N-acetylfarnesylcysteine

(2R)-2-acetamido-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid

Potential activator of peroxisome proliferator-activated receptor ╬│ (PPAR╬│).

[PubChem] [DrugBank] [Wikipedia] [WikiGenes] [ChEMBL] [ChemSpider] 

PubChem MeSH terms: Enzyme Inhibitors



Source SMILES: standardizedunstandardized
Compound:
Screen ID SGTC_461
Screen concentration 136.0 μM
Source ICCB bioactive library
PubChem CID 6438381
SMILES CC(=CCCC(=CCCC(=CCSCC(C(=O)O)NC(=O)C)C)C)C
Standardized SMILES CC(=CCCC(=CCCC(=CCSCC(NC(=O)C)C(=O)O)C)C)C
Molecular weight 367.5459
ALogP 4.72
H-bond donor count 2
H-bond acceptor count 4
Response signature

Pool Growth Kinetics
% growth inhibition (Het. pool) 3.74
% growth inhibition (Hom. pool) 3.06


HIP profile

Heterozygous deletion strains
Scale: fixedexpanded
Heterozygous profile for 6438381
Download HIP data (tab-delimited text)  (excel)
Gene:RDS3(YPR094W)|FD-Score:3.29|P-value:4.99E-4|Clearance:0.52||SGD DESC:Component of the SF3b subcomplex of the U2 snRNP, zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance Gene:RET1(YOR207C)|FD-Score:-3.93|P-value:4.28E-5|Clearance:0||SGD DESC:Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs Gene:SLD5(YDR489W)|FD-Score:3.29|P-value:4.99E-4|Clearance:0.52||SGD DESC:Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery Gene:SPN1(YPR133C)|FD-Score:3.36|P-value:3.90E-4|Clearance:0.52||SGD DESC:Protein involved in RNA polymerase II transcription; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype Gene:RDS3(YPR094W)|FD-Score:3.29|P-value:4.99E-4|Clearance:0.52||SGD DESC:Component of the SF3b subcomplex of the U2 snRNP, zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance Gene:RET1(YOR207C)|FD-Score:-3.93|P-value:4.28E-5|Clearance:0||SGD DESC:Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs Gene:SLD5(YDR489W)|FD-Score:3.29|P-value:4.99E-4|Clearance:0.52||SGD DESC:Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery Gene:SPN1(YPR133C)|FD-Score:3.36|P-value:3.90E-4|Clearance:0.52||SGD DESC:Protein involved in RNA polymerase II transcription; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype

HOP profile

Homozygous deletion strains
Scale: fixedexpanded
Homozygous profile for 6438381
Download HOP data (tab-delimited text)  (excel)
Gene:ACN9(YDR511W)|FD-Score:-3.23|P-value:6.20E-4||SGD DESC:Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes Gene:ADE17(YMR120C)|FD-Score:-4.26|P-value:1.03E-5||SGD DESC:Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine Gene:ADE6(YGR061C)|FD-Score:-3.11|P-value:9.51E-4||SGD DESC:Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway Gene:BPT1(YLL015W)|FD-Score:-3.23|P-value:6.16E-4||SGD DESC:ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p Gene:DOG2(YHR043C)|FD-Score:3.41|P-value:3.23E-4||SGD DESC:2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, paralogous to DOG1, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed Gene:MET10(YFR030W)|FD-Score:3.87|P-value:5.47E-5||SGD DESC:Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide Gene:MHF1(YOL086W-A)|FD-Score:-5.42|P-value:2.91E-8||SGD DESC:Component of the heterotetrameric MHF histone-fold complex; in humans the MMF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1 Gene:MRPS12(YNR036C)|FD-Score:3.09|P-value:9.95E-4||SGD DESC:Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins Gene:MSC7(YHR039C)|FD-Score:3.32|P-value:4.46E-4||SGD DESC:Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids Gene:SHE9(YDR393W)|FD-Score:-3.45|P-value:2.76E-4||SGD DESC:Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex Gene:SNA3(YJL151C)|FD-Score:3.79|P-value:7.61E-5||SGD DESC:Protein involved in efficient MVB sorting of proteins to the vacuole; may function as an RSP5 adapter protein for MVB cargos; integral membrane protein localized to vacuolar intralumenal vesicles Gene:STD1(YOR047C)|FD-Score:3.18|P-value:7.29E-4||SGD DESC:Protein involved in control of glucose-regulated gene expression; interacts with kinase Snf1p, glucose sensors Snf3p and Rgt2p, TATA-binding Spt15p; regulator of transcription factor Rgt1p; interactions with Pma1p appear to propagate [GAR+] Gene:TRM7(YBR061C)|FD-Score:3.11|P-value:9.36E-4||SGD DESC:2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively Gene:YBL065W(YBL065W_d)|FD-Score:-3.26|P-value:5.55E-4||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene Gene:YDR278C(YDR278C_d)|FD-Score:3.74|P-value:9.06E-5||SGD DESC:Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data Gene:YER175W-A(YER175W-A_p)|FD-Score:-3.12|P-value:8.99E-4||SGD DESC:Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching Gene:YLR415C(YLR415C_p)|FD-Score:-3.2|P-value:6.83E-4||SGD DESC:Putative protein of unknown function; YLR415C is not an essential gene Gene:YMR252C(YMR252C_p)|FD-Score:3.16|P-value:7.84E-4||SGD DESC:Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YMR252C is not an essential gene Gene:YNL276C(YNL276C_d)|FD-Score:4.83|P-value:6.84E-7||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene MET2/YNL277W Gene:YOR152C(YOR152C_p)|FD-Score:-3.4|P-value:3.34E-4||SGD DESC:Putative protein of unknown function; YOR152C is not an essential gene Gene:YPL035C(YPL035C_d)|FD-Score:3.86|P-value:5.74E-5||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene Gene:ACN9(YDR511W)|FD-Score:-3.23|P-value:6.20E-4||SGD DESC:Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes Gene:ADE17(YMR120C)|FD-Score:-4.26|P-value:1.03E-5||SGD DESC:Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine Gene:ADE6(YGR061C)|FD-Score:-3.11|P-value:9.51E-4||SGD DESC:Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway Gene:BPT1(YLL015W)|FD-Score:-3.23|P-value:6.16E-4||SGD DESC:ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p Gene:DOG2(YHR043C)|FD-Score:3.41|P-value:3.23E-4||SGD DESC:2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, paralogous to DOG1, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed Gene:MET10(YFR030W)|FD-Score:3.87|P-value:5.47E-5||SGD DESC:Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide Gene:MHF1(YOL086W-A)|FD-Score:-5.42|P-value:2.91E-8||SGD DESC:Component of the heterotetrameric MHF histone-fold complex; in humans the MMF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1 Gene:MRPS12(YNR036C)|FD-Score:3.09|P-value:9.95E-4||SGD DESC:Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins Gene:MSC7(YHR039C)|FD-Score:3.32|P-value:4.46E-4||SGD DESC:Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids Gene:SHE9(YDR393W)|FD-Score:-3.45|P-value:2.76E-4||SGD DESC:Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex Gene:SNA3(YJL151C)|FD-Score:3.79|P-value:7.61E-5||SGD DESC:Protein involved in efficient MVB sorting of proteins to the vacuole; may function as an RSP5 adapter protein for MVB cargos; integral membrane protein localized to vacuolar intralumenal vesicles Gene:STD1(YOR047C)|FD-Score:3.18|P-value:7.29E-4||SGD DESC:Protein involved in control of glucose-regulated gene expression; interacts with kinase Snf1p, glucose sensors Snf3p and Rgt2p, TATA-binding Spt15p; regulator of transcription factor Rgt1p; interactions with Pma1p appear to propagate [GAR+] Gene:TRM7(YBR061C)|FD-Score:3.11|P-value:9.36E-4||SGD DESC:2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively Gene:YBL065W(YBL065W_d)|FD-Score:-3.26|P-value:5.55E-4||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene Gene:YDR278C(YDR278C_d)|FD-Score:3.74|P-value:9.06E-5||SGD DESC:Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data Gene:YER175W-A(YER175W-A_p)|FD-Score:-3.12|P-value:8.99E-4||SGD DESC:Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching Gene:YLR415C(YLR415C_p)|FD-Score:-3.2|P-value:6.83E-4||SGD DESC:Putative protein of unknown function; YLR415C is not an essential gene Gene:YMR252C(YMR252C_p)|FD-Score:3.16|P-value:7.84E-4||SGD DESC:Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YMR252C is not an essential gene Gene:YNL276C(YNL276C_d)|FD-Score:4.83|P-value:6.84E-7||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene MET2/YNL277W Gene:YOR152C(YOR152C_p)|FD-Score:-3.4|P-value:3.34E-4||SGD DESC:Putative protein of unknown function; YOR152C is not an essential gene Gene:YPL035C(YPL035C_d)|FD-Score:3.86|P-value:5.74E-5||SGD DESC:Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene

Click on Significant Values for Strain Details

Top 15 HET fitness defect scores (HIP)

Download all HIP Data (tab-delimited text)  (excel)
Deletion Strain FD score P-value Clearance Gene Gene Description
YPR133C3.363.90E-40.52SPN1Protein involved in RNA polymerase II transcription; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype
YDR489W3.294.99E-40.52SLD5Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
YPR094W3.294.99E-40.52RDS3Component of the SF3b subcomplex of the U2 snRNP, zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance
YDL103C2.770.002770.04QRI1UDP-N-acetylglucosamine pyrophosphorylase; catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis; protein abundance increases in response to DNA replication stress
YLR010C2.730.003130.24TEN1Protein that regulates telomeric length; protects telomeric ends in a complex with Cdc13p and Stn1p
YJR076C2.490.006360.01CDC11Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells
YEL032W2.480.006480.03MCM3Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YJL041W2.450.007050.12NSP1FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p); forms foci at the nuclear periphery upon DNA replication stress
YFL038C2.330.009790.13YPT1Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
YFR004W2.210.013700.00RPN11Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes; protein abundance increases in response to DNA replication stress
YFL005W2.200.013900.08SEC4Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
YGL130W2.120.017000.03CEG1Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphosphatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide
YML015C2.090.018500.01TAF11TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors
YCL031C2.070.019100.01RRP7Essential protein involved in rRNA processing and ribosome biogenesis; protein abundance increases in response to DNA replication stress
YMR043W2.060.019600.02MCM1Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes

Top 15 HOM fitness defect scores (HOP)

Download all HOP Data (tab-delimited text)  (excel)
Deletion Strain FD score P-value Gene Gene Description
YNL276C_d4.836.84E-7YNL276C_dDubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene MET2/YNL277W
YFR030W3.875.47E-5MET10Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide
YPL035C_d3.865.74E-5YPL035C_dDubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene
YJL151C3.797.61E-5SNA3Protein involved in efficient MVB sorting of proteins to the vacuole; may function as an RSP5 adapter protein for MVB cargos; integral membrane protein localized to vacuolar intralumenal vesicles
YDR278C_d3.749.06E-5YDR278C_dDubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHR043C3.413.23E-4DOG22-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, paralogous to DOG1, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
YHR039C3.324.46E-4MSC7Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids
YOR047C3.187.29E-4STD1Protein involved in control of glucose-regulated gene expression; interacts with kinase Snf1p, glucose sensors Snf3p and Rgt2p, TATA-binding Spt15p; regulator of transcription factor Rgt1p; interactions with Pma1p appear to propagate [GAR+]
YMR252C_p3.167.84E-4YMR252C_pPutative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YMR252C is not an essential gene
YBR061C3.119.36E-4TRM72'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively
YNR036C3.099.95E-4MRPS12Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins
YML090W_d3.000.00136YML090W_dDubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source
YAL064C-A_p3.000.00137TDA8_pPutative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene
YGR049W2.940.00162SCM4Mitochondrial outer membrane protein of unknown function; predicted to have 4 transmembrane segments; import is mediated by Tom70p and Mim1p; interacts genetically with a cdc4 mutation
YBL070C_d2.870.00206YBL070C_dDubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data

GO enrichment analysis for SGTC_461
No biological processes are significantly enriched (FDR < 0.1).

No protein complexes are significantly enriched (FDR < 0.1).

Coinhibitory screens
Download Coinhibition data (tab-delimited text)  (excel)

Correlation pval Screen ID Condition Source PubChem
CID
Tanimoto
Score
Response
Signature
0.2851.54E-110SGTC_460trequinsin 123.0 μMMiscellaneous55370.0238095
0.1303.65E-23SGTC_448monastrol 171.0 μMICCB bioactive library29879270.0779221
0.0595.21E-6SGTC_447ml7 120.0 μMICCB bioactive library42160.0135135NEO1-PIK1
0.0596.82E-6SGTC_3021094-0063 18.9 μMChemDiv (Drug-like library)54402890.0769231
0.0518.47E-5SGTC_499genistein 192.0 μMICCB bioactive library66103450.0144928
0.0518.49E-5SGTC_1732st034308 51.8 μMTimTec (Natural product derivative library)8301190.0298507
0.0491.78E-4SGTC_23985228213 48.8 μMMiscellaneous807710.0163934iron homeostasis
0.0491.85E-4SGTC_597k018-0003 82.8 μMChemDiv (Drug-like library)67862340.032967RNA pol III & RNase P/MRP
0.0482.57E-4SGTC_9473447-0010 211.0 μMChemDiv (Drug-like library)7483500.057971
0.0472.62E-4SGTC_608k048-0125 159.0 μMChemDiv (Drug-like library)68176520.0933333
0.0472.66E-4SGTC_31849108758 49.5 μMChembridge (Drug-like library)9028850.0909091
0.0473.16E-4SGTC_31299127257 49.5 μMChembridge (Drug-like library)8378940.0895522
0.0473.25E-4SGTC_30999120367 49.5 μMChembridge (Drug-like library)24824940NA
0.0464.14E-4SGTC_24715466956 24.8 μMMiscellaneous7244190.0793651mitochondrial processes
0.0455.28E-4SGTC_27857756463 72.7 μMChembridge (Drug-like library)22015510.0958904

Screens with compounds having similar structures
Screen ID Chemical Concentration Tanimoto Score PubChem ID Source Molecular Weight AlogP H-bond
donor
count
H-bond
acceptor
count
Response
Signature
SGTC_437s-farnesyl-l-cysteine methyl ester6.67 μM0.5306126439225ICCB bioactive library339.535824.92714
SGTC_1588farnesol29.9 μM0.404762445070TimTec (Pure natural product library)222.366344.7611
SGTC_2606farnesol9.78 μM0.404762445070Microsource (Natural product library)222.366344.7611
SGTC_2624nerol100 μM0.380952637566Microsource (Natural product library)154.249322.93411
SGTC_2639lactacystin53 μM0.303033870Miscellaneous376.42526-0.88758
SGTC_1555citronellol128 μM0.258842TimTec (Pure natural product library)156.26523.04911
SGTC_1649st01173751.3 μM0.251761035TimTec (Natural product derivative library)289.455545.21212
SGTC_2546rhodinyl acetate100 μM0.256708682Microsource (Natural product library)198.301883.42802
SGTC_2570licareol100 μM0.22443158Microsource (Natural product library)154.249322.73511
SGTC_409arachidonic acid100 μM0.185185231Miscellaneous304.466886.43912
SGTC_1616st00273456.1 μM0.1851854026101TimTec (Natural product derivative library)356.53997.40224