Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.093 |
7.82E-8 |
YAL065C_p |
YAL065C_p |
hom |
Putative protein of unknown function; has homology to FLO1; possible pseudogene |
0.091 |
1.36E-7 |
YKR018C |
YKR018C |
hom |
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress; YKR018C has a paralog, IML2, that arose from the whole genome duplication |
0.087 |
4.26E-7 |
YBL098W |
BNA4 |
hom |
Kynurenine 3-mono oxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease |
0.085 |
7.22E-7 |
YPL150W_p |
YPL150W_p |
hom |
Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study |
0.080 |
3.24E-6 |
YLR219W |
MSC3 |
hom |
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate; protein abundance increases in response to DNA replication stress |
0.080 |
3.35E-6 |
YAL061W_p |
BDH2_p |
hom |
Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3 |
0.079 |
4.70E-6 |
YBR276C |
PPS1 |
hom |
Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle |
0.075 |
1.40E-5 |
YMR284W |
YKU70 |
hom |
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair |
0.074 |
1.65E-5 |
YOL145C |
CTR9 |
hom |
Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cyclin genes; involved in SER3 repression by helping to maintain SRG1 transcription-dependent nucleosome occupancy; contains TPR repeats |
0.073 |
2.42E-5 |
YMR158W |
MRPS8 |
hom |
Mitochondrial ribosomal protein of the small subunit |
0.072 |
3.38E-5 |
YPL210C |
SRP72 |
het |
Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane |
0.070 |
5.58E-5 |
YBR093C |
PHO5 |
hom |
Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2 |
0.069 |
7.11E-5 |
YLR005W |
SSL1 |
het |
Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p |
0.067 |
1.05E-4 |
YGR145W |
ENP2 |
het |
Essential nucleolar protein, required for biogenesis of the small ribosomal subunit; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p |
0.067 |
1.14E-4 |
YDR182W-A_p |
YDR182W-A_p |
hom |
Putative protein of unknown function; identified by fungal homology and RT-PCR |