YDR108W / TRS85

Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role

Zygosity: Homozygous strain
fixedexpanded
Profile for YDR108W / TRS85

Click on Significant Values for Screen Details ID:SGTC_16|Compound:erodoxin|FD-Score:5.25|P-value:4.57E-6 ID:SGTC_56|Compound:0957-0365|FD-Score:4.28|P-value:1.48E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:5.24|P-value:4.75E-6 ID:SGTC_71|Compound:0417-1750|FD-Score:4.68|P-value:3.87E-5 ID:SGTC_91|Compound:0417-1751|FD-Score:9.99|P-value:1.23E-17 ID:SGTC_119|Compound:0121-0043|FD-Score:5.41|P-value:2.33E-6 ID:SGTC_124|Compound:0136-0217|FD-Score:6.96|P-value:1.93E-9 ID:SGTC_132|Compound:0417-1715|FD-Score:4.84|P-value:2.13E-5 ID:SGTC_137|Compound:0438-0332|FD-Score:4.48|P-value:7.74E-5 ID:SGTC_244|Compound:nsc-207895|FD-Score:-3.71|P-value:7.67E-4 ID:SGTC_389|Compound:tpck|FD-Score:9.99|P-value:1.28E-17 ID:SGTC_445|Compound:e6 berbamine|FD-Score:4.98|P-value:1.26E-5 ID:SGTC_449|Compound:xestospongin c|FD-Score:4.07|P-value:2.97E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-6.22|P-value:5.62E-8 ID:SGTC_459|Compound:nigericin|FD-Score:6.69|P-value:7.27E-9 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:7.13|P-value:7.65E-10 ID:SGTC_631|Compound:k072-0230|FD-Score:3.86|P-value:5.63E-4 ID:SGTC_632|Compound:0781-2353|FD-Score:3.74|P-value:8.03E-4 ID:SGTC_671|Compound:0560-0003|FD-Score:-4.56|P-value:5.04E-5 ID:SGTC_673|Compound:1082-0474|FD-Score:-3.77|P-value:6.31E-4 ID:SGTC_697|Compound:0508-1955|FD-Score:3.89|P-value:5.07E-4 ID:SGTC_710|Compound:3448-4187|FD-Score:-3.73|P-value:7.13E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:7.48|P-value:1.18E-10 ID:SGTC_736|Compound:0958-0254|FD-Score:5.27|P-value:4.11E-6 ID:SGTC_744|Compound:1594-0068|FD-Score:9.60|P-value:2.04E-16 ID:SGTC_748|Compound:0136-0228|FD-Score:12.40|P-value:2.46E-26 ID:SGTC_813|Compound:k007-0158|FD-Score:4.11|P-value:2.60E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:3.72|P-value:8.31E-4 ID:SGTC_834|Compound:0312-0008|FD-Score:9.78|P-value:5.86E-17 ID:SGTC_838|Compound:0109-0203|FD-Score:5.13|P-value:7.15E-6 ID:SGTC_845|Compound:0330-0138|FD-Score:4.37|P-value:1.10E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:4.25|P-value:1.66E-4 ID:SGTC_875|Compound:0709-0210|FD-Score:4.10|P-value:2.65E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:8.29|P-value:1.10E-12 ID:SGTC_879|Compound:0831-1030|FD-Score:7.15|P-value:7.05E-10 ID:SGTC_994|Compound:3910-0338|FD-Score:7.13|P-value:7.71E-10 ID:SGTC_999|Compound:4022-0066|FD-Score:6.56|P-value:1.43E-8 ID:SGTC_1026|Compound:k007-1105|FD-Score:5.99|P-value:1.97E-7 ID:SGTC_1058|Compound:3448-5425|FD-Score:6.61|P-value:1.08E-8 ID:SGTC_1060|Compound:3448-7350|FD-Score:14.30|P-value:4.02E-34 ID:SGTC_1107|Compound:amlodipine|FD-Score:-4.94|P-value:1.24E-5 ID:SGTC_1182|Compound:1222-0449|FD-Score:3.90|P-value:4.97E-4 ID:SGTC_1184|Compound:1269-1718|FD-Score:3.74|P-value:7.98E-4 ID:SGTC_1279|Compound:0874-0590|FD-Score:4.48|P-value:7.55E-5 ID:SGTC_1306|Compound:1185-0270|FD-Score:10.40|P-value:4.48E-19 ID:SGTC_1313|Compound:1220-0047|FD-Score:7.14|P-value:7.32E-10 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:4.61|P-value:4.85E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:4.31|P-value:1.36E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:5.84|P-value:3.83E-7 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:4.08|P-value:2.89E-4 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:5.61|P-value:1.05E-6 ID:SGTC_1620|Compound:st003704|FD-Score:3.73|P-value:8.21E-4 ID:SGTC_1655|Compound:st012546|FD-Score:6.41|P-value:2.93E-8 ID:SGTC_1679|Compound:4130-1276|FD-Score:15.60|P-value:1.83E-40 ID:SGTC_1724|Compound:st037281|FD-Score:4.64|P-value:4.40E-5 ID:SGTC_1803|Compound:st050068|FD-Score:5.10|P-value:7.96E-6 ID:SGTC_1838|Compound:st055369|FD-Score:3.95|P-value:4.31E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:3.78|P-value:7.14E-4 ID:SGTC_1853|Compound:st056710|FD-Score:4.93|P-value:1.53E-5 ID:SGTC_1859|Compound:st055998|FD-Score:5.15|P-value:6.73E-6 ID:SGTC_1870|Compound:st057514|FD-Score:4.87|P-value:1.91E-5 ID:SGTC_1882|Compound:5615643|FD-Score:4.16|P-value:2.24E-4 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:4.70|P-value:3.50E-5 ID:SGTC_2007|Compound:4011539|FD-Score:3.90|P-value:4.90E-4 ID:SGTC_2013|Compound:4024628|FD-Score:3.82|P-value:6.25E-4 ID:SGTC_2053|Compound:5265679|FD-Score:-3.78|P-value:6.13E-4 ID:SGTC_2056|Compound:5235370|FD-Score:-3.80|P-value:5.85E-4 ID:SGTC_2131|Compound:toluylene red|FD-Score:-4.77|P-value:2.38E-5 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:5.07|P-value:9.07E-6 ID:SGTC_2413|Compound:inermin|FD-Score:8.01|P-value:5.72E-12 ID:SGTC_2460|Compound:5552655|FD-Score:6.49|P-value:2.02E-8 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:5.31|P-value:3.60E-6 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:5.05|P-value:9.67E-6 ID:SGTC_2737|Compound:bleomycin|FD-Score:5.36|P-value:2.89E-6 ID:SGTC_2739|Compound:tacrine|FD-Score:3.80|P-value:6.73E-4 ID:SGTC_2797|Compound:7859098|FD-Score:-4.19|P-value:1.72E-4 ID:SGTC_2890|Compound:9046729|FD-Score:3.99|P-value:3.74E-4 ID:SGTC_2906|Compound:7926292|FD-Score:3.98|P-value:3.90E-4 ID:SGTC_2912|Compound:7964298|FD-Score:6.68|P-value:7.77E-9 ID:SGTC_2934|Compound:9036370|FD-Score:6.00|P-value:1.92E-7 ID:SGTC_2939|Compound:9044578|FD-Score:-3.85|P-value:4.97E-4 ID:SGTC_2940|Compound:9060638|FD-Score:5.97|P-value:2.21E-7 ID:SGTC_3055|Compound:9094636|FD-Score:3.67|P-value:9.79E-4 ID:SGTC_3078|Compound:9116413|FD-Score:5.05|P-value:9.78E-6 ID:SGTC_3152|Compound:9099253|FD-Score:6.12|P-value:1.12E-7 ID:SGTC_3154|Compound:9100113|FD-Score:3.87|P-value:5.38E-4 ID:SGTC_3160|Compound:9100216|FD-Score:4.12|P-value:2.52E-4 ID:SGTC_3166|Compound:9102297|FD-Score:6.66|P-value:8.52E-9 ID:SGTC_3189|Compound:9110682|FD-Score:4.75|P-value:2.96E-5 ID:SGTC_3219|Compound:9131112|FD-Score:6.00|P-value:1.94E-7 ID:SGTC_3227|Compound:9130768|FD-Score:3.75|P-value:7.82E-4 ID:SGTC_3321|Compound:9137793|FD-Score:4.82|P-value:2.29E-5 ID:SGTC_3342|Compound:9147791|FD-Score:3.94|P-value:4.44E-4 ID:SGTC_16|Compound:erodoxin|FD-Score:5.25|P-value:4.57E-6 ID:SGTC_56|Compound:0957-0365|FD-Score:4.28|P-value:1.48E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:5.24|P-value:4.75E-6 ID:SGTC_71|Compound:0417-1750|FD-Score:4.68|P-value:3.87E-5 ID:SGTC_91|Compound:0417-1751|FD-Score:9.99|P-value:1.23E-17 ID:SGTC_119|Compound:0121-0043|FD-Score:5.41|P-value:2.33E-6 ID:SGTC_124|Compound:0136-0217|FD-Score:6.96|P-value:1.93E-9 ID:SGTC_132|Compound:0417-1715|FD-Score:4.84|P-value:2.13E-5 ID:SGTC_137|Compound:0438-0332|FD-Score:4.48|P-value:7.74E-5 ID:SGTC_244|Compound:nsc-207895|FD-Score:-3.71|P-value:7.67E-4 ID:SGTC_389|Compound:tpck|FD-Score:9.99|P-value:1.28E-17 ID:SGTC_445|Compound:e6 berbamine|FD-Score:4.98|P-value:1.26E-5 ID:SGTC_449|Compound:xestospongin c|FD-Score:4.07|P-value:2.97E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-6.22|P-value:5.62E-8 ID:SGTC_459|Compound:nigericin|FD-Score:6.69|P-value:7.27E-9 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:7.13|P-value:7.65E-10 ID:SGTC_631|Compound:k072-0230|FD-Score:3.86|P-value:5.63E-4 ID:SGTC_632|Compound:0781-2353|FD-Score:3.74|P-value:8.03E-4 ID:SGTC_671|Compound:0560-0003|FD-Score:-4.56|P-value:5.04E-5 ID:SGTC_673|Compound:1082-0474|FD-Score:-3.77|P-value:6.31E-4 ID:SGTC_697|Compound:0508-1955|FD-Score:3.89|P-value:5.07E-4 ID:SGTC_710|Compound:3448-4187|FD-Score:-3.73|P-value:7.13E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:7.48|P-value:1.18E-10 ID:SGTC_736|Compound:0958-0254|FD-Score:5.27|P-value:4.11E-6 ID:SGTC_744|Compound:1594-0068|FD-Score:9.60|P-value:2.04E-16 ID:SGTC_748|Compound:0136-0228|FD-Score:12.40|P-value:2.46E-26 ID:SGTC_813|Compound:k007-0158|FD-Score:4.11|P-value:2.60E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:3.72|P-value:8.31E-4 ID:SGTC_834|Compound:0312-0008|FD-Score:9.78|P-value:5.86E-17 ID:SGTC_838|Compound:0109-0203|FD-Score:5.13|P-value:7.15E-6 ID:SGTC_845|Compound:0330-0138|FD-Score:4.37|P-value:1.10E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:4.25|P-value:1.66E-4 ID:SGTC_875|Compound:0709-0210|FD-Score:4.10|P-value:2.65E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:8.29|P-value:1.10E-12 ID:SGTC_879|Compound:0831-1030|FD-Score:7.15|P-value:7.05E-10 ID:SGTC_994|Compound:3910-0338|FD-Score:7.13|P-value:7.71E-10 ID:SGTC_999|Compound:4022-0066|FD-Score:6.56|P-value:1.43E-8 ID:SGTC_1026|Compound:k007-1105|FD-Score:5.99|P-value:1.97E-7 ID:SGTC_1058|Compound:3448-5425|FD-Score:6.61|P-value:1.08E-8 ID:SGTC_1060|Compound:3448-7350|FD-Score:14.30|P-value:4.02E-34 ID:SGTC_1107|Compound:amlodipine|FD-Score:-4.94|P-value:1.24E-5 ID:SGTC_1182|Compound:1222-0449|FD-Score:3.90|P-value:4.97E-4 ID:SGTC_1184|Compound:1269-1718|FD-Score:3.74|P-value:7.98E-4 ID:SGTC_1279|Compound:0874-0590|FD-Score:4.48|P-value:7.55E-5 ID:SGTC_1306|Compound:1185-0270|FD-Score:10.40|P-value:4.48E-19 ID:SGTC_1313|Compound:1220-0047|FD-Score:7.14|P-value:7.32E-10 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:4.61|P-value:4.85E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:4.31|P-value:1.36E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:5.84|P-value:3.83E-7 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:4.08|P-value:2.89E-4 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:5.61|P-value:1.05E-6 ID:SGTC_1620|Compound:st003704|FD-Score:3.73|P-value:8.21E-4 ID:SGTC_1655|Compound:st012546|FD-Score:6.41|P-value:2.93E-8 ID:SGTC_1679|Compound:4130-1276|FD-Score:15.60|P-value:1.83E-40 ID:SGTC_1724|Compound:st037281|FD-Score:4.64|P-value:4.40E-5 ID:SGTC_1803|Compound:st050068|FD-Score:5.10|P-value:7.96E-6 ID:SGTC_1838|Compound:st055369|FD-Score:3.95|P-value:4.31E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:3.78|P-value:7.14E-4 ID:SGTC_1853|Compound:st056710|FD-Score:4.93|P-value:1.53E-5 ID:SGTC_1859|Compound:st055998|FD-Score:5.15|P-value:6.73E-6 ID:SGTC_1870|Compound:st057514|FD-Score:4.87|P-value:1.91E-5 ID:SGTC_1882|Compound:5615643|FD-Score:4.16|P-value:2.24E-4 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:4.70|P-value:3.50E-5 ID:SGTC_2007|Compound:4011539|FD-Score:3.90|P-value:4.90E-4 ID:SGTC_2013|Compound:4024628|FD-Score:3.82|P-value:6.25E-4 ID:SGTC_2053|Compound:5265679|FD-Score:-3.78|P-value:6.13E-4 ID:SGTC_2056|Compound:5235370|FD-Score:-3.80|P-value:5.85E-4 ID:SGTC_2131|Compound:toluylene red|FD-Score:-4.77|P-value:2.38E-5 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:5.07|P-value:9.07E-6 ID:SGTC_2413|Compound:inermin|FD-Score:8.01|P-value:5.72E-12 ID:SGTC_2460|Compound:5552655|FD-Score:6.49|P-value:2.02E-8 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:5.31|P-value:3.60E-6 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:5.05|P-value:9.67E-6 ID:SGTC_2737|Compound:bleomycin|FD-Score:5.36|P-value:2.89E-6 ID:SGTC_2739|Compound:tacrine|FD-Score:3.80|P-value:6.73E-4 ID:SGTC_2797|Compound:7859098|FD-Score:-4.19|P-value:1.72E-4 ID:SGTC_2890|Compound:9046729|FD-Score:3.99|P-value:3.74E-4 ID:SGTC_2906|Compound:7926292|FD-Score:3.98|P-value:3.90E-4 ID:SGTC_2912|Compound:7964298|FD-Score:6.68|P-value:7.77E-9 ID:SGTC_2934|Compound:9036370|FD-Score:6.00|P-value:1.92E-7 ID:SGTC_2939|Compound:9044578|FD-Score:-3.85|P-value:4.97E-4 ID:SGTC_2940|Compound:9060638|FD-Score:5.97|P-value:2.21E-7 ID:SGTC_3055|Compound:9094636|FD-Score:3.67|P-value:9.79E-4 ID:SGTC_3078|Compound:9116413|FD-Score:5.05|P-value:9.78E-6 ID:SGTC_3152|Compound:9099253|FD-Score:6.12|P-value:1.12E-7 ID:SGTC_3154|Compound:9100113|FD-Score:3.87|P-value:5.38E-4 ID:SGTC_3160|Compound:9100216|FD-Score:4.12|P-value:2.52E-4 ID:SGTC_3166|Compound:9102297|FD-Score:6.66|P-value:8.52E-9 ID:SGTC_3189|Compound:9110682|FD-Score:4.75|P-value:2.96E-5 ID:SGTC_3219|Compound:9131112|FD-Score:6.00|P-value:1.94E-7 ID:SGTC_3227|Compound:9130768|FD-Score:3.75|P-value:7.82E-4 ID:SGTC_3321|Compound:9137793|FD-Score:4.82|P-value:2.29E-5 ID:SGTC_3342|Compound:9147791|FD-Score:3.94|P-value:4.44E-4

Top fitness defect scores for YDR108W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1679 4130-1276 15.60 6.7 µM 1.83E-40 Golgi 2 1.95E-55
2 SGTC_1060 3448-7350 14.30 82.0 µM 4.02E-34 Golgi 3 1.20E-46
3 SGTC_748 0136-0228 12.40 77.9 µM 2.46E-26 redox potentiating 5 7.35E-36
4 SGTC_1306 1185-0270 10.40 9.0 µM 4.48E-19 Golgi 9 8.29E-26
5 SGTC_91 0417-1751 9.99 58.4 µM 1.23E-17 Golgi 7 8.13E-24
6 SGTC_389 tpck 9.99 16.7 µM 1.28E-17 4 8.56E-24
7 SGTC_834 0312-0008 9.78 75.7 µM 5.86E-17 NEO1 3 7.04E-23
8 SGTC_744 1594-0068 9.60 283.0 µM 2.04E-16 amide catabolism 2 3.95E-22
9 SGTC_878 0828-0289 8.29 13.7 µM 1.10E-12 7 5.72E-17
10 SGTC_2413 inermin 8.01 26.1 µM 5.72E-12 6 5.60E-16
11 SGTC_733 4069-0007 7.48 56.1 µM 1.18E-10 ERAD & cell cycle 24 3.69E-14
12 SGTC_879 0831-1030 7.15 162.0 µM 7.05E-10 9 4.34E-13
13 SGTC_1313 1220-0047 7.14 237.0 µM 7.32E-10 11 4.57E-13
14 SGTC_498 2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ) 7.13 150.0 µM 7.65E-10 Golgi 11 4.85E-13
15 SGTC_994 3910-0338 7.13 138.0 µM 7.71E-10 calcium & mitochondrial duress 7 4.90E-13
16 SGTC_124 0136-0217 6.96 7.1 µM 1.93E-9 mitochondrial stress 17 1.74E-12
17 SGTC_459 nigericin 6.69 15.3 µM 7.27E-9 24 1.09E-11
18 SGTC_2912 7964298 6.68 10.9 µM 7.77E-9 cell wall 38 1.19E-11
19 SGTC_3166 9102297 6.66 49.5 µM 8.52E-9 Golgi 7 1.35E-11
20 SGTC_1058 3448-5425 6.61 97.3 µM 1.08E-8 12 1.88E-11

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.329 3.86E-85 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.316 7.64E-79 YBR164C ARL1 hom Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
0.308 1.69E-74 YFL038C YPT1 het Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
0.305 6.93E-73 YJL004C SYS1 hom Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation
0.292 3.57E-67 YOL146W PSF3 het Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
0.286 2.34E-64 YML071C COG8 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.278 1.82E-60 YPL051W ARL3 hom GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
0.271 2.65E-57 YGL005C COG7 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.224 3.18E-39 YNL041C COG6 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.205 4.29E-33 YMR079W SEC14 het Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; has a role in localization of lipid raft proteins; functionally homologous to mammalian PITPs
0.203 1.85E-32 YOL018C TLG2 hom Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)
0.188 4.29E-28 YOR070C GYP1 hom Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
0.170 4.50E-23 YER083C GET2 hom Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division
0.163 2.64E-21 YLR309C IMH1 hom Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi
0.159 2.37E-20 YNL051W COG5 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments