YBR190W_d

Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W

Zygosity: Heterozygous strain
fixedexpanded
Profile for YBR190W / YBR190W

Click on Significant Values for Screen Details ID:SGTC_6|Compound:0844-0013|FD-Score:5.04|P-value:3.61E-6 ID:SGTC_8|Compound:0354-0001|FD-Score:3.61|P-value:6.47E-4 ID:SGTC_9|Compound:0092-0002|FD-Score:3.93|P-value:2.35E-4 ID:SGTC_15|Compound:0266-0086|FD-Score:4.28|P-value:6.87E-5 ID:SGTC_53|Compound:0973-0023|FD-Score:5.47|P-value:5.65E-7 ID:SGTC_118|Compound:0083-0097|FD-Score:3.88|P-value:2.70E-4 ID:SGTC_152|Compound:4469-0003|FD-Score:4.35|P-value:5.27E-5 ID:SGTC_188|Compound:3229-0966|FD-Score:5.78|P-value:1.39E-7 ID:SGTC_246|Compound:cycloheximide|FD-Score:5.19|P-value:1.91E-6 ID:SGTC_374|Compound:0880-0231|FD-Score:5.07|P-value:3.23E-6 ID:SGTC_408|Compound:cantharidin|FD-Score:4.10|P-value:1.31E-4 ID:SGTC_480|Compound:am 92016|FD-Score:3.98|P-value:1.97E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-4.63|P-value:2.13E-5 ID:SGTC_735|Compound:3076-0345|FD-Score:3.87|P-value:2.81E-4 ID:SGTC_817|Compound:1391-0715|FD-Score:4.98|P-value:4.74E-6 ID:SGTC_823|Compound:0417-1665|FD-Score:-3.75|P-value:4.67E-4 ID:SGTC_827|Compound:3253-0474|FD-Score:6.79|P-value:7.88E-10 ID:SGTC_828|Compound:2074-0507|FD-Score:-3.51|P-value:9.78E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:-7.34|P-value:4.08E-11 ID:SGTC_830|Compound:4076-0286|FD-Score:3.64|P-value:5.87E-4 ID:SGTC_831|Compound:k061-1017|FD-Score:4.61|P-value:2.00E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:6.51|P-value:3.60E-9 ID:SGTC_859|Compound:0439-0102|FD-Score:5.16|P-value:2.23E-6 ID:SGTC_984|Compound:1492-0255|FD-Score:-4.06|P-value:1.70E-4 ID:SGTC_1001|Compound:4048-4355|FD-Score:4.63|P-value:1.91E-5 ID:SGTC_1032|Compound:k061-1018|FD-Score:4.19|P-value:9.59E-5 ID:SGTC_1039|Compound:k821-0043|FD-Score:3.52|P-value:8.44E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.01|P-value:2.00E-4 ID:SGTC_1055|Compound:3448-0672|FD-Score:3.77|P-value:3.93E-4 ID:SGTC_1059|Compound:3448-6867|FD-Score:4.92|P-value:6.03E-6 ID:SGTC_1064|Compound:honokiol|FD-Score:5.97|P-value:5.46E-8 ID:SGTC_1078|Compound:idebenone|FD-Score:5.60|P-value:3.10E-7 ID:SGTC_1193|Compound:1488-0126|FD-Score:-3.87|P-value:3.18E-4 ID:SGTC_1261|Compound:0712-0010|FD-Score:9.06|P-value:4.04E-16 ID:SGTC_1547|Compound:harmine|FD-Score:-4.54|P-value:3.02E-5 ID:SGTC_1556|Compound:plumbagin|FD-Score:-4.41|P-value:4.77E-5 ID:SGTC_1643|Compound:st009866|FD-Score:-3.59|P-value:7.52E-4 ID:SGTC_1646|Compound:st011709|FD-Score:5.44|P-value:6.51E-7 ID:SGTC_1647|Compound:st011722|FD-Score:3.85|P-value:3.02E-4 ID:SGTC_1661|Compound:st013063|FD-Score:-4.29|P-value:7.55E-5 ID:SGTC_1754|Compound:st042065|FD-Score:-4.47|P-value:3.92E-5 ID:SGTC_1775|Compound:st081588|FD-Score:-3.52|P-value:9.45E-4 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:-4.93|P-value:6.54E-6 ID:SGTC_1800|Compound:st050079|FD-Score:-4.45|P-value:4.23E-5 ID:SGTC_1803|Compound:st050068|FD-Score:-4.17|P-value:1.16E-4 ID:SGTC_1818|Compound:st052136|FD-Score:-4.23|P-value:9.11E-5 ID:SGTC_1820|Compound:st053765|FD-Score:-3.96|P-value:2.37E-4 ID:SGTC_1862|Compound:st057513|FD-Score:4.23|P-value:8.24E-5 ID:SGTC_1961|Compound:st076550|FD-Score:3.55|P-value:7.78E-4 ID:SGTC_2017|Compound:5132927|FD-Score:4.28|P-value:6.98E-5 ID:SGTC_2050|Compound:5263056|FD-Score:7.64|P-value:5.53E-12 ID:SGTC_2099|Compound:5377090|FD-Score:3.62|P-value:6.19E-4 ID:SGTC_2172|Compound:5754775|FD-Score:4.48|P-value:3.36E-5 ID:SGTC_2257|Compound:7960413|FD-Score:-3.78|P-value:4.21E-4 ID:SGTC_2266|Compound:7929956|FD-Score:-3.70|P-value:5.34E-4 ID:SGTC_2268|Compound:7933382|FD-Score:-5.57|P-value:4.20E-7 ID:SGTC_2289|Compound:7946404|FD-Score:-3.99|P-value:2.10E-4 ID:SGTC_2321|Compound:7390090|FD-Score:-3.91|P-value:2.79E-4 ID:SGTC_2322|Compound:7413319|FD-Score:5.63|P-value:2.69E-7 ID:SGTC_2410|Compound:aloe-emodin-8-o-glycoside|FD-Score:3.56|P-value:7.65E-4 ID:SGTC_2413|Compound:inermin|FD-Score:-3.59|P-value:7.57E-4 ID:SGTC_2455|Compound:5377712|FD-Score:4.44|P-value:3.85E-5 ID:SGTC_2489|Compound:cantharidin|FD-Score:3.77|P-value:3.96E-4 ID:SGTC_2507|Compound:purpurin|FD-Score:-4.09|P-value:1.50E-4 ID:SGTC_2542|Compound:2-hydroxy-5 (6)epoxy-tetrahydrocaryophyllene|FD-Score:3.67|P-value:5.43E-4 ID:SGTC_2546|Compound:rhodinyl acetate|FD-Score:4.97|P-value:4.81E-6 ID:SGTC_2645|Compound:abamectin|FD-Score:-3.89|P-value:2.96E-4 ID:SGTC_2739|Compound:tacrine|FD-Score:-3.63|P-value:6.65E-4 ID:SGTC_2766|Compound:oltipraz|FD-Score:-4.64|P-value:2.03E-5 ID:SGTC_2780|Compound:5215298|FD-Score:5.92|P-value:6.94E-8 ID:SGTC_2817|Compound:7995342|FD-Score:-4.39|P-value:5.25E-5 ID:SGTC_2838|Compound:9002687|FD-Score:3.88|P-value:2.72E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-4.93|P-value:6.56E-6 ID:SGTC_2880|Compound:9042983|FD-Score:7.17|P-value:8.98E-11 ID:SGTC_2887|Compound:9044784|FD-Score:7.14|P-value:1.10E-10 ID:SGTC_2893|Compound:9048488|FD-Score:6.19|P-value:1.87E-8 ID:SGTC_2916|Compound:7875993|FD-Score:3.61|P-value:6.51E-4 ID:SGTC_2980|Compound:9014342|FD-Score:-3.63|P-value:6.79E-4 ID:SGTC_2993|Compound:9054257|FD-Score:4.93|P-value:5.67E-6 ID:SGTC_3071|Compound:9117417|FD-Score:4.10|P-value:1.29E-4 ID:SGTC_3081|Compound:9117243|FD-Score:7.56|P-value:8.94E-12 ID:SGTC_3085|Compound:9117376|FD-Score:4.20|P-value:9.21E-5 ID:SGTC_3093|Compound:9117344|FD-Score:3.68|P-value:5.19E-4 ID:SGTC_3094|Compound:9117742|FD-Score:3.57|P-value:7.31E-4 ID:SGTC_3100|Compound:9120536|FD-Score:3.97|P-value:2.04E-4 ID:SGTC_3108|Compound:9121785|FD-Score:-4.06|P-value:1.65E-4 ID:SGTC_3207|Compound:9114163|FD-Score:3.72|P-value:4.65E-4 ID:SGTC_3266|Compound:9136860|FD-Score:-5.89|P-value:9.25E-8 ID:SGTC_3346|Compound:9158254|FD-Score:4.58|P-value:2.27E-5 ID:SGTC_6|Compound:0844-0013|FD-Score:5.04|P-value:3.61E-6 ID:SGTC_8|Compound:0354-0001|FD-Score:3.61|P-value:6.47E-4 ID:SGTC_9|Compound:0092-0002|FD-Score:3.93|P-value:2.35E-4 ID:SGTC_15|Compound:0266-0086|FD-Score:4.28|P-value:6.87E-5 ID:SGTC_53|Compound:0973-0023|FD-Score:5.47|P-value:5.65E-7 ID:SGTC_118|Compound:0083-0097|FD-Score:3.88|P-value:2.70E-4 ID:SGTC_152|Compound:4469-0003|FD-Score:4.35|P-value:5.27E-5 ID:SGTC_188|Compound:3229-0966|FD-Score:5.78|P-value:1.39E-7 ID:SGTC_246|Compound:cycloheximide|FD-Score:5.19|P-value:1.91E-6 ID:SGTC_374|Compound:0880-0231|FD-Score:5.07|P-value:3.23E-6 ID:SGTC_408|Compound:cantharidin|FD-Score:4.10|P-value:1.31E-4 ID:SGTC_480|Compound:am 92016|FD-Score:3.98|P-value:1.97E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-4.63|P-value:2.13E-5 ID:SGTC_735|Compound:3076-0345|FD-Score:3.87|P-value:2.81E-4 ID:SGTC_817|Compound:1391-0715|FD-Score:4.98|P-value:4.74E-6 ID:SGTC_823|Compound:0417-1665|FD-Score:-3.75|P-value:4.67E-4 ID:SGTC_827|Compound:3253-0474|FD-Score:6.79|P-value:7.88E-10 ID:SGTC_828|Compound:2074-0507|FD-Score:-3.51|P-value:9.78E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:-7.34|P-value:4.08E-11 ID:SGTC_830|Compound:4076-0286|FD-Score:3.64|P-value:5.87E-4 ID:SGTC_831|Compound:k061-1017|FD-Score:4.61|P-value:2.00E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:6.51|P-value:3.60E-9 ID:SGTC_859|Compound:0439-0102|FD-Score:5.16|P-value:2.23E-6 ID:SGTC_984|Compound:1492-0255|FD-Score:-4.06|P-value:1.70E-4 ID:SGTC_1001|Compound:4048-4355|FD-Score:4.63|P-value:1.91E-5 ID:SGTC_1032|Compound:k061-1018|FD-Score:4.19|P-value:9.59E-5 ID:SGTC_1039|Compound:k821-0043|FD-Score:3.52|P-value:8.44E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.01|P-value:2.00E-4 ID:SGTC_1055|Compound:3448-0672|FD-Score:3.77|P-value:3.93E-4 ID:SGTC_1059|Compound:3448-6867|FD-Score:4.92|P-value:6.03E-6 ID:SGTC_1064|Compound:honokiol|FD-Score:5.97|P-value:5.46E-8 ID:SGTC_1078|Compound:idebenone|FD-Score:5.60|P-value:3.10E-7 ID:SGTC_1193|Compound:1488-0126|FD-Score:-3.87|P-value:3.18E-4 ID:SGTC_1261|Compound:0712-0010|FD-Score:9.06|P-value:4.04E-16 ID:SGTC_1547|Compound:harmine|FD-Score:-4.54|P-value:3.02E-5 ID:SGTC_1556|Compound:plumbagin|FD-Score:-4.41|P-value:4.77E-5 ID:SGTC_1643|Compound:st009866|FD-Score:-3.59|P-value:7.52E-4 ID:SGTC_1646|Compound:st011709|FD-Score:5.44|P-value:6.51E-7 ID:SGTC_1647|Compound:st011722|FD-Score:3.85|P-value:3.02E-4 ID:SGTC_1661|Compound:st013063|FD-Score:-4.29|P-value:7.55E-5 ID:SGTC_1754|Compound:st042065|FD-Score:-4.47|P-value:3.92E-5 ID:SGTC_1775|Compound:st081588|FD-Score:-3.52|P-value:9.45E-4 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:-4.93|P-value:6.54E-6 ID:SGTC_1800|Compound:st050079|FD-Score:-4.45|P-value:4.23E-5 ID:SGTC_1803|Compound:st050068|FD-Score:-4.17|P-value:1.16E-4 ID:SGTC_1818|Compound:st052136|FD-Score:-4.23|P-value:9.11E-5 ID:SGTC_1820|Compound:st053765|FD-Score:-3.96|P-value:2.37E-4 ID:SGTC_1862|Compound:st057513|FD-Score:4.23|P-value:8.24E-5 ID:SGTC_1961|Compound:st076550|FD-Score:3.55|P-value:7.78E-4 ID:SGTC_2017|Compound:5132927|FD-Score:4.28|P-value:6.98E-5 ID:SGTC_2050|Compound:5263056|FD-Score:7.64|P-value:5.53E-12 ID:SGTC_2099|Compound:5377090|FD-Score:3.62|P-value:6.19E-4 ID:SGTC_2172|Compound:5754775|FD-Score:4.48|P-value:3.36E-5 ID:SGTC_2257|Compound:7960413|FD-Score:-3.78|P-value:4.21E-4 ID:SGTC_2266|Compound:7929956|FD-Score:-3.70|P-value:5.34E-4 ID:SGTC_2268|Compound:7933382|FD-Score:-5.57|P-value:4.20E-7 ID:SGTC_2289|Compound:7946404|FD-Score:-3.99|P-value:2.10E-4 ID:SGTC_2321|Compound:7390090|FD-Score:-3.91|P-value:2.79E-4 ID:SGTC_2322|Compound:7413319|FD-Score:5.63|P-value:2.69E-7 ID:SGTC_2410|Compound:aloe-emodin-8-o-glycoside|FD-Score:3.56|P-value:7.65E-4 ID:SGTC_2413|Compound:inermin|FD-Score:-3.59|P-value:7.57E-4 ID:SGTC_2455|Compound:5377712|FD-Score:4.44|P-value:3.85E-5 ID:SGTC_2489|Compound:cantharidin|FD-Score:3.77|P-value:3.96E-4 ID:SGTC_2507|Compound:purpurin|FD-Score:-4.09|P-value:1.50E-4 ID:SGTC_2542|Compound:2-hydroxy-5 (6)epoxy-tetrahydrocaryophyllene|FD-Score:3.67|P-value:5.43E-4 ID:SGTC_2546|Compound:rhodinyl acetate|FD-Score:4.97|P-value:4.81E-6 ID:SGTC_2645|Compound:abamectin|FD-Score:-3.89|P-value:2.96E-4 ID:SGTC_2739|Compound:tacrine|FD-Score:-3.63|P-value:6.65E-4 ID:SGTC_2766|Compound:oltipraz|FD-Score:-4.64|P-value:2.03E-5 ID:SGTC_2780|Compound:5215298|FD-Score:5.92|P-value:6.94E-8 ID:SGTC_2817|Compound:7995342|FD-Score:-4.39|P-value:5.25E-5 ID:SGTC_2838|Compound:9002687|FD-Score:3.88|P-value:2.72E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-4.93|P-value:6.56E-6 ID:SGTC_2880|Compound:9042983|FD-Score:7.17|P-value:8.98E-11 ID:SGTC_2887|Compound:9044784|FD-Score:7.14|P-value:1.10E-10 ID:SGTC_2893|Compound:9048488|FD-Score:6.19|P-value:1.87E-8 ID:SGTC_2916|Compound:7875993|FD-Score:3.61|P-value:6.51E-4 ID:SGTC_2980|Compound:9014342|FD-Score:-3.63|P-value:6.79E-4 ID:SGTC_2993|Compound:9054257|FD-Score:4.93|P-value:5.67E-6 ID:SGTC_3071|Compound:9117417|FD-Score:4.10|P-value:1.29E-4 ID:SGTC_3081|Compound:9117243|FD-Score:7.56|P-value:8.94E-12 ID:SGTC_3085|Compound:9117376|FD-Score:4.20|P-value:9.21E-5 ID:SGTC_3093|Compound:9117344|FD-Score:3.68|P-value:5.19E-4 ID:SGTC_3094|Compound:9117742|FD-Score:3.57|P-value:7.31E-4 ID:SGTC_3100|Compound:9120536|FD-Score:3.97|P-value:2.04E-4 ID:SGTC_3108|Compound:9121785|FD-Score:-4.06|P-value:1.65E-4 ID:SGTC_3207|Compound:9114163|FD-Score:3.72|P-value:4.65E-4 ID:SGTC_3266|Compound:9136860|FD-Score:-5.89|P-value:9.25E-8 ID:SGTC_3346|Compound:9158254|FD-Score:4.58|P-value:2.27E-5

Top fitness defect scores for YBR190W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1261 0712-0010 9.06 12.7 µM 4.04E-16 RNA processing & uracil transport 2 6.44E-20 3.00
2 SGTC_2050 5263056 7.64 171.0 µM 5.53E-12 fatty acid desaturase (OLE1) 8 1.09E-14 0.15
3 SGTC_3081 9117243 7.56 49.5 µM 8.94E-12 fatty acid desaturase (OLE1) 4 2.00E-14 4.40E-4
4 SGTC_2880 9042983 7.17 58.4 µM 8.98E-11 fatty acid desaturase (OLE1) 2 3.67E-13 0.77
5 SGTC_2887 9044784 7.14 58.4 µM 1.10E-10 fatty acid desaturase (OLE1) 5 4.74E-13 0.14
6 SGTC_827 3253-0474 6.79 693.0 µM 7.88E-10 2 5.68E-12 2.26
7 SGTC_832 4083-0019 6.51 164.0 µM 3.60E-9 translation 7 3.86E-11 0.14
8 SGTC_2893 9048488 6.19 26.0 µM 1.87E-8 fatty acid desaturase (OLE1) 1 3.07E-10 0.79
9 SGTC_1064 honokiol 5.97 6.8 µM 5.46E-8 3 1.19E-9 1.17
10 SGTC_2780 5215298 5.92 71.4 µM 6.94E-8 4 1.60E-9 0.01
11 SGTC_188 3229-0966 5.78 278.5 µM 1.39E-7 7 3.84E-9 0.28
12 SGTC_2322 7413319 5.63 38.2 µM 2.69E-7 ERAD & cell cycle 13 8.82E-9 0.16
13 SGTC_1078 idebenone 5.60 36.1 µM 3.10E-7 Golgi 1 1.05E-8 1.38
14 SGTC_53 0973-0023 5.47 40.0 µM 5.65E-7 RNA processing & uracil transport 3 2.24E-8 0.13
15 SGTC_1646 st011709 5.44 75.6 µM 6.51E-7 3 2.68E-8 0.43
16 SGTC_246 cycloheximide 5.19 667.0 µM 1.91E-6 6 1.04E-7 0.28
17 SGTC_859 0439-0102 5.16 54.6 µM 2.23E-6 redox potentiating 3 1.26E-7 0.50
18 SGTC_374 0880-0231 5.07 82.3 µM 3.23E-6 iron homeostasis 5 2.01E-7 0.07
19 SGTC_6 0844-0013 5.04 19.8 µM 3.61E-6 2 2.31E-7 0.79
20 SGTC_817 1391-0715 4.98 46.0 µM 4.74E-6 2 3.25E-7 0.32

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.274 1.66E-58 YPL131W RPL5 het Ribosomal 60S subunit protein L5; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly
0.259 1.26E-52 YLR009W RLP24 het Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp
0.221 2.19E-38 YOL120C RPL18A het Ribosomal 60S subunit protein L18A; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation; homologous to mammalian ribosomal protein L18, no bacterial homolog; RPL18A has a paralog, RPL18B, that arose from the whole genome duplication
0.203 1.41E-32 YGL055W OLE1 het Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
0.189 2.12E-28 YJR007W SUI2 het Alpha subunit of the translation initiation factor eIF2; eIF2 is involved in identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP; protein abundance increases in response to DNA replication stress
0.169 7.88E-23 YPL093W NOG1 het Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
0.168 1.35E-22 YPL143W RPL33A het Ribosomal 60S subunit protein L33A; N-terminally acetylated; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33A has a paralog, RPL33B, that arose from the whole genome duplication
0.165 7.77E-22 YDL226C GCS1 hom ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
0.157 4.89E-20 YDR429C TIF35 het eIF3g subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation; stimulates resumption of ribosomal scanning during translation reinitiation
0.153 4.51E-19 YJL143W TIM17 het Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex
0.148 7.06E-18 YOR206W NOC2 het Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors
0.147 1.42E-17 YLR075W RPL10 het Ribosomal 60S subunit protein L10; responsible for joining the 40S and 60S subunits; regulates translation initiation; similar to members of the QM gene family; homologous to mammalian ribosomal protein L10 and bacterial L16; protein abundance increases in response to DNA replication stress; mutations in the human ortholog are associated with development of T-cell acute lymphoblastic leukemia and similar changes in the yeast gene result in ribosome biogenesis defects
0.143 8.26E-17 YLR076C_d YLR076C_d het Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPL10 which encodes the ribosomal protein L10
0.128 9.17E-14 YLR048W RPS0B hom Protein component of the small (40S) ribosomal subunit; RPS0B has a paralog, RPS0A, that arose from the whole genome duplication; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2
0.128 1.13E-13 YNR053C NOG2 het Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation