| Deletion Strain | FD score | P-value | Gene | Gene Description |
|---|
| YGR093W_p | 6.50 | 4.11E-11 | YGR093W_p | Putative protein of unconfirmed function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus |
| YMR124W_p | 5.25 | 7.74E-8 | YMR124W_p | Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene; predicted to have a role in organelle organization |
| YBL001C | 4.51 | 3.30E-6 | ECM15 | Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis |
| YOR123C | 4.48 | 3.65E-6 | LEO1 | Component of the Paf1 complex; which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay |
| YLR338W_d | 4.33 | 7.53E-6 | OPI9_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF VRP1/YLR337C |
| YEL042W | 4.31 | 8.23E-6 | GDA1 | Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate |
| YIR023W | 3.98 | 3.40E-5 | DAL81 | Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism |
| YMR032W | 3.98 | 3.43E-5 | HOF1 | Bud neck-localized, SH3 domain-containing protein required for cytokinesis; is phosphorylated by Dbf2p; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p |
| YGL157W | 3.91 | 4.70E-5 | ARI1 | NADPH-dependent aldehyde reductase, utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily |
| YBL061C | 3.88 | 5.23E-5 | SKT5 | Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication |
| YAL042C-A_d | 3.80 | 7.11E-5 | YAL042C-A_d | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF ERV46/YAL042W; YAL042C-A is a non-essential gene |
| YDR241W_d | 3.80 | 7.13E-5 | BUD26_d | Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 1% of ORF overlaps the verified gene SNU56; diploid mutant displays a weak budding pattern phenotype in a systematic assay |
| YMR216C | 3.80 | 7.15E-5 | SKY1 | SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 |
| YPR001W | 3.79 | 7.46E-5 | CIT3 | Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate |
| YKR065C | 3.67 | 1.21E-4 | PAM17 | Constituent of the TIM23 complex; proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 (Translocase of the Inner mitochondrial Membrane) complex; protein abundance increases in response to DNA replication stress |
