209060493	no	2263	0.32566697731657	739	2788469			
SGTC_3049	9092223	49.47	µM	-0.45253461442176	0.328056925829665	no	2264	0.32544194535653	758	8623917			
SGTC_3333	9141820	12.094	µM	-0.453678007886434	0.327589962510961	no	2265	0.325030299008559	731	1939433			
SGTC_2681	menadione	3.18	µM	-0.453992200919784	0.32746169286557	no	2266	0.324917220101741	744	4055	Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. As a free radical generator, menadione is often used as a research tool to induce oxidative stress.		
SGTC_1992	st073643	23.3	µM	-0.45451112795103	0.327249884944518	no	2267	0.324730492206975	754	3161292			
SGTC_2589	lobaric acid	100	µM	-0.455158151925933	0.326985870220862	no	2268	0.324497732288992	733	73157	A novel microtubule depolymerizer.		
SGTC_1736	st036774	51	µM	-0.455655189309182	0.326783115522531	no	2269	0.324318974977912	776	1272247			
SGTC_918	glabranin	770.725	nM	-0.457493829297076	0.326033530485232	no	2270	0.32365806829496	738	124049	Also referred to as licorice root.		
SGTC_2060	5238662	140	µM	-0.458291850009741	0.325708408222433	no	2271	0.323371389309453	759	790130			
SGTC_674	0498-0004	451	µM	-0.459445912791926	0.325238465018984	no	2272	0.322956992103974	729	4231473			
SGTC_2358	9037157	4	µM	-0.460590330095109	0.324772723832038	no	2273	0.322546275286402	752	2388925			
SGTC_2356	9061756	188.97	µM	-0.462800735807326	0.323873935107354	no	2274	0.321753601887345	711	20104043			
SGTC_3067	9117431	49.47	µM	-0.463938579875488	0.323411667917466	no	2275	0.321345875517558	756	17150885			
SGTC_2923	7992654	58.14	µM	-0.464801903919866	0.323061110568632	no	2276	0.321036662106799	716	2985126			
SGTC_2613	3',4'-dimethoxydalbergione	24.65	µM	-0.464916302515792	0.323014670188005	no	2277	0.320995697711629	724	115019			
SGTC_731	3966-0296	387	µM	-0.465151275757902	0.322919290898454	no	2278	0.32091156420542	729	660956			
SGTC_2658	polymyxin b sulfate	77.05	µM	-0.467688712026529	0.32189004906084	no	2279	0.32000360726162	739	5702105	Polymyxin B (PMB) acts selectively on Gram-negative bacteria by electrostatic and hydrophobic interactions with anionic cell envelope components such as phospholipids and lipopolysaccharides. 	YIL048W	NEO1
SGTC_1810	st050138	53	µM	-0.467712763982269	0.321880299559188	no	2280	0.319995006026688	780	3444541			
SGTC_2860	9025725	38.96	µM	-0.469536645121732	0.321141343804293	no	2281	0.31934304889846	771	40546248			
SGTC_2008	4012253	172	µM	-0.470423859295539	0.320782139618807	no	2282	0.319026110593201	724	603940			
SGTC_393	acivicin	6.25	µM	-0.471516629296265	0.320339943084301	no	2283	0.318635923644755	746	16758175	Acivicin is a glutamine analog antimetabolite, used as an antineoplastic agent. It interferes with glutamate metabolism and inhibits glutamate dependent synthesis of enzymes, and is thereby potentially helpful in treatment of solid tumors. is an irreversible inhibitor of γ-glutamyl transpeptidase.	YPR035W	GLN1
SGTC_905	2-aminofluorene	215	µM	-0.474975183742809	0.318942099260964	no	2284	0.317402330770098	729	1539	An established DNA mutagen.	YPR165W	RHO1
SGTC_316	k060-0003	58.6	µM	-0.474983864684359	0.318938593912243	no	2285	0.317399237005429	756	6152314			
SGTC_3092	9117248	49.47	µM	-0.475743696203454	0.318631838073293	no	2286	0.31712849325326	748	17141857			
SGTC_2193	5925765	200	µM	-0.476557973291754	0.318303239634084	no	2287	0.316838458037834	744	877370			
SGTC_832	4083-0019	164	µM	-0.47743250120896	0.317950486366909	no	2288	0.316527087565821	761	1990758			
SGTC_194	1486-1323	56.904	µM	-0.4775524895	0.31790210025866	no	2289	0.316484376583339	754	5178754			
SGTC_1692	fluoroquinolonic acid	71	µM	-0.477977685002919	0.317730662263328	no	2290	0.316333043873145	767	483180	Also called cipro. Inhibits gyrases and topoisomerase 1 and 2		
SGTC_1611	st001856	99.4	µM	-0.478946468411999	0.317340196653603	no	2291	0.315988355920006	779	647478			
SGTC_1428	4049-0204	61.7	µM	-0.479130750888458	0.317265945074782	no	2292	0.315922807293968	763	X1428			
SGTC_2460	5552655	174.22	µM	-0.479258604294062	0.317214434366266	no	2293	0.315877333689518	756	5401989			
SGTC_2877	9040724	71.43	µM	-0.479823249658257	0.316986987418825	no	2294	0.315676539677584	758	6463895			
SGTC_1480	1070-0044	41.2	µM	-0.480370983588208	0.31676641868768	no	2295	0.315481811528967	737	3124987			
SGTC_3097	9117246	49.47	µM	-0.480710920722662	0.316629561058016	no	2296	0.315360984215887	733	16423892			
SGTC_2726	cimetidine	79.27	µM	-0.482906837083169	0.315746097378647	no	2297	0.314580943491303	765	2756	A P450 inhibitor, histamine H2-receptor antagonist.		
SGTC_3008	9078912	71.4286	µM	-0.484241682712256	0.315209574292436	no	2298	0.314107179017259	768	16648731			
SGTC_2083	5306046	65.942	µM	-0.484734050811222	0.315011771894422	no	2299	0.313932504591329	764	539837			
SGTC_550	4123-0385	25.7	µM	-0.485179658563962	0.31483280057041	no	2300	0.313774454981199	771	5731123			
SGTC_2718	lomofungin	53.02	µM	-0.485180327640665	0.314832531878988	no	2301	0.313774217696576	761	5351222	A RNA synthesis inhibitor.		
SGTC_2821	7996764	71.43	µM	-0.485827846002854	0.314572543939647	no	2302	0.313544614750422	704	2987135			
SGTC_2527	2',3'-dihydroxy-4-methoxy-4'-ethoxybenzophenone	63.64	µM	-0.486173263159568	0.314433891566882	no	2303	0.313422163128369	794	6728940			
SGTC_3084	9116877	49.47	µM	-0.486218782296633	0.314415621882766	no	2304	0.313406027963995	774	27241325			
SGTC_1056	3448-1962	115	µM	-0.486352628862871	0.314361903495854	no	2305	0.313358585452757	748	715507			
SGTC_162	k030-0015	37.8	µM	-0.487946979055831	0.313722324705585	no	2306	0.312793698600307	763	1809920		YMR134W	ERG29
SGTC_1232	0279-0259	161	µM	-0.489218059036393	0.313212827464182	no	2307	0.312343662783244	749	1560000			
SGTC_1000	4048-0884	8.67	µM	-0.490337673887018	0.31276433834509	no	2308	0.311947486104725	770	13040088			
SGTC_430	0958-0115	16.4	µM	-0.491119371158021	0.312451374562743	no	2309	0.311671010731701	744	6833180			
SGTC_643	k048-0106	28.4	µM	-0.491725248920836	0.312208895665166	no	2310	0.31145679325056	749	6763920			
SGTC_1688	st021091	57.6	µM	-0.49182974383978	0.312167083876762	no	2311	0.311419853901201	778	3656366			
SGTC_2587	piperic acid	92.2	µM	-0.493316983364727	0.311572253821814	no	2312	0.310894315033668	758	5370536			
SGTC_433	pimozide	108	µM	-0.49472670150882	0.311008882466742	no	2313	0.310396525343275	752	16362	D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7receptor; Ca2+ channel antagonist; antipsychotic		
SGTC_1795	st049545	62.3	µM	-0.495637871367323	0.31064498336657	no	2314	0.310074964097708	721	5291882			
SGTC_3227	9130768	49.47	µM	-0.496234890282511	0.310406648914108	no	2315	0.309864348680042	766	17720899			
SGTC_165	k038-0023	64.381	µM	-0.49656160617515	0.310276255151924	no	2316	0.309749116757369	751	46368543			
SGTC_2085	5307070	144.047	µM	-0.497835331484582	0.309768133549593	no	2317	0.309300055433406	780	2840351			
SGTC_1212	0520-0165	585	µM	-0.498031649830251	0.30968984942649	no	2318	0.309230867246455	817	5403258			
SGTC_2028	5153890	36.43	µM	-0.499097862835012	0.309264835949104	no	2319	0.308855221541661	769	2830968		YPR165W	RHO1
SGTC_3341	9147222	25.867	µM	-0.500508509663744	0.308702916417154	no	2320	0.308358532870289	776	1939759			
SGTC_103	0844-0104	51.839	µM	-0.501165899336783	0.308441203477564	no	2321	0.308127185707188	764	5375804			
SGTC_2604	4'-hydroxychalcone	11.32	µM	-0.501280069314954	0.308395761261903	no	2322	0.308087015018166	761	5282362			
SGTC_1236	0330-0013	258	µM	-0.50209543269426	0.308071313697895	no	2323	0.307800196399756	767	4617066			
SGTC_785	1270-0111	65.3	µM	-0.502502967972035	0.307909204357597	no	2324	0.307656882587318	733	6741994			
SGTC_2264	7948757	110.76	µM	-0.503155669050472	0.307649651084261	no	2325	0.307427414939909	766	2971411			
SGTC_2325	6158266	200	µM	-0.503690306736916	0.30743711862913	no	2326	0.307239510525148	736	3623240			
SGTC_3275	9138069	49.47	µM	-0.504018698208102	0.307306606474161	no	2327	0.307124118737185	770	17617007			
SGTC_30	5-(2-thienylidene)-Rhodanine	28.7	µM	-0.504947719934068	0.306937518880794	no	2328	0.306797778042685	760	1241132	A phosphatase inhibitor.		
SGTC_423	5-fluorouracil	457	µM	-0.505430164088882	0.306745927564304	no	2329	0.306628368570157	758	3385	5-fluorouracil (5-FU) is a potent FDA-approved antitumor agent. 5-FU is a pyrimidine analog that inhibits thymidylate synthase and is metabolized into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition to being incorporated in DNA and RNA, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex.		
SGTC_1863	st057641	20.1	µM	-0.505761635887189	0.306614321946774	no	2330	0.306511996729256	773	3921635			
SGTC_1227	3909-8010	46.6	µM	-0.506511434199153	0.306316718425596	no	2331	0.306248832414953	758	15982272			
SGTC_2626	ethyl orsellinate	100	µM	-0.50882502464324	0.305399233709109	no	2332	0.305437438470793	768	75653	A natural product.		
SGTC_1848	st056003	16.4	µM	-0.511855509624577	0.304199302464267	no	2333	0.304376068757603	748	146492			
SGTC_650	1328-0195	38	µM	-0.512504703262881	0.30394252534157	no	2334	0.304148914744457	789	2780821			
SGTC_179	1273-0063	6.77	µM	-0.512603257947787	0.303903552221183	no	2335	0.304114436889046	794	3108139			
SGTC_1218	1348-1416	30.7	µM	-0.513251663402687	0.303647198039952	no	2336	0.303887645553828	755	6787668			
SGTC_1248	0469-0687	58.6	µM	-0.514149038384241	0.303292570378565	no	2337	0.303573897203918	767	4017482			
SGTC_516	3992-2719	87.3	µM	-0.514344078187955	0.303215518391244	no	2338	0.303505724764871	734	5350887		YDR037W	KRS1
SGTC_1470	k295-0292	231	µM	-0.515157093755899	0.302894424613882	no	2339	0.303221624386183	774	5045612			
SGTC_3117	9124945	49.47	µM	-0.515425287362592	0.302788537163873	no	2340	0.303127932827934	761	17592065			
SGTC_2990	9074105	71.4286	µM	-0.515782740795686	0.302647434176395	no	2341	0.303003079108215	780	6502001			
SGTC_1002	4049-0206	172	µM	-0.516280871817991	0.302450848555698	no	2342	0.302829126971318	765	4662749			
SGTC_2395	5646831	180.19	µM	-0.517393694678137	0.302011883983052	no	2343	0.302440680171274	795	6808628			
SGTC_1412	3909-8563	178	µM	-0.517535100188328	0.301956125601696	no	2344	0.302391336550804	775	23767530			
SGTC_3093	9117344	49.47	µM	-0.518654404650793	0.301514929805522	no	2345	0.302000881405429	733	24824913			
SGTC_704	1310-0270	142	µM	-0.519782844855794	0.301070426836551	no	2346	0.301607468761141	793	5718033			
SGTC_644	1498-1197	63.3	µM	-0.520040795370722	0.300968859244575	no	2347	0.301517570816513	766	6741615			
SGTC_3223	9129970	49.47	µM	-0.520403073892844	0.300826238761491	no	2348	0.301391334036956	754	17248386			
SGTC_1774	st048371	48.465	µM	-0.520716182160202	0.300703000011188	no	2349	0.301282249916326	764	4242727			
SGTC_2055	5235184	200	µM	-0.521826782265058	0.300266054024047	no	2350	0.300895470234425	809	2836034			
SGTC_1214	0358-0031	63.7	µM	-0.522501152610177	0.300000875052438	no	2351	0.300660722073929	787	4301366			
SGTC_2903	5923464	63.88	µM	-0.52292218812568	0.299835367303817	no	2352	0.300514201639008	780	2876576			
SGTC_2444	5485484	36.41	µM	-0.525047178393309	0.299000671839805	no	2353	0.299775197251833	788	6790631			
SGTC_1860	st056228	74.6	µM	-0.525417239050692	0.298855420087415	no	2354	0.299646586044447	803	688679			
SGTC_3146	9095609	49.47	µM	-0.526646210177855	0.298373269340198	no	2355	0.299219647811193	759	17173999			
SGTC_1443	4112-3303	14	µM	-0.52733437444206	0.298103443015622	no	2356	0.298980703711041	781	704433			
SGTC_2216	7189485	200	µM	-0.528581777451721	0.297614625139844	no	2357	0.298547802032493	760	731273			
SGTC_2485	5633444	17.78	µM	-0.529086491245516	0.297416947739248	no	2358	0.298372726024332	754	5724239			
SGTC_2563	tomatine	8.54	µM	-0.532191844018804	0.296202019685879	no	2359	0.29729656560574	824	6708777	Tomatine is a toxic glycoalkaloid found in the stems and leaves of tomato plants with fungicidal properties.		
SGTC_2224	6650123	117.647	µM	-0.532241269091679	0.296182701200491	no	2360	0.297279451687259	767	2908370			
SGTC_1295	1013-0063	9.78	µM	-0.533546669727652	0.295672676368642	no	2361	0.296827606914375	773	6826038			
SGTC_439	amiodarone	34.4	µM	-0.533561673007548	0.295666816878906	no	2362	0.296822415582555	761	2157	Amiodarone is a non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ inSaccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.	YIL048W | YNL267W	NEO1 | PIK1
SGTC_1086	cerivastatin	2.18	µM	-0.533968254820931	0.295508047793178	no	2363	0.296681748762587	756	23663992	Cerevastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Cerivastatin was withdrawn from the market due to reports of fatal rhabdomyolysis.	YPR034W	ARP7
SGTC_2291	7917025	104.35	µM	-0.534424026336572	0.295330116886696	no	2364	0.296524099875897	769	2964612			
SGTC_681	1642-0006	26.6	µM	-0.534683862646886	0.295228700167862	no	2365	0.296434241092738	792	4446530			
SGTC_411	enrofloxacin	100	µM	-0.535414975806675	0.294943425418837	no	2366	0.296181468369083	772	71188	A bacterial gyrase inhibitor.		
SGTC_1947	st076332	61.6	µM	-0.537599999545887	0.294091603920506	no	2367	0.295426615273404	783	24208416			
SGTC_3166	9102297	49.47	µM	-0.537653765524182	0.29407065784077	no	2368	0.295408052075234	775	25237072			
SGTC_2949	9072542	2.23	µM	-0.538851700025014	0.293604147023574	no	2369	0.294994593418573	800	16457352			
SGTC_513	4245-1575	41.7	µM	-0.538952472168453	0.293564919025078	no	2370	0.294959824783132	776	719745			
SGTC_1438	4092-1045	4	µM	-0.539317364866263	0.29342289600915	no	2371	0.294833944469408	778	1351342			
SGTC_765	1319-0117	244	µM	-0.539375559940788	0.293400248348593	no	2372	0.294813870681407	753	3487746		YGL099W	LSG1
SGTC_1324	1418-0026	34.4	µM	-0.539485200585694	0.293357581918908	no	2373	0.29477605298877	785	1372513			
SGTC_2024	5144227	134	µM	-0.540444034632552	0.292984576210775	no	2374	0.29444542344109	759	3475211			
SGTC_2153	5569715	200	µM	-0.540617513327071	0.292917113029319	no	2375	0.294385622015451	761	2054701			
SGTC_1226	3909-7979	35.4	µM	-0.541162638479341	0.292705169222474	no	2376	0.294197743449859	779	6615510			
SGTC_3141	9094609	49.47	µM	-0.542128993638263	0.292329626994097	no	2377	0.293864823266961	782	25236309		YDL196W	YDL196W
SGTC_2295	7971645	200	µM	-0.542259947448962	0.29227875333656	no	2378	0.293819721622188	761	2978226		YKL099C	UTP11
SGTC_1553	gossypol	38.6	µM	-0.542800731798492	0.292068710083438	no	2379	0.29363350465981	772	3503	Gossypol is a phenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.		
SGTC_1862	st057513	3.81	µM	-0.542815451212758	0.292062993974215	no	2380	0.293628436851311	779	5393163			
SGTC_637	1181-0519	7.26	µM	-0.543069171682789	0.291964472837381	no	2381	0.293541088737975	772	6252091		YGR060W	ERG25
SGTC_2360	9040895	200	µM	-0.543745589673642	0.291701891443244	no	2382	0.293308277758534	763	4914414			
SGTC_901	1112-0062	60.1	µM	-0.544488900082139	0.291413469810447	no	2383	0.293052542337813	768	1908457			
SGTC_2069	5228469	200	µM	-0.549321815454065	0.289541439674769	no	2384	0.291392309374703	797	2835210			
SGTC_293	4049-0273	38.5	µM	-0.552965167303209	0.288133930863803	no	2385	0.290143631110452	780	1380311			
SGTC_1184	1269-1718	139	µM	-0.553155064511866	0.288060657903486	no	2386	0.290078616849926	768	5403821			
SGTC_1287	0971-0001	34.6	µM	-0.55345045111416	0.287946698719212	no	2387	0.289977500229544	762	4665869			
SGTC_2234	tolnaftate	200	µM	-0.553891903762155	0.287776427419708	no	2388	0.289826413152988	786	5510	Tolnaftate prevents ergosterol biosynthesis by inhibiting squalene epoxidase.	YAR007C | YGR099W | YAL001C | YER082C	RFA1 | TEL2 | TFC3 | UTP7
SGTC_2848	9016370	25.97	µM	-0.555445435468472	0.287177598176594	no	2389	0.289295011114774	771	7894410			
SGTC_3309	9129340	25.759	µM	-0.557145168851387	0.286523090108684	no	2390	0.288714124352618	772	17158987			
SGTC_451	chloral hydrate	100	µM	-0.557650493771085	0.286328643661094	no	2391	0.288541534684601	807	2707	Chloral hydrate is an aldehyde dehydrogenase (ALDH) inhibitor.	YLR153C | YPL028W | YPR107C	ACS2 | ERG10 | YTH1
SGTC_1381	2324-0066	62.1	µM	-0.557706167059491	0.286307224695861	no	2392	0.288522522893391	804	10885928			
SGTC_1608	st001473	40.5	µM	-0.559756147108666	0.285519074135225	no	2393	0.287822889528503	808	7292267			
SGTC_306	1672-3436	11.6	µM	-0.561608141260449	0.284807931914954	no	2394	0.287191516162478	812	6797378			
SGTC_1330	1469-0054	61.8	µM	-0.562462735470583	0.284480063827111	no	2395	0.286900393040511	788	7102664			
SGTC_89	0302-0250	142.109	µM	-0.562731021666492	0.284377172078533	no	2396	0.286809028435773	796	4203518		YLR208W	SEC13
SGTC_3180	9109287	49.47	µM	-0.562845080916362	0.284333434046736	no	2397	0.286770189846543	769	18891271			
SGTC_2059	5238311	157	µM	-0.564361086314891	0.283752400594319	no	2398	0.286254208140859	779	703021			
SGTC_2500	5-alpha-androstan-3,17-dione	61.44	µM	-0.564484336189756	0.283705188099209	no	2399	0.286212278677378	810	6710655			
SGTC_611	3453-1652	23.7	µM	-0.564503553686183	0.283697826922018	no	2400	0.286205741170404	801	1560575			
SGTC_234	nsc-17383	10.7	µM	-0.564897631881376	0.283546897183177	no	2401	0.286071697259819	778	408974			
SGTC_2537	larixol	68.93	µM	-0.56507001884756	0.2834808860409	no	2402	0.286013069995038	775	6708759			
SGTC_2724	maprotiline	69.64	µM	-0.565170267707793	0.283442501713004	no	2403	0.285978978880649	783	4011	A tricyclic antidepressant.		
SGTC_2781	5567276	71.43	µM	-0.565985891163671	0.283130299934488	no	2404	0.2857016858101	796	2853274			
SGTC_109	0132-0036	33.701	µM	-0.566156397088568	0.283065055072348	no	2405	0.285643733916707	732	67274	A color developer.		
SGTC_1964	st076914	61	µM	-0.566387359400841	0.282976687809762	no	2406	0.285565242907007	803	24208661			
SGTC_174	3553-0389	74.3	µM	-0.568374844823732	0.282216814427264	no	2407	0.284890233781681	759	738071			
SGTC_1683	st010134	710	nM	-0.568754468709276	0.282071784976609	no	2408	0.284761388854553	806	3818134			
SGTC_3320	9137005	35.139	µM	-0.569472434669685	0.281797595314054	no	2409	0.284517786171281	784	4908713			
SGTC_1883	5-benzylidenerhodanine	20	µM	-0.57027117504294	0.281492709103326	no	2410	0.284246894104167	786	1273210			
SGTC_1042	0350-0096	82	µM	-0.570445966212434	0.281426011009187	no	2411	0.284187630286608	769	3122515			
SGTC_452	diindolylmethane	8	µM	-0.570790814905363	0.281294443489213	no	2412	0.284070724947574	784	3071	Inhibits expression of several cancer promoting factors.		
SGTC_3135	9127742	49.47	µM	-0.571312506935163	0.281095462721707	no	2413	0.283893912616797	782	3643468			
SGTC_624	k048-0052	28	µM	-0.571849458918211	0.280890732623721	no	2414	0.283711983394647	776	6835531			
SGTC_330	1488-0319	80.1	µM	-0.572054025789667	0.280812753934202	no	2415	0.283642687061667	783	6846614			
SGTC_78	0336-0123	156.75	µM	-0.572216136196852	0.280750966626778	no	2416	0.283587778470736	788	6765896			
SGTC_2227	7312221	64.1025	µM	-0.57247305433974	0.280653057448159	no	2417	0.283500767881981	806	887188		YOR168W | YOR169C	GLN4 | YOR169C
SGTC_1926	methyl fluorone black	53.6	µM	-0.573648287244398	0.280205397547128	no	2418	0.283102914406434	763	72721	Reacts with homocysteine.		
SGTC_590	k048-0076	22.4	µM	-0.574065564620678	0.280046534996393	no	2419	0.282961717311911	797	6832814			
SGTC_2571	chrysanthemic acid	100	µM	-0.577534181081529	0.278727683183207	no	2420	0.281789327564442	822	2743	An insecticide.		
SGTC_809	3998-0021	90	µM	-0.578160477257434	0.278489872890387	no	2421	0.281577889720832	803	715485			
SGTC_1313	1220-0047	237	µM	-0.578222879282826	0.278466183696149	no	2422	0.281556826964221	781	3528706			
SGTC_1323	1348-1351	11.2	µM	-0.580053183001706	0.277771796824204	no	2423	0.280939376933612	792	6989654			
SGTC_2883	9059145	45.46	µM	-0.580874659649931	0.27746041735072	no	2424	0.280662466038133	814	16476510			
SGTC_139	0099-0334	718.624	µM	-0.580929609923054	0.277439594623049	no	2425	0.280643947607755	796	97690			
SGTC_1850	st056238	17	µM	-0.581061397179349	0.277389658582265	no	2426	0.280599537259707	800	5393177			
SGTC_2515	chrysin	20.77	µM	-0.5828438577328	0.27671469124997	no	2427	0.279999208780301	772	5281607	Chrysin is a naturally occurring flavone and aromatase inhibitor.		
SGTC_978	1416-0512	87.4	µM	-0.583372703903697	0.276514587090905	no	2428	0.279821214498896	806	6814003			
SGTC_1373	2887-0003	58.5	µM	-0.583600669824571	0.276428351515973	no	2429	0.279744504715337	794	776948			
SGTC_3284	9108171	64.8615	µM	-0.585130495451339	0.275849986352072	no	2430	0.279229987572591	787	8687505			
SGTC_2473	5854593	8.94	µM	-0.586542201927773	0.275316805260446	no	2431	0.278755605139576	804	2872951			
SGTC_2128	5255449	168.493	µM	-0.588287872457594	0.274658192941548	no	2432	0.27816954219997	775	736008			
SGTC_3204	9114183	49.47	µM	-0.588494690292711	0.274580215541395	no	2433	0.278100148388068	768	17027248			
SGTC_31	0508-1974	57.237	µM	-0.589400474888357	0.274238832465312	no	2434	0.277796329019772	770	6810525			
SGTC_2853	9015042	58.44	µM	-0.589970007696847	0.274024287421884	no	2435	0.277605378658317	783	6457456			
SGTC_1922	5578187	25	µM	-0.590073899125184	0.273985160096743	no	2436	0.277570553331322	774	1350412			
SGTC_235	0330-0087	5	mM	-0.590462580112951	0.273838800547012	no	2437	0.277440282957455	780	46494818		YHR062C	RPP1
SGTC_15	0266-0086	27.098	µM	-0.594066867656454	0.272483434344134	no	2438	0.276233695025946	817	1712902		YIL048W	NEO1
SGTC_2053	5265679	138	µM	-0.594241204683485	0.272417960725743	no	2439	0.276175398510666	808	764595			
SGTC_1003	4049-0218	100	µM	-0.594651201206119	0.272264014164264	no	2440	0.276038323678561	806	295161			
SGTC_627	1391-0720	175	µM	-0.594702480235213	0.27224476282291	no	2441	0.276021181824596	820	997839			
SGTC_2850	9015429	58.44	µM	-0.595165976462967	0.272070786243868	no	2442	0.275866265312628	816	6457570			
SGTC_1899	st063254	59.6	µM	-0.595875851239522	0.271804436948929	no	2443	0.275629083388919	795	3093813			
SGTC_2980	9014342	25.29	µM	-0.596200923857655	0.271682511071816	no	2444	0.275520504262599	806	2996599			
SGTC_2448	5185112	27.17	µM	-0.596400491335311	0.271607672242223	no	2445	0.275453856157754	771	5718189			
SGTC_381	3461-2219	42.7	µM	-0.596755307714145	0.271474639631116	no	2446	0.275335380291296	817	2883159			
SGTC_957	1187-1561	14.1	µM	-0.599337582122129	0.270507436762606	no	2447	0.274473895539471	799	1538454			
SGTC_872	0588-0139	234	µM	-0.600388291748152	0.270114381976835	no	2448	0.2741237444607	779	2047100			
SGTC_2414	st077232	92.9	µM	-0.600723459362564	0.269989060905632	no	2449	0.274012095627	778	729801			
SGTC_960	1222-0186	7.7	µM	-0.601430767800997	0.2697246897979	no	2450	0.273776555464645	807	3126296			
SGTC_2050	5263056	171	µM	-0.601533415201481	0.26968633399211	no	2451	0.273742381266047	786	763468		YGL055W	OLE1
SGTC_410	α-linolenic acid	100	µM	-0.60437151402493	0.268626917264411	no	2452	0.272798335076526	799	860	Alpha-linolenic acid (ALA) is a polyunsaturated n−3 (omega-3) fatty acid. ALA has been noted to be a reactive oxygen species scavenger that temporarily improves cell proliferation.		
SGTC_1310	1188-0297	994	nM	-0.606090582398306	0.267986235244325	no	2453	0.272227302158608	797	1588352			
SGTC_244	nsc-207895	1.295	µM	-0.609589923874534	0.266684442283417	no	2454	0.271066744001214	780	42640			
SGTC_3268	9137683	49.47	µM	-0.609734605328052	0.266630688111425	no	2455	0.271018813509061	850	1953228			
SGTC_3037	9091026	49.47	µM	-0.611134722491273	0.266110779258163	no	2456	0.270555197160034	802	25236398		YIL048W	NEO1
SGTC_2700	st077718	96.8	µM	-0.612585311083944	0.265572670723356	no	2457	0.270075286601141	793	904970			
SGTC_1472	k841-0093	193	µM	-0.613012225214751	0.2654144083722	no	2458	0.269934128126745	819	X1472			
SGTC_1747	st037496	66.6	µM	-0.613291939253843	0.265310740874465	no	2459	0.269841661154946	818	723305			
SGTC_2750	bromebric acid	70.15	µM	-0.615201953451221	0.264603402028653	no	2460	0.269210678943694	799	5358572	An antineoplastic and ion channel blocker.	YOR256C	TRE2
SGTC_207	4185-0010	4.486	µM	-0.615222027817434	0.264595972951425	no	2461	0.269204051214383	800	3761753			
SGTC_714	4296-0578	26.1	µM	-0.61704458899577	0.263921925948958	no	2462	0.26860265782061	802	1589775			
SGTC_157	1348-1695	65.819	µM	-0.618465221217131	0.263397134051072	no	2463	0.268134358281868	790	5380510			
SGTC_261	5-fluorouridine	15.376	µM	-0.619447612832351	0.263034543264253	no	2464	0.267810761596785	785	1821	5-fluorouridine (FUrd) is FDA-approved anticancer drug. As a 5-fluorauracil metabolite, FUrd is thought to also act by inhibiting thymidylate synthetase and through metabolism into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition to being incorporated in DNA and RNA, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex.		
SGTC_1929	genistein trimethyl ether	50.5	µM	-0.619481809576671	0.263021926188699	no	2465	0.267799500842069	801	136420			
SGTC_360	0957-0399	1.01	µM	-0.619776623578044	0.262913165782895	no	2466	0.267702430495772	809	6752301		YPR165W	RHO1
SGTC_803	4488-1585	147	µM	-0.621201134601374	0.262387970814172	no	2467	0.267233646507695	791	747204			
SGTC_1817	st052116	64.4	µM	-0.62152633276784	0.262268150692442	no	2468	0.267126687061104	799	4361398			
SGTC_2654	protoveratrine a	100	µM	-0.621861791559505	0.262144579391724	no	2469	0.267016375489317	833	5702278	A heart drug and vasodilator.		
SGTC_1117	retinoic acid	1.10837	µM	-0.622791231195327	0.261802362212064	no	2470	0.266710860707291	813	444795	A transcription inhibitor binds retinoic acid receptor (RAR), which is bound to DNA as a heterodimer with the retinoid X receptor (RXR).		
SGTC_2542	2-hydroxy-5 (6)epoxy-tetrahydrocaryophyllene	100	µM	-0.62341477477695	0.261572903647638	no	2471	0.266505995663014	805	5024745			
SGTC_1823	3-hydroxy-2-naphthoic acid	106	µM	-0.623743027221908	0.261452151118847	no	2472	0.266398180414239	831	7104			
SGTC_1074	carmofur	3.8	µM	-0.625718542971523	0.260726033351025	no	2473	0.265749784250711	820	2577	Carmofur is a derivative of 5-fluorouracil (5-FU). 5-FU is a pyrimidine analog that inhibits thymidylate synthase and is metabolized into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition to being incorporated in DNA and RNA, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex.		
SGTC_2294	7971431	200	µM	-0.627058346851955	0.260234168152265	no	2474	0.265310494726681	836	5741572			
SGTC_2362	9071156	126	µM	-0.627369895678418	0.260119861747684	no	2475	0.265208398194507	813	653133			
SGTC_2443	5493264	126.67	µM	-0.62771983601125	0.259991500475629	no	2476	0.265093744314984	819	5340055			
SGTC_833	3852-0053	558	µM	-0.628424770930672	0.259733023200654	no	2477	0.264862857056992	821	3123681			
SGTC_636	0kpi-0074	126	µM	-0.628720417152921	0.259624658595519	no	2478	0.264766054514824	819	616434			
SGTC_2009	4012297	12.05	µM	-0.628720969519641	0.259624456155785	no	2479	0.264765873671908	811	45595307			
SGTC_3212	9128307	49.47	µM	-0.629867235119413	0.259204530970767	no	2480	0.264390725702588	784	27243542			
SGTC_2835	9006588	71.43	µM	-0.63020985468437	0.259079083232668	no	2481	0.264278646266423	776	2345538			
SGTC_3108	9121785	49.47	µM	-0.630841190069113	0.258848006480465	no	2482	0.264072184039746	800	17140271			
SGTC_617	3770-0098	35	µM	-0.6308715233529	0.258836906799711	no	2483	0.264062266378026	810	5962639			
SGTC_1289	0976-0073	69.1	µM	-0.631472121170238	0.258617184285769	no	2484	0.263865936156636	816	3391136			
SGTC_1300	1094-0077	113	µM	-0.632854544902664	0.258111806045424	no	2485	0.263414316777003	815	5532636			
SGTC_3306	9127676	59.7925	µM	-0.633052134876015	0.258039614129314	no	2486	0.263349799016505	809	41905287			
SGTC_2590	3,4',5',6',7'-pentamethoxyflavone	100	µM	-0.63344334607102	0.25789671122788	no	2487	0.263222083192936	806	521171			
SGTC_2354	9060492	162	µM	-0.63344692602847	0.257895403718969	no	2488	0.263220914616822	817	6471895			
SGTC_2177	5811945	192	µM	-0.633727661220488	0.25779288143361	no	2489	0.263129284785935	801	5343475			
SGTC_3116	9124943	49.47	µM	-0.633751578869108	0.257784147874287	no	2490	0.263121479000851	785	41905195		YPL160W	CDC60
SGTC_1886	st057356	49.9	µM	-0.635697013150711	0.257074284696699	no	2491	0.262486961785578	794	24207747			
SGTC_1955	wogonin	32.4	µM	-0.638857418236471	0.25592326581608	no	2492	0.261457845657358	785	5281703	A flavanone.		
SGTC_651	3253-0966	34.4	µM	-0.640091169238006	0.255474664872891	no	2493	0.261056664878561	808	781462			
SGTC_2272	7805186	180	µM	-0.642200465803479	0.254708661846575	no	2494	0.260371515306671	841	2956062		YPR165W	RHO1
SGTC_2225	6654152	15.4	µM	-0.643180248159605	0.254353257821341	no	2495	0.260053574107551	822	97582		YGR029W | YLR033W	ERV1 | RSC58
SGTC_1229	0139-0193	12.2	µM	-0.643670936700593	0.254175364312464	no	2496	0.25989442002512	814	3090752			
SGTC_1690	st023502	41.2	µM	-0.643958064082977	0.254071299838277	no	2497	0.259801314002902	823	24207482			
SGTC_1730	st033808	45.1	µM	-0.64500695209832	0.253691338115045	no	2498	0.259461340243177	820	1045166			
SGTC_2674	ligustilide	100	µM	-0.645429804257563	0.253538243540571	no	2499	0.259324347124313	797	5319022	A signalling  regulator.		
SGTC_2723	salbutamol	83.58	µM	-0.646528927221764	0.2531405307713	no	2500	0.258968434735231	818	9884233	β2-adrenoceptor agonist		
SGTC_2334	9017922	200	µM	-0.647186480053471	0.252902755166816	no	2501	0.258755630188135	822	3163164			
SGTC_213	1246-0773	967	nM	-0.647402203790234	0.252824773603497	no	2502	0.258685834999565	807	6251622			
SGTC_470	aa-861	153	µM	-0.64743447773138	0.252813108046554	no	2503	0.258675393937145	804	1967	aa-861 is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.		
SGTC_546	peri-Naphthalide	147	µM	-0.647504713247557	0.252787722091956	no	2504	0.258652672538781	799	223824	A penicillin ester.		
SGTC_1097	itavastatin 	7.23	µM	-0.647638892350298	0.252739228071798	no	2505	0.258609268072669	810	5282451	Itavastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YOR319W	HSH49
SGTC_2322	7413319	38.22	µM	-0.648492186619072	0.252430951426964	no	2506	0.258333331385126	809	1840400			
SGTC_475	α-linolenic acid	10	µM	-0.648549887186627	0.252410112623623	no	2507	0.258314677793485	809	5280934	Alpha-linolenic acid (ALA) is a polyunsaturated n−3 (omega-3) fatty acid. ALA has been noted to be a reactive oxygen species scavenger that temporarily improves cell proliferation.		
SGTC_1628	st004252	77.7	µM	-0.648834006726773	0.252307514879007	no	2508	0.258222837060888	800	692968			
SGTC_476	mead acid	10	µM	-0.649907983498982	0.251919892348949	no	2509	0.257875830481054	822	5312531	An omega 9 fatty acid.		
SGTC_2118	5526350	200	µM	-0.650065847509424	0.251862942160465	no	2510	0.257824844335498	818	743594			
SGTC_1644	st010134	20.9	µM	-0.650840960389439	0.251583415156207	no	2511	0.257574578096453	828	3818134			
SGTC_216	k038-0035	28.382	µM	-0.651199022740766	0.251454343395881	no	2512	0.257459010560498	819	4444231		YPR107C	YTH1
SGTC_2578	7,8-dihydroxyflavone	64.44	µM	-0.652329758323087	0.25104697376608	no	2513	0.257094233387034	809	1880	Intensifies effect of antibiotics on Staphylococcus aureus.		
SGTC_2865	9030313	51.95	µM	-0.653471596246888	0.250635958904707	no	2514	0.256726147519936	820	42562754			
SGTC_2725	haloperidol	53.21	µM	-0.654081520419033	0.250416557333008	no	2515	0.256529643241303	817	3559	Haloperidol is a D2, D3, and D4 dopamine antagonist of the typical antipsychotic class of medications. It is a butyrophenone derivative and has pharmacological effects similar to the phenothiazines.		
SGTC_2935	9038016	29.96	µM	-0.655435967931694	0.249929700510099	no	2516	0.256093550108876	812	6463195			
SGTC_1985	st071382	65.5	µM	-0.656293546766741	0.249621703308632	no	2517	0.255817634440381	828	6123237			
SGTC_3010	9080089	71.4286	µM	-0.65737905142502	0.249232136445269	no	2518	0.255468609019883	806	17027233			
SGTC_2081	5214970	32.255	µM	-0.657554116901574	0.249169339081923	no	2519	0.255412343024271	808	2063512			
SGTC_3193	9111931	49.47	µM	-0.658678023856801	0.248766385334188	no	2520	0.255051273942276	854	17087244			
SGTC_2859	9028643	45.46	µM	-0.659663446860962	0.248413367845704	no	2521	0.254734914383938	795	17151580			
SGTC_840	0245-0196	390	µM	-0.660222359426508	0.24821326199001	no	2522	0.254555572815625	817	3827528			
SGTC_1110	3-hydroxy-3'-methoxyflavone	1.24133	µM	-0.660818964238165	0.247999756174869	no	2523	0.254364209724658	822	676296	Flavone; oxidizing agent.		
SGTC_2992	9074591	71.4286	µM	-0.66084411479855	0.247990757745345	no	2524	0.254356144250652	829	17741321			
SGTC_2490	carminic acid	95.39	µM	-0.661628928735781	0.247710052640028	no	2525	0.254104531487738	802	14749	Coloring matter from the insect Coccus cacti L. It is used in foods, pharmaceuticals, toiletries, etc., as a dye, and also has use as a microscopic stain and biological marker.		
SGTC_2646	retinol	96.75	µM	-0.662299937303468	0.247470187021587	no	2526	0.253889508507684	824	445354	A vitamin A analog and teratogen.		
SGTC_2826	7992541	19.48	µM	-0.662793392567008	0.247293870662234	no	2527	0.253731442988907	874	2985066			
SGTC_2495	cafestol	54.53	µM	-0.663120934911419	0.247176873695871	no	2528	0.25362655188499	833	16667697	An anti-infammatory.		
SGTC_498	2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)	150	µM	-0.664432079495327	0.246708834060243	no	2529	0.253206903339775	827	2374	Ca(2+)-ATPase inhibitor.		
SGTC_2673	kobusone	100	µM	-0.665187186138141	0.246439498952952	no	2530	0.252965387631009	843	6710676	An epoxy ketone and protein crosslinker.		
SGTC_128	0906-2981	13.371	µM	-0.665325715324308	0.246390104800216	no	2531	0.252921093179212	834	6740226			
SGTC_1728	st035614	33.7865	µM	-0.665966455470198	0.246161710677349	no	2532	0.252716270814916	820	15945546			
SGTC_323	4013-0906	34.3	µM	-0.665972124126163	0.246159690571411	no	2533	0.252714459132426	795	2910086			
SGTC_932	2857-0803	154	µM	-0.666434637121268	0.245994897466512	no	2534	0.252566664654836	826	674898			
SGTC_1844	rapamycin	4	nM	-0.666589365116838	0.245939781189767	no	2535	0.252517232009116	823	5284616	Rapamycin is an potent immunosuppressive and anticancer drug. It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin blocks downstream elements that result in cell cycle arrest in G1. that acts by inhibiting TOR. TOR (target of rapamycin) is a phosphatidylinositol kinase-related protein kinase that controls cell growth in response to nutrients.	YHR186C | YKL203C	KOG1 | TOR2
SGTC_2141	5621638	7.665	µM	-0.667904783341441	0.245471478573248	no	2536	0.252097186931433	816	2856238			
SGTC_2469	5655019	90.81	µM	-0.668050802629781	0.245419523743145	no	2537	0.252050582155429	821	2788239			
SGTC_584	0986-0246	15.4	µM	-0.669248533515635	0.244993584635209	no	2538	0.251668475656905	853	53315		YDR232W	HEM1
SGTC_1907	st060210	83.7	µM	-0.669948940423048	0.244744689142352	no	2539	0.251445169957132	818	688793			
SGTC_3325	9138760	55.175	µM	-0.670389147763763	0.244588327450449	no	2540	0.25130487542224	809	43844959			
SGTC_1632	st005650	90	µM	-0.672382390125928	0.243881001417571	no	2541	0.250670145321695	817	2759605			
SGTC_2385	9074692	200	µM	-0.672407498595123	0.243872098420563	no	2542	0.250662155174407	816	17046906			
SGTC_3342	9147791	14.508	µM	-0.672776822842533	0.243741163164996	no	2543	0.250544642483695	816	1838168			
SGTC_2633	5,7-dihydroxyisoflavone	100	µM	-0.673699726965621	0.243414135111916	no	2544	0.250251117748081	827	5377381			
SGTC_1093	fluphenazine	7.97	µM	-0.674380476313021	0.243173065822514	no	2545	0.250034725959681	832	6602611	An atypical antipsychotic.		
SGTC_1144	3486-0183	12.5	µM	-0.675642017771163	0.242726665905658	no	2546	0.249633978693149	852	6744069			
SGTC_1107	amlodipine	47	µM	-0.6756559937572	0.242721722950147	no	2547	0.249629540926464	798	2162	Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. 		
SGTC_1358	1509-0022	2.48	µM	-0.676562848125719	0.242401107824113	no	2548	0.24934167888377	838	3258434			
SGTC_1170	0310-0127	64.8	µM	-0.677709484188734	0.241996047431361	no	2549	0.248977955910482	846	774975			
SGTC_1821	st053465	65.6	µM	-0.678394425192151	0.241754260589137	no	2550	0.248760821419047	812	675086			
SGTC_2364	9055074	200	µM	-0.678671010104269	0.241656662212224	no	2551	0.248673169280419	834	6470630			
SGTC_1995	st072814	61.1	µM	-0.678973417015332	0.241549976522972	no	2552	0.248577352755502	825	5769371			
SGTC_1599	8-chlro-1-tetrahydronorharmanone	90.6	µM	-0.67927824269171	0.241442463410144	no	2553	0.248480789761914	822	4174840			
SGTC_820	1582-0060	59.9	µM	-0.681279533572202	0.240737246882523	no	2554	0.247847315490269	831	3848840			
SGTC_1731	st035964	63	µM	-0.681965876704534	0.240495651118759	no	2555	0.247630264046006	849	6739575			
SGTC_1034	k072-0165	12.7	µM	-0.682489141408102	0.240311548409129	no	2556	0.247464853302522	840	5835461			
SGTC_1704	st028805	70.8	µM	-0.682529915311393	0.2402972059582	no	2557	0.247451966624192	835	2876101			
SGTC_688	0527-0193	473	µM	-0.684087278344064	0.239749743966363	no	2558	0.246960027292182	857	4007154			
SGTC_474	dl-dihydrosphingosine	5	µM	-0.684281704059443	0.239681445041622	no	2559	0.246898648926599	803	3058739	A sphingolipid protein kinase C inhibitor.		
SGTC_2539	epi(13)torulosol	80	µM	-0.684604154204232	0.239568196409698	no	2560	0.246796872456655	826	6708597			
SGTC_2456	5770359	74.46	µM	-0.684818251776158	0.239493018732536	no	2561	0.24672930823316	850	3118787			
SGTC_1961	st076550	68.7	µM	-0.68499671031649	0.239430365098878	no	2562	0.24667299842995	835	1579337			
SGTC_3094	9117742	49.47	µM	-0.685286398435424	0.239328679790741	no	2563	0.246581606527263	854	17149698			
SGTC_1754	st042065	16.137	µM	-0.68681599582135	0.238792157207476	no	2564	0.246099344242188	828	1126236		YIL048W	NEO1
SGTC_146	3448-8650	53.125	µM	-0.687005216780479	0.238725831700522	no	2565	0.246039720502982	844	2891488		YIL048W	NEO1
SGTC_1657	st012939	43.4	µM	-0.688098085702917	0.238342957866562	no	2566	0.245695507947499	823	24207257			
SGTC_535	2293-4129	48.2	µM	-0.689136633449309	0.237979426691905	no	2567	0.245368644292168	851	396118		YIL048W	NEO1
SGTC_585	0kpi-0023	191	µM	-0.691172066209696	0.237267830371672	no	2568	0.244728708019759	809	64601			
SGTC_2035	5154463	94.595	µM	-0.692860076005431	0.236678582238025	no	2569	0.244198683238847	841	2769623			
SGTC_1302	1159-0335	255	µM	-0.693370007380647	0.236500734544165	no	2570	0.244038689706926	825	649284			
SGTC_2146	5545642	200	µM	-0.694638162826149	0.236058761692287	no	2571	0.2436410448389	829	825326			
SGTC_1020	4335-0961	93.3	µM	-0.694852685008	0.235984042241734	no	2572	0.24357381353246	856	669075			
SGTC_677	0929-0063	136	µM	-0.696602778248491	0.235374960695136	no	2573	0.243025708349384	858	1539583			
SGTC_1058	3448-5425	97.3	µM	-0.698756833652197	0.234626481735811	no	2574	0.242352004655824	835	7279705			
SGTC_1594	piperine	70.1	µM	-0.699702613792447	0.234298263729702	no	2575	0.242056521900763	826	638024	Piperine is an alkaloid from black pepper that shows chemopreventive, cytotoxic, anti-inflammatory, and antioxidant effects. It is suggested that piperine exerts its chemopreventive effect by augmenting antioxidant defense system and modulating lipid peroxidation.		
SGTC_2361	9034121	116	µM	-0.701252559274301	0.233760929647256	no	2576	0.241572707178835	865	6496917			
SGTC_1772	st048439	82.2	µM	-0.701506009959392	0.233673128553787	no	2577	0.24149364265449	820	2927068		YDL195W	SEC31
SGTC_2897	9048598	12.99	µM	-0.702932175864833	0.233179413225981	no	2578	0.241049009071465	839	6467404			
SGTC_733	4069-0007	56.1	µM	-0.703234239132084	0.233074918219679	no	2579	0.2409548924228	837	5717425		YNL287W	SEC21
SGTC_3197	9113331	49.47	µM	-0.704712567142461	0.232563884350546	no	2580	0.240494564482064	824	16610459		YLR208W | YDL195W	SEC13 | SEC31
SGTC_20	0481-0013	4.944	µM	-0.705344927643449	0.232345478024018	no	2581	0.240297803769076	835	182045			
SGTC_1940	st075990	51.1	µM	-0.706686714980484	0.231882426140383	no	2582	0.239880593600177	844	1084979			
SGTC_3272	9137413	49.47	µM	-0.706776216417975	0.231851557418997	no	2583	0.239852778432527	850	17614870			
SGTC_2755	lomerizine	42.69	µM	-0.708304458402418	0.231324825655074	no	2584	0.239378104515588	836	3949	A calcium channel blocker.		
SGTC_1558	st069300	45.6	µM	-0.708860979707176	0.231133178062869	no	2585	0.239205375811532	830	24208000			
SGTC_1493	4348-0038	111	µM	-0.709126770573368	0.231041679721972	no	2586	0.239122905770361	861	800424			
SGTC_11	0438-0307	1.3	µM	-0.711600035020041	0.230191229999373	no	2587	0.238356242675874	845	4011476			
SGTC_2906	7926292	26.41	µM	-0.711749788968236	0.230139792314213	no	2588	0.238309865173546	861	2966319			
SGTC_562	3772-2733	112	µM	-0.711870567801064	0.230098311725037	no	2589	0.238272464614701	828	2876874		YIL048W	NEO1
SGTC_2868	9035608	32.47	µM	-0.712017324754241	0.230047914774198	no	2590	0.238227023958574	839	6462614			
SGTC_1625	st003711	30.1	µM	-0.712713299045222	0.229808998416343	no	2591	0.238011592670585	851	24207034		YER133W	GLC7
SGTC_2353	9059630	146.67	µM	-0.713214240830944	0.229637119484343	no	2592	0.23785659769649	838	4779114			
SGTC_2905	7799065	20.05	µM	-0.715379532828647	0.228895011620933	no	2593	0.237187277976612	823	1296806			
SGTC_764	1951-2361	146	µM	-0.716301041621168	0.228579592797591	no	2594	0.236902741883743	836	5438930			
SGTC_1481	3346-2004	36	µM	-0.717148105311821	0.228289870897304	no	2595	0.236641357964221	865	2770522			
SGTC_789	1309-1135	70.6	µM	-0.71768324775956	0.228106942120798	no	2596	0.236476307412103	829	3092424			
SGTC_709	3807-1509	243	µM	-0.719678755681248	0.227425541041692	no	2597	0.235861404683937	873	1886677		YPL242C	IQG1
SGTC_1254	0550-0035	264	µM	-0.720808827383374	0.227040167378833	no	2598	0.235513571765701	859	15121435			
SGTC_1394	3474-0001	65.7	µM	-0.722253519144359	0.226548039595292	no	2599	0.235069312167723	821	5017666		YIL048W	NEO1
SGTC_1151	3909-8316	15.3	µM	-0.722520110982606	0.226457292140507	no	2600	0.234987382685602	846	800431			
SGTC_101	0490-5701	117.494	µM	-0.722552531099203	0.22644625778233	no	2601	0.234977420353291	826	4661669			
SGTC_2993	9054257	71.4286	µM	-0.724000783444222	0.225953647250236	no	2602	0.234532627047529	843	6470217		YGL055W	OLE1
SGTC_158	k038-0087	26.446	µM	-0.726303814213192	0.225171540427368	no	2603	0.233826270811476	821	X158			
SGTC_1084	voriconazole	435	nM	-0.727642556908016	0.224717610557497	no	2604	0.233416211180571	861	71616	Voriconazole is an antifungal that acts by inhibiting lanosterol 14α-demethylase, thereby preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YJL195C	YJL195C
SGTC_2335	9018011	154.17	µM	-0.727896916963779	0.224631422947362	no	2605	0.233338345299274	834	6458208			
SGTC_3005	9076496	71.4286	µM	-0.730217504070325	0.22384597935517	no	2606	0.232628622372857	842	21368410			
SGTC_250	brefeldin a	552.239	µM	-0.730563526216304	0.223728995935606	no	2607	0.23252289867247	839	6436187	Brefeldin A inhibits transport of proteins from ER to Golgi and induces retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum. 		
SGTC_91	0417-1751	58.384	µM	-0.732211935749342	0.223172177863397	no	2608	0.232019610159408	848	6795624			
SGTC_860	0443-0016	25.1	µM	-0.732413811519284	0.223104040292608	no	2609	0.231958015639658	853	5337942			
SGTC_1672	st016598	6.51	µM	-0.732925598843162	0.222931353757042	no	2610	0.231801904502858	858	4665860		YNL267W	PIK1
SGTC_1889	st059080	5.18	µM	-0.733432479251837	0.222760397978356	no	2611	0.231647347835882	842	176925	Isolated from Daphnopsis sellowiana.		
SGTC_1390	3413-2614	145	µM	-0.734879887205553	0.222272641536446	no	2612	0.231206324233807	867	3421432			
SGTC_956	1185-0240	191	µM	-0.735365144154251	0.222109253156109	no	2613	0.231058571900632	851	1416193			
SGTC_2878	9043973	25.97	µM	-0.735796316718236	0.221964132788273	no	2614	0.230927331554144	867	6465167			
SGTC_395	anisomycin	6.25	µM	-0.738798863238773	0.220955063830875	no	2615	0.230014571098993	866	6610309	Antibiotic isolated from Streptomyces griseolus that inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in eukaryote ribosomes.		
SGTC_504	lovastatin	124	µM	-0.738952896110127	0.220903368748511	no	2616	0.229967800315972	860	53232	Lovastatin is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis.	YNL163C	RIA1
SGTC_1693	xanthone	101.9	µM	-0.739433299011187	0.220742184866549	no	2617	0.22982196421811	864	7020	An insecticide.		
SGTC_972	1319-0219	195	µM	-0.740483526508896	0.22039004918017	no	2618	0.22950332665092	857	23903702			
SGTC_2570	licareol	100	µM	-0.741205337287685	0.220148216684143	no	2619	0.229284473875331	851	443158			
SGTC_1826	st055655	41.6	µM	-0.741891964245666	0.219918313342855	no	2620	0.229076397458573	851	676168			
SGTC_1021	4476-0760	85.3	µM	-0.742740425292747	0.219634413491456	no	2621	0.228819424987564	865	746768			
SGTC_797	k781-0471	270	µM	-0.744565693547988	0.219024382355255	no	2622	0.228267156834564	847	23738129			
SGTC_276	colchicine	750	µM	-0.746995616219883	0.218213781006578	no	2623	0.227533103507558	857	2833	A microtubule depolymerizer.		
SGTC_1829	berberine	14.4	µM	-0.748047737113523	0.217863339510062	no	2624	0.227215682046018	834	2353	Berberine is a quaternary ammonium salt and isoquinoline alkaloid.		
SGTC_1849	st056239	19.2	µM	-0.748072613998611	0.217855057421776	no	2625	0.227208179791962	839	5393181			
SGTC_1794	st048918	76.9	µM	-0.748434056916301	0.217734745232491	no	2626	0.227099193287479	811	672303			
SGTC_1199	1638-0010	4.46	µM	-0.749501290359209	0.217379722887368	no	2627	0.226777560600868	851	3111136			
SGTC_777	1315-0167	517	µM	-0.750408620599877	0.217078156460036	no	2628	0.226504320275627	843	4221767			
SGTC_2956	9076196	2.52	µM	-0.750818048880674	0.216942155293247	no	2629	0.226381082820462	873	16423868			
SGTC_334	1502-1024	68.5	µM	-0.751043743228098	0.216867206705869	no	2630	0.226313165268431	851	3296216			
SGTC_1711	st032263	62.8	µM	-0.752300017120155	0.216450296873713	no	2631	0.225935328784193	865	3958979			
SGTC_1879	gemcitabine	100	µM	-0.752473083600391	0.216392899019646	no	2632	0.225883305338006	878	60750	A nucleoside analog which inhibits DNA replication.		
SGTC_2651	TUB2.036	5	µM	-0.753676741819074	0.215993947058274	no	2633	0.225521675463509	846	15992207		YFL037W	TUB2
SGTC_693	4161-2696	114	µM	-0.753845916042608	0.215937908513556	no	2634	0.225470874643916	871	805759			
SGTC_856	0433-0016	11.3	µM	-0.754019836204691	0.215880306671055	no	2635	0.225418655434132	851	3911780			
SGTC_3335	9143315	29.6265	µM	-0.754135952920765	0.215841854115973	no	2636	0.225383795414986	833	4899691			
SGTC_3188	9110789	49.47	µM	-0.754320592167885	0.215780718201757	no	2637	0.225328370167076	871	849217			
SGTC_1557	sumaresinolic acid	42.3	µM	-0.754468741768504	0.215731671635401	no	2638	0.225283904009859	851	9982268	A natural terpine and antifungal of unknown mechanisn.		
SGTC_1812	st052057	4.327	µM	-0.754720321321362	0.215648398244421	no	2639	0.22520840539837	863	3645418			
SGTC_3109	9122853	49.47	µM	-0.755853209097966	0.215273640872158	no	2640	0.22486860526514	895	1234709			
SGTC_1646	st011709	75.6	µM	-0.756104030959348	0.215190720552483	no	2641	0.224793412681803	854	5757843			
SGTC_1577	3(2'-chlorophenyl)-7-ethoxycoumarin	66.5	µM	-0.756183983918041	0.215164292443877	no	2642	0.224769446996407	873	689007			
SGTC_138	0850-0259	40.9225	µM	-0.758731788697078	0.214323113569201	no	2643	0.22400650842163	850	6813004			
SGTC_2166	5933061	31.504	µM	-0.759188756468969	0.214172444426929	no	2644	0.223869825475384	874	2877375			
SGTC_1321	1326-2144	215	µM	-0.759350881947256	0.214119004035138	no	2645	0.223821343759737	871	3513030			
SGTC_1874	staurosporine	7.6	µM	-0.760661619143971	0.213687239107264	no	2646	0.223429602453205	853	46864193	The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. Staurosporine is a prototypical ATP-competitive kinase inhibitor in that it binds to many kinases with high affinity, though with little selectivity.	YPR165W	RHO1
SGTC_990	3985-0011	41.3	µM	-0.762148298984621	0.213198131976167	no	2647	0.222985749513814	862	5399565		YGL099W	LSG1
SGTC_3110	9122132	49.47	µM	-0.762635198564564	0.213038087506079	no	2648	0.222840493358265	841	918317			
SGTC_1486	3970-0793	4.53	µM	-0.763809656915544	0.212652330226122	no	2649	0.222490340587166	871	2844330			
SGTC_2901	5-(ethoxymethyl)quinolin-8-ol	39.67	µM	-0.763984081846319	0.2125950742099	no	2650	0.222438364346407	875	279621			
SGTC_2276	7947513	42.08	µM	-0.764086750554393	0.212561376808487	no	2651	0.222407773715396	852	2105100			
SGTC_2320	7373003	200	µM	-0.764237363535042	0.212511949027165	no	2652	0.222362902202074	838	5415828			
SGTC_333	3486-0131	40.1	µM	-0.765519301646392	0.212091517717706	no	2653	0.221981188686588	845	6744690			
SGTC_657	3534-0529	86.7	µM	-0.768542029704822	0.21110209519238	no	2654	0.221082615351598	877	1049549			
SGTC_3098	9119039	49.47	µM	-0.76991371726948	0.210653997725285	no	2655	0.220675538198059	853	17161528			
SGTC_2188	6126565	140.678	µM	-0.770398082152786	0.21049590073883	no	2656	0.220531895360805	844	874518			
SGTC_2484	5809818	12.04	µM	-0.77140534895779	0.210167351334094	no	2657	0.220233352792486	845	2870548			
SGTC_1607	st000305	50.6	µM	-0.772432205684876	0.209832722363297	no	2658	0.219929242681323	867	5457690			
SGTC_582	0987-0078	156	µM	-0.773420919817916	0.209510819340601	no	2659	0.219636656588423	878	1625765			
SGTC_796	1234-0020	70.7	µM	-0.773497036850099	0.209486049400884	no	2660	0.219614140859592	835	46495034			
SGTC_2538	3',7'-epoxycaryophyllan-6-one	100	µM	-0.775185910084045	0.208936901046051	no	2661	0.219114906361948	859	4330530			
SGTC_153	4077-0274	519.67	µM	-0.778467602338203	0.207872264981861	no	2662	0.218146699384836	857	3121976			
SGTC_1392	3455-1037	33.9	µM	-0.780027404119173	0.207367364319887	no	2663	0.217687372501821	839	981132			
SGTC_600	1495-0418	41.6	µM	-0.780962954033651	0.20706487927712	no	2664	0.217412141819596	876	5377768			
SGTC_3312	9133330	71.43	µM	-0.781608332813592	0.206856365546578	no	2665	0.217222394131572	884	17617324			
SGTC_2231	micatex	6.853	µM	-0.782589422191781	0.206539626149473	no	2666	0.216934127548172	876	20737	An antifungal of unknown mechanism.		
SGTC_1161	k007-0610	110	µM	-0.783071675781101	0.206384038559443	no	2667	0.216792511469685	867	5843850			
SGTC_2630	antimycin a	100	µM	-0.784111463520055	0.20604881230192	no	2668	0.216487354759195	887	5702199	Antimycin a is an antibiotic that inhibits complex III of the mitochondrial electron transport chain.		
SGTC_2355	9061122	103.12	µM	-0.784174388332998	0.206028535788546	no	2669	0.216468895576183	881	5302957			
SGTC_1880	MG-132	525	µM	-0.78546022185803	0.205614455731716	no	2670	0.216091891958339	854	462382	MG-132 [Z-Leu-Leu-Leu-CHO] is a proteasome inhibitor, often used as a tool for perturbing the proteasome-regulated degradation of intracellular proteins.	YDR086C	SSS1
SGTC_1939	st074455	53.6	µM	-0.786293038130585	0.205346525709967	no	2671	0.215847915076648	870	1644229			
SGTC_1751	st044839	27.194	µM	-0.786830535373893	0.205173714602614	no	2672	0.215690537892439	846	5291326			
SGTC_587	k089-0003	57	µM	-0.787074214347684	0.205095397686758	no	2673	0.2156192115211	853	9659696			
SGTC_2479	5617353	43.85	µM	-0.788813430813861	0.204536940395484	no	2674	0.215110529214698	868	2731746			
SGTC_3283	9109332	35.8195	µM	-0.790725316639598	0.203924084774362	no	2675	0.214552149649834	845	17027281			
SGTC_71	0417-1750	47.813	µM	-0.792269002835458	0.203430055051213	no	2676	0.214101920794149	838	6811472			
SGTC_1066	ketoconazole	628	nM	-0.792510328975726	0.20335288743606	no	2677	0.214031585756792	868	456201	Ketoconazole is an imidazole antifungal; acts by inhibiting lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YBR102C | YOR262W | YPR112C | YDR280W | YMR079W | YDL163W	EXO84 | GPN2 | MRD1 | RRP45 | SEC14 | YDL163W
SGTC_2411	st077133	39.94	µM	-0.794477826088682	0.202724402981365	no	2678	0.213458656358805	884	1403142		YNL221C	POP1
SGTC_3055	9094636	49.47	µM	-0.796056958474617	0.202220815851396	no	2679	0.212999464935038	877	25236176			
SGTC_2832	7992762	51.95	µM	-0.796558313948878	0.202061089663247	no	2680	0.212853797829952	866	2985177			
SGTC_3242	9133940	49.47	µM	-0.796662326816036	0.20202796179838	no	2681	0.212823584534341	873	17248444			
SGTC_1842	st055362	61.2	µM	-0.797796698966601	0.201666877899043	no	2682	0.212494238621678	857	676032			
SGTC_2401	5128683	200	µM	-0.798983784677649	0.201289428881406	no	2683	0.212149907224846	887	708373			
SGTC_3088	9117578	49.47	µM	-0.800504317221896	0.200806575354125	no	2684	0.211709331618109	894	678341			
SGTC_1565	sinapyl alcohol	95.1	µM	-0.80216788210459	0.200279098188538	no	2685	0.211227926213743	871	5280507	A phenol propionate derived from cinnamic acid.		
SGTC_691	1548-0686	185	µM	-0.80326687108693	0.199931091829144	no	2686	0.210910250916034	860	46495133			
SGTC_408	cantharidin	100	µM	-0.803276028361088	0.199928193610884	no	2687	0.210907605078907	864	2545	Cantharidin is a toxic blistering agent secreted by the Spanish fly of unknown mechanism. In Saccharomyces cerevisiae, cantharidin is thought to act by inhibiting GLC7 (encoding  type 1 serine/threonine protein phosphatase) as decreased expression confers hypersensitivity and overexpression confers resisitance (Hoon et al., Nat Chem Biol 4, 2008).	YER133W	GLC7
SGTC_1235	benzylparaben	21.5	µM	-0.803594212862447	0.199827505957158	no	2688	0.210815683218177	880	7180			
SGTC_3311	9131146	2.8755	µM	-0.804798525030896	0.199446684577898	no	2689	0.210467976481458	868	4900406		YPR165W	RHO1
SGTC_2106	5357045	167.29	µM	-0.805745544531549	0.199147530036306	no	2690	0.210194791374286	866	668842			
SGTC_455	paf C-16	10	µM	-0.805984771908155	0.199072003147002	no	2691	0.210125814823334	868	108156	Platelet-activating factor, also known as a PAF; natural lipid; potentphospholipid activator and mediator of lipid signaling processes, including platelet aggregation and degranulation, inflammation and andanaphylaxis.		
SGTC_245	methotrexate	289.6	µM	-0.807371428328887	0.198634559477031	no	2692	0.209726261458289	846	126941	Methotrexate is an antineoplastic antimetabolite with immunosuppresent properties. Potent inhibitor of dihydrofolate reductase (DHFR), a key enzyme in folic acid biosynthesis.Methotrexate inhibits folate-dependent processes including DNA, RNA and methionine biosyntheis.	YOR074C | YOR236W | YFR051C	CDC21 | DFR1 | RET2
SGTC_197	4544-0043	41.561	µM	-0.807580078801391	0.198568787453217	no	2693	0.209666179272297	877	896523			
SGTC_1105	epirubicin	18.1	µM	-0.808816597944616	0.198179274318826	no	2694	0.209310323777039	867	65348	Epirubicin forms complexes with DNA by intercalation between base pairs, thereby preventing DNA replication. Additionally,epirubicin inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the topoisomerase II reaction.		
SGTC_2525	harmine	47.85	µM	-0.809161491395035	0.198070712530089	no	2695	0.209211130984296	837	5280953	A monoamine oxidase inhibitor		
SGTC_126	0417-1624	672.48	µM	-0.811032939056115	0.197482265044593	no	2696	0.208673377510374	891	41912		YDL195W	SEC31
SGTC_1579	chlormadinone acetate	49.4	µM	-0.812860718319222	0.196908569930889	no	2697	0.208148959243805	886	45114258	A steroidal progestin.		
SGTC_382	3229-0966	23.2	µM	-0.81301668288727	0.19685966324154	no	2698	0.208104246629791	884	5722370			
SGTC_1411	3909-8223	150	µM	-0.813386480986741	0.196743732962168	no	2699	0.207998253928284	877	X1411			
SGTC_1076	itraconazole	331	nM	-0.815039905940724	0.196225896532476	no	2700	0.207524733994082	868	3793	Itraconazole is a triazole antifungal; inhibits lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YOR217W	RFC1
SGTC_132	0417-1715	25.805	µM	-0.815708937914916	0.196016597365941	no	2701	0.207333312917762	879	6769098			
SGTC_3301	9125354	19.7965	µM	-0.816758334487882	0.195688578313695	no	2702	0.207033273648813	850	41905162			
SGTC_435	c-PAF	6.7	µM	-0.821527418024464	0.194202067035102	no	2703	0.205672956616073	866	124663	C-PAF (Carbamyl-Platelet-Activating-Factor) is a non-hydrolyzable bioactive analog of PAF used a chemical tool to determine the biological processes of PAF including stimulating human neutrophils and cause cultured retinal endothelial cell death in rats. Stimulates neutrophil degranulation responses, but resists metabolic inactivation by acetylhydrolase		
SGTC_1965	Pectolinarigenin	58.4	µM	-0.821612442224029	0.194175627759136	no	2704	0.205648752836337	889	5320438	An anti-inflammatory.		
SGTC_852	0418-0143	439	µM	-0.821700006725204	0.194148400838252	no	2705	0.20562382767798	864	5369229			
SGTC_505	gw-5074	63.9	µM	-0.823289826070004	0.193654473883684	no	2706	0.205171598917928	891	5924208	A c-Raf1 kinase inhibitor, which inhibits other kinases.		
SGTC_254	nsc-64875	3.808	µM	-0.824871412010439	0.193163865951903	no	2707	0.204722299112792	873	56993			
SGTC_1917	st066507	28.5	µM	-0.825526048791855	0.192961019847408	no	2708	0.204536500095295	875	3156428			
SGTC_515	4092-1064	102	µM	-0.826083949706585	0.192788251086903	no	2709	0.204378235879423	904	717353			
SGTC_2941	9056145	11.23	µM	-0.826248819090609	0.192737213021951	no	2710	0.20433148002073	867	2119517			
SGTC_1120	ficusin	1.78878	µM	-0.826494734195728	0.192661101246123	no	2711	0.204261751970118	898	6199	A DNA cross-linker.		
SGTC_1430	4049-0248	69.1	µM	-0.827807723381529	0.192255036409186	no	2712	0.203889700016612	875	22774488			
SGTC_1065	prochlorperazine maleate	2.48	µM	-0.828675585068318	0.19198692260991	no	2713	0.203644002372013	887	6436057	A phenothiazine class of antipsychotic, more potent than chlorpromazine.		
SGTC_18	0111-0177	500	nM	-0.828682666526301	0.191984735833598	no	2714	0.203641998288739	890	721752			
SGTC_1753	st043925	64	µM	-0.830185059187098	0.1915211370459	no	2715	0.203217080634901	897	670181			
SGTC_767	0929-0023	86	µM	-0.831125067038886	0.191231424496672	no	2716	0.202951490103628	881	1204563			
SGTC_3198	9112019	49.47	µM	-0.831337922261338	0.191165859358999	no	2717	0.202891378626219	922	45595555			
SGTC_239	5hr heat shock (37°C) + mitomycin C	819.444	µM	-0.832017466094375	0.190956633821885	no	2718	0.202699542920436	856	5746	Mitomycin is a bifunctional and trifunctional alkylating agent, cross-links DNA inhibiting DNA synthesis and function. Mitomycin is cell cycle phase-nonspecific.		
SGTC_1363	1636-0063	10.4	µM	-0.832529571172532	0.190799054045847	no	2719	0.202555046939542	865	6072185			
SGTC_2627	acetyl isogambogic acid	100	µM	-0.833248958004074	0.190577826450989	no	2720	0.202352168207188	899	6857789	A caspase activator and apoptosis inducer.		
SGTC_1513	0337-0559	19	µM	-0.836184026841738	0.189676859878566	no	2721	0.201525691501456	880	775073			
SGTC_1904	st060225	78	µM	-0.836210300843791	0.189668806500909	no	2722	0.201518302234371	865	66595			
SGTC_698	k064-0052	127	µM	-0.839830690868726	0.188561114363268	no	2723	0.200501661402666	922	5088751			
SGTC_1768	st044301	37.178	µM	-0.840312129850131	0.188414114676795	no	2724	0.200366701060459	919	3931349			
SGTC_838	0109-0203	71.4	µM	-0.841071036084391	0.188182538379057	no	2725	0.200154070006631	863	759422			
SGTC_2598	perillyl alcohol	100	µM	-0.841801197881394	0.187959899162232	no	2726	0.199949620662234	904	10819	An apoptosis inducer.		
SGTC_92	0063-0024	660.874	µM	-0.841802914146924	0.187959376034234	no	2727	0.199949140246365	893	3594437			
SGTC_1925	st057770	10.1	µM	-0.841889611355453	0.187932951376146	no	2728	0.199924872926395	895	5989122			
SGTC_1591	genipin	88.4	µM	-0.842585263499867	0.187721004876387	no	2729	0.199730217830534	906	442424	A DNA cross-linking agent.		
SGTC_1314	1222-0010	41.1	µM	-0.844119752170311	0.187254009762077	no	2730	0.199301245592753	896	3526027			
SGTC_2715	st079500	56.4	µM	-0.846661198507907	0.186482146207254	no	2731	0.198591996010765	876	28246688			
SGTC_2038	4100038	30.985	µM	-0.851272989007731	0.185086538819755	no	2732	0.197308862896581	858	3596803			
SGTC_3221	9128209	49.47	µM	-0.851384342057347	0.185052921884256	no	2733	0.197277943398237	900	16460723			
SGTC_94	0334-0113	514.748	µM	-0.851495257892299	0.185019440712846	no	2734	0.19724714821559	888	6795178			
SGTC_3355	9151058	44.0485	µM	-0.851996034945039	0.184868322481557	no	2735	0.197108146380051	881	17015728			
SGTC_444	curcumin	90.4	µM	-0.852428097346637	0.184738001759609	no	2736	0.196988265475513	875	6610332	A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties.		
SGTC_2712	st079126	47.7	µM	-0.854260573588246	0.184185916546169	no	2737	0.196480313645644	882	3152970			
SGTC_1497	4476-2978	41.3	µM	-0.855656995544771	0.183765895177353	no	2738	0.196093766948202	871	1528379			
SGTC_1944	st076371	56.9	µM	-0.85606590716603	0.183643014140409	no	2739	0.195980662569157	877	24208455			
SGTC_1134	3477-0009	42.5	µM	-0.856288447047683	0.183576160741271	no	2740	0.195919124984802	859	3973534			
SGTC_2824	7998404	51.95	µM	-0.85696452054919	0.18337315395917	no	2741	0.195732246461917	901	837851			
SGTC_1623	st003709	20.3	µM	-0.858245419730438	0.182988918184041	no	2742	0.195378480382557	884	16192618			
SGTC_909	3448-9333	149	µM	-0.862681672155072	0.181662047095325	no	2743	0.194156255993289	904	3344074			
SGTC_2772	vinpocetine	57.06	µM	-0.865085100111356	0.180945709115335	no	2744	0.193496041042048	905	443955	Ca2+-calmodulin-dependent phosphodiesterase I (PDE1) inhibitor.		
SGTC_2950	9072895	21.46	µM	-0.86547903791542	0.1808284656368	no	2745	0.193387958201541	861	17332245			
SGTC_2496	diffractaic acid	79.83	µM	-0.866813493342796	0.180431659971295	no	2746	0.193022103838299	898	94870	An apoptosis inducer which activates caspases.		
SGTC_2047	4141938	200	µM	-0.86686447430243	0.180416511419861	no	2747	0.193008135282666	897	3807862			
SGTC_2180	6301957	200	µM	-0.866954061665761	0.180389893242421	no	2748	0.192983590240067	889	845462			
SGTC_181	1447-1644	8.07	µM	-0.867701094435723	0.180168030975752	no	2749	0.192778993289276	918	534600			
SGTC_3273	9137859	49.47	µM	-0.868169125597063	0.180029117081129	no	2750	0.192650876704914	936	2377234			
SGTC_2286	7945697	125	µM	-0.868326965096983	0.179982284728067	no	2751	0.19260768221988	897	1245733			
SGTC_299	1273-0059	1.44	µM	-0.868396551141625	0.179961640373129	no	2752	0.192588641126855	871	2848077			
SGTC_2409	alverine citrate	63.97	µM	-0.868692703361769	0.179873796406455	no	2753	0.192507616741712	878	21718	An antispasmotic used to treat irritable bowel syndrome.		
SGTC_2652	actinonin	100	µM	-0.86887942527096	0.179818425243602	no	2754	0.192456542144879	892	443600	A inhibitor of aminopeptidase M, N and leucine. Also an alanyl aminopeptidase and peptide deformylase.		
SGTC_403	arphamenine a	50	µM	-0.868973645030192	0.179790489054191	no	2755	0.19243077308036	898	5487158	An arginine aminopeptidase inhibitor.		
SGTC_2948	9070189	9.45	µM	-0.86917850130382	0.179729758511	no	2756	0.192374752256017	842	6473636		YDL196W	YDL196W
SGTC_1597	7-benzyloxygramine	47.5	µM	-0.871030135216868	0.179181418353657	no	2757	0.191868849537812	883	260807			
SGTC_1734	st037168	69.4	µM	-0.872735262293723	0.178677396238603	no	2758	0.191403696420295	918	708907			
SGTC_2894	9048625	32.47	µM	-0.873355354967906	0.178494323305052	no	2759	0.191234708649713	887	4092861			
SGTC_2615	purpurogallin-4-carboxylic acid	100	µM	-0.873860372471147	0.178345311897098	no	2760	0.191097148784866	875	269315	Purpurogallin is a red, crystalline compound, and the aglycon of several glycosides from nutgalls and oak barks. It can inhibit hydroxyestradiol methylation by catechol-O-methyltransferase.		
SGTC_1993	st073995	70.8	µM	-0.874402083372773	0.178185560825767	no	2761	0.1909496616089	892	3098394			
SGTC_1898	st060199	18.6	µM	-0.875263566137082	0.177931694556188	no	2762	0.190715256635966	871	688866			
SGTC_2838	9002687	71.43	µM	-0.877713491136444	0.177210985245718	no	2763	0.190049610615141	903	6457060			
SGTC_2210	7115885	190.385	µM	-0.877902203843715	0.177155547066343	no	2764	0.189998396563058	904	2927039			
SGTC_2765	myclobutanil	7.74	µM	-0.881030178353553	0.176238237331233	no	2765	0.189150743069328	909	6336	Myclobutanil is a general use pesticide, and more specifically, a triazole fungicide registered for use on a wide range of food crops. Like other azoles, it acts by inhibiting fungal cytochrome P450 enzyme 14α-demethylase.	YHR007C	ERG11
SGTC_635	k038-0028	24.7	µM	-0.881184657042666	0.176193012942282	no	2766	0.189108941140692	908	4035102			
SGTC_906	1165-0455	526	µM	-0.881413901899924	0.17612591393228	no	2767	0.189046917976312	895	3252859			
SGTC_2543	pimpinellin	60.67	µM	-0.883186390198929	0.175607660172999	no	2768	0.188567786844809	884	4825	From Heracleum laciniatum; cause of phototoxicity in patient with vitiligo.		
SGTC_477	mead ethanolamide	10	µM	-0.883410769014066	0.17554212354615	no	2769	0.188507187199598	871	16061185			
SGTC_212	3807-4682	38.772	µM	-0.885663266459384	0.174885072550658	no	2770	0.187899504172964	897	3125501		YBL034C	STU1
SGTC_357	1325-0123	420	µM	-0.885820067756524	0.174839391966126	no	2771	0.187857247102139	926	1098503			
SGTC_1833	st055984	71	µM	-0.88763103596048	0.174312355410703	no	2772	0.187369626701319	894	676288			
SGTC_738	1315-0003	72.4	µM	-0.888688366670153	0.174005113231959	no	2773	0.187085292462864	919	6251474			
SGTC_3114	9122766	49.47	µM	-0.894010411001653	0.172463850905478	no	2774	0.185658160428336	866	17176985			
SGTC_378	3970-0959	8.33	µM	-0.899379025351726	0.170917952018842	no	2775	0.184225403711457	909	6615653			
SGTC_1345	1488-0192	31.4	µM	-0.899394581921484	0.17091348540746	no	2776	0.18422126205343	900	658348			
SGTC_874	0599-0792	117	µM	-0.900390770177641	0.170627614778372	no	2777	0.183956165451099	889	765305			
SGTC_29	0299-0004	12.984	µM	-0.901443158326604	0.170325949472507	no	2778	0.183676371607813	892	16871	A napthoquinone isolated from Swertia calycina.		
SGTC_416	estradiol valerate	100	µM	-0.903284943634441	0.169798827494028	no	2779	0.183187342674292	906	13791	A steroid.		
SGTC_2472	5377652	49.4	µM	-0.905194744474044	0.169253345364536	no	2780	0.182681112814532	935	1610903			
SGTC_1970	st070122	35.8	µM	-0.905235330715757	0.169241765240986	no	2781	0.182670364129013	901	102928			
SGTC_1431	4049-0260	9.09	µM	-0.905635178311112	0.169127707353583	no	2782	0.182564491323201	909	3854841			
SGTC_1484	3473-2379	286	µM	-0.905742619298353	0.169097067861772	no	2783	0.182536049320613	945	671917			
SGTC_2	0422-0095	29	µM	-0.906658517662157	0.16883602119908	no	2784	0.182293703158178	876	6790840			
SGTC_2423	st077119	87.2	µM	-0.907336282422671	0.16864301346764	no	2785	0.182114496511911	886	107936	An active alkaloid of Chinese medicines from Dictamni radicis cortex (Rutaceae).		
SGTC_2033	5192550	145	µM	-0.908030996068886	0.168445326430026	no	2786	0.181930922777423	866	182073			
SGTC_1114	scopoletin	1.73284	µM	-0.909972795882751	0.167893560458803	no	2787	0.181418428381003	909	5280460	A coumarin with genotoxic properties.		
SGTC_2380	9035439	200	µM	-0.910268005814907	0.16780977801821	no	2788	0.181340593581013	913	6462575			
SGTC_1173	0443-0020	122	µM	-0.910291631020603	0.167803074199369	no	2789	0.181334365483114	917	5331295			
SGTC_1167	k781-0610	148	µM	-0.914312593021532	0.166664610289167	no	2790	0.180276307686912	888	4525169			
SGTC_2371	9071574	200	µM	-0.915836534406983	0.166234438996176	no	2791	0.179876319106794	923	45596039			
SGTC_684	1140-0066	328	µM	-0.916546716725332	0.166034217126237	no	2792	0.179690108255733	895	6813534			
SGTC_772	k072-0172	35.3	µM	-0.917773361478122	0.165688756049215	no	2793	0.179368765584319	877	5861980			
SGTC_1791	st048313	56.1	µM	-0.918860099185069	0.165383085681519	no	2794	0.179084376246105	862	1204976			
SGTC_954	1189-0853	2.85	µM	-0.920431287811745	0.16494179767209	no	2795	0.178673712374562	897	2828194			
SGTC_412	gemfibrozil	100	µM	-0.920916155005368	0.164805770748465	no	2796	0.178547101748476	891	3463	A peroxisome proliferator-activated receptor activator which lowers lipid levels.		
SGTC_494	Boc-Gly-Val-Val-CHO	140	µM	-0.92348007742838	0.164087684319595	no	2797	0.177878538968123	916	6610324	An aldehyde inhibitor of gamma-secretase. The exact mechanism of DNA strand scission is unresolved, but it has been suggested that bleomycin chelates metal ions (primarily iron), producing a pseudoenzyme that reacts with oxygen to produce superoxide and hydroxide free radicals that cleave DNA.		
SGTC_3184	9108758	49.47	µM	-0.92541664931004	0.163546649556781	no	2798	0.177374610830692	924	902885			
SGTC_1564	D-Arginine	115	µM	-0.925965405610525	0.163393550226336	no	2799	0.177231979389102	927	71070	D-isomer of arginine; arginine decarboxylase inhibitor.		
SGTC_3124	9127567	49.47	µM	-0.926602523360735	0.163215915470439	no	2800	0.177066472145368	920	17592030			
SGTC_1921	5740136	50	µM	-0.929347649394306	0.162451982810204	no	2801	0.176354474353937	902	1774243			
SGTC_2566	crystal violet carbinol	226	nM	-0.930450098305261	0.162145841664512	no	2802	0.176069044937931	927	68050	Cationic dye that binds acidic phospholipids including cardiolipin.		
SGTC_1461	k072-0203	53.8	µM	-0.932439285965608	0.161594411442027	no	2803	0.175554774916413	901	5418714			
SGTC_3074	9116018	49.47	µM	-0.933149129607567	0.161397929318249	no	2804	0.17537148783579	957	17027303			
SGTC_2154	5570129	200	µM	-0.934358458345887	0.161063550512557	no	2805	0.175059509387934	938	673366			
SGTC_2222	6885208	172.143	µM	-0.942822039529015	0.158736037393543	no	2806	0.172885968299547	920	609514			
SGTC_1773	st048542	73.5835	µM	-0.943729659824355	0.158487754430059	no	2807	0.172653906685796	907	3237138			
SGTC_630	4356-0227	183	µM	-0.943921764808528	0.158435236064473	no	2808	0.17260481449407	912	779312			
SGTC_2797	7859098	81.82	µM	-0.945823261080249	0.15791601383108	no	2809	0.172119369596788	893	972681			
SGTC_2357	9067248	200	µM	-0.946253958353392	0.157798563085758	no	2810	0.172009535347881	953	9150235			
SGTC_1593	justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one	54.9	µM	-0.946379230130938	0.157764412361934	no	2811	0.171977597571685	941	442882			
SGTC_2015	5119600	184	µM	-0.947135385763789	0.157558377549127	no	2812	0.171784897685883	927	2828786			
SGTC_3280	9140961	49.47	µM	-0.947835098989372	0.157367879551789	no	2813	0.171606704567696	939	4901226			
SGTC_695	3505-6186	243	µM	-0.948655317669961	0.157144766596417	no	2814	0.171397973228897	912	1819379			
SGTC_3232	9132874	49.47	µM	-0.950182968959027	0.156729775139395	no	2815	0.17100964542743	903	3784940			
SGTC_1082	camptothecin	424.86	nM	-0.950223618180975	0.156718742506283	no	2816	0.170999320118977	903	2538	Camptothecin is a Topo I (topoisomerase I) inhibitor and antineoplastic.		
SGTC_2517	totarol	10	µM	-0.950631748640525	0.156607999869644	no	2817	0.170895673009358	907	460178	An antibacterial membrane disruptor.	YGL001C	ERG26
SGTC_480	am 92016	50	µM	-0.951244481546521	0.15644183689661	no	2818	0.170740141407126	936	2129	K+ channel blocker.		
SGTC_2332	7982454	138.89	µM	-0.953070762364402	0.155947268867075	no	2819	0.170277109380734	931	2981748			
SGTC_658	3253-0951	102	µM	-0.953574720913661	0.155810975438214	no	2820	0.170149478371289	928	1184878			
SGTC_878	0828-0289	13.7	µM	-0.954836000029385	0.155470212258626	no	2821	0.16983031944441	910	745350		YLR208W	SEC13
SGTC_2813	7971799	71.43	µM	-0.954992690922014	0.155427913020416	no	2822	0.169790696601584	936	2234054			
SGTC_2952	9073731	13.78	µM	-0.957745480037299	0.154686026901672	no	2823	0.169095558574174	944	16457353			
SGTC_1060	3448-7350	82	µM	-0.960757810555302	0.153876879069473	no	2824	0.168336978096884	933	570178			
SGTC_3156	9099931	49.47	µM	-0.963534402304259	0.15313353882484	no	2825	0.167639704169412	929	18111053			
SGTC_931	2812-0076	566	µM	-0.96536012590664	0.152646061035349	no	2826	0.167182232994825	927	3450959			
SGTC_1006	4099-6547	255	µM	-0.966867681170098	0.152244312688149	no	2827	0.166805092414473	935	3146833			
SGTC_467	ro 31-8220	72.8	µM	-0.968245683754147	0.151877703466748	no	2828	0.166460842178993	922	5083	Ro-318220 is a protein kinase C (PKC) inhibitor of the bisindolylmaleimide class.	YBR109C | YER133W	CMD1 | GLC7
SGTC_2453	5731132	22.18	µM	-0.968588281890432	0.151786648424543	no	2829	0.166375326145368	946	1362040			
SGTC_1700	st030840	7.9285	µM	-0.971002300751095	0.15114608382045	no	2830	0.165773566434963	924	5499307			
SGTC_345	1362-0200	395	µM	-0.971797551245746	0.150935456962952	no	2831	0.165575637171855	956	1419823			
SGTC_2173	5763948	167	µM	-0.972464181611044	0.150759046506775	no	2832	0.165409837879872	921	2867177			
SGTC_2705	st078069	42.8	µM	-0.97282591587835	0.150663378213459	no	2833	0.165319915024059	928	1530061			
SGTC_2250	alverine citrate	130	µM	-0.974234392287769	0.150291262012684	no	2834	0.164970085899237	891	21718	An antispasmotic used to treat irritable bowel syndrome.	YIL048W	NEO1
SGTC_1865	st057639	52.2	µM	-0.974964116061289	0.150098711747541	no	2835	0.164789030024713	932	688818			
SGTC_646	4092-0839	27.3	µM	-0.976393007912844	0.149722150362008	no	2836	0.164434872560496	916	877796			
SGTC_3028	9087778	49.47	µM	-0.977998285979667	0.149299857601823	no	2837	0.164037585908025	909	17217395			
SGTC_1901	st060216	58.6	µM	-0.978305478650833	0.149219136648097	no	2838	0.163961630528352	918	688792			
SGTC_3317	9138495	8.753	µM	-0.978855082834633	0.149074789998879	no	2839	0.16382579427557	917	17020139			
SGTC_3220	9131269	49.47	µM	-0.979740190069637	0.148842523791185	no	2840	0.16360719104759	933	17722206			
SGTC_268	camptothecin	39.6153	µM	-0.980368290925664	0.148677846915197	no	2841	0.16345217803566	945	24360	Camptothecin is a Topo I (topoisomerase I) inhibitor and antineoplastic.		
SGTC_215	1287-0124	461.5	µM	-0.981244031977763	0.148448446541925	no	2842	0.163236207595541	936	5560863			
SGTC_2721	ifenprodil	61.44	µM	-0.981252828075268	0.148446143605489	no	2843	0.163234039291348	930	3689	Ifenprodil is a selective antagonist of the NMDA glutamate receptor.		
SGTC_2798	7813637	45.45	µM	-0.981841697066868	0.14829202413662	no	2844	0.163088921221525	909	956368			
SGTC_1684	st024538	14.6195	µM	-0.982200640001527	0.148198133705951	no	2845	0.163000506180868	937	6732859			
SGTC_2475	5812728	15.03	µM	-0.983116499125333	0.147958748278004	no	2846	0.16277505241888	922	776160		YPL266W | YMR113W | YBL105C | YBR192W	DIM1 | FOL3 | PKC1 | RIM2
SGTC_406	estrone	100	µM	-0.983450941380363	0.147871396982693	no	2847	0.162692774541795	910	5870	A steroid.		
SGTC_1517	deoxycholic acid methyl ester	49.2	µM	-0.983718534602472	0.14780153051993	no	2848	0.162626962028113	942	229346	A bile salt which induces apoptosis.		
SGTC_1986	st071812	45	µM	-0.984126870452103	0.147694959881367	no	2849	0.162526568321621	935	11838594			
SGTC_2282	7944268	200	µM	-0.986308296927202	0.1471265063513	no	2850	0.161990924780005	939	2970414			
SGTC_3201	9113999	49.47	µM	-0.989039936744398	0.146416744909664	no	2851	0.161321801209641	940	16649224			
SGTC_1638	st008370	60.6	µM	-0.989554433786317	0.146283320924735	no	2852	0.161195975610796	899	24207134			
SGTC_2549	cedrol	20.94	µM	-0.989651327953653	0.146258202599612	no	2853	0.161172286301535	913	6708665	A sedative which affects the nervous system.		
SGTC_1615	st002656	86.5	µM	-0.990372918714865	0.146071232382606	no	2854	0.160995938598836	943	1584458			
SGTC_2268	7933382	153.85	µM	-0.990902769974619	0.145934045759852	no	2855	0.160866529832935	924	935025		YOR257W	CDC31
SGTC_850	0388-0143	75.9	µM	-0.992120511895086	0.145619081923909	no	2856	0.160569370836658	929	67273			
SGTC_373	0844-0104	25.9	µM	-0.992763887140935	0.145452860283242	no	2857	0.160412516301698	918	5375804			
SGTC_2720	fluspirilene	36.88	µM	-0.994657246836221	0.144964434801604	no	2858	0.159951497297517	938	3396	An atypical antipsychotic.		
SGTC_964	1287-0107	19.4	µM	-0.994850404254376	0.144914668582633	no	2859	0.159904513661341	933	51516812		YPR165W	RHO1
SGTC_3130	9127414	49.47	µM	-0.995699150395406	0.144696128937309	no	2860	0.15969817152285	937	1494646			
SGTC_3145	9085516	49.47	µM	-0.996734582921668	0.144429821028187	no	2861	0.159446679326175	940	25236195			
SGTC_1537	2',6'-dihydroxyflavanone	78	µM	-0.997505424054594	0.144231779265044	no	2862	0.159259621160471	949	5106787	A p450 inhibitor.		
SGTC_1054	3429-0080	167	µM	-0.997820018726933	0.144151007346625	no	2863	0.159183320540041	941	1162877			
SGTC_184	1494-0393	24.714	µM	-0.998182102835496	0.144058080313408	no	2864	0.159095531651621	933	3090647			
SGTC_66	0109-0187	42.4	µM	-0.998371239641482	0.144009555386041	no	2865	0.159049687212599	923	759417			
SGTC_1914	st062367	72.6	µM	-0.998820926262879	0.143894228080208	no	2866	0.158940723453501	930	978205			
SGTC_115	0527-0192	112.043	µM	-1.00390237225066	0.142595362604071	no	2867	0.15771283651265	944	4233931			
SGTC_2192	5915882	198.485	µM	-1.00489947312664	0.142341427623871	no	2868	0.157472629091523	917	2876149			
SGTC_2455	5377712	9.75	µM	-1.00552593672009	0.142182040651827	no	2869	0.157321833407063	896	2243908			
SGTC_1001	4048-4355	44.4	µM	-1.00595469943611	0.142073023047979	no	2870	0.157218680922145	922	21824233			
SGTC_1297	1068-0111	14.1	µM	-1.0063967475266	0.141960686743904	no	2871	0.157112378789059	920	767057			
SGTC_532	1548-0774	215	µM	-1.00744481058071	0.141694586108095	no	2872	0.15686053329794	959	5932993			
SGTC_249	wiskostatin	11.211	µM	-1.00870038827273	0.141376243114672	no	2873	0.156559172761625	897	2775510	A n-wasp and actin depolymerizer.		
SGTC_1928	4'-methoxychalcone	40.3	µM	-1.01193371483288	0.140558688494454	no	2874	0.155784873854063	928	641818			
SGTC_2333	9017922	200	µM	-1.01841484982349	0.138929597372613	no	2875	0.154240424013843	921	3163164			
SGTC_989	1501-0895	10.3	µM	-1.01881471352605	0.138829510835237	no	2876	0.154145469575919	920	2830112			
SGTC_1910	st062352	60.4	µM	-1.01919096798757	0.138735378579392	no	2877	0.154056156871352	939	2245730			
SGTC_2787	5284540	71.43	µM	-1.02103878642476	0.13827371795865	no	2878	0.153618031418971	949	736958			
SGTC_2002	4023503	131	µM	-1.02111560434171	0.138254548401376	no	2879	0.153599835450554	955	4736863		YCR052W	RSC6
SGTC_1589	2',5'-dimethoxyflavone	47.2	µM	-1.02204421371684	0.138022961535469	no	2880	0.153379987343677	914	688667			
SGTC_3224	9130643	49.47	µM	-1.02216997702508	0.137991617646447	no	2881	0.153350228937759	947	17644395			
SGTC_1627	st003713	25.6	µM	-1.02230120876697	0.137958916040599	no	2882	0.153319180656728	941	16195070		YER133W	GLC7
SGTC_1396	3511-0007	98.6	µM	-1.02312829561391	0.13775293611854	no	2883	0.153123594997151	915	X1396			
SGTC_3059	1327-0034	3	µM	-1.02732899020698	0.136710024263999	no	2884	0.152132787970842	930	15998580		YGL093W | YPR107C	SPC105 | YTH1
SGTC_445	e6 berbamine	66	µM	-1.02838349696416	0.136449070395983	no	2885	0.151884734173225	928	6610268	A calcium/calmodulin antagonist.		
SGTC_2762	leflunomide	42.06	µM	-1.02852142222489	0.136414963888872	no	2886	0.151852309612407	951	3899	A prodrug with immunosuppresive properties, leflunomide is converted to an active metabolite that inhibits dihydroorotate dehydrogenase, a key enzyme of de novo pyrimidine synthesis. This agent also inhibits various protein tyrosine kinases, such as protein kinase C (PKC).	YBL105C	PKC1
SGTC_1643	st009866	20.2	µM	-1.0294918776508	0.136175152094809	no	2887	0.151624297306938	909	3156273		YOR207C	RET1
SGTC_281	1672-3440	14.9	µM	-1.03117146077747	0.135760788012586	no	2888	0.151230210698915	939	6833000			
SGTC_351	caspofungin	25	nM	-1.03249780426443	0.135434181278481	no	2889	0.150919487868511	909	9963413	Caspofungin is an echinocandin antifungal that acts by inhibiting 1,3-beta-D-glucan synthase required for cell wall biosynthesis.	YER133W | YER165W	GLC7 | PAB1
SGTC_721	1187-1332	279	µM	-1.03423727377453	0.13500666069909	no	2890	0.150512626419863	954	25730			
SGTC_773	4358-1457	44.6	µM	-1.03683234335387	0.134370575865806	no	2891	0.149906999637711	963	1186886			
SGTC_825	1988-2224	89.6	µM	-1.03882384169673	0.133883831797981	no	2892	0.149443335487832	936	1180859			
SGTC_3286	9117135	37.221	µM	-1.04005512581784	0.133583499376804	no	2893	0.14915714513569	927	3438150			
SGTC_3082	9117008	49.47	µM	-1.04316842846837	0.13282617648265	no	2894	0.148435146433638	938	41448529			
SGTC_864	0469-0573	172	µM	-1.04343502719472	0.132761463016233	no	2895	0.148373428975075	970	689425			
SGTC_1063	disulfiram	1.84	µM	-1.04364851317266	0.132709657655519	no	2896	0.148324019465493	950	3117	Disulfiram blocks the oxidation of alcohol through its irreversible inactivation of aldehyde dehydrogenase.		
SGTC_1174	0739-0097	51.1	µM	-1.04378686826175	0.132676091293237	no	2897	0.148292004238036	953	728447			
SGTC_711	k292-0785	179	µM	-1.04432270340204	0.132546147382267	no	2898	0.148168056152905	916	4146315			
SGTC_3254	9136651	49.47	µM	-1.04523803547282	0.132324375593034	no	2899	0.147956484150356	954	16454030			
SGTC_3324	9138759	60.749	µM	-1.04794598943285	0.131669775420196	no	2900	0.147331745934049	946	45595710			
SGTC_1656	st012921	11	µM	-1.04931322964732	0.131340119554563	no	2901	0.147016989538973	919	6732821			
SGTC_1873	rapamycin	2	nM	-1.04963575025003	0.131262439621141	no	2902	0.146942806900997	921	5284616	Rapamycin is an potent immunosuppressive and anticancer drug. It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin blocks downstream elements that result in cell cycle arrest in G1. that acts by inhibiting TOR. TOR (target of rapamycin) is a phosphatidylinositol kinase-related protein kinase that controls cell growth in response to nutrients.	YMR211W | YHR007C | YHR186C	DML1 | ERG11 | KOG1
SGTC_2996	9066192	71.4286	µM	-1.05390140315756	0.130238030326824	no	2903	0.145964030216228	925	6472854			
SGTC_1252	0493-0875	34.8	µM	-1.05490553823596	0.129997690786408	no	2904	0.145734264546243	931	3960963			
SGTC_596	1155-0152	116	µM	-1.05635652725179	0.129650939461945	no	2905	0.145402679700777	935	280313			
SGTC_1165	k072-0275	30.3	µM	-1.05721973405933	0.129444958075813	no	2906	0.145205657740858	944	6153523		YGL055W	OLE1
SGTC_771	0250-0039	27.3	µM	-1.06081583005016	0.128589285815999	no	2907	0.144386803341136	950	3005115			
SGTC_1854	st056233	32.9	µM	-1.06127547283401	0.128480199802219	no	2908	0.144282364446334	963	5393174			
SGTC_2782	7736369	71.43	µM	-1.06138717177806	0.128453700241228	no	2909	0.144256992181758	953	2950836		YOL077C	BRX1
SGTC_328	k915-0120	63.5	µM	-1.06300549120572	0.12807019428708	no	2910	0.143889730561104	935	6624543			
SGTC_1348	1493-0373	93.8	µM	-1.06313163834234	0.128040333652488	no	2911	0.143861129235778	955	3010129			
SGTC_413	propylparaben	100	µM	-1.06377978521986	0.127886985294976	no	2912	0.143714235450406	936	7175	A pharmaceutical preservative.		
SGTC_1153	4055-0057	267	µM	-1.06554186801604	0.127470730449198	no	2913	0.143315394809261	939	882706			
SGTC_337	1315-0038	354	µM	-1.06564933945566	0.127445373110738	no	2914	0.143291093272105	935	1626437			
SGTC_2710	st078562	53.7235	µM	-1.06725494159512	0.127066957116858	no	2915	0.142928364443121	966	17250908			
SGTC_33	0986-0033	35.816	µM	-1.06986758068897	0.12645287054745	no	2916	0.142339458748846	896	2848082			
SGTC_2277	7947813	106.88	µM	-1.07081725051815	0.126230169037324	no	2917	0.142125804423926	958	1246798			
SGTC_2400	5203494	178.7	µM	-1.071242528137	0.126130528341857	no	2918	0.142030196936965	938	6777674			
SGTC_2125	5246583	200	µM	-1.07369711265122	0.125556501365046	no	2919	0.14147922794484	947	835267			
SGTC_2326	6164455	177.58	µM	-1.07374333562016	0.125545709218643	no	2920	0.141468866406184	955	2888790			
SGTC_2776	terbinafine	19.92	µM	-1.0737526297094	0.125543539311325	no	2921	0.141466783065436	914	5282481	Terbinafine inhibits squalene epoxidase, an enzyme in the ergosterol biosynthetic pathway. Because ergosterol is part of the fungal cell membrane terbinafine is thought to change cell membrane permeability, ultimately resulting in fungal cell lysis.	YGR175C	ERG1
SGTC_3290	9121031	71.43	µM	-1.0755392867561	0.125126891369398	no	2922	0.141066676429791	938	17014854			
SGTC_1360	1598-0022	39.8	µM	-1.07605993826114	0.12500565748986	no	2923	0.140950225499262	942	761525			
SGTC_578	3460-0051	92	µM	-1.07639645121382	0.124927344001497	no	2924	0.140874994411645	975	2876744			
SGTC_21	0849-0113	22.993	µM	-1.0770214965058	0.124781974072058	no	2925	0.140735331118557	943	1560156			
SGTC_3147	9097027	49.47	µM	-1.07800598187114	0.124553247148232	no	2926	0.140515543309391	960	25236841			
SGTC_2493	resveratrol	26.09	µM	-1.07898630056815	0.124325779675059	no	2927	0.140296917370065	916	6255462	Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates SIRT1, a NAD+-dependent histone deacetylase.		
SGTC_805	3852-0218	479	µM	-1.0807154014863	0.12392527759613	no	2928	0.139911864977672	940	6615355			
SGTC_491	tetrandrine	80.3	µM	-1.08460368747384	0.123027956179683	no	2929	0.139048610563272	952	73078	Tetrandrine a bis-benzylisoquinoline alkaloid, a calcium channel blocker.		
SGTC_1752	st044819	83.042	µM	-1.08632625955675	0.122631888023555	no	2930	0.138667336579453	941	441209		YML126C	ERG13
SGTC_2304	7443016	91.4	µM	-1.08665217480911	0.122557051610673	no	2931	0.138595278716848	950	939854			
SGTC_1631	benzylvanillin	81.9	µM	-1.08721024702998	0.122428981910242	no	2932	0.13847195162333	920	75506			
SGTC_552	k242-0005	476	µM	-1.08768964966774	0.122319040786151	no	2933	0.138366069270617	961	4088318			
SGTC_2168	5727979	200	µM	-1.087874331505	0.122276706304977	no	2934	0.13832529459539	952	695210			
SGTC_248	streptozotocin	5.23457	mM	-1.0880054382907	0.122246659036452	no	2935	0.138296353371251	956	5300	DNA alkylating agent.		
SGTC_3019	9081971	49.47	µM	-1.08808216824011	0.122229076345232	no	2936	0.138279417500287	959	16451803			
SGTC_1341	1486-1360	280	µM	-1.09176912059087	0.121386301542432	no	2937	0.137467297516415	972	3976547			
SGTC_1102	cgs 12066b	26.1	µM	-1.09366009935824	0.120955644547872	no	2938	0.13705204005093	934	6438352	A 5-HT1B full agonist.		
SGTC_647	0140-0236	81	µM	-1.09366661718761	0.120954162020057	no	2939	0.137050610224445	966	990837			
SGTC_948	3448-0295	75.3	µM	-1.09459784386669	0.120742479120037	no	2940	0.136846430311423	933	678569			
SGTC_2540	epiandrosterone	100	µM	-1.09500405564063	0.12065022234214	no	2941	0.136757429851031	954	441302	A steroid.		
SGTC_780	0109-0199	192	µM	-1.09595004896629	0.120435565483202	no	2942	0.136550317376298	929	610414			
SGTC_3012	9080433	71.4286	µM	-1.09922162936434	0.119695280082503	no	2943	0.135835703280945	953	17688859			
SGTC_2927	9011802	47.9	µM	-1.10533382420792	0.118320837996888	no	2944	0.13450748336298	948	43912568			
SGTC_10	0279-0212	42.575	µM	-1.10578257264816	0.118220369933729	no	2945	0.134410319927005	968	39851		YBR002C	RER2
SGTC_289	k017-0060	526	µM	-1.10762212397658	0.11780915242389	no	2946	0.134012522287617	957	5512909			
SGTC_134	0269-0018	6.916	µM	-1.10787461157097	0.117752789862942	no	2947	0.133957985778982	954	4378915			
SGTC_589	1227-0070	34.1	µM	-1.10903232637743	0.117494598668808	no	2948	0.133708118403305	952	2841384			
SGTC_925	2064-1272	59.6	µM	-1.10974000663502	0.117336970792611	no	2949	0.133555539018532	967	6815817			
SGTC_262	fenpropimorph	62.5	µM	-1.11032507072366	0.117206767436063	no	2950	0.133429486737956	987	91695	Fenpropimorph is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in fungal cytoplasmic cell membranes. 	YDL196W	YDL196W
SGTC_2486	5283202	22.39	µM	-1.11116845563593	0.117019256112778	no	2951	0.133247923186216	954	1377751			
SGTC_1388	3346-4487	254	µM	-1.11141089471547	0.116965393543078	no	2952	0.133195762474794	982	3345614			
SGTC_1319	1306-0155	43.7	µM	-1.11157953694978	0.116927936744976	no	2953	0.133159487424911	954	3122360			
SGTC_2803	7707263	71.43	µM	-1.11275072400046	0.116668041193595	no	2954	0.132907751926122	956	2199229			
SGTC_1409	3909-8004	61.9	µM	-1.11479868627299	0.116214567239387	no	2955	0.132468349787845	953	2119279			
SGTC_1518	st038567	90.8	µM	-1.11613414006819	0.115919536414243	no	2956	0.132182360241172	968	77966			
SGTC_3159	9100096	49.47	µM	-1.11658403574425	0.115820264518211	no	2957	0.13208611029757	957	25236875			
SGTC_1187	1391-0724	117	µM	-1.12016667342149	0.1150318904964	no	2958	0.131321371393659	965	6997986			
SGTC_1278	0874-0585	172	µM	-1.12059209506582	0.114938528824927	no	2959	0.131230765680717	967	766306			
SGTC_369	0957-0393	4.5	µM	-1.12266223736	0.114484991240725	no	2960	0.130790485900958	967	6997992			
SGTC_2067	5224629	34.075	µM	-1.1238118299635	0.114233683324309	no	2961	0.130546430887451	955	2835000			
SGTC_2982	9019404	25.97	µM	-1.12588086124715	0.113782370845882	no	2962	0.130107975678157	945	22333232			
SGTC_1868	st057644	42.7	µM	-1.12633513298788	0.113683452088267	no	2963	0.130011846064283	982	688665			
SGTC_3192	9110362	49.47	µM	-1.12993450491752	0.112901846954984	no	2964	0.129251911618232	991	16649480			
SGTC_1414	3917-0015	5.4	µM	-1.13007219912947	0.112872022966999	no	2965	0.129222901547094	954	6618702			
SGTC_551	k048-0028	34.9	µM	-1.13076233735647	0.112722626661318	no	2966	0.129077567948677	961	6836383			
SGTC_2254	7938975	95.19	µM	-1.13234241745952	0.112381113791819	no	2967	0.128745251747972	975	2969277			
SGTC_2145	5634607	200	µM	-1.1365974951834	0.111465114208162	no	2968	0.127853293834063	979	308662			
SGTC_1448	4255-0083	152	µM	-1.13935078119936	0.110875263009717	no	2969	0.127278437944473	979	5399660			
SGTC_343	4130-2827	29.8	µM	-1.14110088854358	0.110501492526767	no	2970	0.126913970791375	967	1118244			
SGTC_1155	4088-0394	48.2	µM	-1.14207506866136	0.110293828606729	no	2971	0.126711408766619	949	2326248			
SGTC_2867	9039098	71.43	µM	-1.14352046522935	0.10998623238253	no	2972	0.12641128134303	948	6463460			
SGTC_3026	9090633	49.47	µM	-1.1438151679218	0.10992359203912	no	2973	0.126350149037623	956	25236842			
SGTC_1696	st025591	34.7925	µM	-1.14514356410914	0.109641553417051	no	2974	0.12607484595777	943	2787147			
SGTC_1966	st070145	16.1	µM	-1.14520624366774	0.109628258445452	no	2975	0.126061866290694	967	3748532			
SGTC_2105	5350118	200	µM	-1.1466301375314	0.1093265478407	no	2976	0.125767257660351	966	2133313			
SGTC_2431	5490079	200	µM	-1.14712931777596	0.109220917273645	no	2977	0.125664089306501	990	5722345			
SGTC_2668	2',4'-dihydroxychalcone	15.08	µM	-1.14931339977871	0.10875961022704	no	2978	0.125213387350811	998	5357218	A potent inhibitor of glutathione S-transferases.		
SGTC_39	0986-0283	58.349	µM	-1.14961390843165	0.108696248630436	no	2979	0.125151463546245	939	3110600		YBR109C | YER133W | YKL058W	CMD1 | GLC7 | TOA2
SGTC_388	3',4'-dichloroisocoumarin	16.7	µM	-1.15337651643005	0.107905157115178	no	2980	0.124377938028474	959	1609	A potent and irreversible inhibitor of serine proteases.		
SGTC_2497	7-hydroxyflavone	100	µM	-1.15561678644542	0.107436112328214	no	2981	0.123918969355344	961	5281894			
SGTC_2087	5276107	200	µM	-1.16071910018921	0.106373331109647	no	2982	0.122878075878466	959	144405			
SGTC_2526	patulin	37.61	µM	-1.16113312993379	0.106287425403818	no	2983	0.122793881802252	964	4696	Patulin is genotoxic and may be carcinogenic. It is an inhibitor of potassium uptake and an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase. It induces intra- and intermolecular protein crosslinking. 		
SGTC_3171	9103192	49.47	µM	-1.16410155630259	0.105672983229219	no	2984	0.122191429014401	985	13018434			
SGTC_2090	5301565	104.445	µM	-1.16411779902987	0.105669628185128	no	2985	0.122188138213228	966	2056344			
SGTC_756	0508-1999	28.3	µM	-1.16412466945202	0.105668209076603	no	2986	0.122186746274011	965	6753853			
SGTC_1268	0828-0275	2.46	µM	-1.16584236601373	0.10531384539199	no	2987	0.121839092293456	966	745337			
SGTC_1460	k062-0059	9.15	µM	-1.17343502205112	0.103757766177666	no	2988	0.120310699864785	941	1373085			
SGTC_768	0384-0033	77.3	µM	-1.17516161636039	0.103406248441074	no	2989	0.119965031655424	951	3965305		YMR134W	ERG29
SGTC_2147	5545932	89.7195	µM	-1.17554560954675	0.103328188822963	no	2990	0.119888250578162	990	797404			
SGTC_2713	st079149	53.4	µM	-1.17555964421512	0.103325336611944	no	2991	0.119885444942703	958	3103253			
SGTC_90	0870-0863	4.608	µM	-1.17798473555651	0.1028333526132	no	2992	0.119401345843172	989	1738164			
SGTC_728	3030-5151	22.5	µM	-1.17818138224685	0.102793533171969	no	2993	0.119362151583893	976	3125388			
SGTC_176	1486-1328	72.834	µM	-1.17823089349799	0.102783509290598	no	2994	0.119352284774335	954	22310231			
SGTC_3112	9123419	49.47	µM	-1.18126662737347	0.102170261092416	no	2995	0.118748410194711	987	17015854			
SGTC_280	3448-3607	3.04	µM	-1.18268031097087	0.101885593169774	no	2996	0.118467935104477	952	626179			
SGTC_2922	7999257	32.47	µM	-1.18314801447282	0.101791540753741	no	2997	0.118375245802182	988	2988377			
SGTC_659	k018-0002	107	µM	-1.18353315561115	0.101714138605977	no	2998	0.118298957176059	987	6797879		YHR007C	ERG11
SGTC_2098	5376439	882.5	nM	-1.18700443901645	0.101018444651101	no	2999	0.117612934782325	966	2844116			
SGTC_1261	0712-0010	12.7	µM	-1.19326626975984	0.099772269321189	no	3000	0.116382554050415	975	2840123			
SGTC_1649	st011737	51.3	µM	-1.19386466035862	0.0996537732767267	no	3001	0.116265456666544	912	1761035			
SGTC_52	0329-0193	875	nM	-1.19684384697528	0.0990653513275049	no	3002	0.115683712180257	981	3739292			
SGTC_1190	1486-1332	13	µM	-1.19856939357877	0.0987257013557018	no	3003	0.115347712537266	962	4150046			
SGTC_2165	5727197	32.143	µM	-1.19993967758173	0.0984565876336357	no	3004	0.115081384418103	970	1361712			
SGTC_1241	0364-0022	50.8	µM	-1.20017538441581	0.0984103507354163	no	3005	0.115035616597682	995	4563895			
SGTC_273	hydroxyurea	18.1	mM	-1.20498803039161	0.097469762902983	no	3006	0.114103961362713	987	3657	Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.	YDR047W	HEM12
SGTC_2694	st077685	81.9	µM	-1.20632301832478	0.0972100236892953	no	3007	0.11384648281398	970	2838096			
SGTC_2786	7743617	45.45	µM	-1.20937396634906	0.096618329654542	no	3008	0.113259602852794	964	583674			
SGTC_868	0527-0199	213	µM	-1.21297814461413	0.0959227571071953	no	3009	0.112569088277137	974	2849450			
SGTC_539	4859-0462	2.54	µM	-1.21410535232983	0.0957059744455349	no	3010	0.11235374820492	954	46499474		YNL221C | YBR257W	POP1 | POP4
SGTC_1600	coumarin 106	71.1	µM	-1.21496922365044	0.0955400803234403	no	3011	0.11218891486657	976	100336	A hepatotoxic, DNA x-linker.		
SGTC_1308	1187-1617	41.4	µM	-1.21551466288343	0.0954354455742345	no	3012	0.112084929895002	981	2882570			
SGTC_3279	9140807	49.47	µM	-1.21574315677934	0.0953916373526295	no	3013	0.112041389281735	995	45595718			
SGTC_2218	6965428	192.983	µM	-1.21648843525594	0.0952488509756184	no	3014	0.111899456921769	964	675684			
SGTC_1205	4161-2785	76	µM	-1.22091448699028	0.0944041141025391	no	3015	0.111059199376404	980	3498106			
SGTC_1559	coumarin 343	70.1	µM	-1.22307338922538	0.0939940856154801	no	3016	0.110650989225639	979	108770	A hepatotoxic, DNA x-linker.		
SGTC_274	sirtinol	40.1	µM	-1.23010045800022	0.0926685741851378	no	3017	0.109329744292066	971	6836442	NAD-dependent acetyltransferase inhibitor.		
SGTC_1334	1486-0610	236	µM	-1.23122993786981	0.0924568172279152	no	3018	0.109118438657008	952	3742339			
SGTC_1990	st072050	59.8	µM	-1.23159493618351	0.092388463276997	no	3019	0.109050216737869	975	17233948			
SGTC_367	0335-0881	7.1	µM	-1.23165962998809	0.0923763518436137	no	3020	0.10903812800289	994	23828853			
SGTC_1884	5633444	25	µM	-1.23289747471494	0.0921448391639741	no	3021	0.108807008869301	969	5724239			
SGTC_708	3448-5400	146	µM	-1.23424239944404	0.0918937866194817	no	3022	0.108556296225406	989	3462195			
SGTC_1119	parthenolide	318.541	nM	-1.23525463831986	0.0917051697997786	no	3023	0.108367875115905	1000	5702252	Parthenolide specifically inhibits HDAC1 (histone deacetylase 1) without affecting other class I/II HDACs.		
SGTC_1853	st056710	91.2	µM	-1.23534618301044	0.0916881258565967	no	3024	0.108350846330191	979	269167			
SGTC_1433	4060-0023	7.6	µM	-1.23846815269783	0.0911082762725144	no	3025	0.107771261867731	981	3840627			
SGTC_3103	9120822	49.47	µM	-1.2395574643639	0.0909065976208346	no	3026	0.107569560868272	980	17141819			
SGTC_2637	3-alpha-acetoxydihydrodeoxygedunin	100	µM	-1.24145055032844	0.0905568939016377	no	3027	0.10721967744833	963	6708514			
SGTC_1467	k284-1082	293	µM	-1.2422980075567	0.090400669826357	no	3028	0.107063315110793	983	3334705			
SGTC_243	5hr heat shock (37°C) + splitomicin	1	µM	-1.24839317003239	0.0892829517186752	no	3029	0.105943554500599	959	5269	Sir2p (silent information regulator) and HDAC inhibitor.		
SGTC_2005	4024620	188	µM	-1.24891272359155	0.0891881547532323	no	3030	0.10584849868183	989	236743			
SGTC_3161	9100388	49.47	µM	-1.25308713893066	0.0884292140237014	no	3031	0.105086998011997	993	25236368			
SGTC_2149	5554786	194.827	µM	-1.25507135517346	0.0880701600537777	no	3032	0.104726428969515	994	745063		YPR165W	RHO1
SGTC_571	k831-0106	44.2	µM	-1.25695043972448	0.0877311333494426	no	3033	0.104385791129285	969	4783639			
SGTC_3148	9097893	49.47	µM	-1.25789805734412	0.0875605327700175	no	3034	0.104214313179748	951	17174100			
SGTC_2509	methyl 7-deshydroxypyrogallin-4-carboxylate	54.59	µM	-1.2588105296133	0.0873964935190676	no	3035	0.104049388081944	948	5098884		YER133W | YBR257W | YHR062C	GLC7 | POP4 | RPP1
SGTC_980	1473-0395	201	µM	-1.26376502542356	0.0865098038947239	no	3036	0.103157188967532	976	768876			
SGTC_205	1486-1330	71.903	µM	-1.26766350538098	0.0858168471646551	no	3037	0.10245907138226	994	4118834			
SGTC_17	0960-0276	49.807	µM	-1.27083779688824	0.0852556906903129	no	3038	0.101893179604404	988	6821114			
SGTC_2406	ethylparaben	405.7	µM	-1.2714421753962	0.0851491599211819	no	3039	0.101785693270346	1011	8434	A possible steroid mimic.		
SGTC_1655	st012546	55.1	µM	-1.27176215744026	0.0850927986926998	no	3040	0.101728819155357	998	720985		YLR208W	SEC13
SGTC_3304	9125678	46.087	µM	-1.27241832901899	0.0849773089281427	no	3041	0.101612262555335	990	41316246		YGL155W | YKL019W | YKL058W	CDC43 | RAM2 | TOA2
SGTC_1055	3448-0672	86	µM	-1.27285282556289	0.0849008998591018	no	3042	0.101535135910733	978	748378			
SGTC_149	3970-0822	46.1	µM	-1.27310411789173	0.084856731968955	no	3043	0.10149054895732	978	3114250		YBL034C	STU1
SGTC_2392	N-(3-chlorophenyl)-6-oxo-1H-pyridine-3-carboxamide	200	µM	-1.2754133889324	0.0844516538517133	no	3044	0.101081481077759	999	803109			
SGTC_1375	2910-0797	186	µM	-1.27590805516558	0.0843650715265613	no	3045	0.100994011627454	994	742508			
SGTC_1777	st045864	34.765	µM	-1.27594450894801	0.0843586935912839	no	3046	0.100987567864033	1014	4691462			
SGTC_2091	4-phenylthiadiazole	200	µM	-1.27684716103458	0.0842008814175339	no	3047	0.100828105885079	992	270010			
SGTC_130	0136-0219	337.655	µM	-1.27865316791876	0.0838857995891035	no	3048	0.100509609107593	998	234244			
SGTC_421	streptovitacin	30	mM	-1.27879097779577	0.0838617932405604	no	3049	0.100485335942333	999	91467	include heat shock		
SGTC_2323	6148992	148.28	µM	-1.27952491222554	0.0837340294717925	no	3050	0.100356136322507	973	2888220		YOR207C | YHR062C | YKL042W	RET1 | RPP1 | SPC42
SGTC_2307	7538926	6.34	µM	-1.28003632071421	0.0836450896382877	no	3051	0.100266181198646	978	96582			
SGTC_943	3253-1379	105	µM	-1.28633950024673	0.0825547155906124	no	3052	0.0991623013335095	983	668464			
SGTC_1259	0671-0132	43	µM	-1.28658804474273	0.0825119407000322	no	3053	0.0991189564426917	977	X1259			
SGTC_2971	9092186	9.93	µM	-1.2869674349314	0.0824466792393082	no	3054	0.0990528194530292	975	25236400			
SGTC_3044	9093193	49.47	µM	-1.29105865301005	0.0817453885667927	no	3055	0.0983416699793981	981	25236277			
SGTC_3265	9137266	49.47	µM	-1.29396466525618	0.0812499962339103	no	3056	0.0978388131146564	960	17224265			
SGTC_2558	carylophyllene oxide	100	µM	-1.29547837672283	0.0809928503775035	no	3057	0.097577627985789	1000	6708694	An oxygenated terpenoid and antifungal agent.		
SGTC_2312	7706453	155.7	µM	-1.29617292820353	0.0808750673466894	no	3058	0.0974579570582469	995	976098			
SGTC_2719	novobiocin	32.65	µM	-1.29785901517032	0.0805896763512009	no	3059	0.0971678929239838	1004	54675769	An antibiotic compound derived from Streptomyces niveus, novobiocin has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, inhibiting DNA replication.		
SGTC_1378	2093-0007	380	nM	-1.30154220961652	0.0799688969641557	no	3060	0.096536463152788	1004	3618014			
SGTC_1959	st077091	55.8	µM	-1.30306806756791	0.0797127849692088	no	3061	0.0962757621104292	978	821356		YKL052C	ASK1
SGTC_2816	7982706	58.44	µM	-1.30333018406166	0.07966885179514	no	3062	0.0962310302268916	988	2981853			
SGTC_740	k014-0057	261	µM	-1.30487475005211	0.0794103400328801	no	3063	0.095967750214503	990	4012779			
SGTC_1458	k015-0034	6.33	µM	-1.30527293150341	0.0793438000266085	no	3064	0.0958999638937571	1008	3598957			
SGTC_969	1313-0238	134	µM	-1.31550759637044	0.0776479369398758	no	3065	0.0941696830210317	985	5212874			
SGTC_1479	0549-0158	134	µM	-1.31731270171464	0.0773517107417572	no	3066	0.0938669146813587	1009	5440202			
SGTC_9	0092-0002	10.449	µM	-1.31736577380958	0.077343014371884	no	3067	0.0938580238425053	993	759368			
SGTC_2464	5717415	7.67	µM	-1.31922720077993	0.0770384713745274	no	3068	0.0935465836192821	991	5285744			
SGTC_2203	7227154	166.4	µM	-1.32172674301477	0.0766309627277196	no	3069	0.0931295800289132	1000	896304			
SGTC_2039	Aminomethylbenzodioxan	200	µM	-1.32195495339443	0.076593838661239	no	3070	0.093091575787269	1007	15053			
SGTC_131	0141-0277	33.849	µM	-1.33444884511874	0.0745822040827781	no	3071	0.0910284005842116	1018	1547771			
SGTC_1488	4013-0813	75.9	µM	-1.33969072200069	0.0737503209919863	no	3072	0.0901729575850834	980	2910057			
SGTC_1284	0929-0043	16	µM	-1.34246010308718	0.0733136945934002	no	3073	0.0897234290963465	996	1239883			
SGTC_296	1222-0039	74.9	µM	-1.34435715487238	0.0730157445212765	no	3074	0.0894164607968475	1011	5984176			
SGTC_2163	5671233	125	µM	-1.34773218677897	0.0724879558295924	no	3075	0.0888722678959474	970	701023			
SGTC_1391	3442-0225	151	µM	-1.34876609870386	0.0723268584893839	no	3076	0.088706053499452	1003	5227075			
SGTC_1648	st011736	69.8	µM	-1.35061713021746	0.0720391284015849	no	3077	0.0884090552648648	1010	2855514			
SGTC_984	1492-0255	2.91	µM	-1.35463001159705	0.0714183679544455	no	3078	0.0877677333283258	1011	1585198			
SGTC_227	fluconazole	33.516	µM	-1.35489278741377	0.0713778623153644	no	3079	0.0877258589767539	1001	3365	Fluconazole is a triazole antifungal; inhibits lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YCR093W | YER133W | YOR174W | YJL195C	CDC39 | GLC7 | MED4 | YJL195C
SGTC_2120	5538279	151.968	µM	-1.35973790533082	0.0706341664992376	no	3080	0.0869564392125196	1016	2058197			
SGTC_3229	9132204	49.47	µM	-1.36133084445116	0.0703909653500885	no	3081	0.0867045798727041	1025	17682924			
SGTC_2023	5144124	124	µM	-1.36364389070348	0.0700389690749733	no	3082	0.0863398356300164	986	2830192			
SGTC_2926	9010726	65.15	µM	-1.36503609453772	0.0698277591315179	no	3083	0.0861208528730394	1011	2994293			
SGTC_2911	7942208	15.64	µM	-1.3664143473381	0.0696191488776237	no	3084	0.0859044740385099	974	1243384			
SGTC_849	0386-0493	241	µM	-1.36653998100064	0.069600157044998	no	3085	0.0858847704302521	1010	726119			
SGTC_2079	5212404	121	µM	-1.3676428218842	0.0694336135732147	no	3086	0.085711952811446	999	758462			
SGTC_2016	5121758	140	µM	-1.37302546911958	0.0686251644088479	no	3087	0.0848722145290991	982	2795203			
SGTC_258	haloperidol	50.781	µM	-1.37336484352282	0.0685744362416614	no	3088	0.0848194767043835	999	3559	Haloperidol is a D2, D3, and D4 dopamine antagonist of the typical antipsychotic class of medications. It is a butyrophenone derivative and has pharmacological effects similar to the phenothiazines.		
SGTC_322	k048-0136	19.3	µM	-1.37419033455893	0.0684511662779197	no	3089	0.0846913003012686	1014	6823282			
SGTC_3041	9091929	49.47	µM	-1.37685084305039	0.0680550377170729	no	3090	0.0842791839026021	996	25236887			
SGTC_2373	9071805	200	µM	-1.37822814918612	0.0678506642305394	no	3091	0.0840664294276953	1020	10149009			
SGTC_2548	3',4'-didesmethyl-5-deshydroxy-3'-ethoxyscleroin	19.94	µM	-1.3787043600765	0.0677801113978991	no	3092	0.0839929623288777	961	4000243			
SGTC_1645	Cervolide	78	µM	-1.37918650051601	0.0677087378169262	no	3093	0.0839186295766246	1010	23173	A fragrance.		
SGTC_914	3820-6779	408	µM	-1.380866611882	0.0674604764128228	no	3094	0.0836599887615621	993	2893481			
SGTC_812	4251-0442	148	µM	-1.38090527190245	0.067454772111914	no	3095	0.0836540443920126	1017	5723007			
SGTC_2945	9067681	61.76	µM	-1.38267015450591	0.0671947597469119	no	3096	0.0833830136113629	1019	16456930			
SGTC_1124	fisetin	1.16336	µM	-1.38325175683565	0.0671092448185035	no	3097	0.0832938424299406	1007	5281614	Fisetin is a natural flavonol thought to be a sirtuin-activating compound; demonstrated to alleviate aging effects in the model organisms yeast S. cerevisiae, the nematode C. elegans and the fruit fly D. melanogaster.		
SGTC_1681	tripelennamine	100	µM	-1.38521812413119	0.0668207464683042	no	3098	0.0829928902034442	986	9066	Tripelennamine acts primarily as an antihistamine, or H1 receptor antagonist.		
SGTC_55	0767-0285	6.563	µM	-1.38867729332474	0.0663155595725694	no	3099	0.0824654509625026	991	3116166			
SGTC_112	phenothiazine	287.218	µM	-1.39089237311003	0.0659936196803466	no	3100	0.0821290329679543	1002	7108	Phenothiazine is an organic compound that occurs in various antipsychotic and antihistaminic drugs. 		
SGTC_1622	st003707	19.4	µM	-1.39206848693447	0.0658231760874472	no	3101	0.0819508299339994	983	10140899			
SGTC_3351	9150312	21.596	µM	-1.39693582238182	0.0651214226198223	no	3102	0.0812164355443826	1008	4904905			
SGTC_1571	st070080	73.4	µM	-1.40148929239078	0.0644701905287505	no	3103	0.0805339036453373	989	4315245			
SGTC_1669	st015249	58.4	µM	-1.40362236386049	0.0641668666073853	no	3104	0.080215665989448	1023	722793			
SGTC_111	0083-0039	52.457	µM	-1.4051566572878	0.0639493760403534	no	3105	0.0799873497097006	992	759313			
SGTC_169	k015-0017	16.025	µM	-1.40805220350313	0.0635404861769457	no	3106	0.0795578062837514	1032	1840002			
SGTC_2849	9019321	12.99	µM	-1.41001546291154	0.0632644070806061	no	3107	0.0792675585571503	997	16489627			
SGTC_2194	5927483	104.545	µM	-1.41068013626324	0.0631711507462631	no	3108	0.0791694752935395	1005	760979			
SGTC_1960	st011366	51.8	µM	-1.42459441575779	0.0612433979700343	no	3109	0.0771372375893865	1002	3972846			
SGTC_458	nppb	133	µM	-1.4271938963483	0.0608884030518076	no	3110	0.076762006671784	1022	4549	A chloride channel blocker.		
SGTC_3027	9089541	49.47	µM	-1.42799080311955	0.0607798972615364	no	3111	0.0766472528408878	1011	9943819			
SGTC_970	1315-0089	19.5	µM	-1.43284958003018	0.0601216008366841	no	3112	0.0759504144261022	998	6811083		YLR033W	RSC58
SGTC_2260	7964312	200	µM	-1.43302293651951	0.0600982170008705	no	3113	0.075925641325429	1022	231951			
SGTC_2467	5474540	200	µM	-1.43396850260405	0.0599707961261829	no	3114	0.0757906257295907	993	5413519			
SGTC_867	0518-0118	155	µM	-1.43569176908357	0.0597391195790067	no	3115	0.075545034196031	987	6848158			
SGTC_1733	st037357	54.9	µM	-1.43591971422021	0.0597085271372043	no	3116	0.0755125940290559	1004	1272339		YGL099W	LSG1
SGTC_420	mitomycin C	81.9	mM	-1.43881765910929	0.0593206640586879	no	3117	0.0751010958582427	983	5746	Mitomycin is a bifunctional and trifunctional alkylating agent, cross-links DNA inhibiting DNA synthesis and function. Mitomycin is cell cycle phase-nonspecific.		
SGTC_1126	isoteolin	1.0172	µM	-1.43962552219393	0.0592128919307771	no	3118	0.0749866874360395	1001	133323			
SGTC_1089	terbinafine	2.25	µM	-1.44175402553887	0.0589296763481616	no	3119	0.0746858883618215	1000	5282481	Terbinafine inhibits squalene epoxidase, an enzyme in the ergosterol biosynthetic pathway. Because ergosterol is part of the fungal cell membrane terbinafine is thought to change cell membrane permeability, ultimately resulting in fungal cell lysis.	YGR175C	ERG1
SGTC_1943	st076331	65.2	µM	-1.44251527044865	0.058828644622793	no	3120	0.0745785334311848	1025	24208415			
SGTC_1193	1488-0126	41.5	µM	-1.44688027943283	0.0582519466440489	no	3121	0.0739652286392807	1008	1384710			
SGTC_621	3584-0052	32.1	µM	-1.4510432505685	0.057706088099706	no	3122	0.0733839085832487	1015	2273927			
SGTC_880	0833-0487	87.2	µM	-1.45210015705959	0.0575681462314785	no	3123	0.0732368791447983	1017	76075			
SGTC_3292	9120825	59.784	µM	-1.45229222641596	0.0575431062214638	no	3124	0.073210184015733	1000	24824900			
SGTC_2214	7179297	48.276	µM	-1.45664915211872	0.0569773935401323	no	3125	0.0726066262042014	1026	769744			
SGTC_5	0352-0601	109.883	µM	-1.45789395209257	0.0568165728693325	no	3126	0.0724348879596799	998	762456			
SGTC_238	5hr heat shock (37°C) + nsc-638432	8.929	µM	-1.45941521349039	0.0566205207085864	no	3127	0.0722254306143767	1032	368090			
SGTC_2432	5630864	12.22	µM	-1.46321022181688	0.056133763108927	no	3128	0.0717049323244208	1013	5714970			
SGTC_2040	5100729	123	µM	-1.46353971061593	0.0560916581843499	no	3129	0.071659877922748	1029	11840		YJR013W | YDR381W	GPI14 | YRA1
SGTC_564	3555-0129	330	µM	-1.46381706128272	0.0560562352304401	no	3130	0.0716219697430353	988	563260			
SGTC_1242	0402-0103	60.1	µM	-1.46691324353924	0.0556619906357679	no	3131	0.0711998286881492	1003	432868			
SGTC_2043	5101342	149	µM	-1.46695756099251	0.0556563635109119	no	3132	0.0711938002358674	1025	678451			
SGTC_2912	7964298	10.93	µM	-1.467165945267	0.0556299103302263	no	3133	0.0711654592159033	990	2975850			
SGTC_3267	9137951	49.47	µM	-1.4699545808145	0.0552768633197542	no	3134	0.0707870277750719	1057	16643986			
SGTC_159	3970-0959	50	µM	-1.47060814094147	0.0551943777613007	no	3135	0.0706985605288936	1001	6615653			
SGTC_2314	7727897	200	µM	-1.47625764892355	0.054485402219072	no	3136	0.0699373693753164	985	900724			
SGTC_1413	3910-0535	34.4	µM	-1.48177037811458	0.0538005538301108	no	3137	0.069200701725929	1018	2876951			
SGTC_2366	9070441	60.58	µM	-1.48185315323239	0.0537903228343503	no	3138	0.0691896861978664	1009	6837235			
SGTC_1724	st037281	8.293	µM	-1.48477171140309	0.0534305732231148	no	3139	0.0688021539742746	990	574124		YDL195W	SEC31
SGTC_2846	9008642	19.48	µM	-1.48728078234334	0.0531228246032787	no	3140	0.0684703339916609	1039	2992898			
SGTC_903	1134-0042	114	µM	-1.48787799083201	0.0530497818137269	no	3141	0.0683915364697303	1007	701009			
SGTC_1547	harmine	94.2	µM	-1.48942669195699	0.0528607358198018	no	3142	0.0681875220724445	995	5280953	A monoamine oxidase inhibitor	YHR072W	ERG7
SGTC_2315	7733312	200	µM	-1.48993028444177	0.0527993788380421	no	3143	0.0681212838377456	1013	726316			
SGTC_2064	5220758	200	µM	-1.49136355893112	0.0526250599478056	no	3144	0.0679330350537653	1005	788518			
SGTC_1682	st012968	530	nM	-1.49442745282205	0.0522539523522356	no	3145	0.067531965304284	1001	24207270			
SGTC_924	2046-0044	21.3	µM	-1.49675801956453	0.0519730615070442	no	3146	0.0672281166637246	1011	3623589			
SGTC_3077	9117319	49.47	µM	-1.5015866924754	0.0513949055598879	no	3147	0.0666019411210034	1035	17154678			
SGTC_74	000s-0487	160.283	µM	-1.50212005566617	0.051331358856559	no	3148	0.0665330530998985	1005	677548			
SGTC_3029	9088683	49.47	µM	-1.503720895067	0.051141004668016	no	3149	0.0663266233790201	1015	25236615			
SGTC_1374	2889-5571	141	µM	-1.50784730065285	0.0506529274792719	no	3150	0.0657968064764056	997	2853281			
SGTC_2856	9022925	19.48	µM	-1.50818111471228	0.0506136062309077	no	3151	0.065754089681036	1021	4944862			
SGTC_640	3381-0960	37.1	µM	-1.5105753622905	0.0503322906744248	no	3152	0.0654483375527022	1035	1745025			
SGTC_2759	disulfiram	3.38	µM	-1.51080694951197	0.0503051462249719	no	3153	0.0654188217987058	998	3117	Disulfiram blocks the oxidation of alcohol through its irreversible inactivation of aldehyde dehydrogenase.		
SGTC_253	dyclonine	31.25	µM	-1.51138372686792	0.0502375925854301	no	3154	0.0653453564939098	1027	3180	An oral anasthetic.		
SGTC_3356	9151811	4.48	µM	-1.51305690787047	0.0500420344060367	no	3155	0.0651326021131605	1029	1859254		YPR165W	RHO1
SGTC_580	1123-0028	41	µM	-1.51660182248856	0.0496297170182967	no	3156	0.0646836224938541	1045	1677248		YPR107C	YTH1
SGTC_471	1-acyl-paf	4	µM	-1.51705288890442	0.0495774473973699	no	3157	0.0646266656727358	1030	16759367			
SGTC_2888	9058547	12.99	µM	-1.51814085981275	0.0494515539894327	no	3158	0.0644894462757262	1012	16476514			
SGTC_202	3594-0513	34.79	µM	-1.52299709526251	0.0488927283601607	no	3159	0.063879716074457	1040	708429			
SGTC_2655	perillic acid	100	µM	-1.52907295037508	0.0482006752580434	no	3160	0.0631231801023374	1043	5702197	An apoptosis inducer.		
SGTC_171	k064-0041	9.68	µM	-1.5301820700746	0.0480751941198297	no	3161	0.0629858341020374	994	53325			
SGTC_1365	1672-3266	55.4	µM	-1.53494194920353	0.0475396469461596	no	3162	0.0623990440242178	998	6415873			
SGTC_2559	tetrahydrosappanone a trimethyl ether	100	µM	-1.53501174467773	0.0475318297628212	no	3163	0.062390471573342	1044	6708784	An antioxidant flavonoid		
SGTC_2907	7721985	69.9	µM	-1.53598906117417	0.0474224771748879	no	3164	0.0622705316085805	1031	3267881			
SGTC_2280	7785178	200	µM	-1.54600255869325	0.0463136364153868	no	3165	0.0610519749377378	1013	2954328			
SGTC_1482	3346-2049	8.48	µM	-1.5475809269065	0.0461407710624325	no	3166	0.0608616132124567	1028	3826804			
SGTC_2241	6772625	37.8075	µM	-1.5541984705802	0.0454216408372833	no	3167	0.0600685411141805	1007	2285411			
SGTC_3078	9116413	49.47	µM	-1.55611935832539	0.0452145939473107	no	3168	0.059839856279987	1003	17177322			
SGTC_3196	9111891	49.47	µM	-1.564750211126	0.0442936525356812	no	3169	0.0588207450744835	1040	18891510			
SGTC_675	1309-0189	238	µM	-1.56630358332115	0.0441295189494322	no	3170	0.0586387812617487	1027	4246530			
SGTC_1139	k015-0024	46.9	µM	-1.56838551480642	0.0439103057215225	no	3171	0.0583955947705193	1033	2766652			
SGTC_2157	5649910	96.377	µM	-1.57101184450884	0.043635024784544	no	3172	0.058089948787139	1032	2858091			
SGTC_1816	st051957	91.6	µM	-1.58006713577219	0.0426965494594233	no	3173	0.0570457462772775	1054	674121			
SGTC_233	rapamycin	362	pM	-1.58108431890099	0.0425921574556369	no	3174	0.0569293798388627	1045	5284616	Rapamycin is an potent immunosuppressive and anticancer drug. It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin blocks downstream elements that result in cell cycle arrest in G1. that acts by inhibiting TOR. TOR (target of rapamycin) is a phosphatidylinositol kinase-related protein kinase that controls cell growth in response to nutrients.	YBR088C | YGR114C	POL30 | YGR114C
SGTC_3138	9097216	49.47	µM	-1.58152243733847	0.0425472576411892	no	3175	0.0568793164203993	1029	25237486			
SGTC_2155	5570423	76	µM	-1.5828553955656	0.0424108870419553	no	3176	0.0567272136099679	1042	797402			
SGTC_1192	1488-0095	21.4	µM	-1.586950628671	0.0419941274884422	no	3177	0.0562619134682342	1038	915875			
SGTC_1474	0330-0125	5.35	µM	-1.59359043114826	0.0413254652814578	no	3178	0.0555138995456376	1053	X1474			
SGTC_1189	1431-2119	7.28	µM	-1.59456091373274	0.0412284595447116	no	3179	0.0554052294811952	1035	3107275			
SGTC_2022	5136654	200	µM	-1.59694218926206	0.0409912183852688	no	3180	0.0551392971493367	1031	1713771			
SGTC_1740	st038286	13.222	µM	-1.60758731076314	0.0399441727197646	no	3181	0.0539627965785923	1021	716786			
SGTC_1156	4092-0367	4.88	µM	-1.60944343104873	0.0397638510777675	no	3182	0.0537597075259676	1028	1357585			
SGTC_277	nystatin	15.5	µM	-1.6104362864938	0.0396676674291298	no	3183	0.0536513221212353	1053	11468707	Nystatin is a polyene antifungal that binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.		
SGTC_2258	7960471	200	µM	-1.61124882871791	0.0395890926082765	no	3184	0.0535627495244014	1050	2974708			
SGTC_533	1222-0222	6.71	µM	-1.61232879150516	0.0394848535410207	no	3185	0.0534452056311371	1043	3982874			
SGTC_2962	9082311	13.18	µM	-1.61382809789563	0.0393405092600584	no	3186	0.0532823590632407	1035	16459453			
SGTC_518	1021-0119	62.6	µM	-1.61486254962147	0.0392411689514366	no	3187	0.0531702319734674	1025	1097762			
SGTC_1464	k208-0027	110	µM	-1.61729196278253	0.0390086705056598	no	3188	0.0529076366839619	1017	X1464			
SGTC_1699	st031318	29.054	µM	-1.62328878349114	0.0384395646713332	no	3189	0.0522638430816366	1032	5340658			
SGTC_145	3737-0113	38.366	µM	-1.62341977026522	0.0384272097948833	no	3190	0.052249850626428	1028	6849351			
SGTC_870	0573-2213	57.6	µM	-1.62862068853025	0.0379392610240691	no	3191	0.0516966709257113	1030	3916321			
SGTC_507	nimesulide	162	µM	-1.63857468069331	0.0370194791815895	no	3192	0.0506509344996868	1038	4495	A COX2 inhibitor.		
SGTC_2001	4023502	57.655	µM	-1.64076960830804	0.0368191331040953	no	3193	0.0504226246302683	1015	108941		YCR052W	RSC6
SGTC_730	1436-0052	41.2	µM	-1.64653946669878	0.0362967045031342	no	3194	0.0498263707650782	1034	768764		YPL266W | YMR113W | YOL144W | YBR192W	DIM1 | FOL3 | NOP8 | RIM2
SGTC_2573	2',4'-dihydroxychalcone	15.04	µM	-1.64909421756279	0.0360673321216205	no	3195	0.0495641670475747	1017	5357218	A potent inhibitor of glutathione S-transferases.	YPR085C	ASA1
SGTC_336	4111-0029	111	µM	-1.64921193721545	0.0360567916106458	no	3196	0.0495521116257312	1042	3131175			
SGTC_1991	st073000	8.92	µM	-1.66136268929675	0.0349823175242348	no	3197	0.0483203132528614	1047	4301969		YIL048W	NEO1
SGTC_1209	2323-2347	50.3	µM	-1.66223722163998	0.0349060085387318	no	3198	0.0482326098012586	1008	5412760			
SGTC_828	2074-0507	139	µM	-1.66435965685631	0.0347213795119628	no	3199	0.048020288575284	1026	X828			
SGTC_247	mechlorethamine	29.705	µM	-1.66502407570379	0.0346637473065141	no	3200	0.0479539763191033	1029	22133593	Mechlorethamine, a bifunctional alkylating agent, binds to the N7 position on guanine inducing DNA damage and interstrand cross-links.		
SGTC_2109	5483026	200	µM	-1.6657945792935	0.0345970116336851	no	3201	0.0478771680956757	1026	759335			
SGTC_418	lividomycin a	100	µM	-1.6729883674444	0.0339790140706061	no	3202	0.0471647930303369	1038	72394	An antibiotic.		
SGTC_1286	0929-0070	131	µM	-1.67365062926601	0.0339225803345129	no	3203	0.0470996410039458	1042	1420408			
SGTC_1570	verbenone	133	µM	-1.68113593799061	0.0332900738681958	no	3204	0.0463682566389483	1057	29025	A natural terpanoid with antifungal properties.		
SGTC_1137	ixabepilone	100	µM	-1.68412772995923	0.033040000101606	no	3205	0.0460784931563747	1036	154225	A novel microtubule stabilizer.		
SGTC_1353	1498-1206	8.11	µM	-1.69302510386541	0.0323054313101297	no	3206	0.0452253444541943	934	6756808			
SGTC_1715	st032160	10.2275	µM	-1.69977977757942	0.0317568087516608	no	3207	0.0445861783513392	1032	5289825			
SGTC_2379	9035213	200	µM	-1.69994995616174	0.0317430866772378	no	3208	0.0445701695355684	1037	646551			
SGTC_3247	9135149	49.47	µM	-1.70428463834428	0.0313952148743235	no	3209	0.0441639617249229	1027	8934436		YOR116C	RPO31
SGTC_324	1315-0088	19.6	µM	-1.71062015506835	0.0308924453037921	no	3210	0.0435756279197755	1043	6787421			
SGTC_3281	9140613	49.47	µM	-1.7123965826152	0.0307526750962317	no	3211	0.0434118042110955	1024	16013766			
SGTC_897	1000-0139	31.4	µM	-1.7128536906087	0.0307167944281526	no	3212	0.0433697298427675	1046	6151020			
SGTC_888	0916-0002	6.97	µM	-1.71617106351065	0.0304574347315956	no	3213	0.043065368852567	1057	2802138		YIL048W	NEO1
SGTC_376	3970-0862	59.1	µM	-1.71874289611219	0.030257613801736	no	3214	0.0428305987464064	1026	3135186			
SGTC_1418	3966-3099	2.4	µM	-1.72773600787877	0.0295674097306975	no	3215	0.042017782387375	1036	740335			
SGTC_1767	st044992	70.3	µM	-1.72851299952951	0.0295083953902213	no	3216	0.0419481462274617	1046	9600693			
SGTC_1640	st009078	66.4	µM	-1.73025703326859	0.0293762879269658	no	3217	0.0417921812619914	1037	690618			
SGTC_1233	0325-0408	14.2	µM	-1.73275044627639	0.0291882695969339	no	3218	0.0415700169792017	1048	12874			
SGTC_2702	st077768	96.8	µM	-1.73321772963872	0.0291531450825826	no	3219	0.0415284884598006	1039	6484119			
SGTC_107	0358-0022	2.6945	µM	-1.74019043964191	0.028633182161943	no	3220	0.0409127918965406	1061	521106		YGL093W | YPR107C	SPC105 | YTH1
SGTC_1237	0330-0133	46.1	µM	-1.74210513541632	0.0284917584985816	no	3221	0.0407450245810423	1040	X1237		YHR072W	ERG7
SGTC_370	0180-0345	38.7	µM	-1.75390133454555	0.0276332286699491	no	3222	0.0397237074476365	1018	3989527			
SGTC_1695	st026914	34.495	µM	-1.75405249317848	0.0276223688019317	no	3223	0.0397107564373932	1059	3289191			
SGTC_2845	9003024	42.97	µM	-1.75545578740292	0.0275217199857244	no	3224	0.0395906884240585	1037	2990173			
SGTC_1075	aripiprazole	15.2	µM	-1.7561543604636	0.0274717301556036	no	3225	0.039531027602475	1060	60795	An atypical antipschotic.	YIL048W	NEO1
SGTC_3274	9138298	49.47	µM	-1.76220571852428	0.027041855881654	no	3226	0.0390172731379349	1057	17015756			
SGTC_440	fluspirilene	35.1	µM	-1.77050406059661	0.0264615015645081	no	3227	0.0383216042751795	1047	3396	An atypical antipsychotic.		
SGTC_2492	derrusnin	100	µM	-1.77194593736707	0.0263617312189361	no	3228	0.0382017659540697	1055	1715307	Part of coumarin class of compounds.		
SGTC_1543	azetidyl-2-carboxylic acid	198	µM	-1.77954843419412	0.0258408635726802	no	3229	0.0375749458270675	1052	16486	A toxic proline analog.		
SGTC_2387	9077560	195.08	µM	-1.79755681637305	0.0246413390790688	no	3230	0.0361236334154691	1043	5303272			
SGTC_147	4466-0538	29.23	µM	-1.79928985788527	0.0245284077523088	no	3231	0.0359864207890935	1050	6742687		YHR072W	ERG7
SGTC_99	0109-0120	622.8	µM	-1.80213345643743	0.0243440496872288	no	3232	0.0357622055204424	1050	759414			
SGTC_483	fpl-64176	144	µM	-1.80403926676678	0.0242211432259264	no	3233	0.0356125757328518	1063	3423			
SGTC_2875	9039966	71.43	µM	-1.80675338218886	0.0240470087593115	no	3234	0.0354003701396542	1055	6463691			
SGTC_1905	st060207	84.5	µM	-1.80721567007601	0.02401745400009	no	3235	0.0353643292982996	1037	1948547			
SGTC_232	clozapine	119	µM	-1.82004739916985	0.0232092026041726	no	3236	0.0343758934735972	1068	2818	An adrenergic, cholinergic, GABAA and histaminergic receptor agonist.	YIL048W	NEO1
SGTC_1249	0481-0015	10.2	µM	-1.82139929181839	0.0231253979849603	no	3237	0.0342730913773677	1043	4227577			
SGTC_3072	9116419	49.47	µM	-1.82163528335084	0.0231107948834642	no	3238	0.0342551717828011	1042	17170162			
SGTC_2007	4011539	71.82	µM	-1.82852148578518	0.0226880848309645	no	3239	0.0337356620430074	1044	45595301			
SGTC_2135	5326629	150.42	µM	-1.83106687972967	0.0225334940518167	no	3240	0.0335452806420328	1054	5020077			
SGTC_203	k066-0004	30.888	µM	-1.83424186733738	0.0223419115412649	no	3241	0.0333090495712984	1073	6795412			
SGTC_1211	1056-0033	32.3	µM	-1.83558025827025	0.0222615641119691	no	3242	0.0332098795549247	1040	6741922			
SGTC_2293	7624732	200	µM	-1.84139681754246	0.02191520582579	no	3243	0.0327817144221379	1044	894453			
SGTC_572	0960-0087	17.7	µM	-1.84313682874432	0.0218124819271807	no	3244	0.0326545176753505	1055	6796365			
SGTC_358	0075-0058	9.45	µM	-1.85038725216888	0.0213888106894132	no	3245	0.032128877511655	1066	1069125			
SGTC_3236	9132701	49.47	µM	-1.85854293993498	0.02092057668364	no	3246	0.031545975743465	1064	24282524			
SGTC_2189	6047310	154.431	µM	-1.86308254992005	0.0206637281298231	no	3247	0.0312253264678425	1055	711535			
SGTC_1109	tnp00067	928.257	nM	-1.86390381186992	0.0206175480472395	no	3248	0.0311676066695571	1058	676295			
SGTC_2690	usnic acid	100	µM	-1.8733073449579	0.0200949833846717	no	3249	0.0305129781026193	1060	5646	An anti-infective, antifungal and antitrichomonal agent.		
SGTC_1769	st044406	64.4	µM	-1.87700957315191	0.0198923507630763	no	3250	0.0302583909019606	1073	670903			
SGTC_1077	5-fluorocytosine	377	nM	-1.88622676296794	0.0193953886951147	no	3251	0.0296322017579695	1057	3366	The mechanism of 5-fluorocytosine (5-FC) is identical to 5-fluorouracil (5-FU) and acts by inhibiting thymidylate synthetase and through metabolism into cytotoxic ribonucleotides and deoxyribonucleotides that can be incorporated into DNA and RNA. In addition, the drug has been shown to inhibit the essential ribonuclease activity of the exosome complex. The specificity of 5-FC for fungi is due to the requirement for the fungal specific cytosine permease in addition to cytosine deaminase that acts to convert 5-FC to 5-FU.		
SGTC_894	0960-0238	55.9	µM	-1.89235864532482	0.0190706525764183	no	3252	0.0292216060358427	1051	6741907		YDL195W	SEC31
SGTC_2676	harmalol	100	µM	-1.89769194592384	0.0187919787559244	no	3253	0.0288683370815403	1045	5459187	A monoamine oxidase inhibitor		
SGTC_259	usnic acid	108.925	µM	-1.91217071151462	0.018052853524695	no	3254	0.0279271507281879	1074	5646	An anti-infective, antifungal and antitrichomonal agent.		
SGTC_2934	9036370	36.88	µM	-1.91313845049436	0.0180043476190722	no	3255	0.0278651652460044	1037	6462800			
SGTC_1274	0865-0114	173	µM	-1.91775537484639	0.0177744607809247	no	3256	0.0275710183063179	1062	870624			
SGTC_543	3844-1095	191	µM	-1.91925595950195	0.01770028463407	no	3257	0.0274759743196174	1060	4230703			
SGTC_1651	st011928	86.1	µM	-1.92438117654823	0.0174489260212946	no	3258	0.0271534110621832	1068	720198			
SGTC_1822	st052468	42	µM	-1.92810027778337	0.0172684421721	no	3259	0.0269213272249023	1058	2873678			
SGTC_3263	9137018	49.47	µM	-1.92817120641264	0.0172650156404365	no	3260	0.0269169171931155	1049	43844957			
SGTC_1017	4239-0030	168	µM	-1.94899710474747	0.0162837280291707	no	3261	0.0256478852392948	1054	1149593			
SGTC_2031	5180455	200	µM	-1.95117437462711	0.0161839516675461	no	3262	0.0255181531014677	1067	29949			
SGTC_2611	pyromycin	23.93	µM	-1.95392361248064	0.0160587127373779	no	3263	0.0253551258172756	1064	196990	An antibiotic that causes premature chain termination during translation. Part of the molecule resembles the 3' end of the aminoacylated tRNAs. It will enter the A site and transfer to the growing chain, causing premature chain release.		
SGTC_928	2764-0428	58.7	µM	-1.97472310142414	0.0151378487867818	no	3264	0.0241497899165445	1067	662578			
SGTC_1578	josamycin	24.2	µM	-1.97663551258381	0.0150555039625933	no	3265	0.0240414224782307	1062	5282165	A P450 substrate.		
SGTC_2801	7907800	81.82	µM	-1.97668134906829	0.0150535350630106	no	3266	0.0240388301599372	1045	6620925			
SGTC_60	0986-0278	202	µM	-1.98049787145067	0.0148903713155323	no	3267	0.023823806142958	1074	3110598			
SGTC_1208	2323-2347	50.3	µM	-1.98123580991728	0.0148589990582203	no	3268	0.0237824175522777	1058	5412760			
SGTC_1245	0418-0076	17.2	µM	-1.99032252215114	0.0144773274004189	no	3269	0.0232777092839151	1077	6790114			
SGTC_1915	st067105	30.6	µM	-1.99203009274426	0.0144065537244415	no	3270	0.0231838781032843	1055	69751		YOR207C | YOR116C	RET1 | RPO31
SGTC_2253	7938677	135.83	µM	-1.99591479790866	0.0142466532548691	no	3271	0.0229715988477777	1078	2301972			
SGTC_241	5hr heat shock (37°C) + cantharidin	155.449	µM	-1.99657776370549	0.0142195178264894	no	3272	0.0229355352020271	1066	2545	Cantharidin is a toxic blistering agent secreted by the Spanish fly of unknown mechanism. In Saccharomyces cerevisiae, cantharidin is thought to act by inhibiting GLC7 (encoding  type 1 serine/threonine protein phosphatase) as decreased expression confers hypersensitivity and overexpression confers resisitance (Hoon et al., Nat Chem Biol 4, 2008).	YER133W	GLC7
SGTC_1141	3253-0389	52.6	µM	-2.00418650872942	0.01391126332587	no	3273	0.0225250426079772	1064	5402031			
SGTC_750	4073-0104	132	µM	-2.00656595994347	0.0138160544636867	no	3274	0.0223979494408766	1000	22330957			
SGTC_453	enantio-paf c16	10	µM	-2.00732737822811	0.0137857068010701	no	3275	0.0223574079088091	1051	13871343	A lipid and platelet activating factor		
SGTC_1092	toremifene	6.32	µM	-2.01028180814852	0.0136684965619125	no	3276	0.0222006855828844	1073	3005573	A first generation selective estrogen receptor modulator (SERM). Like tamoxifen, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.		
SGTC_1723	st034307	2.5525	µM	-2.01226740998164	0.0135902063706879	no	3277	0.0220958779577483	1055	867466			
SGTC_904	1141-0088	396	µM	-2.01462764559269	0.0134976484579279	no	3278	0.0219718392804936	1076	1378119			
SGTC_1294	1000-1494	117	µM	-2.02057864524934	0.0132666890915234	no	3279	0.0216617006893804	1071	712797		YDL207W	GLE1
SGTC_2577	2',4'-dihydroxy-4-methoxychalcone	15.32	µM	-2.02345356677736	0.013156341248151	no	3280	0.021513203115262	1056	5711223	A potent inhibitor of glutathione S-transferases.		
SGTC_1526	st051518	75	µM	-2.02433445699556	0.0131226892545829	no	3281	0.021467875289962	1052	673993			
SGTC_2247	cerulenin	830	nM	-2.02914807647784	0.0129401090539192	no	3282	0.0212216051761409	1053	5282054	Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis.	YHR107C	CDC12
SGTC_983	1491-0821	12.2	µM	-2.03156392850733	0.0128493067261369	no	3283	0.0210989107665872	1065	46495113			
SGTC_974	1326-0144	138	µM	-2.04231008777042	0.0124520480884704	no	3284	0.0205603910426813	1068	5411856			
SGTC_426	0988-0037	14.6	µM	-2.04472103961809	0.0123643963818246	no	3285	0.0204411840742978	1068	5383008			
SGTC_1765	st044815	90.4	µM	-2.0492616985934	0.0122007681849189	no	3286	0.0202182658930252	1061	645695			
SGTC_2442	5158906	48.48	µM	-2.05049734055413	0.0121565664564609	no	3287	0.0201579615232486	1064	1893835			
SGTC_930	2810-3379	265	µM	-2.06779502239541	0.0115522093055155	no	3288	0.0193296509805151	1068	1015764			
SGTC_530	4358-1714	28	µM	-2.06836869338641	0.0115326211912105	no	3289	0.0193026833771061	1050	1564641			
SGTC_2279	7948423	32.93	µM	-2.07402490995169	0.0113410277105433	no	3290	0.0190384987370153	1061	1247112			
SGTC_929	2805-0021	398	µM	-2.07615109867441	0.01126972575803	no	3291	0.0189399892064435	1075	3098024			
SGTC_1504	k297-0033	30	µM	-2.08059646696699	0.0111219078490614	no	3292	0.0187354287812473	1045	4388117			
SGTC_2936	9038235	15.59	µM	-2.08594443384054	0.0109463133375046	no	3293	0.018491828349952	1052	4749415			
SGTC_1112	tnp00069	1.16933	µM	-2.08884900947963	0.0108519594823435	no	3294	0.0183606585470425	1067	145826			
SGTC_214	4373-3496	70	µM	-2.09068827763927	0.010792578399936	no	3295	0.01827800824475	1072	3779166			
SGTC_1362	1611-0397	101	µM	-2.10414992074859	0.0103665145095891	no	3296	0.0176826856928068	1073	27816			
SGTC_703	3875-0075	71.8	µM	-2.10890870410181	0.0102194455969014	no	3297	0.0174762313774543	1087	2850814			
SGTC_579	4491-1009	110	µM	-2.11386752629714	0.010068133955594	no	3298	0.0172632917568582	1075	1271041			
SGTC_1068	loratadine	26.9	µM	-2.11512251624352	0.0100301510761058	no	3299	0.0172097533148665	1077	3957	A H1 histamine antagonist.		
SGTC_531	3788-1495	174	µM	-2.11973069502879	0.00989175295297091	no	3300	0.0170143814319242	1065	2896655			
SGTC_1919	st067113	52.3	µM	-2.12083601847128	0.00985880561443748	no	3301	0.0169678022282913	1059	1268243			
SGTC_269	exalamide	29	µM	-2.12258320489729	0.0098069211684427	no	3302	0.0168943967851176	1079	3316	A derivative of salicylamide.		
SGTC_3206	9114350	49.47	µM	-2.12997560981449	0.00959002667706906	no	3303	0.0165868135251626	1054	17087243			
SGTC_3030	9087619	49.47	µM	-2.13477303178663	0.00945152343237666	no	3304	0.0163897770805348	1061	25236973			
SGTC_2689	tacrolimus	100	µM	-2.13957198251018	0.00931472938152229	no	3305	0.0161946864346624	1031	23581796	Tacrolimus, also known as FK-506, is a potent immunosuppressant, neuroprotective and neuroregenerative, and T cell proliferation blocker. FK-506 disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12).		
SGTC_506	n9-isopropylolomoucine	153	µM	-2.16822195239175	0.00853354930315398	no	3306	0.0150709016697381	1076	6610355			
SGTC_2686	alizarin	95.37	µM	-2.17532464618866	0.0083490127274171	no	3307	0.0148028984360534	1067	6293	Alizarin, an anthraquinone, binds to and calcium and forms precipitates; used as a biological stain to quantify free calcium.	YHR062C	RPP1
SGTC_2599	2',3-dihydroxy-4,4',6'-trimethoxychalcone	100	µM	-2.19504524713177	0.00785489408278412	no	3308	0.0140801760942069	1053	5379071			
SGTC_2051	5263410	176	µM	-2.20206456535304	0.00768533056923507	no	3309	0.0138303740272789	1070	227584			
SGTC_2929	9013348	24.6	µM	-2.20494674541628	0.00761664510133027	no	3310	0.0137289158702185	1064	2995952			
SGTC_69	0096-0274	206.684	µM	-2.21524007535734	0.0073757359818094	no	3311	0.0133717952629685	1068	6741392			
SGTC_1238	0333-0287	48.8	µM	-2.22566327016017	0.00713865586235688	no	3312	0.0130183723779492	1067	7226			
SGTC_1459	k035-0031	35.7	µM	-2.23763670469837	0.00687463346256432	no	3313	0.0126223779677576	1053	3877128		YMR208W	ERG12
SGTC_2433	5607874	27.82	µM	-2.24370908736029	0.00674405857887741	no	3314	0.0124255625215402	1061	2252428			
SGTC_384	k007-0144	5.16	µM	-2.27995362459399	0.00600931128822004	no	3315	0.0113052195546736	1077	6824886			
SGTC_2402	5553605	200	µM	-2.29126828982603	0.00579494913658491	no	3316	0.010973950716382	1081	6758546			
SGTC_356	1634-0012	32.5	µM	-2.29814726461393	0.00566796515483108	no	3317	0.0107767044773884	1072	735457			
SGTC_3031	9088762	49.47	µM	-2.30568567462406	0.00553165074235639	no	3318	0.0105641010698338	1077	205253			
SGTC_2197	6588183	93.1375	µM	-2.31801132588049	0.00531503714755233	no	3319	0.010224352765518	1081	884136			
SGTC_1787	fluconazole	80	µM	-2.32401693407514	0.00521225257577052	no	3320	0.0100622932293836	1056	3365	Fluconazole is a triazole antifungal; inhibits lanosterol 14α-demethylase preventing the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.	YOL135C | YOR232W | YCL017C | YOL134C	MED7 | MGE1 | NFS1 | YOL134C
SGTC_1716	st033144	30.6155	µM	-2.3358877631042	0.00501427521190272	no	3321	0.00974854594855005	1079	674617			
SGTC_469	w7	172	µM	-2.33961598354038	0.00495349439289917	no	3322	0.00965178839070957	1085	45115570	A P450 inhibitor.		
SGTC_295	k015-0027	31	µM	-2.34743772346298	0.00482810601300672	no	3323	0.00945151644598944	1082	3887424			
SGTC_355	1311-2252	105	µM	-2.36504220466175	0.0045561887549405	no	3324	0.00901400816985245	1082	5338538			
SGTC_326	k292-0812	17.5	µM	-2.3702249771131	0.00447878413213432	no	3325	0.00888863211930046	1071	3579357			
SGTC_3234	9132280	49.47	µM	-2.42187177941536	0.0037692710712241	no	3326	0.00772039879630259	1081	17612295			
SGTC_35	0133-0054	64.071	µM	-2.42854708371416	0.00368533608872046	no	3327	0.00757972830605384	1068	99677			
SGTC_912	3474-0017	2.18	µM	-2.45405498490906	0.00337983138511843	no	3328	0.00706276903646017	1082	3360550			
SGTC_479	n-linoleoylglycine	10	µM	-2.45734802976409	0.00334209681188179	no	3329	0.00699835080457823	1086	6433346	An anti-infammatory.		
SGTC_537	1334-0398	209	µM	-2.46534473028478	0.00325203543757387	no	3330	0.00684407433596168	1082	5846986			
SGTC_1025	k007-0731	70	µM	-2.46942720515423	0.00320690424298866	no	3331	0.00676647747984528	1082	6256118			
SGTC_290	2043-6722	48.1	µM	-2.48892674539482	0.00299901887303969	no	3332	0.00640646815754034	1085	773758		YLR208W	SEC13
SGTC_1018	4259-0013	28.1	µM	-2.51212316741708	0.0027675844521048	no	3333	0.00600035979903208	1076	6801262			
SGTC_282	k297-0036	65.7	µM	-2.53392507517053	0.00256488735048843	no	3334	0.00563964229039162	1079	5061378			
SGTC_1781	st038725	66.3	µM	-2.54566129666975	0.00246141958117536	no	3335	0.00545354804756966	1086	4270275		YIL048W	NEO1
SGTC_2416	tofa	880	nM	-2.58402677087725	0.00214899198228505	no	3336	0.00488271070523653	1078	115175	TOFA (5-(Tetradecyloxy)-2-furoic acid) is a cell-permeable, potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in fatty acid biosynthesis. Inhibits cellular fatty acid synthesis in a dose-dependent manner		
SGTC_1798	st045719	60.953	µM	-2.59539130393223	0.00206360928721753	no	3337	0.0047241641339012	1079	3980186			
SGTC_3209	9113616	49.47	µM	-2.60419454369112	0.00199959858799596	no	3338	0.00460452338106663	1079	16649353			
SGTC_2058	5236698	133	µM	-2.63411473244219	0.00179528769702191	no	3339	0.00421784887891834	1083	766665			
SGTC_1782	st039423	80.636	µM	-2.64672623387828	0.0017150073363671	no	3340	0.00406375602520497	1092	2068169			
SGTC_251	melphalan	456.522	µM	-2.65071152689692	0.0016903263311826	no	3341	0.0040161206475566	1094	460612	A DNA alkylator.		
SGTC_2450	5739737	12.93	µM	-2.68921225569362	0.0014680168906747	no	3342	0.00358104316659336	1078	2262825			
SGTC_547	1120-0019	610	nM	-2.68989322469666	0.00146433695721912	no	3343	0.00357374421000831	1050	3676939			
SGTC_729	4092-0585	94.1	µM	-2.79657518641918	0.000981562276899448	yes	3344	0.00258236961993059	1087	2169061			
SGTC_2569	tetrandrine	100	µM	-2.80243612748375	0.000959849728365675	yes	3345	0.00253591291732908	1081	73078	Tetrandrine a bis-benzylisoquinoline alkaloid, a calcium channel blocker.		
SGTC_1145	3546-0597	10.2	µM	-2.8174767399501	0.000906132616228664	yes	3346	0.00242013102255344	1095	875334			
SGTC_2238	6671620	73.2395	µM	-2.83397163924065	0.000850407632988607	yes	3347	0.00229867059280498	1078	729941			
SGTC_604	1000-0114	314	µM	-2.83971885624552	0.000831744332448608	yes	3348	0.00225766548235972	1093	1572745			
SGTC_3294	9122953	26.2835	µM	-2.98391828500374	0.000470514076490797	yes	3349	0.00142291381205483	1089	16459826			
SGTC_1307	1187-1599	12.2	µM	-2.98588148917066	0.000466798576076625	yes	3350	0.0014138110101705	1094	1538471			
SGTC_2117	5521686	200	µM	-3.01202971075493	0.000419835170783645	yes	3351	0.00129753598481797	1093	803312			
SGTC_2426	5582046	32.21	µM	-3.06470182985648	0.000338246295183715	yes	3352	0.00108943551767047	1091	2251934			
SGTC_511	blebbistatin	171	µM	-3.08229980601274	0.000314453157213599	yes	3353	0.00102703921653798	1091	3476986	A myosin inhibitor.		
SGTC_2434	5670830	169.91	µM	-3.14809802987712	0.000238606350743098	yes	3354	0.00082168285789192	1085	1549830			
SGTC_489	paxilline	115	µM	-3.60762206306952	2.99978513311984e-05	yes	3355	0.000154508086148593	1094	105008	A toxic potassium channel blocker.		
SGTC_2621	lithochol-11-enic acid	100	µM	-4.65605319440699	1.00550392795966e-07	yes	3356	1.61164343383868e-06	1094	6708711