Putative GPI protein; transcription dependent upon Azf1p
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YHR126C deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Correlation | pval | ORF | Gene | Zygosity | Description |
---|---|---|---|---|---|
0.099 | 1.07E-8 | YOR190W | SPR1 | hom | Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance |
0.097 | 1.91E-8 | YOR023C | AHC1 | hom | Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex |
0.091 | 1.48E-7 | YDL168W | SFA1 | hom | Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase; formaldehyde dehydrogenase activity is glutathione-dependent; functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p; protein abundance increases in response to DNA replication stress |
0.089 | 2.17E-7 | YLR341W | SPO77 | hom | Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis |
0.088 | 3.64E-7 | YNL042W | BOP3 | hom | Protein of unknown function, potential Cdc28p substrate; overproduction confers resistance to methylmercury |
0.087 | 4.44E-7 | YJR106W | ECM27 | hom | Putative protein of unknown function; may play a role in cell wall biosynthesis, mutants are hypersensitive to Papulacandin B; null mutants have increased plasmid loss; displays a two-hybrid interaction with Pdr5p |
0.084 | 1.11E-6 | YJR098C_p | YJR098C_p | hom | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
0.083 | 1.28E-6 | YML063W | RPS1B | hom | Ribosomal protein 10 (rp10) of the small (40S) subunit; homologous to mammalian ribosomal protein S3A, no bacterial homolog; RPS1B has a paralog, RPS1A, that arose from the whole genome duplication |
0.083 | 1.41E-6 | YGR274C | TAF1 | het | TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation; possesses in vitro histone acetyltransferase activity but its role in vivo appears to be minor; involved in promoter binding and G1/S progression |
0.081 | 2.54E-6 | YCR010C | ADY2 | hom | Acetate transporter required for normal sporulation; phosphorylated in mitochondria; ADY2 has a paralog, ATO2, that arose from the whole genome duplication |
0.081 | 2.66E-6 | YBL069W | AST1 | hom | Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication |
0.080 | 3.27E-6 | YNL063W | MTQ1 | hom | S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene |
0.078 | 6.03E-6 | YOR118W | RTC5 | hom | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity |
0.076 | 9.21E-6 | YNL152W | INN1 | het | Essential protein that associates with contractile actomyosin ring; required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function; activates chitin synthase activity of Chs2p during cytokinesis |
0.073 | 2.23E-5 | YLR130C | ZRT2 | hom | Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor |