YBR134W_d

Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data

Zygosity: Homozygous strain
fixedexpanded
Profile for YBR134W / YBR134W

Click on Significant Values for Screen Details ID:SGTC_8|Compound:0354-0001|FD-Score:3.46|P-value:1.53E-4 ID:SGTC_29|Compound:0299-0004|FD-Score:3.17|P-value:4.77E-4 ID:SGTC_39|Compound:0986-0283|FD-Score:3.00|P-value:8.94E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:6.68|P-value:1.65E-12 ID:SGTC_71|Compound:0417-1750|FD-Score:-3.03|P-value:7.82E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:-3.77|P-value:4.19E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:4.89|P-value:1.68E-7 ID:SGTC_212|Compound:3807-4682|FD-Score:3.13|P-value:5.62E-4 ID:SGTC_213|Compound:1246-0773|FD-Score:3.45|P-value:1.65E-4 ID:SGTC_259|Compound:usnic acid|FD-Score:3.90|P-value:2.38E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:5.35|P-value:1.22E-8 ID:SGTC_362|Compound:0310-0100|FD-Score:3.64|P-value:7.38E-5 ID:SGTC_399|Compound:oxolinic acid|FD-Score:-3.27|P-value:3.26E-4 ID:SGTC_401|Compound:neomycin|FD-Score:3.13|P-value:5.48E-4 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:4.49|P-value:1.47E-6 ID:SGTC_413|Compound:propylparaben|FD-Score:3.64|P-value:7.27E-5 ID:SGTC_418|Compound:lividomycin a|FD-Score:3.50|P-value:1.32E-4 ID:SGTC_512|Compound:prima-1|FD-Score:3.10|P-value:6.15E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:14.50|P-value:3.66E-52 ID:SGTC_530|Compound:4358-1714|FD-Score:3.85|P-value:2.95E-5 ID:SGTC_556|Compound:4058-0063|FD-Score:3.63|P-value:7.76E-5 ID:SGTC_596|Compound:1155-0152|FD-Score:4.52|P-value:1.26E-6 ID:SGTC_598|Compound:3937-0236|FD-Score:3.30|P-value:2.90E-4 ID:SGTC_599|Compound:1935-0052|FD-Score:3.27|P-value:3.22E-4 ID:SGTC_620|Compound:0109-0052|FD-Score:4.44|P-value:1.80E-6 ID:SGTC_673|Compound:1082-0474|FD-Score:3.95|P-value:1.90E-5 ID:SGTC_675|Compound:1309-0189|FD-Score:3.37|P-value:2.22E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:-3.18|P-value:4.48E-4 ID:SGTC_916|Compound:4466-0038|FD-Score:3.23|P-value:3.87E-4 ID:SGTC_945|Compound:3381-0768|FD-Score:3.13|P-value:5.47E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:3.95|P-value:1.90E-5 ID:SGTC_1007|Compound:4101-0031|FD-Score:3.35|P-value:2.37E-4 ID:SGTC_1169|Compound:aniline yellow|FD-Score:3.02|P-value:8.20E-4 ID:SGTC_1188|Compound:1403-0014|FD-Score:4.16|P-value:7.21E-6 ID:SGTC_1192|Compound:1488-0095|FD-Score:3.07|P-value:6.88E-4 ID:SGTC_1201|Compound:1889-3372|FD-Score:3.23|P-value:3.86E-4 ID:SGTC_1207|Compound:2099-0101|FD-Score:3.98|P-value:1.70E-5 ID:SGTC_1238|Compound:0333-0287|FD-Score:3.67|P-value:6.64E-5 ID:SGTC_1243|Compound:0416-0003|FD-Score:4.49|P-value:1.45E-6 ID:SGTC_1250|Compound:0485-0349|FD-Score:3.09|P-value:6.45E-4 ID:SGTC_1378|Compound:2093-0007|FD-Score:4.64|P-value:6.60E-7 ID:SGTC_1380|Compound:2291-0730|FD-Score:-3.98|P-value:1.66E-5 ID:SGTC_1415|Compound:3966-0071|FD-Score:4.48|P-value:1.48E-6 ID:SGTC_1423|Compound:4048-0112|FD-Score:3.24|P-value:3.69E-4 ID:SGTC_1468|Compound:k284-1086|FD-Score:3.48|P-value:1.45E-4 ID:SGTC_1508|Compound:1080-0625|FD-Score:4.71|P-value:4.46E-7 ID:SGTC_1515|Compound:3460-0031|FD-Score:3.01|P-value:8.45E-4 ID:SGTC_1529|Compound:apigenin|FD-Score:3.74|P-value:4.83E-5 ID:SGTC_1576|Compound:erythromycin ethylsuccinate|FD-Score:3.14|P-value:5.25E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:3.06|P-value:7.11E-4 ID:SGTC_1666|Compound:st014829|FD-Score:3.47|P-value:1.49E-4 ID:SGTC_1677|Compound:st019204|FD-Score:4.04|P-value:1.27E-5 ID:SGTC_1689|Compound:st020265|FD-Score:5.22|P-value:2.65E-8 ID:SGTC_1741|Compound:st038134|FD-Score:4.58|P-value:9.18E-7 ID:SGTC_1749|Compound:st037932|FD-Score:5.15|P-value:4.02E-8 ID:SGTC_1792|Compound:st045773|FD-Score:3.18|P-value:4.67E-4 ID:SGTC_1803|Compound:st050068|FD-Score:3.78|P-value:4.09E-5 ID:SGTC_1808|Compound:st050063|FD-Score:4.07|P-value:1.13E-5 ID:SGTC_1820|Compound:st053765|FD-Score:3.81|P-value:3.63E-5 ID:SGTC_1830|Compound:st055982|FD-Score:3.42|P-value:1.79E-4 ID:SGTC_1866|Compound:st057638|FD-Score:3.02|P-value:8.21E-4 ID:SGTC_1898|Compound:st060199|FD-Score:3.48|P-value:1.46E-4 ID:SGTC_2025|Compound:5147754|FD-Score:6.09|P-value:1.12E-10 ID:SGTC_2029|Compound:5175081|FD-Score:-5.69|P-value:1.46E-9 ID:SGTC_2030|Compound:5175110|FD-Score:5.57|P-value:3.25E-9 ID:SGTC_2034|Compound:5197015|FD-Score:3.99|P-value:1.59E-5 ID:SGTC_2039|Compound:Aminomethylbenzodioxan|FD-Score:-5.94|P-value:2.98E-10 ID:SGTC_2040|Compound:5100729|FD-Score:-4.50|P-value:1.36E-6 ID:SGTC_2042|Compound:p-Dimethylaminoacetophenone|FD-Score:5.16|P-value:3.74E-8 ID:SGTC_2043|Compound:5101342|FD-Score:-2.98|P-value:9.46E-4 ID:SGTC_2083|Compound:5306046|FD-Score:4.94|P-value:1.34E-7 ID:SGTC_2160|Compound:5660466|FD-Score:-3.17|P-value:4.72E-4 ID:SGTC_2267|Compound:7931562|FD-Score:-3.21|P-value:4.01E-4 ID:SGTC_2320|Compound:7373003|FD-Score:3.11|P-value:5.92E-4 ID:SGTC_2461|Compound:5755302|FD-Score:3.48|P-value:1.45E-4 ID:SGTC_2553|Compound:4-methylesculetin|FD-Score:3.48|P-value:1.43E-4 ID:SGTC_2576|Compound:guaiol|FD-Score:3.81|P-value:3.59E-5 ID:SGTC_2581|Compound:avocatin a|FD-Score:3.25|P-value:3.50E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:15.60|P-value:6.96E-60 ID:SGTC_2584|Compound:androsterone|FD-Score:18.50|P-value:3.63E-83 ID:SGTC_2585|Compound:alliin|FD-Score:-4.37|P-value:2.59E-6 ID:SGTC_2632|Compound:3-hydroxy-4-(succin-2-yl)-caryolane delta-lactone|FD-Score:-3.31|P-value:2.81E-4 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:-3.86|P-value:2.78E-5 ID:SGTC_2644|Compound:guaiazulene|FD-Score:3.54|P-value:1.13E-4 ID:SGTC_2657|Compound:nystatin|FD-Score:3.10|P-value:6.15E-4 ID:SGTC_2699|Compound:st077704|FD-Score:3.02|P-value:8.34E-4 ID:SGTC_2829|Compound:7992743|FD-Score:3.59|P-value:9.05E-5 ID:SGTC_2880|Compound:9042983|FD-Score:3.57|P-value:9.81E-5 ID:SGTC_2884|Compound:9058502|FD-Score:3.35|P-value:2.44E-4 ID:SGTC_2989|Compound:9073649|FD-Score:5.38|P-value:9.98E-9 ID:SGTC_3141|Compound:9094609|FD-Score:-3.01|P-value:8.54E-4 ID:SGTC_3144|Compound:9087057|FD-Score:3.02|P-value:8.26E-4 ID:SGTC_3340|Compound:9146634|FD-Score:3.23|P-value:3.81E-4 ID:SGTC_8|Compound:0354-0001|FD-Score:3.46|P-value:1.53E-4 ID:SGTC_29|Compound:0299-0004|FD-Score:3.17|P-value:4.77E-4 ID:SGTC_39|Compound:0986-0283|FD-Score:3.00|P-value:8.94E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:6.68|P-value:1.65E-12 ID:SGTC_71|Compound:0417-1750|FD-Score:-3.03|P-value:7.82E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:-3.77|P-value:4.19E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:4.89|P-value:1.68E-7 ID:SGTC_212|Compound:3807-4682|FD-Score:3.13|P-value:5.62E-4 ID:SGTC_213|Compound:1246-0773|FD-Score:3.45|P-value:1.65E-4 ID:SGTC_259|Compound:usnic acid|FD-Score:3.90|P-value:2.38E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:5.35|P-value:1.22E-8 ID:SGTC_362|Compound:0310-0100|FD-Score:3.64|P-value:7.38E-5 ID:SGTC_399|Compound:oxolinic acid|FD-Score:-3.27|P-value:3.26E-4 ID:SGTC_401|Compound:neomycin|FD-Score:3.13|P-value:5.48E-4 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:4.49|P-value:1.47E-6 ID:SGTC_413|Compound:propylparaben|FD-Score:3.64|P-value:7.27E-5 ID:SGTC_418|Compound:lividomycin a|FD-Score:3.50|P-value:1.32E-4 ID:SGTC_512|Compound:prima-1|FD-Score:3.10|P-value:6.15E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:14.50|P-value:3.66E-52 ID:SGTC_530|Compound:4358-1714|FD-Score:3.85|P-value:2.95E-5 ID:SGTC_556|Compound:4058-0063|FD-Score:3.63|P-value:7.76E-5 ID:SGTC_596|Compound:1155-0152|FD-Score:4.52|P-value:1.26E-6 ID:SGTC_598|Compound:3937-0236|FD-Score:3.30|P-value:2.90E-4 ID:SGTC_599|Compound:1935-0052|FD-Score:3.27|P-value:3.22E-4 ID:SGTC_620|Compound:0109-0052|FD-Score:4.44|P-value:1.80E-6 ID:SGTC_673|Compound:1082-0474|FD-Score:3.95|P-value:1.90E-5 ID:SGTC_675|Compound:1309-0189|FD-Score:3.37|P-value:2.22E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:-3.18|P-value:4.48E-4 ID:SGTC_916|Compound:4466-0038|FD-Score:3.23|P-value:3.87E-4 ID:SGTC_945|Compound:3381-0768|FD-Score:3.13|P-value:5.47E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:3.95|P-value:1.90E-5 ID:SGTC_1007|Compound:4101-0031|FD-Score:3.35|P-value:2.37E-4 ID:SGTC_1169|Compound:aniline yellow|FD-Score:3.02|P-value:8.20E-4 ID:SGTC_1188|Compound:1403-0014|FD-Score:4.16|P-value:7.21E-6 ID:SGTC_1192|Compound:1488-0095|FD-Score:3.07|P-value:6.88E-4 ID:SGTC_1201|Compound:1889-3372|FD-Score:3.23|P-value:3.86E-4 ID:SGTC_1207|Compound:2099-0101|FD-Score:3.98|P-value:1.70E-5 ID:SGTC_1238|Compound:0333-0287|FD-Score:3.67|P-value:6.64E-5 ID:SGTC_1243|Compound:0416-0003|FD-Score:4.49|P-value:1.45E-6 ID:SGTC_1250|Compound:0485-0349|FD-Score:3.09|P-value:6.45E-4 ID:SGTC_1378|Compound:2093-0007|FD-Score:4.64|P-value:6.60E-7 ID:SGTC_1380|Compound:2291-0730|FD-Score:-3.98|P-value:1.66E-5 ID:SGTC_1415|Compound:3966-0071|FD-Score:4.48|P-value:1.48E-6 ID:SGTC_1423|Compound:4048-0112|FD-Score:3.24|P-value:3.69E-4 ID:SGTC_1468|Compound:k284-1086|FD-Score:3.48|P-value:1.45E-4 ID:SGTC_1508|Compound:1080-0625|FD-Score:4.71|P-value:4.46E-7 ID:SGTC_1515|Compound:3460-0031|FD-Score:3.01|P-value:8.45E-4 ID:SGTC_1529|Compound:apigenin|FD-Score:3.74|P-value:4.83E-5 ID:SGTC_1576|Compound:erythromycin ethylsuccinate|FD-Score:3.14|P-value:5.25E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:3.06|P-value:7.11E-4 ID:SGTC_1666|Compound:st014829|FD-Score:3.47|P-value:1.49E-4 ID:SGTC_1677|Compound:st019204|FD-Score:4.04|P-value:1.27E-5 ID:SGTC_1689|Compound:st020265|FD-Score:5.22|P-value:2.65E-8 ID:SGTC_1741|Compound:st038134|FD-Score:4.58|P-value:9.18E-7 ID:SGTC_1749|Compound:st037932|FD-Score:5.15|P-value:4.02E-8 ID:SGTC_1792|Compound:st045773|FD-Score:3.18|P-value:4.67E-4 ID:SGTC_1803|Compound:st050068|FD-Score:3.78|P-value:4.09E-5 ID:SGTC_1808|Compound:st050063|FD-Score:4.07|P-value:1.13E-5 ID:SGTC_1820|Compound:st053765|FD-Score:3.81|P-value:3.63E-5 ID:SGTC_1830|Compound:st055982|FD-Score:3.42|P-value:1.79E-4 ID:SGTC_1866|Compound:st057638|FD-Score:3.02|P-value:8.21E-4 ID:SGTC_1898|Compound:st060199|FD-Score:3.48|P-value:1.46E-4 ID:SGTC_2025|Compound:5147754|FD-Score:6.09|P-value:1.12E-10 ID:SGTC_2029|Compound:5175081|FD-Score:-5.69|P-value:1.46E-9 ID:SGTC_2030|Compound:5175110|FD-Score:5.57|P-value:3.25E-9 ID:SGTC_2034|Compound:5197015|FD-Score:3.99|P-value:1.59E-5 ID:SGTC_2039|Compound:Aminomethylbenzodioxan|FD-Score:-5.94|P-value:2.98E-10 ID:SGTC_2040|Compound:5100729|FD-Score:-4.50|P-value:1.36E-6 ID:SGTC_2042|Compound:p-Dimethylaminoacetophenone|FD-Score:5.16|P-value:3.74E-8 ID:SGTC_2043|Compound:5101342|FD-Score:-2.98|P-value:9.46E-4 ID:SGTC_2083|Compound:5306046|FD-Score:4.94|P-value:1.34E-7 ID:SGTC_2160|Compound:5660466|FD-Score:-3.17|P-value:4.72E-4 ID:SGTC_2267|Compound:7931562|FD-Score:-3.21|P-value:4.01E-4 ID:SGTC_2320|Compound:7373003|FD-Score:3.11|P-value:5.92E-4 ID:SGTC_2461|Compound:5755302|FD-Score:3.48|P-value:1.45E-4 ID:SGTC_2553|Compound:4-methylesculetin|FD-Score:3.48|P-value:1.43E-4 ID:SGTC_2576|Compound:guaiol|FD-Score:3.81|P-value:3.59E-5 ID:SGTC_2581|Compound:avocatin a|FD-Score:3.25|P-value:3.50E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:15.60|P-value:6.96E-60 ID:SGTC_2584|Compound:androsterone|FD-Score:18.50|P-value:3.63E-83 ID:SGTC_2585|Compound:alliin|FD-Score:-4.37|P-value:2.59E-6 ID:SGTC_2632|Compound:3-hydroxy-4-(succin-2-yl)-caryolane delta-lactone|FD-Score:-3.31|P-value:2.81E-4 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:-3.86|P-value:2.78E-5 ID:SGTC_2644|Compound:guaiazulene|FD-Score:3.54|P-value:1.13E-4 ID:SGTC_2657|Compound:nystatin|FD-Score:3.10|P-value:6.15E-4 ID:SGTC_2699|Compound:st077704|FD-Score:3.02|P-value:8.34E-4 ID:SGTC_2829|Compound:7992743|FD-Score:3.59|P-value:9.05E-5 ID:SGTC_2880|Compound:9042983|FD-Score:3.57|P-value:9.81E-5 ID:SGTC_2884|Compound:9058502|FD-Score:3.35|P-value:2.44E-4 ID:SGTC_2989|Compound:9073649|FD-Score:5.38|P-value:9.98E-9 ID:SGTC_3141|Compound:9094609|FD-Score:-3.01|P-value:8.54E-4 ID:SGTC_3144|Compound:9087057|FD-Score:3.02|P-value:8.26E-4 ID:SGTC_3340|Compound:9146634|FD-Score:3.23|P-value:3.81E-4

Top fitness defect scores for YBR134W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2584 androsterone 18.50 48.7 µM 3.63E-83 cell wall 2 1.12E-76
2 SGTC_2582 agaric acid 15.60 100.0 µM 6.96E-60 redox potentiating 12 2.96E-55
3 SGTC_514 4466-0038 14.50 2.6 nM 3.66E-52 cell wall 9 3.76E-48
4 SGTC_58 0957-0393 6.68 9.0 µM 1.65E-12 cell wall 176 1.19E-11
5 SGTC_2025 5147754 6.09 141.0 µM 1.12E-10 1 5.80E-10
6 SGTC_2030 5175110 5.57 200.0 µM 3.25E-9 Golgi 8 1.30E-8
7 SGTC_2989 9073649 5.38 71.4 µM 9.98E-9 11 3.64E-8
8 SGTC_304 1310-0298 5.35 97.0 µM 1.22E-8 cell wall 26 4.40E-8
9 SGTC_1689 st020265 5.22 53.5 µM 2.65E-8 5 8.95E-8
10 SGTC_2042 p-Dimethylaminoacetophenone 5.16 200.0 µM 3.74E-8 4 1.23E-7
11 SGTC_1749 st037932 5.15 54.2 µM 4.02E-8 15 1.32E-7
12 SGTC_2083 5306046 4.94 65.9 µM 1.34E-7 8 3.98E-7
13 SGTC_138 0850-0259 4.89 40.9 µM 1.68E-7 cell wall 146 4.93E-7
14 SGTC_1508 1080-0625 4.71 72.9 µM 4.46E-7 8 1.21E-6
15 SGTC_1378 2093-0007 4.64 380.0 nM 6.60E-7 8 1.74E-6
16 SGTC_1741 st038134 4.58 10.2 µM 9.18E-7 18 2.36E-6
17 SGTC_596 1155-0152 4.52 116.0 µM 1.26E-6 TRP & mitochondrial translation 24 3.16E-6
18 SGTC_1243 0416-0003 4.49 5.7 µM 1.45E-6 PDR1 15 3.59E-6
19 SGTC_410 α-linolenic acid 4.49 100.0 µM 1.47E-6 excess fatty acid 24 3.65E-6
20 SGTC_1415 3966-0071 4.48 78.1 µM 1.48E-6 DNA intercalators 5 3.67E-6

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.495 2.49E-207 YOL003C PFA4 hom Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases
0.393 5.44E-124 YNL106C INP52 hom Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain
0.379 5.16E-115 YLL032C YLL032C hom Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene
0.319 3.38E-80 YBL085W BOI1 hom Protein implicated in polar growth; functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain; relocalizes from bud neck to cytoplasm upon DNA replication stress; BOI1 has a paralog, BOI2, that arose from the whole genome duplication
0.313 4.91E-77 YBR020W GAL1 hom Galactokinase; phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p; GAL1 has a paralog, GAL3, that arose from the whole genome duplication
0.296 1.02E-68 YJL099W CHS6 hom Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
0.295 1.51E-68 YML103C NUP188 hom Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC organization and nucleocytoplasmic transport; homologous to human NUP188
0.294 8.82E-68 YJR142W_p YJR142W_p hom Putative protein of unknown function; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition; nudix hydrolase family member
0.292 5.81E-67 YPL115C BEM3 hom Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
0.292 8.40E-67 YLR102C APC9 hom Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
0.285 1.44E-63 YCL005W LDB16 hom Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria
0.284 2.10E-63 YBR023C CHS3 hom Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan
0.279 7.77E-61 YJR054W KCH1 hom Potassium transporter that mediates K+ influx; activates the high-affinity Ca2+ influx system (HACS) during the mating pheromone response; expression is up-regulated in response to alpha factor; localized to sites of polarized growth; similar to Prm6p; member of a fungal-specific gene family; potential Cdc28p substrate
0.273 3.25E-58 YMR124W_p YMR124W_p hom Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene; predicted to have a role in organelle organization
0.270 2.46E-57 YGL033W HOP2 hom Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair