YDL195W / SEC31

Component of the Sec13p-Sec31p complex of the COPII vesicle coat, required for vesicle formation in ER to Golgi transport; mutant has increased aneuploidy tolerance

Zygosity: Heterozygous strain
fixedexpanded
Profile for YDL195W / SEC31

Click on Significant Values for Screen Details ID:SGTC_3|Compound:0833-0587|FD-Score:6.41|P-value:1.20E-6 ID:SGTC_41|Compound:0478-0632|FD-Score:11.80|P-value:2.48E-18 ID:SGTC_43|Compound:0570-0105|FD-Score:14.70|P-value:1.54E-27 ID:SGTC_46|Compound:0329-0187a|FD-Score:7.38|P-value:2.81E-8 ID:SGTC_58|Compound:0957-0393|FD-Score:7.81|P-value:4.51E-9 ID:SGTC_77|Compound:0828-0286|FD-Score:11.00|P-value:2.88E-16 ID:SGTC_89|Compound:0302-0250|FD-Score:5.18|P-value:6.97E-5 ID:SGTC_103|Compound:0844-0104|FD-Score:5.38|P-value:3.81E-5 ID:SGTC_106|Compound:0092-0003|FD-Score:10.00|P-value:8.99E-14 ID:SGTC_109|Compound:0132-0036|FD-Score:4.32|P-value:7.55E-4 ID:SGTC_126|Compound:0417-1624|FD-Score:16.00|P-value:2.73E-32 ID:SGTC_131|Compound:0141-0277|FD-Score:4.58|P-value:3.83E-4 ID:SGTC_132|Compound:0417-1715|FD-Score:5.67|P-value:1.54E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:10.50|P-value:4.56E-15 ID:SGTC_145|Compound:3737-0113|FD-Score:8.64|P-value:1.03E-10 ID:SGTC_153|Compound:4077-0274|FD-Score:4.61|P-value:3.53E-4 ID:SGTC_156|Compound:3474-0145|FD-Score:12.40|P-value:4.42E-20 ID:SGTC_157|Compound:1348-1695|FD-Score:13.60|P-value:9.14E-24 ID:SGTC_161|Compound:4065-0411|FD-Score:8.84|P-value:3.94E-11 ID:SGTC_191|Compound:3914-0123|FD-Score:5.06|P-value:9.90E-5 ID:SGTC_208|Compound:k072-0098|FD-Score:11.10|P-value:1.32E-16 ID:SGTC_211|Compound:3455-0679|FD-Score:6.14|P-value:3.16E-6 ID:SGTC_263|Compound:alizarin|FD-Score:8.26|P-value:6.12E-10 ID:SGTC_290|Compound:2043-6722|FD-Score:5.06|P-value:9.99E-5 ID:SGTC_311|Compound:1315-0136|FD-Score:6.77|P-value:3.20E-7 ID:SGTC_330|Compound:1488-0319|FD-Score:5.44|P-value:3.15E-5 ID:SGTC_342|Compound:k048-0088|FD-Score:5.69|P-value:1.43E-5 ID:SGTC_349|Compound:k015-0014|FD-Score:6.08|P-value:3.83E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:5.17|P-value:7.27E-5 ID:SGTC_352|Compound:k048-0007|FD-Score:5.36|P-value:4.09E-5 ID:SGTC_354|Compound:2783-3500|FD-Score:4.93|P-value:1.44E-4 ID:SGTC_356|Compound:1634-0012|FD-Score:9.85|P-value:2.13E-13 ID:SGTC_362|Compound:0310-0100|FD-Score:5.76|P-value:1.13E-5 ID:SGTC_363|Compound:0455-0021|FD-Score:5.93|P-value:6.44E-6 ID:SGTC_372|Compound:0155-0182|FD-Score:-4.83|P-value:1.79E-4 ID:SGTC_389|Compound:tpck|FD-Score:4.48|P-value:4.97E-4 ID:SGTC_394|Compound:menadione|FD-Score:6.79|P-value:2.91E-7 ID:SGTC_444|Compound:curcumin|FD-Score:5.61|P-value:1.84E-5 ID:SGTC_483|Compound:fpl-64176|FD-Score:6.16|P-value:2.99E-6 ID:SGTC_524|Compound:r073-0010|FD-Score:13.50|P-value:1.43E-23 ID:SGTC_525|Compound:k781-2675|FD-Score:38.70|P-value:2.50E-179 ID:SGTC_538|Compound:2922-0838|FD-Score:5.27|P-value:5.38E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:6.17|P-value:2.84E-6 ID:SGTC_543|Compound:3844-1095|FD-Score:4.43|P-value:5.66E-4 ID:SGTC_550|Compound:4123-0385|FD-Score:4.39|P-value:6.20E-4 ID:SGTC_557|Compound:1315-0110|FD-Score:6.11|P-value:3.49E-6 ID:SGTC_572|Compound:0960-0087|FD-Score:9.72|P-value:4.19E-13 ID:SGTC_576|Compound:1073-0113|FD-Score:12.10|P-value:3.32E-19 ID:SGTC_586|Compound:0957-0265|FD-Score:9.79|P-value:2.96E-13 ID:SGTC_590|Compound:k048-0076|FD-Score:4.59|P-value:3.67E-4 ID:SGTC_595|Compound:3909-8003|FD-Score:4.50|P-value:4.66E-4 ID:SGTC_619|Compound:1652-1634|FD-Score:5.10|P-value:8.87E-5 ID:SGTC_647|Compound:0140-0236|FD-Score:8.91|P-value:2.73E-11 ID:SGTC_657|Compound:3534-0529|FD-Score:6.03|P-value:4.67E-6 ID:SGTC_667|Compound:1498-1044|FD-Score:5.32|P-value:4.56E-5 ID:SGTC_690|Compound:glyoxal|FD-Score:5.45|P-value:3.10E-5 ID:SGTC_699|Compound:0375-0592|FD-Score:9.89|P-value:1.67E-13 ID:SGTC_733|Compound:4069-0007|FD-Score:4.87|P-value:1.70E-4 ID:SGTC_734|Compound:2023-0417|FD-Score:4.35|P-value:6.89E-4 ID:SGTC_741|Compound:4582-0002|FD-Score:5.19|P-value:6.82E-5 ID:SGTC_756|Compound:0508-1999|FD-Score:4.37|P-value:6.59E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:12.60|P-value:8.93E-21 ID:SGTC_786|Compound:4544-0069|FD-Score:6.64|P-value:5.23E-7 ID:SGTC_790|Compound:1575-0012|FD-Score:7.00|P-value:1.30E-7 ID:SGTC_805|Compound:3852-0218|FD-Score:4.26|P-value:8.71E-4 ID:SGTC_828|Compound:2074-0507|FD-Score:5.46|P-value:2.94E-5 ID:SGTC_845|Compound:0330-0138|FD-Score:5.23|P-value:6.01E-5 ID:SGTC_848|Compound:0368-0089|FD-Score:6.87|P-value:2.16E-7 ID:SGTC_855|Compound:0428-0020|FD-Score:11.50|P-value:1.58E-17 ID:SGTC_878|Compound:0828-0289|FD-Score:11.90|P-value:7.54E-19 ID:SGTC_879|Compound:0831-1030|FD-Score:4.70|P-value:2.74E-4 ID:SGTC_893|Compound:0958-0369|FD-Score:5.48|P-value:2.84E-5 ID:SGTC_894|Compound:0960-0238|FD-Score:37.60|P-value:2.41E-169 ID:SGTC_903|Compound:1134-0042|FD-Score:6.16|P-value:2.99E-6 ID:SGTC_926|Compound:2268-1401|FD-Score:4.46|P-value:5.24E-4 ID:SGTC_932|Compound:2857-0803|FD-Score:4.38|P-value:6.51E-4 ID:SGTC_943|Compound:3253-1379|FD-Score:4.30|P-value:7.95E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.71|P-value:1.36E-5 ID:SGTC_985|Compound:1493-0307|FD-Score:4.53|P-value:4.36E-4 ID:SGTC_993|Compound:3909-8757|FD-Score:7.42|P-value:2.42E-8 ID:SGTC_1026|Compound:k007-1105|FD-Score:16.70|P-value:6.54E-35 ID:SGTC_1060|Compound:3448-7350|FD-Score:4.91|P-value:1.54E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:18.30|P-value:1.31E-41 ID:SGTC_1119|Compound:parthenolide|FD-Score:6.20|P-value:2.54E-6 ID:SGTC_1131|Compound:3454-3128|FD-Score:6.09|P-value:3.70E-6 ID:SGTC_1170|Compound:0310-0127|FD-Score:5.54|P-value:2.29E-5 ID:SGTC_1237|Compound:0330-0133|FD-Score:10.60|P-value:3.83E-15 ID:SGTC_1239|Compound:0337-0584|FD-Score:5.70|P-value:1.40E-5 ID:SGTC_1250|Compound:0485-0349|FD-Score:13.90|P-value:9.76E-25 ID:SGTC_1253|Compound:0550-0034|FD-Score:4.97|P-value:1.28E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:10.10|P-value:4.10E-14 ID:SGTC_1268|Compound:0828-0275|FD-Score:14.10|P-value:1.04E-25 ID:SGTC_1287|Compound:0971-0001|FD-Score:5.88|P-value:7.67E-6 ID:SGTC_1327|Compound:1436-0082|FD-Score:10.00|P-value:8.06E-14 ID:SGTC_1355|Compound:1499-0035|FD-Score:4.35|P-value:7.01E-4 ID:SGTC_1367|Compound:1812-0510|FD-Score:9.57|P-value:9.23E-13 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:6.27|P-value:1.97E-6 ID:SGTC_1422|Compound:4031-0024|FD-Score:4.37|P-value:6.62E-4 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:4.41|P-value:6.03E-4 ID:SGTC_1643|Compound:st009866|FD-Score:5.48|P-value:2.83E-5 ID:SGTC_1674|Compound:st016616|FD-Score:4.62|P-value:3.46E-4 ID:SGTC_1724|Compound:st037281|FD-Score:33.20|P-value:1.03E-132 ID:SGTC_1726|Compound:st035556|FD-Score:5.24|P-value:5.89E-5 ID:SGTC_1732|Compound:st034308|FD-Score:4.21|P-value:9.80E-4 ID:SGTC_1743|Compound:st037606|FD-Score:26.80|P-value:8.77E-87 ID:SGTC_1766|Compound:st045414|FD-Score:5.84|P-value:8.87E-6 ID:SGTC_1772|Compound:st048439|FD-Score:23.10|P-value:1.73E-65 ID:SGTC_1780|Compound:st038448|FD-Score:11.20|P-value:9.74E-17 ID:SGTC_1870|Compound:st057514|FD-Score:10.90|P-value:6.04E-16 ID:SGTC_1909|Compound:st060837|FD-Score:4.84|P-value:1.89E-4 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:4.80|P-value:2.11E-4 ID:SGTC_1927|Compound:st060202|FD-Score:6.45|P-value:1.04E-6 ID:SGTC_1936|Compound:st074407|FD-Score:4.39|P-value:6.32E-4 ID:SGTC_1955|Compound:wogonin|FD-Score:9.64|P-value:6.44E-13 ID:SGTC_1970|Compound:st070122|FD-Score:7.22|P-value:5.46E-8 ID:SGTC_1975|Compound:st070967|FD-Score:5.95|P-value:6.12E-6 ID:SGTC_1982|Compound:st072467|FD-Score:4.32|P-value:7.55E-4 ID:SGTC_1994|Compound:st072947|FD-Score:30.60|P-value:4.92E-113 ID:SGTC_2025|Compound:5147754|FD-Score:14.30|P-value:2.49E-26 ID:SGTC_2041|Compound:5107442|FD-Score:5.27|P-value:5.34E-5 ID:SGTC_2077|Compound:5212015|FD-Score:7.63|P-value:9.91E-9 ID:SGTC_2122|Compound:5258151|FD-Score:8.93|P-value:2.53E-11 ID:SGTC_2124|Compound:5246320|FD-Score:5.48|P-value:2.80E-5 ID:SGTC_2189|Compound:6047310|FD-Score:4.40|P-value:6.11E-4 ID:SGTC_2296|Compound:7971656|FD-Score:6.84|P-value:2.43E-7 ID:SGTC_2316|Compound:5844804|FD-Score:8.49|P-value:2.13E-10 ID:SGTC_2325|Compound:6158266|FD-Score:6.03|P-value:4.57E-6 ID:SGTC_2356|Compound:9061756|FD-Score:4.54|P-value:4.23E-4 ID:SGTC_2436|Compound:5633522|FD-Score:5.04|P-value:1.06E-4 ID:SGTC_2482|Compound:5981709|FD-Score:5.17|P-value:7.30E-5 ID:SGTC_2526|Compound:patulin|FD-Score:7.32|P-value:3.66E-8 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.00|P-value:7.40E-22 ID:SGTC_2584|Compound:androsterone|FD-Score:-4.70|P-value:2.58E-4 ID:SGTC_2588|Compound:indole-3-carbinol|FD-Score:-4.32|P-value:6.94E-4 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.46|P-value:5.20E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:6.13|P-value:3.32E-6 ID:SGTC_2666|Compound:tannic acid|FD-Score:6.24|P-value:2.20E-6 ID:SGTC_2689|Compound:tacrolimus|FD-Score:6.67|P-value:4.57E-7 ID:SGTC_2701|Compound:st077767|FD-Score:4.40|P-value:6.06E-4 ID:SGTC_2708|Compound:st078559|FD-Score:-4.48|P-value:4.66E-4 ID:SGTC_2716|Compound:st080858|FD-Score:-6.72|P-value:3.51E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:6.87|P-value:2.14E-7 ID:SGTC_2784|Compound:7567673|FD-Score:10.90|P-value:5.00E-16 ID:SGTC_2805|Compound:7950783|FD-Score:14.10|P-value:1.35E-25 ID:SGTC_2810|Compound:7959871|FD-Score:6.57|P-value:6.76E-7 ID:SGTC_2824|Compound:7998404|FD-Score:5.42|P-value:3.32E-5 ID:SGTC_2867|Compound:9039098|FD-Score:5.12|P-value:8.26E-5 ID:SGTC_2890|Compound:9046729|FD-Score:6.04|P-value:4.44E-6 ID:SGTC_2900|Compound:5328528|FD-Score:5.34|P-value:4.31E-5 ID:SGTC_2912|Compound:7964298|FD-Score:5.23|P-value:5.96E-5 ID:SGTC_3059|Compound:1327-0034|FD-Score:4.27|P-value:8.42E-4 ID:SGTC_3062|Compound:9077494|FD-Score:-5.19|P-value:6.28E-5 ID:SGTC_3068|Compound:9116768|FD-Score:6.12|P-value:3.33E-6 ID:SGTC_3102|Compound:9121669|FD-Score:6.50|P-value:8.56E-7 ID:SGTC_3110|Compound:9122132|FD-Score:5.01|P-value:1.16E-4 ID:SGTC_3112|Compound:9123419|FD-Score:4.95|P-value:1.36E-4 ID:SGTC_3115|Compound:9123671|FD-Score:4.69|P-value:2.86E-4 ID:SGTC_3122|Compound:9126309|FD-Score:4.51|P-value:4.65E-4 ID:SGTC_3141|Compound:9094609|FD-Score:9.55|P-value:1.03E-12 ID:SGTC_3142|Compound:9086498|FD-Score:7.45|P-value:2.12E-8 ID:SGTC_3189|Compound:9110682|FD-Score:8.04|P-value:1.68E-9 ID:SGTC_3197|Compound:9113331|FD-Score:18.50|P-value:9.25E-43 ID:SGTC_3200|Compound:9114385|FD-Score:15.70|P-value:2.40E-31 ID:SGTC_3203|Compound:9113543|FD-Score:7.34|P-value:3.38E-8 ID:SGTC_3219|Compound:9131112|FD-Score:-4.38|P-value:6.04E-4 ID:SGTC_3232|Compound:9132874|FD-Score:5.57|P-value:2.08E-5 ID:SGTC_3296|Compound:9122258|FD-Score:4.49|P-value:4.80E-4 ID:SGTC_3307|Compound:9126885|FD-Score:7.73|P-value:6.50E-9 ID:SGTC_3|Compound:0833-0587|FD-Score:6.41|P-value:1.20E-6 ID:SGTC_41|Compound:0478-0632|FD-Score:11.80|P-value:2.48E-18 ID:SGTC_43|Compound:0570-0105|FD-Score:14.70|P-value:1.54E-27 ID:SGTC_46|Compound:0329-0187a|FD-Score:7.38|P-value:2.81E-8 ID:SGTC_58|Compound:0957-0393|FD-Score:7.81|P-value:4.51E-9 ID:SGTC_77|Compound:0828-0286|FD-Score:11.00|P-value:2.88E-16 ID:SGTC_89|Compound:0302-0250|FD-Score:5.18|P-value:6.97E-5 ID:SGTC_103|Compound:0844-0104|FD-Score:5.38|P-value:3.81E-5 ID:SGTC_106|Compound:0092-0003|FD-Score:10.00|P-value:8.99E-14 ID:SGTC_109|Compound:0132-0036|FD-Score:4.32|P-value:7.55E-4 ID:SGTC_126|Compound:0417-1624|FD-Score:16.00|P-value:2.73E-32 ID:SGTC_131|Compound:0141-0277|FD-Score:4.58|P-value:3.83E-4 ID:SGTC_132|Compound:0417-1715|FD-Score:5.67|P-value:1.54E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:10.50|P-value:4.56E-15 ID:SGTC_145|Compound:3737-0113|FD-Score:8.64|P-value:1.03E-10 ID:SGTC_153|Compound:4077-0274|FD-Score:4.61|P-value:3.53E-4 ID:SGTC_156|Compound:3474-0145|FD-Score:12.40|P-value:4.42E-20 ID:SGTC_157|Compound:1348-1695|FD-Score:13.60|P-value:9.14E-24 ID:SGTC_161|Compound:4065-0411|FD-Score:8.84|P-value:3.94E-11 ID:SGTC_191|Compound:3914-0123|FD-Score:5.06|P-value:9.90E-5 ID:SGTC_208|Compound:k072-0098|FD-Score:11.10|P-value:1.32E-16 ID:SGTC_211|Compound:3455-0679|FD-Score:6.14|P-value:3.16E-6 ID:SGTC_263|Compound:alizarin|FD-Score:8.26|P-value:6.12E-10 ID:SGTC_290|Compound:2043-6722|FD-Score:5.06|P-value:9.99E-5 ID:SGTC_311|Compound:1315-0136|FD-Score:6.77|P-value:3.20E-7 ID:SGTC_330|Compound:1488-0319|FD-Score:5.44|P-value:3.15E-5 ID:SGTC_342|Compound:k048-0088|FD-Score:5.69|P-value:1.43E-5 ID:SGTC_349|Compound:k015-0014|FD-Score:6.08|P-value:3.83E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:5.17|P-value:7.27E-5 ID:SGTC_352|Compound:k048-0007|FD-Score:5.36|P-value:4.09E-5 ID:SGTC_354|Compound:2783-3500|FD-Score:4.93|P-value:1.44E-4 ID:SGTC_356|Compound:1634-0012|FD-Score:9.85|P-value:2.13E-13 ID:SGTC_362|Compound:0310-0100|FD-Score:5.76|P-value:1.13E-5 ID:SGTC_363|Compound:0455-0021|FD-Score:5.93|P-value:6.44E-6 ID:SGTC_372|Compound:0155-0182|FD-Score:-4.83|P-value:1.79E-4 ID:SGTC_389|Compound:tpck|FD-Score:4.48|P-value:4.97E-4 ID:SGTC_394|Compound:menadione|FD-Score:6.79|P-value:2.91E-7 ID:SGTC_444|Compound:curcumin|FD-Score:5.61|P-value:1.84E-5 ID:SGTC_483|Compound:fpl-64176|FD-Score:6.16|P-value:2.99E-6 ID:SGTC_524|Compound:r073-0010|FD-Score:13.50|P-value:1.43E-23 ID:SGTC_525|Compound:k781-2675|FD-Score:38.70|P-value:2.50E-179 ID:SGTC_538|Compound:2922-0838|FD-Score:5.27|P-value:5.38E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:6.17|P-value:2.84E-6 ID:SGTC_543|Compound:3844-1095|FD-Score:4.43|P-value:5.66E-4 ID:SGTC_550|Compound:4123-0385|FD-Score:4.39|P-value:6.20E-4 ID:SGTC_557|Compound:1315-0110|FD-Score:6.11|P-value:3.49E-6 ID:SGTC_572|Compound:0960-0087|FD-Score:9.72|P-value:4.19E-13 ID:SGTC_576|Compound:1073-0113|FD-Score:12.10|P-value:3.32E-19 ID:SGTC_586|Compound:0957-0265|FD-Score:9.79|P-value:2.96E-13 ID:SGTC_590|Compound:k048-0076|FD-Score:4.59|P-value:3.67E-4 ID:SGTC_595|Compound:3909-8003|FD-Score:4.50|P-value:4.66E-4 ID:SGTC_619|Compound:1652-1634|FD-Score:5.10|P-value:8.87E-5 ID:SGTC_647|Compound:0140-0236|FD-Score:8.91|P-value:2.73E-11 ID:SGTC_657|Compound:3534-0529|FD-Score:6.03|P-value:4.67E-6 ID:SGTC_667|Compound:1498-1044|FD-Score:5.32|P-value:4.56E-5 ID:SGTC_690|Compound:glyoxal|FD-Score:5.45|P-value:3.10E-5 ID:SGTC_699|Compound:0375-0592|FD-Score:9.89|P-value:1.67E-13 ID:SGTC_733|Compound:4069-0007|FD-Score:4.87|P-value:1.70E-4 ID:SGTC_734|Compound:2023-0417|FD-Score:4.35|P-value:6.89E-4 ID:SGTC_741|Compound:4582-0002|FD-Score:5.19|P-value:6.82E-5 ID:SGTC_756|Compound:0508-1999|FD-Score:4.37|P-value:6.59E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:12.60|P-value:8.93E-21 ID:SGTC_786|Compound:4544-0069|FD-Score:6.64|P-value:5.23E-7 ID:SGTC_790|Compound:1575-0012|FD-Score:7.00|P-value:1.30E-7 ID:SGTC_805|Compound:3852-0218|FD-Score:4.26|P-value:8.71E-4 ID:SGTC_828|Compound:2074-0507|FD-Score:5.46|P-value:2.94E-5 ID:SGTC_845|Compound:0330-0138|FD-Score:5.23|P-value:6.01E-5 ID:SGTC_848|Compound:0368-0089|FD-Score:6.87|P-value:2.16E-7 ID:SGTC_855|Compound:0428-0020|FD-Score:11.50|P-value:1.58E-17 ID:SGTC_878|Compound:0828-0289|FD-Score:11.90|P-value:7.54E-19 ID:SGTC_879|Compound:0831-1030|FD-Score:4.70|P-value:2.74E-4 ID:SGTC_893|Compound:0958-0369|FD-Score:5.48|P-value:2.84E-5 ID:SGTC_894|Compound:0960-0238|FD-Score:37.60|P-value:2.41E-169 ID:SGTC_903|Compound:1134-0042|FD-Score:6.16|P-value:2.99E-6 ID:SGTC_926|Compound:2268-1401|FD-Score:4.46|P-value:5.24E-4 ID:SGTC_932|Compound:2857-0803|FD-Score:4.38|P-value:6.51E-4 ID:SGTC_943|Compound:3253-1379|FD-Score:4.30|P-value:7.95E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.71|P-value:1.36E-5 ID:SGTC_985|Compound:1493-0307|FD-Score:4.53|P-value:4.36E-4 ID:SGTC_993|Compound:3909-8757|FD-Score:7.42|P-value:2.42E-8 ID:SGTC_1026|Compound:k007-1105|FD-Score:16.70|P-value:6.54E-35 ID:SGTC_1060|Compound:3448-7350|FD-Score:4.91|P-value:1.54E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:18.30|P-value:1.31E-41 ID:SGTC_1119|Compound:parthenolide|FD-Score:6.20|P-value:2.54E-6 ID:SGTC_1131|Compound:3454-3128|FD-Score:6.09|P-value:3.70E-6 ID:SGTC_1170|Compound:0310-0127|FD-Score:5.54|P-value:2.29E-5 ID:SGTC_1237|Compound:0330-0133|FD-Score:10.60|P-value:3.83E-15 ID:SGTC_1239|Compound:0337-0584|FD-Score:5.70|P-value:1.40E-5 ID:SGTC_1250|Compound:0485-0349|FD-Score:13.90|P-value:9.76E-25 ID:SGTC_1253|Compound:0550-0034|FD-Score:4.97|P-value:1.28E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:10.10|P-value:4.10E-14 ID:SGTC_1268|Compound:0828-0275|FD-Score:14.10|P-value:1.04E-25 ID:SGTC_1287|Compound:0971-0001|FD-Score:5.88|P-value:7.67E-6 ID:SGTC_1327|Compound:1436-0082|FD-Score:10.00|P-value:8.06E-14 ID:SGTC_1355|Compound:1499-0035|FD-Score:4.35|P-value:7.01E-4 ID:SGTC_1367|Compound:1812-0510|FD-Score:9.57|P-value:9.23E-13 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:6.27|P-value:1.97E-6 ID:SGTC_1422|Compound:4031-0024|FD-Score:4.37|P-value:6.62E-4 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:4.41|P-value:6.03E-4 ID:SGTC_1643|Compound:st009866|FD-Score:5.48|P-value:2.83E-5 ID:SGTC_1674|Compound:st016616|FD-Score:4.62|P-value:3.46E-4 ID:SGTC_1724|Compound:st037281|FD-Score:33.20|P-value:1.03E-132 ID:SGTC_1726|Compound:st035556|FD-Score:5.24|P-value:5.89E-5 ID:SGTC_1732|Compound:st034308|FD-Score:4.21|P-value:9.80E-4 ID:SGTC_1743|Compound:st037606|FD-Score:26.80|P-value:8.77E-87 ID:SGTC_1766|Compound:st045414|FD-Score:5.84|P-value:8.87E-6 ID:SGTC_1772|Compound:st048439|FD-Score:23.10|P-value:1.73E-65 ID:SGTC_1780|Compound:st038448|FD-Score:11.20|P-value:9.74E-17 ID:SGTC_1870|Compound:st057514|FD-Score:10.90|P-value:6.04E-16 ID:SGTC_1909|Compound:st060837|FD-Score:4.84|P-value:1.89E-4 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:4.80|P-value:2.11E-4 ID:SGTC_1927|Compound:st060202|FD-Score:6.45|P-value:1.04E-6 ID:SGTC_1936|Compound:st074407|FD-Score:4.39|P-value:6.32E-4 ID:SGTC_1955|Compound:wogonin|FD-Score:9.64|P-value:6.44E-13 ID:SGTC_1970|Compound:st070122|FD-Score:7.22|P-value:5.46E-8 ID:SGTC_1975|Compound:st070967|FD-Score:5.95|P-value:6.12E-6 ID:SGTC_1982|Compound:st072467|FD-Score:4.32|P-value:7.55E-4 ID:SGTC_1994|Compound:st072947|FD-Score:30.60|P-value:4.92E-113 ID:SGTC_2025|Compound:5147754|FD-Score:14.30|P-value:2.49E-26 ID:SGTC_2041|Compound:5107442|FD-Score:5.27|P-value:5.34E-5 ID:SGTC_2077|Compound:5212015|FD-Score:7.63|P-value:9.91E-9 ID:SGTC_2122|Compound:5258151|FD-Score:8.93|P-value:2.53E-11 ID:SGTC_2124|Compound:5246320|FD-Score:5.48|P-value:2.80E-5 ID:SGTC_2189|Compound:6047310|FD-Score:4.40|P-value:6.11E-4 ID:SGTC_2296|Compound:7971656|FD-Score:6.84|P-value:2.43E-7 ID:SGTC_2316|Compound:5844804|FD-Score:8.49|P-value:2.13E-10 ID:SGTC_2325|Compound:6158266|FD-Score:6.03|P-value:4.57E-6 ID:SGTC_2356|Compound:9061756|FD-Score:4.54|P-value:4.23E-4 ID:SGTC_2436|Compound:5633522|FD-Score:5.04|P-value:1.06E-4 ID:SGTC_2482|Compound:5981709|FD-Score:5.17|P-value:7.30E-5 ID:SGTC_2526|Compound:patulin|FD-Score:7.32|P-value:3.66E-8 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.00|P-value:7.40E-22 ID:SGTC_2584|Compound:androsterone|FD-Score:-4.70|P-value:2.58E-4 ID:SGTC_2588|Compound:indole-3-carbinol|FD-Score:-4.32|P-value:6.94E-4 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.46|P-value:5.20E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:6.13|P-value:3.32E-6 ID:SGTC_2666|Compound:tannic acid|FD-Score:6.24|P-value:2.20E-6 ID:SGTC_2689|Compound:tacrolimus|FD-Score:6.67|P-value:4.57E-7 ID:SGTC_2701|Compound:st077767|FD-Score:4.40|P-value:6.06E-4 ID:SGTC_2708|Compound:st078559|FD-Score:-4.48|P-value:4.66E-4 ID:SGTC_2716|Compound:st080858|FD-Score:-6.72|P-value:3.51E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:6.87|P-value:2.14E-7 ID:SGTC_2784|Compound:7567673|FD-Score:10.90|P-value:5.00E-16 ID:SGTC_2805|Compound:7950783|FD-Score:14.10|P-value:1.35E-25 ID:SGTC_2810|Compound:7959871|FD-Score:6.57|P-value:6.76E-7 ID:SGTC_2824|Compound:7998404|FD-Score:5.42|P-value:3.32E-5 ID:SGTC_2867|Compound:9039098|FD-Score:5.12|P-value:8.26E-5 ID:SGTC_2890|Compound:9046729|FD-Score:6.04|P-value:4.44E-6 ID:SGTC_2900|Compound:5328528|FD-Score:5.34|P-value:4.31E-5 ID:SGTC_2912|Compound:7964298|FD-Score:5.23|P-value:5.96E-5 ID:SGTC_3059|Compound:1327-0034|FD-Score:4.27|P-value:8.42E-4 ID:SGTC_3062|Compound:9077494|FD-Score:-5.19|P-value:6.28E-5 ID:SGTC_3068|Compound:9116768|FD-Score:6.12|P-value:3.33E-6 ID:SGTC_3102|Compound:9121669|FD-Score:6.50|P-value:8.56E-7 ID:SGTC_3110|Compound:9122132|FD-Score:5.01|P-value:1.16E-4 ID:SGTC_3112|Compound:9123419|FD-Score:4.95|P-value:1.36E-4 ID:SGTC_3115|Compound:9123671|FD-Score:4.69|P-value:2.86E-4 ID:SGTC_3122|Compound:9126309|FD-Score:4.51|P-value:4.65E-4 ID:SGTC_3141|Compound:9094609|FD-Score:9.55|P-value:1.03E-12 ID:SGTC_3142|Compound:9086498|FD-Score:7.45|P-value:2.12E-8 ID:SGTC_3189|Compound:9110682|FD-Score:8.04|P-value:1.68E-9 ID:SGTC_3197|Compound:9113331|FD-Score:18.50|P-value:9.25E-43 ID:SGTC_3200|Compound:9114385|FD-Score:15.70|P-value:2.40E-31 ID:SGTC_3203|Compound:9113543|FD-Score:7.34|P-value:3.38E-8 ID:SGTC_3219|Compound:9131112|FD-Score:-4.38|P-value:6.04E-4 ID:SGTC_3232|Compound:9132874|FD-Score:5.57|P-value:2.08E-5 ID:SGTC_3296|Compound:9122258|FD-Score:4.49|P-value:4.80E-4 ID:SGTC_3307|Compound:9126885|FD-Score:7.73|P-value:6.50E-9

Top fitness defect scores for YDL195W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_525 k781-2675 38.70 26.7 µM 2.50E-179 redox potentiating 1 0 17.70
2 SGTC_894 0960-0238 37.60 55.9 µM 2.41E-169 1 0 28.70
3 SGTC_1724 st037281 33.20 8.3 µM 1.03E-132 1 1.68E-242 24.50
4 SGTC_1994 st072947 30.60 40.9 µM 4.92E-113 1 2.70E-206 24.80
5 SGTC_1743 st037606 26.80 46.4 µM 8.77E-87 2 5.34E-158 21.50
6 SGTC_1772 st048439 23.10 82.2 µM 1.73E-65 1 7.85E-119 9.29
7 SGTC_3197 9113331 18.50 49.5 µM 9.25E-43 2 4.77E-77 9.74
8 SGTC_1104 tacrolimus 18.30 29.8 µM 1.31E-41 3 6.23E-75 10.20
9 SGTC_1026 k007-1105 16.70 30.6 µM 6.54E-35 ERAD & cell cycle 2 1.26E-62 4.23
10 SGTC_126 0417-1624 16.00 672.5 µM 2.73E-32 DNA intercalators 1 8.16E-58 7.73
11 SGTC_3200 9114385 15.70 49.5 µM 2.40E-31 2 4.42E-56 9.50
12 SGTC_43 0570-0105 14.70 72.5 µM 1.54E-27 ERG2 1 4.35E-49 6.99
13 SGTC_2025 5147754 14.30 141.0 µM 2.49E-26 2 7.16E-47 7.94
14 SGTC_1268 0828-0275 14.10 2.5 µM 1.04E-25 1 9.91E-46 4.76
15 SGTC_2805 7950783 14.10 58.4 µM 1.35E-25 1 1.59E-45 7.06
16 SGTC_1250 0485-0349 13.90 40.2 µM 9.76E-25 1 6.00E-44 8.18
17 SGTC_157 1348-1695 13.60 65.8 µM 9.14E-24 iron homeostasis 1 3.63E-42 2.96
18 SGTC_524 r073-0010 13.50 27.8 µM 1.43E-23 1 8.24E-42 3.70
19 SGTC_2582 agaric acid 13.00 100.0 µM 7.40E-22 redox potentiating 4 1.15E-38 2.23
20 SGTC_764 1951-2361 12.60 146.0 µM 8.93E-21 1 1.11E-36 3.96

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.443 1.55E-161 YLR208W SEC13 het Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress
0.171 2.15E-23 YLR268W SEC22 hom R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog
0.153 6.19E-19 YER083C GET2 hom Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division
0.141 3.20E-16 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.129 6.06E-14 YDL196W_d YDL196W_d het Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame is located in promoter region of essential gene SEC31
0.126 3.29E-13 YDR010C_d YDR010C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.125 3.48E-13 YGR115C_d YGR115C_d het Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified and essential ORF SPT6/YGR115C
0.122 1.31E-12 YBR091C TIM12 het Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
0.113 4.42E-11 YGL020C GET1 hom Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
0.110 1.70E-10 YOL018C TLG2 hom Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)
0.110 1.56E-10 YDR269C_d YDR269C_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.110 2.02E-10 YIL109C SEC24 het Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb2p and Sfb3p
0.107 6.04E-10 YER084W_p YER084W_p hom Protein of unknown function; expressed at both mRNA and protein levels
0.104 1.42E-9 YDR108W TRS85 hom Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
0.104 1.46E-9 YKR035C_d OPI8_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene DID2/YKR035W-A