Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.118 |
7.88E-12 |
YBR131W |
CCZ1 |
hom |
Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway |
0.112 |
7.58E-11 |
YDR371W_p |
CTS2_p |
hom |
Putative chitinase, functionally complements A. gossypii cts2 mutant sporulation defect |
0.108 |
2.93E-10 |
YCR012W |
PGK1 |
het |
3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis |
0.104 |
1.74E-9 |
YLR099C |
ICT1 |
hom |
Lysophosphatidic acid acyltransferase; responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress; ICT1 has a paralog, ECM18, that arose from the whole genome duplication |
0.103 |
1.86E-9 |
YKR031C |
SPO14 |
hom |
Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with foot domain of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions |
0.099 |
9.44E-9 |
YDR018C_p |
YDR018C_p |
hom |
Probable membrane protein with three predicted transmembrane domains; similar to C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate acyltransferase; YDR018C has a paralog, CST26, that arose from the whole genome duplication |
0.099 |
9.67E-9 |
YOR284W |
HUA2 |
hom |
Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly |
0.096 |
2.43E-8 |
YKR002W |
PAP1 |
het |
Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping |
0.095 |
3.11E-8 |
YGR091W |
PRP31 |
het |
Splicing factor, component of the U4/U6-U5 snRNP complex |
0.092 |
1.06E-7 |
YGR073C_d |
YGR073C_d |
het |
Dubious open reading frame unlikely to encode a functional protein, extensively overlaps essential SMD1 gene encoding a U6 snRNP protein |
0.089 |
2.56E-7 |
YLR078C |
BOS1 |
het |
v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi |
0.088 |
3.37E-7 |
YMR188C |
MRPS17 |
hom |
Mitochondrial ribosomal protein of the small subunit |
0.088 |
3.81E-7 |
YMR133W |
REC114 |
hom |
Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division |
0.085 |
7.54E-7 |
YJL212C |
OPT1 |
hom |
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family |
0.085 |
8.22E-7 |
YNL046W_p |
YNL046W_p |
hom |
Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) |