Deletion Strain | FD score | P-value | Clearance | Gene | Gene Description |
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YOR207C | 15.00 | 6.73E-51 | 6.38 | RET1 | Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs |
YHR062C | 8.58 | 4.81E-18 | 0.47 | RPP1 | Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs |
YBR002C | 8.11 | 2.49E-16 | 2.40 | RER2 | Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting |
YDL152W_d | 5.71 | 5.65E-9 | 0.30 | YDL152W_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SAS10/YDL153C, a component of the small ribosomal subunit processosome |
YDL150W | 5.41 | 3.11E-8 | 0.54 | RPC53 | RNA polymerase III subunit C53 |
YOR224C | 4.87 | 5.63E-7 | 0.50 | RPB8 | RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III |
YGL097W | 4.37 | 6.27E-6 | 0.03 | SRM1 | Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p |
YDR526C_d | 4.34 | 7.25E-6 | 0.44 | YDR526C_d | Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
YPR103W | 3.90 | 4.83E-5 | 0.37 | PRE2 | Beta 5 subunit of the 20S proteasome, responsible for the chymotryptic activity of the proteasome |
YDL193W | 3.53 | 2.11E-4 | 0.13 | NUS1 | Putative prenyltransferase, required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY |
YJL091C | 3.40 | 3.39E-4 | 0.30 | GWT1 | Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors |
YGR082W | 3.09 | 9.88E-4 | 0.07 | TOM20 | Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins |
YLR317W_d | 3.02 | 0.00125 | 0.02 | YLR317W_d | Dubious open reading frame; may be part of a bicistronic transcript with NKP2/YLR315W; overlaps the verified ORF TAD3/YLR316C |
YCR057C | 3.00 | 0.00135 | 0.03 | PWP2 | Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis |
YNL114C_d | 2.97 | 0.00150 | 0.04 | YNL114C_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPC19/YNL113W, an RNA polymerase subunit |