YDL226C / GCS1

ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p

Zygosity: Homozygous strain
fixedexpanded
Profile for YDL226C / GCS1

Click on Significant Values for Screen Details ID:SGTC_31|Compound:0508-1974|FD-Score:-4.17|P-value:2.22E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:15.50|P-value:7.29E-39 ID:SGTC_58|Compound:0957-0393|FD-Score:-8.35|P-value:1.07E-12 ID:SGTC_59|Compound:0330-0160|FD-Score:-3.89|P-value:5.21E-4 ID:SGTC_67|Compound:0335-0847|FD-Score:6.94|P-value:2.87E-9 ID:SGTC_70|Compound:0141-0289|FD-Score:18.50|P-value:1.14E-54 ID:SGTC_75|Compound:0159-0059|FD-Score:4.66|P-value:4.65E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:5.68|P-value:9.56E-7 ID:SGTC_103|Compound:0844-0104|FD-Score:5.65|P-value:1.08E-6 ID:SGTC_115|Compound:0527-0192|FD-Score:-3.82|P-value:6.43E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:3.84|P-value:6.48E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:-7.12|P-value:1.05E-9 ID:SGTC_119|Compound:0121-0043|FD-Score:5.19|P-value:6.92E-6 ID:SGTC_124|Compound:0136-0217|FD-Score:8.35|P-value:1.23E-12 ID:SGTC_137|Compound:0438-0332|FD-Score:4.90|P-value:2.03E-5 ID:SGTC_145|Compound:3737-0113|FD-Score:6.33|P-value:5.62E-8 ID:SGTC_163|Compound:1327-0036|FD-Score:-4.69|P-value:3.84E-5 ID:SGTC_178|Compound:4092-0806|FD-Score:33.10|P-value:8.17E-171 ID:SGTC_183|Compound:3914-0051|FD-Score:-5.74|P-value:6.89E-7 ID:SGTC_201|Compound:4262-0159|FD-Score:17.10|P-value:7.35E-47 ID:SGTC_207|Compound:4185-0010|FD-Score:14.80|P-value:1.46E-35 ID:SGTC_208|Compound:k072-0098|FD-Score:10.40|P-value:1.03E-18 ID:SGTC_217|Compound:ketoconazole|FD-Score:5.40|P-value:3.02E-6 ID:SGTC_218|Compound:alverine citrate|FD-Score:27.70|P-value:3.37E-120 ID:SGTC_245|Compound:methotrexate|FD-Score:3.77|P-value:8.06E-4 ID:SGTC_252|Compound:miconazole|FD-Score:10.40|P-value:1.63E-18 ID:SGTC_253|Compound:dyclonine|FD-Score:13.00|P-value:6.68E-28 ID:SGTC_254|Compound:nsc-64875|FD-Score:29.50|P-value:4.00E-136 ID:SGTC_256|Compound:clotrimazole|FD-Score:6.97|P-value:2.52E-9 ID:SGTC_258|Compound:haloperidol|FD-Score:30.60|P-value:8.41E-146 ID:SGTC_262|Compound:fenpropimorph|FD-Score:19.90|P-value:5.03E-63 ID:SGTC_263|Compound:alizarin|FD-Score:10.40|P-value:1.81E-18 ID:SGTC_264|Compound:promethazine|FD-Score:4.60|P-value:5.75E-5 ID:SGTC_278|Compound:4092-0821|FD-Score:21.70|P-value:3.07E-74 ID:SGTC_288|Compound:1315-0019|FD-Score:7.01|P-value:2.07E-9 ID:SGTC_294|Compound:k038-0071|FD-Score:5.56|P-value:1.55E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-6.59|P-value:1.48E-8 ID:SGTC_308|Compound:4092-1169|FD-Score:14.60|P-value:4.99E-35 ID:SGTC_310|Compound:1273-0058|FD-Score:-10.50|P-value:4.96E-19 ID:SGTC_312|Compound:4092-0653|FD-Score:14.50|P-value:2.44E-34 ID:SGTC_314|Compound:1671-0008|FD-Score:-5.88|P-value:3.66E-7 ID:SGTC_320|Compound:4092-0846|FD-Score:14.00|P-value:3.59E-32 ID:SGTC_340|Compound:k038-0059|FD-Score:3.69|P-value:9.96E-4 ID:SGTC_346|Compound:4513-0042|FD-Score:4.07|P-value:3.30E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:3.90|P-value:5.37E-4 ID:SGTC_352|Compound:k048-0007|FD-Score:10.70|P-value:9.97E-20 ID:SGTC_367|Compound:0335-0881|FD-Score:14.40|P-value:3.80E-34 ID:SGTC_373|Compound:0844-0104|FD-Score:14.40|P-value:4.91E-34 ID:SGTC_374|Compound:0880-0231|FD-Score:16.40|P-value:1.42E-43 ID:SGTC_384|Compound:k007-0144|FD-Score:22.10|P-value:6.35E-77 ID:SGTC_426|Compound:0988-0037|FD-Score:4.64|P-value:4.97E-5 ID:SGTC_513|Compound:4245-1575|FD-Score:-5.27|P-value:4.64E-6 ID:SGTC_514|Compound:4466-0038|FD-Score:3.74|P-value:8.66E-4 ID:SGTC_515|Compound:4092-1064|FD-Score:9.27|P-value:3.59E-15 ID:SGTC_524|Compound:r073-0010|FD-Score:4.87|P-value:2.25E-5 ID:SGTC_553|Compound:k007-0256|FD-Score:8.44|P-value:7.35E-13 ID:SGTC_568|Compound:1193-0097|FD-Score:12.40|P-value:9.77E-26 ID:SGTC_577|Compound:r071-0003|FD-Score:19.40|P-value:8.92E-60 ID:SGTC_605|Compound:1315-0399|FD-Score:3.82|P-value:6.82E-4 ID:SGTC_617|Compound:3770-0098|FD-Score:-3.85|P-value:5.87E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:15.20|P-value:1.91E-37 ID:SGTC_642|Compound:0335-0876|FD-Score:10.20|P-value:6.12E-18 ID:SGTC_646|Compound:4092-0839|FD-Score:13.90|P-value:7.19E-32 ID:SGTC_649|Compound:1123-0311|FD-Score:15.60|P-value:1.18E-39 ID:SGTC_658|Compound:3253-0951|FD-Score:10.80|P-value:7.97E-20 ID:SGTC_660|Compound:4031-1742|FD-Score:10.20|P-value:3.95E-18 ID:SGTC_669|Compound:0108-0021|FD-Score:12.70|P-value:1.14E-26 ID:SGTC_688|Compound:0527-0193|FD-Score:9.05|P-value:1.54E-14 ID:SGTC_689|Compound:0833-0039|FD-Score:12.60|P-value:1.59E-26 ID:SGTC_690|Compound:glyoxal|FD-Score:-4.71|P-value:3.63E-5 ID:SGTC_699|Compound:0375-0592|FD-Score:7.11|P-value:1.25E-9 ID:SGTC_706|Compound:4262-0057|FD-Score:12.50|P-value:6.02E-26 ID:SGTC_710|Compound:3448-4187|FD-Score:10.80|P-value:6.33E-20 ID:SGTC_733|Compound:4069-0007|FD-Score:9.06|P-value:1.43E-14 ID:SGTC_768|Compound:0384-0033|FD-Score:28.00|P-value:1.54E-122 ID:SGTC_778|Compound:3456-2434|FD-Score:3.80|P-value:7.20E-4 ID:SGTC_779|Compound:1360-0071|FD-Score:9.99|P-value:2.64E-17 ID:SGTC_788|Compound:1182-0090|FD-Score:9.90|P-value:5.05E-17 ID:SGTC_794|Compound:k038-0031|FD-Score:8.45|P-value:6.91E-13 ID:SGTC_809|Compound:3998-0021|FD-Score:5.58|P-value:1.43E-6 ID:SGTC_813|Compound:k007-0158|FD-Score:13.60|P-value:1.64E-30 ID:SGTC_834|Compound:0312-0008|FD-Score:10.40|P-value:1.79E-18 ID:SGTC_837|Compound:0091-0265|FD-Score:7.60|P-value:9.27E-11 ID:SGTC_846|Compound:0335-0850|FD-Score:8.10|P-value:5.45E-12 ID:SGTC_868|Compound:0527-0199|FD-Score:27.70|P-value:2.84E-120 ID:SGTC_875|Compound:0709-0210|FD-Score:37.70|P-value:6.60E-220 ID:SGTC_887|Compound:0885-0007|FD-Score:16.30|P-value:9.23E-43 ID:SGTC_922|Compound:1866-0035|FD-Score:-4.21|P-value:1.93E-4 ID:SGTC_941|Compound:3237-0776|FD-Score:4.07|P-value:3.26E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:6.78|P-value:6.61E-9 ID:SGTC_963|Compound:1269-2853|FD-Score:3.96|P-value:4.55E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.02|P-value:1.30E-5 ID:SGTC_977|Compound:1348-1378|FD-Score:4.25|P-value:1.85E-4 ID:SGTC_978|Compound:1416-0512|FD-Score:5.03|P-value:1.26E-5 ID:SGTC_1005|Compound:4092-0690|FD-Score:17.10|P-value:7.75E-47 ID:SGTC_1019|Compound:4262-0212|FD-Score:12.90|P-value:1.79E-27 ID:SGTC_1026|Compound:k007-1105|FD-Score:9.66|P-value:2.64E-16 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.65|P-value:2.83E-16 ID:SGTC_1076|Compound:itraconazole|FD-Score:3.97|P-value:4.44E-4 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.65|P-value:4.86E-5 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:11.50|P-value:2.73E-22 ID:SGTC_1123|Compound:mangostin|FD-Score:5.17|P-value:7.25E-6 ID:SGTC_1126|Compound:isoteolin|FD-Score:4.42|P-value:1.07E-4 ID:SGTC_1156|Compound:4092-0367|FD-Score:4.68|P-value:4.39E-5 ID:SGTC_1160|Compound:4092-0570|FD-Score:12.80|P-value:3.07E-27 ID:SGTC_1161|Compound:k007-0610|FD-Score:4.72|P-value:3.81E-5 ID:SGTC_1191|Compound:1487-1166|FD-Score:6.06|P-value:1.84E-7 ID:SGTC_1205|Compound:4161-2785|FD-Score:-6.83|P-value:4.54E-9 ID:SGTC_1230|Compound:0170-0365|FD-Score:10.20|P-value:5.25E-18 ID:SGTC_1281|Compound:0884-0031|FD-Score:7.19|P-value:8.01E-10 ID:SGTC_1286|Compound:0929-0070|FD-Score:4.36|P-value:1.29E-4 ID:SGTC_1305|Compound:1181-0477|FD-Score:3.75|P-value:8.54E-4 ID:SGTC_1306|Compound:1185-0270|FD-Score:14.20|P-value:3.21E-33 ID:SGTC_1308|Compound:1187-1617|FD-Score:20.70|P-value:7.99E-68 ID:SGTC_1313|Compound:1220-0047|FD-Score:11.50|P-value:2.88E-22 ID:SGTC_1326|Compound:1431-2094|FD-Score:3.96|P-value:4.59E-4 ID:SGTC_1341|Compound:1486-1360|FD-Score:4.11|P-value:2.84E-4 ID:SGTC_1356|Compound:1502-0781|FD-Score:6.63|P-value:1.32E-8 ID:SGTC_1422|Compound:4031-0024|FD-Score:8.91|P-value:3.85E-14 ID:SGTC_1435|Compound:4092-0789|FD-Score:9.04|P-value:1.72E-14 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.91|P-value:1.94E-5 ID:SGTC_1454|Compound:4239-0054|FD-Score:3.98|P-value:4.24E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:18.20|P-value:4.59E-53 ID:SGTC_1460|Compound:k062-0059|FD-Score:4.62|P-value:5.44E-5 ID:SGTC_1461|Compound:k072-0203|FD-Score:-4.43|P-value:9.51E-5 ID:SGTC_1475|Compound:4092-1048|FD-Score:15.80|P-value:2.19E-40 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:4.78|P-value:3.05E-5 ID:SGTC_1581|Compound:himbacine|FD-Score:6.07|P-value:1.79E-7 ID:SGTC_1619|Compound:st003326|FD-Score:-3.91|P-value:5.00E-4 ID:SGTC_1624|Compound:st003710|FD-Score:-3.92|P-value:4.76E-4 ID:SGTC_1658|Compound:st012944|FD-Score:13.50|P-value:7.33E-30 ID:SGTC_1660|Compound:st012960|FD-Score:4.64|P-value:5.11E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:5.81|P-value:5.57E-7 ID:SGTC_1729|Compound:st035615|FD-Score:4.94|P-value:1.74E-5 ID:SGTC_1731|Compound:st035964|FD-Score:5.07|P-value:1.06E-5 ID:SGTC_1741|Compound:st038134|FD-Score:-4.10|P-value:2.79E-4 ID:SGTC_1750|Compound:st081859|FD-Score:40.30|P-value:5.85E-251 ID:SGTC_1775|Compound:st081588|FD-Score:3.76|P-value:8.22E-4 ID:SGTC_1780|Compound:st038448|FD-Score:6.14|P-value:1.33E-7 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:11.70|P-value:5.72E-23 ID:SGTC_1797|Compound:st048695|FD-Score:17.80|P-value:5.27E-51 ID:SGTC_1844|Compound:rapamycin|FD-Score:-6.79|P-value:5.58E-9 ID:SGTC_1884|Compound:5633444|FD-Score:6.37|P-value:4.65E-8 ID:SGTC_1893|Compound:st059353|FD-Score:4.03|P-value:3.71E-4 ID:SGTC_1903|Compound:st060211|FD-Score:3.71|P-value:9.53E-4 ID:SGTC_1904|Compound:st060225|FD-Score:6.15|P-value:1.25E-7 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:13.20|P-value:7.38E-29 ID:SGTC_1941|Compound:st076221|FD-Score:-4.02|P-value:3.54E-4 ID:SGTC_1962|Compound:st076595|FD-Score:6.47|P-value:2.88E-8 ID:SGTC_1999|Compound:st074831|FD-Score:11.40|P-value:4.86E-22 ID:SGTC_2006|Compound:4011487|FD-Score:22.50|P-value:1.01E-79 ID:SGTC_2021|Compound:4019055|FD-Score:4.06|P-value:3.32E-4 ID:SGTC_2028|Compound:5153890|FD-Score:5.15|P-value:7.80E-6 ID:SGTC_2036|Compound:5160441|FD-Score:29.60|P-value:7.26E-137 ID:SGTC_2038|Compound:4100038|FD-Score:23.80|P-value:5.70E-89 ID:SGTC_2046|Compound:4110841|FD-Score:5.14|P-value:8.37E-6 ID:SGTC_2050|Compound:5263056|FD-Score:26.50|P-value:1.27E-109 ID:SGTC_2066|Compound:5222451|FD-Score:4.56|P-value:6.54E-5 ID:SGTC_2111|Compound:5486399|FD-Score:-3.76|P-value:7.58E-4 ID:SGTC_2129|Compound:girgensonine|FD-Score:7.10|P-value:1.30E-9 ID:SGTC_2210|Compound:7115885|FD-Score:5.92|P-value:3.53E-7 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.61|P-value:1.30E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.53|P-value:1.77E-6 ID:SGTC_2266|Compound:7929956|FD-Score:5.54|P-value:1.72E-6 ID:SGTC_2275|Compound:7947463|FD-Score:5.39|P-value:3.11E-6 ID:SGTC_2291|Compound:7917025|FD-Score:9.26|P-value:3.92E-15 ID:SGTC_2299|Compound:7976368|FD-Score:4.11|P-value:2.90E-4 ID:SGTC_2352|Compound:9027995|FD-Score:-4.15|P-value:2.34E-4 ID:SGTC_2360|Compound:9040895|FD-Score:4.01|P-value:3.94E-4 ID:SGTC_2389|Compound:9091542|FD-Score:3.72|P-value:9.19E-4 ID:SGTC_2398|Compound:5228213|FD-Score:5.29|P-value:4.59E-6 ID:SGTC_2409|Compound:alverine citrate|FD-Score:9.04|P-value:1.68E-14 ID:SGTC_2530|Compound:3-alpha-hydroxy-4,4-bisnor-8,11,13-podocarpatriene|FD-Score:-3.69|P-value:9.24E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:7.49|P-value:1.68E-10 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-4.23|P-value:1.83E-4 ID:SGTC_2586|Compound:curcumin|FD-Score:5.91|P-value:3.62E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:14.80|P-value:8.88E-36 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:15.20|P-value:8.69E-38 ID:SGTC_2651|Compound:1327-0036|FD-Score:-8.08|P-value:5.23E-12 ID:SGTC_2666|Compound:tannic acid|FD-Score:11.50|P-value:2.46E-22 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:15.50|P-value:8.64E-39 ID:SGTC_2679|Compound:rapamycin|FD-Score:-9.93|P-value:3.45E-17 ID:SGTC_2721|Compound:ifenprodil|FD-Score:21.20|P-value:2.94E-71 ID:SGTC_2725|Compound:haloperidol|FD-Score:28.50|P-value:5.02E-127 ID:SGTC_2733|Compound:amorolfine|FD-Score:14.00|P-value:5.29E-32 ID:SGTC_2735|Compound:sertaconazole|FD-Score:9.55|P-value:5.55E-16 ID:SGTC_2757|Compound:clomiphene|FD-Score:7.16|P-value:9.41E-10 ID:SGTC_2777|Compound:climbazole|FD-Score:4.33|P-value:1.44E-4 ID:SGTC_2778|Compound:tioconazole|FD-Score:11.40|P-value:6.07E-22 ID:SGTC_2784|Compound:7567673|FD-Score:5.69|P-value:9.06E-7 ID:SGTC_2790|Compound:5423970|FD-Score:15.70|P-value:3.98E-40 ID:SGTC_2792|Compound:7535235|FD-Score:10.60|P-value:3.03E-19 ID:SGTC_2825|Compound:7998094|FD-Score:11.20|P-value:2.40E-21 ID:SGTC_2838|Compound:9002687|FD-Score:27.50|P-value:2.35E-118 ID:SGTC_2867|Compound:9039098|FD-Score:4.90|P-value:2.02E-5 ID:SGTC_2880|Compound:9042983|FD-Score:20.30|P-value:2.12E-65 ID:SGTC_2887|Compound:9044784|FD-Score:25.40|P-value:1.47E-101 ID:SGTC_2893|Compound:9048488|FD-Score:16.90|P-value:5.99E-46 ID:SGTC_2896|Compound:9052656|FD-Score:12.20|P-value:1.00E-24 ID:SGTC_2910|Compound:7948405|FD-Score:9.35|P-value:2.16E-15 ID:SGTC_2938|Compound:9059746|FD-Score:15.40|P-value:1.96E-38 ID:SGTC_2948|Compound:9070189|FD-Score:21.00|P-value:3.37E-70 ID:SGTC_2981|Compound:9013952|FD-Score:6.16|P-value:1.19E-7 ID:SGTC_2986|Compound:9022445|FD-Score:6.44|P-value:3.39E-8 ID:SGTC_2991|Compound:9074669|FD-Score:18.10|P-value:2.37E-52 ID:SGTC_2993|Compound:9054257|FD-Score:24.30|P-value:9.75E-93 ID:SGTC_2999|Compound:9069765|FD-Score:4.21|P-value:2.09E-4 ID:SGTC_3018|Compound:9082602|FD-Score:8.50|P-value:5.10E-13 ID:SGTC_3027|Compound:9089541|FD-Score:4.76|P-value:3.31E-5 ID:SGTC_3033|Compound:9090887|FD-Score:17.50|P-value:2.11E-49 ID:SGTC_3037|Compound:9091026|FD-Score:4.72|P-value:3.77E-5 ID:SGTC_3040|Compound:9091894|FD-Score:8.77|P-value:9.11E-14 ID:SGTC_3041|Compound:9091929|FD-Score:4.88|P-value:2.13E-5 ID:SGTC_3054|Compound:9094397|FD-Score:12.60|P-value:2.71E-26 ID:SGTC_3071|Compound:9117417|FD-Score:12.40|P-value:1.61E-25 ID:SGTC_3080|Compound:9117754|FD-Score:-4.02|P-value:3.58E-4 ID:SGTC_3081|Compound:9117243|FD-Score:31.40|P-value:1.76E-153 ID:SGTC_3126|Compound:9127922|FD-Score:46.40|P-value:0 ID:SGTC_3135|Compound:9127742|FD-Score:-3.80|P-value:6.84E-4 ID:SGTC_3141|Compound:9094609|FD-Score:6.12|P-value:1.42E-7 ID:SGTC_3145|Compound:9085516|FD-Score:6.61|P-value:1.49E-8 ID:SGTC_3161|Compound:9100388|FD-Score:8.49|P-value:5.42E-13 ID:SGTC_3175|Compound:9106517|FD-Score:5.56|P-value:1.59E-6 ID:SGTC_3188|Compound:9110789|FD-Score:9.38|P-value:1.75E-15 ID:SGTC_3210|Compound:9128157|FD-Score:-7.67|P-value:5.61E-11 ID:SGTC_3219|Compound:9131112|FD-Score:3.71|P-value:9.47E-4 ID:SGTC_3308|Compound:9128332|FD-Score:14.60|P-value:8.43E-35 ID:SGTC_3335|Compound:9143315|FD-Score:3.77|P-value:7.92E-4 ID:SGTC_31|Compound:0508-1974|FD-Score:-4.17|P-value:2.22E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:15.50|P-value:7.29E-39 ID:SGTC_58|Compound:0957-0393|FD-Score:-8.35|P-value:1.07E-12 ID:SGTC_59|Compound:0330-0160|FD-Score:-3.89|P-value:5.21E-4 ID:SGTC_67|Compound:0335-0847|FD-Score:6.94|P-value:2.87E-9 ID:SGTC_70|Compound:0141-0289|FD-Score:18.50|P-value:1.14E-54 ID:SGTC_75|Compound:0159-0059|FD-Score:4.66|P-value:4.65E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:5.68|P-value:9.56E-7 ID:SGTC_103|Compound:0844-0104|FD-Score:5.65|P-value:1.08E-6 ID:SGTC_115|Compound:0527-0192|FD-Score:-3.82|P-value:6.43E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:3.84|P-value:6.48E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:-7.12|P-value:1.05E-9 ID:SGTC_119|Compound:0121-0043|FD-Score:5.19|P-value:6.92E-6 ID:SGTC_124|Compound:0136-0217|FD-Score:8.35|P-value:1.23E-12 ID:SGTC_137|Compound:0438-0332|FD-Score:4.90|P-value:2.03E-5 ID:SGTC_145|Compound:3737-0113|FD-Score:6.33|P-value:5.62E-8 ID:SGTC_163|Compound:1327-0036|FD-Score:-4.69|P-value:3.84E-5 ID:SGTC_178|Compound:4092-0806|FD-Score:33.10|P-value:8.17E-171 ID:SGTC_183|Compound:3914-0051|FD-Score:-5.74|P-value:6.89E-7 ID:SGTC_201|Compound:4262-0159|FD-Score:17.10|P-value:7.35E-47 ID:SGTC_207|Compound:4185-0010|FD-Score:14.80|P-value:1.46E-35 ID:SGTC_208|Compound:k072-0098|FD-Score:10.40|P-value:1.03E-18 ID:SGTC_217|Compound:ketoconazole|FD-Score:5.40|P-value:3.02E-6 ID:SGTC_218|Compound:alverine citrate|FD-Score:27.70|P-value:3.37E-120 ID:SGTC_245|Compound:methotrexate|FD-Score:3.77|P-value:8.06E-4 ID:SGTC_252|Compound:miconazole|FD-Score:10.40|P-value:1.63E-18 ID:SGTC_253|Compound:dyclonine|FD-Score:13.00|P-value:6.68E-28 ID:SGTC_254|Compound:nsc-64875|FD-Score:29.50|P-value:4.00E-136 ID:SGTC_256|Compound:clotrimazole|FD-Score:6.97|P-value:2.52E-9 ID:SGTC_258|Compound:haloperidol|FD-Score:30.60|P-value:8.41E-146 ID:SGTC_262|Compound:fenpropimorph|FD-Score:19.90|P-value:5.03E-63 ID:SGTC_263|Compound:alizarin|FD-Score:10.40|P-value:1.81E-18 ID:SGTC_264|Compound:promethazine|FD-Score:4.60|P-value:5.75E-5 ID:SGTC_278|Compound:4092-0821|FD-Score:21.70|P-value:3.07E-74 ID:SGTC_288|Compound:1315-0019|FD-Score:7.01|P-value:2.07E-9 ID:SGTC_294|Compound:k038-0071|FD-Score:5.56|P-value:1.55E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-6.59|P-value:1.48E-8 ID:SGTC_308|Compound:4092-1169|FD-Score:14.60|P-value:4.99E-35 ID:SGTC_310|Compound:1273-0058|FD-Score:-10.50|P-value:4.96E-19 ID:SGTC_312|Compound:4092-0653|FD-Score:14.50|P-value:2.44E-34 ID:SGTC_314|Compound:1671-0008|FD-Score:-5.88|P-value:3.66E-7 ID:SGTC_320|Compound:4092-0846|FD-Score:14.00|P-value:3.59E-32 ID:SGTC_340|Compound:k038-0059|FD-Score:3.69|P-value:9.96E-4 ID:SGTC_346|Compound:4513-0042|FD-Score:4.07|P-value:3.30E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:3.90|P-value:5.37E-4 ID:SGTC_352|Compound:k048-0007|FD-Score:10.70|P-value:9.97E-20 ID:SGTC_367|Compound:0335-0881|FD-Score:14.40|P-value:3.80E-34 ID:SGTC_373|Compound:0844-0104|FD-Score:14.40|P-value:4.91E-34 ID:SGTC_374|Compound:0880-0231|FD-Score:16.40|P-value:1.42E-43 ID:SGTC_384|Compound:k007-0144|FD-Score:22.10|P-value:6.35E-77 ID:SGTC_426|Compound:0988-0037|FD-Score:4.64|P-value:4.97E-5 ID:SGTC_513|Compound:4245-1575|FD-Score:-5.27|P-value:4.64E-6 ID:SGTC_514|Compound:4466-0038|FD-Score:3.74|P-value:8.66E-4 ID:SGTC_515|Compound:4092-1064|FD-Score:9.27|P-value:3.59E-15 ID:SGTC_524|Compound:r073-0010|FD-Score:4.87|P-value:2.25E-5 ID:SGTC_553|Compound:k007-0256|FD-Score:8.44|P-value:7.35E-13 ID:SGTC_568|Compound:1193-0097|FD-Score:12.40|P-value:9.77E-26 ID:SGTC_577|Compound:r071-0003|FD-Score:19.40|P-value:8.92E-60 ID:SGTC_605|Compound:1315-0399|FD-Score:3.82|P-value:6.82E-4 ID:SGTC_617|Compound:3770-0098|FD-Score:-3.85|P-value:5.87E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:15.20|P-value:1.91E-37 ID:SGTC_642|Compound:0335-0876|FD-Score:10.20|P-value:6.12E-18 ID:SGTC_646|Compound:4092-0839|FD-Score:13.90|P-value:7.19E-32 ID:SGTC_649|Compound:1123-0311|FD-Score:15.60|P-value:1.18E-39 ID:SGTC_658|Compound:3253-0951|FD-Score:10.80|P-value:7.97E-20 ID:SGTC_660|Compound:4031-1742|FD-Score:10.20|P-value:3.95E-18 ID:SGTC_669|Compound:0108-0021|FD-Score:12.70|P-value:1.14E-26 ID:SGTC_688|Compound:0527-0193|FD-Score:9.05|P-value:1.54E-14 ID:SGTC_689|Compound:0833-0039|FD-Score:12.60|P-value:1.59E-26 ID:SGTC_690|Compound:glyoxal|FD-Score:-4.71|P-value:3.63E-5 ID:SGTC_699|Compound:0375-0592|FD-Score:7.11|P-value:1.25E-9 ID:SGTC_706|Compound:4262-0057|FD-Score:12.50|P-value:6.02E-26 ID:SGTC_710|Compound:3448-4187|FD-Score:10.80|P-value:6.33E-20 ID:SGTC_733|Compound:4069-0007|FD-Score:9.06|P-value:1.43E-14 ID:SGTC_768|Compound:0384-0033|FD-Score:28.00|P-value:1.54E-122 ID:SGTC_778|Compound:3456-2434|FD-Score:3.80|P-value:7.20E-4 ID:SGTC_779|Compound:1360-0071|FD-Score:9.99|P-value:2.64E-17 ID:SGTC_788|Compound:1182-0090|FD-Score:9.90|P-value:5.05E-17 ID:SGTC_794|Compound:k038-0031|FD-Score:8.45|P-value:6.91E-13 ID:SGTC_809|Compound:3998-0021|FD-Score:5.58|P-value:1.43E-6 ID:SGTC_813|Compound:k007-0158|FD-Score:13.60|P-value:1.64E-30 ID:SGTC_834|Compound:0312-0008|FD-Score:10.40|P-value:1.79E-18 ID:SGTC_837|Compound:0091-0265|FD-Score:7.60|P-value:9.27E-11 ID:SGTC_846|Compound:0335-0850|FD-Score:8.10|P-value:5.45E-12 ID:SGTC_868|Compound:0527-0199|FD-Score:27.70|P-value:2.84E-120 ID:SGTC_875|Compound:0709-0210|FD-Score:37.70|P-value:6.60E-220 ID:SGTC_887|Compound:0885-0007|FD-Score:16.30|P-value:9.23E-43 ID:SGTC_922|Compound:1866-0035|FD-Score:-4.21|P-value:1.93E-4 ID:SGTC_941|Compound:3237-0776|FD-Score:4.07|P-value:3.26E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:6.78|P-value:6.61E-9 ID:SGTC_963|Compound:1269-2853|FD-Score:3.96|P-value:4.55E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.02|P-value:1.30E-5 ID:SGTC_977|Compound:1348-1378|FD-Score:4.25|P-value:1.85E-4 ID:SGTC_978|Compound:1416-0512|FD-Score:5.03|P-value:1.26E-5 ID:SGTC_1005|Compound:4092-0690|FD-Score:17.10|P-value:7.75E-47 ID:SGTC_1019|Compound:4262-0212|FD-Score:12.90|P-value:1.79E-27 ID:SGTC_1026|Compound:k007-1105|FD-Score:9.66|P-value:2.64E-16 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.65|P-value:2.83E-16 ID:SGTC_1076|Compound:itraconazole|FD-Score:3.97|P-value:4.44E-4 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.65|P-value:4.86E-5 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:11.50|P-value:2.73E-22 ID:SGTC_1123|Compound:mangostin|FD-Score:5.17|P-value:7.25E-6 ID:SGTC_1126|Compound:isoteolin|FD-Score:4.42|P-value:1.07E-4 ID:SGTC_1156|Compound:4092-0367|FD-Score:4.68|P-value:4.39E-5 ID:SGTC_1160|Compound:4092-0570|FD-Score:12.80|P-value:3.07E-27 ID:SGTC_1161|Compound:k007-0610|FD-Score:4.72|P-value:3.81E-5 ID:SGTC_1191|Compound:1487-1166|FD-Score:6.06|P-value:1.84E-7 ID:SGTC_1205|Compound:4161-2785|FD-Score:-6.83|P-value:4.54E-9 ID:SGTC_1230|Compound:0170-0365|FD-Score:10.20|P-value:5.25E-18 ID:SGTC_1281|Compound:0884-0031|FD-Score:7.19|P-value:8.01E-10 ID:SGTC_1286|Compound:0929-0070|FD-Score:4.36|P-value:1.29E-4 ID:SGTC_1305|Compound:1181-0477|FD-Score:3.75|P-value:8.54E-4 ID:SGTC_1306|Compound:1185-0270|FD-Score:14.20|P-value:3.21E-33 ID:SGTC_1308|Compound:1187-1617|FD-Score:20.70|P-value:7.99E-68 ID:SGTC_1313|Compound:1220-0047|FD-Score:11.50|P-value:2.88E-22 ID:SGTC_1326|Compound:1431-2094|FD-Score:3.96|P-value:4.59E-4 ID:SGTC_1341|Compound:1486-1360|FD-Score:4.11|P-value:2.84E-4 ID:SGTC_1356|Compound:1502-0781|FD-Score:6.63|P-value:1.32E-8 ID:SGTC_1422|Compound:4031-0024|FD-Score:8.91|P-value:3.85E-14 ID:SGTC_1435|Compound:4092-0789|FD-Score:9.04|P-value:1.72E-14 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.91|P-value:1.94E-5 ID:SGTC_1454|Compound:4239-0054|FD-Score:3.98|P-value:4.24E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:18.20|P-value:4.59E-53 ID:SGTC_1460|Compound:k062-0059|FD-Score:4.62|P-value:5.44E-5 ID:SGTC_1461|Compound:k072-0203|FD-Score:-4.43|P-value:9.51E-5 ID:SGTC_1475|Compound:4092-1048|FD-Score:15.80|P-value:2.19E-40 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:4.78|P-value:3.05E-5 ID:SGTC_1581|Compound:himbacine|FD-Score:6.07|P-value:1.79E-7 ID:SGTC_1619|Compound:st003326|FD-Score:-3.91|P-value:5.00E-4 ID:SGTC_1624|Compound:st003710|FD-Score:-3.92|P-value:4.76E-4 ID:SGTC_1658|Compound:st012944|FD-Score:13.50|P-value:7.33E-30 ID:SGTC_1660|Compound:st012960|FD-Score:4.64|P-value:5.11E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:5.81|P-value:5.57E-7 ID:SGTC_1729|Compound:st035615|FD-Score:4.94|P-value:1.74E-5 ID:SGTC_1731|Compound:st035964|FD-Score:5.07|P-value:1.06E-5 ID:SGTC_1741|Compound:st038134|FD-Score:-4.10|P-value:2.79E-4 ID:SGTC_1750|Compound:st081859|FD-Score:40.30|P-value:5.85E-251 ID:SGTC_1775|Compound:st081588|FD-Score:3.76|P-value:8.22E-4 ID:SGTC_1780|Compound:st038448|FD-Score:6.14|P-value:1.33E-7 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:11.70|P-value:5.72E-23 ID:SGTC_1797|Compound:st048695|FD-Score:17.80|P-value:5.27E-51 ID:SGTC_1844|Compound:rapamycin|FD-Score:-6.79|P-value:5.58E-9 ID:SGTC_1884|Compound:5633444|FD-Score:6.37|P-value:4.65E-8 ID:SGTC_1893|Compound:st059353|FD-Score:4.03|P-value:3.71E-4 ID:SGTC_1903|Compound:st060211|FD-Score:3.71|P-value:9.53E-4 ID:SGTC_1904|Compound:st060225|FD-Score:6.15|P-value:1.25E-7 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:13.20|P-value:7.38E-29 ID:SGTC_1941|Compound:st076221|FD-Score:-4.02|P-value:3.54E-4 ID:SGTC_1962|Compound:st076595|FD-Score:6.47|P-value:2.88E-8 ID:SGTC_1999|Compound:st074831|FD-Score:11.40|P-value:4.86E-22 ID:SGTC_2006|Compound:4011487|FD-Score:22.50|P-value:1.01E-79 ID:SGTC_2021|Compound:4019055|FD-Score:4.06|P-value:3.32E-4 ID:SGTC_2028|Compound:5153890|FD-Score:5.15|P-value:7.80E-6 ID:SGTC_2036|Compound:5160441|FD-Score:29.60|P-value:7.26E-137 ID:SGTC_2038|Compound:4100038|FD-Score:23.80|P-value:5.70E-89 ID:SGTC_2046|Compound:4110841|FD-Score:5.14|P-value:8.37E-6 ID:SGTC_2050|Compound:5263056|FD-Score:26.50|P-value:1.27E-109 ID:SGTC_2066|Compound:5222451|FD-Score:4.56|P-value:6.54E-5 ID:SGTC_2111|Compound:5486399|FD-Score:-3.76|P-value:7.58E-4 ID:SGTC_2129|Compound:girgensonine|FD-Score:7.10|P-value:1.30E-9 ID:SGTC_2210|Compound:7115885|FD-Score:5.92|P-value:3.53E-7 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.61|P-value:1.30E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.53|P-value:1.77E-6 ID:SGTC_2266|Compound:7929956|FD-Score:5.54|P-value:1.72E-6 ID:SGTC_2275|Compound:7947463|FD-Score:5.39|P-value:3.11E-6 ID:SGTC_2291|Compound:7917025|FD-Score:9.26|P-value:3.92E-15 ID:SGTC_2299|Compound:7976368|FD-Score:4.11|P-value:2.90E-4 ID:SGTC_2352|Compound:9027995|FD-Score:-4.15|P-value:2.34E-4 ID:SGTC_2360|Compound:9040895|FD-Score:4.01|P-value:3.94E-4 ID:SGTC_2389|Compound:9091542|FD-Score:3.72|P-value:9.19E-4 ID:SGTC_2398|Compound:5228213|FD-Score:5.29|P-value:4.59E-6 ID:SGTC_2409|Compound:alverine citrate|FD-Score:9.04|P-value:1.68E-14 ID:SGTC_2530|Compound:3-alpha-hydroxy-4,4-bisnor-8,11,13-podocarpatriene|FD-Score:-3.69|P-value:9.24E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:7.49|P-value:1.68E-10 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-4.23|P-value:1.83E-4 ID:SGTC_2586|Compound:curcumin|FD-Score:5.91|P-value:3.62E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:14.80|P-value:8.88E-36 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:15.20|P-value:8.69E-38 ID:SGTC_2651|Compound:1327-0036|FD-Score:-8.08|P-value:5.23E-12 ID:SGTC_2666|Compound:tannic acid|FD-Score:11.50|P-value:2.46E-22 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:15.50|P-value:8.64E-39 ID:SGTC_2679|Compound:rapamycin|FD-Score:-9.93|P-value:3.45E-17 ID:SGTC_2721|Compound:ifenprodil|FD-Score:21.20|P-value:2.94E-71 ID:SGTC_2725|Compound:haloperidol|FD-Score:28.50|P-value:5.02E-127 ID:SGTC_2733|Compound:amorolfine|FD-Score:14.00|P-value:5.29E-32 ID:SGTC_2735|Compound:sertaconazole|FD-Score:9.55|P-value:5.55E-16 ID:SGTC_2757|Compound:clomiphene|FD-Score:7.16|P-value:9.41E-10 ID:SGTC_2777|Compound:climbazole|FD-Score:4.33|P-value:1.44E-4 ID:SGTC_2778|Compound:tioconazole|FD-Score:11.40|P-value:6.07E-22 ID:SGTC_2784|Compound:7567673|FD-Score:5.69|P-value:9.06E-7 ID:SGTC_2790|Compound:5423970|FD-Score:15.70|P-value:3.98E-40 ID:SGTC_2792|Compound:7535235|FD-Score:10.60|P-value:3.03E-19 ID:SGTC_2825|Compound:7998094|FD-Score:11.20|P-value:2.40E-21 ID:SGTC_2838|Compound:9002687|FD-Score:27.50|P-value:2.35E-118 ID:SGTC_2867|Compound:9039098|FD-Score:4.90|P-value:2.02E-5 ID:SGTC_2880|Compound:9042983|FD-Score:20.30|P-value:2.12E-65 ID:SGTC_2887|Compound:9044784|FD-Score:25.40|P-value:1.47E-101 ID:SGTC_2893|Compound:9048488|FD-Score:16.90|P-value:5.99E-46 ID:SGTC_2896|Compound:9052656|FD-Score:12.20|P-value:1.00E-24 ID:SGTC_2910|Compound:7948405|FD-Score:9.35|P-value:2.16E-15 ID:SGTC_2938|Compound:9059746|FD-Score:15.40|P-value:1.96E-38 ID:SGTC_2948|Compound:9070189|FD-Score:21.00|P-value:3.37E-70 ID:SGTC_2981|Compound:9013952|FD-Score:6.16|P-value:1.19E-7 ID:SGTC_2986|Compound:9022445|FD-Score:6.44|P-value:3.39E-8 ID:SGTC_2991|Compound:9074669|FD-Score:18.10|P-value:2.37E-52 ID:SGTC_2993|Compound:9054257|FD-Score:24.30|P-value:9.75E-93 ID:SGTC_2999|Compound:9069765|FD-Score:4.21|P-value:2.09E-4 ID:SGTC_3018|Compound:9082602|FD-Score:8.50|P-value:5.10E-13 ID:SGTC_3027|Compound:9089541|FD-Score:4.76|P-value:3.31E-5 ID:SGTC_3033|Compound:9090887|FD-Score:17.50|P-value:2.11E-49 ID:SGTC_3037|Compound:9091026|FD-Score:4.72|P-value:3.77E-5 ID:SGTC_3040|Compound:9091894|FD-Score:8.77|P-value:9.11E-14 ID:SGTC_3041|Compound:9091929|FD-Score:4.88|P-value:2.13E-5 ID:SGTC_3054|Compound:9094397|FD-Score:12.60|P-value:2.71E-26 ID:SGTC_3071|Compound:9117417|FD-Score:12.40|P-value:1.61E-25 ID:SGTC_3080|Compound:9117754|FD-Score:-4.02|P-value:3.58E-4 ID:SGTC_3081|Compound:9117243|FD-Score:31.40|P-value:1.76E-153 ID:SGTC_3126|Compound:9127922|FD-Score:46.40|P-value:0 ID:SGTC_3135|Compound:9127742|FD-Score:-3.80|P-value:6.84E-4 ID:SGTC_3141|Compound:9094609|FD-Score:6.12|P-value:1.42E-7 ID:SGTC_3145|Compound:9085516|FD-Score:6.61|P-value:1.49E-8 ID:SGTC_3161|Compound:9100388|FD-Score:8.49|P-value:5.42E-13 ID:SGTC_3175|Compound:9106517|FD-Score:5.56|P-value:1.59E-6 ID:SGTC_3188|Compound:9110789|FD-Score:9.38|P-value:1.75E-15 ID:SGTC_3210|Compound:9128157|FD-Score:-7.67|P-value:5.61E-11 ID:SGTC_3219|Compound:9131112|FD-Score:3.71|P-value:9.47E-4 ID:SGTC_3308|Compound:9128332|FD-Score:14.60|P-value:8.43E-35 ID:SGTC_3335|Compound:9143315|FD-Score:3.77|P-value:7.92E-4

Top fitness defect scores for YDL226C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_3126 9127922 46.40 49.5 µM 0 fatty acid desaturase (OLE1) 1 0
2 SGTC_1750 st081859 40.30 2.4 µM 5.85E-251 endomembrane recycling 1 0
3 SGTC_875 0709-0210 37.70 25.7 µM 6.60E-220 fatty acid desaturase (OLE1) 1 0
4 SGTC_178 4092-0806 33.10 87.5 µM 8.17E-171 ergosterol depletion effects on membrane 1 3.45E-241
5 SGTC_3081 9117243 31.40 49.5 µM 1.76E-153 fatty acid desaturase (OLE1) 1 1.25E-216
6 SGTC_258 haloperidol 30.60 50.8 µM 8.41E-146 fatty acid desaturase (OLE1) 1 9.44E-206
7 SGTC_2036 5160441 29.60 105.0 µM 7.26E-137 NEO1 1 4.32E-193
8 SGTC_254 nsc-64875 29.50 3.8 µM 4.00E-136 ergosterol depletion effects on membrane 1 4.84E-192
9 SGTC_2725 haloperidol 28.50 53.2 µM 5.02E-127 plasma membrane duress 1 3.76E-179
10 SGTC_768 0384-0033 28.00 77.3 µM 1.54E-122 fatty acid desaturase (OLE1) 1 8.57E-173
11 SGTC_868 0527-0199 27.70 213.0 µM 2.84E-120 fatty acid desaturase (OLE1) 1 1.38E-169
12 SGTC_218 alverine citrate 27.70 93.8 µM 3.37E-120 fatty acid desaturase (OLE1) 1 1.76E-169
13 SGTC_2838 9002687 27.50 71.4 µM 2.35E-118 fatty acid desaturase (OLE1) 1 7.21E-167
14 SGTC_2050 5263056 26.50 171.0 µM 1.27E-109 fatty acid desaturase (OLE1) 1 1.70E-154
15 SGTC_2887 9044784 25.40 58.4 µM 1.47E-101 fatty acid desaturase (OLE1) 1 4.49E-143
16 SGTC_2993 9054257 24.30 71.4 µM 9.75E-93 fatty acid desaturase (OLE1) 2 1.41E-130
17 SGTC_2038 4100038 23.80 31.0 µM 5.70E-89 plasma membrane duress 3 3.05E-125
18 SGTC_2006 4011487 22.50 200.0 µM 1.01E-79 endomembrane recycling 4 3.82E-112
19 SGTC_384 k007-0144 22.10 5.2 µM 6.35E-77 ERAD & cell cycle 2 3.53E-108
20 SGTC_278 4092-0821 21.70 23.9 µM 3.07E-74 plasma membrane duress 1 2.24E-104

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.601 0 YJL204C RCY1 hom F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth
0.581 7.26E-302 YER031C YPT31 hom Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication
0.492 1.53E-203 YCR094W CDC50 hom Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication
0.475 3.91E-188 YGL055W OLE1 het Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
0.442 5.69E-160 YMR071C TVP18 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments
0.422 2.62E-145 YJR060W CBF1 hom Dual function helix-loop-helix protein; binds the motif CACRTG present at several sites including MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins and required for efficient chromosome segregation; protein abundance increases in response to DNA replication stress
0.408 9.13E-135 YOR070C GYP1 hom Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
0.406 1.98E-133 YKL135C APL2 hom Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress
0.390 1.72E-122 YDL196W_d YDL196W_d het Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame is located in promoter region of essential gene SEC31
0.389 4.05E-121 YJL207C LAA1 hom AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene
0.379 1.11E-114 YFL034W_p YFL034W_p hom Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk
0.320 5.89E-81 YAL026C DRS2 hom Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease
0.314 1.58E-77 YML007C-A_p YML007C-A_p hom Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria
0.289 2.13E-65 YJR105W ADO1 hom Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
0.287 8.53E-65 YHL019C APM2 hom Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport