YER031C / YPT31

Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication

Zygosity: Homozygous strain
fixedexpanded
Profile for YER031C / YPT31

Click on Significant Values for Screen Details ID:SGTC_15|Compound:0266-0086|FD-Score:6.67|P-value:2.41E-8 ID:SGTC_57|Compound:miconazole|FD-Score:7.72|P-value:1.26E-10 ID:SGTC_112|Compound:phenothiazine|FD-Score:-4.09|P-value:3.24E-4 ID:SGTC_116|Compound:0155-0182|FD-Score:4.65|P-value:7.52E-5 ID:SGTC_123|Compound:0083-0120|FD-Score:-4.24|P-value:2.03E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:-4.15|P-value:2.68E-4 ID:SGTC_141|Compound:0443-0274|FD-Score:4.57|P-value:9.77E-5 ID:SGTC_152|Compound:4469-0003|FD-Score:-3.94|P-value:4.99E-4 ID:SGTC_167|Compound:3672-0051|FD-Score:4.74|P-value:5.45E-5 ID:SGTC_178|Compound:4092-0806|FD-Score:4.94|P-value:2.78E-5 ID:SGTC_181|Compound:1447-1644|FD-Score:6.23|P-value:1.74E-7 ID:SGTC_197|Compound:4544-0043|FD-Score:4.17|P-value:3.46E-4 ID:SGTC_201|Compound:4262-0159|FD-Score:8.64|P-value:7.11E-13 ID:SGTC_207|Compound:4185-0010|FD-Score:7.01|P-value:4.86E-9 ID:SGTC_217|Compound:ketoconazole|FD-Score:4.00|P-value:5.62E-4 ID:SGTC_218|Compound:alverine citrate|FD-Score:5.78|P-value:1.16E-6 ID:SGTC_221|Compound:trifluoperazine|FD-Score:4.80|P-value:4.54E-5 ID:SGTC_252|Compound:miconazole|FD-Score:4.75|P-value:5.32E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:5.15|P-value:1.33E-5 ID:SGTC_258|Compound:haloperidol|FD-Score:6.48|P-value:5.68E-8 ID:SGTC_260|Compound:nsc-65238|FD-Score:3.91|P-value:7.41E-4 ID:SGTC_262|Compound:fenpropimorph|FD-Score:6.11|P-value:2.89E-7 ID:SGTC_278|Compound:4092-0821|FD-Score:11.20|P-value:2.27E-20 ID:SGTC_288|Compound:1315-0019|FD-Score:6.23|P-value:1.72E-7 ID:SGTC_291|Compound:4130-1278|FD-Score:5.51|P-value:3.39E-6 ID:SGTC_294|Compound:k038-0071|FD-Score:4.14|P-value:3.79E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:5.27|P-value:8.42E-6 ID:SGTC_304|Compound:1310-0298|FD-Score:-4.18|P-value:2.43E-4 ID:SGTC_308|Compound:4092-1169|FD-Score:6.90|P-value:8.31E-9 ID:SGTC_312|Compound:4092-0653|FD-Score:9.40|P-value:6.25E-15 ID:SGTC_313|Compound:3474-0040|FD-Score:6.29|P-value:1.34E-7 ID:SGTC_320|Compound:4092-0846|FD-Score:6.63|P-value:2.87E-8 ID:SGTC_346|Compound:4513-0042|FD-Score:4.45|P-value:1.44E-4 ID:SGTC_391|Compound:gliotoxin|FD-Score:4.81|P-value:4.29E-5 ID:SGTC_435|Compound:c-PAF|FD-Score:-4.86|P-value:2.59E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:8.01|P-value:2.64E-11 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.02|P-value:2.07E-5 ID:SGTC_449|Compound:xestospongin c|FD-Score:7.56|P-value:2.94E-10 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-4.37|P-value:1.33E-4 ID:SGTC_459|Compound:nigericin|FD-Score:9.16|P-value:2.99E-14 ID:SGTC_500|Compound:h-89|FD-Score:4.63|P-value:7.87E-5 ID:SGTC_515|Compound:4092-1064|FD-Score:8.96|P-value:1.02E-13 ID:SGTC_568|Compound:1193-0097|FD-Score:5.11|P-value:1.50E-5 ID:SGTC_576|Compound:1073-0113|FD-Score:4.45|P-value:1.42E-4 ID:SGTC_577|Compound:r071-0003|FD-Score:7.05|P-value:4.02E-9 ID:SGTC_637|Compound:1181-0519|FD-Score:8.15|P-value:1.25E-11 ID:SGTC_649|Compound:1123-0311|FD-Score:7.52|P-value:3.64E-10 ID:SGTC_658|Compound:3253-0951|FD-Score:4.41|P-value:1.63E-4 ID:SGTC_669|Compound:0108-0021|FD-Score:7.02|P-value:4.60E-9 ID:SGTC_689|Compound:0833-0039|FD-Score:4.59|P-value:9.08E-5 ID:SGTC_768|Compound:0384-0033|FD-Score:18.50|P-value:2.57E-52 ID:SGTC_784|Compound:4579-0127|FD-Score:4.08|P-value:4.45E-4 ID:SGTC_788|Compound:1182-0090|FD-Score:19.80|P-value:1.16E-59 ID:SGTC_805|Compound:3852-0218|FD-Score:3.82|P-value:9.39E-4 ID:SGTC_813|Compound:k007-0158|FD-Score:4.98|P-value:2.39E-5 ID:SGTC_868|Compound:0527-0199|FD-Score:9.77|P-value:5.84E-16 ID:SGTC_875|Compound:0709-0210|FD-Score:11.20|P-value:2.31E-20 ID:SGTC_887|Compound:0885-0007|FD-Score:8.77|P-value:3.28E-13 ID:SGTC_954|Compound:1189-0853|FD-Score:9.65|P-value:1.26E-15 ID:SGTC_999|Compound:4022-0066|FD-Score:4.99|P-value:2.32E-5 ID:SGTC_1005|Compound:4092-0690|FD-Score:15.70|P-value:1.37E-38 ID:SGTC_1019|Compound:4262-0212|FD-Score:9.80|P-value:4.66E-16 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.46|P-value:4.30E-15 ID:SGTC_1081|Compound:sertraline|FD-Score:9.65|P-value:1.23E-15 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.14|P-value:3.69E-4 ID:SGTC_1089|Compound:terbinafine|FD-Score:5.27|P-value:8.46E-6 ID:SGTC_1130|Compound:3454-2858|FD-Score:6.64|P-value:2.82E-8 ID:SGTC_1160|Compound:4092-0570|FD-Score:6.19|P-value:2.13E-7 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.70|P-value:6.37E-5 ID:SGTC_1230|Compound:0170-0365|FD-Score:5.79|P-value:1.12E-6 ID:SGTC_1306|Compound:1185-0270|FD-Score:7.01|P-value:4.76E-9 ID:SGTC_1308|Compound:1187-1617|FD-Score:5.87|P-value:7.91E-7 ID:SGTC_1394|Compound:3474-0001|FD-Score:4.17|P-value:3.46E-4 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.04|P-value:5.00E-4 ID:SGTC_1504|Compound:k297-0033|FD-Score:4.04|P-value:5.09E-4 ID:SGTC_1547|Compound:harmine|FD-Score:5.09|P-value:1.61E-5 ID:SGTC_1581|Compound:himbacine|FD-Score:4.62|P-value:8.25E-5 ID:SGTC_1672|Compound:st016598|FD-Score:8.62|P-value:7.93E-13 ID:SGTC_1687|Compound:st020778|FD-Score:4.29|P-value:2.39E-4 ID:SGTC_1712|Compound:st032288|FD-Score:5.19|P-value:1.13E-5 ID:SGTC_1750|Compound:st081859|FD-Score:7.11|P-value:3.02E-9 ID:SGTC_1760|Compound:st045453|FD-Score:5.76|P-value:1.27E-6 ID:SGTC_1779|Compound:st039427|FD-Score:-5.29|P-value:5.31E-6 ID:SGTC_1781|Compound:st038725|FD-Score:14.10|P-value:3.84E-31 ID:SGTC_1787|Compound:fluconazole|FD-Score:5.41|P-value:5.07E-6 ID:SGTC_1797|Compound:st048695|FD-Score:12.40|P-value:1.38E-24 ID:SGTC_1801|Compound:st050089|FD-Score:3.97|P-value:6.23E-4 ID:SGTC_1803|Compound:st050068|FD-Score:4.78|P-value:4.91E-5 ID:SGTC_1826|Compound:st055655|FD-Score:7.40|P-value:7.03E-10 ID:SGTC_1907|Compound:st060210|FD-Score:4.12|P-value:4.03E-4 ID:SGTC_1915|Compound:st067105|FD-Score:5.23|P-value:9.83E-6 ID:SGTC_1991|Compound:st073000|FD-Score:4.27|P-value:2.54E-4 ID:SGTC_2006|Compound:4011487|FD-Score:18.70|P-value:8.93E-54 ID:SGTC_2021|Compound:4019055|FD-Score:4.54|P-value:1.09E-4 ID:SGTC_2028|Compound:5153890|FD-Score:5.90|P-value:7.13E-7 ID:SGTC_2036|Compound:5160441|FD-Score:8.54|P-value:1.30E-12 ID:SGTC_2038|Compound:4100038|FD-Score:9.06|P-value:5.64E-14 ID:SGTC_2046|Compound:4110841|FD-Score:5.40|P-value:5.10E-6 ID:SGTC_2050|Compound:5263056|FD-Score:7.05|P-value:3.89E-9 ID:SGTC_2068|Compound:5226020|FD-Score:4.40|P-value:1.67E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:4.91|P-value:3.12E-5 ID:SGTC_2257|Compound:7960413|FD-Score:4.55|P-value:1.06E-4 ID:SGTC_2376|Compound:9072922|FD-Score:-5.03|P-value:1.42E-5 ID:SGTC_2380|Compound:9035439|FD-Score:3.80|P-value:9.86E-4 ID:SGTC_2398|Compound:5228213|FD-Score:4.93|P-value:2.88E-5 ID:SGTC_2537|Compound:larixol|FD-Score:-5.83|P-value:6.34E-7 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:8.63|P-value:7.86E-13 ID:SGTC_2586|Compound:curcumin|FD-Score:7.01|P-value:4.87E-9 ID:SGTC_2589|Compound:lobaric acid|FD-Score:4.27|P-value:2.53E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:7.05|P-value:4.06E-9 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:-3.82|P-value:7.17E-4 ID:SGTC_2666|Compound:tannic acid|FD-Score:5.32|P-value:6.91E-6 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:4.12|P-value:3.97E-4 ID:SGTC_2694|Compound:st077685|FD-Score:4.10|P-value:4.24E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:6.06|P-value:3.57E-7 ID:SGTC_2724|Compound:maprotiline|FD-Score:5.04|P-value:1.96E-5 ID:SGTC_2725|Compound:haloperidol|FD-Score:10.40|P-value:6.62E-18 ID:SGTC_2733|Compound:amorolfine|FD-Score:4.76|P-value:5.12E-5 ID:SGTC_2735|Compound:sertaconazole|FD-Score:4.26|P-value:2.57E-4 ID:SGTC_2765|Compound:myclobutanil|FD-Score:5.25|P-value:9.09E-6 ID:SGTC_2777|Compound:climbazole|FD-Score:4.85|P-value:3.84E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:8.92|P-value:1.30E-13 ID:SGTC_2790|Compound:5423970|FD-Score:6.14|P-value:2.54E-7 ID:SGTC_2816|Compound:7982706|FD-Score:5.32|P-value:7.00E-6 ID:SGTC_2880|Compound:9042983|FD-Score:4.88|P-value:3.48E-5 ID:SGTC_2896|Compound:9052656|FD-Score:4.27|P-value:2.55E-4 ID:SGTC_2938|Compound:9059746|FD-Score:6.60|P-value:3.36E-8 ID:SGTC_2948|Compound:9070189|FD-Score:9.79|P-value:4.97E-16 ID:SGTC_2974|Compound:9094440|FD-Score:5.05|P-value:1.92E-5 ID:SGTC_2976|Compound:9009005|FD-Score:-4.30|P-value:1.68E-4 ID:SGTC_2981|Compound:9013952|FD-Score:5.50|P-value:3.54E-6 ID:SGTC_2993|Compound:9054257|FD-Score:20.30|P-value:6.33E-63 ID:SGTC_3018|Compound:9082602|FD-Score:3.81|P-value:9.71E-4 ID:SGTC_3033|Compound:9090887|FD-Score:5.24|P-value:9.52E-6 ID:SGTC_3071|Compound:9117417|FD-Score:3.96|P-value:6.40E-4 ID:SGTC_3081|Compound:9117243|FD-Score:6.19|P-value:2.10E-7 ID:SGTC_3126|Compound:9127922|FD-Score:10.10|P-value:6.27E-17 ID:SGTC_3152|Compound:9099253|FD-Score:5.71|P-value:1.54E-6 ID:SGTC_3195|Compound:9113082|FD-Score:-4.99|P-value:1.62E-5 ID:SGTC_3218|Compound:9131285|FD-Score:4.29|P-value:2.35E-4 ID:SGTC_3308|Compound:9128332|FD-Score:6.16|P-value:2.42E-7 ID:SGTC_3347|Compound:9188721|FD-Score:5.96|P-value:5.46E-7 ID:SGTC_15|Compound:0266-0086|FD-Score:6.67|P-value:2.41E-8 ID:SGTC_57|Compound:miconazole|FD-Score:7.72|P-value:1.26E-10 ID:SGTC_112|Compound:phenothiazine|FD-Score:-4.09|P-value:3.24E-4 ID:SGTC_116|Compound:0155-0182|FD-Score:4.65|P-value:7.52E-5 ID:SGTC_123|Compound:0083-0120|FD-Score:-4.24|P-value:2.03E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:-4.15|P-value:2.68E-4 ID:SGTC_141|Compound:0443-0274|FD-Score:4.57|P-value:9.77E-5 ID:SGTC_152|Compound:4469-0003|FD-Score:-3.94|P-value:4.99E-4 ID:SGTC_167|Compound:3672-0051|FD-Score:4.74|P-value:5.45E-5 ID:SGTC_178|Compound:4092-0806|FD-Score:4.94|P-value:2.78E-5 ID:SGTC_181|Compound:1447-1644|FD-Score:6.23|P-value:1.74E-7 ID:SGTC_197|Compound:4544-0043|FD-Score:4.17|P-value:3.46E-4 ID:SGTC_201|Compound:4262-0159|FD-Score:8.64|P-value:7.11E-13 ID:SGTC_207|Compound:4185-0010|FD-Score:7.01|P-value:4.86E-9 ID:SGTC_217|Compound:ketoconazole|FD-Score:4.00|P-value:5.62E-4 ID:SGTC_218|Compound:alverine citrate|FD-Score:5.78|P-value:1.16E-6 ID:SGTC_221|Compound:trifluoperazine|FD-Score:4.80|P-value:4.54E-5 ID:SGTC_252|Compound:miconazole|FD-Score:4.75|P-value:5.32E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:5.15|P-value:1.33E-5 ID:SGTC_258|Compound:haloperidol|FD-Score:6.48|P-value:5.68E-8 ID:SGTC_260|Compound:nsc-65238|FD-Score:3.91|P-value:7.41E-4 ID:SGTC_262|Compound:fenpropimorph|FD-Score:6.11|P-value:2.89E-7 ID:SGTC_278|Compound:4092-0821|FD-Score:11.20|P-value:2.27E-20 ID:SGTC_288|Compound:1315-0019|FD-Score:6.23|P-value:1.72E-7 ID:SGTC_291|Compound:4130-1278|FD-Score:5.51|P-value:3.39E-6 ID:SGTC_294|Compound:k038-0071|FD-Score:4.14|P-value:3.79E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:5.27|P-value:8.42E-6 ID:SGTC_304|Compound:1310-0298|FD-Score:-4.18|P-value:2.43E-4 ID:SGTC_308|Compound:4092-1169|FD-Score:6.90|P-value:8.31E-9 ID:SGTC_312|Compound:4092-0653|FD-Score:9.40|P-value:6.25E-15 ID:SGTC_313|Compound:3474-0040|FD-Score:6.29|P-value:1.34E-7 ID:SGTC_320|Compound:4092-0846|FD-Score:6.63|P-value:2.87E-8 ID:SGTC_346|Compound:4513-0042|FD-Score:4.45|P-value:1.44E-4 ID:SGTC_391|Compound:gliotoxin|FD-Score:4.81|P-value:4.29E-5 ID:SGTC_435|Compound:c-PAF|FD-Score:-4.86|P-value:2.59E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:8.01|P-value:2.64E-11 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.02|P-value:2.07E-5 ID:SGTC_449|Compound:xestospongin c|FD-Score:7.56|P-value:2.94E-10 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-4.37|P-value:1.33E-4 ID:SGTC_459|Compound:nigericin|FD-Score:9.16|P-value:2.99E-14 ID:SGTC_500|Compound:h-89|FD-Score:4.63|P-value:7.87E-5 ID:SGTC_515|Compound:4092-1064|FD-Score:8.96|P-value:1.02E-13 ID:SGTC_568|Compound:1193-0097|FD-Score:5.11|P-value:1.50E-5 ID:SGTC_576|Compound:1073-0113|FD-Score:4.45|P-value:1.42E-4 ID:SGTC_577|Compound:r071-0003|FD-Score:7.05|P-value:4.02E-9 ID:SGTC_637|Compound:1181-0519|FD-Score:8.15|P-value:1.25E-11 ID:SGTC_649|Compound:1123-0311|FD-Score:7.52|P-value:3.64E-10 ID:SGTC_658|Compound:3253-0951|FD-Score:4.41|P-value:1.63E-4 ID:SGTC_669|Compound:0108-0021|FD-Score:7.02|P-value:4.60E-9 ID:SGTC_689|Compound:0833-0039|FD-Score:4.59|P-value:9.08E-5 ID:SGTC_768|Compound:0384-0033|FD-Score:18.50|P-value:2.57E-52 ID:SGTC_784|Compound:4579-0127|FD-Score:4.08|P-value:4.45E-4 ID:SGTC_788|Compound:1182-0090|FD-Score:19.80|P-value:1.16E-59 ID:SGTC_805|Compound:3852-0218|FD-Score:3.82|P-value:9.39E-4 ID:SGTC_813|Compound:k007-0158|FD-Score:4.98|P-value:2.39E-5 ID:SGTC_868|Compound:0527-0199|FD-Score:9.77|P-value:5.84E-16 ID:SGTC_875|Compound:0709-0210|FD-Score:11.20|P-value:2.31E-20 ID:SGTC_887|Compound:0885-0007|FD-Score:8.77|P-value:3.28E-13 ID:SGTC_954|Compound:1189-0853|FD-Score:9.65|P-value:1.26E-15 ID:SGTC_999|Compound:4022-0066|FD-Score:4.99|P-value:2.32E-5 ID:SGTC_1005|Compound:4092-0690|FD-Score:15.70|P-value:1.37E-38 ID:SGTC_1019|Compound:4262-0212|FD-Score:9.80|P-value:4.66E-16 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.46|P-value:4.30E-15 ID:SGTC_1081|Compound:sertraline|FD-Score:9.65|P-value:1.23E-15 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.14|P-value:3.69E-4 ID:SGTC_1089|Compound:terbinafine|FD-Score:5.27|P-value:8.46E-6 ID:SGTC_1130|Compound:3454-2858|FD-Score:6.64|P-value:2.82E-8 ID:SGTC_1160|Compound:4092-0570|FD-Score:6.19|P-value:2.13E-7 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.70|P-value:6.37E-5 ID:SGTC_1230|Compound:0170-0365|FD-Score:5.79|P-value:1.12E-6 ID:SGTC_1306|Compound:1185-0270|FD-Score:7.01|P-value:4.76E-9 ID:SGTC_1308|Compound:1187-1617|FD-Score:5.87|P-value:7.91E-7 ID:SGTC_1394|Compound:3474-0001|FD-Score:4.17|P-value:3.46E-4 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.04|P-value:5.00E-4 ID:SGTC_1504|Compound:k297-0033|FD-Score:4.04|P-value:5.09E-4 ID:SGTC_1547|Compound:harmine|FD-Score:5.09|P-value:1.61E-5 ID:SGTC_1581|Compound:himbacine|FD-Score:4.62|P-value:8.25E-5 ID:SGTC_1672|Compound:st016598|FD-Score:8.62|P-value:7.93E-13 ID:SGTC_1687|Compound:st020778|FD-Score:4.29|P-value:2.39E-4 ID:SGTC_1712|Compound:st032288|FD-Score:5.19|P-value:1.13E-5 ID:SGTC_1750|Compound:st081859|FD-Score:7.11|P-value:3.02E-9 ID:SGTC_1760|Compound:st045453|FD-Score:5.76|P-value:1.27E-6 ID:SGTC_1779|Compound:st039427|FD-Score:-5.29|P-value:5.31E-6 ID:SGTC_1781|Compound:st038725|FD-Score:14.10|P-value:3.84E-31 ID:SGTC_1787|Compound:fluconazole|FD-Score:5.41|P-value:5.07E-6 ID:SGTC_1797|Compound:st048695|FD-Score:12.40|P-value:1.38E-24 ID:SGTC_1801|Compound:st050089|FD-Score:3.97|P-value:6.23E-4 ID:SGTC_1803|Compound:st050068|FD-Score:4.78|P-value:4.91E-5 ID:SGTC_1826|Compound:st055655|FD-Score:7.40|P-value:7.03E-10 ID:SGTC_1907|Compound:st060210|FD-Score:4.12|P-value:4.03E-4 ID:SGTC_1915|Compound:st067105|FD-Score:5.23|P-value:9.83E-6 ID:SGTC_1991|Compound:st073000|FD-Score:4.27|P-value:2.54E-4 ID:SGTC_2006|Compound:4011487|FD-Score:18.70|P-value:8.93E-54 ID:SGTC_2021|Compound:4019055|FD-Score:4.54|P-value:1.09E-4 ID:SGTC_2028|Compound:5153890|FD-Score:5.90|P-value:7.13E-7 ID:SGTC_2036|Compound:5160441|FD-Score:8.54|P-value:1.30E-12 ID:SGTC_2038|Compound:4100038|FD-Score:9.06|P-value:5.64E-14 ID:SGTC_2046|Compound:4110841|FD-Score:5.40|P-value:5.10E-6 ID:SGTC_2050|Compound:5263056|FD-Score:7.05|P-value:3.89E-9 ID:SGTC_2068|Compound:5226020|FD-Score:4.40|P-value:1.67E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:4.91|P-value:3.12E-5 ID:SGTC_2257|Compound:7960413|FD-Score:4.55|P-value:1.06E-4 ID:SGTC_2376|Compound:9072922|FD-Score:-5.03|P-value:1.42E-5 ID:SGTC_2380|Compound:9035439|FD-Score:3.80|P-value:9.86E-4 ID:SGTC_2398|Compound:5228213|FD-Score:4.93|P-value:2.88E-5 ID:SGTC_2537|Compound:larixol|FD-Score:-5.83|P-value:6.34E-7 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:8.63|P-value:7.86E-13 ID:SGTC_2586|Compound:curcumin|FD-Score:7.01|P-value:4.87E-9 ID:SGTC_2589|Compound:lobaric acid|FD-Score:4.27|P-value:2.53E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:7.05|P-value:4.06E-9 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:-3.82|P-value:7.17E-4 ID:SGTC_2666|Compound:tannic acid|FD-Score:5.32|P-value:6.91E-6 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:4.12|P-value:3.97E-4 ID:SGTC_2694|Compound:st077685|FD-Score:4.10|P-value:4.24E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:6.06|P-value:3.57E-7 ID:SGTC_2724|Compound:maprotiline|FD-Score:5.04|P-value:1.96E-5 ID:SGTC_2725|Compound:haloperidol|FD-Score:10.40|P-value:6.62E-18 ID:SGTC_2733|Compound:amorolfine|FD-Score:4.76|P-value:5.12E-5 ID:SGTC_2735|Compound:sertaconazole|FD-Score:4.26|P-value:2.57E-4 ID:SGTC_2765|Compound:myclobutanil|FD-Score:5.25|P-value:9.09E-6 ID:SGTC_2777|Compound:climbazole|FD-Score:4.85|P-value:3.84E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:8.92|P-value:1.30E-13 ID:SGTC_2790|Compound:5423970|FD-Score:6.14|P-value:2.54E-7 ID:SGTC_2816|Compound:7982706|FD-Score:5.32|P-value:7.00E-6 ID:SGTC_2880|Compound:9042983|FD-Score:4.88|P-value:3.48E-5 ID:SGTC_2896|Compound:9052656|FD-Score:4.27|P-value:2.55E-4 ID:SGTC_2938|Compound:9059746|FD-Score:6.60|P-value:3.36E-8 ID:SGTC_2948|Compound:9070189|FD-Score:9.79|P-value:4.97E-16 ID:SGTC_2974|Compound:9094440|FD-Score:5.05|P-value:1.92E-5 ID:SGTC_2976|Compound:9009005|FD-Score:-4.30|P-value:1.68E-4 ID:SGTC_2981|Compound:9013952|FD-Score:5.50|P-value:3.54E-6 ID:SGTC_2993|Compound:9054257|FD-Score:20.30|P-value:6.33E-63 ID:SGTC_3018|Compound:9082602|FD-Score:3.81|P-value:9.71E-4 ID:SGTC_3033|Compound:9090887|FD-Score:5.24|P-value:9.52E-6 ID:SGTC_3071|Compound:9117417|FD-Score:3.96|P-value:6.40E-4 ID:SGTC_3081|Compound:9117243|FD-Score:6.19|P-value:2.10E-7 ID:SGTC_3126|Compound:9127922|FD-Score:10.10|P-value:6.27E-17 ID:SGTC_3152|Compound:9099253|FD-Score:5.71|P-value:1.54E-6 ID:SGTC_3195|Compound:9113082|FD-Score:-4.99|P-value:1.62E-5 ID:SGTC_3218|Compound:9131285|FD-Score:4.29|P-value:2.35E-4 ID:SGTC_3308|Compound:9128332|FD-Score:6.16|P-value:2.42E-7 ID:SGTC_3347|Compound:9188721|FD-Score:5.96|P-value:5.46E-7

Top fitness defect scores for YER031C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2993 9054257 20.30 71.4 µM 6.33E-63 fatty acid desaturase (OLE1) 4 4.92E-92
2 SGTC_788 1182-0090 19.80 188.0 µM 1.16E-59 endomembrane recycling 3 3.18E-87
3 SGTC_2006 4011487 18.70 200.0 µM 8.93E-54 endomembrane recycling 5 1.50E-78
4 SGTC_768 0384-0033 18.50 77.3 µM 2.57E-52 fatty acid desaturase (OLE1) 5 2.13E-76
5 SGTC_1005 4092-0690 15.70 4.4 µM 1.37E-38 plasma membrane duress 2 3.60E-56
6 SGTC_1781 st038725 14.10 66.3 µM 3.84E-31 NEO1 7 3.42E-45
7 SGTC_1797 st048695 12.40 56.8 µM 1.38E-24 NEO1 11 1.55E-35
8 SGTC_278 4092-0821 11.20 23.9 µM 2.27E-20 plasma membrane duress 4 2.54E-29
9 SGTC_875 0709-0210 11.20 25.7 µM 2.31E-20 fatty acid desaturase (OLE1) 4 2.61E-29
10 SGTC_2725 haloperidol 10.40 53.2 µM 6.62E-18 plasma membrane duress 11 1.08E-25
11 SGTC_3126 9127922 10.10 49.5 µM 6.27E-17 fatty acid desaturase (OLE1) 6 2.97E-24
12 SGTC_1019 4262-0212 9.80 3.4 µM 4.66E-16 ergosterol depletion effects on membrane 6 5.71E-23
13 SGTC_2948 9070189 9.79 9.4 µM 4.97E-16 plasma membrane duress 13 6.27E-23
14 SGTC_868 0527-0199 9.77 213.0 µM 5.84E-16 fatty acid desaturase (OLE1) 3 7.95E-23
15 SGTC_1081 sertraline 9.65 6.0 µM 1.23E-15 60S ribosome export 3 2.38E-22
16 SGTC_954 1189-0853 9.65 2.9 µM 1.26E-15 endomembrane recycling 3 2.48E-22
17 SGTC_1072 oxiconazole 9.46 14.9 nM 4.30E-15 ergosterol depletion effects on membrane 8 1.50E-21
18 SGTC_312 4092-0653 9.40 6.8 µM 6.25E-15 ergosterol depletion effects on membrane 14 2.61E-21
19 SGTC_459 nigericin 9.16 15.3 µM 2.99E-14 7 2.61E-20
20 SGTC_2038 4100038 9.06 31.0 µM 5.64E-14 plasma membrane duress 14 6.64E-20

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.607 0 YJL204C RCY1 hom F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth
0.581 7.26E-302 YDL226C GCS1 hom ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
0.546 5.79E-259 YJL207C LAA1 hom AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene
0.509 1.58E-220 YCR094W CDC50 hom Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication
0.504 2.55E-215 YFL034W_p YFL034W_p hom Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk
0.467 3.46E-181 YMR071C TVP18 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments
0.456 1.30E-171 YKL135C APL2 hom Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress
0.400 9.59E-129 YOR070C GYP1 hom Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
0.376 2.73E-112 YDL090C RAM1 hom Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit
0.373 8.53E-111 YOR039W CKB2 hom Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase
0.365 1.15E-105 YNL267W PIK1 het Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton
0.355 1.79E-100 YGL199C_d YGL199C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YIP4/YGL198W
0.355 2.96E-100 YGL019W CKB1 hom Beta regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
0.353 6.93E-99 YHL019C APM2 hom Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport
0.336 4.67E-89 YOR115C TRS33 hom One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic