YDR455C_d

Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YDR456W

Zygosity: Homozygous strain
fixedexpanded
Profile for YDR455C / YDR455C

Click on Significant Values for Screen Details ID:SGTC_15|Compound:0266-0086|FD-Score:5.89|P-value:2.75E-7 ID:SGTC_40|Compound:0327-0103|FD-Score:-3.66|P-value:8.00E-4 ID:SGTC_57|Compound:miconazole|FD-Score:-3.82|P-value:5.00E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:-7.79|P-value:1.15E-11 ID:SGTC_103|Compound:0844-0104|FD-Score:3.99|P-value:3.61E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:11.40|P-value:1.87E-22 ID:SGTC_137|Compound:0438-0332|FD-Score:4.58|P-value:5.12E-5 ID:SGTC_164|Compound:4100-3994|FD-Score:6.09|P-value:1.11E-7 ID:SGTC_167|Compound:3672-0051|FD-Score:-3.90|P-value:3.85E-4 ID:SGTC_172|Compound:1112-0046|FD-Score:3.92|P-value:4.41E-4 ID:SGTC_206|Compound:4546-0025|FD-Score:29.00|P-value:2.86E-135 ID:SGTC_221|Compound:trifluoperazine|FD-Score:18.40|P-value:6.68E-56 ID:SGTC_232|Compound:clozapine|FD-Score:26.40|P-value:2.47E-112 ID:SGTC_245|Compound:methotrexate|FD-Score:7.24|P-value:3.60E-10 ID:SGTC_255|Compound:tunicamycin|FD-Score:11.90|P-value:2.25E-24 ID:SGTC_263|Compound:alizarin|FD-Score:6.49|P-value:1.73E-8 ID:SGTC_266|Compound:formosanin C|FD-Score:-4.18|P-value:1.61E-4 ID:SGTC_278|Compound:4092-0821|FD-Score:-3.97|P-value:3.15E-4 ID:SGTC_297|Compound:0986-0032|FD-Score:-3.61|P-value:9.29E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:28.10|P-value:8.41E-128 ID:SGTC_304|Compound:1310-0298|FD-Score:-5.28|P-value:2.86E-6 ID:SGTC_309|Compound:k408-0051|FD-Score:-3.93|P-value:3.51E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.88|P-value:1.36E-5 ID:SGTC_313|Compound:3474-0040|FD-Score:7.82|P-value:1.43E-11 ID:SGTC_314|Compound:1671-0008|FD-Score:-3.68|P-value:7.45E-4 ID:SGTC_315|Compound:k915-0449|FD-Score:4.88|P-value:1.70E-5 ID:SGTC_337|Compound:1315-0038|FD-Score:13.00|P-value:1.03E-28 ID:SGTC_339|Compound:3091-4833|FD-Score:4.54|P-value:5.89E-5 ID:SGTC_352|Compound:k048-0007|FD-Score:6.52|P-value:1.49E-8 ID:SGTC_364|Compound:0083-0097|FD-Score:-4.21|P-value:1.42E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:4.23|P-value:1.65E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:6.63|P-value:8.47E-9 ID:SGTC_443|Compound:clozapine|FD-Score:4.81|P-value:2.19E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:9.53|P-value:2.48E-16 ID:SGTC_447|Compound:ml7|FD-Score:5.51|P-value:1.43E-6 ID:SGTC_449|Compound:xestospongin c|FD-Score:8.52|P-value:2.06E-13 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-7.69|P-value:2.07E-11 ID:SGTC_455|Compound:paf C-16|FD-Score:-4.54|P-value:4.69E-5 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:4.03|P-value:3.20E-4 ID:SGTC_528|Compound:3492-0019|FD-Score:16.30|P-value:1.77E-44 ID:SGTC_535|Compound:2293-4129|FD-Score:31.00|P-value:3.50E-154 ID:SGTC_561|Compound:1550-0330|FD-Score:-3.72|P-value:6.75E-4 ID:SGTC_568|Compound:1193-0097|FD-Score:7.12|P-value:6.90E-10 ID:SGTC_577|Compound:r071-0003|FD-Score:4.37|P-value:1.07E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:4.51|P-value:6.53E-5 ID:SGTC_607|Compound:4491-0986|FD-Score:4.25|P-value:1.55E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:6.78|P-value:4.00E-9 ID:SGTC_690|Compound:glyoxal|FD-Score:-3.95|P-value:3.37E-4 ID:SGTC_692|Compound:k241-0027|FD-Score:6.40|P-value:2.61E-8 ID:SGTC_697|Compound:0508-1955|FD-Score:14.70|P-value:1.61E-36 ID:SGTC_711|Compound:k292-0785|FD-Score:-6.38|P-value:2.09E-8 ID:SGTC_754|Compound:3474-0146|FD-Score:5.33|P-value:2.94E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:5.12|P-value:6.89E-6 ID:SGTC_794|Compound:k038-0031|FD-Score:5.76|P-value:4.98E-7 ID:SGTC_805|Compound:3852-0218|FD-Score:4.82|P-value:2.14E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:-3.87|P-value:4.31E-4 ID:SGTC_875|Compound:0709-0210|FD-Score:5.34|P-value:2.88E-6 ID:SGTC_888|Compound:0916-0002|FD-Score:11.80|P-value:4.31E-24 ID:SGTC_900|Compound:1112-0045|FD-Score:9.53|P-value:2.44E-16 ID:SGTC_940|Compound:3232-1287|FD-Score:7.06|P-value:9.63E-10 ID:SGTC_955|Compound:1216-0110|FD-Score:3.67|P-value:9.35E-4 ID:SGTC_987|Compound:1497-1013|FD-Score:5.97|P-value:1.96E-7 ID:SGTC_993|Compound:3909-8757|FD-Score:8.24|P-value:1.16E-12 ID:SGTC_997|Compound:3996-0078|FD-Score:3.97|P-value:3.78E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:6.83|P-value:3.07E-9 ID:SGTC_1049|Compound:3226-0134|FD-Score:3.65|P-value:9.99E-4 ID:SGTC_1071|Compound:trifluoperazine|FD-Score:5.98|P-value:1.82E-7 ID:SGTC_1081|Compound:sertraline|FD-Score:7.72|P-value:2.50E-11 ID:SGTC_1103|Compound:duloxetine|FD-Score:4.03|P-value:3.16E-4 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:8.97|P-value:1.09E-14 ID:SGTC_1130|Compound:3454-2858|FD-Score:8.62|P-value:1.05E-13 ID:SGTC_1161|Compound:k007-0610|FD-Score:3.66|P-value:9.75E-4 ID:SGTC_1174|Compound:0739-0097|FD-Score:5.49|P-value:1.57E-6 ID:SGTC_1253|Compound:0550-0034|FD-Score:3.89|P-value:4.94E-4 ID:SGTC_1254|Compound:0550-0035|FD-Score:3.82|P-value:6.13E-4 ID:SGTC_1257|Compound:0669-0121|FD-Score:3.73|P-value:7.84E-4 ID:SGTC_1262|Compound:0737-0114|FD-Score:3.82|P-value:6.05E-4 ID:SGTC_1394|Compound:3474-0001|FD-Score:8.68|P-value:7.18E-14 ID:SGTC_1495|Compound:4469-0029|FD-Score:6.75|P-value:4.65E-9 ID:SGTC_1522|Compound:st012842|FD-Score:-3.60|P-value:9.57E-4 ID:SGTC_1547|Compound:harmine|FD-Score:9.79|P-value:3.68E-17 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.93|P-value:4.38E-4 ID:SGTC_1612|Compound:st002233|FD-Score:4.51|P-value:6.44E-5 ID:SGTC_1658|Compound:st012944|FD-Score:6.59|P-value:1.07E-8 ID:SGTC_1665|Compound:st014639|FD-Score:6.65|P-value:7.65E-9 ID:SGTC_1750|Compound:st081859|FD-Score:9.86|P-value:2.23E-17 ID:SGTC_1754|Compound:st042065|FD-Score:6.89|P-value:2.30E-9 ID:SGTC_1760|Compound:st045453|FD-Score:11.00|P-value:2.49E-21 ID:SGTC_1781|Compound:st038725|FD-Score:25.90|P-value:6.35E-109 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:4.60|P-value:4.69E-5 ID:SGTC_1789|Compound:tunicamycin|FD-Score:10.10|P-value:3.38E-18 ID:SGTC_1797|Compound:st048695|FD-Score:5.44|P-value:1.91E-6 ID:SGTC_1803|Compound:st050068|FD-Score:6.38|P-value:2.94E-8 ID:SGTC_1810|Compound:st050138|FD-Score:3.72|P-value:8.14E-4 ID:SGTC_1920|Compound:st075728|FD-Score:5.08|P-value:7.94E-6 ID:SGTC_1921|Compound:5740136|FD-Score:-3.62|P-value:9.00E-4 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:7.34|P-value:2.16E-10 ID:SGTC_1933|Compound:st074711|FD-Score:7.24|P-value:3.64E-10 ID:SGTC_1991|Compound:st073000|FD-Score:9.75|P-value:4.98E-17 ID:SGTC_2006|Compound:4011487|FD-Score:8.17|P-value:1.73E-12 ID:SGTC_2013|Compound:4024628|FD-Score:4.00|P-value:3.44E-4 ID:SGTC_2021|Compound:4019055|FD-Score:5.07|P-value:8.38E-6 ID:SGTC_2036|Compound:5160441|FD-Score:4.83|P-value:2.06E-5 ID:SGTC_2046|Compound:4110841|FD-Score:3.97|P-value:3.87E-4 ID:SGTC_2059|Compound:5238311|FD-Score:-5.87|P-value:2.28E-7 ID:SGTC_2071|Compound:5230951|FD-Score:3.90|P-value:4.75E-4 ID:SGTC_2100|Compound:5377183|FD-Score:-5.25|P-value:3.12E-6 ID:SGTC_2248|Compound:tofa|FD-Score:5.96|P-value:2.07E-7 ID:SGTC_2257|Compound:7960413|FD-Score:4.89|P-value:1.63E-5 ID:SGTC_2275|Compound:7947463|FD-Score:5.93|P-value:2.28E-7 ID:SGTC_2291|Compound:7917025|FD-Score:9.30|P-value:1.19E-15 ID:SGTC_2309|Compound:7664088|FD-Score:6.32|P-value:3.85E-8 ID:SGTC_2322|Compound:7413319|FD-Score:7.71|P-value:2.72E-11 ID:SGTC_2359|Compound:9039622|FD-Score:10.80|P-value:1.22E-20 ID:SGTC_2360|Compound:9040895|FD-Score:6.04|P-value:1.43E-7 ID:SGTC_2374|Compound:9071832|FD-Score:6.80|P-value:3.64E-9 ID:SGTC_2380|Compound:9035439|FD-Score:9.31|P-value:1.11E-15 ID:SGTC_2389|Compound:9091542|FD-Score:6.63|P-value:8.65E-9 ID:SGTC_2418|Compound:pentamidine|FD-Score:4.20|P-value:1.86E-4 ID:SGTC_2450|Compound:5739737|FD-Score:-4.84|P-value:1.58E-5 ID:SGTC_2467|Compound:5474540|FD-Score:4.16|P-value:2.11E-4 ID:SGTC_2472|Compound:5377652|FD-Score:5.08|P-value:8.17E-6 ID:SGTC_2499|Compound:avocadenofuran|FD-Score:3.85|P-value:5.49E-4 ID:SGTC_2504|Compound:purpurogallin|FD-Score:5.69|P-value:6.57E-7 ID:SGTC_2516|Compound:gossypol|FD-Score:3.80|P-value:6.35E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.68|P-value:6.84E-7 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:4.08|P-value:2.74E-4 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:-4.23|P-value:1.35E-4 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:6.19|P-value:6.97E-8 ID:SGTC_2582|Compound:agaric acid|FD-Score:8.53|P-value:1.88E-13 ID:SGTC_2586|Compound:curcumin|FD-Score:5.36|P-value:2.60E-6 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:5.86|P-value:3.22E-7 ID:SGTC_2619|Compound:obliquin|FD-Score:5.81|P-value:4.03E-7 ID:SGTC_2638|Compound:epoxomicin|FD-Score:4.03|P-value:3.15E-4 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:7.79|P-value:1.65E-11 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:4.11|P-value:2.43E-4 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.42|P-value:1.37E-10 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:20.80|P-value:7.92E-71 ID:SGTC_2737|Compound:bleomycin|FD-Score:15.20|P-value:1.41E-38 ID:SGTC_2751|Compound:anetholtrithion|FD-Score:-4.17|P-value:1.63E-4 ID:SGTC_2757|Compound:clomiphene|FD-Score:-3.78|P-value:5.62E-4 ID:SGTC_2779|Compound:methotrexate|FD-Score:4.15|P-value:2.16E-4 ID:SGTC_2790|Compound:5423970|FD-Score:4.22|P-value:1.74E-4 ID:SGTC_2859|Compound:9028643|FD-Score:3.91|P-value:4.65E-4 ID:SGTC_2924|Compound:9010168|FD-Score:3.86|P-value:5.30E-4 ID:SGTC_2955|Compound:9076254|FD-Score:5.11|P-value:7.28E-6 ID:SGTC_2956|Compound:9076196|FD-Score:-4.18|P-value:1.57E-4 ID:SGTC_2961|Compound:9083290|FD-Score:-4.03|P-value:2.61E-4 ID:SGTC_2973|Compound:9094665|FD-Score:5.29|P-value:3.46E-6 ID:SGTC_2981|Compound:9013952|FD-Score:5.55|P-value:1.21E-6 ID:SGTC_3037|Compound:9091026|FD-Score:7.81|P-value:1.47E-11 ID:SGTC_3078|Compound:9116413|FD-Score:5.01|P-value:1.04E-5 ID:SGTC_3114|Compound:9122766|FD-Score:3.75|P-value:7.54E-4 ID:SGTC_3152|Compound:9099253|FD-Score:13.40|P-value:1.47E-30 ID:SGTC_3166|Compound:9102297|FD-Score:3.68|P-value:9.08E-4 ID:SGTC_3218|Compound:9131285|FD-Score:10.40|P-value:3.20E-19 ID:SGTC_15|Compound:0266-0086|FD-Score:5.89|P-value:2.75E-7 ID:SGTC_40|Compound:0327-0103|FD-Score:-3.66|P-value:8.00E-4 ID:SGTC_57|Compound:miconazole|FD-Score:-3.82|P-value:5.00E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:-7.79|P-value:1.15E-11 ID:SGTC_103|Compound:0844-0104|FD-Score:3.99|P-value:3.61E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:11.40|P-value:1.87E-22 ID:SGTC_137|Compound:0438-0332|FD-Score:4.58|P-value:5.12E-5 ID:SGTC_164|Compound:4100-3994|FD-Score:6.09|P-value:1.11E-7 ID:SGTC_167|Compound:3672-0051|FD-Score:-3.90|P-value:3.85E-4 ID:SGTC_172|Compound:1112-0046|FD-Score:3.92|P-value:4.41E-4 ID:SGTC_206|Compound:4546-0025|FD-Score:29.00|P-value:2.86E-135 ID:SGTC_221|Compound:trifluoperazine|FD-Score:18.40|P-value:6.68E-56 ID:SGTC_232|Compound:clozapine|FD-Score:26.40|P-value:2.47E-112 ID:SGTC_245|Compound:methotrexate|FD-Score:7.24|P-value:3.60E-10 ID:SGTC_255|Compound:tunicamycin|FD-Score:11.90|P-value:2.25E-24 ID:SGTC_263|Compound:alizarin|FD-Score:6.49|P-value:1.73E-8 ID:SGTC_266|Compound:formosanin C|FD-Score:-4.18|P-value:1.61E-4 ID:SGTC_278|Compound:4092-0821|FD-Score:-3.97|P-value:3.15E-4 ID:SGTC_297|Compound:0986-0032|FD-Score:-3.61|P-value:9.29E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:28.10|P-value:8.41E-128 ID:SGTC_304|Compound:1310-0298|FD-Score:-5.28|P-value:2.86E-6 ID:SGTC_309|Compound:k408-0051|FD-Score:-3.93|P-value:3.51E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.88|P-value:1.36E-5 ID:SGTC_313|Compound:3474-0040|FD-Score:7.82|P-value:1.43E-11 ID:SGTC_314|Compound:1671-0008|FD-Score:-3.68|P-value:7.45E-4 ID:SGTC_315|Compound:k915-0449|FD-Score:4.88|P-value:1.70E-5 ID:SGTC_337|Compound:1315-0038|FD-Score:13.00|P-value:1.03E-28 ID:SGTC_339|Compound:3091-4833|FD-Score:4.54|P-value:5.89E-5 ID:SGTC_352|Compound:k048-0007|FD-Score:6.52|P-value:1.49E-8 ID:SGTC_364|Compound:0083-0097|FD-Score:-4.21|P-value:1.42E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:4.23|P-value:1.65E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:6.63|P-value:8.47E-9 ID:SGTC_443|Compound:clozapine|FD-Score:4.81|P-value:2.19E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:9.53|P-value:2.48E-16 ID:SGTC_447|Compound:ml7|FD-Score:5.51|P-value:1.43E-6 ID:SGTC_449|Compound:xestospongin c|FD-Score:8.52|P-value:2.06E-13 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-7.69|P-value:2.07E-11 ID:SGTC_455|Compound:paf C-16|FD-Score:-4.54|P-value:4.69E-5 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:4.03|P-value:3.20E-4 ID:SGTC_528|Compound:3492-0019|FD-Score:16.30|P-value:1.77E-44 ID:SGTC_535|Compound:2293-4129|FD-Score:31.00|P-value:3.50E-154 ID:SGTC_561|Compound:1550-0330|FD-Score:-3.72|P-value:6.75E-4 ID:SGTC_568|Compound:1193-0097|FD-Score:7.12|P-value:6.90E-10 ID:SGTC_577|Compound:r071-0003|FD-Score:4.37|P-value:1.07E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:4.51|P-value:6.53E-5 ID:SGTC_607|Compound:4491-0986|FD-Score:4.25|P-value:1.55E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:6.78|P-value:4.00E-9 ID:SGTC_690|Compound:glyoxal|FD-Score:-3.95|P-value:3.37E-4 ID:SGTC_692|Compound:k241-0027|FD-Score:6.40|P-value:2.61E-8 ID:SGTC_697|Compound:0508-1955|FD-Score:14.70|P-value:1.61E-36 ID:SGTC_711|Compound:k292-0785|FD-Score:-6.38|P-value:2.09E-8 ID:SGTC_754|Compound:3474-0146|FD-Score:5.33|P-value:2.94E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:5.12|P-value:6.89E-6 ID:SGTC_794|Compound:k038-0031|FD-Score:5.76|P-value:4.98E-7 ID:SGTC_805|Compound:3852-0218|FD-Score:4.82|P-value:2.14E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:-3.87|P-value:4.31E-4 ID:SGTC_875|Compound:0709-0210|FD-Score:5.34|P-value:2.88E-6 ID:SGTC_888|Compound:0916-0002|FD-Score:11.80|P-value:4.31E-24 ID:SGTC_900|Compound:1112-0045|FD-Score:9.53|P-value:2.44E-16 ID:SGTC_940|Compound:3232-1287|FD-Score:7.06|P-value:9.63E-10 ID:SGTC_955|Compound:1216-0110|FD-Score:3.67|P-value:9.35E-4 ID:SGTC_987|Compound:1497-1013|FD-Score:5.97|P-value:1.96E-7 ID:SGTC_993|Compound:3909-8757|FD-Score:8.24|P-value:1.16E-12 ID:SGTC_997|Compound:3996-0078|FD-Score:3.97|P-value:3.78E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:6.83|P-value:3.07E-9 ID:SGTC_1049|Compound:3226-0134|FD-Score:3.65|P-value:9.99E-4 ID:SGTC_1071|Compound:trifluoperazine|FD-Score:5.98|P-value:1.82E-7 ID:SGTC_1081|Compound:sertraline|FD-Score:7.72|P-value:2.50E-11 ID:SGTC_1103|Compound:duloxetine|FD-Score:4.03|P-value:3.16E-4 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:8.97|P-value:1.09E-14 ID:SGTC_1130|Compound:3454-2858|FD-Score:8.62|P-value:1.05E-13 ID:SGTC_1161|Compound:k007-0610|FD-Score:3.66|P-value:9.75E-4 ID:SGTC_1174|Compound:0739-0097|FD-Score:5.49|P-value:1.57E-6 ID:SGTC_1253|Compound:0550-0034|FD-Score:3.89|P-value:4.94E-4 ID:SGTC_1254|Compound:0550-0035|FD-Score:3.82|P-value:6.13E-4 ID:SGTC_1257|Compound:0669-0121|FD-Score:3.73|P-value:7.84E-4 ID:SGTC_1262|Compound:0737-0114|FD-Score:3.82|P-value:6.05E-4 ID:SGTC_1394|Compound:3474-0001|FD-Score:8.68|P-value:7.18E-14 ID:SGTC_1495|Compound:4469-0029|FD-Score:6.75|P-value:4.65E-9 ID:SGTC_1522|Compound:st012842|FD-Score:-3.60|P-value:9.57E-4 ID:SGTC_1547|Compound:harmine|FD-Score:9.79|P-value:3.68E-17 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.93|P-value:4.38E-4 ID:SGTC_1612|Compound:st002233|FD-Score:4.51|P-value:6.44E-5 ID:SGTC_1658|Compound:st012944|FD-Score:6.59|P-value:1.07E-8 ID:SGTC_1665|Compound:st014639|FD-Score:6.65|P-value:7.65E-9 ID:SGTC_1750|Compound:st081859|FD-Score:9.86|P-value:2.23E-17 ID:SGTC_1754|Compound:st042065|FD-Score:6.89|P-value:2.30E-9 ID:SGTC_1760|Compound:st045453|FD-Score:11.00|P-value:2.49E-21 ID:SGTC_1781|Compound:st038725|FD-Score:25.90|P-value:6.35E-109 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:4.60|P-value:4.69E-5 ID:SGTC_1789|Compound:tunicamycin|FD-Score:10.10|P-value:3.38E-18 ID:SGTC_1797|Compound:st048695|FD-Score:5.44|P-value:1.91E-6 ID:SGTC_1803|Compound:st050068|FD-Score:6.38|P-value:2.94E-8 ID:SGTC_1810|Compound:st050138|FD-Score:3.72|P-value:8.14E-4 ID:SGTC_1920|Compound:st075728|FD-Score:5.08|P-value:7.94E-6 ID:SGTC_1921|Compound:5740136|FD-Score:-3.62|P-value:9.00E-4 ID:SGTC_1926|Compound:methyl fluorone black|FD-Score:7.34|P-value:2.16E-10 ID:SGTC_1933|Compound:st074711|FD-Score:7.24|P-value:3.64E-10 ID:SGTC_1991|Compound:st073000|FD-Score:9.75|P-value:4.98E-17 ID:SGTC_2006|Compound:4011487|FD-Score:8.17|P-value:1.73E-12 ID:SGTC_2013|Compound:4024628|FD-Score:4.00|P-value:3.44E-4 ID:SGTC_2021|Compound:4019055|FD-Score:5.07|P-value:8.38E-6 ID:SGTC_2036|Compound:5160441|FD-Score:4.83|P-value:2.06E-5 ID:SGTC_2046|Compound:4110841|FD-Score:3.97|P-value:3.87E-4 ID:SGTC_2059|Compound:5238311|FD-Score:-5.87|P-value:2.28E-7 ID:SGTC_2071|Compound:5230951|FD-Score:3.90|P-value:4.75E-4 ID:SGTC_2100|Compound:5377183|FD-Score:-5.25|P-value:3.12E-6 ID:SGTC_2248|Compound:tofa|FD-Score:5.96|P-value:2.07E-7 ID:SGTC_2257|Compound:7960413|FD-Score:4.89|P-value:1.63E-5 ID:SGTC_2275|Compound:7947463|FD-Score:5.93|P-value:2.28E-7 ID:SGTC_2291|Compound:7917025|FD-Score:9.30|P-value:1.19E-15 ID:SGTC_2309|Compound:7664088|FD-Score:6.32|P-value:3.85E-8 ID:SGTC_2322|Compound:7413319|FD-Score:7.71|P-value:2.72E-11 ID:SGTC_2359|Compound:9039622|FD-Score:10.80|P-value:1.22E-20 ID:SGTC_2360|Compound:9040895|FD-Score:6.04|P-value:1.43E-7 ID:SGTC_2374|Compound:9071832|FD-Score:6.80|P-value:3.64E-9 ID:SGTC_2380|Compound:9035439|FD-Score:9.31|P-value:1.11E-15 ID:SGTC_2389|Compound:9091542|FD-Score:6.63|P-value:8.65E-9 ID:SGTC_2418|Compound:pentamidine|FD-Score:4.20|P-value:1.86E-4 ID:SGTC_2450|Compound:5739737|FD-Score:-4.84|P-value:1.58E-5 ID:SGTC_2467|Compound:5474540|FD-Score:4.16|P-value:2.11E-4 ID:SGTC_2472|Compound:5377652|FD-Score:5.08|P-value:8.17E-6 ID:SGTC_2499|Compound:avocadenofuran|FD-Score:3.85|P-value:5.49E-4 ID:SGTC_2504|Compound:purpurogallin|FD-Score:5.69|P-value:6.57E-7 ID:SGTC_2516|Compound:gossypol|FD-Score:3.80|P-value:6.35E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.68|P-value:6.84E-7 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:4.08|P-value:2.74E-4 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:-4.23|P-value:1.35E-4 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:6.19|P-value:6.97E-8 ID:SGTC_2582|Compound:agaric acid|FD-Score:8.53|P-value:1.88E-13 ID:SGTC_2586|Compound:curcumin|FD-Score:5.36|P-value:2.60E-6 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:5.86|P-value:3.22E-7 ID:SGTC_2619|Compound:obliquin|FD-Score:5.81|P-value:4.03E-7 ID:SGTC_2638|Compound:epoxomicin|FD-Score:4.03|P-value:3.15E-4 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:7.79|P-value:1.65E-11 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:4.11|P-value:2.43E-4 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.42|P-value:1.37E-10 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:20.80|P-value:7.92E-71 ID:SGTC_2737|Compound:bleomycin|FD-Score:15.20|P-value:1.41E-38 ID:SGTC_2751|Compound:anetholtrithion|FD-Score:-4.17|P-value:1.63E-4 ID:SGTC_2757|Compound:clomiphene|FD-Score:-3.78|P-value:5.62E-4 ID:SGTC_2779|Compound:methotrexate|FD-Score:4.15|P-value:2.16E-4 ID:SGTC_2790|Compound:5423970|FD-Score:4.22|P-value:1.74E-4 ID:SGTC_2859|Compound:9028643|FD-Score:3.91|P-value:4.65E-4 ID:SGTC_2924|Compound:9010168|FD-Score:3.86|P-value:5.30E-4 ID:SGTC_2955|Compound:9076254|FD-Score:5.11|P-value:7.28E-6 ID:SGTC_2956|Compound:9076196|FD-Score:-4.18|P-value:1.57E-4 ID:SGTC_2961|Compound:9083290|FD-Score:-4.03|P-value:2.61E-4 ID:SGTC_2973|Compound:9094665|FD-Score:5.29|P-value:3.46E-6 ID:SGTC_2981|Compound:9013952|FD-Score:5.55|P-value:1.21E-6 ID:SGTC_3037|Compound:9091026|FD-Score:7.81|P-value:1.47E-11 ID:SGTC_3078|Compound:9116413|FD-Score:5.01|P-value:1.04E-5 ID:SGTC_3114|Compound:9122766|FD-Score:3.75|P-value:7.54E-4 ID:SGTC_3152|Compound:9099253|FD-Score:13.40|P-value:1.47E-30 ID:SGTC_3166|Compound:9102297|FD-Score:3.68|P-value:9.08E-4 ID:SGTC_3218|Compound:9131285|FD-Score:10.40|P-value:3.20E-19

Top fitness defect scores for YDR455C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_535 2293-4129 31.00 48.2 µM 3.50E-154 NEO1 1 1.14E-210
2 SGTC_206 4546-0025 29.00 72.0 µM 2.86E-135 NEO1 1 9.32E-185
3 SGTC_301 4119-0100 28.10 24.5 µM 8.41E-128 NEO1 1 1.59E-174
4 SGTC_232 clozapine 26.40 119.0 µM 2.47E-112 NEO1 1 2.48E-153
5 SGTC_1781 st038725 25.90 66.3 µM 6.35E-109 NEO1 1 1.17E-148
6 SGTC_2697 mebhydrolin 20.80 72.4 µM 7.92E-71 NEO1 3 1.84E-96
7 SGTC_221 trifluoperazine 18.40 10.3 µM 6.68E-56 NEO1-PIK1 13 5.19E-76
8 SGTC_528 3492-0019 16.30 172.0 µM 1.77E-44 calcium & mitochondrial duress 8 2.33E-60
9 SGTC_2737 bleomycin 15.20 30.5 nM 1.41E-38 Golgi 6 2.82E-52
10 SGTC_697 0508-1955 14.70 564.0 µM 1.61E-36 1 1.86E-49
11 SGTC_3152 9099253 13.40 49.5 µM 1.47E-30 NEO1-PIK1 9 2.71E-41
12 SGTC_337 1315-0038 13.00 354.0 µM 1.03E-28 amide catabolism 2 9.14E-39
13 SGTC_255 tunicamycin 11.90 200.5 nM 2.25E-24 unfolded protein response 9 8.05E-33
14 SGTC_888 0916-0002 11.80 7.0 µM 4.31E-24 NEO1 5 1.96E-32
15 SGTC_117 lucigenin 11.40 22.1 µM 1.87E-22 redox potentiating 4 3.43E-30
16 SGTC_1760 st045453 11.00 10.4 µM 2.49E-21 NEO1-PIK1 26 1.18E-28
17 SGTC_2359 9039622 10.80 200.0 µM 1.22E-20 endomembrane recycling 1 1.05E-27
18 SGTC_3218 9131285 10.40 49.5 µM 3.20E-19 endomembrane recycling 3 9.11E-26
19 SGTC_1789 tunicamycin 10.10 25.0 nM 3.38E-18 unfolded protein response 6 2.30E-24
20 SGTC_1750 st081859 9.86 2.4 µM 2.23E-17 endomembrane recycling 45 3.04E-23

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.750 0 YDR456W NHX1 hom Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion
0.581 8.22E-303 YJL154C VPS35 hom Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p
0.557 2.41E-272 YIL048W NEO1 het Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
0.555 9.09E-271 YJL053W PEP8 hom Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress
0.545 7.06E-259 YHR012W VPS29 hom Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval
0.494 8.54E-206 YOR039W CKB2 hom Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase
0.470 1.67E-183 YHR004C NEM1 hom Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard
0.459 7.15E-174 YDR372C VPS74 hom Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33
0.450 3.69E-167 YAL009W SPO7 hom Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation
0.435 4.24E-155 YLR025W SNF7 hom One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes
0.432 1.20E-152 YOR293W RPS10A hom Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10A has a paralog, RPS10B, that arose from the whole genome duplication
0.428 2.31E-149 YJL124C LSM1 hom Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; forms cytoplasmic foci upon DNA replication stress
0.383 1.16E-117 YGL019W CKB1 hom Beta regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
0.381 1.92E-115 YDL090C RAM1 hom Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit
0.366 1.18E-106 YJL204C RCY1 hom F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth