Deletion Strain | FD score | P-value | Gene | Gene Description |
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YPL069C | 6.23 | 2.26E-10 | BTS1 | Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic |
YJR038C_d | 5.92 | 1.64E-9 | YJR038C_d | Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
YNL226W_d | 5.70 | 6.10E-9 | YNL226W_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene JJJ1/YNL227C |
YNL012W | 5.25 | 7.68E-8 | SPO1 | Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation; required to produce bending force necessary for proper prospore membrane assembly during sporulation; has similarity to phospholipase B |
YAR014C | 4.90 | 4.86E-7 | BUD14 | Protein involved in bud-site selection; Bud14p-Glc7p complex is a cortical regulator of dynein; inhibitor of the actin assembly factor Bnr1p (formin); diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; relative distribution to the nucleus increases upon DNA replication stress |
YIL055C_p | 4.82 | 7.17E-7 | YIL055C_p | Putative protein of unknown function |
YOR324C | 4.30 | 8.71E-6 | FRT1 | Tail-anchored ER membrane protein of unknown function; substrate of the phosphatase calcineurin; interacts with homolog Frt2p; promotes cell growth in stress conditions, possibly via a role in posttranslational translocation; FRT1 has a paralog, FRT2, that arose from the whole genome duplication |
YOR036W | 4.09 | 2.12E-5 | PEP12 | Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin |
YDR275W | 3.83 | 6.54E-5 | BSC2 | Protein of unknown function; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; BSC2 has a paralog, IRC23, that arose from the whole genome duplication |
YKL073W | 3.81 | 7.07E-5 | LHS1 | Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway |
YOL028C | 3.78 | 7.76E-5 | YAP7 | Putative basic leucine zipper (bZIP) transcription factor; YAP7 has a paralog, YAP5, that arose from the whole genome duplication |
YOR082C_d | 3.67 | 1.21E-4 | YOR082C_d | Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene YOR083W |
YER105C | 3.64 | 1.37E-4 | NUP157 | Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC assembly and tethering of DNA to the nuclear periphery; both Nup170p and NUP157p are similar to human Nup155p; NUP157 has a paralog, NUP170, that arose from the whole genome duplication |
YLR211C_p | 3.62 | 1.50E-4 | YLR211C_p | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR211C is not an essential gene; ORF contains an intron |
YPL173W | 3.59 | 1.65E-4 | MRPL40 | Mitochondrial ribosomal protein of the large subunit |