YGL099W / LSG1

Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm

Zygosity: Heterozygous strain
fixedexpanded
Profile for YGL099W / LSG1

Click on Significant Values for Screen Details ID:SGTC_49|Compound:0717-0965|FD-Score:15.90|P-value:6.65E-37 ID:SGTC_57|Compound:miconazole|FD-Score:-5.18|P-value:1.63E-5 ID:SGTC_62|Compound:0180-0423|FD-Score:14.10|P-value:2.27E-29 ID:SGTC_85|Compound:0868-0259|FD-Score:9.57|P-value:1.80E-14 ID:SGTC_97|Compound:0535-0701|FD-Score:23.90|P-value:1.65E-80 ID:SGTC_100|Compound:0086-0128|FD-Score:4.29|P-value:3.67E-4 ID:SGTC_115|Compound:0527-0192|FD-Score:4.55|P-value:1.66E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:11.90|P-value:2.11E-21 ID:SGTC_121|Compound:0557-0495|FD-Score:11.00|P-value:1.15E-18 ID:SGTC_135|Compound:0933-0004|FD-Score:15.70|P-value:5.63E-36 ID:SGTC_136|Compound:0097-0015|FD-Score:8.79|P-value:1.74E-12 ID:SGTC_160|Compound:3453-0671|FD-Score:8.09|P-value:7.83E-11 ID:SGTC_167|Compound:3672-0051|FD-Score:4.59|P-value:1.50E-4 ID:SGTC_171|Compound:k064-0041|FD-Score:12.80|P-value:1.57E-24 ID:SGTC_183|Compound:3914-0051|FD-Score:12.00|P-value:7.24E-22 ID:SGTC_191|Compound:3914-0123|FD-Score:6.76|P-value:4.52E-8 ID:SGTC_198|Compound:3454-2873|FD-Score:9.38|P-value:5.68E-14 ID:SGTC_238|Compound:5hr heat shock (37°C) + nsc-638432|FD-Score:4.74|P-value:9.24E-5 ID:SGTC_280|Compound:3448-3607|FD-Score:4.80|P-value:7.65E-5 ID:SGTC_297|Compound:0986-0032|FD-Score:7.88|P-value:2.27E-10 ID:SGTC_301|Compound:4119-0100|FD-Score:5.23|P-value:1.81E-5 ID:SGTC_344|Compound:k064-0035|FD-Score:6.93|P-value:2.10E-8 ID:SGTC_348|Compound:k064-0012|FD-Score:3.99|P-value:8.43E-4 ID:SGTC_359|Compound:0081-0058|FD-Score:11.40|P-value:5.77E-20 ID:SGTC_403|Compound:arphamenine a|FD-Score:10.60|P-value:1.80E-17 ID:SGTC_425|Compound:3825-7017|FD-Score:13.00|P-value:3.55E-25 ID:SGTC_429|Compound:1112-0049|FD-Score:4.85|P-value:6.47E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:5.54|P-value:6.16E-6 ID:SGTC_447|Compound:ml7|FD-Score:4.18|P-value:5.02E-4 ID:SGTC_460|Compound:trequinsin|FD-Score:4.50|P-value:1.96E-4 ID:SGTC_522|Compound:1273-0010|FD-Score:4.94|P-value:4.86E-5 ID:SGTC_538|Compound:2922-0838|FD-Score:4.02|P-value:7.77E-4 ID:SGTC_545|Compound:4218-0007|FD-Score:4.35|P-value:3.07E-4 ID:SGTC_558|Compound:k064-0027|FD-Score:11.70|P-value:6.52E-21 ID:SGTC_570|Compound:0987-0065|FD-Score:7.80|P-value:3.33E-10 ID:SGTC_579|Compound:4491-1009|FD-Score:13.10|P-value:1.41E-25 ID:SGTC_602|Compound:3130-1533|FD-Score:6.45|P-value:1.73E-7 ID:SGTC_618|Compound:k072-0232|FD-Score:24.30|P-value:4.61E-83 ID:SGTC_623|Compound:k072-0108|FD-Score:18.50|P-value:5.07E-49 ID:SGTC_631|Compound:k072-0230|FD-Score:8.38|P-value:1.62E-11 ID:SGTC_645|Compound:0845-0943|FD-Score:9.26|P-value:1.13E-13 ID:SGTC_646|Compound:4092-0839|FD-Score:5.26|P-value:1.64E-5 ID:SGTC_665|Compound:3914-0008|FD-Score:9.85|P-value:3.00E-15 ID:SGTC_684|Compound:1140-0066|FD-Score:5.64|P-value:4.25E-6 ID:SGTC_685|Compound:1278-0033|FD-Score:7.56|P-value:1.11E-9 ID:SGTC_686|Compound:1319-0111|FD-Score:4.38|P-value:2.83E-4 ID:SGTC_706|Compound:4262-0057|FD-Score:10.90|P-value:3.76E-18 ID:SGTC_722|Compound:3534-0461|FD-Score:4.24|P-value:4.16E-4 ID:SGTC_765|Compound:1319-0117|FD-Score:23.00|P-value:4.60E-75 ID:SGTC_773|Compound:4358-1457|FD-Score:11.10|P-value:6.72E-19 ID:SGTC_799|Compound:1310-0557|FD-Score:5.36|P-value:1.19E-5 ID:SGTC_810|Compound:3825-7150|FD-Score:18.00|P-value:9.65E-47 ID:SGTC_866|Compound:0495-0101|FD-Score:12.30|P-value:1.19E-22 ID:SGTC_918|Compound:glabranin|FD-Score:6.40|P-value:2.09E-7 ID:SGTC_920|Compound:mycophenolic acid|FD-Score:4.50|P-value:1.96E-4 ID:SGTC_924|Compound:2046-0044|FD-Score:5.93|P-value:1.40E-6 ID:SGTC_934|Compound:2950-0684|FD-Score:4.84|P-value:6.67E-5 ID:SGTC_936|Compound:3005-4620|FD-Score:4.13|P-value:5.71E-4 ID:SGTC_946|Compound:3434-1334|FD-Score:4.95|P-value:4.77E-5 ID:SGTC_948|Compound:3448-0295|FD-Score:5.40|P-value:1.01E-5 ID:SGTC_953|Compound:1188-0045|FD-Score:6.92|P-value:2.24E-8 ID:SGTC_972|Compound:1319-0219|FD-Score:7.25|P-value:4.90E-9 ID:SGTC_976|Compound:1348-1067|FD-Score:16.60|P-value:4.42E-40 ID:SGTC_985|Compound:1493-0307|FD-Score:-4.84|P-value:5.17E-5 ID:SGTC_989|Compound:1501-0895|FD-Score:-4.72|P-value:7.53E-5 ID:SGTC_990|Compound:3985-0011|FD-Score:13.10|P-value:1.01E-25 ID:SGTC_1010|Compound:4112-3296|FD-Score:4.14|P-value:5.50E-4 ID:SGTC_1015|Compound:4130-4525|FD-Score:5.64|P-value:4.31E-6 ID:SGTC_1033|Compound:k072-0102|FD-Score:11.00|P-value:1.45E-18 ID:SGTC_1061|Compound:3448-9325|FD-Score:4.52|P-value:1.82E-4 ID:SGTC_1065|Compound:prochlorperazine maleate|FD-Score:5.00|P-value:3.94E-5 ID:SGTC_1068|Compound:loratadine|FD-Score:8.72|P-value:2.49E-12 ID:SGTC_1070|Compound:indatraline|FD-Score:22.20|P-value:5.20E-70 ID:SGTC_1071|Compound:trifluoperazine|FD-Score:9.23|P-value:1.38E-13 ID:SGTC_1081|Compound:sertraline|FD-Score:16.50|P-value:1.35E-39 ID:SGTC_1092|Compound:toremifene|FD-Score:5.48|P-value:7.71E-6 ID:SGTC_1093|Compound:fluphenazine|FD-Score:5.46|P-value:8.03E-6 ID:SGTC_1107|Compound:amlodipine|FD-Score:6.36|P-value:2.50E-7 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.83|P-value:2.09E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:5.68|P-value:3.64E-6 ID:SGTC_1143|Compound:3454-2408|FD-Score:4.76|P-value:8.60E-5 ID:SGTC_1151|Compound:3909-8316|FD-Score:4.53|P-value:1.77E-4 ID:SGTC_1152|Compound:3909-8331|FD-Score:5.55|P-value:5.92E-6 ID:SGTC_1185|Compound:1319-0113|FD-Score:4.11|P-value:6.11E-4 ID:SGTC_1186|Compound:1319-0216|FD-Score:7.27|P-value:4.49E-9 ID:SGTC_1206|Compound:3978-0017|FD-Score:8.67|P-value:3.45E-12 ID:SGTC_1209|Compound:2323-2347|FD-Score:5.93|P-value:1.39E-6 ID:SGTC_1226|Compound:3909-7979|FD-Score:6.23|P-value:4.25E-7 ID:SGTC_1240|Compound:0356-0016|FD-Score:4.26|P-value:3.94E-4 ID:SGTC_1247|Compound:0448-0043|FD-Score:15.40|P-value:1.05E-34 ID:SGTC_1269|Compound:0831-0796|FD-Score:7.41|P-value:2.26E-9 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.48|P-value:2.07E-4 ID:SGTC_1293|Compound:1000-1278|FD-Score:5.04|P-value:3.49E-5 ID:SGTC_1306|Compound:1185-0270|FD-Score:5.11|P-value:2.75E-5 ID:SGTC_1315|Compound:1237-0019|FD-Score:4.23|P-value:4.30E-4 ID:SGTC_1383|Compound:3049-0032|FD-Score:8.21|P-value:4.19E-11 ID:SGTC_1392|Compound:3455-1037|FD-Score:7.61|P-value:8.56E-10 ID:SGTC_1393|Compound:3470-5649|FD-Score:6.81|P-value:3.63E-8 ID:SGTC_1403|Compound:3909-7815|FD-Score:6.37|P-value:2.42E-7 ID:SGTC_1404|Compound:3909-7820|FD-Score:8.17|P-value:5.18E-11 ID:SGTC_1405|Compound:3909-7894|FD-Score:5.91|P-value:1.55E-6 ID:SGTC_1406|Compound:3909-7906|FD-Score:6.60|P-value:9.04E-8 ID:SGTC_1407|Compound:3909-7909|FD-Score:6.74|P-value:5.06E-8 ID:SGTC_1408|Compound:3909-7976|FD-Score:5.14|P-value:2.53E-5 ID:SGTC_1492|Compound:4158-0558|FD-Score:6.95|P-value:1.99E-8 ID:SGTC_1494|Compound:4358-1428|FD-Score:7.01|P-value:1.50E-8 ID:SGTC_1504|Compound:k297-0033|FD-Score:-4.44|P-value:1.84E-4 ID:SGTC_1510|Compound:1123-0200|FD-Score:5.66|P-value:4.00E-6 ID:SGTC_1516|Compound:st013856|FD-Score:-5.73|P-value:2.22E-6 ID:SGTC_1522|Compound:st012842|FD-Score:15.90|P-value:5.56E-37 ID:SGTC_1523|Compound:st012844|FD-Score:4.31|P-value:3.44E-4 ID:SGTC_1573|Compound:oleylamine|FD-Score:6.17|P-value:5.37E-7 ID:SGTC_1592|Compound:4',5'-dihydroxyflavone|FD-Score:11.70|P-value:1.23E-20 ID:SGTC_1604|Compound:st002052|FD-Score:4.31|P-value:3.47E-4 ID:SGTC_1605|Compound:st000082|FD-Score:4.87|P-value:6.12E-5 ID:SGTC_1606|Compound:st000094|FD-Score:4.33|P-value:3.20E-4 ID:SGTC_1612|Compound:st002233|FD-Score:6.16|P-value:5.69E-7 ID:SGTC_1619|Compound:st003326|FD-Score:5.63|P-value:4.40E-6 ID:SGTC_1628|Compound:st004252|FD-Score:9.38|P-value:5.67E-14 ID:SGTC_1663|Compound:st014140|FD-Score:4.97|P-value:4.44E-5 ID:SGTC_1664|Compound:st014217|FD-Score:4.99|P-value:4.17E-5 ID:SGTC_1675|Compound:st018485|FD-Score:6.92|P-value:2.21E-8 ID:SGTC_1676|Compound:st018489|FD-Score:7.82|P-value:3.12E-10 ID:SGTC_1678|Compound:st019265|FD-Score:5.35|P-value:1.19E-5 ID:SGTC_1721|Compound:st082152|FD-Score:7.99|P-value:1.30E-10 ID:SGTC_1725|Compound:st036284|FD-Score:-4.03|P-value:6.10E-4 ID:SGTC_1733|Compound:st037357|FD-Score:17.50|P-value:3.28E-44 ID:SGTC_1734|Compound:st037168|FD-Score:5.74|P-value:2.91E-6 ID:SGTC_1742|Compound:st038235|FD-Score:4.87|P-value:6.13E-5 ID:SGTC_1755|Compound:st041960|FD-Score:6.78|P-value:4.22E-8 ID:SGTC_1759|Compound:st043059|FD-Score:6.23|P-value:4.20E-7 ID:SGTC_1775|Compound:st081588|FD-Score:24.30|P-value:3.05E-83 ID:SGTC_1786|Compound:berberine|FD-Score:14.40|P-value:1.99E-30 ID:SGTC_1807|Compound:st050092|FD-Score:4.44|P-value:2.33E-4 ID:SGTC_1827|Compound:berberine|FD-Score:11.20|P-value:2.52E-19 ID:SGTC_1829|Compound:berberine|FD-Score:13.90|P-value:1.16E-28 ID:SGTC_1852|Compound:st056254|FD-Score:5.51|P-value:6.79E-6 ID:SGTC_1855|Compound:st056195|FD-Score:8.48|P-value:9.48E-12 ID:SGTC_1861|Compound:st057647|FD-Score:4.76|P-value:8.77E-5 ID:SGTC_1865|Compound:st057639|FD-Score:4.62|P-value:1.34E-4 ID:SGTC_1867|Compound:st057372|FD-Score:4.91|P-value:5.36E-5 ID:SGTC_1886|Compound:st057356|FD-Score:6.15|P-value:5.81E-7 ID:SGTC_1908|Compound:st060353|FD-Score:4.02|P-value:7.73E-4 ID:SGTC_1924|Compound:st058459|FD-Score:8.14|P-value:5.93E-11 ID:SGTC_1940|Compound:st075990|FD-Score:5.56|P-value:5.66E-6 ID:SGTC_1945|Compound:st075991|FD-Score:5.59|P-value:5.02E-6 ID:SGTC_1958|Compound:st076513|FD-Score:25.20|P-value:1.71E-89 ID:SGTC_1971|Compound:st069429|FD-Score:11.90|P-value:2.33E-21 ID:SGTC_1990|Compound:st072050|FD-Score:4.87|P-value:6.18E-5 ID:SGTC_1999|Compound:st074831|FD-Score:5.18|P-value:2.21E-5 ID:SGTC_2037|Compound:5169046|FD-Score:4.30|P-value:3.51E-4 ID:SGTC_2038|Compound:4100038|FD-Score:6.17|P-value:5.44E-7 ID:SGTC_2075|Compound:5212009|FD-Score:4.70|P-value:1.05E-4 ID:SGTC_2078|Compound:5212016|FD-Score:10.80|P-value:6.65E-18 ID:SGTC_2100|Compound:5377183|FD-Score:10.20|P-value:4.28E-16 ID:SGTC_2131|Compound:toluylene red|FD-Score:10.80|P-value:7.21E-18 ID:SGTC_2149|Compound:5554786|FD-Score:-4.13|P-value:4.55E-4 ID:SGTC_2160|Compound:5660466|FD-Score:7.09|P-value:1.03E-8 ID:SGTC_2168|Compound:5727979|FD-Score:4.02|P-value:7.68E-4 ID:SGTC_2204|Compound:7233102|FD-Score:7.72|P-value:5.16E-10 ID:SGTC_2206|Compound:7254556|FD-Score:10.40|P-value:1.14E-16 ID:SGTC_2260|Compound:7964312|FD-Score:4.51|P-value:1.92E-4 ID:SGTC_2296|Compound:7971656|FD-Score:5.39|P-value:1.06E-5 ID:SGTC_2305|Compound:7443522|FD-Score:6.02|P-value:9.90E-7 ID:SGTC_2330|Compound:7979373|FD-Score:10.00|P-value:1.21E-15 ID:SGTC_2338|Compound:7999974|FD-Score:8.70|P-value:2.91E-12 ID:SGTC_2382|Compound:9035899|FD-Score:7.24|P-value:5.10E-9 ID:SGTC_2385|Compound:9074692|FD-Score:6.61|P-value:8.56E-8 ID:SGTC_2404|Compound:5161160|FD-Score:8.77|P-value:1.95E-12 ID:SGTC_2424|Compound:5537928|FD-Score:5.23|P-value:1.84E-5 ID:SGTC_2462|Compound:5162487|FD-Score:5.14|P-value:2.54E-5 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:5.64|P-value:4.20E-6 ID:SGTC_2511|Compound:berberine|FD-Score:11.70|P-value:1.24E-20 ID:SGTC_2512|Compound:diallyl trisulfide|FD-Score:4.44|P-value:2.34E-4 ID:SGTC_2513|Compound:baicalein|FD-Score:-4.00|P-value:6.54E-4 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:7.79|P-value:3.61E-10 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:4.60|P-value:1.45E-4 ID:SGTC_2590|Compound:3,4',5',6',7'-pentamethoxyflavone|FD-Score:10.40|P-value:1.07E-16 ID:SGTC_2593|Compound:nobiletin|FD-Score:6.24|P-value:4.17E-7 ID:SGTC_2600|Compound:tangeritin|FD-Score:4.25|P-value:4.13E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:5.93|P-value:1.43E-6 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:4.77|P-value:8.48E-5 ID:SGTC_2698|Compound:st077697|FD-Score:5.66|P-value:3.97E-6 ID:SGTC_2699|Compound:st077704|FD-Score:10.10|P-value:7.55E-16 ID:SGTC_2703|Compound:st077852|FD-Score:6.04|P-value:9.11E-7 ID:SGTC_2716|Compound:st080858|FD-Score:10.20|P-value:3.91E-16 ID:SGTC_2724|Compound:maprotiline|FD-Score:5.80|P-value:2.32E-6 ID:SGTC_2729|Compound:fluphenazine|FD-Score:7.49|P-value:1.58E-9 ID:SGTC_2744|Compound:captopril|FD-Score:6.32|P-value:2.93E-7 ID:SGTC_2755|Compound:lomerizine|FD-Score:4.01|P-value:7.92E-4 ID:SGTC_2757|Compound:clomiphene|FD-Score:5.11|P-value:2.75E-5 ID:SGTC_2769|Compound:toremifene|FD-Score:4.46|P-value:2.19E-4 ID:SGTC_2772|Compound:vinpocetine|FD-Score:6.14|P-value:6.26E-7 ID:SGTC_2774|Compound:tamoxifen|FD-Score:8.22|P-value:3.94E-11 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:4.31|P-value:3.41E-4 ID:SGTC_2796|Compound:7949634|FD-Score:5.07|P-value:3.14E-5 ID:SGTC_2797|Compound:7859098|FD-Score:4.49|P-value:2.00E-4 ID:SGTC_2809|Compound:7964133|FD-Score:13.50|P-value:3.29E-27 ID:SGTC_2811|Compound:7967822|FD-Score:4.68|P-value:1.14E-4 ID:SGTC_2818|Compound:7996756|FD-Score:5.88|P-value:1.68E-6 ID:SGTC_2820|Compound:7989630|FD-Score:3.98|P-value:8.66E-4 ID:SGTC_2909|Compound:7941780|FD-Score:4.01|P-value:8.09E-4 ID:SGTC_2913|Compound:7966556|FD-Score:7.37|P-value:2.82E-9 ID:SGTC_2937|Compound:9044753|FD-Score:16.90|P-value:2.12E-41 ID:SGTC_2938|Compound:9059746|FD-Score:4.16|P-value:5.25E-4 ID:SGTC_2939|Compound:9044578|FD-Score:5.98|P-value:1.15E-6 ID:SGTC_2967|Compound:9089538|FD-Score:6.71|P-value:5.74E-8 ID:SGTC_2968|Compound:9090663|FD-Score:7.12|P-value:8.99E-9 ID:SGTC_2983|Compound:9022671|FD-Score:10.80|P-value:5.35E-18 ID:SGTC_2993|Compound:9054257|FD-Score:5.97|P-value:1.20E-6 ID:SGTC_3025|Compound:9087895|FD-Score:4.32|P-value:3.34E-4 ID:SGTC_3026|Compound:9090633|FD-Score:5.36|P-value:1.15E-5 ID:SGTC_3027|Compound:9089541|FD-Score:6.83|P-value:3.35E-8 ID:SGTC_3032|Compound:9089427|FD-Score:8.76|P-value:2.05E-12 ID:SGTC_3034|Compound:9090421|FD-Score:6.31|P-value:3.05E-7 ID:SGTC_3038|Compound:9091290|FD-Score:4.12|P-value:5.90E-4 ID:SGTC_3069|Compound:9117009|FD-Score:4.82|P-value:7.24E-5 ID:SGTC_3073|Compound:9114972|FD-Score:4.46|P-value:2.23E-4 ID:SGTC_3093|Compound:9117344|FD-Score:4.45|P-value:2.29E-4 ID:SGTC_3100|Compound:9120536|FD-Score:10.40|P-value:9.21E-17 ID:SGTC_3101|Compound:9120531|FD-Score:8.73|P-value:2.46E-12 ID:SGTC_3103|Compound:9120822|FD-Score:-4.41|P-value:2.02E-4 ID:SGTC_3126|Compound:9127922|FD-Score:8.02|P-value:1.10E-10 ID:SGTC_3168|Compound:9103419|FD-Score:4.13|P-value:5.71E-4 ID:SGTC_3170|Compound:9103054|FD-Score:9.38|P-value:5.54E-14 ID:SGTC_3185|Compound:9108267|FD-Score:8.04|P-value:9.99E-11 ID:SGTC_3195|Compound:9113082|FD-Score:7.44|P-value:2.03E-9 ID:SGTC_3222|Compound:9128301|FD-Score:12.10|P-value:4.37E-22 ID:SGTC_3249|Compound:9135183|FD-Score:7.62|P-value:8.21E-10 ID:SGTC_3251|Compound:9135047|FD-Score:4.76|P-value:8.68E-5 ID:SGTC_3253|Compound:9135987|FD-Score:4.77|P-value:8.56E-5 ID:SGTC_3257|Compound:9139206|FD-Score:4.59|P-value:1.47E-4 ID:SGTC_3259|Compound:9138485|FD-Score:5.60|P-value:4.84E-6 ID:SGTC_3260|Compound:9137109|FD-Score:4.46|P-value:2.19E-4 ID:SGTC_3276|Compound:9139060|FD-Score:7.08|P-value:1.10E-8 ID:SGTC_3280|Compound:9140961|FD-Score:12.10|P-value:4.84E-22 ID:SGTC_3296|Compound:9122258|FD-Score:6.41|P-value:2.05E-7 ID:SGTC_49|Compound:0717-0965|FD-Score:15.90|P-value:6.65E-37 ID:SGTC_57|Compound:miconazole|FD-Score:-5.18|P-value:1.63E-5 ID:SGTC_62|Compound:0180-0423|FD-Score:14.10|P-value:2.27E-29 ID:SGTC_85|Compound:0868-0259|FD-Score:9.57|P-value:1.80E-14 ID:SGTC_97|Compound:0535-0701|FD-Score:23.90|P-value:1.65E-80 ID:SGTC_100|Compound:0086-0128|FD-Score:4.29|P-value:3.67E-4 ID:SGTC_115|Compound:0527-0192|FD-Score:4.55|P-value:1.66E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:11.90|P-value:2.11E-21 ID:SGTC_121|Compound:0557-0495|FD-Score:11.00|P-value:1.15E-18 ID:SGTC_135|Compound:0933-0004|FD-Score:15.70|P-value:5.63E-36 ID:SGTC_136|Compound:0097-0015|FD-Score:8.79|P-value:1.74E-12 ID:SGTC_160|Compound:3453-0671|FD-Score:8.09|P-value:7.83E-11 ID:SGTC_167|Compound:3672-0051|FD-Score:4.59|P-value:1.50E-4 ID:SGTC_171|Compound:k064-0041|FD-Score:12.80|P-value:1.57E-24 ID:SGTC_183|Compound:3914-0051|FD-Score:12.00|P-value:7.24E-22 ID:SGTC_191|Compound:3914-0123|FD-Score:6.76|P-value:4.52E-8 ID:SGTC_198|Compound:3454-2873|FD-Score:9.38|P-value:5.68E-14 ID:SGTC_238|Compound:5hr heat shock (37°C) + nsc-638432|FD-Score:4.74|P-value:9.24E-5 ID:SGTC_280|Compound:3448-3607|FD-Score:4.80|P-value:7.65E-5 ID:SGTC_297|Compound:0986-0032|FD-Score:7.88|P-value:2.27E-10 ID:SGTC_301|Compound:4119-0100|FD-Score:5.23|P-value:1.81E-5 ID:SGTC_344|Compound:k064-0035|FD-Score:6.93|P-value:2.10E-8 ID:SGTC_348|Compound:k064-0012|FD-Score:3.99|P-value:8.43E-4 ID:SGTC_359|Compound:0081-0058|FD-Score:11.40|P-value:5.77E-20 ID:SGTC_403|Compound:arphamenine a|FD-Score:10.60|P-value:1.80E-17 ID:SGTC_425|Compound:3825-7017|FD-Score:13.00|P-value:3.55E-25 ID:SGTC_429|Compound:1112-0049|FD-Score:4.85|P-value:6.47E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:5.54|P-value:6.16E-6 ID:SGTC_447|Compound:ml7|FD-Score:4.18|P-value:5.02E-4 ID:SGTC_460|Compound:trequinsin|FD-Score:4.50|P-value:1.96E-4 ID:SGTC_522|Compound:1273-0010|FD-Score:4.94|P-value:4.86E-5 ID:SGTC_538|Compound:2922-0838|FD-Score:4.02|P-value:7.77E-4 ID:SGTC_545|Compound:4218-0007|FD-Score:4.35|P-value:3.07E-4 ID:SGTC_558|Compound:k064-0027|FD-Score:11.70|P-value:6.52E-21 ID:SGTC_570|Compound:0987-0065|FD-Score:7.80|P-value:3.33E-10 ID:SGTC_579|Compound:4491-1009|FD-Score:13.10|P-value:1.41E-25 ID:SGTC_602|Compound:3130-1533|FD-Score:6.45|P-value:1.73E-7 ID:SGTC_618|Compound:k072-0232|FD-Score:24.30|P-value:4.61E-83 ID:SGTC_623|Compound:k072-0108|FD-Score:18.50|P-value:5.07E-49 ID:SGTC_631|Compound:k072-0230|FD-Score:8.38|P-value:1.62E-11 ID:SGTC_645|Compound:0845-0943|FD-Score:9.26|P-value:1.13E-13 ID:SGTC_646|Compound:4092-0839|FD-Score:5.26|P-value:1.64E-5 ID:SGTC_665|Compound:3914-0008|FD-Score:9.85|P-value:3.00E-15 ID:SGTC_684|Compound:1140-0066|FD-Score:5.64|P-value:4.25E-6 ID:SGTC_685|Compound:1278-0033|FD-Score:7.56|P-value:1.11E-9 ID:SGTC_686|Compound:1319-0111|FD-Score:4.38|P-value:2.83E-4 ID:SGTC_706|Compound:4262-0057|FD-Score:10.90|P-value:3.76E-18 ID:SGTC_722|Compound:3534-0461|FD-Score:4.24|P-value:4.16E-4 ID:SGTC_765|Compound:1319-0117|FD-Score:23.00|P-value:4.60E-75 ID:SGTC_773|Compound:4358-1457|FD-Score:11.10|P-value:6.72E-19 ID:SGTC_799|Compound:1310-0557|FD-Score:5.36|P-value:1.19E-5 ID:SGTC_810|Compound:3825-7150|FD-Score:18.00|P-value:9.65E-47 ID:SGTC_866|Compound:0495-0101|FD-Score:12.30|P-value:1.19E-22 ID:SGTC_918|Compound:glabranin|FD-Score:6.40|P-value:2.09E-7 ID:SGTC_920|Compound:mycophenolic acid|FD-Score:4.50|P-value:1.96E-4 ID:SGTC_924|Compound:2046-0044|FD-Score:5.93|P-value:1.40E-6 ID:SGTC_934|Compound:2950-0684|FD-Score:4.84|P-value:6.67E-5 ID:SGTC_936|Compound:3005-4620|FD-Score:4.13|P-value:5.71E-4 ID:SGTC_946|Compound:3434-1334|FD-Score:4.95|P-value:4.77E-5 ID:SGTC_948|Compound:3448-0295|FD-Score:5.40|P-value:1.01E-5 ID:SGTC_953|Compound:1188-0045|FD-Score:6.92|P-value:2.24E-8 ID:SGTC_972|Compound:1319-0219|FD-Score:7.25|P-value:4.90E-9 ID:SGTC_976|Compound:1348-1067|FD-Score:16.60|P-value:4.42E-40 ID:SGTC_985|Compound:1493-0307|FD-Score:-4.84|P-value:5.17E-5 ID:SGTC_989|Compound:1501-0895|FD-Score:-4.72|P-value:7.53E-5 ID:SGTC_990|Compound:3985-0011|FD-Score:13.10|P-value:1.01E-25 ID:SGTC_1010|Compound:4112-3296|FD-Score:4.14|P-value:5.50E-4 ID:SGTC_1015|Compound:4130-4525|FD-Score:5.64|P-value:4.31E-6 ID:SGTC_1033|Compound:k072-0102|FD-Score:11.00|P-value:1.45E-18 ID:SGTC_1061|Compound:3448-9325|FD-Score:4.52|P-value:1.82E-4 ID:SGTC_1065|Compound:prochlorperazine maleate|FD-Score:5.00|P-value:3.94E-5 ID:SGTC_1068|Compound:loratadine|FD-Score:8.72|P-value:2.49E-12 ID:SGTC_1070|Compound:indatraline|FD-Score:22.20|P-value:5.20E-70 ID:SGTC_1071|Compound:trifluoperazine|FD-Score:9.23|P-value:1.38E-13 ID:SGTC_1081|Compound:sertraline|FD-Score:16.50|P-value:1.35E-39 ID:SGTC_1092|Compound:toremifene|FD-Score:5.48|P-value:7.71E-6 ID:SGTC_1093|Compound:fluphenazine|FD-Score:5.46|P-value:8.03E-6 ID:SGTC_1107|Compound:amlodipine|FD-Score:6.36|P-value:2.50E-7 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.83|P-value:2.09E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:5.68|P-value:3.64E-6 ID:SGTC_1143|Compound:3454-2408|FD-Score:4.76|P-value:8.60E-5 ID:SGTC_1151|Compound:3909-8316|FD-Score:4.53|P-value:1.77E-4 ID:SGTC_1152|Compound:3909-8331|FD-Score:5.55|P-value:5.92E-6 ID:SGTC_1185|Compound:1319-0113|FD-Score:4.11|P-value:6.11E-4 ID:SGTC_1186|Compound:1319-0216|FD-Score:7.27|P-value:4.49E-9 ID:SGTC_1206|Compound:3978-0017|FD-Score:8.67|P-value:3.45E-12 ID:SGTC_1209|Compound:2323-2347|FD-Score:5.93|P-value:1.39E-6 ID:SGTC_1226|Compound:3909-7979|FD-Score:6.23|P-value:4.25E-7 ID:SGTC_1240|Compound:0356-0016|FD-Score:4.26|P-value:3.94E-4 ID:SGTC_1247|Compound:0448-0043|FD-Score:15.40|P-value:1.05E-34 ID:SGTC_1269|Compound:0831-0796|FD-Score:7.41|P-value:2.26E-9 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.48|P-value:2.07E-4 ID:SGTC_1293|Compound:1000-1278|FD-Score:5.04|P-value:3.49E-5 ID:SGTC_1306|Compound:1185-0270|FD-Score:5.11|P-value:2.75E-5 ID:SGTC_1315|Compound:1237-0019|FD-Score:4.23|P-value:4.30E-4 ID:SGTC_1383|Compound:3049-0032|FD-Score:8.21|P-value:4.19E-11 ID:SGTC_1392|Compound:3455-1037|FD-Score:7.61|P-value:8.56E-10 ID:SGTC_1393|Compound:3470-5649|FD-Score:6.81|P-value:3.63E-8 ID:SGTC_1403|Compound:3909-7815|FD-Score:6.37|P-value:2.42E-7 ID:SGTC_1404|Compound:3909-7820|FD-Score:8.17|P-value:5.18E-11 ID:SGTC_1405|Compound:3909-7894|FD-Score:5.91|P-value:1.55E-6 ID:SGTC_1406|Compound:3909-7906|FD-Score:6.60|P-value:9.04E-8 ID:SGTC_1407|Compound:3909-7909|FD-Score:6.74|P-value:5.06E-8 ID:SGTC_1408|Compound:3909-7976|FD-Score:5.14|P-value:2.53E-5 ID:SGTC_1492|Compound:4158-0558|FD-Score:6.95|P-value:1.99E-8 ID:SGTC_1494|Compound:4358-1428|FD-Score:7.01|P-value:1.50E-8 ID:SGTC_1504|Compound:k297-0033|FD-Score:-4.44|P-value:1.84E-4 ID:SGTC_1510|Compound:1123-0200|FD-Score:5.66|P-value:4.00E-6 ID:SGTC_1516|Compound:st013856|FD-Score:-5.73|P-value:2.22E-6 ID:SGTC_1522|Compound:st012842|FD-Score:15.90|P-value:5.56E-37 ID:SGTC_1523|Compound:st012844|FD-Score:4.31|P-value:3.44E-4 ID:SGTC_1573|Compound:oleylamine|FD-Score:6.17|P-value:5.37E-7 ID:SGTC_1592|Compound:4',5'-dihydroxyflavone|FD-Score:11.70|P-value:1.23E-20 ID:SGTC_1604|Compound:st002052|FD-Score:4.31|P-value:3.47E-4 ID:SGTC_1605|Compound:st000082|FD-Score:4.87|P-value:6.12E-5 ID:SGTC_1606|Compound:st000094|FD-Score:4.33|P-value:3.20E-4 ID:SGTC_1612|Compound:st002233|FD-Score:6.16|P-value:5.69E-7 ID:SGTC_1619|Compound:st003326|FD-Score:5.63|P-value:4.40E-6 ID:SGTC_1628|Compound:st004252|FD-Score:9.38|P-value:5.67E-14 ID:SGTC_1663|Compound:st014140|FD-Score:4.97|P-value:4.44E-5 ID:SGTC_1664|Compound:st014217|FD-Score:4.99|P-value:4.17E-5 ID:SGTC_1675|Compound:st018485|FD-Score:6.92|P-value:2.21E-8 ID:SGTC_1676|Compound:st018489|FD-Score:7.82|P-value:3.12E-10 ID:SGTC_1678|Compound:st019265|FD-Score:5.35|P-value:1.19E-5 ID:SGTC_1721|Compound:st082152|FD-Score:7.99|P-value:1.30E-10 ID:SGTC_1725|Compound:st036284|FD-Score:-4.03|P-value:6.10E-4 ID:SGTC_1733|Compound:st037357|FD-Score:17.50|P-value:3.28E-44 ID:SGTC_1734|Compound:st037168|FD-Score:5.74|P-value:2.91E-6 ID:SGTC_1742|Compound:st038235|FD-Score:4.87|P-value:6.13E-5 ID:SGTC_1755|Compound:st041960|FD-Score:6.78|P-value:4.22E-8 ID:SGTC_1759|Compound:st043059|FD-Score:6.23|P-value:4.20E-7 ID:SGTC_1775|Compound:st081588|FD-Score:24.30|P-value:3.05E-83 ID:SGTC_1786|Compound:berberine|FD-Score:14.40|P-value:1.99E-30 ID:SGTC_1807|Compound:st050092|FD-Score:4.44|P-value:2.33E-4 ID:SGTC_1827|Compound:berberine|FD-Score:11.20|P-value:2.52E-19 ID:SGTC_1829|Compound:berberine|FD-Score:13.90|P-value:1.16E-28 ID:SGTC_1852|Compound:st056254|FD-Score:5.51|P-value:6.79E-6 ID:SGTC_1855|Compound:st056195|FD-Score:8.48|P-value:9.48E-12 ID:SGTC_1861|Compound:st057647|FD-Score:4.76|P-value:8.77E-5 ID:SGTC_1865|Compound:st057639|FD-Score:4.62|P-value:1.34E-4 ID:SGTC_1867|Compound:st057372|FD-Score:4.91|P-value:5.36E-5 ID:SGTC_1886|Compound:st057356|FD-Score:6.15|P-value:5.81E-7 ID:SGTC_1908|Compound:st060353|FD-Score:4.02|P-value:7.73E-4 ID:SGTC_1924|Compound:st058459|FD-Score:8.14|P-value:5.93E-11 ID:SGTC_1940|Compound:st075990|FD-Score:5.56|P-value:5.66E-6 ID:SGTC_1945|Compound:st075991|FD-Score:5.59|P-value:5.02E-6 ID:SGTC_1958|Compound:st076513|FD-Score:25.20|P-value:1.71E-89 ID:SGTC_1971|Compound:st069429|FD-Score:11.90|P-value:2.33E-21 ID:SGTC_1990|Compound:st072050|FD-Score:4.87|P-value:6.18E-5 ID:SGTC_1999|Compound:st074831|FD-Score:5.18|P-value:2.21E-5 ID:SGTC_2037|Compound:5169046|FD-Score:4.30|P-value:3.51E-4 ID:SGTC_2038|Compound:4100038|FD-Score:6.17|P-value:5.44E-7 ID:SGTC_2075|Compound:5212009|FD-Score:4.70|P-value:1.05E-4 ID:SGTC_2078|Compound:5212016|FD-Score:10.80|P-value:6.65E-18 ID:SGTC_2100|Compound:5377183|FD-Score:10.20|P-value:4.28E-16 ID:SGTC_2131|Compound:toluylene red|FD-Score:10.80|P-value:7.21E-18 ID:SGTC_2149|Compound:5554786|FD-Score:-4.13|P-value:4.55E-4 ID:SGTC_2160|Compound:5660466|FD-Score:7.09|P-value:1.03E-8 ID:SGTC_2168|Compound:5727979|FD-Score:4.02|P-value:7.68E-4 ID:SGTC_2204|Compound:7233102|FD-Score:7.72|P-value:5.16E-10 ID:SGTC_2206|Compound:7254556|FD-Score:10.40|P-value:1.14E-16 ID:SGTC_2260|Compound:7964312|FD-Score:4.51|P-value:1.92E-4 ID:SGTC_2296|Compound:7971656|FD-Score:5.39|P-value:1.06E-5 ID:SGTC_2305|Compound:7443522|FD-Score:6.02|P-value:9.90E-7 ID:SGTC_2330|Compound:7979373|FD-Score:10.00|P-value:1.21E-15 ID:SGTC_2338|Compound:7999974|FD-Score:8.70|P-value:2.91E-12 ID:SGTC_2382|Compound:9035899|FD-Score:7.24|P-value:5.10E-9 ID:SGTC_2385|Compound:9074692|FD-Score:6.61|P-value:8.56E-8 ID:SGTC_2404|Compound:5161160|FD-Score:8.77|P-value:1.95E-12 ID:SGTC_2424|Compound:5537928|FD-Score:5.23|P-value:1.84E-5 ID:SGTC_2462|Compound:5162487|FD-Score:5.14|P-value:2.54E-5 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:5.64|P-value:4.20E-6 ID:SGTC_2511|Compound:berberine|FD-Score:11.70|P-value:1.24E-20 ID:SGTC_2512|Compound:diallyl trisulfide|FD-Score:4.44|P-value:2.34E-4 ID:SGTC_2513|Compound:baicalein|FD-Score:-4.00|P-value:6.54E-4 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:7.79|P-value:3.61E-10 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:4.60|P-value:1.45E-4 ID:SGTC_2590|Compound:3,4',5',6',7'-pentamethoxyflavone|FD-Score:10.40|P-value:1.07E-16 ID:SGTC_2593|Compound:nobiletin|FD-Score:6.24|P-value:4.17E-7 ID:SGTC_2600|Compound:tangeritin|FD-Score:4.25|P-value:4.13E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:5.93|P-value:1.43E-6 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:4.77|P-value:8.48E-5 ID:SGTC_2698|Compound:st077697|FD-Score:5.66|P-value:3.97E-6 ID:SGTC_2699|Compound:st077704|FD-Score:10.10|P-value:7.55E-16 ID:SGTC_2703|Compound:st077852|FD-Score:6.04|P-value:9.11E-7 ID:SGTC_2716|Compound:st080858|FD-Score:10.20|P-value:3.91E-16 ID:SGTC_2724|Compound:maprotiline|FD-Score:5.80|P-value:2.32E-6 ID:SGTC_2729|Compound:fluphenazine|FD-Score:7.49|P-value:1.58E-9 ID:SGTC_2744|Compound:captopril|FD-Score:6.32|P-value:2.93E-7 ID:SGTC_2755|Compound:lomerizine|FD-Score:4.01|P-value:7.92E-4 ID:SGTC_2757|Compound:clomiphene|FD-Score:5.11|P-value:2.75E-5 ID:SGTC_2769|Compound:toremifene|FD-Score:4.46|P-value:2.19E-4 ID:SGTC_2772|Compound:vinpocetine|FD-Score:6.14|P-value:6.26E-7 ID:SGTC_2774|Compound:tamoxifen|FD-Score:8.22|P-value:3.94E-11 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:4.31|P-value:3.41E-4 ID:SGTC_2796|Compound:7949634|FD-Score:5.07|P-value:3.14E-5 ID:SGTC_2797|Compound:7859098|FD-Score:4.49|P-value:2.00E-4 ID:SGTC_2809|Compound:7964133|FD-Score:13.50|P-value:3.29E-27 ID:SGTC_2811|Compound:7967822|FD-Score:4.68|P-value:1.14E-4 ID:SGTC_2818|Compound:7996756|FD-Score:5.88|P-value:1.68E-6 ID:SGTC_2820|Compound:7989630|FD-Score:3.98|P-value:8.66E-4 ID:SGTC_2909|Compound:7941780|FD-Score:4.01|P-value:8.09E-4 ID:SGTC_2913|Compound:7966556|FD-Score:7.37|P-value:2.82E-9 ID:SGTC_2937|Compound:9044753|FD-Score:16.90|P-value:2.12E-41 ID:SGTC_2938|Compound:9059746|FD-Score:4.16|P-value:5.25E-4 ID:SGTC_2939|Compound:9044578|FD-Score:5.98|P-value:1.15E-6 ID:SGTC_2967|Compound:9089538|FD-Score:6.71|P-value:5.74E-8 ID:SGTC_2968|Compound:9090663|FD-Score:7.12|P-value:8.99E-9 ID:SGTC_2983|Compound:9022671|FD-Score:10.80|P-value:5.35E-18 ID:SGTC_2993|Compound:9054257|FD-Score:5.97|P-value:1.20E-6 ID:SGTC_3025|Compound:9087895|FD-Score:4.32|P-value:3.34E-4 ID:SGTC_3026|Compound:9090633|FD-Score:5.36|P-value:1.15E-5 ID:SGTC_3027|Compound:9089541|FD-Score:6.83|P-value:3.35E-8 ID:SGTC_3032|Compound:9089427|FD-Score:8.76|P-value:2.05E-12 ID:SGTC_3034|Compound:9090421|FD-Score:6.31|P-value:3.05E-7 ID:SGTC_3038|Compound:9091290|FD-Score:4.12|P-value:5.90E-4 ID:SGTC_3069|Compound:9117009|FD-Score:4.82|P-value:7.24E-5 ID:SGTC_3073|Compound:9114972|FD-Score:4.46|P-value:2.23E-4 ID:SGTC_3093|Compound:9117344|FD-Score:4.45|P-value:2.29E-4 ID:SGTC_3100|Compound:9120536|FD-Score:10.40|P-value:9.21E-17 ID:SGTC_3101|Compound:9120531|FD-Score:8.73|P-value:2.46E-12 ID:SGTC_3103|Compound:9120822|FD-Score:-4.41|P-value:2.02E-4 ID:SGTC_3126|Compound:9127922|FD-Score:8.02|P-value:1.10E-10 ID:SGTC_3168|Compound:9103419|FD-Score:4.13|P-value:5.71E-4 ID:SGTC_3170|Compound:9103054|FD-Score:9.38|P-value:5.54E-14 ID:SGTC_3185|Compound:9108267|FD-Score:8.04|P-value:9.99E-11 ID:SGTC_3195|Compound:9113082|FD-Score:7.44|P-value:2.03E-9 ID:SGTC_3222|Compound:9128301|FD-Score:12.10|P-value:4.37E-22 ID:SGTC_3249|Compound:9135183|FD-Score:7.62|P-value:8.21E-10 ID:SGTC_3251|Compound:9135047|FD-Score:4.76|P-value:8.68E-5 ID:SGTC_3253|Compound:9135987|FD-Score:4.77|P-value:8.56E-5 ID:SGTC_3257|Compound:9139206|FD-Score:4.59|P-value:1.47E-4 ID:SGTC_3259|Compound:9138485|FD-Score:5.60|P-value:4.84E-6 ID:SGTC_3260|Compound:9137109|FD-Score:4.46|P-value:2.19E-4 ID:SGTC_3276|Compound:9139060|FD-Score:7.08|P-value:1.10E-8 ID:SGTC_3280|Compound:9140961|FD-Score:12.10|P-value:4.84E-22 ID:SGTC_3296|Compound:9122258|FD-Score:6.41|P-value:2.05E-7

Top fitness defect scores for YGL099W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1958 st076513 25.20 41.9 µM 1.71E-89 60S ribosome export 1 1.29E-140 14.10
2 SGTC_1775 st081588 24.30 35.2 µM 3.05E-83 60S ribosome export 1 1.00E-130 13.10
3 SGTC_618 k072-0232 24.30 33.2 µM 4.61E-83 60S ribosome export 1 1.93E-130 16.20
4 SGTC_97 0535-0701 23.90 19.1 µM 1.65E-80 60S ribosome export 1 2.12E-126 12.50
5 SGTC_765 1319-0117 23.00 244.0 µM 4.60E-75 60S ribosome export 1 8.68E-118 12.70
6 SGTC_1070 indatraline 22.20 8.8 µM 5.20E-70 60S ribosome export 1 8.58E-110 14.80
7 SGTC_623 k072-0108 18.50 16.9 µM 5.07E-49 heme biosynthesis & mitochondrial translocase 1 1.36E-76 5.23
8 SGTC_810 3825-7150 18.00 143.0 µM 9.65E-47 60S ribosome export 1 5.49E-73 11.70
9 SGTC_1733 st037357 17.50 54.9 µM 3.28E-44 60S ribosome export 1 5.52E-69 9.47
10 SGTC_2937 9044753 16.90 11.3 µM 2.12E-41 60S ribosome export 1 1.54E-64 10.30
11 SGTC_976 1348-1067 16.60 47.6 µM 4.42E-40 60S ribosome export 1 1.88E-62 10.70
12 SGTC_1081 sertraline 16.50 6.0 µM 1.35E-39 60S ribosome export 1 1.10E-61 11.20
13 SGTC_1522 st012842 15.90 45.6 µM 5.56E-37 RNA pol III & RNase P/MRP 2 1.50E-57 8.43
14 SGTC_49 0717-0965 15.90 32.1 µM 6.65E-37 60S ribosome export 1 1.99E-57 9.12
15 SGTC_135 0933-0004 15.70 26.4 µM 5.63E-36 60S ribosome export 1 5.83E-56 7.01
16 SGTC_1247 0448-0043 15.40 5.8 µM 1.05E-34 ERG2 1 5.99E-54 6.02
17 SGTC_1786 berberine 14.40 21.6 µM 1.99E-30 60S ribosome export 2 3.45E-47 4.99
18 SGTC_62 0180-0423 14.10 3.2 µM 2.27E-29 60S ribosome export 1 1.62E-45 7.08
19 SGTC_1829 berberine 13.90 14.4 µM 1.16E-28 60S ribosome export 1 2.14E-44 3.71
20 SGTC_2809 7964133 13.50 13.0 µM 3.29E-27 60S ribosome export 1 4.23E-42 4.45

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.689 0 YHR170W NMD3 het Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex
0.303 3.60E-72 YOR072W_d YOR072W_d hom Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive
0.234 6.51E-43 YDR083W RRP8 hom Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1
0.192 4.34E-29 YOR279C RFM1 hom DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance
0.189 2.87E-28 YOL068C HST1 hom NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance
0.181 5.30E-26 YBR267W REI1 hom Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network
0.165 7.60E-22 YER112W LSM4 het Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; forms cytoplasmic foci upon DNA replication stress
0.160 9.85E-21 YPL093W NOG1 het Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
0.134 7.25E-15 YLR359W ADE13 het Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency
0.134 8.22E-15 YDR224C HTB1 het Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB2; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
0.131 2.22E-14 YDR310C SUM1 hom Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint
0.120 3.02E-12 YLR438C-A LSM3 het Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein increases in abundance and relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
0.118 6.25E-12 YNL182C IPI3 het Component of the Rix1 complex (Rix1p-Ipi1p-Ipi3p) and pre-replicative complexes (pre-RCs); required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-RC formation and maintenance during DNA replication licensing; highly conserved protein which contains several WD40 motifs; IPI3 is an essential gene
0.110 1.54E-10 YBL051C PIN4 hom Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage
0.109 2.08E-10 YCR100C_p YCR100C_p hom Putative protein of unknown function