YBR002C / RER2

Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting

Zygosity: Heterozygous strain
fixedexpanded
Profile for YBR002C / RER2

Click on Significant Values for Screen Details ID:SGTC_10|Compound:0279-0212|FD-Score:17.60|P-value:4.00E-41 ID:SGTC_19|Compound:0279-0214|FD-Score:14.70|P-value:2.78E-29 ID:SGTC_28|Compound:pentachloropyridine N-oxide|FD-Score:4.86|P-value:1.66E-4 ID:SGTC_30|Compound:5-(2-thienylidene)-Rhodanine|FD-Score:4.52|P-value:4.42E-4 ID:SGTC_44|Compound:0929-0055|FD-Score:4.33|P-value:7.21E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:10.80|P-value:1.75E-16 ID:SGTC_101|Compound:0490-5701|FD-Score:6.18|P-value:2.05E-6 ID:SGTC_120|Compound:rhodamine 6G|FD-Score:4.51|P-value:4.48E-4 ID:SGTC_131|Compound:0141-0277|FD-Score:9.44|P-value:5.95E-13 ID:SGTC_134|Compound:0269-0018|FD-Score:8.11|P-value:5.81E-10 ID:SGTC_161|Compound:4065-0411|FD-Score:5.78|P-value:8.67E-6 ID:SGTC_168|Compound:3970-0862|FD-Score:5.39|P-value:3.20E-5 ID:SGTC_173|Compound:1273-0061|FD-Score:11.20|P-value:1.06E-17 ID:SGTC_177|Compound:1327-0068|FD-Score:4.58|P-value:3.71E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:5.06|P-value:9.04E-5 ID:SGTC_186|Compound:3455-3465|FD-Score:7.88|P-value:1.73E-9 ID:SGTC_192|Compound:3455-0609|FD-Score:6.02|P-value:3.66E-6 ID:SGTC_195|Compound:4234-0266|FD-Score:6.85|P-value:1.55E-7 ID:SGTC_204|Compound:1543-0184|FD-Score:10.20|P-value:6.79E-15 ID:SGTC_211|Compound:3455-0679|FD-Score:8.11|P-value:5.80E-10 ID:SGTC_226|Compound:1,3-diallylurea|FD-Score:4.69|P-value:2.73E-4 ID:SGTC_236|Compound:1509-0011|FD-Score:4.53|P-value:4.21E-4 ID:SGTC_255|Compound:tunicamycin|FD-Score:6.57|P-value:4.74E-7 ID:SGTC_342|Compound:k048-0088|FD-Score:4.28|P-value:8.26E-4 ID:SGTC_394|Compound:menadione|FD-Score:-4.59|P-value:1.21E-4 ID:SGTC_435|Compound:c-PAF|FD-Score:-3.91|P-value:8.08E-4 ID:SGTC_441|Compound:propafenone|FD-Score:4.29|P-value:8.02E-4 ID:SGTC_444|Compound:curcumin|FD-Score:-6.21|P-value:4.32E-7 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-7.04|P-value:1.36E-8 ID:SGTC_462|Compound:ag-879|FD-Score:6.26|P-value:1.56E-6 ID:SGTC_503|Compound:tyrphostin 8|FD-Score:8.11|P-value:5.67E-10 ID:SGTC_513|Compound:4245-1575|FD-Score:-4.31|P-value:2.71E-4 ID:SGTC_520|Compound:3584-0023|FD-Score:11.70|P-value:3.30E-19 ID:SGTC_523|Compound:1934-0222|FD-Score:5.31|P-value:4.10E-5 ID:SGTC_553|Compound:k007-0256|FD-Score:6.16|P-value:2.25E-6 ID:SGTC_576|Compound:1073-0113|FD-Score:6.40|P-value:8.92E-7 ID:SGTC_596|Compound:1155-0152|FD-Score:6.75|P-value:2.33E-7 ID:SGTC_602|Compound:3130-1533|FD-Score:8.84|P-value:1.45E-11 ID:SGTC_614|Compound:0462-0418|FD-Score:7.95|P-value:1.24E-9 ID:SGTC_673|Compound:1082-0474|FD-Score:7.37|P-value:1.71E-8 ID:SGTC_676|Compound:falcarinol|FD-Score:4.22|P-value:9.80E-4 ID:SGTC_691|Compound:1548-0686|FD-Score:6.53|P-value:5.57E-7 ID:SGTC_721|Compound:1187-1332|FD-Score:4.37|P-value:6.56E-4 ID:SGTC_745|Compound:0469-0705|FD-Score:4.62|P-value:3.26E-4 ID:SGTC_748|Compound:0136-0228|FD-Score:13.30|P-value:2.54E-24 ID:SGTC_767|Compound:0929-0023|FD-Score:13.30|P-value:2.41E-24 ID:SGTC_876|Compound:0720-0963|FD-Score:4.68|P-value:2.76E-4 ID:SGTC_892|Compound:0929-0076|FD-Score:6.19|P-value:2.00E-6 ID:SGTC_949|Compound:1165-0505|FD-Score:4.30|P-value:7.94E-4 ID:SGTC_1043|Compound:0916-0009|FD-Score:4.63|P-value:3.18E-4 ID:SGTC_1048|Compound:3161-0300|FD-Score:4.23|P-value:9.60E-4 ID:SGTC_1052|Compound:3253-3998|FD-Score:5.87|P-value:6.34E-6 ID:SGTC_1063|Compound:disulfiram|FD-Score:4.48|P-value:4.86E-4 ID:SGTC_1188|Compound:1403-0014|FD-Score:7.45|P-value:1.19E-8 ID:SGTC_1246|Compound:0422-0085|FD-Score:5.19|P-value:6.09E-5 ID:SGTC_1260|Compound:0700-1617|FD-Score:5.12|P-value:7.48E-5 ID:SGTC_1284|Compound:0929-0043|FD-Score:5.04|P-value:9.60E-5 ID:SGTC_1318|Compound:1280-3875|FD-Score:6.59|P-value:4.37E-7 ID:SGTC_1319|Compound:1306-0155|FD-Score:5.70|P-value:1.15E-5 ID:SGTC_1328|Compound:1441-0025|FD-Score:6.14|P-value:2.43E-6 ID:SGTC_1330|Compound:1469-0054|FD-Score:-3.84|P-value:9.71E-4 ID:SGTC_1332|Compound:1480-0653|FD-Score:4.62|P-value:3.33E-4 ID:SGTC_1340|Compound:1486-1359|FD-Score:-5.51|P-value:5.92E-6 ID:SGTC_1346|Compound:1488-2224|FD-Score:5.94|P-value:4.96E-6 ID:SGTC_1347|Compound:1493-0251|FD-Score:-5.15|P-value:2.06E-5 ID:SGTC_1356|Compound:1502-0781|FD-Score:5.01|P-value:1.07E-4 ID:SGTC_1371|Compound:2421-0008|FD-Score:8.05|P-value:7.49E-10 ID:SGTC_1373|Compound:2887-0003|FD-Score:5.65|P-value:1.34E-5 ID:SGTC_1374|Compound:2889-5571|FD-Score:4.43|P-value:5.55E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:5.12|P-value:7.54E-5 ID:SGTC_1441|Compound:4106-0040|FD-Score:4.28|P-value:8.25E-4 ID:SGTC_1456|Compound:k015-0012|FD-Score:5.35|P-value:3.63E-5 ID:SGTC_1478|Compound:0453-0656|FD-Score:6.61|P-value:4.04E-7 ID:SGTC_1622|Compound:st003707|FD-Score:4.61|P-value:3.38E-4 ID:SGTC_1627|Compound:st003713|FD-Score:5.43|P-value:2.85E-5 ID:SGTC_1635|Compound:st007035|FD-Score:5.69|P-value:1.18E-5 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:5.67|P-value:1.26E-5 ID:SGTC_1722|Compound:st034304|FD-Score:4.69|P-value:2.70E-4 ID:SGTC_1723|Compound:st034307|FD-Score:7.02|P-value:7.75E-8 ID:SGTC_1742|Compound:st038235|FD-Score:17.20|P-value:1.78E-39 ID:SGTC_1798|Compound:st045719|FD-Score:-4.04|P-value:5.74E-4 ID:SGTC_1881|Compound:5652484|FD-Score:5.34|P-value:3.82E-5 ID:SGTC_1882|Compound:5615643|FD-Score:9.45|P-value:5.39E-13 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:11.00|P-value:5.01E-17 ID:SGTC_1921|Compound:5740136|FD-Score:9.30|P-value:1.25E-12 ID:SGTC_1922|Compound:5578187|FD-Score:7.15|P-value:4.46E-8 ID:SGTC_1959|Compound:st077091|FD-Score:-5.48|P-value:6.52E-6 ID:SGTC_1999|Compound:st074831|FD-Score:-4.46|P-value:1.76E-4 ID:SGTC_2002|Compound:4023503|FD-Score:5.94|P-value:4.91E-6 ID:SGTC_2016|Compound:5121758|FD-Score:8.22|P-value:3.36E-10 ID:SGTC_2021|Compound:4019055|FD-Score:-4.26|P-value:3.16E-4 ID:SGTC_2029|Compound:5175081|FD-Score:5.58|P-value:1.73E-5 ID:SGTC_2064|Compound:5220758|FD-Score:5.03|P-value:9.85E-5 ID:SGTC_2113|Compound:5491891|FD-Score:4.29|P-value:8.03E-4 ID:SGTC_2122|Compound:5258151|FD-Score:5.63|P-value:1.44E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:5.84|P-value:7.03E-6 ID:SGTC_2225|Compound:6654152|FD-Score:11.60|P-value:8.70E-19 ID:SGTC_2231|Compound:micatex|FD-Score:9.23|P-value:1.85E-12 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:5.81|P-value:7.71E-6 ID:SGTC_2233|Compound:sulbentine|FD-Score:9.41|P-value:6.77E-13 ID:SGTC_2250|Compound:alverine citrate|FD-Score:9.14|P-value:3.03E-12 ID:SGTC_2265|Compound:7929201|FD-Score:5.66|P-value:1.28E-5 ID:SGTC_2275|Compound:7947463|FD-Score:-4.01|P-value:6.25E-4 ID:SGTC_2276|Compound:7947513|FD-Score:4.36|P-value:6.71E-4 ID:SGTC_2307|Compound:7538926|FD-Score:5.43|P-value:2.83E-5 ID:SGTC_2322|Compound:7413319|FD-Score:-4.29|P-value:2.87E-4 ID:SGTC_2325|Compound:6158266|FD-Score:5.90|P-value:5.63E-6 ID:SGTC_2326|Compound:6164455|FD-Score:4.65|P-value:3.04E-4 ID:SGTC_2336|Compound:9001819|FD-Score:10.30|P-value:3.33E-15 ID:SGTC_2337|Compound:9009472|FD-Score:5.71|P-value:1.10E-5 ID:SGTC_2344|Compound:7990960|FD-Score:6.73|P-value:2.46E-7 ID:SGTC_2361|Compound:9034121|FD-Score:5.07|P-value:8.78E-5 ID:SGTC_2393|Compound:9031399|FD-Score:5.34|P-value:3.77E-5 ID:SGTC_2408|Compound:sulbentine|FD-Score:8.32|P-value:2.02E-10 ID:SGTC_2430|Compound:5571206|FD-Score:4.35|P-value:6.96E-4 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:6.59|P-value:4.35E-7 ID:SGTC_2472|Compound:5377652|FD-Score:4.52|P-value:4.37E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:6.60|P-value:4.22E-7 ID:SGTC_2513|Compound:baicalein|FD-Score:12.90|P-value:7.75E-23 ID:SGTC_2516|Compound:gossypol|FD-Score:13.10|P-value:1.15E-23 ID:SGTC_2519|Compound:cryptotanshinone|FD-Score:4.73|P-value:2.40E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-7.58|P-value:1.17E-9 ID:SGTC_2586|Compound:curcumin|FD-Score:-3.93|P-value:7.76E-4 ID:SGTC_2598|Compound:perillyl alcohol|FD-Score:6.50|P-value:6.12E-7 ID:SGTC_2611|Compound:pyromycin|FD-Score:4.67|P-value:2.88E-4 ID:SGTC_2612|Compound:dictamnine|FD-Score:-4.15|P-value:4.26E-4 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:5.43|P-value:2.80E-5 ID:SGTC_2664|Compound:lyso-paf C-16|FD-Score:4.90|P-value:1.47E-4 ID:SGTC_2669|Compound:eugenol|FD-Score:4.36|P-value:6.80E-4 ID:SGTC_2709|Compound:st078560|FD-Score:4.99|P-value:1.13E-4 ID:SGTC_2726|Compound:cimetidine|FD-Score:4.63|P-value:3.19E-4 ID:SGTC_2743|Compound:auranofin|FD-Score:8.32|P-value:2.11E-10 ID:SGTC_2759|Compound:disulfiram|FD-Score:7.66|P-value:4.78E-9 ID:SGTC_2823|Compound:7987624|FD-Score:5.27|P-value:4.72E-5 ID:SGTC_2826|Compound:7992541|FD-Score:4.92|P-value:1.37E-4 ID:SGTC_2836|Compound:9010338|FD-Score:-5.14|P-value:2.13E-5 ID:SGTC_2842|Compound:9000675|FD-Score:5.09|P-value:8.26E-5 ID:SGTC_2844|Compound:9010103|FD-Score:8.33|P-value:1.96E-10 ID:SGTC_2858|Compound:9025781|FD-Score:-5.15|P-value:2.07E-5 ID:SGTC_2889|Compound:9059656|FD-Score:6.13|P-value:2.50E-6 ID:SGTC_2964|Compound:9083345|FD-Score:4.30|P-value:7.94E-4 ID:SGTC_2986|Compound:9022445|FD-Score:-4.23|P-value:3.44E-4 ID:SGTC_2993|Compound:9054257|FD-Score:-5.48|P-value:6.52E-6 ID:SGTC_2997|Compound:9067075|FD-Score:-4.09|P-value:5.08E-4 ID:SGTC_3091|Compound:9116372|FD-Score:5.14|P-value:7.17E-5 ID:SGTC_3107|Compound:9121808|FD-Score:4.84|P-value:1.73E-4 ID:SGTC_3142|Compound:9086498|FD-Score:-4.18|P-value:3.94E-4 ID:SGTC_3152|Compound:9099253|FD-Score:4.42|P-value:5.66E-4 ID:SGTC_3243|Compound:9134147|FD-Score:-4.75|P-value:7.37E-5 ID:SGTC_3302|Compound:9125395|FD-Score:-3.96|P-value:7.15E-4 ID:SGTC_3318|Compound:9139014|FD-Score:4.45|P-value:5.31E-4 ID:SGTC_10|Compound:0279-0212|FD-Score:17.60|P-value:4.00E-41 ID:SGTC_19|Compound:0279-0214|FD-Score:14.70|P-value:2.78E-29 ID:SGTC_28|Compound:pentachloropyridine N-oxide|FD-Score:4.86|P-value:1.66E-4 ID:SGTC_30|Compound:5-(2-thienylidene)-Rhodanine|FD-Score:4.52|P-value:4.42E-4 ID:SGTC_44|Compound:0929-0055|FD-Score:4.33|P-value:7.21E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:10.80|P-value:1.75E-16 ID:SGTC_101|Compound:0490-5701|FD-Score:6.18|P-value:2.05E-6 ID:SGTC_120|Compound:rhodamine 6G|FD-Score:4.51|P-value:4.48E-4 ID:SGTC_131|Compound:0141-0277|FD-Score:9.44|P-value:5.95E-13 ID:SGTC_134|Compound:0269-0018|FD-Score:8.11|P-value:5.81E-10 ID:SGTC_161|Compound:4065-0411|FD-Score:5.78|P-value:8.67E-6 ID:SGTC_168|Compound:3970-0862|FD-Score:5.39|P-value:3.20E-5 ID:SGTC_173|Compound:1273-0061|FD-Score:11.20|P-value:1.06E-17 ID:SGTC_177|Compound:1327-0068|FD-Score:4.58|P-value:3.71E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:5.06|P-value:9.04E-5 ID:SGTC_186|Compound:3455-3465|FD-Score:7.88|P-value:1.73E-9 ID:SGTC_192|Compound:3455-0609|FD-Score:6.02|P-value:3.66E-6 ID:SGTC_195|Compound:4234-0266|FD-Score:6.85|P-value:1.55E-7 ID:SGTC_204|Compound:1543-0184|FD-Score:10.20|P-value:6.79E-15 ID:SGTC_211|Compound:3455-0679|FD-Score:8.11|P-value:5.80E-10 ID:SGTC_226|Compound:1,3-diallylurea|FD-Score:4.69|P-value:2.73E-4 ID:SGTC_236|Compound:1509-0011|FD-Score:4.53|P-value:4.21E-4 ID:SGTC_255|Compound:tunicamycin|FD-Score:6.57|P-value:4.74E-7 ID:SGTC_342|Compound:k048-0088|FD-Score:4.28|P-value:8.26E-4 ID:SGTC_394|Compound:menadione|FD-Score:-4.59|P-value:1.21E-4 ID:SGTC_435|Compound:c-PAF|FD-Score:-3.91|P-value:8.08E-4 ID:SGTC_441|Compound:propafenone|FD-Score:4.29|P-value:8.02E-4 ID:SGTC_444|Compound:curcumin|FD-Score:-6.21|P-value:4.32E-7 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-7.04|P-value:1.36E-8 ID:SGTC_462|Compound:ag-879|FD-Score:6.26|P-value:1.56E-6 ID:SGTC_503|Compound:tyrphostin 8|FD-Score:8.11|P-value:5.67E-10 ID:SGTC_513|Compound:4245-1575|FD-Score:-4.31|P-value:2.71E-4 ID:SGTC_520|Compound:3584-0023|FD-Score:11.70|P-value:3.30E-19 ID:SGTC_523|Compound:1934-0222|FD-Score:5.31|P-value:4.10E-5 ID:SGTC_553|Compound:k007-0256|FD-Score:6.16|P-value:2.25E-6 ID:SGTC_576|Compound:1073-0113|FD-Score:6.40|P-value:8.92E-7 ID:SGTC_596|Compound:1155-0152|FD-Score:6.75|P-value:2.33E-7 ID:SGTC_602|Compound:3130-1533|FD-Score:8.84|P-value:1.45E-11 ID:SGTC_614|Compound:0462-0418|FD-Score:7.95|P-value:1.24E-9 ID:SGTC_673|Compound:1082-0474|FD-Score:7.37|P-value:1.71E-8 ID:SGTC_676|Compound:falcarinol|FD-Score:4.22|P-value:9.80E-4 ID:SGTC_691|Compound:1548-0686|FD-Score:6.53|P-value:5.57E-7 ID:SGTC_721|Compound:1187-1332|FD-Score:4.37|P-value:6.56E-4 ID:SGTC_745|Compound:0469-0705|FD-Score:4.62|P-value:3.26E-4 ID:SGTC_748|Compound:0136-0228|FD-Score:13.30|P-value:2.54E-24 ID:SGTC_767|Compound:0929-0023|FD-Score:13.30|P-value:2.41E-24 ID:SGTC_876|Compound:0720-0963|FD-Score:4.68|P-value:2.76E-4 ID:SGTC_892|Compound:0929-0076|FD-Score:6.19|P-value:2.00E-6 ID:SGTC_949|Compound:1165-0505|FD-Score:4.30|P-value:7.94E-4 ID:SGTC_1043|Compound:0916-0009|FD-Score:4.63|P-value:3.18E-4 ID:SGTC_1048|Compound:3161-0300|FD-Score:4.23|P-value:9.60E-4 ID:SGTC_1052|Compound:3253-3998|FD-Score:5.87|P-value:6.34E-6 ID:SGTC_1063|Compound:disulfiram|FD-Score:4.48|P-value:4.86E-4 ID:SGTC_1188|Compound:1403-0014|FD-Score:7.45|P-value:1.19E-8 ID:SGTC_1246|Compound:0422-0085|FD-Score:5.19|P-value:6.09E-5 ID:SGTC_1260|Compound:0700-1617|FD-Score:5.12|P-value:7.48E-5 ID:SGTC_1284|Compound:0929-0043|FD-Score:5.04|P-value:9.60E-5 ID:SGTC_1318|Compound:1280-3875|FD-Score:6.59|P-value:4.37E-7 ID:SGTC_1319|Compound:1306-0155|FD-Score:5.70|P-value:1.15E-5 ID:SGTC_1328|Compound:1441-0025|FD-Score:6.14|P-value:2.43E-6 ID:SGTC_1330|Compound:1469-0054|FD-Score:-3.84|P-value:9.71E-4 ID:SGTC_1332|Compound:1480-0653|FD-Score:4.62|P-value:3.33E-4 ID:SGTC_1340|Compound:1486-1359|FD-Score:-5.51|P-value:5.92E-6 ID:SGTC_1346|Compound:1488-2224|FD-Score:5.94|P-value:4.96E-6 ID:SGTC_1347|Compound:1493-0251|FD-Score:-5.15|P-value:2.06E-5 ID:SGTC_1356|Compound:1502-0781|FD-Score:5.01|P-value:1.07E-4 ID:SGTC_1371|Compound:2421-0008|FD-Score:8.05|P-value:7.49E-10 ID:SGTC_1373|Compound:2887-0003|FD-Score:5.65|P-value:1.34E-5 ID:SGTC_1374|Compound:2889-5571|FD-Score:4.43|P-value:5.55E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:5.12|P-value:7.54E-5 ID:SGTC_1441|Compound:4106-0040|FD-Score:4.28|P-value:8.25E-4 ID:SGTC_1456|Compound:k015-0012|FD-Score:5.35|P-value:3.63E-5 ID:SGTC_1478|Compound:0453-0656|FD-Score:6.61|P-value:4.04E-7 ID:SGTC_1622|Compound:st003707|FD-Score:4.61|P-value:3.38E-4 ID:SGTC_1627|Compound:st003713|FD-Score:5.43|P-value:2.85E-5 ID:SGTC_1635|Compound:st007035|FD-Score:5.69|P-value:1.18E-5 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:5.67|P-value:1.26E-5 ID:SGTC_1722|Compound:st034304|FD-Score:4.69|P-value:2.70E-4 ID:SGTC_1723|Compound:st034307|FD-Score:7.02|P-value:7.75E-8 ID:SGTC_1742|Compound:st038235|FD-Score:17.20|P-value:1.78E-39 ID:SGTC_1798|Compound:st045719|FD-Score:-4.04|P-value:5.74E-4 ID:SGTC_1881|Compound:5652484|FD-Score:5.34|P-value:3.82E-5 ID:SGTC_1882|Compound:5615643|FD-Score:9.45|P-value:5.39E-13 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:11.00|P-value:5.01E-17 ID:SGTC_1921|Compound:5740136|FD-Score:9.30|P-value:1.25E-12 ID:SGTC_1922|Compound:5578187|FD-Score:7.15|P-value:4.46E-8 ID:SGTC_1959|Compound:st077091|FD-Score:-5.48|P-value:6.52E-6 ID:SGTC_1999|Compound:st074831|FD-Score:-4.46|P-value:1.76E-4 ID:SGTC_2002|Compound:4023503|FD-Score:5.94|P-value:4.91E-6 ID:SGTC_2016|Compound:5121758|FD-Score:8.22|P-value:3.36E-10 ID:SGTC_2021|Compound:4019055|FD-Score:-4.26|P-value:3.16E-4 ID:SGTC_2029|Compound:5175081|FD-Score:5.58|P-value:1.73E-5 ID:SGTC_2064|Compound:5220758|FD-Score:5.03|P-value:9.85E-5 ID:SGTC_2113|Compound:5491891|FD-Score:4.29|P-value:8.03E-4 ID:SGTC_2122|Compound:5258151|FD-Score:5.63|P-value:1.44E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:5.84|P-value:7.03E-6 ID:SGTC_2225|Compound:6654152|FD-Score:11.60|P-value:8.70E-19 ID:SGTC_2231|Compound:micatex|FD-Score:9.23|P-value:1.85E-12 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:5.81|P-value:7.71E-6 ID:SGTC_2233|Compound:sulbentine|FD-Score:9.41|P-value:6.77E-13 ID:SGTC_2250|Compound:alverine citrate|FD-Score:9.14|P-value:3.03E-12 ID:SGTC_2265|Compound:7929201|FD-Score:5.66|P-value:1.28E-5 ID:SGTC_2275|Compound:7947463|FD-Score:-4.01|P-value:6.25E-4 ID:SGTC_2276|Compound:7947513|FD-Score:4.36|P-value:6.71E-4 ID:SGTC_2307|Compound:7538926|FD-Score:5.43|P-value:2.83E-5 ID:SGTC_2322|Compound:7413319|FD-Score:-4.29|P-value:2.87E-4 ID:SGTC_2325|Compound:6158266|FD-Score:5.90|P-value:5.63E-6 ID:SGTC_2326|Compound:6164455|FD-Score:4.65|P-value:3.04E-4 ID:SGTC_2336|Compound:9001819|FD-Score:10.30|P-value:3.33E-15 ID:SGTC_2337|Compound:9009472|FD-Score:5.71|P-value:1.10E-5 ID:SGTC_2344|Compound:7990960|FD-Score:6.73|P-value:2.46E-7 ID:SGTC_2361|Compound:9034121|FD-Score:5.07|P-value:8.78E-5 ID:SGTC_2393|Compound:9031399|FD-Score:5.34|P-value:3.77E-5 ID:SGTC_2408|Compound:sulbentine|FD-Score:8.32|P-value:2.02E-10 ID:SGTC_2430|Compound:5571206|FD-Score:4.35|P-value:6.96E-4 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:6.59|P-value:4.35E-7 ID:SGTC_2472|Compound:5377652|FD-Score:4.52|P-value:4.37E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:6.60|P-value:4.22E-7 ID:SGTC_2513|Compound:baicalein|FD-Score:12.90|P-value:7.75E-23 ID:SGTC_2516|Compound:gossypol|FD-Score:13.10|P-value:1.15E-23 ID:SGTC_2519|Compound:cryptotanshinone|FD-Score:4.73|P-value:2.40E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-7.58|P-value:1.17E-9 ID:SGTC_2586|Compound:curcumin|FD-Score:-3.93|P-value:7.76E-4 ID:SGTC_2598|Compound:perillyl alcohol|FD-Score:6.50|P-value:6.12E-7 ID:SGTC_2611|Compound:pyromycin|FD-Score:4.67|P-value:2.88E-4 ID:SGTC_2612|Compound:dictamnine|FD-Score:-4.15|P-value:4.26E-4 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:5.43|P-value:2.80E-5 ID:SGTC_2664|Compound:lyso-paf C-16|FD-Score:4.90|P-value:1.47E-4 ID:SGTC_2669|Compound:eugenol|FD-Score:4.36|P-value:6.80E-4 ID:SGTC_2709|Compound:st078560|FD-Score:4.99|P-value:1.13E-4 ID:SGTC_2726|Compound:cimetidine|FD-Score:4.63|P-value:3.19E-4 ID:SGTC_2743|Compound:auranofin|FD-Score:8.32|P-value:2.11E-10 ID:SGTC_2759|Compound:disulfiram|FD-Score:7.66|P-value:4.78E-9 ID:SGTC_2823|Compound:7987624|FD-Score:5.27|P-value:4.72E-5 ID:SGTC_2826|Compound:7992541|FD-Score:4.92|P-value:1.37E-4 ID:SGTC_2836|Compound:9010338|FD-Score:-5.14|P-value:2.13E-5 ID:SGTC_2842|Compound:9000675|FD-Score:5.09|P-value:8.26E-5 ID:SGTC_2844|Compound:9010103|FD-Score:8.33|P-value:1.96E-10 ID:SGTC_2858|Compound:9025781|FD-Score:-5.15|P-value:2.07E-5 ID:SGTC_2889|Compound:9059656|FD-Score:6.13|P-value:2.50E-6 ID:SGTC_2964|Compound:9083345|FD-Score:4.30|P-value:7.94E-4 ID:SGTC_2986|Compound:9022445|FD-Score:-4.23|P-value:3.44E-4 ID:SGTC_2993|Compound:9054257|FD-Score:-5.48|P-value:6.52E-6 ID:SGTC_2997|Compound:9067075|FD-Score:-4.09|P-value:5.08E-4 ID:SGTC_3091|Compound:9116372|FD-Score:5.14|P-value:7.17E-5 ID:SGTC_3107|Compound:9121808|FD-Score:4.84|P-value:1.73E-4 ID:SGTC_3142|Compound:9086498|FD-Score:-4.18|P-value:3.94E-4 ID:SGTC_3152|Compound:9099253|FD-Score:4.42|P-value:5.66E-4 ID:SGTC_3243|Compound:9134147|FD-Score:-4.75|P-value:7.37E-5 ID:SGTC_3302|Compound:9125395|FD-Score:-3.96|P-value:7.15E-4 ID:SGTC_3318|Compound:9139014|FD-Score:4.45|P-value:5.31E-4

Top fitness defect scores for YBR002C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_10 0279-0212 17.60 42.6 µM 4.00E-41 TRP & mitochondrial translation 1 1.28E-69 7.44
2 SGTC_1742 st038235 17.20 28.9 µM 1.78E-39 mitochondrial stress 1 8.39E-67 9.59
3 SGTC_19 0279-0214 14.70 38.4 µM 2.78E-29 TRP & mitochondrial translation 1 2.18E-49 8.87
4 SGTC_767 0929-0023 13.30 86.0 µM 2.41E-24 TRP & mitochondrial translation 1 6.06E-41 3.93
5 SGTC_748 0136-0228 13.30 77.9 µM 2.54E-24 redox potentiating 3 6.63E-41 5.45
6 SGTC_2516 gossypol 13.10 71.5 µM 1.15E-23 1 8.76E-40 4.07
7 SGTC_2513 baicalein 12.90 25.6 µM 7.75E-23 calcium & mitochondrial duress 1 2.30E-38 6.10
8 SGTC_520 3584-0023 11.70 682.0 µM 3.30E-19 1 3.74E-32 3.97
9 SGTC_2225 6654152 11.60 15.4 µM 8.70E-19 7 1.97E-31 0.37
10 SGTC_173 1273-0061 11.20 2.7 µM 1.06E-17 mitochondrial stress 4 1.43E-29 4.25
11 SGTC_1883 5-benzylidenerhodanine 11.00 20.0 µM 5.01E-17 TRP & mitochondrial translation 1 2.03E-28 3.62
12 SGTC_70 0141-0289 10.80 43.3 µM 1.75E-16 mitochondrial stress 3 1.74E-27 2.37
13 SGTC_2336 9001819 10.30 198.7 µM 3.33E-15 heme biosynthesis & mitochondrial translocase 8 2.69E-25 0.03
14 SGTC_204 1543-0184 10.20 62.4 µM 6.79E-15 TRP & mitochondrial translation 2 9.12E-25 3.79
15 SGTC_1882 5615643 9.45 20.0 µM 5.39E-13 TRP & mitochondrial translation 1 1.64E-21 3.07
16 SGTC_131 0141-0277 9.44 33.9 µM 5.95E-13 1 1.95E-21 2.87
17 SGTC_2233 sulbentine 9.41 40.4 µM 6.77E-13 10 2.43E-21 0.49
18 SGTC_1921 5740136 9.30 50.0 µM 1.25E-12 TRP & mitochondrial translation 1 6.96E-21 1.64
19 SGTC_2231 micatex 9.23 6.8 µM 1.85E-12 1 1.36E-20 4.14
20 SGTC_2250 alverine citrate 9.14 130.0 µM 3.03E-12 10 3.16E-20 0.09

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.370 1.03E-108 YDL193W NUS1 het Putative prenyltransferase, required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY
0.347 1.46E-95 YIL026C IRR1 het Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability
0.321 4.53E-81 YGL064C MRH4 hom Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function
0.309 9.26E-75 YGR102C GTF1 hom Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; transposon insertion mutant is salt sensitive and null mutant has growth defects; non-tagged protein is detected in purified mitochondria
0.306 1.23E-73 YDR237W MRPL7 hom Mitochondrial ribosomal protein of the large subunit; MRPL7 produces both YmL5 and YmL7, which are two different modified forms of the same protein
0.305 2.92E-73 YPR166C MRP2 hom Mitochondrial ribosomal protein of the small subunit
0.293 3.59E-67 YKL068W-A_p YKL068W-A_p hom Putative protein of unknown function; identified by homology to Ashbya gossypii
0.289 1.88E-65 YOL095C HMI1 hom Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD
0.288 6.24E-65 YDR462W MRPL28 hom Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress
0.287 9.67E-65 YDR509W_d YDR509W_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.287 1.66E-64 YDR533C HSP31 hom Possible chaperone and cysteine protease; has similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress
0.285 9.74E-64 YCR024C SLM5 hom Mitochondrial asparaginyl-tRNA synthetase
0.284 2.96E-63 YNL252C MRPL17 hom Mitochondrial ribosomal protein of the large subunit
0.277 4.74E-60 YOR187W TUF1 hom Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans
0.276 1.66E-59 YBR039W ATP3 hom Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis