YCR102W-A_d

Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data

Zygosity: Homozygous strain
fixedexpanded
Profile for YCR102W-A / YCR102W-A

Click on Significant Values for Screen Details ID:SGTC_12|Compound:0849-0099|FD-Score:2.95|P-value:5.50E-4 ID:SGTC_67|Compound:0335-0847|FD-Score:3.20|P-value:2.02E-4 ID:SGTC_166|Compound:k072-0058|FD-Score:-6.74|P-value:1.22E-13 ID:SGTC_169|Compound:k015-0017|FD-Score:3.03|P-value:4.04E-4 ID:SGTC_562|Compound:3772-2733|FD-Score:3.30|P-value:1.36E-4 ID:SGTC_613|Compound:3914-0030|FD-Score:-3.83|P-value:1.70E-5 ID:SGTC_711|Compound:k292-0785|FD-Score:-3.22|P-value:2.59E-4 ID:SGTC_740|Compound:k014-0057|FD-Score:2.81|P-value:9.32E-4 ID:SGTC_750|Compound:4073-0104|FD-Score:-3.51|P-value:7.40E-5 ID:SGTC_940|Compound:3232-1287|FD-Score:4.05|P-value:4.11E-6 ID:SGTC_942|Compound:3253-1115|FD-Score:4.12|P-value:2.82E-6 ID:SGTC_967|Compound:1306-0166|FD-Score:3.10|P-value:3.07E-4 ID:SGTC_1101|Compound:ebselen|FD-Score:3.05|P-value:3.71E-4 ID:SGTC_1107|Compound:amlodipine|FD-Score:-6.33|P-value:3.27E-12 ID:SGTC_1115|Compound:galangin|FD-Score:3.00|P-value:4.56E-4 ID:SGTC_1118|Compound:chelidonine|FD-Score:4.50|P-value:3.59E-7 ID:SGTC_1291|Compound:0993-0025|FD-Score:4.91|P-value:3.33E-8 ID:SGTC_1459|Compound:k035-0031|FD-Score:-3.21|P-value:2.63E-4 ID:SGTC_1465|Compound:k213-0056|FD-Score:-3.09|P-value:4.25E-4 ID:SGTC_1650|Compound:st011916|FD-Score:2.80|P-value:9.75E-4 ID:SGTC_1690|Compound:st023502|FD-Score:3.86|P-value:1.02E-5 ID:SGTC_1727|Compound:st034309|FD-Score:3.04|P-value:3.90E-4 ID:SGTC_1737|Compound:st035557|FD-Score:-3.13|P-value:3.65E-4 ID:SGTC_1911|Compound:st060208|FD-Score:2.83|P-value:8.72E-4 ID:SGTC_1916|Compound:st067606|FD-Score:-3.36|P-value:1.43E-4 ID:SGTC_1947|Compound:st076332|FD-Score:-2.98|P-value:6.67E-4 ID:SGTC_2112|Compound:5488546|FD-Score:-3.36|P-value:1.44E-4 ID:SGTC_2229|Compound:7354935|FD-Score:3.39|P-value:9.19E-5 ID:SGTC_2405|Compound:ticlatone|FD-Score:-5.35|P-value:3.25E-9 ID:SGTC_2417|Compound:cerulenin|FD-Score:-2.94|P-value:7.67E-4 ID:SGTC_2420|Compound:aureobasidin a|FD-Score:3.93|P-value:7.49E-6 ID:SGTC_2492|Compound:derrusnin|FD-Score:2.95|P-value:5.51E-4 ID:SGTC_2516|Compound:gossypol|FD-Score:3.24|P-value:1.70E-4 ID:SGTC_2523|Compound:spermine|FD-Score:2.86|P-value:7.82E-4 ID:SGTC_2614|Compound:arthonioic acid|FD-Score:-11.00|P-value:1.74E-33 ID:SGTC_2851|Compound:9015922|FD-Score:-2.92|P-value:8.31E-4 ID:SGTC_2853|Compound:9015042|FD-Score:-3.14|P-value:3.59E-4 ID:SGTC_2855|Compound:9016525|FD-Score:3.46|P-value:6.57E-5 ID:SGTC_2922|Compound:7999257|FD-Score:2.96|P-value:5.29E-4 ID:SGTC_2927|Compound:9011802|FD-Score:-3.07|P-value:4.66E-4 ID:SGTC_2962|Compound:9082311|FD-Score:-4.40|P-value:9.77E-7 ID:SGTC_2963|Compound:9082507|FD-Score:-3.03|P-value:5.54E-4 ID:SGTC_2981|Compound:9013952|FD-Score:-2.94|P-value:7.62E-4 ID:SGTC_2997|Compound:9067075|FD-Score:-2.88|P-value:9.69E-4 ID:SGTC_3043|Compound:9092303|FD-Score:-2.98|P-value:6.58E-4 ID:SGTC_3056|Compound:9094900|FD-Score:-2.89|P-value:9.34E-4 ID:SGTC_3103|Compound:9120822|FD-Score:4.84|P-value:4.89E-8 ID:SGTC_3107|Compound:9121808|FD-Score:3.26|P-value:1.58E-4 ID:SGTC_3109|Compound:9122853|FD-Score:3.43|P-value:7.53E-5 ID:SGTC_3208|Compound:9114115|FD-Score:-3.27|P-value:2.07E-4 ID:SGTC_12|Compound:0849-0099|FD-Score:2.95|P-value:5.50E-4 ID:SGTC_67|Compound:0335-0847|FD-Score:3.20|P-value:2.02E-4 ID:SGTC_166|Compound:k072-0058|FD-Score:-6.74|P-value:1.22E-13 ID:SGTC_169|Compound:k015-0017|FD-Score:3.03|P-value:4.04E-4 ID:SGTC_562|Compound:3772-2733|FD-Score:3.30|P-value:1.36E-4 ID:SGTC_613|Compound:3914-0030|FD-Score:-3.83|P-value:1.70E-5 ID:SGTC_711|Compound:k292-0785|FD-Score:-3.22|P-value:2.59E-4 ID:SGTC_740|Compound:k014-0057|FD-Score:2.81|P-value:9.32E-4 ID:SGTC_750|Compound:4073-0104|FD-Score:-3.51|P-value:7.40E-5 ID:SGTC_940|Compound:3232-1287|FD-Score:4.05|P-value:4.11E-6 ID:SGTC_942|Compound:3253-1115|FD-Score:4.12|P-value:2.82E-6 ID:SGTC_967|Compound:1306-0166|FD-Score:3.10|P-value:3.07E-4 ID:SGTC_1101|Compound:ebselen|FD-Score:3.05|P-value:3.71E-4 ID:SGTC_1107|Compound:amlodipine|FD-Score:-6.33|P-value:3.27E-12 ID:SGTC_1115|Compound:galangin|FD-Score:3.00|P-value:4.56E-4 ID:SGTC_1118|Compound:chelidonine|FD-Score:4.50|P-value:3.59E-7 ID:SGTC_1291|Compound:0993-0025|FD-Score:4.91|P-value:3.33E-8 ID:SGTC_1459|Compound:k035-0031|FD-Score:-3.21|P-value:2.63E-4 ID:SGTC_1465|Compound:k213-0056|FD-Score:-3.09|P-value:4.25E-4 ID:SGTC_1650|Compound:st011916|FD-Score:2.80|P-value:9.75E-4 ID:SGTC_1690|Compound:st023502|FD-Score:3.86|P-value:1.02E-5 ID:SGTC_1727|Compound:st034309|FD-Score:3.04|P-value:3.90E-4 ID:SGTC_1737|Compound:st035557|FD-Score:-3.13|P-value:3.65E-4 ID:SGTC_1911|Compound:st060208|FD-Score:2.83|P-value:8.72E-4 ID:SGTC_1916|Compound:st067606|FD-Score:-3.36|P-value:1.43E-4 ID:SGTC_1947|Compound:st076332|FD-Score:-2.98|P-value:6.67E-4 ID:SGTC_2112|Compound:5488546|FD-Score:-3.36|P-value:1.44E-4 ID:SGTC_2229|Compound:7354935|FD-Score:3.39|P-value:9.19E-5 ID:SGTC_2405|Compound:ticlatone|FD-Score:-5.35|P-value:3.25E-9 ID:SGTC_2417|Compound:cerulenin|FD-Score:-2.94|P-value:7.67E-4 ID:SGTC_2420|Compound:aureobasidin a|FD-Score:3.93|P-value:7.49E-6 ID:SGTC_2492|Compound:derrusnin|FD-Score:2.95|P-value:5.51E-4 ID:SGTC_2516|Compound:gossypol|FD-Score:3.24|P-value:1.70E-4 ID:SGTC_2523|Compound:spermine|FD-Score:2.86|P-value:7.82E-4 ID:SGTC_2614|Compound:arthonioic acid|FD-Score:-11.00|P-value:1.74E-33 ID:SGTC_2851|Compound:9015922|FD-Score:-2.92|P-value:8.31E-4 ID:SGTC_2853|Compound:9015042|FD-Score:-3.14|P-value:3.59E-4 ID:SGTC_2855|Compound:9016525|FD-Score:3.46|P-value:6.57E-5 ID:SGTC_2922|Compound:7999257|FD-Score:2.96|P-value:5.29E-4 ID:SGTC_2927|Compound:9011802|FD-Score:-3.07|P-value:4.66E-4 ID:SGTC_2962|Compound:9082311|FD-Score:-4.40|P-value:9.77E-7 ID:SGTC_2963|Compound:9082507|FD-Score:-3.03|P-value:5.54E-4 ID:SGTC_2981|Compound:9013952|FD-Score:-2.94|P-value:7.62E-4 ID:SGTC_2997|Compound:9067075|FD-Score:-2.88|P-value:9.69E-4 ID:SGTC_3043|Compound:9092303|FD-Score:-2.98|P-value:6.58E-4 ID:SGTC_3056|Compound:9094900|FD-Score:-2.89|P-value:9.34E-4 ID:SGTC_3103|Compound:9120822|FD-Score:4.84|P-value:4.89E-8 ID:SGTC_3107|Compound:9121808|FD-Score:3.26|P-value:1.58E-4 ID:SGTC_3109|Compound:9122853|FD-Score:3.43|P-value:7.53E-5 ID:SGTC_3208|Compound:9114115|FD-Score:-3.27|P-value:2.07E-4

Top fitness defect scores for YCR102W-A deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1291 0993-0025 4.91 5.8 µM 3.33E-8 6 4.62E-7
2 SGTC_3103 9120822 4.84 49.5 µM 4.89E-8 6 6.37E-7
3 SGTC_1118 chelidonine 4.50 707.5 nM 3.59E-7 10 3.39E-6
4 SGTC_942 3253-1115 4.12 227.0 µM 2.82E-6 24 1.91E-5
5 SGTC_940 3232-1287 4.05 54.8 µM 4.11E-6 NEO1 36 2.61E-5
6 SGTC_2420 aureobasidin a 3.93 50.0 nM 7.49E-6 49 4.31E-5
7 SGTC_1690 st023502 3.86 41.2 µM 1.02E-5 calcium & mitochondrial duress 10 5.57E-5
8 SGTC_2855 9016525 3.46 58.4 µM 6.57E-5 36 2.67E-4
9 SGTC_3109 9122853 3.43 49.5 µM 7.53E-5 20 2.99E-4
10 SGTC_2229 7354935 3.39 190.0 µM 9.19E-5 RSC complex & mRNA processing 15 3.53E-4
11 SGTC_562 3772-2733 3.30 112.0 µM 1.36E-4 ERG2 117 4.91E-4
12 SGTC_3107 9121808 3.26 49.5 µM 1.58E-4 22 5.57E-4
13 SGTC_2516 gossypol 3.24 71.5 µM 1.70E-4 41 5.92E-4
14 SGTC_67 0335-0847 3.20 266.0 µM 2.02E-4 ubiquinone biosynthesis & proteasome 166 6.85E-4
15 SGTC_967 1306-0166 3.10 352.0 µM 3.07E-4 77 9.71E-4
16 SGTC_1101 ebselen 3.05 5.3 µM 3.71E-4 56 0.00114
17 SGTC_1727 st034309 3.04 9.9 µM 3.90E-4 102 0.00119
18 SGTC_169 k015-0017 3.03 16.0 µM 4.04E-4 48 0.00122
19 SGTC_1115 galangin 3.00 695.7 nM 4.56E-4 RPP1 & pyrimidine depletion 55 0.00136
20 SGTC_2922 7999257 2.96 32.5 µM 5.29E-4 37 0.00154

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.396 1.59E-126 YGL146C_p RRT6_p hom Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; contains two putative transmembrane spans, but no significant homology to other known proteins
0.366 5.90E-107 YEL049W PAU2 hom Member of the seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
0.335 1.55E-88 YER066W_p RRT13_p hom Putative protein of unknown function; non-essential gene identified in a screen for mutants with decreased levels of rDNA transcription
0.293 3.11E-67 YLR395C COX8 hom Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
0.259 9.64E-53 YOR300W_d YOR300W_d hom Dubious open reading frame, unlikely to encode a protein; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7
0.255 6.34E-51 YER060W-A FCY22 hom Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function
0.247 8.03E-48 YGR015C_p YGR015C_p hom Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
0.231 1.04E-41 YJR098C_p YJR098C_p hom Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
0.228 1.05E-40 YER071C_p TDA2_p hom Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; null mutant is sensitive to expression of the top1-T722A allele
0.221 1.71E-38 YNL220W ADE12 hom Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence
0.218 1.71E-37 YJL043W_p YJL043W_p hom Putative protein of unknown function; YJL043W is a non-essential gene
0.214 5.06E-36 YMR147W_p YMR147W_p hom Putative protein of unknown function
0.211 5.33E-35 YNL042W BOP3 hom Protein of unknown function, potential Cdc28p substrate; overproduction confers resistance to methylmercury
0.207 9.56E-34 YNR067C DSE4 hom Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother
0.207 1.23E-33 YFL063W_d YFL063W_d hom Dubious open reading frame, based on available experimental and comparative sequence data