YGL093W / SPC105

Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components

Zygosity: Heterozygous strain
fixedexpanded
Profile for YGL093W / SPC105

Click on Significant Values for Screen Details ID:SGTC_16|Compound:erodoxin|FD-Score:4.54|P-value:2.14E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:4.28|P-value:4.43E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:4.20|P-value:5.46E-4 ID:SGTC_64|Compound:000l-0018|FD-Score:14.50|P-value:1.12E-29 ID:SGTC_67|Compound:0335-0847|FD-Score:6.59|P-value:1.57E-7 ID:SGTC_86|Compound:0417-1630|FD-Score:10.80|P-value:3.51E-17 ID:SGTC_103|Compound:0844-0104|FD-Score:6.08|P-value:1.17E-6 ID:SGTC_107|Compound:0358-0022|FD-Score:15.30|P-value:6.44E-33 ID:SGTC_137|Compound:0438-0332|FD-Score:10.90|P-value:1.80E-17 ID:SGTC_138|Compound:0850-0259|FD-Score:7.99|P-value:2.78E-10 ID:SGTC_142|Compound:0335-0849|FD-Score:15.00|P-value:1.15E-31 ID:SGTC_157|Compound:1348-1695|FD-Score:9.79|P-value:1.52E-14 ID:SGTC_158|Compound:k038-0087|FD-Score:11.90|P-value:1.80E-20 ID:SGTC_163|Compound:1327-0036|FD-Score:7.35|P-value:5.80E-9 ID:SGTC_165|Compound:k038-0023|FD-Score:6.26|P-value:5.82E-7 ID:SGTC_168|Compound:3970-0862|FD-Score:5.24|P-value:2.38E-5 ID:SGTC_177|Compound:1327-0068|FD-Score:5.20|P-value:2.70E-5 ID:SGTC_200|Compound:k038-0079|FD-Score:12.90|P-value:7.02E-24 ID:SGTC_207|Compound:4185-0010|FD-Score:-4.03|P-value:9.21E-4 ID:SGTC_214|Compound:4373-3496|FD-Score:4.99|P-value:5.36E-5 ID:SGTC_216|Compound:k038-0035|FD-Score:12.00|P-value:8.43E-21 ID:SGTC_248|Compound:streptozotocin|FD-Score:4.30|P-value:4.14E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:10.20|P-value:1.37E-15 ID:SGTC_294|Compound:k038-0071|FD-Score:16.00|P-value:1.15E-35 ID:SGTC_295|Compound:k015-0027|FD-Score:4.18|P-value:5.81E-4 ID:SGTC_312|Compound:4092-0653|FD-Score:-4.80|P-value:1.03E-4 ID:SGTC_332|Compound:4112-0506|FD-Score:6.76|P-value:7.76E-8 ID:SGTC_340|Compound:k038-0059|FD-Score:7.79|P-value:7.52E-10 ID:SGTC_351|Compound:caspofungin|FD-Score:6.02|P-value:1.47E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:5.54|P-value:8.56E-6 ID:SGTC_388|Compound:3',4'-dichloroisocoumarin|FD-Score:8.82|P-value:3.84E-12 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.19|P-value:5.69E-4 ID:SGTC_520|Compound:3584-0023|FD-Score:7.78|P-value:7.85E-10 ID:SGTC_525|Compound:k781-2675|FD-Score:4.33|P-value:3.90E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:7.64|P-value:1.50E-9 ID:SGTC_580|Compound:1123-0028|FD-Score:6.36|P-value:3.95E-7 ID:SGTC_586|Compound:0957-0265|FD-Score:5.81|P-value:3.19E-6 ID:SGTC_635|Compound:k038-0028|FD-Score:15.40|P-value:2.98E-33 ID:SGTC_673|Compound:1082-0474|FD-Score:9.64|P-value:3.77E-14 ID:SGTC_676|Compound:falcarinol|FD-Score:4.02|P-value:8.98E-4 