| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|
| 0.137 |
1.81E-15 |
YKL182W |
FAS1 |
het |
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities |
| 0.130 |
4.03E-14 |
YHR025W |
THR1 |
hom |
Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway |
| 0.115 |
2.77E-11 |
YDR530C |
APA2 |
hom |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II; AP4A phosphorylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; APA2 has a paralog, APA1, that arose from the whole genome duplication |
| 0.114 |
3.22E-11 |
YGR077C |
PEX8 |
hom |
Intraperoxisomal organizer of the peroxisomal import machinery; organizes the formation of the importomer complex, bridging the docking complex with the RING finger complex; tightly associated with the lumenal face of the peroxisomal membrane; essential for peroxisome biogenesis; binds PTS1-signal receptor Pex5p, and PTS2-signal receptor Pex7p |
| 0.109 |
2.13E-10 |
YGR161W-C_p |
YGR161W-C_p |
hom |
Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species |
| 0.102 |
2.86E-9 |
YPR047W |
MSF1 |
hom |
Mitochondrial phenylalanyl-tRNA synthetase, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase |
| 0.102 |
2.98E-9 |
YMR222C |
FSH2 |
hom |
Putative serine hydrolase that localizes to the cytoplasm; sequence is similar to S. cerevisiae Fsh1p and Fsh3p and the human candidate tumor suppressor OVCA2 |
| 0.097 |
1.83E-8 |
YFR015C |
GSY1 |
hom |
Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress |
| 0.092 |
8.93E-8 |
YJL171C |
YJL171C |
hom |
GPI-anchored cell wall protein of unknown function; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein; protein abundance increases in response to DNA replication stress |
| 0.087 |
3.93E-7 |
YNL301C |
RPL18B |
hom |
Ribosomal 60S subunit protein L18B; homologous to mammalian ribosomal protein L18, no bacterial homolog; RPL18B has a paralog, RPL18A, that arose from the whole genome duplication |
| 0.086 |
5.79E-7 |
YDL238C |
GUD1 |
hom |
Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures |
| 0.086 |
6.71E-7 |
YGR044C |
RME1 |
hom |
Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation; relocalizes from nucleus to cytoplasm upon DNA replication stress |
| 0.084 |
1.09E-6 |
YDR128W |
MTC5 |
hom |
Subunit of the SEA (Seh1-associated) complex; SEA is a coatomer-related complex that associates dynamically with the vacuole; has N-terminal WD-40 repeats and a C-terminal RING motif; mtc5 is synthetically sick with cdc13-1; relative distribution to vacuolar membrane punctae decreases upon DNA replication stress |
| 0.083 |
1.49E-6 |
YGL138C_p |
YGL138C_p |
hom |
Putative protein of unknown function; has no significant sequence similarity to any known protein |
| 0.082 |
1.76E-6 |
YGR092W |
DBF2 |
hom |
Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis |
