YBL096C_d

Non-essential protein of unknown function

Zygosity: Homozygous strain
fixedexpanded
Profile for YBL096C / YBL096C

Click on Significant Values for Screen Details ID:SGTC_12|Compound:0849-0099|FD-Score:3.11|P-value:3.82E-4 ID:SGTC_23|Compound:0213-0011|FD-Score:4.05|P-value:5.57E-6 ID:SGTC_47|Compound:0149-0135|FD-Score:-4.19|P-value:2.64E-6 ID:SGTC_134|Compound:0269-0018|FD-Score:3.25|P-value:2.14E-4 ID:SGTC_169|Compound:k015-0017|FD-Score:3.09|P-value:4.09E-4 ID:SGTC_271|Compound:rotenone|FD-Score:3.00|P-value:5.66E-4 ID:SGTC_315|Compound:k915-0449|FD-Score:-3.17|P-value:2.86E-4 ID:SGTC_338|Compound:4055-0136|FD-Score:-3.27|P-value:1.90E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:3.21|P-value:2.56E-4 ID:SGTC_658|Compound:3253-0951|FD-Score:3.53|P-value:6.53E-5 ID:SGTC_716|Compound:1683-5115|FD-Score:2.90|P-value:8.47E-4 ID:SGTC_781|Compound:4335-2806|FD-Score:3.36|P-value:1.33E-4 ID:SGTC_935|Compound:2996-0153|FD-Score:4.22|P-value:2.33E-6 ID:SGTC_954|Compound:1189-0853|FD-Score:4.77|P-value:1.15E-7 ID:SGTC_958|Compound:1222-0007|FD-Score:3.05|P-value:4.82E-4 ID:SGTC_1083|Compound:didemethylchlorpromazine sulfoxide|FD-Score:-3.17|P-value:2.89E-4 ID:SGTC_1115|Compound:galangin|FD-Score:3.45|P-value:9.40E-5 ID:SGTC_1120|Compound:ficusin|FD-Score:4.24|P-value:2.11E-6 ID:SGTC_1129|Compound:3453-1384|FD-Score:2.89|P-value:8.60E-4 ID:SGTC_1138|Compound:3761-0006|FD-Score:3.43|P-value:1.01E-4 ID:SGTC_1196|Compound:1588-0294|FD-Score:-3.19|P-value:2.61E-4 ID:SGTC_1199|Compound:1638-0010|FD-Score:4.34|P-value:1.28E-6 ID:SGTC_1487|Compound:3970-0795|FD-Score:4.10|P-value:4.31E-6 ID:SGTC_1824|Compound:st053723|FD-Score:3.29|P-value:1.85E-4 ID:SGTC_1851|Compound:st056236|FD-Score:3.49|P-value:7.89E-5 ID:SGTC_1910|Compound:st062352|FD-Score:-3.14|P-value:3.15E-4 ID:SGTC_1919|Compound:st067113|FD-Score:3.90|P-value:1.19E-5 ID:SGTC_1922|Compound:5578187|FD-Score:3.92|P-value:1.05E-5 ID:SGTC_1978|Compound:st071761|FD-Score:-2.96|P-value:6.47E-4 ID:SGTC_1992|Compound:st073643|FD-Score:-2.98|P-value:5.88E-4 ID:SGTC_2051|Compound:5263410|FD-Score:-3.98|P-value:7.51E-6 ID:SGTC_2195|Compound:6536160|FD-Score:3.06|P-value:4.62E-4 ID:SGTC_2321|Compound:7390090|FD-Score:3.22|P-value:2.38E-4 ID:SGTC_2412|Compound:st077135|FD-Score:4.32|P-value:1.39E-6 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:-3.30|P-value:1.65E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:4.73|P-value:1.47E-7 ID:SGTC_2585|Compound:alliin|FD-Score:3.00|P-value:5.77E-4 ID:SGTC_2597|Compound:laccaic acid a|FD-Score:4.39|P-value:9.57E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:-3.36|P-value:1.27E-4 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:-4.07|P-value:4.87E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:-2.94|P-value:6.97E-4 ID:SGTC_2749|Compound:bexarotene|FD-Score:2.92|P-value:7.70E-4 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:-3.35|P-value:1.36E-4 ID:SGTC_2815|Compound:7968870|FD-Score:3.32|P-value:1.58E-4 ID:SGTC_2838|Compound:9002687|FD-Score:3.26|P-value:2.08E-4 ID:SGTC_2875|Compound:9039966|FD-Score:-3.09|P-value:3.91E-4 ID:SGTC_3136|Compound:9095672|FD-Score:2.99|P-value:6.07E-4 ID:SGTC_3185|Compound:9108267|FD-Score:-3.50|P-value:6.98E-5 ID:SGTC_12|Compound:0849-0099|FD-Score:3.11|P-value:3.82E-4 ID:SGTC_23|Compound:0213-0011|FD-Score:4.05|P-value:5.57E-6 ID:SGTC_47|Compound:0149-0135|FD-Score:-4.19|P-value:2.64E-6 ID:SGTC_134|Compound:0269-0018|FD-Score:3.25|P-value:2.14E-4 ID:SGTC_169|Compound:k015-0017|FD-Score:3.09|P-value:4.09E-4 ID:SGTC_271|Compound:rotenone|FD-Score:3.00|P-value:5.66E-4 ID:SGTC_315|Compound:k915-0449|FD-Score:-3.17|P-value:2.86E-4 ID:SGTC_338|Compound:4055-0136|FD-Score:-3.27|P-value:1.90E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:3.21|P-value:2.56E-4 ID:SGTC_658|Compound:3253-0951|FD-Score:3.53|P-value:6.53E-5 ID:SGTC_716|Compound:1683-5115|FD-Score:2.90|P-value:8.47E-4 ID:SGTC_781|Compound:4335-2806|FD-Score:3.36|P-value:1.33E-4 ID:SGTC_935|Compound:2996-0153|FD-Score:4.22|P-value:2.33E-6 ID:SGTC_954|Compound:1189-0853|FD-Score:4.77|P-value:1.15E-7 ID:SGTC_958|Compound:1222-0007|FD-Score:3.05|P-value:4.82E-4 ID:SGTC_1083|Compound:didemethylchlorpromazine sulfoxide|FD-Score:-3.17|P-value:2.89E-4 ID:SGTC_1115|Compound:galangin|FD-Score:3.45|P-value:9.40E-5 ID:SGTC_1120|Compound:ficusin|FD-Score:4.24|P-value:2.11E-6 ID:SGTC_1129|Compound:3453-1384|FD-Score:2.89|P-value:8.60E-4 ID:SGTC_1138|Compound:3761-0006|FD-Score:3.43|P-value:1.01E-4 ID:SGTC_1196|Compound:1588-0294|FD-Score:-3.19|P-value:2.61E-4 ID:SGTC_1199|Compound:1638-0010|FD-Score:4.34|P-value:1.28E-6 ID:SGTC_1487|Compound:3970-0795|FD-Score:4.10|P-value:4.31E-6 ID:SGTC_1824|Compound:st053723|FD-Score:3.29|P-value:1.85E-4 ID:SGTC_1851|Compound:st056236|FD-Score:3.49|P-value:7.89E-5 ID:SGTC_1910|Compound:st062352|FD-Score:-3.14|P-value:3.15E-4 ID:SGTC_1919|Compound:st067113|FD-Score:3.90|P-value:1.19E-5 ID:SGTC_1922|Compound:5578187|FD-Score:3.92|P-value:1.05E-5 ID:SGTC_1978|Compound:st071761|FD-Score:-2.96|P-value:6.47E-4 ID:SGTC_1992|Compound:st073643|FD-Score:-2.98|P-value:5.88E-4 ID:SGTC_2051|Compound:5263410|FD-Score:-3.98|P-value:7.51E-6 ID:SGTC_2195|Compound:6536160|FD-Score:3.06|P-value:4.62E-4 ID:SGTC_2321|Compound:7390090|FD-Score:3.22|P-value:2.38E-4 ID:SGTC_2412|Compound:st077135|FD-Score:4.32|P-value:1.39E-6 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:-3.30|P-value:1.65E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:4.73|P-value:1.47E-7 ID:SGTC_2585|Compound:alliin|FD-Score:3.00|P-value:5.77E-4 ID:SGTC_2597|Compound:laccaic acid a|FD-Score:4.39|P-value:9.57E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:-3.36|P-value:1.27E-4 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:-4.07|P-value:4.87E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:-2.94|P-value:6.97E-4 ID:SGTC_2749|Compound:bexarotene|FD-Score:2.92|P-value:7.70E-4 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:-3.35|P-value:1.36E-4 ID:SGTC_2815|Compound:7968870|FD-Score:3.32|P-value:1.58E-4 ID:SGTC_2838|Compound:9002687|FD-Score:3.26|P-value:2.08E-4 ID:SGTC_2875|Compound:9039966|FD-Score:-3.09|P-value:3.91E-4 ID:SGTC_3136|Compound:9095672|FD-Score:2.99|P-value:6.07E-4 ID:SGTC_3185|Compound:9108267|FD-Score:-3.50|P-value:6.98E-5

Top fitness defect scores for YBL096C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_954 1189-0853 4.77 2.9 µM 1.15E-7 endomembrane recycling 22 9.14E-7
2 SGTC_2573 2',4'-dihydroxychalcone 4.73 15.0 µM 1.47E-7 26 1.13E-6
3 SGTC_2597 laccaic acid a 4.39 100.0 µM 9.57E-7 26 5.60E-6
4 SGTC_1199 1638-0010 4.34 4.5 µM 1.28E-6 endomembrane recycling 13 7.20E-6
5 SGTC_2412 st077135 4.32 33.4 µM 1.39E-6 15 7.72E-6
6 SGTC_1120 ficusin 4.24 1.8 µM 2.11E-6 17 1.10E-5
7 SGTC_935 2996-0153 4.22 430.0 µM 2.33E-6 PDR1 16 1.20E-5
8 SGTC_1487 3970-0795 4.10 2.8 µM 4.31E-6 DNA intercalators 5 2.03E-5
9 SGTC_23 0213-0011 4.05 40.0 µM 5.57E-6 copper-dependent oxidative stress 23 2.53E-5
10 SGTC_1922 5578187 3.92 25.0 µM 1.05E-5 TRP & mitochondrial translation 34 4.37E-5
11 SGTC_1919 st067113 3.90 52.3 µM 1.19E-5 TSC3-RPN4 30 4.86E-5
12 SGTC_658 3253-0951 3.53 102.0 µM 6.53E-5 calcium & mitochondrial duress 80 2.08E-4
13 SGTC_1851 st056236 3.49 18.9 µM 7.89E-5 26 2.45E-4
14 SGTC_1115 galangin 3.45 695.7 nM 9.40E-5 RPP1 & pyrimidine depletion 27 2.85E-4
15 SGTC_1138 3761-0006 3.43 1.0 µM 1.01E-4 13 3.04E-4
16 SGTC_781 4335-2806 3.36 94.4 µM 1.33E-4 37 3.84E-4
17 SGTC_2815 7968870 3.32 71.4 µM 1.58E-4 53 4.44E-4
18 SGTC_1824 st053723 3.29 68.6 µM 1.85E-4 54 5.09E-4
19 SGTC_2838 9002687 3.26 71.4 µM 2.08E-4 fatty acid desaturase (OLE1) 45 5.63E-4
20 SGTC_134 0269-0018 3.25 6.9 µM 2.14E-4 173 5.78E-4

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.105 9.28E-10 YGL232W TAN1 hom Putative tRNA acetyltransferase; RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA; protein abundance increases in response to DNA replication stress
0.103 2.52E-9 YPR085C ASA1 het Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1
0.102 2.65E-9 YKL120W OAC1 hom Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family
0.097 1.68E-8 YNL159C ASI2 hom Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals
0.094 5.53E-8 YHR189W PTH1 hom One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for respiratory growth on rich medium, but required for respiratory growth on minimal medium
0.093 6.16E-8 YMR162C DNF3 hom Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vesicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase
0.089 2.31E-7 YOR305W RRG7 hom Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene
0.083 1.28E-6 YFR032C-A RPL29 hom Ribosomal 60S subunit protein L29; not essential for translation, but required for proper joining of large and small ribosomal subunits and for normal translation rate; homologous to mammalian ribosomal protein L29, no bacterial homolog
0.082 2.09E-6 YEL060C PRB1 hom Vacuolar proteinase B (yscB); serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p; protein abundance increases in response to DNA replication stress
0.081 2.74E-6 YBR225W_p YBR225W_p hom Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components
0.079 4.84E-6 YKL068W-A_p YKL068W-A_p hom Putative protein of unknown function; identified by homology to Ashbya gossypii
0.079 4.94E-6 YGR161C_p RTS3_p hom Putative component of the protein phosphatase type 2A complex
0.077 8.87E-6 YIL121W QDR2 hom Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; exports copper; has broad substrate specificity and can transport many mono- and divalent cations; transports a variety of drugs and is required for resistance to quinidine, barban, cisplatin, and bleomycin; contributes to potassium homeostasis; expression is regulated by copper
0.076 1.05E-5 YMR143W RPS16A hom Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S16 and bacterial S9; RPS16A has a paralog, RPS16B, that arose from the whole genome duplication
0.075 1.25E-5 YMR140W SIP5 hom Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase; forms cytoplasmic foci upon DNA replication stress