YHR030C / SLT2

Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to the phagophore assembly site (PAS); regulated by the PKC1-mediated signaling pathway

Zygosity: Homozygous strain
fixedexpanded
Profile for YHR030C / SLT2

Click on Significant Values for Screen Details ID:SGTC_22|Compound:0964-0034|FD-Score:5.70|P-value:3.95E-5 ID:SGTC_64|Compound:000l-0018|FD-Score:11.60|P-value:4.01E-16 ID:SGTC_71|Compound:0417-1750|FD-Score:18.60|P-value:1.71E-38 ID:SGTC_77|Compound:0828-0286|FD-Score:5.37|P-value:1.01E-4 ID:SGTC_86|Compound:0417-1630|FD-Score:14.40|P-value:9.84E-24 ID:SGTC_91|Compound:0417-1751|FD-Score:10.40|P-value:2.06E-13 ID:SGTC_108|Compound:0509-0257|FD-Score:7.68|P-value:5.15E-8 ID:SGTC_109|Compound:0132-0036|FD-Score:7.62|P-value:6.35E-8 ID:SGTC_110|Compound:0850-0284|FD-Score:4.58|P-value:7.85E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:-10.20|P-value:6.05E-13 ID:SGTC_123|Compound:0083-0120|FD-Score:-7.26|P-value:1.84E-7 ID:SGTC_129|Compound:0088-0017|FD-Score:9.44|P-value:2.88E-11 ID:SGTC_137|Compound:0438-0332|FD-Score:19.80|P-value:2.44E-43 ID:SGTC_138|Compound:0850-0259|FD-Score:18.90|P-value:7.86E-40 ID:SGTC_142|Compound:0335-0849|FD-Score:17.60|P-value:1.16E-34 ID:SGTC_158|Compound:k038-0087|FD-Score:4.61|P-value:7.27E-4 ID:SGTC_159|Compound:3970-0959|FD-Score:-6.69|P-value:1.40E-6 ID:SGTC_161|Compound:4065-0411|FD-Score:7.97|P-value:1.62E-8 ID:SGTC_163|Compound:1327-0036|FD-Score:6.26|P-value:7.38E-6 ID:SGTC_165|Compound:k038-0023|FD-Score:6.47|P-value:3.69E-6 ID:SGTC_173|Compound:1273-0061|FD-Score:13.20|P-value:2.10E-20 ID:SGTC_181|Compound:1447-1644|FD-Score:15.70|P-value:7.63E-28 ID:SGTC_188|Compound:3229-0966|FD-Score:-4.71|P-value:4.79E-4 ID:SGTC_238|Compound:5hr heat shock (37°C) + nsc-638432|FD-Score:8.96|P-value:2.58E-10 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:5.40|P-value:9.33E-5 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:9.96|P-value:2.43E-12 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:21.60|P-value:1.96E-51 ID:SGTC_242|Compound:5hr heat shock (37°C) + 5-fluorouracil|FD-Score:9.10|P-value:1.38E-10 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:7.27|P-value:2.36E-7 ID:SGTC_252|Compound:miconazole|FD-Score:6.02|P-value:1.56E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:5.35|P-value:1.08E-4 ID:SGTC_255|Compound:tunicamycin|FD-Score:11.60|P-value:3.10E-16 ID:SGTC_294|Compound:k038-0071|FD-Score:8.13|P-value:8.65E-9 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.06|P-value:1.94E-4 ID:SGTC_313|Compound:3474-0040|FD-Score:5.82|P-value:2.83E-5 ID:SGTC_332|Compound:4112-0506|FD-Score:4.50|P-value:9.38E-4 ID:SGTC_340|Compound:k038-0059|FD-Score:9.89|P-value:3.36E-12 ID:SGTC_351|Compound:caspofungin|FD-Score:9.52|P-value:1.96E-11 ID:SGTC_353|Compound:1988-1175|FD-Score:6.68|P-value:1.88E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:9.83|P-value:4.47E-12 ID:SGTC_360|Compound:0957-0399|FD-Score:24.60|P-value:5.28E-66 ID:SGTC_367|Compound:0335-0881|FD-Score:20.30|P-value:1.10E-45 ID:SGTC_369|Compound:0957-0393|FD-Score:25.50|P-value:1.24E-70 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:4.97|P-value:2.96E-4 ID:SGTC_408|Compound:cantharidin|FD-Score:16.70|P-value:1.41E-31 ID:SGTC_422|Compound:cantharidin|FD-Score:27.80|P-value:1.84E-83 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-10.10|P-value:9.46E-13 ID:SGTC_459|Compound:nigericin|FD-Score:5.69|P-value:4.11E-5 ID:SGTC_469|Compound:w7|FD-Score:4.58|P-value:7.82E-4 ID:SGTC_483|Compound:fpl-64176|FD-Score:8.14|P-value:8.37E-9 ID:SGTC_497|Compound:capsazepine|FD-Score:-4.73|P-value:4.56E-4 ID:SGTC_500|Compound:h-89|FD-Score:28.10|P-value:3.83E-85 ID:SGTC_509|Compound:pifithrin|FD-Score:6.57|P-value:2.68E-6 ID:SGTC_514|Compound:4466-0038|FD-Score:7.99|P-value:1.53E-8 ID:SGTC_531|Compound:3788-1495|FD-Score:12.00|P-value:3.06E-17 ID:SGTC_542|Compound:3381-0244|FD-Score:7.03|P-value:5.55E-7 ID:SGTC_562|Compound:3772-2733|FD-Score:7.24|P-value:2.66E-7 ID:SGTC_574|Compound:1315-0397|FD-Score:9.32|P-value:4.97E-11 ID:SGTC_577|Compound:r071-0003|FD-Score:5.31|P-value:1.20E-4 ID:SGTC_582|Compound:0987-0078|FD-Score:6.18|P-value:9.36E-6 ID:SGTC_586|Compound:0957-0265|FD-Score:12.70|P-value:7.75E-19 ID:SGTC_635|Compound:k038-0028|FD-Score:11.50|P-value:5.68E-16 ID:SGTC_637|Compound:1181-0519|FD-Score:15.00|P-value:1.40E-25 ID:SGTC_642|Compound:0335-0876|FD-Score:17.50|P-value:1.70E-34 ID:SGTC_646|Compound:4092-0839|FD-Score:6.39|P-value:4.76E-6 ID:SGTC_649|Compound:1123-0311|FD-Score:12.60|P-value:1.09E-18 ID:SGTC_663|Compound:1486-0733|FD-Score:38.60|P-value:6.35E-159 ID:SGTC_664|Compound:1222-0054|FD-Score:4.89|P-value:3.62E-4 ID:SGTC_666|Compound:0272-0154|FD-Score:12.00|P-value:3.99E-17 ID:SGTC_669|Compound:0108-0021|FD-Score:5.85|P-value:2.60E-5 ID:SGTC_689|Compound:0833-0039|FD-Score:7.76|P-value:3.78E-8 ID:SGTC_710|Compound:3448-4187|FD-Score:9.18|P-value:9.45E-11 ID:SGTC_721|Compound:1187-1332|FD-Score:8.42|P-value:2.67E-9 ID:SGTC_743|Compound:1275-0778|FD-Score:9.16|P-value:1.06E-10 ID:SGTC_750|Compound:4073-0104|FD-Score:5.17|P-value:1.73E-4 ID:SGTC_759|Compound:3486-0358|FD-Score:6.00|P-value:1.63E-5 ID:SGTC_764|Compound:1951-2361|FD-Score:4.54|P-value:8.62E-4 ID:SGTC_768|Compound:0384-0033|FD-Score:5.60|P-value:5.31E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:10.00|P-value:1.72E-12 ID:SGTC_807|Compound:1315-0151|FD-Score:5.48|P-value:7.53E-5 ID:SGTC_825|Compound:1988-2224|FD-Score:11.40|P-value:1.34E-15 ID:SGTC_837|Compound:0091-0265|FD-Score:10.10|P-value:1.39E-12 ID:SGTC_839|Compound:0122-0028|FD-Score:5.83|P-value:2.75E-5 ID:SGTC_846|Compound:0335-0850|FD-Score:9.77|P-value:6.06E-12 ID:SGTC_852|Compound:0418-0143|FD-Score:12.40|P-value:4.22E-18 ID:SGTC_863|Compound:0466-0191|FD-Score:10.30|P-value:3.46E-13 ID:SGTC_875|Compound:0709-0210|FD-Score:5.60|P-value:5.27E-5 ID:SGTC_878|Compound:0828-0289|FD-Score:7.36|P-value:1.71E-7 ID:SGTC_883|Compound:0850-0245|FD-Score:10.20|P-value:6.20E-13 ID:SGTC_887|Compound:0885-0007|FD-Score:10.60|P-value:1.19E-13 ID:SGTC_905|Compound:2-aminofluorene|FD-Score:18.70|P-value:4.35E-39 ID:SGTC_916|Compound:4466-0038|FD-Score:5.12|P-value:2.01E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:5.85|P-value:2.60E-5 ID:SGTC_964|Compound:1287-0107|FD-Score:15.50|P-value:1.64E-27 ID:SGTC_971|Compound:1315-0384|FD-Score:5.07|P-value:2.29E-4 ID:SGTC_994|Compound:3910-0338|FD-Score:5.15|P-value:1.87E-4 ID:SGTC_1007|Compound:4101-0031|FD-Score:4.69|P-value:5.97E-4 ID:SGTC_1063|Compound:disulfiram|FD-Score:5.78|P-value:3.13E-5 ID:SGTC_1070|Compound:indatraline|FD-Score:9.43|P-value:3.05E-11 ID:SGTC_1072|Compound:oxiconazole|FD-Score:7.85|P-value:2.66E-8 ID:SGTC_1081|Compound:sertraline|FD-Score:16.80|P-value:1.00E-31 ID:SGTC_1088|Compound:bifonazole|FD-Score:5.71|P-value:3.87E-5 ID:SGTC_1103|Compound:duloxetine|FD-Score:5.75|P-value:3.43E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:6.97|P-value:6.91E-7 ID:SGTC_1172|Compound:0370-0043|FD-Score:-4.88|P-value:3.08E-4 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.95|P-value:3.10E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:5.61|P-value:5.21E-5 ID:SGTC_1268|Compound:0828-0275|FD-Score:4.77|P-value:4.92E-4 ID:SGTC_1272|Compound:0839-0021|FD-Score:7.15|P-value:3.68E-7 ID:SGTC_1273|Compound:0849-0096|FD-Score:-4.53|P-value:7.32E-4 ID:SGTC_1318|Compound:1280-3875|FD-Score:5.27|P-value:1.34E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:7.77|P-value:3.63E-8 ID:SGTC_1423|Compound:4048-0112|FD-Score:6.34|P-value:5.62E-6 ID:SGTC_1427|Compound:4048-4900|FD-Score:8.66|P-value:9.60E-10 ID:SGTC_1469|Compound:k284-2957|FD-Score:5.03|P-value:2.54E-4 ID:SGTC_1482|Compound:3346-2049|FD-Score:8.82|P-value:4.71E-10 ID:SGTC_1547|Compound:harmine|FD-Score:15.00|P-value:9.78E-26 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:6.27|P-value:7.12E-6 ID:SGTC_1614|Compound:st002383|FD-Score:19.20|P-value:5.21E-41 ID:SGTC_1644|Compound:st010134|FD-Score:5.37|P-value:1.02E-4 ID:SGTC_1649|Compound:st011737|FD-Score:9.07|P-value:1.60E-10 ID:SGTC_1656|Compound:st012921|FD-Score:4.56|P-value:8.13E-4 ID:SGTC_1672|Compound:st016598|FD-Score:14.30|P-value:1.82E-23 ID:SGTC_1679|Compound:4130-1276|FD-Score:9.99|P-value:2.09E-12 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:9.50|P-value:2.23E-11 ID:SGTC_1736|Compound:st036774|FD-Score:4.84|P-value:4.07E-4 ID:SGTC_1787|Compound:fluconazole|FD-Score:-5.37|P-value:8.30E-5 ID:SGTC_1789|Compound:tunicamycin|FD-Score:6.33|P-value:5.88E-6 ID:SGTC_1797|Compound:st048695|FD-Score:4.68|P-value:6.14E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.10|P-value:1.20E-5 ID:SGTC_1874|Compound:staurosporine|FD-Score:15.60|P-value:1.36E-27 ID:SGTC_1877|Compound:wortmannin|FD-Score:6.93|P-value:7.89E-7 ID:SGTC_1907|Compound:st060210|FD-Score:12.00|P-value:4.83E-17 ID:SGTC_1933|Compound:st074711|FD-Score:8.63|P-value:1.08E-9 ID:SGTC_1959|Compound:st077091|FD-Score:6.01|P-value:1.57E-5 ID:SGTC_1982|Compound:st072467|FD-Score:4.48|P-value:9.80E-4 ID:SGTC_2003|Compound:4023581|FD-Score:11.90|P-value:8.22E-17 ID:SGTC_2007|Compound:4011539|FD-Score:20.70|P-value:4.31E-47 ID:SGTC_2009|Compound:4012297|FD-Score:19.10|P-value:1.38E-40 ID:SGTC_2016|Compound:5121758|FD-Score:7.12|P-value:3.98E-7 ID:SGTC_2028|Compound:5153890|FD-Score:17.90|P-value:5.45E-36 ID:SGTC_2036|Compound:5160441|FD-Score:7.45|P-value:1.20E-7 ID:SGTC_2049|Compound:5262831|FD-Score:7.22|P-value:2.86E-7 ID:SGTC_2050|Compound:5263056|FD-Score:10.50|P-value:1.79E-13 ID:SGTC_2057|Compound:5236571|FD-Score:6.23|P-value:7.95E-6 ID:SGTC_2132|Compound:5317594|FD-Score:6.17|P-value:9.59E-6 ID:SGTC_2149|Compound:5554786|FD-Score:17.60|P-value:1.60E-34 ID:SGTC_2210|Compound:7115885|FD-Score:20.50|P-value:2.45E-46 ID:SGTC_2241|Compound:6772625|FD-Score:5.03|P-value:2.51E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:6.36|P-value:5.29E-6 ID:SGTC_2254|Compound:7938975|FD-Score:5.81|P-value:2.88E-5 ID:SGTC_2257|Compound:7960413|FD-Score:5.85|P-value:2.55E-5 ID:SGTC_2272|Compound:7805186|FD-Score:18.10|P-value:1.32E-36 ID:SGTC_2286|Compound:7945697|FD-Score:12.70|P-value:4.98E-19 ID:SGTC_2289|Compound:7946404|FD-Score:7.45|P-value:1.21E-7 ID:SGTC_2300|Compound:7976697|FD-Score:11.20|P-value:4.62E-15 ID:SGTC_2384|Compound:9036245|FD-Score:5.42|P-value:8.89E-5 ID:SGTC_2399|Compound:5884133|FD-Score:12.60|P-value:8.13E-19 ID:SGTC_2430|Compound:5571206|FD-Score:7.39|P-value:1.51E-7 ID:SGTC_2488|Compound:5268135|FD-Score:4.84|P-value:4.13E-4 ID:SGTC_2489|Compound:cantharidin|FD-Score:17.30|P-value:1.71E-33 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:4.47|P-value:9.98E-4 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:11.30|P-value:2.14E-15 ID:SGTC_2581|Compound:avocatin a|FD-Score:6.35|P-value:5.40E-6 ID:SGTC_2584|Compound:androsterone|FD-Score:7.17|P-value:3.39E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:6.71|P-value:1.65E-6 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:5.22|P-value:1.54E-4 ID:SGTC_2619|Compound:obliquin|FD-Score:18.40|P-value:1.44E-37 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:6.75|P-value:1.47E-6 ID:SGTC_2648|Compound:atorvastatin|FD-Score:6.23|P-value:8.10E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.86|P-value:3.94E-10 ID:SGTC_2694|Compound:st077685|FD-Score:5.36|P-value:1.05E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:5.77|P-value:3.23E-5 ID:SGTC_2713|Compound:st079149|FD-Score:7.18|P-value:3.27E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:10.60|P-value:8.18E-14 ID:SGTC_2772|Compound:vinpocetine|FD-Score:4.91|P-value:3.47E-4 ID:SGTC_2776|Compound:terbinafine|FD-Score:35.30|P-value:1.78E-133 ID:SGTC_2777|Compound:climbazole|FD-Score:5.68|P-value:4.22E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:8.07|P-value:1.10E-8 ID:SGTC_2816|Compound:7982706|FD-Score:10.00|P-value:1.94E-12 ID:SGTC_2890|Compound:9046729|FD-Score:15.20|P-value:2.47E-26 ID:SGTC_2896|Compound:9052656|FD-Score:13.70|P-value:6.70E-22 ID:SGTC_2912|Compound:7964298|FD-Score:32.70|P-value:4.37E-115 ID:SGTC_2924|Compound:9010168|FD-Score:26.80|P-value:1.43E-77 ID:SGTC_2929|Compound:9013348|FD-Score:5.59|P-value:5.49E-5 ID:SGTC_2980|Compound:9014342|FD-Score:-4.76|P-value:4.21E-4 ID:SGTC_2997|Compound:9067075|FD-Score:16.20|P-value:1.05E-29 ID:SGTC_3006|Compound:9075424|FD-Score:7.82|P-value:2.98E-8 ID:SGTC_3007|Compound:9078383|FD-Score:4.89|P-value:3.62E-4 ID:SGTC_3016|Compound:9080866|FD-Score:-5.73|P-value:2.98E-5 ID:SGTC_3018|Compound:9082602|FD-Score:15.70|P-value:3.82E-28 ID:SGTC_3055|Compound:9094636|FD-Score:-5.28|P-value:1.07E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:16.40|P-value:1.51E-30 ID:SGTC_3060|Compound:1327-0027|FD-Score:14.30|P-value:1.20E-23 ID:SGTC_3063|Compound:1327-0034|FD-Score:18.10|P-value:1.68E-36 ID:SGTC_3064|Compound:1327-0027|FD-Score:7.85|P-value:2.68E-8 ID:SGTC_3078|Compound:9116413|FD-Score:9.45|P-value:2.73E-11 ID:SGTC_3092|Compound:9117248|FD-Score:6.20|P-value:8.95E-6 ID:SGTC_3099|Compound:9120367|FD-Score:4.49|P-value:9.67E-4 ID:SGTC_3122|Compound:9126309|FD-Score:8.75|P-value:6.37E-10 ID:SGTC_3129|Compound:9127257|FD-Score:-4.63|P-value:5.71E-4 ID:SGTC_3152|Compound:9099253|FD-Score:12.60|P-value:1.16E-18 ID:SGTC_3154|Compound:9100113|FD-Score:5.25|P-value:1.42E-4 ID:SGTC_3266|Compound:9136860|FD-Score:9.67|P-value:9.97E-12 ID:SGTC_3277|Compound:9138724|FD-Score:4.53|P-value:8.75E-4 ID:SGTC_3285|Compound:9112818|FD-Score:6.57|P-value:2.64E-6 ID:SGTC_3310|Compound:9130229|FD-Score:7.38|P-value:1.55E-7 ID:SGTC_3311|Compound:9131146|FD-Score:9.55|P-value:1.69E-11 ID:SGTC_3321|Compound:9137793|FD-Score:4.86|P-value:3.87E-4 ID:SGTC_3331|Compound:9141060|FD-Score:6.62|P-value:2.28E-6 ID:SGTC_3336|Compound:9143619|FD-Score:8.06|P-value:1.14E-8 ID:SGTC_3338|Compound:9144300|FD-Score:7.02|P-value:5.81E-7 ID:SGTC_3347|Compound:9188721|FD-Score:4.99|P-value:2.79E-4 ID:SGTC_3350|Compound:9150499|FD-Score:14.80|P-value:4.64E-25 ID:SGTC_3351|Compound:9150312|FD-Score:5.05|P-value:2.41E-4 ID:SGTC_3356|Compound:9151811|FD-Score:6.79|P-value:1.26E-6 ID:SGTC_22|Compound:0964-0034|FD-Score:5.70|P-value:3.95E-5 ID:SGTC_64|Compound:000l-0018|FD-Score:11.60|P-value:4.01E-16 ID:SGTC_71|Compound:0417-1750|FD-Score:18.60|P-value:1.71E-38 ID:SGTC_77|Compound:0828-0286|FD-Score:5.37|P-value:1.01E-4 ID:SGTC_86|Compound:0417-1630|FD-Score:14.40|P-value:9.84E-24 ID:SGTC_91|Compound:0417-1751|FD-Score:10.40|P-value:2.06E-13 ID:SGTC_108|Compound:0509-0257|FD-Score:7.68|P-value:5.15E-8 ID:SGTC_109|Compound:0132-0036|FD-Score:7.62|P-value:6.35E-8 ID:SGTC_110|Compound:0850-0284|FD-Score:4.58|P-value:7.85E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:-10.20|P-value:6.05E-13 ID:SGTC_123|Compound:0083-0120|FD-Score:-7.26|P-value:1.84E-7 ID:SGTC_129|Compound:0088-0017|FD-Score:9.44|P-value:2.88E-11 ID:SGTC_137|Compound:0438-0332|FD-Score:19.80|P-value:2.44E-43 ID:SGTC_138|Compound:0850-0259|FD-Score:18.90|P-value:7.86E-40 ID:SGTC_142|Compound:0335-0849|FD-Score:17.60|P-value:1.16E-34 ID:SGTC_158|Compound:k038-0087|FD-Score:4.61|P-value:7.27E-4 ID:SGTC_159|Compound:3970-0959|FD-Score:-6.69|P-value:1.40E-6 ID:SGTC_161|Compound:4065-0411|FD-Score:7.97|P-value:1.62E-8 ID:SGTC_163|Compound:1327-0036|FD-Score:6.26|P-value:7.38E-6 ID:SGTC_165|Compound:k038-0023|FD-Score:6.47|P-value:3.69E-6 ID:SGTC_173|Compound:1273-0061|FD-Score:13.20|P-value:2.10E-20 ID:SGTC_181|Compound:1447-1644|FD-Score:15.70|P-value:7.63E-28 ID:SGTC_188|Compound:3229-0966|FD-Score:-4.71|P-value:4.79E-4 ID:SGTC_238|Compound:5hr heat shock (37°C) + nsc-638432|FD-Score:8.96|P-value:2.58E-10 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:5.40|P-value:9.33E-5 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:9.96|P-value:2.43E-12 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:21.60|P-value:1.96E-51 ID:SGTC_242|Compound:5hr heat shock (37°C) + 5-fluorouracil|FD-Score:9.10|P-value:1.38E-10 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:7.27|P-value:2.36E-7 ID:SGTC_252|Compound:miconazole|FD-Score:6.02|P-value:1.56E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:5.35|P-value:1.08E-4 ID:SGTC_255|Compound:tunicamycin|FD-Score:11.60|P-value:3.10E-16 ID:SGTC_294|Compound:k038-0071|FD-Score:8.13|P-value:8.65E-9 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.06|P-value:1.94E-4 ID:SGTC_313|Compound:3474-0040|FD-Score:5.82|P-value:2.83E-5 ID:SGTC_332|Compound:4112-0506|FD-Score:4.50|P-value:9.38E-4 ID:SGTC_340|Compound:k038-0059|FD-Score:9.89|P-value:3.36E-12 ID:SGTC_351|Compound:caspofungin|FD-Score:9.52|P-value:1.96E-11 ID:SGTC_353|Compound:1988-1175|FD-Score:6.68|P-value:1.88E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:9.83|P-value:4.47E-12 ID:SGTC_360|Compound:0957-0399|FD-Score:24.60|P-value:5.28E-66 ID:SGTC_367|Compound:0335-0881|FD-Score:20.30|P-value:1.10E-45 ID:SGTC_369|Compound:0957-0393|FD-Score:25.50|P-value:1.24E-70 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:4.97|P-value:2.96E-4 ID:SGTC_408|Compound:cantharidin|FD-Score:16.70|P-value:1.41E-31 ID:SGTC_422|Compound:cantharidin|FD-Score:27.80|P-value:1.84E-83 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-10.10|P-value:9.46E-13 ID:SGTC_459|Compound:nigericin|FD-Score:5.69|P-value:4.11E-5 ID:SGTC_469|Compound:w7|FD-Score:4.58|P-value:7.82E-4 ID:SGTC_483|Compound:fpl-64176|FD-Score:8.14|P-value:8.37E-9 ID:SGTC_497|Compound:capsazepine|FD-Score:-4.73|P-value:4.56E-4 ID:SGTC_500|Compound:h-89|FD-Score:28.10|P-value:3.83E-85 ID:SGTC_509|Compound:pifithrin|FD-Score:6.57|P-value:2.68E-6 ID:SGTC_514|Compound:4466-0038|FD-Score:7.99|P-value:1.53E-8 ID:SGTC_531|Compound:3788-1495|FD-Score:12.00|P-value:3.06E-17 ID:SGTC_542|Compound:3381-0244|FD-Score:7.03|P-value:5.55E-7 ID:SGTC_562|Compound:3772-2733|FD-Score:7.24|P-value:2.66E-7 ID:SGTC_574|Compound:1315-0397|FD-Score:9.32|P-value:4.97E-11 ID:SGTC_577|Compound:r071-0003|FD-Score:5.31|P-value:1.20E-4 ID:SGTC_582|Compound:0987-0078|FD-Score:6.18|P-value:9.36E-6 ID:SGTC_586|Compound:0957-0265|FD-Score:12.70|P-value:7.75E-19 ID:SGTC_635|Compound:k038-0028|FD-Score:11.50|P-value:5.68E-16 ID:SGTC_637|Compound:1181-0519|FD-Score:15.00|P-value:1.40E-25 ID:SGTC_642|Compound:0335-0876|FD-Score:17.50|P-value:1.70E-34 ID:SGTC_646|Compound:4092-0839|FD-Score:6.39|P-value:4.76E-6 ID:SGTC_649|Compound:1123-0311|FD-Score:12.60|P-value:1.09E-18 ID:SGTC_663|Compound:1486-0733|FD-Score:38.60|P-value:6.35E-159 ID:SGTC_664|Compound:1222-0054|FD-Score:4.89|P-value:3.62E-4 ID:SGTC_666|Compound:0272-0154|FD-Score:12.00|P-value:3.99E-17 ID:SGTC_669|Compound:0108-0021|FD-Score:5.85|P-value:2.60E-5 ID:SGTC_689|Compound:0833-0039|FD-Score:7.76|P-value:3.78E-8 ID:SGTC_710|Compound:3448-4187|FD-Score:9.18|P-value:9.45E-11 ID:SGTC_721|Compound:1187-1332|FD-Score:8.42|P-value:2.67E-9 ID:SGTC_743|Compound:1275-0778|FD-Score:9.16|P-value:1.06E-10 ID:SGTC_750|Compound:4073-0104|FD-Score:5.17|P-value:1.73E-4 ID:SGTC_759|Compound:3486-0358|FD-Score:6.00|P-value:1.63E-5 ID:SGTC_764|Compound:1951-2361|FD-Score:4.54|P-value:8.62E-4 ID:SGTC_768|Compound:0384-0033|FD-Score:5.60|P-value:5.31E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:10.00|P-value:1.72E-12 ID:SGTC_807|Compound:1315-0151|FD-Score:5.48|P-value:7.53E-5 ID:SGTC_825|Compound:1988-2224|FD-Score:11.40|P-value:1.34E-15 ID:SGTC_837|Compound:0091-0265|FD-Score:10.10|P-value:1.39E-12 ID:SGTC_839|Compound:0122-0028|FD-Score:5.83|P-value:2.75E-5 ID:SGTC_846|Compound:0335-0850|FD-Score:9.77|P-value:6.06E-12 ID:SGTC_852|Compound:0418-0143|FD-Score:12.40|P-value:4.22E-18 ID:SGTC_863|Compound:0466-0191|FD-Score:10.30|P-value:3.46E-13 ID:SGTC_875|Compound:0709-0210|FD-Score:5.60|P-value:5.27E-5 ID:SGTC_878|Compound:0828-0289|FD-Score:7.36|P-value:1.71E-7 ID:SGTC_883|Compound:0850-0245|FD-Score:10.20|P-value:6.20E-13 ID:SGTC_887|Compound:0885-0007|FD-Score:10.60|P-value:1.19E-13 ID:SGTC_905|Compound:2-aminofluorene|FD-Score:18.70|P-value:4.35E-39 ID:SGTC_916|Compound:4466-0038|FD-Score:5.12|P-value:2.01E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:5.85|P-value:2.60E-5 ID:SGTC_964|Compound:1287-0107|FD-Score:15.50|P-value:1.64E-27 ID:SGTC_971|Compound:1315-0384|FD-Score:5.07|P-value:2.29E-4 ID:SGTC_994|Compound:3910-0338|FD-Score:5.15|P-value:1.87E-4 ID:SGTC_1007|Compound:4101-0031|FD-Score:4.69|P-value:5.97E-4 ID:SGTC_1063|Compound:disulfiram|FD-Score:5.78|P-value:3.13E-5 ID:SGTC_1070|Compound:indatraline|FD-Score:9.43|P-value:3.05E-11 ID:SGTC_1072|Compound:oxiconazole|FD-Score:7.85|P-value:2.66E-8 ID:SGTC_1081|Compound:sertraline|FD-Score:16.80|P-value:1.00E-31 ID:SGTC_1088|Compound:bifonazole|FD-Score:5.71|P-value:3.87E-5 ID:SGTC_1103|Compound:duloxetine|FD-Score:5.75|P-value:3.43E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:6.97|P-value:6.91E-7 ID:SGTC_1172|Compound:0370-0043|FD-Score:-4.88|P-value:3.08E-4 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.95|P-value:3.10E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:5.61|P-value:5.21E-5 ID:SGTC_1268|Compound:0828-0275|FD-Score:4.77|P-value:4.92E-4 ID:SGTC_1272|Compound:0839-0021|FD-Score:7.15|P-value:3.68E-7 ID:SGTC_1273|Compound:0849-0096|FD-Score:-4.53|P-value:7.32E-4 ID:SGTC_1318|Compound:1280-3875|FD-Score:5.27|P-value:1.34E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:7.77|P-value:3.63E-8 ID:SGTC_1423|Compound:4048-0112|FD-Score:6.34|P-value:5.62E-6 ID:SGTC_1427|Compound:4048-4900|FD-Score:8.66|P-value:9.60E-10 ID:SGTC_1469|Compound:k284-2957|FD-Score:5.03|P-value:2.54E-4 ID:SGTC_1482|Compound:3346-2049|FD-Score:8.82|P-value:4.71E-10 ID:SGTC_1547|Compound:harmine|FD-Score:15.00|P-value:9.78E-26 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:6.27|P-value:7.12E-6 ID:SGTC_1614|Compound:st002383|FD-Score:19.20|P-value:5.21E-41 ID:SGTC_1644|Compound:st010134|FD-Score:5.37|P-value:1.02E-4 ID:SGTC_1649|Compound:st011737|FD-Score:9.07|P-value:1.60E-10 ID:SGTC_1656|Compound:st012921|FD-Score:4.56|P-value:8.13E-4 ID:SGTC_1672|Compound:st016598|FD-Score:14.30|P-value:1.82E-23 ID:SGTC_1679|Compound:4130-1276|FD-Score:9.99|P-value:2.09E-12 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:9.50|P-value:2.23E-11 ID:SGTC_1736|Compound:st036774|FD-Score:4.84|P-value:4.07E-4 ID:SGTC_1787|Compound:fluconazole|FD-Score:-5.37|P-value:8.30E-5 ID:SGTC_1789|Compound:tunicamycin|FD-Score:6.33|P-value:5.88E-6 ID:SGTC_1797|Compound:st048695|FD-Score:4.68|P-value:6.14E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.10|P-value:1.20E-5 ID:SGTC_1874|Compound:staurosporine|FD-Score:15.60|P-value:1.36E-27 ID:SGTC_1877|Compound:wortmannin|FD-Score:6.93|P-value:7.89E-7 ID:SGTC_1907|Compound:st060210|FD-Score:12.00|P-value:4.83E-17 ID:SGTC_1933|Compound:st074711|FD-Score:8.63|P-value:1.08E-9 ID:SGTC_1959|Compound:st077091|FD-Score:6.01|P-value:1.57E-5 ID:SGTC_1982|Compound:st072467|FD-Score:4.48|P-value:9.80E-4 ID:SGTC_2003|Compound:4023581|FD-Score:11.90|P-value:8.22E-17 ID:SGTC_2007|Compound:4011539|FD-Score:20.70|P-value:4.31E-47 ID:SGTC_2009|Compound:4012297|FD-Score:19.10|P-value:1.38E-40 ID:SGTC_2016|Compound:5121758|FD-Score:7.12|P-value:3.98E-7 ID:SGTC_2028|Compound:5153890|FD-Score:17.90|P-value:5.45E-36 ID:SGTC_2036|Compound:5160441|FD-Score:7.45|P-value:1.20E-7 ID:SGTC_2049|Compound:5262831|FD-Score:7.22|P-value:2.86E-7 ID:SGTC_2050|Compound:5263056|FD-Score:10.50|P-value:1.79E-13 ID:SGTC_2057|Compound:5236571|FD-Score:6.23|P-value:7.95E-6 ID:SGTC_2132|Compound:5317594|FD-Score:6.17|P-value:9.59E-6 ID:SGTC_2149|Compound:5554786|FD-Score:17.60|P-value:1.60E-34 ID:SGTC_2210|Compound:7115885|FD-Score:20.50|P-value:2.45E-46 ID:SGTC_2241|Compound:6772625|FD-Score:5.03|P-value:2.51E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:6.36|P-value:5.29E-6 ID:SGTC_2254|Compound:7938975|FD-Score:5.81|P-value:2.88E-5 ID:SGTC_2257|Compound:7960413|FD-Score:5.85|P-value:2.55E-5 ID:SGTC_2272|Compound:7805186|FD-Score:18.10|P-value:1.32E-36 ID:SGTC_2286|Compound:7945697|FD-Score:12.70|P-value:4.98E-19 ID:SGTC_2289|Compound:7946404|FD-Score:7.45|P-value:1.21E-7 ID:SGTC_2300|Compound:7976697|FD-Score:11.20|P-value:4.62E-15 ID:SGTC_2384|Compound:9036245|FD-Score:5.42|P-value:8.89E-5 ID:SGTC_2399|Compound:5884133|FD-Score:12.60|P-value:8.13E-19 ID:SGTC_2430|Compound:5571206|FD-Score:7.39|P-value:1.51E-7 ID:SGTC_2488|Compound:5268135|FD-Score:4.84|P-value:4.13E-4 ID:SGTC_2489|Compound:cantharidin|FD-Score:17.30|P-value:1.71E-33 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:4.47|P-value:9.98E-4 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:11.30|P-value:2.14E-15 ID:SGTC_2581|Compound:avocatin a|FD-Score:6.35|P-value:5.40E-6 ID:SGTC_2584|Compound:androsterone|FD-Score:7.17|P-value:3.39E-7 ID:SGTC_2607|Compound:solasodine|FD-Score:6.71|P-value:1.65E-6 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:5.22|P-value:1.54E-4 ID:SGTC_2619|Compound:obliquin|FD-Score:18.40|P-value:1.44E-37 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:6.75|P-value:1.47E-6 ID:SGTC_2648|Compound:atorvastatin|FD-Score:6.23|P-value:8.10E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.86|P-value:3.94E-10 ID:SGTC_2694|Compound:st077685|FD-Score:5.36|P-value:1.05E-4 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:5.77|P-value:3.23E-5 ID:SGTC_2713|Compound:st079149|FD-Score:7.18|P-value:3.27E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:10.60|P-value:8.18E-14 ID:SGTC_2772|Compound:vinpocetine|FD-Score:4.91|P-value:3.47E-4 ID:SGTC_2776|Compound:terbinafine|FD-Score:35.30|P-value:1.78E-133 ID:SGTC_2777|Compound:climbazole|FD-Score:5.68|P-value:4.22E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:8.07|P-value:1.10E-8 ID:SGTC_2816|Compound:7982706|FD-Score:10.00|P-value:1.94E-12 ID:SGTC_2890|Compound:9046729|FD-Score:15.20|P-value:2.47E-26 ID:SGTC_2896|Compound:9052656|FD-Score:13.70|P-value:6.70E-22 ID:SGTC_2912|Compound:7964298|FD-Score:32.70|P-value:4.37E-115 ID:SGTC_2924|Compound:9010168|FD-Score:26.80|P-value:1.43E-77 ID:SGTC_2929|Compound:9013348|FD-Score:5.59|P-value:5.49E-5 ID:SGTC_2980|Compound:9014342|FD-Score:-4.76|P-value:4.21E-4 ID:SGTC_2997|Compound:9067075|FD-Score:16.20|P-value:1.05E-29 ID:SGTC_3006|Compound:9075424|FD-Score:7.82|P-value:2.98E-8 ID:SGTC_3007|Compound:9078383|FD-Score:4.89|P-value:3.62E-4 ID:SGTC_3016|Compound:9080866|FD-Score:-5.73|P-value:2.98E-5 ID:SGTC_3018|Compound:9082602|FD-Score:15.70|P-value:3.82E-28 ID:SGTC_3055|Compound:9094636|FD-Score:-5.28|P-value:1.07E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:16.40|P-value:1.51E-30 ID:SGTC_3060|Compound:1327-0027|FD-Score:14.30|P-value:1.20E-23 ID:SGTC_3063|Compound:1327-0034|FD-Score:18.10|P-value:1.68E-36 ID:SGTC_3064|Compound:1327-0027|FD-Score:7.85|P-value:2.68E-8 ID:SGTC_3078|Compound:9116413|FD-Score:9.45|P-value:2.73E-11 ID:SGTC_3092|Compound:9117248|FD-Score:6.20|P-value:8.95E-6 ID:SGTC_3099|Compound:9120367|FD-Score:4.49|P-value:9.67E-4 ID:SGTC_3122|Compound:9126309|FD-Score:8.75|P-value:6.37E-10 ID:SGTC_3129|Compound:9127257|FD-Score:-4.63|P-value:5.71E-4 ID:SGTC_3152|Compound:9099253|FD-Score:12.60|P-value:1.16E-18 ID:SGTC_3154|Compound:9100113|FD-Score:5.25|P-value:1.42E-4 ID:SGTC_3266|Compound:9136860|FD-Score:9.67|P-value:9.97E-12 ID:SGTC_3277|Compound:9138724|FD-Score:4.53|P-value:8.75E-4 ID:SGTC_3285|Compound:9112818|FD-Score:6.57|P-value:2.64E-6 ID:SGTC_3310|Compound:9130229|FD-Score:7.38|P-value:1.55E-7 ID:SGTC_3311|Compound:9131146|FD-Score:9.55|P-value:1.69E-11 ID:SGTC_3321|Compound:9137793|FD-Score:4.86|P-value:3.87E-4 ID:SGTC_3331|Compound:9141060|FD-Score:6.62|P-value:2.28E-6 ID:SGTC_3336|Compound:9143619|FD-Score:8.06|P-value:1.14E-8 ID:SGTC_3338|Compound:9144300|FD-Score:7.02|P-value:5.81E-7 ID:SGTC_3347|Compound:9188721|FD-Score:4.99|P-value:2.79E-4 ID:SGTC_3350|Compound:9150499|FD-Score:14.80|P-value:4.64E-25 ID:SGTC_3351|Compound:9150312|FD-Score:5.05|P-value:2.41E-4 ID:SGTC_3356|Compound:9151811|FD-Score:6.79|P-value:1.26E-6

Top fitness defect scores for YHR030C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_663 1486-0733 38.60 13.9 µM 6.35E-159 cell wall signaling 1 0
2 SGTC_2776 terbinafine 35.30 19.9 µM 1.78E-133 cell wall signaling 1 3.17E-273
3 SGTC_2912 7964298 32.70 10.9 µM 4.37E-115 cell wall 2 2.64E-235
4 SGTC_500 h-89 28.10 112.0 µM 3.83E-85 cell wall signaling 1 1.44E-173
5 SGTC_422 cantharidin 27.80 155.0 µM 1.84E-83 cell wall signaling 2 4.21E-170
6 SGTC_2924 9010168 26.80 62.8 µM 1.43E-77 cell wall signaling 1 5.85E-158
7 SGTC_369 0957-0393 25.50 4.5 µM 1.24E-70 cell wall signaling 1 1.17E-143
8 SGTC_360 0957-0399 24.60 1.0 µM 5.28E-66 cell wall 1 4.08E-134
9 SGTC_241 5hr heat shock (37°C) + cantharidin 21.60 155.4 µM 1.96E-51 cell wall signaling 4 4.31E-104
10 SGTC_2007 4011539 20.70 71.8 µM 4.31E-47 cell wall signaling 3 3.83E-95
11 SGTC_2210 7115885 20.50 190.4 µM 2.45E-46 cell wall signaling 1 1.37E-93
12 SGTC_367 0335-0881 20.30 7.1 µM 1.10E-45 ubiquinone biosynthesis & proteasome 2 3.01E-92
13 SGTC_137 0438-0332 19.80 85.4 µM 2.44E-43 ubiquinone biosynthesis & proteasome 5 2.06E-87
14 SGTC_1614 st002383 19.20 48.6 µM 5.21E-41 cell wall signaling 1 1.29E-82
15 SGTC_2009 4012297 19.10 12.1 µM 1.38E-40 cell wall signaling 3 9.60E-82
16 SGTC_138 0850-0259 18.90 40.9 µM 7.86E-40 cell wall 8 3.47E-80
17 SGTC_905 2-aminofluorene 18.70 215.0 µM 4.35E-39 cell wall signaling 2 1.17E-78
18 SGTC_71 0417-1750 18.60 47.8 µM 1.71E-38 Golgi 3 1.97E-77
19 SGTC_2619 obliquin 18.40 87.9 µM 1.44E-37 cell wall 4 1.58E-75
20 SGTC_2272 7805186 18.10 180.0 µM 1.32E-36 cell wall signaling 2 1.51E-73

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.777 0 YJL095W BCK1 hom Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
0.417 2.91E-140 YPR165W RHO1 het GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)
0.360 9.86E-103 YDL203C ACK1 hom Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria
0.358 3.18E-101 YLR331C_d JIP3_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2
0.347 4.45E-95 YLR332W MID2 hom O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p
0.307 1.40E-73 YGR196C FYV8 hom Protein of unknown function, required for survival upon exposure to K1 killer toxin
0.276 3.92E-59 YBR260C RGD1 hom GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization
0.269 4.04E-56 YOR008C SLG1 hom Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway; involved in maintenance of cell wall integrity; required for mitophagy; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response
0.266 4.18E-55 YPL089C RLM1 hom MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication
0.261 6.20E-53 YLL043W FPS1 hom Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress
0.242 1.26E-45 YJL099W CHS6 hom Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
0.231 1.22E-41 YBL006C LDB7 hom Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions
0.222 1.48E-38 YPR107C YTH1 het Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation
0.221 4.08E-38 YDR348C PAL1 hom Protein of unknown function thought to be involved in endocytosis; Pal1p physically interacts with Ede1p and is found at endocytic sites at the cell periphery during the early stages of endocytosis; green fluorescent protein (GFP)-fusion protein also localizes to the bud neck; potential Cdc28p substrate; similar to the S. pombe Pal1 protein; relocalizes from bud neck to cytoplasm upon DNA replication stress
0.220 9.68E-38 YCR094W CDC50 hom Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication