YGR210C_p

Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

Zygosity: Homozygous strain
fixedexpanded
Profile for YGR210C / YGR210C

Click on Significant Values for Screen Details ID:SGTC_102|Compound:gallobenzophenone|FD-Score:3.55|P-value:8.14E-5 ID:SGTC_130|Compound:0136-0219|FD-Score:3.16|P-value:3.93E-4 ID:SGTC_164|Compound:4100-3994|FD-Score:3.05|P-value:6.01E-4 ID:SGTC_389|Compound:tpck|FD-Score:3.95|P-value:1.41E-5 ID:SGTC_864|Compound:0469-0573|FD-Score:3.33|P-value:2.03E-4 ID:SGTC_1049|Compound:3226-0134|FD-Score:2.92|P-value:9.55E-4 ID:SGTC_1120|Compound:ficusin|FD-Score:3.50|P-value:9.96E-5 ID:SGTC_1205|Compound:4161-2785|FD-Score:4.03|P-value:9.44E-6 ID:SGTC_1214|Compound:0358-0031|FD-Score:4.09|P-value:6.98E-6 ID:SGTC_1278|Compound:0874-0585|FD-Score:3.49|P-value:1.08E-4 ID:SGTC_1295|Compound:1013-0063|FD-Score:3.08|P-value:5.43E-4 ID:SGTC_1385|Compound:3091-4834|FD-Score:2.92|P-value:9.50E-4 ID:SGTC_1429|Compound:4049-0205|FD-Score:2.98|P-value:7.80E-4 ID:SGTC_1457|Compound:k015-0032|FD-Score:-3.30|P-value:2.45E-4 ID:SGTC_1501|Compound:4491-0275|FD-Score:3.75|P-value:3.40E-5 ID:SGTC_1733|Compound:st037357|FD-Score:6.89|P-value:1.39E-13 ID:SGTC_1747|Compound:st037496|FD-Score:3.79|P-value:2.88E-5 ID:SGTC_1758|Compound:st042942|FD-Score:2.94|P-value:8.99E-4 ID:SGTC_1865|Compound:st057639|FD-Score:3.18|P-value:3.61E-4 ID:SGTC_1875|Compound:nocodazole|FD-Score:3.51|P-value:9.91E-5 ID:SGTC_1885|Compound:st057546|FD-Score:3.34|P-value:1.94E-4 ID:SGTC_1915|Compound:st067105|FD-Score:-3.30|P-value:2.45E-4 ID:SGTC_1929|Compound:genistein trimethyl ether|FD-Score:3.88|P-value:1.90E-5 ID:SGTC_2087|Compound:5276107|FD-Score:3.22|P-value:3.11E-4 ID:SGTC_2139|Compound:5578692|FD-Score:5.64|P-value:1.14E-9 ID:SGTC_2148|Compound:5546263|FD-Score:3.20|P-value:3.34E-4 ID:SGTC_2329|Compound:6138490|FD-Score:4.35|P-value:1.98E-6 ID:SGTC_2342|Compound:7990637|FD-Score:3.68|P-value:4.61E-5 ID:SGTC_2357|Compound:9067248|FD-Score:-4.76|P-value:2.52E-7 ID:SGTC_2408|Compound:sulbentine|FD-Score:-3.01|P-value:7.40E-4 ID:SGTC_2589|Compound:lobaric acid|FD-Score:-3.34|P-value:2.10E-4 ID:SGTC_2635|Compound:hydroquinidine|FD-Score:2.92|P-value:9.75E-4 ID:SGTC_2665|Compound:lovastatin|FD-Score:-3.09|P-value:5.58E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:3.21|P-value:3.28E-4 ID:SGTC_2720|Compound:fluspirilene|FD-Score:3.07|P-value:5.62E-4 ID:SGTC_2759|Compound:disulfiram|FD-Score:3.82|P-value:2.47E-5 ID:SGTC_2827|Compound:7993847|FD-Score:4.72|P-value:2.81E-7 ID:SGTC_2845|Compound:9003024|FD-Score:3.20|P-value:3.45E-4 ID:SGTC_2864|Compound:9034755|FD-Score:3.26|P-value:2.73E-4 ID:SGTC_2941|Compound:9056145|FD-Score:4.99|P-value:6.01E-8 ID:SGTC_3065|Compound:9113888|FD-Score:6.18|P-value:2.77E-11 ID:SGTC_3066|Compound:9117245|FD-Score:-3.25|P-value:3.04E-4 ID:SGTC_3179|Compound:9107801|FD-Score:-3.02|P-value:7.32E-4 ID:SGTC_3205|Compound:9113483|FD-Score:3.61|P-value:6.45E-5 ID:SGTC_3222|Compound:9128301|FD-Score:3.21|P-value:3.22E-4 ID:SGTC_3253|Compound:9135987|FD-Score:3.36|P-value:1.83E-4 ID:SGTC_3308|Compound:9128332|FD-Score:3.20|P-value:3.41E-4 ID:SGTC_102|Compound:gallobenzophenone|FD-Score:3.55|P-value:8.14E-5 ID:SGTC_130|Compound:0136-0219|FD-Score:3.16|P-value:3.93E-4 ID:SGTC_164|Compound:4100-3994|FD-Score:3.05|P-value:6.01E-4 ID:SGTC_389|Compound:tpck|FD-Score:3.95|P-value:1.41E-5 ID:SGTC_864|Compound:0469-0573|FD-Score:3.33|P-value:2.03E-4 ID:SGTC_1049|Compound:3226-0134|FD-Score:2.92|P-value:9.55E-4 ID:SGTC_1120|Compound:ficusin|FD-Score:3.50|P-value:9.96E-5 ID:SGTC_1205|Compound:4161-2785|FD-Score:4.03|P-value:9.44E-6 ID:SGTC_1214|Compound:0358-0031|FD-Score:4.09|P-value:6.98E-6 ID:SGTC_1278|Compound:0874-0585|FD-Score:3.49|P-value:1.08E-4 ID:SGTC_1295|Compound:1013-0063|FD-Score:3.08|P-value:5.43E-4 ID:SGTC_1385|Compound:3091-4834|FD-Score:2.92|P-value:9.50E-4 ID:SGTC_1429|Compound:4049-0205|FD-Score:2.98|P-value:7.80E-4 ID:SGTC_1457|Compound:k015-0032|FD-Score:-3.30|P-value:2.45E-4 ID:SGTC_1501|Compound:4491-0275|FD-Score:3.75|P-value:3.40E-5 ID:SGTC_1733|Compound:st037357|FD-Score:6.89|P-value:1.39E-13 ID:SGTC_1747|Compound:st037496|FD-Score:3.79|P-value:2.88E-5 ID:SGTC_1758|Compound:st042942|FD-Score:2.94|P-value:8.99E-4 ID:SGTC_1865|Compound:st057639|FD-Score:3.18|P-value:3.61E-4 ID:SGTC_1875|Compound:nocodazole|FD-Score:3.51|P-value:9.91E-5 ID:SGTC_1885|Compound:st057546|FD-Score:3.34|P-value:1.94E-4 ID:SGTC_1915|Compound:st067105|FD-Score:-3.30|P-value:2.45E-4 ID:SGTC_1929|Compound:genistein trimethyl ether|FD-Score:3.88|P-value:1.90E-5 ID:SGTC_2087|Compound:5276107|FD-Score:3.22|P-value:3.11E-4 ID:SGTC_2139|Compound:5578692|FD-Score:5.64|P-value:1.14E-9 ID:SGTC_2148|Compound:5546263|FD-Score:3.20|P-value:3.34E-4 ID:SGTC_2329|Compound:6138490|FD-Score:4.35|P-value:1.98E-6 ID:SGTC_2342|Compound:7990637|FD-Score:3.68|P-value:4.61E-5 ID:SGTC_2357|Compound:9067248|FD-Score:-4.76|P-value:2.52E-7 ID:SGTC_2408|Compound:sulbentine|FD-Score:-3.01|P-value:7.40E-4 ID:SGTC_2589|Compound:lobaric acid|FD-Score:-3.34|P-value:2.10E-4 ID:SGTC_2635|Compound:hydroquinidine|FD-Score:2.92|P-value:9.75E-4 ID:SGTC_2665|Compound:lovastatin|FD-Score:-3.09|P-value:5.58E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:3.21|P-value:3.28E-4 ID:SGTC_2720|Compound:fluspirilene|FD-Score:3.07|P-value:5.62E-4 ID:SGTC_2759|Compound:disulfiram|FD-Score:3.82|P-value:2.47E-5 ID:SGTC_2827|Compound:7993847|FD-Score:4.72|P-value:2.81E-7 ID:SGTC_2845|Compound:9003024|FD-Score:3.20|P-value:3.45E-4 ID:SGTC_2864|Compound:9034755|FD-Score:3.26|P-value:2.73E-4 ID:SGTC_2941|Compound:9056145|FD-Score:4.99|P-value:6.01E-8 ID:SGTC_3065|Compound:9113888|FD-Score:6.18|P-value:2.77E-11 ID:SGTC_3066|Compound:9117245|FD-Score:-3.25|P-value:3.04E-4 ID:SGTC_3179|Compound:9107801|FD-Score:-3.02|P-value:7.32E-4 ID:SGTC_3205|Compound:9113483|FD-Score:3.61|P-value:6.45E-5 ID:SGTC_3222|Compound:9128301|FD-Score:3.21|P-value:3.22E-4 ID:SGTC_3253|Compound:9135987|FD-Score:3.36|P-value:1.83E-4 ID:SGTC_3308|Compound:9128332|FD-Score:3.20|P-value:3.41E-4

Top fitness defect scores for YGR210C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1733 st037357 6.89 54.9 µM 1.39E-13 60S ribosome export 2 2.76E-12
2 SGTC_3065 9113888 6.18 49.5 µM 2.77E-11 4 3.13E-10
3 SGTC_2139 5578692 5.64 56.5 µM 1.14E-9 superoxide 5 8.66E-9
4 SGTC_2941 9056145 4.99 11.2 µM 6.01E-8 7 3.00E-7
5 SGTC_2827 7993847 4.72 71.4 µM 2.81E-7 12 1.19E-6
6 SGTC_2329 6138490 4.35 200.0 µM 1.98E-6 19 6.86E-6
7 SGTC_1214 0358-0031 4.09 63.7 µM 6.98E-6 12 2.11E-5
8 SGTC_1205 4161-2785 4.03 76.0 µM 9.44E-6 27 2.77E-5
9 SGTC_389 tpck 3.95 16.7 µM 1.41E-5 29 3.96E-5
10 SGTC_1929 genistein trimethyl ether 3.88 50.5 µM 1.90E-5 15 5.17E-5
11 SGTC_2759 disulfiram 3.82 3.4 µM 2.47E-5 40 6.56E-5
12 SGTC_1747 st037496 3.79 66.6 µM 2.88E-5 20 7.51E-5
13 SGTC_1501 4491-0275 3.75 38.4 µM 3.40E-5 13 8.73E-5
14 SGTC_2342 7990637 3.68 118.9 µM 4.61E-5 RNA processing & uracil transport 46 1.15E-4
15 SGTC_3205 9113483 3.61 49.5 µM 6.45E-5 43 1.55E-4
16 SGTC_102 gallobenzophenone 3.55 83.6 µM 8.14E-5 redox potentiating 54 1.91E-4
17 SGTC_1875 nocodazole 3.51 6.0 µM 9.91E-5 tubulin folding & SWR complex 59 2.28E-4
18 SGTC_1120 ficusin 3.50 1.8 µM 9.96E-5 40 2.29E-4
19 SGTC_1278 0874-0585 3.49 172.0 µM 1.08E-4 24 2.46E-4
20 SGTC_3253 9135987 3.36 49.5 µM 1.83E-4 60S ribosome export 26 3.94E-4

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.116 1.33E-11 YGL094C PAN2 hom Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes
0.102 2.73E-9 YKL014C URB1 het Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit
0.102 2.94E-9 YML068W ITT1 hom Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins
0.102 3.60E-9 YGR242W_d YGR242W_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
0.101 4.37E-9 YLR285W NNT1 hom S-adenosylmethionine-dependent methyltransferase; has a role in rDNA silencing and in lifespan determination
0.082 2.07E-6 YPL267W ACM1 hom Pseudosubstrate inhibitor of the anaphase-promoting complex/cyclosome (APC/C), that suppresses APC/C [Cdh1]-mediated proteolysis of mitotic cyclins; associates with Cdh1p, Bmh1p and Bmh2p; cell cycle regulated protein
0.080 3.13E-6 YEL063C CAN1 hom Plasma membrane arginine permease; requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance; CAN1 has a paralog, ALP1, that arose from the whole genome duplication
0.079 4.78E-6 YMR119W-A_d YMR119W-A_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.079 5.48E-6 YLR327C TMA10 hom Protein of unknown function that associates with ribosomes; putative homolog of the F1F0-ATPase synthase regulator Stf2p; protein abundance increases in response to DNA replication stress
0.078 5.74E-6 YMR113W FOL3 het Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis
0.078 5.81E-6 YER013W PRP22 het DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
0.077 7.32E-6 YBL040C ERD2 het HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins
0.077 7.94E-6 YER062C HOR2 hom Glycerol-1-phosphatase involved in glycerol biosynthesis; induced in response to hyperosmotic or oxidative stress, and during diauxic shift; HOR2 has a paralog, RHR2, that arose from the whole genome duplication
0.076 9.50E-6 YIL141W_d YIL141W_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.076 9.69E-6 YJL008C CCT8 het Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo