YOR084W / LPX1

Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction

Zygosity: Homozygous strain
fixedexpanded
Profile for YOR084W / LPX1

Click on Significant Values for Screen Details ID:SGTC_37|Compound:0566-0070|FD-Score:-3.50|P-value:2.61E-5 ID:SGTC_38|Compound:0929-0051|FD-Score:4.66|P-value:3.32E-8 ID:SGTC_40|Compound:0327-0103|FD-Score:-2.96|P-value:3.19E-4 ID:SGTC_46|Compound:0329-0187a|FD-Score:3.27|P-value:7.46E-5 ID:SGTC_77|Compound:0828-0286|FD-Score:-3.14|P-value:1.43E-4 ID:SGTC_78|Compound:0336-0123|FD-Score:-2.72|P-value:8.36E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:2.75|P-value:6.96E-4 ID:SGTC_360|Compound:0957-0399|FD-Score:3.21|P-value:9.87E-5 ID:SGTC_415|Compound:dibenzyl ketone|FD-Score:2.94|P-value:3.19E-4 ID:SGTC_448|Compound:monastrol|FD-Score:-2.86|P-value:4.85E-4 ID:SGTC_719|Compound:2810-4230|FD-Score:-2.79|P-value:6.41E-4 ID:SGTC_737|Compound:1950-0117|FD-Score:3.14|P-value:1.32E-4 ID:SGTC_753|Compound:1322-0200|FD-Score:2.73|P-value:7.55E-4 ID:SGTC_822|Compound:1487-0950|FD-Score:3.55|P-value:1.89E-5 ID:SGTC_828|Compound:2074-0507|FD-Score:3.15|P-value:1.27E-4 ID:SGTC_882|Compound:0843-0131|FD-Score:2.67|P-value:9.51E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:3.43|P-value:3.40E-5 ID:SGTC_1007|Compound:4101-0031|FD-Score:2.89|P-value:3.89E-4 ID:SGTC_1128|Compound:3448-9350|FD-Score:2.70|P-value:8.50E-4 ID:SGTC_1187|Compound:1391-0724|FD-Score:-2.99|P-value:2.76E-4 ID:SGTC_1202|Compound:1988-0068|FD-Score:2.78|P-value:6.35E-4 ID:SGTC_1203|Compound:3992-3522|FD-Score:3.26|P-value:7.72E-5 ID:SGTC_1677|Compound:st019204|FD-Score:2.68|P-value:9.21E-4 ID:SGTC_1915|Compound:st067105|FD-Score:-2.98|P-value:2.89E-4 ID:SGTC_2031|Compound:5180455|FD-Score:-2.74|P-value:7.88E-4 ID:SGTC_2071|Compound:5230951|FD-Score:-3.13|P-value:1.53E-4 ID:SGTC_2096|Compound:5468907|FD-Score:5.18|P-value:9.28E-10 ID:SGTC_2101|Compound:5377231|FD-Score:2.72|P-value:7.81E-4 ID:SGTC_2103|Compound:5378138|FD-Score:2.96|P-value:3.00E-4 ID:SGTC_2126|Compound:5251174|FD-Score:2.84|P-value:4.87E-4 ID:SGTC_2792|Compound:7535235|FD-Score:-3.16|P-value:1.32E-4 ID:SGTC_2794|Compound:7785382|FD-Score:4.72|P-value:2.27E-8 ID:SGTC_2795|Compound:7780010|FD-Score:-5.37|P-value:2.65E-10 ID:SGTC_37|Compound:0566-0070|FD-Score:-3.50|P-value:2.61E-5 ID:SGTC_38|Compound:0929-0051|FD-Score:4.66|P-value:3.32E-8 ID:SGTC_40|Compound:0327-0103|FD-Score:-2.96|P-value:3.19E-4 ID:SGTC_46|Compound:0329-0187a|FD-Score:3.27|P-value:7.46E-5 ID:SGTC_77|Compound:0828-0286|FD-Score:-3.14|P-value:1.43E-4 ID:SGTC_78|Compound:0336-0123|FD-Score:-2.72|P-value:8.36E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:2.75|P-value:6.96E-4 ID:SGTC_360|Compound:0957-0399|FD-Score:3.21|P-value:9.87E-5 ID:SGTC_415|Compound:dibenzyl ketone|FD-Score:2.94|P-value:3.19E-4 ID:SGTC_448|Compound:monastrol|FD-Score:-2.86|P-value:4.85E-4 ID:SGTC_719|Compound:2810-4230|FD-Score:-2.79|P-value:6.41E-4 ID:SGTC_737|Compound:1950-0117|FD-Score:3.14|P-value:1.32E-4 ID:SGTC_753|Compound:1322-0200|FD-Score:2.73|P-value:7.55E-4 ID:SGTC_822|Compound:1487-0950|FD-Score:3.55|P-value:1.89E-5 ID:SGTC_828|Compound:2074-0507|FD-Score:3.15|P-value:1.27E-4 ID:SGTC_882|Compound:0843-0131|FD-Score:2.67|P-value:9.51E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:3.43|P-value:3.40E-5 ID:SGTC_1007|Compound:4101-0031|FD-Score:2.89|P-value:3.89E-4 ID:SGTC_1128|Compound:3448-9350|FD-Score:2.70|P-value:8.50E-4 ID:SGTC_1187|Compound:1391-0724|FD-Score:-2.99|P-value:2.76E-4 ID:SGTC_1202|Compound:1988-0068|FD-Score:2.78|P-value:6.35E-4 ID:SGTC_1203|Compound:3992-3522|FD-Score:3.26|P-value:7.72E-5 ID:SGTC_1677|Compound:st019204|FD-Score:2.68|P-value:9.21E-4 ID:SGTC_1915|Compound:st067105|FD-Score:-2.98|P-value:2.89E-4 ID:SGTC_2031|Compound:5180455|FD-Score:-2.74|P-value:7.88E-4 ID:SGTC_2071|Compound:5230951|FD-Score:-3.13|P-value:1.53E-4 ID:SGTC_2096|Compound:5468907|FD-Score:5.18|P-value:9.28E-10 ID:SGTC_2101|Compound:5377231|FD-Score:2.72|P-value:7.81E-4 ID:SGTC_2103|Compound:5378138|FD-Score:2.96|P-value:3.00E-4 ID:SGTC_2126|Compound:5251174|FD-Score:2.84|P-value:4.87E-4 ID:SGTC_2792|Compound:7535235|FD-Score:-3.16|P-value:1.32E-4 ID:SGTC_2794|Compound:7785382|FD-Score:4.72|P-value:2.27E-8 ID:SGTC_2795|Compound:7780010|FD-Score:-5.37|P-value:2.65E-10

Top fitness defect scores for YOR084W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2096 5468907 5.18 200.0 µM 9.28E-10 2 1.09E-7
2 SGTC_2794 7785382 4.72 27.3 µM 2.27E-8 12 1.21E-6
3 SGTC_38 0929-0051 4.66 58.3 µM 3.32E-8 11 1.60E-6
4 SGTC_822 1487-0950 3.55 154.0 µM 1.89E-5 24 1.92E-4
5 SGTC_1004 4084-0029 3.43 199.0 µM 3.40E-5 34 2.99E-4
6 SGTC_46 0329-0187a 3.27 2.2 µM 7.46E-5 107 5.43E-4
7 SGTC_1203 3992-3522 3.26 103.0 µM 7.72E-5 67 5.57E-4
8 SGTC_360 0957-0399 3.21 1.0 µM 9.87E-5 cell wall 79 6.71E-4
9 SGTC_828 2074-0507 3.15 139.0 µM 1.27E-4 RPP1 & pyrimidine depletion 55 8.13E-4
10 SGTC_737 1950-0117 3.14 57.9