Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.615 |
0 |
YNL252C |
MRPL17 |
hom |
Mitochondrial ribosomal protein of the large subunit |
0.612 |
0 |
YDR518W |
EUG1 |
hom |
Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER |
0.600 |
0 |
YJL023C |
PET130 |
hom |
Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
0.579 |
4.52E-299 |
YOR330C |
MIP1 |
hom |
Mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; mutations in the human ortholog POLG are associated with Alpers-Huttenlocher syndrome (AHS) and other mitochondrial diseases; Mip1p is the single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoans in which there is a complex of a catalytic subunit and an accessory subunit |
0.570 |
5.22E-288 |
YDR462W |
MRPL28 |
hom |
Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress |
0.569 |
1.87E-287 |
YGR220C |
MRPL9 |
hom |
Mitochondrial ribosomal protein of the large subunit |
0.566 |
6.34E-284 |
YCR024C |
SLM5 |
hom |
Mitochondrial asparaginyl-tRNA synthetase |
0.555 |
3.20E-270 |
YDR237W |
MRPL7 |
hom |
Mitochondrial ribosomal protein of the large subunit; MRPL7 produces both YmL5 and YmL7, which are two different modified forms of the same protein |
0.544 |
3.72E-258 |
YDR533C |
HSP31 |
hom |
Possible chaperone and cysteine protease; has similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress |
0.528 |
1.59E-240 |
YOR158W |
PET123 |
hom |
Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator |
0.521 |
1.62E-232 |
YKL068W-A_p |
YKL068W-A_p |
hom |
Putative protein of unknown function; identified by homology to Ashbya gossypii |
0.519 |
1.93E-231 |
YNL184C_p |
YNL184C_p |
hom |
Protein of unknown function; expressed at both mRNA and protein levels |
0.519 |
5.19E-231 |
YNL213C |
RRG9 |
hom |
Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
0.518 |
8.44E-230 |
YGL064C |
MRH4 |
hom |
Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function |
0.512 |
1.45E-223 |
YDR079W |
PET100 |
hom |
Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme |