Deletion Strain | FD score | P-value | Gene | Gene Description |
---|
YNL226W_d | 6.42 | 7.01E-11 | YNL226W_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene JJJ1/YNL227C |
YOR277C_d | 5.93 | 1.53E-9 | YOR277C_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene CAF20 |
YBR027C_d | 5.76 | 4.12E-9 | YBR027C_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
YLR177W_p | 4.71 | 1.22E-6 | YLR177W_p | Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; not an essential gene; YLR177W has a paralog, PSP1, that arose from the whole genome duplication |
YIL162W | 4.65 | 1.65E-6 | SUC2 | Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
YJR142W_p | 4.50 | 3.34E-6 | YJR142W_p | Putative protein of unknown function; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition; nudix hydrolase family member |
YPR101W | 4.45 | 4.29E-6 | SNT309 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; interacts physically and genetically with Prp19p |
YLR037C | 4.27 | 9.85E-6 | PAU23 | Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expressed under anaerobic conditions, completely repressed during aerobic growth |
YKR093W | 3.94 | 4.01E-5 | PTR2 | Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p |
YNL323W | 3.91 | 4.68E-5 | LEM3 | Membrane protein of the plasma membrane and ER, interacts specifically in vivo with the phospholipid translocase (flippase) Dnf1p; involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane |
YLL006W | 3.89 | 4.95E-5 | MMM1 | ER integral membrane protein, component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth |
YMR159C | 3.85 | 5.93E-5 | ATG16 | Conserved protein involved in autophagy; interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which localize to the pre-autophagosomal structure and are required for autophagy; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress |
YOL037C_d | 3.82 | 6.57E-5 | YOL037C_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOL036W |
YNL097C-B_p | 3.80 | 7.20E-5 | YNL097C-B_p | Putative protein of unknown function |
YAR020C | 3.67 | 1.19E-4 | PAU7 | Member of the seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme |