YDR389W / SAC7

GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate

Zygosity: Homozygous strain
fixedexpanded
Profile for YDR389W / SAC7

Click on Significant Values for Screen Details ID:SGTC_9|Compound:0092-0002|FD-Score:7.17|P-value:1.41E-9 ID:SGTC_15|Compound:0266-0086|FD-Score:8.85|P-value:8.89E-14 ID:SGTC_16|Compound:erodoxin|FD-Score:6.85|P-value:6.78E-9 ID:SGTC_29|Compound:0299-0004|FD-Score:6.21|P-value:1.41E-7 ID:SGTC_43|Compound:0570-0105|FD-Score:9.57|P-value:8.31E-16 ID:SGTC_58|Compound:0957-0393|FD-Score:4.07|P-value:4.24E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:8.88|P-value:7.45E-14 ID:SGTC_117|Compound:lucigenin|FD-Score:9.15|P-value:1.37E-14 ID:SGTC_118|Compound:0083-0097|FD-Score:-3.73|P-value:6.06E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:5.03|P-value:1.75E-5 ID:SGTC_151|Compound:3013-0144|FD-Score:4.30|P-value:2.13E-4 ID:SGTC_207|Compound:4185-0010|FD-Score:4.72|P-value:5.29E-5 ID:SGTC_214|Compound:4373-3496|FD-Score:4.14|P-value:3.52E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:4.85|P-value:3.34E-5 ID:SGTC_227|Compound:fluconazole|FD-Score:5.43|P-value:3.81E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-4.61|P-value:3.43E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:-3.66|P-value:7.34E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.75|P-value:3.91E-7 ID:SGTC_312|Compound:4092-0653|FD-Score:-4.11|P-value:1.83E-4 ID:SGTC_313|Compound:3474-0040|FD-Score:4.80|P-value:3.89E-5 ID:SGTC_327|Compound:1273-0057|FD-Score:-4.36|P-value:8.06E-5 ID:SGTC_339|Compound:3091-4833|FD-Score:5.46|P-value:3.32E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:7.37|P-value:4.76E-10 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:3.84|P-value:8.55E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-3.70|P-value:6.58E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:12.30|P-value:3.59E-25 ID:SGTC_525|Compound:k781-2675|FD-Score:4.57|P-value:8.74E-5 ID:SGTC_528|Compound:3492-0019|FD-Score:4.66|P-value:6.44E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:4.03|P-value:4.89E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:4.82|P-value:3.69E-5 ID:SGTC_660|Compound:4031-1742|FD-Score:5.83|P-value:7.31E-7 ID:SGTC_733|Compound:4069-0007|FD-Score:9.34|P-value:3.75E-15 ID:SGTC_805|Compound:3852-0218|FD-Score:4.21|P-value:2.82E-4 ID:SGTC_853|Compound:0419-0306|FD-Score:5.19|P-value:9.40E-6 ID:SGTC_867|Compound:0518-0118|FD-Score:5.13|P-value:1.17E-5 ID:SGTC_907|Compound:3448-6986|FD-Score:4.28|P-value:2.24E-4 ID:SGTC_912|Compound:3474-0017|FD-Score:3.97|P-value:5.77E-4 ID:SGTC_916|Compound:4466-0038|FD-Score:8.23|P-value:4.01E-12 ID:SGTC_999|Compound:4022-0066|FD-Score:7.50|P-value:2.47E-10 ID:SGTC_1026|Compound:k007-1105|FD-Score:6.16|P-value:1.72E-7 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.22|P-value:2.69E-4 ID:SGTC_1090|Compound:efavirenz|FD-Score:6.51|P-value:3.58E-8 ID:SGTC_1098|Compound:clofazimine|FD-Score:5.31|P-value:5.99E-6 ID:SGTC_1104|Compound:tacrolimus|FD-Score:4.99|P-value:1.97E-5 ID:SGTC_1118|Compound:chelidonine|FD-Score:-4.58|P-value:3.83E-5 ID:SGTC_1472|Compound:k841-0093|FD-Score:4.63|P-value:7.03E-5 ID:SGTC_1523|Compound:st012844|FD-Score:3.96|P-value:5.94E-4 ID:SGTC_1528|Compound:arabinosylhypoxanthine|FD-Score:-4.01|P-value:2.57E-4 ID:SGTC_1672|Compound:st016598|FD-Score:6.50|P-value:3.68E-8 ID:SGTC_1679|Compound:4130-1276|FD-Score:6.14|P-value:1.89E-7 ID:SGTC_1712|Compound:st032288|FD-Score:4.23|P-value:2.61E-4 ID:SGTC_1729|Compound:st035615|FD-Score:3.86|P-value:7.92E-4 ID:SGTC_1754|Compound:st042065|FD-Score:10.40|P-value:1.57E-18 ID:SGTC_1800|Compound:st050079|FD-Score:4.63|P-value:7.01E-5 ID:SGTC_1801|Compound:st050089|FD-Score:4.48|P-value:1.19E-4 ID:SGTC_1812|Compound:st052057|FD-Score:4.15|P-value:3.41E-4 ID:SGTC_1818|Compound:st052136|FD-Score:4.14|P-value:3.49E-4 ID:SGTC_1855|Compound:st056195|FD-Score:4.06|P-value:4.39E-4 ID:SGTC_1874|Compound:staurosporine|FD-Score:6.23|P-value:1.27E-7 ID:SGTC_1893|Compound:st059353|FD-Score:5.82|P-value:7.66E-7 ID:SGTC_1903|Compound:st060211|FD-Score:5.11|P-value:1.28E-5 ID:SGTC_2056|Compound:5235370|FD-Score:-5.13|P-value:4.98E-6 ID:SGTC_2242|Compound:6630449|FD-Score:4.77|P-value:4.40E-5 ID:SGTC_2289|Compound:7946404|FD-Score:4.33|P-value:1.91E-4 ID:SGTC_2307|Compound:7538926|FD-Score:-6.59|P-value:8.06E-9 ID:SGTC_2322|Compound:7413319|FD-Score:6.92|P-value:4.79E-9 ID:SGTC_2351|Compound:9026858|FD-Score:4.48|P-value:1.16E-4 ID:SGTC_2358|Compound:9037157|FD-Score:-3.82|P-value:4.63E-4 ID:SGTC_2411|Compound:st077133|FD-Score:-5.14|P-value:4.77E-6 ID:SGTC_2581|Compound:avocatin a|FD-Score:-3.59|P-value:8.98E-4 ID:SGTC_2584|Compound:androsterone|FD-Score:3.90|P-value:7.22E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:5.84|P-value:6.93E-7 ID:SGTC_2651|Compound:1327-0036|FD-Score:-5.67|P-value:5.39E-7 ID:SGTC_2662|Compound:daunorubicin|FD-Score:5.68|P-value:1.40E-6 ID:SGTC_2776|Compound:terbinafine|FD-Score:4.40|P-value:1.53E-4 ID:SGTC_2779|Compound:methotrexate|FD-Score:4.21|P-value:2.81E-4 ID:SGTC_2807|Compound:7945238|FD-Score:-4.31|P-value:9.69E-5 ID:SGTC_2810|Compound:7959871|FD-Score:4.43|P-value:1.39E-4 ID:SGTC_2848|Compound:9016370|FD-Score:4.37|P-value:1.67E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-5.05|P-value:6.64E-6 ID:SGTC_2867|Compound:9039098|FD-Score:4.85|P-value:3.28E-5 ID:SGTC_2912|Compound:7964298|FD-Score:10.70|P-value:1.74E-19 ID:SGTC_2969|Compound:9091408|FD-Score:-7.87|P-value:8.39E-12 ID:SGTC_2970|Compound:9090938|FD-Score:-5.14|P-value:4.79E-6 ID:SGTC_2974|Compound:9094440|FD-Score:6.50|P-value:3.71E-8 ID:SGTC_2997|Compound:9067075|FD-Score:4.97|P-value:2.19E-5 ID:SGTC_3037|Compound:9091026|FD-Score:7.92|P-value:2.44E-11 ID:SGTC_3072|Compound:9116419|FD-Score:-4.54|P-value:4.33E-5 ID:SGTC_3152|Compound:9099253|FD-Score:4.72|P-value:5.29E-5 ID:SGTC_3210|Compound:9128157|FD-Score:-5.32|P-value:2.36E-6 ID:SGTC_3311|Compound:9131146|FD-Score:4.09|P-value:4.02E-4 ID:SGTC_3322|Compound:9139058|FD-Score:3.79|P-value:9.66E-4 ID:SGTC_9|Compound:0092-0002|FD-Score:7.17|P-value:1.41E-9 ID:SGTC_15|Compound:0266-0086|FD-Score:8.85|P-value:8.89E-14 ID:SGTC_16|Compound:erodoxin|FD-Score:6.85|P-value:6.78E-9 ID:SGTC_29|Compound:0299-0004|FD-Score:6.21|P-value:1.41E-7 ID:SGTC_43|Compound:0570-0105|FD-Score:9.57|P-value:8.31E-16 ID:SGTC_58|Compound:0957-0393|FD-Score:4.07|P-value:4.24E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:8.88|P-value:7.45E-14 ID:SGTC_117|Compound:lucigenin|FD-Score:9.15|P-value:1.37E-14 ID:SGTC_118|Compound:0083-0097|FD-Score:-3.73|P-value:6.06E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:5.03|P-value:1.75E-5 ID:SGTC_151|Compound:3013-0144|FD-Score:4.30|P-value:2.13E-4 ID:SGTC_207|Compound:4185-0010|FD-Score:4.72|P-value:5.29E-5 ID:SGTC_214|Compound:4373-3496|FD-Score:4.14|P-value:3.52E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:4.85|P-value:3.34E-5 ID:SGTC_227|Compound:fluconazole|FD-Score:5.43|P-value:3.81E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-4.61|P-value:3.43E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:-3.66|P-value:7.34E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.75|P-value:3.91E-7 ID:SGTC_312|Compound:4092-0653|FD-Score:-4.11|P-value:1.83E-4 ID:SGTC_313|Compound:3474-0040|FD-Score:4.80|P-value:3.89E-5 ID:SGTC_327|Compound:1273-0057|FD-Score:-4.36|P-value:8.06E-5 ID:SGTC_339|Compound:3091-4833|FD-Score:5.46|P-value:3.32E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:7.37|P-value:4.76E-10 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:3.84|P-value:8.55E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-3.70|P-value:6.58E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:12.30|P-value:3.59E-25 ID:SGTC_525|Compound:k781-2675|FD-Score:4.57|P-value:8.74E-5 ID:SGTC_528|Compound:3492-0019|FD-Score:4.66|P-value:6.44E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:4.03|P-value:4.89E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:4.82|P-value:3.69E-5 ID:SGTC_660|Compound:4031-1742|FD-Score:5.83|P-value:7.31E-7 ID:SGTC_733|Compound:4069-0007|FD-Score:9.34|P-value:3.75E-15 ID:SGTC_805|Compound:3852-0218|FD-Score:4.21|P-value:2.82E-4 ID:SGTC_853|Compound:0419-0306|FD-Score:5.19|P-value:9.40E-6 ID:SGTC_867|Compound:0518-0118|FD-Score:5.13|P-value:1.17E-5 ID:SGTC_907|Compound:3448-6986|FD-Score:4.28|P-value:2.24E-4 ID:SGTC_912|Compound:3474-0017|FD-Score:3.97|P-value:5.77E-4 ID:SGTC_916|Compound:4466-0038|FD-Score:8.23|P-value:4.01E-12 ID:SGTC_999|Compound:4022-0066|FD-Score:7.50|P-value:2.47E-10 ID:SGTC_1026|Compound:k007-1105|FD-Score:6.16|P-value:1.72E-7 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.22|P-value:2.69E-4 ID:SGTC_1090|Compound:efavirenz|FD-Score:6.51|P-value:3.58E-8 ID:SGTC_1098|Compound:clofazimine|FD-Score:5.31|P-value:5.99E-6 ID:SGTC_1104|Compound:tacrolimus|FD-Score:4.99|P-value:1.97E-5 ID:SGTC_1118|Compound:chelidonine|FD-Score:-4.58|P-value:3.83E-5 ID:SGTC_1472|Compound:k841-0093|FD-Score:4.63|P-value:7.03E-5 ID:SGTC_1523|Compound:st012844|FD-Score:3.96|P-value:5.94E-4 ID:SGTC_1528|Compound:arabinosylhypoxanthine|FD-Score:-4.01|P-value:2.57E-4 ID:SGTC_1672|Compound:st016598|FD-Score:6.50|P-value:3.68E-8 ID:SGTC_1679|Compound:4130-1276|FD-Score:6.14|P-value:1.89E-7 ID:SGTC_1712|Compound:st032288|FD-Score:4.23|P-value:2.61E-4 ID:SGTC_1729|Compound:st035615|FD-Score:3.86|P-value:7.92E-4 ID:SGTC_1754|Compound:st042065|FD-Score:10.40|P-value:1.57E-18 ID:SGTC_1800|Compound:st050079|FD-Score:4.63|P-value:7.01E-5 ID:SGTC_1801|Compound:st050089|FD-Score:4.48|P-value:1.19E-4 ID:SGTC_1812|Compound:st052057|FD-Score:4.15|P-value:3.41E-4 ID:SGTC_1818|Compound:st052136|FD-Score:4.14|P-value:3.49E-4 ID:SGTC_1855|Compound:st056195|FD-Score:4.06|P-value:4.39E-4 ID:SGTC_1874|Compound:staurosporine|FD-Score:6.23|P-value:1.27E-7 ID:SGTC_1893|Compound:st059353|FD-Score:5.82|P-value:7.66E-7 ID:SGTC_1903|Compound:st060211|FD-Score:5.11|P-value:1.28E-5 ID:SGTC_2056|Compound:5235370|FD-Score:-5.13|P-value:4.98E-6 ID:SGTC_2242|Compound:6630449|FD-Score:4.77|P-value:4.40E-5 ID:SGTC_2289|Compound:7946404|FD-Score:4.33|P-value:1.91E-4 ID:SGTC_2307|Compound:7538926|FD-Score:-6.59|P-value:8.06E-9 ID:SGTC_2322|Compound:7413319|FD-Score:6.92|P-value:4.79E-9 ID:SGTC_2351|Compound:9026858|FD-Score:4.48|P-value:1.16E-4 ID:SGTC_2358|Compound:9037157|FD-Score:-3.82|P-value:4.63E-4 ID:SGTC_2411|Compound:st077133|FD-Score:-5.14|P-value:4.77E-6 ID:SGTC_2581|Compound:avocatin a|FD-Score:-3.59|P-value:8.98E-4 ID:SGTC_2584|Compound:androsterone|FD-Score:3.90|P-value:7.22E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:5.84|P-value:6.93E-7 ID:SGTC_2651|Compound:1327-0036|FD-Score:-5.67|P-value:5.39E-7 ID:SGTC_2662|Compound:daunorubicin|FD-Score:5.68|P-value:1.40E-6 ID:SGTC_2776|Compound:terbinafine|FD-Score:4.40|P-value:1.53E-4 ID:SGTC_2779|Compound:methotrexate|FD-Score:4.21|P-value:2.81E-4 ID:SGTC_2807|Compound:7945238|FD-Score:-4.31|P-value:9.69E-5 ID:SGTC_2810|Compound:7959871|FD-Score:4.43|P-value:1.39E-4 ID:SGTC_2848|Compound:9016370|FD-Score:4.37|P-value:1.67E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-5.05|P-value:6.64E-6 ID:SGTC_2867|Compound:9039098|FD-Score:4.85|P-value:3.28E-5 ID:SGTC_2912|Compound:7964298|FD-Score:10.70|P-value:1.74E-19 ID:SGTC_2969|Compound:9091408|FD-Score:-7.87|P-value:8.39E-12 ID:SGTC_2970|Compound:9090938|FD-Score:-5.14|P-value:4.79E-6 ID:SGTC_2974|Compound:9094440|FD-Score:6.50|P-value:3.71E-8 ID:SGTC_2997|Compound:9067075|FD-Score:4.97|P-value:2.19E-5 ID:SGTC_3037|Compound:9091026|FD-Score:7.92|P-value:2.44E-11 ID:SGTC_3072|Compound:9116419|FD-Score:-4.54|P-value:4.33E-5 ID:SGTC_3152|Compound:9099253|FD-Score:4.72|P-value:5.29E-5 ID:SGTC_3210|Compound:9128157|FD-Score:-5.32|P-value:2.36E-6 ID:SGTC_3311|Compound:9131146|FD-Score:4.09|P-value:4.02E-4 ID:SGTC_3322|Compound:9139058|FD-Score:3.79|P-value:9.66E-4

Top fitness defect scores for YDR389W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_514 4466-0038 12.30 2.6 nM 3.59E-25 cell wall 15 2.88E-35
2 SGTC_2912 7964298 10.70 10.9 µM 1.74E-19 cell wall 12 3.34E-27
3 SGTC_1754 st042065 10.40 16.1 µM 1.57E-18 NEO1-PIK1 21 7.58E-26
4 SGTC_43 0570-0105 9.57 72.5 µM 8.31E-16 ERG2 11 5.52E-22
5 SGTC_733 4069-0007 9.34 56.1 µM 3.75E-15 ERAD & cell cycle 18 4.68E-21
6 SGTC_117 lucigenin 9.15 22.1 µM 1.37E-14 redox potentiating 11 2.95E-20
7 SGTC_70 0141-0289 8.88 43.3 µM 7.45E-14 mitochondrial stress 27 3.26E-19
8 SGTC_15 0266-0086 8.85 27.1 µM 8.89E-14 endomembrane recycling 7 4.19E-19
9 SGTC_916 4466-0038 8.23 42.0 nM 4.01E-12 cell wall 11 9.35E-17
10 SGTC_3037 9091026 7.92 49.5 µM 2.44E-11 NEO1-PIK1 15 1.21E-15
11 SGTC_999 4022-0066 7.50 22.7 µM 2.47E-10 Golgi 8 3.25E-14
12 SGTC_351 caspofungin 7.37 25.0 nM 4.76E-10 cell wall 22 8.22E-14
13 SGTC_9 0092-0002 7.17 10.4 µM 1.41E-9 4 3.85E-13
14 SGTC_2322 7413319 6.92 38.2 µM 4.79E-9 ERAD & cell cycle 51 2.18E-12
15 SGTC_16 erodoxin 6.85 22.8 µM 6.78E-9 unfolded protein response 19 3.58E-12
16 SGTC_1090 efavirenz 6.51 20.7 µM 3.58E-8 1 3.80E-11
17 SGTC_1672 st016598 6.50 6.5 µM 3.68E-8 endomembrane recycling 28 3.95E-11
18 SGTC_2974 9094440 6.50 9.7 µM 3.71E-8 ergosterol biosynthesis 7 4.00E-11
19 SGTC_1874 staurosporine 6.23 7.6 µM 1.27E-7 cell wall signaling 10 2.30E-10
20 SGTC_29 0299-0004 6.21 13.0 µM 1.41E-7 10 2.66E-10

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.270 4.46E-57 YLR330W CHS5 hom Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane
0.254 2.00E-50 YBL061C SKT5 hom Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication
0.237 3.16E-44 YDR348C PAL1 hom Protein of unknown function thought to be involved in endocytosis; Pal1p physically interacts with Ede1p and is found at endocytic sites at the cell periphery during the early stages of endocytosis; green fluorescent protein (GFP)-fusion protein also localizes to the bud neck; potential Cdc28p substrate; similar to the S. pombe Pal1 protein; relocalizes from bud neck to cytoplasm upon DNA replication stress
0.236 1.39E-43 YDR162C NBP2 hom Protein involved in the HOG (high osmolarity glycerol) pathway; negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex; interacts with Bck1p and down regulates the cell wall integrity pathway; found in the nucleus and cytoplasm, contains an SH3 domain and a Ptc1p binding domain (PBM)
0.234 5.44E-43 YNL267W PIK1 het Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton
0.223 5.69E-39 YGR166W TRS65 hom Subunit of TRAPPII, a multimeric guanine nucleotide-exchange factor for Ypt1p; involved in intra-Golgi traffic and the retrograde pathway from the endosome to Golgi; role in cell wall beta-glucan biosynthesis and the stress response
0.216 1.04E-36 YNL079C TPM1 hom Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication
0.216 1.19E-36 YOL003C PFA4 hom Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases
0.210 7.10E-35 YKL145W RPT1 het One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance
0.208 2.73E-34 YLL043W FPS1 hom Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress
0.207 6.94E-34 YJL099W CHS6 hom Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
0.200 1.39E-31 YDR351W SBE2 hom Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth
0.198 4.92E-31 YJR102C VPS25 hom Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome
0.198 6.11E-31 YJL081C ARP4 het Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
0.198 7.14E-31 YGL035C MIG1 hom Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion