YBR006W / UGA2

Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm

Zygosity: Homozygous strain
fixedexpanded
Profile for YBR006W / UGA2

Click on Significant Values for Screen Details ID:SGTC_44|Compound:0929-0055|FD-Score:-5.37|P-value:2.01E-9 ID:SGTC_51|Compound:1013-0126|FD-Score:3.60|P-value:1.63E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:3.36|P-value:4.18E-4 ID:SGTC_116|Compound:0155-0182|FD-Score:3.57|P-value:1.82E-4 ID:SGTC_170|Compound:4197-0004|FD-Score:-2.76|P-value:8.92E-4 ID:SGTC_341|Compound:1486-1430|FD-Score:3.46|P-value:2.89E-4 ID:SGTC_344|Compound:k064-0035|FD-Score:4.53|P-value:2.43E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:5.29|P-value:3.68E-8 ID:SGTC_369|Compound:0957-0393|FD-Score:-3.95|P-value:5.87E-6 ID:SGTC_405|Compound:ebelactone b|FD-Score:3.27|P-value:5.97E-4 ID:SGTC_505|Compound:gw-5074|FD-Score:6.09|P-value:2.46E-10 ID:SGTC_515|Compound:4092-1064|FD-Score:4.43|P-value:3.83E-6 ID:SGTC_562|Compound:3772-2733|FD-Score:3.35|P-value:4.28E-4 ID:SGTC_578|Compound:3460-0051|FD-Score:3.99|P-value:3.13E-5 ID:SGTC_679|Compound:0422-0091|FD-Score:4.33|P-value:6.44E-6 ID:SGTC_687|Compound:k029-0044|FD-Score:3.18|P-value:8.05E-4 ID:SGTC_758|Compound:0868-0029|FD-Score:-3.06|P-value:2.92E-4 ID:SGTC_789|Compound:1309-1135|FD-Score:4.59|P-value:1.75E-6 ID:SGTC_797|Compound:k781-0471|FD-Score:3.97|P-value:3.43E-5 ID:SGTC_861|Compound:0443-0273|FD-Score:5.31|P-value:3.32E-8 ID:SGTC_954|Compound:1189-0853|FD-Score:4.48|P-value:3.00E-6 ID:SGTC_961|Compound:1252-1571|FD-Score:7.88|P-value:2.52E-16 ID:SGTC_964|Compound:1287-0107|FD-Score:-4.88|P-value:4.25E-8 ID:SGTC_1010|Compound:4112-3296|FD-Score:7.63|P-value:2.13E-15 ID:SGTC_1023|Compound:4482-3888|FD-Score:8.56|P-value:5.42E-19 ID:SGTC_1031|Compound:k035-0009|FD-Score:3.66|P-value:1.29E-4 ID:SGTC_1040|Compound:k898-0338|FD-Score:3.58|P-value:1.77E-4 ID:SGTC_1041|Compound:0206-0046|FD-Score:3.30|P-value:5.27E-4 ID:SGTC_1074|Compound:carmofur|FD-Score:8.21|P-value:1.38E-17 ID:SGTC_1081|Compound:sertraline|FD-Score:4.21|P-value:1.12E-5 ID:SGTC_1098|Compound:clofazimine|FD-Score:8.41|P-value:2.20E-18 ID:SGTC_1101|Compound:ebselen|FD-Score:4.41|P-value:4.32E-6 ID:SGTC_1107|Compound:amlodipine|FD-Score:3.99|P-value:3.11E-5 ID:SGTC_1127|Compound:asiatic acid|FD-Score:3.56|P-value:1.90E-4 ID:SGTC_1132|Compound:3456-3614|FD-Score:4.04|P-value:2.49E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:4.67|P-value:1.15E-6 ID:SGTC_1161|Compound:k007-0610|FD-Score:3.71|P-value:1.03E-4 ID:SGTC_1238|Compound:0333-0287|FD-Score:3.36|P-value:4.22E-4 ID:SGTC_1277|Compound:0873-0036|FD-Score:4.83|P-value:4.91E-7 ID:SGTC_1281|Compound:0884-0031|FD-Score:3.82|P-value:6.40E-5 ID:SGTC_1322|Compound:1348-1070|FD-Score:4.34|P-value:5.98E-6 ID:SGTC_1343|Compound:1487-0095|FD-Score:4.89|P-value:3.54E-7 ID:SGTC_1372|Compound:2752-0194|FD-Score:3.48|P-value:2.65E-4 ID:SGTC_1392|Compound:3455-1037|FD-Score:6.05|P-value:3.11E-10 ID:SGTC_1402|Compound:3909-7673|FD-Score:5.81|P-value:1.57E-9 ID:SGTC_1492|Compound:4158-0558|FD-Score:3.95|P-value:3.74E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:6.85|P-value:1.10E-12 ID:SGTC_1502|Compound:4534-4282|FD-Score:7.38|P-value:1.70E-14 ID:SGTC_1545|Compound:lovastatin|FD-Score:3.40|P-value:3.65E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:3.81|P-value:6.77E-5 ID:SGTC_1625|Compound:st003711|FD-Score:3.59|P-value:1.70E-4 ID:SGTC_1676|Compound:st018489|FD-Score:3.75|P-value:8.61E-5 ID:SGTC_1678|Compound:st019265|FD-Score:8.53|P-value:6.80E-19 ID:SGTC_1713|Compound:st033146|FD-Score:4.82|P-value:5.28E-7 ID:SGTC_1727|Compound:st034309|FD-Score:3.32|P-value:4.83E-4 ID:SGTC_1767|Compound:st044992|FD-Score:9.59|P-value:1.68E-23 ID:SGTC_1827|Compound:berberine|FD-Score:3.31|P-value:5.01E-4 ID:SGTC_1945|Compound:st075991|FD-Score:3.76|P-value:8.43E-5 ID:SGTC_1954|Compound:st077032|FD-Score:3.40|P-value:3.65E-4 ID:SGTC_2011|Compound:4012611|FD-Score:3.78|P-value:7.88E-5 ID:SGTC_2167|Compound:5876490|FD-Score:-2.87|P-value:5.92E-4 ID:SGTC_2270|Compound:7924575|FD-Score:3.19|P-value:7.98E-4 ID:SGTC_2299|Compound:7976368|FD-Score:4.58|P-value:1.86E-6 ID:SGTC_2302|Compound:7771753|FD-Score:-3.06|P-value:2.88E-4 ID:SGTC_2333|Compound:9017922|FD-Score:5.12|P-value:1.02E-7 ID:SGTC_2337|Compound:9009472|FD-Score:-3.69|P-value:1.99E-5 ID:SGTC_2354|Compound:9060492|FD-Score:3.95|P-value:3.73E-5 ID:SGTC_2381|Compound:9035592|FD-Score:4.24|P-value:1.00E-5 ID:SGTC_2509|Compound:methyl 7-deshydroxypyrogallin-4-carboxylate|FD-Score:4.44|P-value:3.81E-6 ID:SGTC_2605|Compound:digitonin|FD-Score:6.25|P-value:8.45E-11 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:3.30|P-value:5.26E-4 ID:SGTC_2647|Compound:atorvastatin|FD-Score:3.28|P-value:5.57E-4 ID:SGTC_2724|Compound:maprotiline|FD-Score:3.65|P-value:1.34E-4 ID:SGTC_2725|Compound:haloperidol|FD-Score:3.58|P-value:1.78E-4 ID:SGTC_2761|Compound:levamisole|FD-Score:4.19|P-value:1.24E-5 ID:SGTC_2767|Compound:sibutramine|FD-Score:3.16|P-value:8.75E-4 ID:SGTC_2769|Compound:toremifene|FD-Score:4.55|P-value:2.18E-6 ID:SGTC_2774|Compound:tamoxifen|FD-Score:4.93|P-value:2.97E-7 ID:SGTC_2803|Compound:7707263|FD-Score:4.12|P-value:1.71E-5 ID:SGTC_2804|Compound:7954240|FD-Score:-2.89|P-value:5.55E-4 ID:SGTC_2805|Compound:7950783|FD-Score:7.96|P-value:1.20E-16 ID:SGTC_2810|Compound:7959871|FD-Score:-4.80|P-value:6.45E-8 ID:SGTC_2832|Compound:7992762|FD-Score:4.00|P-value:2.96E-5 ID:SGTC_2938|Compound:9059746|FD-Score:4.93|P-value:2.98E-7 ID:SGTC_2947|Compound:9072639|FD-Score:3.22|P-value:7.13E-4 ID:SGTC_2958|Compound:9077254|FD-Score:3.18|P-value:8.31E-4 ID:SGTC_3113|Compound:9123498|FD-Score:4.55|P-value:2.10E-6 ID:SGTC_3177|Compound:9107506|FD-Score:3.54|P-value:2.07E-4 ID:SGTC_3213|Compound:9129884|FD-Score:3.59|P-value:1.72E-4 ID:SGTC_3223|Compound:9129970|FD-Score:3.15|P-value:9.10E-4 ID:SGTC_3263|Compound:9137018|FD-Score:3.15|P-value:9.14E-4 ID:SGTC_3267|Compound:9137951|FD-Score:3.36|P-value:4.26E-4 ID:SGTC_3268|Compound:9137683|FD-Score:-3.05|P-value:3.00E-4 ID:SGTC_3277|Compound:9138724|FD-Score:3.94|P-value:3.80E-5 ID:SGTC_44|Compound:0929-0055|FD-Score:-5.37|P-value:2.01E-9 ID:SGTC_51|Compound:1013-0126|FD-Score:3.60|P-value:1.63E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:3.36|P-value:4.18E-4 ID:SGTC_116|Compound:0155-0182|FD-Score:3.57|P-value:1.82E-4 ID:SGTC_170|Compound:4197-0004|FD-Score:-2.76|P-value:8.92E-4 ID:SGTC_341|Compound:1486-1430|FD-Score:3.46|P-value:2.89E-4 ID:SGTC_344|Compound:k064-0035|FD-Score:4.53|P-value:2.43E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:5.29|P-value:3.68E-8 ID:SGTC_369|Compound:0957-0393|FD-Score:-3.95|P-value:5.87E-6 ID:SGTC_405|Compound:ebelactone b|FD-Score:3.27|P-value:5.97E-4 ID:SGTC_505|Compound:gw-5074|FD-Score:6.09|P-value:2.46E-10 ID:SGTC_515|Compound:4092-1064|FD-Score:4.43|P-value:3.83E-6 ID:SGTC_562|Compound:3772-2733|FD-Score:3.35|P-value:4.28E-4 ID:SGTC_578|Compound:3460-0051|FD-Score:3.99|P-value:3.13E-5 ID:SGTC_679|Compound:0422-0091|FD-Score:4.33|P-value:6.44E-6 ID:SGTC_687|Compound:k029-0044|FD-Score:3.18|P-value:8.05E-4 ID:SGTC_758|Compound:0868-0029|FD-Score:-3.06|P-value:2.92E-4 ID:SGTC_789|Compound:1309-1135|FD-Score:4.59|P-value:1.75E-6 ID:SGTC_797|Compound:k781-0471|FD-Score:3.97|P-value:3.43E-5 ID:SGTC_861|Compound:0443-0273|FD-Score:5.31|P-value:3.32E-8 ID:SGTC_954|Compound:1189-0853|FD-Score:4.48|P-value:3.00E-6 ID:SGTC_961|Compound:1252-1571|FD-Score:7.88|P-value:2.52E-16 ID:SGTC_964|Compound:1287-0107|FD-Score:-4.88|P-value:4.25E-8 ID:SGTC_1010|Compound:4112-3296|FD-Score:7.63|P-value:2.13E-15 ID:SGTC_1023|Compound:4482-3888|FD-Score:8.56|P-value:5.42E-19 ID:SGTC_1031|Compound:k035-0009|FD-Score:3.66|P-value:1.29E-4 ID:SGTC_1040|Compound:k898-0338|FD-Score:3.58|P-value:1.77E-4 ID:SGTC_1041|Compound:0206-0046|FD-Score:3.30|P-value:5.27E-4 ID:SGTC_1074|Compound:carmofur|FD-Score:8.21|P-value:1.38E-17 ID:SGTC_1081|Compound:sertraline|FD-Score:4.21|P-value:1.12E-5 ID:SGTC_1098|Compound:clofazimine|FD-Score:8.41|P-value:2.20E-18 ID:SGTC_1101|Compound:ebselen|FD-Score:4.41|P-value:4.32E-6 ID:SGTC_1107|Compound:amlodipine|FD-Score:3.99|P-value:3.11E-5 ID:SGTC_1127|Compound:asiatic acid|FD-Score:3.56|P-value:1.90E-4 ID:SGTC_1132|Compound:3456-3614|FD-Score:4.04|P-value:2.49E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:4.67|P-value:1.15E-6 ID:SGTC_1161|Compound:k007-0610|FD-Score:3.71|P-value:1.03E-4 ID:SGTC_1238|Compound:0333-0287|FD-Score:3.36|P-value:4.22E-4 ID:SGTC_1277|Compound:0873-0036|FD-Score:4.83|P-value:4.91E-7 ID:SGTC_1281|Compound:0884-0031|FD-Score:3.82|P-value:6.40E-5 ID:SGTC_1322|Compound:1348-1070|FD-Score:4.34|P-value:5.98E-6 ID:SGTC_1343|Compound:1487-0095|FD-Score:4.89|P-value:3.54E-7 ID:SGTC_1372|Compound:2752-0194|FD-Score:3.48|P-value:2.65E-4 ID:SGTC_1392|Compound:3455-1037|FD-Score:6.05|P-value:3.11E-10 ID:SGTC_1402|Compound:3909-7673|FD-Score:5.81|P-value:1.57E-9 ID:SGTC_1492|Compound:4158-0558|FD-Score:3.95|P-value:3.74E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:6.85|P-value:1.10E-12 ID:SGTC_1502|Compound:4534-4282|FD-Score:7.38|P-value:1.70E-14 ID:SGTC_1545|Compound:lovastatin|FD-Score:3.40|P-value:3.65E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:3.81|P-value:6.77E-5 ID:SGTC_1625|Compound:st003711|FD-Score:3.59|P-value:1.70E-4 ID:SGTC_1676|Compound:st018489|FD-Score:3.75|P-value:8.61E-5 ID:SGTC_1678|Compound:st019265|FD-Score:8.53|P-value:6.80E-19 ID:SGTC_1713|Compound:st033146|FD-Score:4.82|P-value:5.28E-7 ID:SGTC_1727|Compound:st034309|FD-Score:3.32|P-value:4.83E-4 ID:SGTC_1767|Compound:st044992|FD-Score:9.59|P-value:1.68E-23 ID:SGTC_1827|Compound:berberine|FD-Score:3.31|P-value:5.01E-4 ID:SGTC_1945|Compound:st075991|FD-Score:3.76|P-value:8.43E-5 ID:SGTC_1954|Compound:st077032|FD-Score:3.40|P-value:3.65E-4 ID:SGTC_2011|Compound:4012611|FD-Score:3.78|P-value:7.88E-5 ID:SGTC_2167|Compound:5876490|FD-Score:-2.87|P-value:5.92E-4 ID:SGTC_2270|Compound:7924575|FD-Score:3.19|P-value:7.98E-4 ID:SGTC_2299|Compound:7976368|FD-Score:4.58|P-value:1.86E-6 ID:SGTC_2302|Compound:7771753|FD-Score:-3.06|P-value:2.88E-4 ID:SGTC_2333|Compound:9017922|FD-Score:5.12|P-value:1.02E-7 ID:SGTC_2337|Compound:9009472|FD-Score:-3.69|P-value:1.99E-5 ID:SGTC_2354|Compound:9060492|FD-Score:3.95|P-value:3.73E-5 ID:SGTC_2381|Compound:9035592|FD-Score:4.24|P-value:1.00E-5 ID:SGTC_2509|Compound:methyl 7-deshydroxypyrogallin-4-carboxylate|FD-Score:4.44|P-value:3.81E-6 ID:SGTC_2605|Compound:digitonin|FD-Score:6.25|P-value:8.45E-11 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:3.30|P-value:5.26E-4 ID:SGTC_2647|Compound:atorvastatin|FD-Score:3.28|P-value:5.57E-4 ID:SGTC_2724|Compound:maprotiline|FD-Score:3.65|P-value:1.34E-4 ID:SGTC_2725|Compound:haloperidol|FD-Score:3.58|P-value:1.78E-4 ID:SGTC_2761|Compound:levamisole|FD-Score:4.19|P-value:1.24E-5 ID:SGTC_2767|Compound:sibutramine|FD-Score:3.16|P-value:8.75E-4 ID:SGTC_2769|Compound:toremifene|FD-Score:4.55|P-value:2.18E-6 ID:SGTC_2774|Compound:tamoxifen|FD-Score:4.93|P-value:2.97E-7 ID:SGTC_2803|Compound:7707263|FD-Score:4.12|P-value:1.71E-5 ID:SGTC_2804|Compound:7954240|FD-Score:-2.89|P-value:5.55E-4 ID:SGTC_2805|Compound:7950783|FD-Score:7.96|P-value:1.20E-16 ID:SGTC_2810|Compound:7959871|FD-Score:-4.80|P-value:6.45E-8 ID:SGTC_2832|Compound:7992762|FD-Score:4.00|P-value:2.96E-5 ID:SGTC_2938|Compound:9059746|FD-Score:4.93|P-value:2.98E-7 ID:SGTC_2947|Compound:9072639|FD-Score:3.22|P-value:7.13E-4 ID:SGTC_2958|Compound:9077254|FD-Score:3.18|P-value:8.31E-4 ID:SGTC_3113|Compound:9123498|FD-Score:4.55|P-value:2.10E-6 ID:SGTC_3177|Compound:9107506|FD-Score:3.54|P-value:2.07E-4 ID:SGTC_3213|Compound:9129884|FD-Score:3.59|P-value:1.72E-4 ID:SGTC_3223|Compound:9129970|FD-Score:3.15|P-value:9.10E-4 ID:SGTC_3263|Compound:9137018|FD-Score:3.15|P-value:9.14E-4 ID:SGTC_3267|Compound:9137951|FD-Score:3.36|P-value:4.26E-4 ID:SGTC_3268|Compound:9137683|FD-Score:-3.05|P-value:3.00E-4 ID:SGTC_3277|Compound:9138724|FD-Score:3.94|P-value:3.80E-5

Top fitness defect scores for YBR006W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1767 st044992 9.59 70.3 µM 1.68E-23 1 4.30E-22
2 SGTC_1023 4482-3888 8.56 16.0 µM 5.42E-19 TSC3-RPN4 2 5.87E-18
3 SGTC_1678 st019265 8.53 80.2 µM 6.80E-19 60S ribosome export 1 7.24E-18
4 SGTC_1098 clofazimine 8.41 15.1 µM 2.20E-18 heme biosynthesis & mitochondrial translocase 1 2.13E-17
5 SGTC_1074 carmofur 8.21 3.8 µM 1.38E-17 exosome 1 1.15E-16
6 SGTC_2805 7950783 7.96 58.4 µM 1.20E-16 1 8.44E-16
7 SGTC_961 1252-1571 7.88 372.0 µM 2.52E-16 3 1.67E-15
8 SGTC_1010 4112-3296 7.63 15.2 µM 2.13E-15 1 1.19E-14
9 SGTC_1502 4534-4282 7.38 27.7 µM 1.70E-14 1 8.07E-14
10 SGTC_1495 4469-0029 6.85 237.0 µM 1.10E-12 38 3.81E-12
11 SGTC_2605 digitonin 6.25 300.0 nM 8.45E-11 2 2.11E-10
12 SGTC_505 gw-5074 6.09 63.9 µM 2.46E-10 25 5.68E-10
13 SGTC_1392 3455-1037 6.05 33.9 µM 3.11E-10 3 7.06E-10
14 SGTC_1402 3909-7673 5.81 35.9 µM 1.57E-9 4 3.18E-9
15 SGTC_861 0443-0273 5.31 110.0 µM 3.32E-8 1 5.43E-8
16 SGTC_354 2783-3500 5.29 4.9 µM 3.68E-8 cell wall 25 5.98E-8
17 SGTC_2333 9017922 5.12 200.0 µM 1.02E-7 11 1.55E-7
18 SGTC_2774 tamoxifen 4.93 10.9 µM 2.97E-7 5 4.21E-7
19 SGTC_2938 9059746 4.93 27.3 µM 2.98E-7 fatty acid desaturase (OLE1) 21 4.21E-7
20 SGTC_1343 1487-0095 4.89 224.0 µM 3.54E-7 2 4.96E-7

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.089 2.61E-7 YNL123W NMA111 hom Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases
0.080 3.30E-6 YDR466W PKH3 hom Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant
0.079 4.28E-6 YDL010W GRX6 hom Cis-golgi localized monothiol glutaredoxin, binds Fe-S cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; GRX6 has a paralog, GRX7, that arose from the whole genome duplication
0.077 7.67E-6 YDR132C YDR132C hom Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication
0.077 8.40E-6 YOR294W RRS1 het Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington's disease model mice
0.070 4.40E-5 YNL206C RTT106 hom Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition
0.070 5.01E-5 YMR316C-B_d YMR316C-B_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.070 5.32E-5 YOL045W PSK2 hom PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication
0.069 6.03E-5 YGR195W SKI6 het Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)
0.068 7.51E-5 YPL239W YAR1 hom Ankyrin-repeat containing, nucleocytoplasmic shuttling chaperone; prevents aggregation of Rps3p in the cytoplasm, associates with free Rps3p in the cytoplasm and delivers it to the 90S in the nucleus; required for 40S ribosomal subunit export, biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock
0.068 7.72E-5 YBL099W ATP1 hom Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
0.068 7.98E-5 YLR440C SEC39 het Component of the Dsl1p tethering complex that interacts with ER SNAREs Sec20p and Use1p; proposed to be involved in protein secretion; localizes to the ER and nuclear envelope
0.066 1.22E-4 YOL078W AVO1 het Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
0.066 1.45E-4 YMR242W-A_p YMR242W-A_p hom Putative protein of unknown function
0.065 1.76E-4 YLR040C_p YLR040C_p hom Protein of unknown function; localizes to the cell wall; predicted to be a GPI-attached protein; upregulated by Mcm1p-Alpha1p transcription factor; partially overlaps the dubious ORF YLR041W; mRNA identified as translated by ribosome profiling data; YLR040C is not essential