ID:SGTC_709|Compound:3807-1509|FD-Score:5.96|P-value:1.88E-6 ID:SGTC_720|Compound:r052-1644|FD-Score:4.58|P-value:1.89E-4 ID:SGTC_743|Compound:1275-0778|FD-Score:6.19|P-value:7.63E-7 ID:SGTC_759|Compound:3486-0358|FD-Score:7.09|P-value:1.88E-8 ID:SGTC_794|Compound:k038-0031|FD-Score:8.56|P-value:1.58E-11 ID:SGTC_829|Compound:1635-0120|FD-Score:8.89|P-value:2.66E-12 ID:SGTC_846|Compound:0335-0850|FD-Score:4.69|P-value:1.37E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:4.05|P-value:8.34E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:8.09|P-value:1.76E-10 ID:SGTC_885|Compound:0865-0106|FD-Score:6.21|P-value:7.30E-7 ID:SGTC_928|Compound:2764-0428|FD-Score:3.98|P-value:9.86E-4 ID:SGTC_946|Compound:3434-1334|FD-Score:4.70|P-value:1.30E-4 ID:SGTC_958|Compound:1222-0007|FD-Score:-4.53|P-value:2.26E-4 ID:SGTC_966|Compound:1300-0360|FD-Score:4.95|P-value:6.03E-5 ID:SGTC_984|Compound:1492-0255|FD-Score:11.00|P-value:7.34E-18 ID:SGTC_1038|Compound:k292-0204|FD-Score:7.49|P-value:3.03E-9 ID:SGTC_1044|Compound:1222-0021|FD-Score:5.06|P-value:4.26E-5 ID:SGTC_1057|Compound:3448-5381|FD-Score:5.03|P-value:4.63E-5 ID:SGTC_1074|Compound:carmofur|FD-Score:5.98|P-value:1.76E-6 ID:SGTC_1082|Compound:camptothecin|FD-Score:4.51|P-value:2.29E-4 ID:SGTC_1098|Compound:clofazimine|FD-Score:4.85|P-value:8.37E-5 ID:SGTC_1113|Compound:artemisinin|FD-Score:5.85|P-value:2.82E-6 ID:SGTC_1133|Compound:3473-0247|FD-Score:8.86|P-value:3.15E-12 ID:SGTC_1161|Compound:k007-0610|FD-Score:6.32|P-value:4.60E-7 ID:SGTC_1239|Compound:0337-0584|FD-Score:15.50|P-value:1.83E-33 ID:SGTC_1255|Compound:0566-0045|FD-Score:5.53|P-value:8.81E-6 ID:SGTC_1294|Compound:1000-1494|FD-Score:18.80|P-value:1.76E-48 ID:SGTC_1319|Compound:1306-0155|FD-Score:9.84|P-value:1.16E-14 ID:SGTC_1374|Compound:2889-5571|FD-Score:12.40|P-value:2.55E-22 ID:SGTC_1396|Compound:3511-0007|FD-Score:5.65|P-value:5.86E-6 ID:SGTC_1450|Compound:4112-4260|FD-Score:-5.43|P-value:1.34E-5 ID:SGTC_1481|Compound:3346-2004|FD-Score:4.31|P-value:4.13E-4 ID:SGTC_1493|Compound:4348-0038|FD-Score:9.77|P-value:1.74E-14 ID:SGTC_1522|Compound:st012842|FD-Score:-4.10|P-value:7.60E-4 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:4.13|P-value:6.65E-4 ID:SGTC_1615|Compound:st002656|FD-Score:4.68|P-value:1.41E-4 ID:SGTC_1622|Compound:st003707|FD-Score:5.45|P-value:1.18E-5 ID:SGTC_1624|Compound:st003710|FD-Score:4.80|P-value:9.59E-5 ID:SGTC_1652|Compound:st011932|FD-Score:14.70|P-value:3.03E-30 ID:SGTC_1656|Compound:st012921|FD-Score:4.52|P-value:2.24E-4 ID:SGTC_1672|Compound:st016598|FD-Score:5.08|P-value:3.95E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:12.00|P-value:8.50E-21 ID:SGTC_1707|Compound:st032323|FD-Score:5.03|P-value:4.77E-5 ID:SGTC_1750|Compound:st081859|FD-Score:10.40|P-value:3.64E-16 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:7.66|P-value:1.37E-9 ID:SGTC_1797|Compound:st048695|FD-Score:4.68|P-value:1.38E-4 ID:SGTC_1884|Compound:5633444|FD-Score:4.37|P-value:3.42E-4 ID:SGTC_1894|Compound:3',6'-dihydroxyflavone|FD-Score:4.42|P-value:3.03E-4 ID:SGTC_1897|Compound:st060201|FD-Score:4.61|P-value:1.72E-4 ID:SGTC_1898|Compound:st060199|FD-Score:4.16|P-value:6.14E-4 ID:SGTC_1900|Compound:st060200|FD-Score:-4.14|P-value:6.87E-4 ID:SGTC_1901|Compound:st060216|FD-Score:-4.09|P-value:7.77E-4 ID:SGTC_1915|Compound:st067105|FD-Score:6.10|P-value:1.11E-6 ID:SGTC_1952|Compound:st077036|FD-Score:4.77|P-value:1.08E-4 ID:SGTC_1962|Compound:st076595|FD-Score:5.61|P-value:6.58E-6 ID:SGTC_1968|Compound:st069590|FD-Score:16.80|P-value:4.22E-39 ID:SGTC_2006|Compound:4011487|FD-Score:4.28|P-value:4.49E-4 ID:SGTC_2041|Compound:5107442|FD-Score:6.77|P-value:7.50E-8 ID:SGTC_2066|Compound:5222451|FD-Score:4.94|P-value:6.28E-5 ID:SGTC_2109|Compound:5483026|FD-Score:9.31|P-value:2.60E-13 ID:SGTC_2111|Compound:5486399|FD-Score:12.80|P-value:1.91E-23 ID:SGTC_2124|Compound:5246320|FD-Score:5.22|P-value:2.55E-5 ID:SGTC_2140|Compound:5586273|FD-Score:6.63|P-value:1.32E-7 ID:SGTC_2163|Compound:5671233|FD-Score:6.41|P-value:3.30E-7 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:5.20|P-value:2.72E-5 ID:SGTC_2180|Compound:6301957|FD-Score:4.38|P-value:3.31E-4 ID:SGTC_2186|Compound:6124449|FD-Score:9.03|P-value:1.25E-12 ID:SGTC_2187|Compound:6125751|FD-Score:5.06|P-value:4.30E-5 ID:SGTC_2188|Compound:6126565|FD-Score:4.50|P-value:2.37E-4 ID:SGTC_2233|Compound:sulbentine|FD-Score:5.18|P-value:2.88E-5 ID:SGTC_2249|Compound:haloperidol|FD-Score:-4.13|P-value:7.05E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-4.03|P-value:9.15E-4 ID:SGTC_2289|Compound:7946404|FD-Score:4.35|P-value:3.62E-4 ID:SGTC_2301|Compound:7769476|FD-Score:4.59|P-value:1.85E-4 ID:SGTC_2344|Compound:7990960|FD-Score:4.10|P-value:7.34E-4 ID:SGTC_2348|Compound:9022543|FD-Score:6.09|P-value:1.16E-6 ID:SGTC_2370|Compound:9071495|FD-Score:8.61|P-value:1.19E-11 ID:SGTC_2378|Compound:9074213|FD-Score:5.69|P-value:4.95E-6 ID:SGTC_2396|Compound:5342950|FD-Score:10.80|P-value:2.54E-17 ID:SGTC_2400|Compound:5203494|FD-Score:4.39|P-value:3.26E-4 ID:SGTC_2429|Compound:5902844|FD-Score:19.00|P-value:2.20E-49 ID:SGTC_2485|Compound:5633444|FD-Score:5.94|P-value:2.04E-6 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:5.25|P-value:2.27E-5 ID:SGTC_2534|Compound:helenine|FD-Score:7.87|P-value:5.12E-10 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:6.32|P-value:4.58E-7 ID:SGTC_2544|Compound:sphondin|FD-Score:5.76|P-value:3.89E-6 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:4.34|P-value:3.78E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:4.50|P-value:2.36E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:10.70|P-value:6.40E-17 ID:SGTC_2890|Compound:9046729|FD-Score:7.97|P-value:3.18E-10 ID:SGTC_2912|Compound:7964298|FD-Score:14.10|P-value:2.65E-28 ID:SGTC_2930|Compound:9013230|FD-Score:4.24|P-value:5.01E-4 ID:SGTC_2980|Compound:9014342|FD-Score:4.56|P-value:2.01E-4 ID:SGTC_2997|Compound:9067075|FD-Score:8.62|P-value:1.10E-11 ID:SGTC_3022|Compound:9087993|FD-Score:4.26|P-value:4.69E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:26.40|P-value:3.73E-93 ID:SGTC_3060|Compound:1327-0027|FD-Score:19.80|P-value:1.26E-53 ID:SGTC_3063|Compound:1327-0034|FD-Score:21.10|P-value:2.88E-60 ID:SGTC_3064|Compound:1327-0027|FD-Score:12.40|P-value:2.37E-22 ID:SGTC_3076|Compound:9116187|FD-Score:6.23|P-value:6.76E-7 ID:SGTC_3148|Compound:9097893|FD-Score:4.25|P-value:4.80E-4 ID:SGTC_3247|Compound:9135149|FD-Score:4.01|P-value:9.27E-4 ID:SGTC_3277|Compound:9138724|FD-Score:4.48|P-value:2.49E-4 ID:SGTC_3278|Compound:9139605|FD-Score:5.17|P-value:2.96E-5 ID:SGTC_3318|Compound:9139014|FD-Score:4.60|P-value:1.79E-4 ID:SGTC_16|Compound:erodoxin|FD-Score:4.54|P-value:2.14E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:4.28|P-value:4.43E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:4.20|P-value:5.46E-4 ID:SGTC_64|Compound:000l-0018|FD-Score:14.50|P-value:1.12E-29 ID:SGTC_67|Compound:0335-0847|FD-Score:6.59|P-value:1.57E-7 ID:SGTC_86|Compound:0417-1630|FD-Score:10.80|P-value:3.51E-17 ID:SGTC_103|Compound:0844-0104|FD-Score:6.08|P-value:1.17E-6 ID:SGTC_107|Compound:0358-0022|FD-Score:15.30|P-value:6.44E-33 ID:SGTC_137|Compound:0438-0332|FD-Score:10.90|P-value:1.80E-17 ID:SGTC_138|Compound:0850-0259|FD-Score:7.99|P-value:2.78E-10 ID:SGTC_142|Compound:0335-0849|FD-Score:15.00|P-value:1.15E-31 ID:SGTC_157|Compound:1348-1695|FD-Score:9.79|P-value:1.52E-14 ID:SGTC_158|Compound:k038-0087|FD-Score:11.90|P-value:1.80E-20 ID:SGTC_163|Compound:1327-0036|FD-Score:7.35|P-value:5.80E-9 ID:SGTC_165|Compound:k038-0023|FD-Score:6.26|P-value:5.82E-7 ID:SGTC_168|Compound:3970-0862|FD-Score:5.24|P-value:2.38E-5 ID:SGTC_177|Compound:1327-0068|FD-Score:5.20|P-value:2.70E-5 ID:SGTC_200|Compound:k038-0079|FD-Score:12.90|P-value:7.02E-24 ID:SGTC_207|Compound:4185-0010|FD-Score:-4.03|P-value:9.21E-4 ID:SGTC_214|Compound:4373-3496|FD-Score:4.99|P-value:5.36E-5 ID:SGTC_216|Compound:k038-0035|FD-Score:12.00|P-value:8.43E-21 ID:SGTC_248|Compound:streptozotocin|FD-Score:4.30|P-value:4.14E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:10.20|P-value:1.37E-15 ID:SGTC_294|Compound:k038-0071|FD-Score:16.00|P-value:1.15E-35 ID:SGTC_295|Compound:k015-0027|FD-Score:4.18|P-value:5.81E-4 ID:SGTC_312|Compound:4092-0653|FD-Score:-4.80|P-value:1.03E-4 ID:SGTC_332|Compound:4112-0506|FD-Score:6.76|P-value:7.76E-8 ID:SGTC_340|Compound:k038-0059|FD-Score:7.79|P-value:7.52E-10 ID:SGTC_351|Compound:caspofungin|FD-Score:6.02|P-value:1.47E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:5.54|P-value:8.56E-6 ID:SGTC_388|Compound:3',4'-dichloroisocoumarin|FD-Score:8.82|P-value:3.84E-12 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.19|P-value:5.69E-4 ID:SGTC_520|Compound:3584-0023|FD-Score:7.78|P-value:7.85E-10 ID:SGTC_525|Compound:k781-2675|FD-Score:4.33|P-value:3.90E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:7.64|P-value:1.50E-9 ID:SGTC_580|Compound:1123-0028|FD-Score:6.36|P-value:3.95E-7 ID:SGTC_586|Compound:0957-0265|FD-Score:5.81|P-value:3.19E-6 ID:SGTC_635|Compound:k038-0028|FD-Score:15.40|P-value:2.98E-33 ID:SGTC_673|Compound:1082-0474|FD-Score:9.64|P-value:3.77E-14 ID:SGTC_676|Compound:falcarinol|FD-Score:4.02|P-value:8.98E-4 ID:SGTC_709|Compound:3807-1509|FD-Score:5.96|P-value:1.88E-6 ID:SGTC_720|Compound:r052-1644|FD-Score:4.58|P-value:1.89E-4 ID:SGTC_743|Compound:1275-0778|FD-Score:6.19|P-value:7.63E-7 ID:SGTC_759|Compound:3486-0358|FD-Score:7.09|P-value:1.88E-8 ID:SGTC_794|Compound:k038-0031|FD-Score:8.56|P-value:1.58E-11 ID:SGTC_829|Compound:1635-0120|FD-Score:8.89|P-value:2.66E-12 ID:SGTC_846|Compound:0335-0850|FD-Score:4.69|P-value:1.37E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:4.05|P-value:8.34E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:8.09|P-value:1.76E-10 ID:SGTC_885|Compound:0865-0106|FD-Score:6.21|P-value:7.30E-7 ID:SGTC_928|Compound:2764-0428|FD-Score:3.98|P-value:9.86E-4 ID:SGTC_946|Compound:3434-1334|FD-Score:4.70|P-value:1.30E-4 ID:SGTC_958|Compound:1222-0007|FD-Score:-4.53|P-value:2.26E-4 ID:SGTC_966|Compound:1300-0360|FD-Score:4.95|P-value:6.03E-5 ID:SGTC_984|Compound:1492-0255|FD-Score:11.00|P-value:7.34E-18 ID:SGTC_1038|Compound:k292-0204|FD-Score:7.49|P-value:3.03E-9 ID:SGTC_1044|Compound:1222-0021|FD-Score:5.06|P-value:4.26E-5 ID:SGTC_1057|Compound:3448-5381|FD-Score:5.03|P-value:4.63E-5 ID:SGTC_1074|Compound:carmofur|FD-Score:5.98|P-value:1.76E-6 ID:SGTC_1082|Compound:camptothecin|FD-Score:4.51|P-value:2.29E-4 ID:SGTC_1098|Compound:clofazimine|FD-Score:4.85|P-value:8.37E-5 ID:SGTC_1113|Compound:artemisinin|FD-Score:5.85|P-value:2.82E-6 ID:SGTC_1133|Compound:3473-0247|FD-Score:8.86|P-value:3.15E-12 ID:SGTC_1161|Compound:k007-0610|FD-Score:6.32|P-value:4.60E-7 ID:SGTC_1239|Compound:0337-0584|FD-Score:15.50|P-value:1.83E-33 ID:SGTC_1255|Compound:0566-0045|FD-Score:5.53|P-value:8.81E-6 ID:SGTC_1294|Compound:1000-1494|FD-Score:18.80|P-value:1.76E-48 ID:SGTC_1319|Compound:1306-0155|FD-Score:9.84|P-value:1.16E-14 ID:SGTC_1374|Compound:2889-5571|FD-Score:12.40|P-value:2.55E-22 ID:SGTC_1396|Compound:3511-0007|FD-Score:5.65|P-value:5.86E-6 ID:SGTC_1450|Compound:4112-4260|FD-Score:-5.43|P-value:1.34E-5 ID:SGTC_1481|Compound:3346-2004|FD-Score:4.31|P-value:4.13E-4 ID:SGTC_1493|Compound:4348-0038|FD-Score:9.77|P-value:1.74E-14 ID:SGTC_1522|Compound:st012842|FD-Score:-4.10|P-value:7.60E-4 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:4.13|P-value:6.65E-4 ID:SGTC_1615|Compound:st002656|FD-Score:4.68|P-value:1.41E-4 ID:SGTC_1622|Compound:st003707|FD-Score:5.45|P-value:1.18E-5 ID:SGTC_1624|Compound:st003710|FD-Score:4.80|P-value:9.59E-5 ID:SGTC_1652|Compound:st011932|FD-Score:14.70|P-value:3.03E-30 ID:SGTC_1656|Compound:st012921|FD-Score:4.52|P-value:2.24E-4 ID:SGTC_1672|Compound:st016598|FD-Score:5.08|P-value:3.95E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:12.00|P-value:8.50E-21 ID:SGTC_1707|Compound:st032323|FD-Score:5.03|P-value:4.77E-5 ID:SGTC_1750|Compound:st081859|FD-Score:10.40|P-value:3.64E-16 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:7.66|P-value:1.37E-9 ID:SGTC_1797|Compound:st048695|FD-Score:4.68|P-value:1.38E-4 ID:SGTC_1884|Compound:5633444|FD-Score:4.37|P-value:3.42E-4 ID:SGTC_1894|Compound:3',6'-dihydroxyflavone|FD-Score:4.42|P-value:3.03E-4 ID:SGTC_1897|Compound:st060201|FD-Score:4.61|P-value:1.72E-4 ID:SGTC_1898|Compound:st060199|FD-Score:4.16|P-value:6.14E-4 ID:SGTC_1900|Compound:st060200|FD-Score:-4.14|P-value:6.87E-4 ID:SGTC_1901|Compound:st060216|FD-Score:-4.09|P-value:7.77E-4 ID:SGTC_1915|Compound:st067105|FD-Score:6.10|P-value:1.11E-6 ID:SGTC_1952|Compound:st077036|FD-Score:4.77|P-value:1.08E-4 ID:SGTC_1962|Compound:st076595|FD-Score:5.61|P-value:6.58E-6 ID:SGTC_1968|Compound:st069590|FD-Score:16.80|P-value:4.22E-39 ID:SGTC_2006|Compound:4011487|FD-Score:4.28|P-value:4.49E-4 ID:SGTC_2041|Compound:5107442|FD-Score:6.77|P-value:7.50E-8 ID:SGTC_2066|Compound:5222451|FD-Score:4.94|P-value:6.28E-5 ID:SGTC_2109|Compound:5483026|FD-Score:9.31|P-value:2.60E-13 ID:SGTC_2111|Compound:5486399|FD-Score:12.80|P-value:1.91E-23 ID:SGTC_2124|Compound:5246320|FD-Score:5.22|P-value:2.55E-5 ID:SGTC_2140|Compound:5586273|FD-Score:6.63|P-value:1.32E-7 ID:SGTC_2163|Compound:5671233|FD-Score:6.41|P-value:3.30E-7 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:5.20|P-value:2.72E-5 ID:SGTC_2180|Compound:6301957|FD-Score:4.38|P-value:3.31E-4 ID:SGTC_2186|Compound:6124449|FD-Score:9.03|P-value:1.25E-12 ID:SGTC_2187|Compound:6125751|FD-Score:5.06|P-value:4.30E-5 ID:SGTC_2188|Compound:6126565|FD-Score:4.50|P-value:2.37E-4 ID:SGTC_2233|Compound:sulbentine|FD-Score:5.18|P-value:2.88E-5 ID:SGTC_2249|Compound:haloperidol|FD-Score:-4.13|P-value:7.05E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-4.03|P-value:9.15E-4 ID:SGTC_2289|Compound:7946404|FD-Score:4.35|P-value:3.62E-4 ID:SGTC_2301|Compound:7769476|FD-Score:4.59|P-value:1.85E-4 ID:SGTC_2344|Compound:7990960|FD-Score:4.10|P-value:7.34E-4 ID:SGTC_2348|Compound:9022543|FD-Score:6.09|P-value:1.16E-6 ID:SGTC_2370|Compound:9071495|FD-Score:8.61|P-value:1.19E-11 ID:SGTC_2378|Compound:9074213|FD-Score:5.69|P-value:4.95E-6 ID:SGTC_2396|Compound:5342950|FD-Score:10.80|P-value:2.54E-17 ID:SGTC_2400|Compound:5203494|FD-Score:4.39|P-value:3.26E-4 ID:SGTC_2429|Compound:5902844|FD-Score:19.00|P-value:2.20E-49 ID:SGTC_2485|Compound:5633444|FD-Score:5.94|P-value:2.04E-6 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:5.25|P-value:2.27E-5 ID:SGTC_2534|Compound:helenine|FD-Score:7.87|P-value:5.12E-10 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:6.32|P-value:4.58E-7 ID:SGTC_2544|Compound:sphondin|FD-Score:5.76|P-value:3.89E-6 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:4.34|P-value:3.78E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:4.50|P-value:2.36E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:10.70|P-value:6.40E-17 ID:SGTC_2890|Compound:9046729|FD-Score:7.97|P-value:3.18E-10 ID:SGTC_2912|Compound:7964298|FD-Score:14.10|P-value:2.65E-28 ID:SGTC_2930|Compound:9013230|FD-Score:4.24|P-value:5.01E-4 ID:SGTC_2980|Compound:9014342|FD-Score:4.56|P-value:2.01E-4 ID:SGTC_2997|Compound:9067075|FD-Score:8.62|P-value:1.10E-11 ID:SGTC_3022|Compound:9087993|FD-Score:4.26|P-value:4.69E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:26.40|P-value:3.73E-93 ID:SGTC_3060|Compound:1327-0027|FD-Score:19.80|P-value:1.26E-53 ID:SGTC_3063|Compound:1327-0034|FD-Score:21.10|P-value:2.88E-60 ID:SGTC_3064|Compound:1327-0027|FD-Score:12.40|P-value:2.37E-22 ID:SGTC_3076|Compound:9116187|FD-Score:6.23|P-value:6.76E-7 ID:SGTC_3148|Compound:9097893|FD-Score:4.25|P-value:4.80E-4 ID:SGTC_3247|Compound:9135149|FD-Score:4.01|P-value:9.27E-4 ID:SGTC_3277|Compound:9138724|FD-Score:4.48|P-value:2.49E-4 ID:SGTC_3278|Compound:9139605|FD-Score:5.17|P-value:2.96E-5 ID:SGTC_3318|Compound:9139014|FD-Score:4.60|P-value:1.79E-4

Top fitness defect scores for YGL093W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_3059 1327-0034 26.40 3.0 µM 3.73E-93 2 1.91E-153 19.70
2 SGTC_3063 1327-0034 21.10 4.0 µM 2.88E-60 2 8.68E-99 15.10
3 SGTC_3060 1327-0027 19.80 12.5 µM 1.26E-53 2 9.37E-88 13.40
4 SGTC_2429 5902844 19.00 64.4 µM 2.20E-49 2 1.03E-80 13.30
5 SGTC_1294 1000-1494 18.80 117.0 µM 1.76E-48 2 3.26E-79 6.31
6 SGTC_1968 st069590 16.80 43.6 µM 4.22E-39 2 1.22E-63 4.18
7 SGTC_294 k038-0071 16.00 157.0 µM 1.15E-35 ubiquinone biosynthesis & proteasome 1 6.16E-58 5.29
8 SGTC_1239 0337-0584 15.50 35.4 µM 1.83E-33 unfolded protein response 2 2.78E-54 0.15
9 SGTC_635 k038-0028 15.40 24.7 µM 2.98E-33 ubiquinone biosynthesis & proteasome 1 6.23E-54 4.84
10 SGTC_107 0358-0022 15.30 2.7 µM 6.44E-33 SWF1 & branched chain AA biosynthesis 1 2.23E-53 7.73
11 SGTC_142 0335-0849 15.00 62.7 µM 1.15E-31 ubiquinone biosynthesis & proteasome 3 2.68E-51 1.45
12 SGTC_1652 st011932 14.70 78.0 µM 3.03E-30 RSC complex & mRNA processing 6 6.04E-49 0.70
13 SGTC_64 000l-0018 14.50 272.1 µM 1.12E-29 ubiquinone biosynthesis & proteasome 8 5.28E-48 2.27
14 SGTC_2912 7964298 14.10 10.9 µM 2.65E-28 cell wall 4 1.01E-45 0.02
15 SGTC_200 k038-0079 12.90 37.5 µM 7.02E-24 ubiquinone biosynthesis & proteasome 2 2.15E-38 5.45
16 SGTC_2111 5486399 12.80 200.0 µM 1.91E-23 5 1.13E-37 0.82
17 SGTC_3064 1327-0027 12.40 10.0 µM 2.37E-22 2 7.36E-36 7.29
18 SGTC_1374 2889-5571 12.40 141.0 µM 2.55E-22 RSC complex & mRNA processing 7 8.29E-36 0.10
19 SGTC_216 k038-0035 12.00 28.4 µM 8.43E-21 ubiquinone biosynthesis & proteasome 2 2.72E-33 2.69
20 SGTC_1679 4130-1276 12.00 6.7 µM 8.50E-21 Golgi 2 2.76E-33 0.05

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.766 0 YPR107C YTH1 het Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation
0.484 3.89E-196 YFR007W YFH7 hom Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases
0.453 2.62E-169 YDL183C YDL183C hom Mitochondrial inner-membrane protein thought to be involved in the formation of an active mitochondrial K+/H+ exchanger (KHE) system; non-essential gene
0.451 1.78E-167 YER041W YEN1 hom Holliday junction resolvase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1 and has similarity to S. cerevisiae endonuclease Rth1p
0.442 9.14E-161 YPR146C_d YPR146C_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.420 2.70E-143 YDR537C_d YDR537C_d hom Dubious open reading frame unlikely to encode a protein, almost completely overlaps verified ORF PAD1/YDR538W
0.405 3.06E-132 YCL014W BUD3 hom Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
0.404 6.74E-132 YJL155C FBP26 hom Fructose-2,6-bisphosphatase, required for glucose metabolism; protein abundance increases in response to DNA replication stress
0.388 6.50E-121 YNR016C ACC1 het Acetyl-CoA carboxylase, biotin containing enzyme; catalyzes the carboxylation of cytosolic acetyl-CoA to form malonyl-CoA and regulates histone acetylation by regulating the availablity of acetyl-CoA; required for de novo biosynthesis of long-chain fatty acids;
0.386 1.46E-119 YLR033W RSC58 het Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance
0.382 2.91E-117 YJR129C_p YJR129C_p hom Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
0.367 1.66E-107 YJL193W_p YJL193W_p hom Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect
0.365 3.68E-106 YER165W PAB1 het Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
0.353 2.67E-99 YFR037C RSC8 het Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
0.342 1.04E-92 YML034W SRC1 hom Inner nuclear membrane protein; functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has aneuploidy tolerance