| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|
| 0.139 |
6.28E-16 |
YDL233W_p |
MFG1_p |
hom |
Regulator of filamentous growth; interacts with FLO11 promoter and regulates FLO11 expression; binds to transcription factors Flo8p and Mss11p; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YDL233W is not an essential gene |
| 0.114 |
4.21E-11 |
YBL029W_p |
YBL029W_p |
hom |
Non-essential protein of unknown function |
| 0.106 |
6.49E-10 |
YGL261C_p |
PAU11_p |
hom |
Putative protein of unknown function and member of the seripauperin multigene family encoded mainly in subtelomeric regions; mRNA expression appears to be regulated by SUT1 and UPC2 |
| 0.099 |
7.91E-9 |
YOR080W |
DIA2 |
hom |
Origin-binding F-box protein; forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication; plays a role in transcription; required for correct assembly of RSC complex, correct RSC-mediated transcription regulation, and correct nucleosome positioning; involved in invasive and pseudohyphal growth; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase |
| 0.095 |
3.03E-8 |
YFL019C_d |
YFL019C_d |
hom |
Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene |
| 0.094 |
4.98E-8 |
YJR110W |
YMR1 |
hom |
Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family |
| 0.090 |
2.04E-7 |
YGR051C_d |
YGR051C_d |
hom |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene |
| 0.088 |
2.87E-7 |
YKL113C |
RAD27 |
hom |
5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family |
| 0.083 |
1.42E-6 |
YLR045C |
STU2 |
het |
Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p |
| 0.081 |
2.93E-6 |
YJR036C |
HUL4 |
hom |
Protein with similarity to hect domain E3 ubiquitin-protein ligases; not essential for viability; found in association with Trf4 in TRAMP complex |
| 0.076 |
1.16E-5 |
YML010W |
SPT5 |
het |
Component of the universally conserved Spt4/5 complex (DSIF complex); the complex has multiple roles in concert with RNA polymerases I and II, including regulation of transcription elongation, RNA processing, quality control, and transcription-coupled DNA repair |
| 0.076 |
1.17E-5 |
YPR027C_p |
YPR027C_p |
hom |
Putative protein of unknown function |
| 0.073 |
2.28E-5 |
YCR023C |
YCR023C |
hom |
Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene |
| 0.073 |
2.55E-5 |
YIR018W |
YAP5 |
hom |
Basic leucine zipper (bZIP) iron-sensing transcription factor; YAP5 has a paralog, YAP7, that arose from the whole genome duplication |
| 0.072 |
2.74E-5 |
YPR032W |
SRO7 |
hom |
Effector of Rab GTPase Sec4p; forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Drosophila lgl tumor suppressor; SRO7 has a paralog, SRO77, that arose from the whole genome duplication |
