YER003C / PMI40

Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation

Zygosity: Heterozygous strain
fixedexpanded
Profile for YER003C / PMI40

Click on Significant Values for Screen Details ID:SGTC_4|Compound:0960-0234|FD-Score:3.30|P-value:5.01E-4 ID:SGTC_125|Compound:0133-0007|FD-Score:3.24|P-value:6.07E-4 ID:SGTC_142|Compound:0335-0849|FD-Score:-3.66|P-value:1.46E-4 ID:SGTC_143|Compound:4032-1194|FD-Score:3.24|P-value:6.08E-4 ID:SGTC_145|Compound:3737-0113|FD-Score:3.51|P-value:2.34E-4 ID:SGTC_166|Compound:k072-0058|FD-Score:3.42|P-value:3.25E-4 ID:SGTC_342|Compound:k048-0088|FD-Score:3.69|P-value:1.18E-4 ID:SGTC_347|Compound:4534-1311|FD-Score:3.97|P-value:3.77E-5 ID:SGTC_370|Compound:0180-0345|FD-Score:3.44|P-value:2.97E-4 ID:SGTC_398|Compound:bronopol|FD-Score:4.62|P-value:2.03E-6 ID:SGTC_412|Compound:gemfibrozil|FD-Score:5.38|P-value:4.13E-8 ID:SGTC_468|Compound:gf-109203x|FD-Score:3.36|P-value:4.10E-4 ID:SGTC_469|Compound:w7|FD-Score:3.28|P-value:5.40E-4 ID:SGTC_470|Compound:aa-861|FD-Score:5.85|P-value:2.85E-9 ID:SGTC_471|Compound:1-acyl-paf|FD-Score:6.56|P-value:3.19E-11 ID:SGTC_507|Compound:nimesulide|FD-Score:3.27|P-value:5.59E-4 ID:SGTC_511|Compound:blebbistatin|FD-Score:3.76|P-value:8.99E-5 ID:SGTC_512|Compound:prima-1|FD-Score:5.95|P-value:1.53E-9 ID:SGTC_513|Compound:4245-1575|FD-Score:3.40|P-value:3.45E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:4.32|P-value:8.19E-6 ID:SGTC_557|Compound:1315-0110|FD-Score:-4.15|P-value:1.93E-5 ID:SGTC_561|Compound:1550-0330|FD-Score:3.89|P-value:5.31E-5 ID:SGTC_633|Compound:0437-0093|FD-Score:3.94|P-value:4.29E-5 ID:SGTC_660|Compound:4031-1742|FD-Score:4.03|P-value:2.89E-5 ID:SGTC_679|Compound:0422-0091|FD-Score:7.12|P-value:6.97E-13 ID:SGTC_682|Compound:0kpi-0099|FD-Score:3.40|P-value:3.52E-4 ID:SGTC_700|Compound:3453-2283|FD-Score:5.11|P-value:1.75E-7 ID:SGTC_711|Compound:k292-0785|FD-Score:3.80|P-value:7.65E-5 ID:SGTC_836|Compound:0330-0104|FD-Score:5.00|P-value:3.11E-7 ID:SGTC_858|Compound:0438-0351|FD-Score:6.30|P-value:1.80E-10 ID:SGTC_867|Compound:0518-0118|FD-Score:8.37|P-value:4.12E-17 ID:SGTC_872|Compound:0588-0139|FD-Score:4.63|P-value:2.01E-6 ID:SGTC_911|Compound:3456-4043|FD-Score:6.48|P-value:5.58E-11 ID:SGTC_954|Compound:1189-0853|FD-Score:3.28|P-value:5.44E-4 ID:SGTC_990|Compound:3985-0011|FD-Score:3.28|P-value:5.36E-4 ID:SGTC_1128|Compound:3448-9350|FD-Score:5.05|P-value:2.46E-7 ID:SGTC_1190|Compound:1486-1332|FD-Score:5.09|P-value:2.00E-7 ID:SGTC_1208|Compound:2323-2347|FD-Score:-3.29|P-value:5.53E-4 ID:SGTC_1220|Compound:1838-0075|FD-Score:3.65|P-value:1.39E-4 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.39|P-value:6.14E-6 ID:SGTC_1415|Compound:3966-0071|FD-Score:4.65|P-value:1.82E-6 ID:SGTC_1459|Compound:k035-0031|FD-Score:4.19|P-value:1.51E-5 ID:SGTC_1465|Compound:k213-0056|FD-Score:3.92|P-value:4.65E-5 ID:SGTC_1533|Compound:dihydroergotamine mesylate|FD-Score:3.25|P-value:5.95E-4 ID:SGTC_1626|Compound:st003712|FD-Score:3.83|P-value:6.79E-5 ID:SGTC_1732|Compound:st034308|FD-Score:5.27|P-value:7.61E-8 ID:SGTC_1755|Compound:st041960|FD-Score:-3.14|P-value:9.39E-4 ID:SGTC_1854|Compound:st056233|FD-Score:3.65|P-value:1.40E-4 ID:SGTC_1914|Compound:st062367|FD-Score:4.48|P-value:3.98E-6 ID:SGTC_1919|Compound:st067113|FD-Score:-3.21|P-value:7.38E-4 ID:SGTC_1943|Compound:st076331|FD-Score:4.33|P-value:7.85E-6 ID:SGTC_1947|Compound:st076332|FD-Score:5.53|P-value:1.85E-8 ID:SGTC_2018|Compound:5133068|FD-Score:3.43|P-value:3.13E-4 ID:SGTC_2098|Compound:5376439|FD-Score:4.77|P-value:9.99E-7 ID:SGTC_2128|Compound:5255449|FD-Score:3.24|P-value:6.12E-4 ID:SGTC_2308|Compound:7584454|FD-Score:4.00|P-value:3.28E-5 ID:SGTC_2311|Compound:7694451|FD-Score:6.13|P-value:5.33E-10 ID:SGTC_2312|Compound:7706453|FD-Score:3.92|P-value:4.72E-5 ID:SGTC_2321|Compound:7390090|FD-Score:-4.90|P-value:5.84E-7 ID:SGTC_2345|Compound:9052315|FD-Score:3.15|P-value:8.30E-4 ID:SGTC_2349|Compound:9023730|FD-Score:-3.61|P-value:1.77E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-3.17|P-value:8.35E-4 ID:SGTC_2365|Compound:9042475|FD-Score:5.73|P-value:5.77E-9 ID:SGTC_2422|Compound:chlorphenesin carbamate|FD-Score:4.03|P-value:3.01E-5 ID:SGTC_2489|Compound:cantharidin|FD-Score:3.38|P-value:3.74E-4 ID:SGTC_2536|Compound:dehydroabietamide|FD-Score:3.90|P-value:5.06E-5 ID:SGTC_2604|Compound:4'-hydroxychalcone|FD-Score:6.18|P-value:3.72E-10 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.02|P-value:3.08E-5 ID:SGTC_2666|Compound:tannic acid|FD-Score:5.62|P-value:1.06E-8 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:3.44|P-value:3.00E-4 ID:SGTC_2706|Compound:st078239|FD-Score:4.81|P-value:8.21E-7 ID:SGTC_2768|Compound:sulfasalazine|FD-Score:6.18|P-value:3.81E-10 ID:SGTC_2800|Compound:7887935|FD-Score:-3.19|P-value:8.02E-4 ID:SGTC_2832|Compound:7992762|FD-Score:8.84|P-value:6.82E-19 ID:SGTC_2834|Compound:9001755|FD-Score:6.18|P-value:3.72E-10 ID:SGTC_2837|Compound:9008476|FD-Score:-4.20|P-value:1.59E-5 ID:SGTC_2844|Compound:9010103|FD-Score:-4.57|P-value:2.95E-6 ID:SGTC_2857|Compound:9024691|FD-Score:-3.23|P-value:6.87E-4 ID:SGTC_2964|Compound:9083345|FD-Score:-3.15|P-value:9.11E-4 ID:SGTC_3040|Compound:9091894|FD-Score:5.15|P-value:1.42E-7 ID:SGTC_3044|Compound:9093193|FD-Score:3.59|P-value:1.72E-4 ID:SGTC_3122|Compound:9126309|FD-Score:3.19|P-value:7.27E-4 ID:SGTC_3140|Compound:9094243|FD-Score:4.70|P-value:1.43E-6 ID:SGTC_3146|Compound:9095609|FD-Score:-3.21|P-value:7.35E-4 ID:SGTC_3225|Compound:9130819|FD-Score:4.70|P-value:1.45E-6 ID:SGTC_3242|Compound:9133940|FD-Score:3.61|P-value:1.61E-4 ID:SGTC_3253|Compound:9135987|FD-Score:4.40|P-value:5.91E-6 ID:SGTC_3310|Compound:9130229|FD-Score:3.63|P-value:1.48E-4 ID:SGTC_4|Compound:0960-0234|FD-Score:3.30|P-value:5.01E-4 ID:SGTC_125|Compound:0133-0007|FD-Score:3.24|P-value:6.07E-4 ID:SGTC_142|Compound:0335-0849|FD-Score:-3.66|P-value:1.46E-4 ID:SGTC_143|Compound:4032-1194|FD-Score:3.24|P-value:6.08E-4 ID:SGTC_145|Compound:3737-0113|FD-Score:3.51|P-value:2.34E-4 ID:SGTC_166|Compound:k072-0058|FD-Score:3.42|P-value:3.25E-4 ID:SGTC_342|Compound:k048-0088|FD-Score:3.69|P-value:1.18E-4 ID:SGTC_347|Compound:4534-1311|FD-Score:3.97|P-value:3.77E-5 ID:SGTC_370|Compound:0180-0345|FD-Score:3.44|P-value:2.97E-4 ID:SGTC_398|Compound:bronopol|FD-Score:4.62|P-value:2.03E-6 ID:SGTC_412|Compound:gemfibrozil|FD-Score:5.38|P-value:4.13E-8 ID:SGTC_468|Compound:gf-109203x|FD-Score:3.36|P-value:4.10E-4 ID:SGTC_469|Compound:w7|FD-Score:3.28|P-value:5.40E-4 ID:SGTC_470|Compound:aa-861|FD-Score:5.85|P-value:2.85E-9 ID:SGTC_471|Compound:1-acyl-paf|FD-Score:6.56|P-value:3.19E-11 ID:SGTC_507|Compound:nimesulide|FD-Score:3.27|P-value:5.59E-4 ID:SGTC_511|Compound:blebbistatin|FD-Score:3.76|P-value:8.99E-5 ID:SGTC_512|Compound:prima-1|FD-Score:5.95|P-value:1.53E-9 ID:SGTC_513|Compound:4245-1575|FD-Score:3.40|P-value:3.45E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:4.32|P-value:8.19E-6 ID:SGTC_557|Compound:1315-0110|FD-Score:-4.15|P-value:1.93E-5 ID:SGTC_561|Compound:1550-0330|FD-Score:3.89|P-value:5.31E-5 ID:SGTC_633|Compound:0437-0093|FD-Score:3.94|P-value:4.29E-5 ID:SGTC_660|Compound:4031-1742|FD-Score:4.03|P-value:2.89E-5 ID:SGTC_679|Compound:0422-0091|FD-Score:7.12|P-value:6.97E-13 ID:SGTC_682|Compound:0kpi-0099|FD-Score:3.40|P-value:3.52E-4 ID:SGTC_700|Compound:3453-2283|FD-Score:5.11|P-value:1.75E-7 ID:SGTC_711|Compound:k292-0785|FD-Score:3.80|P-value:7.65E-5 ID:SGTC_836|Compound:0330-0104|FD-Score:5.00|P-value:3.11E-7 ID:SGTC_858|Compound:0438-0351|FD-Score:6.30|P-value:1.80E-10 ID:SGTC_867|Compound:0518-0118|FD-Score:8.37|P-value:4.12E-17 ID:SGTC_872|Compound:0588-0139|FD-Score:4.63|P-value:2.01E-6 ID:SGTC_911|Compound:3456-4043|FD-Score:6.48|P-value:5.58E-11 ID:SGTC_954|Compound:1189-0853|FD-Score:3.28|P-value:5.44E-4 ID:SGTC_990|Compound:3985-0011|FD-Score:3.28|P-value:5.36E-4 ID:SGTC_1128|Compound:3448-9350|FD-Score:5.05|P-value:2.46E-7 ID:SGTC_1190|Compound:1486-1332|FD-Score:5.09|P-value:2.00E-7 ID:SGTC_1208|Compound:2323-2347|FD-Score:-3.29|P-value:5.53E-4 ID:SGTC_1220|Compound:1838-0075|FD-Score:3.65|P-value:1.39E-4 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.39|P-value:6.14E-6 ID:SGTC_1415|Compound:3966-0071|FD-Score:4.65|P-value:1.82E-6 ID:SGTC_1459|Compound:k035-0031|FD-Score:4.19|P-value:1.51E-5 ID:SGTC_1465|Compound:k213-0056|FD-Score:3.92|P-value:4.65E-5 ID:SGTC_1533|Compound:dihydroergotamine mesylate|FD-Score:3.25|P-value:5.95E-4 ID:SGTC_1626|Compound:st003712|FD-Score:3.83|P-value:6.79E-5 ID:SGTC_1732|Compound:st034308|FD-Score:5.27|P-value:7.61E-8 ID:SGTC_1755|Compound:st041960|FD-Score:-3.14|P-value:9.39E-4 ID:SGTC_1854|Compound:st056233|FD-Score:3.65|P-value:1.40E-4 ID:SGTC_1914|Compound:st062367|FD-Score:4.48|P-value:3.98E-6 ID:SGTC_1919|Compound:st067113|FD-Score:-3.21|P-value:7.38E-4 ID:SGTC_1943|Compound:st076331|FD-Score:4.33|P-value:7.85E-6 ID:SGTC_1947|Compound:st076332|FD-Score:5.53|P-value:1.85E-8 ID:SGTC_2018|Compound:5133068|FD-Score:3.43|P-value:3.13E-4 ID:SGTC_2098|Compound:5376439|FD-Score:4.77|P-value:9.99E-7 ID:SGTC_2128|Compound:5255449|FD-Score:3.24|P-value:6.12E-4 ID:SGTC_2308|Compound:7584454|FD-Score:4.00|P-value:3.28E-5 ID:SGTC_2311|Compound:7694451|FD-Score:6.13|P-value:5.33E-10 ID:SGTC_2312|Compound:7706453|FD-Score:3.92|P-value:4.72E-5 ID:SGTC_2321|Compound:7390090|FD-Score:-4.90|P-value:5.84E-7 ID:SGTC_2345|Compound:9052315|FD-Score:3.15|P-value:8.30E-4 ID:SGTC_2349|Compound:9023730|FD-Score:-3.61|P-value:1.77E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-3.17|P-value:8.35E-4 ID:SGTC_2365|Compound:9042475|FD-Score:5.73|P-value:5.77E-9 ID:SGTC_2422|Compound:chlorphenesin carbamate|FD-Score:4.03|P-value:3.01E-5 ID:SGTC_2489|Compound:cantharidin|FD-Score:3.38|P-value:3.74E-4 ID:SGTC_2536|Compound:dehydroabietamide|FD-Score:3.90|P-value:5.06E-5 ID:SGTC_2604|Compound:4'-hydroxychalcone|FD-Score:6.18|P-value:3.72E-10 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.02|P-value:3.08E-5 ID:SGTC_2666|Compound:tannic acid|FD-Score:5.62|P-value:1.06E-8 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:3.44|P-value:3.00E-4 ID:SGTC_2706|Compound:st078239|FD-Score:4.81|P-value:8.21E-7 ID:SGTC_2768|Compound:sulfasalazine|FD-Score:6.18|P-value:3.81E-10 ID:SGTC_2800|Compound:7887935|FD-Score:-3.19|P-value:8.02E-4 ID:SGTC_2832|Compound:7992762|FD-Score:8.84|P-value:6.82E-19 ID:SGTC_2834|Compound:9001755|FD-Score:6.18|P-value:3.72E-10 ID:SGTC_2837|Compound:9008476|FD-Score:-4.20|P-value:1.59E-5 ID:SGTC_2844|Compound:9010103|FD-Score:-4.57|P-value:2.95E-6 ID:SGTC_2857|Compound:9024691|FD-Score:-3.23|P-value:6.87E-4 ID:SGTC_2964|Compound:9083345|FD-Score:-3.15|P-value:9.11E-4 ID:SGTC_3040|Compound:9091894|FD-Score:5.15|P-value:1.42E-7 ID:SGTC_3044|Compound:9093193|FD-Score:3.59|P-value:1.72E-4 ID:SGTC_3122|Compound:9126309|FD-Score:3.19|P-value:7.27E-4 ID:SGTC_3140|Compound:9094243|FD-Score:4.70|P-value:1.43E-6 ID:SGTC_3146|Compound:9095609|FD-Score:-3.21|P-value:7.35E-4 ID:SGTC_3225|Compound:9130819|FD-Score:4.70|P-value:1.45E-6 ID:SGTC_3242|Compound:9133940|FD-Score:3.61|P-value:1.61E-4 ID:SGTC_3253|Compound:9135987|FD-Score:4.40|P-value:5.91E-6 ID:SGTC_3310|Compound:9130229|FD-Score:3.63|P-value:1.48E-4

Top fitness defect scores for YER003C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_2832 7992762 8.84 52.0 µM 6.82E-19 1 4.67E-19 3.42
2 SGTC_867 0518-0118 8.37 155.0 µM 4.12E-17 DNA intercalators 2 2.96E-17 1.78
3 SGTC_679 0422-0091 7.12 41.4 µM 6.97E-13 Golgi 2 5.54E-13 1.02
4 SGTC_471 1-acyl-paf 6.56 4.0 µM 3.19E-11 DNA intercalators 6 2.63E-11 0.26
5 SGTC_911 3456-4043 6.48 236.0 µM 5.58E-11 mitochondrial processes 2 4.64E-11 0.81
6 SGTC_858 0438-0351 6.30 2.8 µM 1.80E-10 copper-dependent oxidative stress 1 1.51E-10 0.91
7 SGTC_2834 9001755 6.18 58.4 µM 3.72E-10 1 3.15E-10 1.25
8 SGTC_2604 4'-hydroxychalcone 6.18 11.3 µM 3.72E-10 2 3.15E-10 0.68
9 SGTC_2768 sulfasalazine 6.18 50.2 µM 3.81E-10 1 3.23E-10 0.80
10 SGTC_2311 7694451 6.13 200.0 µM 5.33E-10 1 4.53E-10 1.02
11 SGTC_512 prima-1 5.95 270.0 µM 1.53E-9 DNA intercalators 3 1.31E-9 0.78
12 SGTC_470 aa-861 5.85 153.0 µM 2.85E-9 sphingolipid biosynthesis & PDR1 5 2.47E-9 0.10
13 SGTC_2365 9042475 5.73 200.0 µM 5.77E-9 2 5.03E-9 0.72
14 SGTC_2666 tannic acid 5.62 100.0 µM 1.06E-8 iron homeostasis 6 9.32E-9 0.45
15 SGTC_1947 st076332 5.53 61.6 µM 1.85E-8 1 1.63E-8 1.61
16 SGTC_412 gemfibrozil 5.38 100.0 µM 4.13E-8 DNA intercalators 2 3.67E-8 0.79
17 SGTC_1732 st034308 5.27 51.8 µM 7.61E-8 2 6.80E-8 0.42
18 SGTC_3040 9091894 5.15 49.5 µM 1.42E-7 DNA intercalators 5 1.28E-7 0.04
19 SGTC_700 3453-2283 5.11 142.0 µM 1.75E-7 amide catabolism 2 1.57E-7 0.14
20 SGTC_1190 1486-1332 5.09 13.0 µM 2.00E-7 2 1.81E-7 0.82

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.369 4.71E-108 YMR119W ASI1 hom Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals; ASI1 has a paralog, ASI3, that arose from the whole genome duplication
0.357 2.45E-101 YMR208W ERG12 het Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
0.355 2.74E-100 YDL058W USO1 het Essential protein involved in the vesicle-mediated ER to Golgi transport step of secretion; binds membranes and functions during vesicle docking to the Golgi; required for assembly of the ER-to-Golgi SNARE complex
0.295 3.64E-68 YOR294W RRS1 het Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington's disease model mice
0.293 2.29E-67 YDR458C HEH2 hom Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle
0.290 5.50E-66 YNL317W PFS2 het Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex
0.285 1.39E-63 YOR278W HEM4 het Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria
0.271 1.35E-57 YDR060W MAK21 het Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein
0.270 5.64E-57 YGR156W PTI1 het Essential protein that is a component of CPF (cleavage and polyadenylation factor); involved in 3' end formation of snoRNA and mRNA; interacts directly with Pta1p; has similarity to mammalian Cleavage-Stimulation Factor CstF-64
0.252 9.07E-50 YDR362C TFC6 het One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110
0.250 4.32E-49 YKL139W CTK1 hom Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13
0.239 6.77E-45 YGL200C EMP24 hom Component of the p24 complex; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles
0.182 3.00E-26 YHR172W SPC97 het Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
0.177 6.47E-25 YJL085W EXO70 het Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress
0.160 1.59E-20 YGL023C PIB2 hom Protein of unknown function; contains FYVE domain; similar to Fab1 and Vps27