Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YAL067C deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Correlation | pval | ORF | Gene | Zygosity | Description |
---|---|---|---|---|---|
0.192 | 4.51E-29 | YNL244C | SUI1 | het | Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase |
0.117 | 8.84E-12 | YDL219W | DTD1 | hom | D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes |
0.099 | 9.59E-9 | YER132C | PMD1 | hom | Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions |
0.085 | 8.21E-7 | YJL057C | IKS1 | hom | Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p |
0.083 | 1.34E-6 | YDR060W | MAK21 | het | Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein |
0.083 | 1.44E-6 | YGR195W | SKI6 | het | Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4) |
0.083 | 1.47E-6 | YEL057C_p | YEL057C_p | hom | Protein of unknown function involved in telomere maintenance; target of UME6 regulation |
0.083 | 1.52E-6 | YOL013W-B_d | YOL013W-B_d | hom | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the long terminal repeat (LTR) of a Ty1 element |
0.082 | 2.03E-6 | YHR066W | SSF1 | hom | Constituent of 66S pre-ribosomal particles; required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family; SSF1 has a paralog, SSF2, that arose from the whole genome duplication |
0.082 | 2.11E-6 | YEL007W | MIT1 | hom | Transcriptional regulator of pseudohyphal growth; protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1) and C. albicans Wor1 |
0.080 | 3.91E-6 | YGR154C | GTO1 | hom | Omega-class glutathione transferase; induced under oxidative stress; putative peroxisomal localization |
0.077 | 8.71E-6 | YGL130W | CEG1 | het | Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphosphatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide |
0.076 | 1.16E-5 | YNL228W_d | YNL228W_d | hom | Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF YNL227C/JJJ1 |
0.074 | 1.65E-5 | YOR206W | NOC2 | het | Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors |
0.074 | 1.80E-5 | YOR298W | MUM3 | hom | Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases |