YHR170W / NMD3

Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex

Zygosity: Heterozygous strain
fixedexpanded
Profile for YHR170W / NMD3

Click on Significant Values for Screen Details ID:SGTC_49|Compound:0717-0965|FD-Score:6.81|P-value:1.58E-6 ID:SGTC_62|Compound:0180-0423|FD-Score:6.68|P-value:2.45E-6 ID:SGTC_85|Compound:0868-0259|FD-Score:6.72|P-value:2.14E-6 ID:SGTC_97|Compound:0535-0701|FD-Score:10.40|P-value:6.00E-13 ID:SGTC_110|Compound:0850-0284|FD-Score:-4.61|P-value:8.10E-4 ID:SGTC_115|Compound:0527-0192|FD-Score:4.57|P-value:8.83E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:8.06|P-value:1.71E-8 ID:SGTC_121|Compound:0557-0495|FD-Score:9.70|P-value:1.60E-11 ID:SGTC_135|Compound:0933-0004|FD-Score:8.70|P-value:1.29E-9 ID:SGTC_136|Compound:0097-0015|FD-Score:7.84|P-value:3.99E-8 ID:SGTC_183|Compound:3914-0051|FD-Score:7.66|P-value:8.00E-8 ID:SGTC_191|Compound:3914-0123|FD-Score:8.08|P-value:1.61E-8 ID:SGTC_198|Compound:3454-2873|FD-Score:6.91|P-value:1.14E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-5.15|P-value:2.17E-4 ID:SGTC_359|Compound:0081-0058|FD-Score:4.82|P-value:4.87E-4 ID:SGTC_403|Compound:arphamenine a|FD-Score:5.61|P-value:6.20E-5 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.68|P-value:6.76E-4 ID:SGTC_522|Compound:1273-0010|FD-Score:4.77|P-value:5.43E-4 ID:SGTC_529|Compound:4076-0302|FD-Score:5.06|P-value:2.66E-4 ID:SGTC_530|Compound:4358-1714|FD-Score:4.58|P-value:8.50E-4 ID:SGTC_558|Compound:k064-0027|FD-Score:6.50|P-value:4.30E-6 ID:SGTC_570|Compound:0987-0065|FD-Score:8.89|P-value:5.80E-10 ID:SGTC_579|Compound:4491-1009|FD-Score:7.72|P-value:6.36E-8 ID:SGTC_618|Compound:k072-0232|FD-Score:8.05|P-value:1.80E-8 ID:SGTC_645|Compound:0845-0943|FD-Score:6.12|P-value:1.42E-5 ID:SGTC_685|Compound:1278-0033|FD-Score:6.85|P-value:1.39E-6 ID:SGTC_686|Compound:1319-0111|FD-Score:5.42|P-value:1.02E-4 ID:SGTC_706|Compound:4262-0057|FD-Score:6.82|P-value:1.52E-6 ID:SGTC_716|Compound:1683-5115|FD-Score:4.53|P-value:9.67E-4 ID:SGTC_718|Compound:1130-0073|FD-Score:-4.91|P-value:3.96E-4 ID:SGTC_722|Compound:3534-0461|FD-Score:6.01|P-value:1.94E-5 ID:SGTC_765|Compound:1319-0117|FD-Score:10.30|P-value:8.89E-13 ID:SGTC_773|Compound:4358-1457|FD-Score:7.18|P-value:4.47E-7 ID:SGTC_810|Compound:3825-7150|FD-Score:6.34|P-value:7.23E-6 ID:SGTC_845|Compound:0330-0138|FD-Score:-4.84|P-value:4.66E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:-5.28|P-value:1.54E-4 ID:SGTC_853|Compound:0419-0306|FD-Score:4.90|P-value:3.94E-4 ID:SGTC_866|Compound:0495-0101|FD-Score:8.01|P-value:2.07E-8 ID:SGTC_887|Compound:0885-0007|FD-Score:4.78|P-value:5.36E-4 ID:SGTC_953|Compound:1188-0045|FD-Score:10.30|P-value:9.29E-13 ID:SGTC_954|Compound:1189-0853|FD-Score:6.21|P-value:1.07E-5 ID:SGTC_990|Compound:3985-0011|FD-Score:5.44|P-value:9.70E-5 ID:SGTC_1010|Compound:4112-3296|FD-Score:5.29|P-value:1.47E-4 ID:SGTC_1015|Compound:4130-4525|FD-Score:5.82|P-value:3.39E-5 ID:SGTC_1054|Compound:3429-0080|FD-Score:5.45|P-value:9.46E-5 ID:SGTC_1070|Compound:indatraline|FD-Score:7.45|P-value:1.69E-7 ID:SGTC_1081|Compound:sertraline|FD-Score:5.32|P-value:1.34E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:12.70|P-value:1.97E-18 ID:SGTC_1136|Compound:pergolide|FD-Score:6.86|P-value:1.34E-6 ID:SGTC_1185|Compound:1319-0113|FD-Score:4.94|P-value:3.61E-4 ID:SGTC_1226|Compound:3909-7979|FD-Score:10.80|P-value:7.24E-14 ID:SGTC_1229|Compound:0139-0193|FD-Score:-6.15|P-value:1.30E-5 ID:SGTC_1239|Compound:0337-0584|FD-Score:-5.62|P-value:6.19E-5 ID:SGTC_1247|Compound:0448-0043|FD-Score:9.40|P-value:6.17E-11 ID:SGTC_1250|Compound:0485-0349|FD-Score:-5.90|P-value:2.75E-5 ID:SGTC_1255|Compound:0566-0045|FD-Score:-4.74|P-value:5.98E-4 ID:SGTC_1261|Compound:0712-0010|FD-Score:8.31|P-value:6.38E-9 ID:SGTC_1269|Compound:0831-0796|FD-Score:6.86|P-value:1.33E-6 ID:SGTC_1383|Compound:3049-0032|FD-Score:6.50|P-value:4.37E-6 ID:SGTC_1404|Compound:3909-7820|FD-Score:4.91|P-value:3.85E-4 ID:SGTC_1407|Compound:3909-7909|FD-Score:4.52|P-value:9.93E-4 ID:SGTC_1522|Compound:st012842|FD-Score:5.68|P-value:5.04E-5 ID:SGTC_1523|Compound:st012844|FD-Score:6.39|P-value:6.10E-6 ID:SGTC_1556|Compound:plumbagin|FD-Score:-4.80|P-value:5.25E-4 ID:SGTC_1592|Compound:4',5'-dihydroxyflavone|FD-Score:9.94|P-value:5.19E-12 ID:SGTC_1604|Compound:st002052|FD-Score:4.87|P-value:4.32E-4 ID:SGTC_1606|Compound:st000094|FD-Score:4.78|P-value:5.33E-4 ID:SGTC_1612|Compound:st002233|FD-Score:5.13|P-value:2.22E-4 ID:SGTC_1663|Compound:st014140|FD-Score:5.41|P-value:1.07E-4 ID:SGTC_1664|Compound:st014217|FD-Score:5.58|P-value:6.67E-5 ID:SGTC_1674|Compound:st016616|FD-Score:5.18|P-value:1.94E-4 ID:SGTC_1675|Compound:st018485|FD-Score:5.82|P-value:3.38E-5 ID:SGTC_1676|Compound:st018489|FD-Score:7.41|P-value:1.94E-7 ID:SGTC_1678|Compound:st019265|FD-Score:4.64|P-value:7.37E-4 ID:SGTC_1721|Compound:st082152|FD-Score:6.51|P-value:4.19E-6 ID:SGTC_1733|Compound:st037357|FD-Score:8.04|P-value:1.84E-8 ID:SGTC_1755|Compound:st041960|FD-Score:5.15|P-value:2.10E-4 ID:SGTC_1775|Compound:st081588|FD-Score:11.20|P-value:8.35E-15 ID:SGTC_1786|Compound:berberine|FD-Score:9.38|P-value:6.85E-11 ID:SGTC_1797|Compound:st048695|FD-Score:6.74|P-value:1.96E-6 ID:SGTC_1827|Compound:berberine|FD-Score:11.50|P-value:2.04E-15 ID:SGTC_1829|Compound:berberine|FD-Score:13.50|P-value:1.38E-20 ID:SGTC_1855|Compound:st056195|FD-Score:4.67|P-value:6.93E-4 ID:SGTC_1886|Compound:st057356|FD-Score:9.03|P-value:3.20E-10 ID:SGTC_1908|Compound:st060353|FD-Score:4.57|P-value:8.78E-4 ID:SGTC_1940|Compound:st075990|FD-Score:6.50|P-value:4.29E-6 ID:SGTC_1945|Compound:st075991|FD-Score:4.87|P-value:4.23E-4 ID:SGTC_1958|Compound:st076513|FD-Score:11.20|P-value:1.17E-14 ID:SGTC_1971|Compound:st069429|FD-Score:5.27|P-value:1.55E-4 ID:SGTC_1999|Compound:st074831|FD-Score:4.91|P-value:3.85E-4 ID:SGTC_2005|Compound:4024620|FD-Score:4.54|P-value:9.48E-4 ID:SGTC_2010|Compound:4012422|FD-Score:5.85|P-value:3.13E-5 ID:SGTC_2011|Compound:4012611|FD-Score:5.40|P-value:1.10E-4 ID:SGTC_2020|Compound:4017018|FD-Score:-4.75|P-value:5.85E-4 ID:SGTC_2078|Compound:5212016|FD-Score:8.72|P-value:1.22E-9 ID:SGTC_2100|Compound:5377183|FD-Score:8.21|P-value:9.72E-9 ID:SGTC_2131|Compound:toluylene red|FD-Score:9.33|P-value:8.71E-11 ID:SGTC_2160|Compound:5660466|FD-Score:5.10|P-value:2.39E-4 ID:SGTC_2172|Compound:5754775|FD-Score:6.04|P-value:1.78E-5 ID:SGTC_2204|Compound:7233102|FD-Score:5.73|P-value:4.42E-5 ID:SGTC_2260|Compound:7964312|FD-Score:5.13|P-value:2.24E-4 ID:SGTC_2305|Compound:7443522|FD-Score:7.27|P-value:3.25E-7 ID:SGTC_2308|Compound:7584454|FD-Score:-4.78|P-value:5.44E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-5.72|P-value:4.62E-5 ID:SGTC_2382|Compound:9035899|FD-Score:5.34|P-value:1.29E-4 ID:SGTC_2404|Compound:5161160|FD-Score:5.06|P-value:2.63E-4 ID:SGTC_2507|Compound:purpurin|FD-Score:-4.55|P-value:9.45E-4 ID:SGTC_2511|Compound:berberine|FD-Score:5.40|P-value:1.09E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-5.94|P-value:2.49E-5 ID:SGTC_2549|Compound:cedrol|FD-Score:5.94|P-value:2.38E-5 ID:SGTC_2552|Compound:juarezic acid|FD-Score:-5.88|P-value:2.94E-5 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:6.91|P-value:1.13E-6 ID:SGTC_2590|Compound:3,4',5',6',7'-pentamethoxyflavone|FD-Score:6.72|P-value:2.11E-6 ID:SGTC_2593|Compound:nobiletin|FD-Score:4.70|P-value:6.42E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:6.60|P-value:3.10E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:-4.94|P-value:3.71E-4 ID:SGTC_2615|Compound:purpurogallin-4-carboxylic acid|FD-Score:-6.19|P-value:1.18E-5 ID:SGTC_2645|Compound:abamectin|FD-Score:-6.02|P-value:1.91E-5 ID:SGTC_2724|Compound:maprotiline|FD-Score:4.53|P-value:9.65E-4 ID:SGTC_2772|Compound:vinpocetine|FD-Score:4.75|P-value:5.66E-4 ID:SGTC_2774|Compound:tamoxifen|FD-Score:5.15|P-value:2.09E-4 ID:SGTC_2809|Compound:7964133|FD-Score:10.30|P-value:1.05E-12 ID:SGTC_2818|Compound:7996756|FD-Score:4.59|P-value:8.30E-4 ID:SGTC_2825|Compound:7998094|FD-Score:5.43|P-value:1.01E-4 ID:SGTC_2877|Compound:9040724|FD-Score:-5.31|P-value:1.42E-4 ID:SGTC_2909|Compound:7941780|FD-Score:5.22|P-value:1.74E-4 ID:SGTC_2913|Compound:7966556|FD-Score:6.39|P-value:6.01E-6 ID:SGTC_2937|Compound:9044753|FD-Score:5.76|P-value:4.07E-5 ID:SGTC_2983|Compound:9022671|FD-Score:11.00|P-value:2.42E-14 ID:SGTC_3069|Compound:9117009|FD-Score:6.88|P-value:1.26E-6 ID:SGTC_3073|Compound:9114972|FD-Score:7.35|P-value:2.40E-7 ID:SGTC_3081|Compound:9117243|FD-Score:6.65|P-value:2.65E-6 ID:SGTC_3093|Compound:9117344|FD-Score:7.31|P-value:2.83E-7 ID:SGTC_3100|Compound:9120536|FD-Score:6.26|P-value:9.06E-6 ID:SGTC_3101|Compound:9120531|FD-Score:5.65|P-value:5.42E-5 ID:SGTC_3126|Compound:9127922|FD-Score:12.90|P-value:5.50E-19 ID:SGTC_3127|Compound:9126946|FD-Score:5.43|P-value:9.94E-5 ID:SGTC_3160|Compound:9100216|FD-Score:-4.60|P-value:8.37E-4 ID:SGTC_3168|Compound:9103419|FD-Score:6.84|P-value:1.44E-6 ID:SGTC_3170|Compound:9103054|FD-Score:10.50|P-value:2.81E-13 ID:SGTC_3178|Compound:9107506|FD-Score:5.22|P-value:1.75E-4 ID:SGTC_3185|Compound:9108267|FD-Score:10.00|P-value:3.36E-12 ID:SGTC_3222|Compound:9128301|FD-Score:7.14|P-value:5.20E-7 ID:SGTC_3225|Compound:9130819|FD-Score:4.94|P-value:3.61E-4 ID:SGTC_3249|Compound:9135183|FD-Score:5.10|P-value:2.38E-4 ID:SGTC_3251|Compound:9135047|FD-Score:5.84|P-value:3.21E-5 ID:SGTC_3259|Compound:9138485|FD-Score:5.30|P-value:1.42E-4 ID:SGTC_3269|Compound:9137823|FD-Score:5.14|P-value:2.18E-4 ID:SGTC_3276|Compound:9139060|FD-Score:7.21|P-value:4.06E-7 ID:SGTC_3280|Compound:9140961|FD-Score:6.66|P-value:2.61E-6 ID:SGTC_49|Compound:0717-0965|FD-Score:6.81|P-value:1.58E-6 ID:SGTC_62|Compound:0180-0423|FD-Score:6.68|P-value:2.45E-6 ID:SGTC_85|Compound:0868-0259|FD-Score:6.72|P-value:2.14E-6 ID:SGTC_97|Compound:0535-0701|FD-Score:10.40|P-value:6.00E-13 ID:SGTC_110|Compound:0850-0284|FD-Score:-4.61|P-value:8.10E-4 ID:SGTC_115|Compound:0527-0192|FD-Score:4.57|P-value:8.83E-4 ID:SGTC_117|Compound:lucigenin|FD-Score:8.06|P-value:1.71E-8 ID:SGTC_121|Compound:0557-0495|FD-Score:9.70|P-value:1.60E-11 ID:SGTC_135|Compound:0933-0004|FD-Score:8.70|P-value:1.29E-9 ID:SGTC_136|Compound:0097-0015|FD-Score:7.84|P-value:3.99E-8 ID:SGTC_183|Compound:3914-0051|FD-Score:7.66|P-value:8.00E-8 ID:SGTC_191|Compound:3914-0123|FD-Score:8.08|P-value:1.61E-8 ID:SGTC_198|Compound:3454-2873|FD-Score:6.91|P-value:1.14E-6 ID:SGTC_299|Compound:1273-0059|FD-Score:-5.15|P-value:2.17E-4 ID:SGTC_359|Compound:0081-0058|FD-Score:4.82|P-value:4.87E-4 ID:SGTC_403|Compound:arphamenine a|FD-Score:5.61|P-value:6.20E-5 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.68|P-value:6.76E-4 ID:SGTC_522|Compound:1273-0010|FD-Score:4.77|P-value:5.43E-4 ID:SGTC_529|Compound:4076-0302|FD-Score:5.06|P-value:2.66E-4 ID:SGTC_530|Compound:4358-1714|FD-Score:4.58|P-value:8.50E-4 ID:SGTC_558|Compound:k064-0027|FD-Score:6.50|P-value:4.30E-6 ID:SGTC_570|Compound:0987-0065|FD-Score:8.89|P-value:5.80E-10 ID:SGTC_579|Compound:4491-1009|FD-Score:7.72|P-value:6.36E-8 ID:SGTC_618|Compound:k072-0232|FD-Score:8.05|P-value:1.80E-8 ID:SGTC_645|Compound:0845-0943|FD-Score:6.12|P-value:1.42E-5 ID:SGTC_685|Compound:1278-0033|FD-Score:6.85|P-value:1.39E-6 ID:SGTC_686|Compound:1319-0111|FD-Score:5.42|P-value:1.02E-4 ID:SGTC_706|Compound:4262-0057|FD-Score:6.82|P-value:1.52E-6 ID:SGTC_716|Compound:1683-5115|FD-Score:4.53|P-value:9.67E-4 ID:SGTC_718|Compound:1130-0073|FD-Score:-4.91|P-value:3.96E-4 ID:SGTC_722|Compound:3534-0461|FD-Score:6.01|P-value:1.94E-5 ID:SGTC_765|Compound:1319-0117|FD-Score:10.30|P-value:8.89E-13 ID:SGTC_773|Compound:4358-1457|FD-Score:7.18|P-value:4.47E-7 ID:SGTC_810|Compound:3825-7150|FD-Score:6.34|P-value:7.23E-6 ID:SGTC_845|Compound:0330-0138|FD-Score:-4.84|P-value:4.66E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:-5.28|P-value:1.54E-4 ID:SGTC_853|Compound:0419-0306|FD-Score:4.90|P-value:3.94E-4 ID:SGTC_866|Compound:0495-0101|FD-Score:8.01|P-value:2.07E-8 ID:SGTC_887|Compound:0885-0007|FD-Score:4.78|P-value:5.36E-4 ID:SGTC_953|Compound:1188-0045|FD-Score:10.30|P-value:9.29E-13 ID:SGTC_954|Compound:1189-0853|FD-Score:6.21|P-value:1.07E-5 ID:SGTC_990|Compound:3985-0011|FD-Score:5.44|P-value:9.70E-5 ID:SGTC_1010|Compound:4112-3296|FD-Score:5.29|P-value:1.47E-4 ID:SGTC_1015|Compound:4130-4525|FD-Score:5.82|P-value:3.39E-5 ID:SGTC_1054|Compound:3429-0080|FD-Score:5.45|P-value:9.46E-5 ID:SGTC_1070|Compound:indatraline|FD-Score:7.45|P-value:1.69E-7 ID:SGTC_1081|Compound:sertraline|FD-Score:5.32|P-value:1.34E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:12.70|P-value:1.97E-18 ID:SGTC_1136|Compound:pergolide|FD-Score:6.86|P-value:1.34E-6 ID:SGTC_1185|Compound:1319-0113|FD-Score:4.94|P-value:3.61E-4 ID:SGTC_1226|Compound:3909-7979|FD-Score:10.80|P-value:7.24E-14 ID:SGTC_1229|Compound:0139-0193|FD-Score:-6.15|P-value:1.30E-5 ID:SGTC_1239|Compound:0337-0584|FD-Score:-5.62|P-value:6.19E-5 ID:SGTC_1247|Compound:0448-0043|FD-Score:9.40|P-value:6.17E-11 ID:SGTC_1250|Compound:0485-0349|FD-Score:-5.90|P-value:2.75E-5 ID:SGTC_1255|Compound:0566-0045|FD-Score:-4.74|P-value:5.98E-4 ID:SGTC_1261|Compound:0712-0010|FD-Score:8.31|P-value:6.38E-9 ID:SGTC_1269|Compound:0831-0796|FD-Score:6.86|P-value:1.33E-6 ID:SGTC_1383|Compound:3049-0032|FD-Score:6.50|P-value:4.37E-6 ID:SGTC_1404|Compound:3909-7820|FD-Score:4.91|P-value:3.85E-4 ID:SGTC_1407|Compound:3909-7909|FD-Score:4.52|P-value:9.93E-4 ID:SGTC_1522|Compound:st012842|FD-Score:5.68|P-value:5.04E-5 ID:SGTC_1523|Compound:st012844|FD-Score:6.39|P-value:6.10E-6 ID:SGTC_1556|Compound:plumbagin|FD-Score:-4.80|P-value:5.25E-4 ID:SGTC_1592|Compound:4',5'-dihydroxyflavone|FD-Score:9.94|P-value:5.19E-12 ID:SGTC_1604|Compound:st002052|FD-Score:4.87|P-value:4.32E-4 ID:SGTC_1606|Compound:st000094|FD-Score:4.78|P-value:5.33E-4 ID:SGTC_1612|Compound:st002233|FD-Score:5.13|P-value:2.22E-4 ID:SGTC_1663|Compound:st014140|FD-Score:5.41|P-value:1.07E-4 ID:SGTC_1664|Compound:st014217|FD-Score:5.58|P-value:6.67E-5 ID:SGTC_1674|Compound:st016616|FD-Score:5.18|P-value:1.94E-4 ID:SGTC_1675|Compound:st018485|FD-Score:5.82|P-value:3.38E-5 ID:SGTC_1676|Compound:st018489|FD-Score:7.41|P-value:1.94E-7 ID:SGTC_1678|Compound:st019265|FD-Score:4.64|P-value:7.37E-4 ID:SGTC_1721|Compound:st082152|FD-Score:6.51|P-value:4.19E-6 ID:SGTC_1733|Compound:st037357|FD-Score:8.04|P-value:1.84E-8 ID:SGTC_1755|Compound:st041960|FD-Score:5.15|P-value:2.10E-4 ID:SGTC_1775|Compound:st081588|FD-Score:11.20|P-value:8.35E-15 ID:SGTC_1786|Compound:berberine|FD-Score:9.38|P-value:6.85E-11 ID:SGTC_1797|Compound:st048695|FD-Score:6.74|P-value:1.96E-6 ID:SGTC_1827|Compound:berberine|FD-Score:11.50|P-value:2.04E-15 ID:SGTC_1829|Compound:berberine|FD-Score:13.50|P-value:1.38E-20 ID:SGTC_1855|Compound:st056195|FD-Score:4.67|P-value:6.93E-4 ID:SGTC_1886|Compound:st057356|FD-Score:9.03|P-value:3.20E-10 ID:SGTC_1908|Compound:st060353|FD-Score:4.57|P-value:8.78E-4 ID:SGTC_1940|Compound:st075990|FD-Score:6.50|P-value:4.29E-6 ID:SGTC_1945|Compound:st075991|FD-Score:4.87|P-value:4.23E-4 ID:SGTC_1958|Compound:st076513|FD-Score:11.20|P-value:1.17E-14 ID:SGTC_1971|Compound:st069429|FD-Score:5.27|P-value:1.55E-4 ID:SGTC_1999|Compound:st074831|FD-Score:4.91|P-value:3.85E-4 ID:SGTC_2005|Compound:4024620|FD-Score:4.54|P-value:9.48E-4 ID:SGTC_2010|Compound:4012422|FD-Score:5.85|P-value:3.13E-5 ID:SGTC_2011|Compound:4012611|FD-Score:5.40|P-value:1.10E-4 ID:SGTC_2020|Compound:4017018|FD-Score:-4.75|P-value:5.85E-4 ID:SGTC_2078|Compound:5212016|FD-Score:8.72|P-value:1.22E-9 ID:SGTC_2100|Compound:5377183|FD-Score:8.21|P-value:9.72E-9 ID:SGTC_2131|Compound:toluylene red|FD-Score:9.33|P-value:8.71E-11 ID:SGTC_2160|Compound:5660466|FD-Score:5.10|P-value:2.39E-4 ID:SGTC_2172|Compound:5754775|FD-Score:6.04|P-value:1.78E-5 ID:SGTC_2204|Compound:7233102|FD-Score:5.73|P-value:4.42E-5 ID:SGTC_2260|Compound:7964312|FD-Score:5.13|P-value:2.24E-4 ID:SGTC_2305|Compound:7443522|FD-Score:7.27|P-value:3.25E-7 ID:SGTC_2308|Compound:7584454|FD-Score:-4.78|P-value:5.44E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-5.72|P-value:4.62E-5 ID:SGTC_2382|Compound:9035899|FD-Score:5.34|P-value:1.29E-4 ID:SGTC_2404|Compound:5161160|FD-Score:5.06|P-value:2.63E-4 ID:SGTC_2507|Compound:purpurin|FD-Score:-4.55|P-value:9.45E-4 ID:SGTC_2511|Compound:berberine|FD-Score:5.40|P-value:1.09E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-5.94|P-value:2.49E-5 ID:SGTC_2549|Compound:cedrol|FD-Score:5.94|P-value:2.38E-5 ID:SGTC_2552|Compound:juarezic acid|FD-Score:-5.88|P-value:2.94E-5 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:6.91|P-value:1.13E-6 ID:SGTC_2590|Compound:3,4',5',6',7'-pentamethoxyflavone|FD-Score:6.72|P-value:2.11E-6 ID:SGTC_2593|Compound:nobiletin|FD-Score:4.70|P-value:6.42E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:6.60|P-value:3.10E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:-4.94|P-value:3.71E-4 ID:SGTC_2615|Compound:purpurogallin-4-carboxylic acid|FD-Score:-6.19|P-value:1.18E-5 ID:SGTC_2645|Compound:abamectin|FD-Score:-6.02|P-value:1.91E-5 ID:SGTC_2724|Compound:maprotiline|FD-Score:4.53|P-value:9.65E-4 ID:SGTC_2772|Compound:vinpocetine|FD-Score:4.75|P-value:5.66E-4 ID:SGTC_2774|Compound:tamoxifen|FD-Score:5.15|P-value:2.09E-4 ID:SGTC_2809|Compound:7964133|FD-Score:10.30|P-value:1.05E-12 ID:SGTC_2818|Compound:7996756|FD-Score:4.59|P-value:8.30E-4 ID:SGTC_2825|Compound:7998094|FD-Score:5.43|P-value:1.01E-4 ID:SGTC_2877|Compound:9040724|FD-Score:-5.31|P-value:1.42E-4 ID:SGTC_2909|Compound:7941780|FD-Score:5.22|P-value:1.74E-4 ID:SGTC_2913|Compound:7966556|FD-Score:6.39|P-value:6.01E-6 ID:SGTC_2937|Compound:9044753|FD-Score:5.76|P-value:4.07E-5 ID:SGTC_2983|Compound:9022671|FD-Score:11.00|P-value:2.42E-14 ID:SGTC_3069|Compound:9117009|FD-Score:6.88|P-value:1.26E-6 ID:SGTC_3073|Compound:9114972|FD-Score:7.35|P-value:2.40E-7 ID:SGTC_3081|Compound:9117243|FD-Score:6.65|P-value:2.65E-6 ID:SGTC_3093|Compound:9117344|FD-Score:7.31|P-value:2.83E-7 ID:SGTC_3100|Compound:9120536|FD-Score:6.26|P-value:9.06E-6 ID:SGTC_3101|Compound:9120531|FD-Score:5.65|P-value:5.42E-5 ID:SGTC_3126|Compound:9127922|FD-Score:12.90|P-value:5.50E-19 ID:SGTC_3127|Compound:9126946|FD-Score:5.43|P-value:9.94E-5 ID:SGTC_3160|Compound:9100216|FD-Score:-4.60|P-value:8.37E-4 ID:SGTC_3168|Compound:9103419|FD-Score:6.84|P-value:1.44E-6 ID:SGTC_3170|Compound:9103054|FD-Score:10.50|P-value:2.81E-13 ID:SGTC_3178|Compound:9107506|FD-Score:5.22|P-value:1.75E-4 ID:SGTC_3185|Compound:9108267|FD-Score:10.00|P-value:3.36E-12 ID:SGTC_3222|Compound:9128301|FD-Score:7.14|P-value:5.20E-7 ID:SGTC_3225|Compound:9130819|FD-Score:4.94|P-value:3.61E-4 ID:SGTC_3249|Compound:9135183|FD-Score:5.10|P-value:2.38E-4 ID:SGTC_3251|Compound:9135047|FD-Score:5.84|P-value:3.21E-5 ID:SGTC_3259|Compound:9138485|FD-Score:5.30|P-value:1.42E-4 ID:SGTC_3269|Compound:9137823|FD-Score:5.14|P-value:2.18E-4 ID:SGTC_3276|Compound:9139060|FD-Score:7.21|P-value:4.06E-7 ID:SGTC_3280|Compound:9140961|FD-Score:6.66|P-value:2.61E-6

Top fitness defect scores for YHR170W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1829 berberine 13.50 14.4 µM 1.38E-20 60S ribosome export 2 9.33E-42 3.71
2 SGTC_3126 9127922 12.90 49.5 µM 5.50E-19 fatty acid desaturase (OLE1) 3 2.35E-38 2.30
3 SGTC_1130 3454-2858 12.70 15.9 µM 1.97E-18 NEO1 2 3.50E-37 4.66
4 SGTC_1827 berberine 11.50 7.2 µM 2.04E-15 60S ribosome export 1 8.77E-31 2.06
5 SGTC_1775 st081588 11.20 35.2 µM 8.35E-15 60S ribosome export 2 1.73E-29 4.69
6 SGTC_1958 st076513 11.20 41.9 µM 1.17E-14 60S ribosome export 2 3.54E-29 5.92
7 SGTC_2983 9022671 11.00 13.0 µM 2.42E-14 60S ribosome export 1 1.65E-28 3.93
8 SGTC_1226 3909-7979 10.80 35.4 µM 7.24E-14 1 1.68E-27 4.57
9 SGTC_3170 9103054 10.50 49.5 µM 2.81E-13 60S ribosome export 1 2.97E-26 4.03
10 SGTC_97 0535-0701 10.40 19.1 µM 6.00E-13 60S ribosome export 3 1.47E-25 2.31
11 SGTC_765 1319-0117 10.30 244.0 µM 8.89E-13 60S ribosome export 2 3.39E-25 3.66
12 SGTC_953 1188-0045 10.30 9.7 µM 9.29E-13 60S ribosome export 1 3.72E-25 3.28
13 SGTC_2809 7964133 10.30 13.0 µM 1.05E-12 60S ribosome export 2 4.82E-25 4.45
14 SGTC_3185 9108267 10.00 49.5 µM 3.36E-12 60S ribosome export 1 5.65E-24 3.42
15 SGTC_1592 4',5'-dihydroxyflavone 9.94 8.8 µM 5.19E-12 60S ribosome export 2 1.41E-23 3.03
16 SGTC_121 0557-0495 9.70 61.3 µM 1.60E-11 calcium & mitochondrial duress 2 1.52E-22 2.65
17 SGTC_1247 0448-0043 9.40 5.8 µM 6.17E-11 ERG2 2 2.64E-21 2.18
18 SGTC_1786 berberine 9.38 21.6 µM 6.85E-11 60S ribosome export 4 3.30E-21 1.18
19 SGTC_2131 toluylene red 9.33 5.3 µM 8.71E-11 60S ribosome export 2 5.47E-21 2.60
20 SGTC_1886 st057356 9.03 49.9 µM 3.20E-10 60S ribosome export 1 8.51E-20 2.88

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.689 0 YGL099W LSG1 het Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm
0.318 1.61E-79 YOR072W_d YOR072W_d hom Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive
0.213 1.19E-35 YPL093W NOG1 het Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
0.186 1.94E-27 YBR267W REI1 hom Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network
0.180 1.15E-25 YPR016C TIF6 het Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits
0.163 2.52E-21 YOL068C HST1 hom NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance
0.158 5.20E-20 YOR279C RFM1 hom DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance
0.154 2.99E-19 YDR083W RRP8 hom Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1
0.139 8.60E-16 YLR359W ADE13 het Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency
0.131 2.39E-14 YER112W LSM4 het Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; forms cytoplasmic foci upon DNA replication stress
0.126 3.06E-13 YGR148C RPL24B hom Ribosomal 60S subunit protein L24B; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24B has a paralog, RPL24A, that arose from the whole genome duplication
0.118 6.26E-12 YGL055W OLE1 het Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
0.111 1.16E-10 YNR053C NOG2 het Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
0.107 5.76E-10 YBR190W_d YBR190W_d het Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W
0.105 1.03E-9 YNL227C JJJ1 hom Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis