Deletion Strain | FD score | P-value | Gene | Gene Description |
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YDL159W-A_p | 8.42 | 1.83E-17 | YDL159W-A_p | Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species |
YOL033W | 6.21 | 2.71E-10 | MSE1 | Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated |
YOL092W_p | 4.89 | 4.96E-7 | YPQ1_p | Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; member of the PQ-loop family, with seven transmembrane domains; similar to mammalian PQLC2 vacuolar transporter |
YDL170W | 4.82 | 7.34E-7 | UGA3 | Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus |
YDL136W | 4.78 | 8.72E-7 | RPL35B | Ribosomal 60S subunit protein L35B; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35B has a paralog, RPL35A, that arose from the whole genome duplication |
YHR134W | 4.71 | 1.23E-6 | WSS1 | Sumoylated protein that localizes to a single spot on the nuclear periphery of mother cells but not daughters; interacts genetically with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response |
YIR037W | 4.67 | 1.50E-6 | HYR1 | Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor |
YBR156C | 4.53 | 2.97E-6 | SLI15 | Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly |
YDR482C | 4.43 | 4.72E-6 | CWC21 | Protein involved in RNA splicing by the spliceosome; component of a complex containing Cef1p; interacts genetically with ISY1 and BUD13; may bind RNA; has similarity to S. pombe Cwf21p |
YBR133C | 4.30 | 8.72E-6 | HSL7 | Protein arginine N-methyltransferase; exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p; relocalizes away from bud neck upon DNA replication stress |
YDR011W | 4.26 | 1.02E-5 | SNQ2 | Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species |
YOR222W | 4.14 | 1.73E-5 | ODC2 | Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism |
YNL202W | 4.13 | 1.81E-5 | SPS19 | Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate |
YDR337W | 4.01 | 3.03E-5 | MRPS28 | Mitochondrial ribosomal protein of the small subunit |
YPL257W_p | 3.87 | 5.45E-5 | YPL257W_p | Putative protein of unknown function; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene |