Protein of unknown function; expressed at both mRNA and protein levels
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YNL184C deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Correlation | pval | ORF | Gene | Zygosity | Description |
---|---|---|---|---|---|
0.546 | 2.23E-260 | YJL023C | PET130 | hom | Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
0.539 | 1.75E-252 | YDR462W | MRPL28 | hom | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress |
0.519 | 1.93E-231 | YPR166C | MRP2 | hom | Mitochondrial ribosomal protein of the small subunit |
0.510 | 1.52E-220 | YMR287C | DSS1 | hom | 3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs |
0.506 | 1.70E-217 | YDR237W | MRPL7 | hom | Mitochondrial ribosomal protein of the large subunit; MRPL7 produces both YmL5 and YmL7, which are two different modified forms of the same protein |
0.505 | 1.29E-216 | YNL252C | MRPL17 | hom | Mitochondrial ribosomal protein of the large subunit |
0.503 | 4.17E-214 | YMR098C | ATP25 | hom | Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA and for the Oli1p ring formation; YMR098C is not an essential gene |
0.498 | 5.48E-210 | YGR215W | RSM27 | hom | Mitochondrial ribosomal protein of the small subunit |
0.498 | 1.42E-209 | YDR518W | EUG1 | hom | Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER |
0.492 | 5.19E-204 | YGR220C | MRPL9 | hom | Mitochondrial ribosomal protein of the large subunit |
0.491 | 1.04E-202 | YGR102C | GTF1 | hom | Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; transposon insertion mutant is salt sensitive and null mutant has growth defects; non-tagged protein is detected in purified mitochondria |
0.483 | 9.71E-196 | YOR330C | MIP1 | hom | Mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; mutations in the human ortholog POLG are associated with Alpers-Huttenlocher syndrome (AHS) and other mitochondrial diseases; Mip1p is the single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoans in which there is a complex of a catalytic subunit and an accessory subunit |
0.479 | 5.27E-192 | YNL177C | MRPL22 | hom | Mitochondrial ribosomal protein of the large subunit |
0.478 | 5.99E-191 | YGL064C | MRH4 | hom | Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function |
0.473 | 1.78E-186 | YCR071C | IMG2 | hom | Mitochondrial ribosomal protein of the large subunit |