YIL154C / IMP2'

Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat

Zygosity: Homozygous strain
fixedexpanded
Profile for YIL154C / IMP2

Click on Significant Values for Screen Details ID:SGTC_9|Compound:0092-0002|FD-Score:5.18|P-value:1.38E-5 ID:SGTC_29|Compound:0299-0004|FD-Score:8.13|P-value:1.96E-11 ID:SGTC_33|Compound:0986-0033|FD-Score:18.40|P-value:2.43E-51 ID:SGTC_39|Compound:0986-0283|FD-Score:14.40|P-value:6.54E-32 ID:SGTC_40|Compound:0327-0103|FD-Score:10.80|P-value:9.68E-19 ID:SGTC_54|Compound:0159-0055|FD-Score:23.10|P-value:2.49E-79 ID:SGTC_55|Compound:0767-0285|FD-Score:9.59|P-value:3.15E-15 ID:SGTC_57|Compound:miconazole|FD-Score:4.25|P-value:2.99E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:-6.76|P-value:1.28E-8 ID:SGTC_65|Compound:0798-0905|FD-Score:20.40|P-value:2.13E-62 ID:SGTC_68|Compound:0986-0284|FD-Score:19.30|P-value:2.64E-56 ID:SGTC_81|Compound:0411-0046|FD-Score:11.50|P-value:3.86E-21 ID:SGTC_96|Compound:0929-0093|FD-Score:16.20|P-value:3.32E-40 ID:SGTC_103|Compound:0844-0104|FD-Score:-5.13|P-value:1.12E-5 ID:SGTC_117|Compound:lucigenin|FD-Score:13.10|P-value:7.86E-27 ID:SGTC_118|Compound:0083-0097|FD-Score:-4.29|P-value:1.91E-4 ID:SGTC_120|Compound:rhodamine 6G|FD-Score:6.99|P-value:7.06E-9 ID:SGTC_121|Compound:0557-0495|FD-Score:12.10|P-value:2.36E-23 ID:SGTC_127|Compound:0180-0333|FD-Score:7.29|P-value:1.62E-9 ID:SGTC_144|Compound:4161-2749|FD-Score:4.90|P-value:3.71E-5 ID:SGTC_146|Compound:3448-8650|FD-Score:17.50|P-value:2.44E-46 ID:SGTC_178|Compound:4092-0806|FD-Score:19.90|P-value:1.91E-59 ID:SGTC_187|Compound:1488-2104|FD-Score:15.00|P-value:1.17E-34 ID:SGTC_197|Compound:4544-0043|FD-Score:11.70|P-value:1.03E-21 ID:SGTC_201|Compound:4262-0159|FD-Score:7.88|P-value:7.58E-11 ID:SGTC_217|Compound:ketoconazole|FD-Score:5.75|P-value:1.61E-6 ID:SGTC_218|Compound:alverine citrate|FD-Score:7.94|P-value:5.45E-11 ID:SGTC_234|Compound:nsc-17383|FD-Score:5.44|P-value:5.21E-6 ID:SGTC_236|Compound:1509-0011|FD-Score:10.40|P-value:1.21E-17 ID:SGTC_252|Compound:miconazole|FD-Score:4.79|P-value:5.42E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:4.36|P-value:2.15E-4 ID:SGTC_256|Compound:clotrimazole|FD-Score:7.28|P-value:1.72E-9 ID:SGTC_278|Compound:4092-0821|FD-Score:6.16|P-value:2.96E-7 ID:SGTC_298|Compound:1391-0729|FD-Score:11.60|P-value:1.67E-21 ID:SGTC_299|Compound:1273-0059|FD-Score:-7.27|P-value:1.08E-9 ID:SGTC_308|Compound:4092-1169|FD-Score:6.53|P-value:5.87E-8 ID:SGTC_312|Compound:4092-0653|FD-Score:17.20|P-value:7.53E-45 ID:SGTC_314|Compound:1671-0008|FD-Score:5.71|P-value:1.82E-6 ID:SGTC_320|Compound:4092-0846|FD-Score:8.70|P-value:7.53E-13 ID:SGTC_346|Compound:4513-0042|FD-Score:5.07|P-value:2.05E-5 ID:SGTC_351|Compound:caspofungin|FD-Score:6.73|P-value:2.40E-8 ID:SGTC_352|Compound:k048-0007|FD-Score:4.30|P-value:2.55E-4 ID:SGTC_377|Compound:3970-0964|FD-Score:6.98|P-value:7.37E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:7.44|P-value:7.74E-10 ID:SGTC_386|Compound:1509-0011|FD-Score:4.59|P-value:1.03E-4 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:16.70|P-value:1.88E-42 ID:SGTC_397|Compound:arbidol|FD-Score:8.74|P-value:5.96E-13 ID:SGTC_400|Compound:oxethazaine|FD-Score:24.70|P-value:1.31E-90 ID:SGTC_401|Compound:neomycin|FD-Score:3.96|P-value:7.04E-4 ID:SGTC_420|Compound:mitomycin C|FD-Score:4.55|P-value:1.18E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:6.52|P-value:6.08E-8 ID:SGTC_441|Compound:propafenone|FD-Score:4.88|P-value:3.88E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-14.40|P-value:2.29E-32 ID:SGTC_467|Compound:ro 31-8220|FD-Score:9.92|P-value:3.48E-16 ID:SGTC_469|Compound:w7|FD-Score:7.88|P-value:7.50E-11 ID:SGTC_486|Compound:niguldipine|FD-Score:10.80|P-value:6.38E-19 ID:SGTC_500|Compound:h-89|FD-Score:9.63|P-value:2.35E-15 ID:SGTC_502|Compound:l-744,832|FD-Score:11.00|P-value:1.93E-19 ID:SGTC_515|Compound:4092-1064|FD-Score:9.34|P-value:1.50E-14 ID:SGTC_528|Compound:3492-0019|FD-Score:10.80|P-value:9.85E-19 ID:SGTC_535|Compound:2293-4129|FD-Score:3.86|P-value:9.15E-4 ID:SGTC_547|Compound:1120-0019|FD-Score:3.90|P-value:8.34E-4 ID:SGTC_562|Compound:3772-2733|FD-Score:7.56|P-value:4.18E-10 ID:SGTC_582|Compound:0987-0078|FD-Score:19.90|P-value:2.03E-59 ID:SGTC_598|Compound:3937-0236|FD-Score:4.12|P-value:4.39E-4 ID:SGTC_601|Compound:0986-0029|FD-Score:21.30|P-value:6.59E-68 ID:SGTC_609|Compound:0986-0026|FD-Score:27.20|P-value:2.00E-109 ID:SGTC_614|Compound:0462-0418|FD-Score:11.50|P-value:2.86E-21 ID:SGTC_615|Compound:k087-0205|FD-Score:5.58|P-value:3.13E-6 ID:SGTC_635|Compound:k038-0028|FD-Score:4.72|P-value:6.77E-5 ID:SGTC_637|Compound:1181-0519|FD-Score:8.14|P-value:1.85E-11 ID:SGTC_649|Compound:1123-0311|FD-Score:17.90|P-value:8.68E-49 ID:SGTC_651|Compound:3253-0966|FD-Score:10.10|P-value:1.06E-16 ID:SGTC_658|Compound:3253-0951|FD-Score:20.80|P-value:7.77E-65 ID:SGTC_660|Compound:4031-1742|FD-Score:6.65|P-value:3.35E-8 ID:SGTC_689|Compound:0833-0039|FD-Score:7.88|P-value:7.56E-11 ID:SGTC_701|Compound:4424-0219|FD-Score:18.60|P-value:2.73E-52 ID:SGTC_706|Compound:4262-0057|FD-Score:8.56|P-value:1.74E-12 ID:SGTC_763|Compound:3453-1109|FD-Score:-4.56|P-value:8.20E-5 ID:SGTC_788|Compound:1182-0090|FD-Score:5.20|P-value:1.29E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:5.70|P-value:1.89E-6 ID:SGTC_801|Compound:0866-0028|FD-Score:6.54|P-value:5.54E-8 ID:SGTC_837|Compound:0091-0265|FD-Score:6.30|P-value:1.62E-7 ID:SGTC_841|Compound:0251-0215|FD-Score:5.99|P-value:6.06E-7 ID:SGTC_852|Compound:0418-0143|FD-Score:23.20|P-value:3.22E-80 ID:SGTC_902|Compound:1120-0002|FD-Score:6.76|P-value:2.05E-8 ID:SGTC_905|Compound:2-aminofluorene|FD-Score:4.13|P-value:4.22E-4 ID:SGTC_921|Compound:1561-0023|FD-Score:4.35|P-value:2.20E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:4.07|P-value:5.05E-4 ID:SGTC_956|Compound:1185-0240|FD-Score:6.98|P-value:7.47E-9 ID:SGTC_994|Compound:3910-0338|FD-Score:30.60|P-value:4.63E-138 ID:SGTC_1013|Compound:4112-3890|FD-Score:4.12|P-value:4.43E-4 ID:SGTC_1019|Compound:4262-0212|FD-Score:15.70|P-value:8.62E-38 ID:SGTC_1057|Compound:3448-5381|FD-Score:20.10|P-value:7.54E-61 ID:SGTC_1067|Compound:clotrimazole|FD-Score:5.43|P-value:5.53E-6 ID:SGTC_1072|Compound:oxiconazole|FD-Score:11.30|P-value:1.54E-20 ID:SGTC_1100|Compound:amiodarone|FD-Score:4.69|P-value:7.50E-5 ID:SGTC_1155|Compound:4088-0394|FD-Score:3.94|P-value:7.34E-4 ID:SGTC_1202|Compound:1988-0068|FD-Score:4.40|P-value:1.90E-4 ID:SGTC_1223|Compound:0764-0573|FD-Score:4.04|P-value:5.57E-4 ID:SGTC_1230|Compound:0170-0365|FD-Score:-3.92|P-value:5.74E-4 ID:SGTC_1232|Compound:0279-0259|FD-Score:13.30|P-value:9.67E-28 ID:SGTC_1247|Compound:0448-0043|FD-Score:6.44|P-value:8.83E-8 ID:SGTC_1260|Compound:0700-1617|FD-Score:20.90|P-value:1.47E-65 ID:SGTC_1311|Compound:1190-0148|FD-Score:4.07|P-value:5.06E-4 ID:SGTC_1346|Compound:1488-2224|FD-Score:4.29|P-value:2.63E-4 ID:SGTC_1377|Compound:2944-0135|FD-Score:16.00|P-value:5.20E-39 ID:SGTC_1389|Compound:3405-0187|FD-Score:5.59|P-value:2.96E-6 ID:SGTC_1446|Compound:4239-0190|FD-Score:8.26|P-value:9.75E-12 ID:SGTC_1450|Compound:4112-4260|FD-Score:36.10|P-value:1.39E-191 ID:SGTC_1464|Compound:k208-0027|FD-Score:9.01|P-value:1.16E-13 ID:SGTC_1486|Compound:3970-0793|FD-Score:4.80|P-value:5.23E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:10.50|P-value:7.88E-18 ID:SGTC_1501|Compound:4491-0275|FD-Score:-5.11|P-value:1.23E-5 ID:SGTC_1522|Compound:st012842|FD-Score:4.04|P-value:5.52E-4 ID:SGTC_1529|Compound:apigenin|FD-Score:-3.82|P-value:7.76E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:27.70|P-value:2.39E-113 ID:SGTC_1620|Compound:st003704|FD-Score:7.32|P-value:1.36E-9 ID:SGTC_1621|Compound:st003705|FD-Score:13.90|P-value:3.21E-30 ID:SGTC_1622|Compound:st003707|FD-Score:14.30|P-value:7.83E-32 ID:SGTC_1623|Compound:st003709|FD-Score:13.40|P-value:3.74E-28 ID:SGTC_1624|Compound:st003710|FD-Score:9.19|P-value:3.83E-14 ID:SGTC_1627|Compound:st003713|FD-Score:15.00|P-value:1.12E-34 ID:SGTC_1635|Compound:st007035|FD-Score:6.92|P-value:9.89E-9 ID:SGTC_1656|Compound:st012921|FD-Score:21.20|P-value:2.73E-67 ID:SGTC_1666|Compound:st014829|FD-Score:26.60|P-value:4.24E-105 ID:SGTC_1690|Compound:st023502|FD-Score:10.20|P-value:7.37E-17 ID:SGTC_1712|Compound:st032288|FD-Score:9.21|P-value:3.47E-14 ID:SGTC_1718|Compound:roemerine|FD-Score:4.81|P-value:5.07E-5 ID:SGTC_1728|Compound:st035614|FD-Score:9.53|P-value:4.62E-15 ID:SGTC_1750|Compound:st081859|FD-Score:15.10|P-value:4.74E-35 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:12.30|P-value:7.85E-24 ID:SGTC_1786|Compound:berberine|FD-Score:6.75|P-value:2.16E-8 ID:SGTC_1788|Compound:fluconazole|FD-Score:5.46|P-value:4.91E-6 ID:SGTC_1800|Compound:st050079|FD-Score:4.89|P-value:3.76E-5 ID:SGTC_1801|Compound:st050089|FD-Score:12.00|P-value:5.17E-23 ID:SGTC_1803|Compound:st050068|FD-Score:4.11|P-value:4.49E-4 ID:SGTC_1812|Compound:st052057|FD-Score:10.40|P-value:1.60E-17 ID:SGTC_1826|Compound:st055655|FD-Score:10.40|P-value:1.14E-17 ID:SGTC_2021|Compound:4019055|FD-Score:9.90|P-value:3.98E-16 ID:SGTC_2036|Compound:5160441|FD-Score:15.40|P-value:2.06E-36 ID:SGTC_2038|Compound:4100038|FD-Score:14.40|P-value:4.77E-32 ID:SGTC_2046|Compound:4110841|FD-Score:5.40|P-value:6.15E-6 ID:SGTC_2077|Compound:5212015|FD-Score:5.31|P-value:8.39E-6 ID:SGTC_2110|Compound:5483698|FD-Score:8.37|P-value:5.15E-12 ID:SGTC_2136|Compound:5328288|FD-Score:4.67|P-value:7.84E-5 ID:SGTC_2144|Compound:5628481|FD-Score:12.60|P-value:5.84E-25 ID:SGTC_2211|Compound:7117706|FD-Score:-4.15|P-value:2.91E-4 ID:SGTC_2229|Compound:7354935|FD-Score:4.17|P-value:3.80E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:8.09|P-value:2.43E-11 ID:SGTC_2236|Compound:dapsone|FD-Score:4.54|P-value:1.22E-4 ID:SGTC_2245|Compound:6637752|FD-Score:5.75|P-value:1.59E-6 ID:SGTC_2249|Compound:haloperidol|FD-Score:10.50|P-value:7.28E-18 ID:SGTC_2250|Compound:alverine citrate|FD-Score:9.33|P-value:1.62E-14 ID:SGTC_2300|Compound:7976697|FD-Score:9.67|P-value:1.81E-15 ID:SGTC_2323|Compound:6148992|FD-Score:4.49|P-value:1.42E-4 ID:SGTC_2334|Compound:9017922|FD-Score:3.95|P-value:7.22E-4 ID:SGTC_2358|Compound:9037157|FD-Score:12.00|P-value:5.76E-23 ID:SGTC_2409|Compound:alverine citrate|FD-Score:8.93|P-value:1.97E-13 ID:SGTC_2418|Compound:pentamidine|FD-Score:11.70|P-value:9.60E-22 ID:SGTC_2523|Compound:spermine|FD-Score:27.90|P-value:2.34E-115 ID:SGTC_2533|Compound:agelasine|FD-Score:7.05|P-value:5.14E-9 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:9.41|P-value:9.99E-15 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:5.10|P-value:1.85E-5 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:4.81|P-value:4.99E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:-9.83|P-value:3.14E-16 ID:SGTC_2607|Compound:solasodine|FD-Score:4.98|P-value:2.77E-5 ID:SGTC_2618|Compound:avocadyne|FD-Score:5.40|P-value:6.17E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.31|P-value:1.57E-7 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:8.53|P-value:2.00E-12 ID:SGTC_2688|Compound:kanamycin b|FD-Score:5.36|P-value:7.06E-6 ID:SGTC_2720|Compound:fluspirilene|FD-Score:6.04|P-value:4.90E-7 ID:SGTC_2736|Compound:butenafine|FD-Score:7.26|P-value:1.90E-9 ID:SGTC_2737|Compound:bleomycin|FD-Score:8.52|P-value:2.23E-12 ID:SGTC_2778|Compound:tioconazole|FD-Score:7.88|P-value:7.82E-11 ID:SGTC_2790|Compound:5423970|FD-Score:4.24|P-value:3.06E-4 ID:SGTC_2816|Compound:7982706|FD-Score:4.54|P-value:1.20E-4 ID:SGTC_2896|Compound:9052656|FD-Score:6.58|P-value:4.68E-8 ID:SGTC_2925|Compound:9010536|FD-Score:3.99|P-value:6.47E-4 ID:SGTC_2931|Compound:9014674|FD-Score:-3.89|P-value:6.32E-4 ID:SGTC_2939|Compound:9044578|FD-Score:6.23|P-value:2.15E-7 ID:SGTC_2948|Compound:9070189|FD-Score:6.51|P-value:6.41E-8 ID:SGTC_2959|Compound:9079155|FD-Score:-5.84|P-value:7.21E-7 ID:SGTC_2980|Compound:9014342|FD-Score:4.01|P-value:5.99E-4 ID:SGTC_3018|Compound:9082602|FD-Score:10.50|P-value:5.40E-18 ID:SGTC_3025|Compound:9087895|FD-Score:4.22|P-value:3.22E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:14.90|P-value:4.72E-34 ID:SGTC_3060|Compound:1327-0027|FD-Score:8.23|P-value:1.15E-11 ID:SGTC_3063|Compound:1327-0034|FD-Score:13.50|P-value:1.99E-28 ID:SGTC_3118|Compound:9124250|FD-Score:6.52|P-value:6.09E-8 ID:SGTC_3124|Compound:9127567|FD-Score:5.95|P-value:7.08E-7 ID:SGTC_3126|Compound:9127922|FD-Score:6.80|P-value:1.68E-8 ID:SGTC_3140|Compound:9094243|FD-Score:7.23|P-value:2.16E-9 ID:SGTC_3142|Compound:9086498|FD-Score:-8.77|P-value:2.68E-13 ID:SGTC_3145|Compound:9085516|FD-Score:4.45|P-value:1.61E-4 ID:SGTC_3152|Compound:9099253|FD-Score:5.39|P-value:6.42E-6 ID:SGTC_3203|Compound:9113543|FD-Score:-5.72|P-value:1.19E-6 ID:SGTC_3208|Compound:9114115|FD-Score:7.25|P-value:2.01E-9 ID:SGTC_3212|Compound:9128307|FD-Score:5.71|P-value:1.88E-6 ID:SGTC_3308|Compound:9128332|FD-Score:10.90|P-value:3.08E-19 ID:SGTC_9|Compound:0092-0002|FD-Score:5.18|P-value:1.38E-5 ID:SGTC_29|Compound:0299-0004|FD-Score:8.13|P-value:1.96E-11 ID:SGTC_33|Compound:0986-0033|FD-Score:18.40|P-value:2.43E-51 ID:SGTC_39|Compound:0986-0283|FD-Score:14.40|P-value:6.54E-32 ID:SGTC_40|Compound:0327-0103|FD-Score:10.80|P-value:9.68E-19 ID:SGTC_54|Compound:0159-0055|FD-Score:23.10|P-value:2.49E-79 ID:SGTC_55|Compound:0767-0285|FD-Score:9.59|P-value:3.15E-15 ID:SGTC_57|Compound:miconazole|FD-Score:4.25|P-value:2.99E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:-6.76|P-value:1.28E-8 ID:SGTC_65|Compound:0798-0905|FD-Score:20.40|P-value:2.13E-62 ID:SGTC_68|Compound:0986-0284|FD-Score:19.30|P-value:2.64E-56 ID:SGTC_81|Compound:0411-0046|FD-Score:11.50|P-value:3.86E-21 ID:SGTC_96|Compound:0929-0093|FD-Score:16.20|P-value:3.32E-40 ID:SGTC_103|Compound:0844-0104|FD-Score:-5.13|P-value:1.12E-5 ID:SGTC_117|Compound:lucigenin|FD-Score:13.10|P-value:7.86E-27 ID:SGTC_118|Compound:0083-0097|FD-Score:-4.29|P-value:1.91E-4 ID:SGTC_120|Compound:rhodamine 6G|FD-Score:6.99|P-value:7.06E-9 ID:SGTC_121|Compound:0557-0495|FD-Score:12.10|P-value:2.36E-23 ID:SGTC_127|Compound:0180-0333|FD-Score:7.29|P-value:1.62E-9 ID:SGTC_144|Compound:4161-2749|FD-Score:4.90|P-value:3.71E-5 ID:SGTC_146|Compound:3448-8650|FD-Score:17.50|P-value:2.44E-46 ID:SGTC_178|Compound:4092-0806|FD-Score:19.90|P-value:1.91E-59 ID:SGTC_187|Compound:1488-2104|FD-Score:15.00|P-value:1.17E-34 ID:SGTC_197|Compound:4544-0043|FD-Score:11.70|P-value:1.03E-21 ID:SGTC_201|Compound:4262-0159|FD-Score:7.88|P-value:7.58E-11 ID:SGTC_217|Compound:ketoconazole|FD-Score:5.75|P-value:1.61E-6 ID:SGTC_218|Compound:alverine citrate|FD-Score:7.94|P-value:5.45E-11 ID:SGTC_234|Compound:nsc-17383|FD-Score:5.44|P-value:5.21E-6 ID:SGTC_236|Compound:1509-0011|FD-Score:10.40|P-value:1.21E-17 ID:SGTC_252|Compound:miconazole|FD-Score:4.79|P-value:5.42E-5 ID:SGTC_254|Compound:nsc-64875|FD-Score:4.36|P-value:2.15E-4 ID:SGTC_256|Compound:clotrimazole|FD-Score:7.28|P-value:1.72E-9 ID:SGTC_278|Compound:4092-0821|FD-Score:6.16|P-value:2.96E-7 ID:SGTC_298|Compound:1391-0729|FD-Score:11.60|P-value:1.67E-21 ID:SGTC_299|Compound:1273-0059|FD-Score:-7.27|P-value:1.08E-9 ID:SGTC_308|Compound:4092-1169|FD-Score:6.53|P-value:5.87E-8 ID:SGTC_312|Compound:4092-0653|FD-Score:17.20|P-value:7.53E-45 ID:SGTC_314|Compound:1671-0008|FD-Score:5.71|P-value:1.82E-6 ID:SGTC_320|Compound:4092-0846|FD-Score:8.70|P-value:7.53E-13 ID:SGTC_346|Compound:4513-0042|FD-Score:5.07|P-value:2.05E-5 ID:SGTC_351|Compound:caspofungin|FD-Score:6.73|P-value:2.40E-8 ID:SGTC_352|Compound:k048-0007|FD-Score:4.30|P-value:2.55E-4 ID:SGTC_377|Compound:3970-0964|FD-Score:6.98|P-value:7.37E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:7.44|P-value:7.74E-10 ID:SGTC_386|Compound:1509-0011|FD-Score:4.59|P-value:1.03E-4 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:16.70|P-value:1.88E-42 ID:SGTC_397|Compound:arbidol|FD-Score:8.74|P-value:5.96E-13 ID:SGTC_400|Compound:oxethazaine|FD-Score:24.70|P-value:1.31E-90 ID:SGTC_401|Compound:neomycin|FD-Score:3.96|P-value:7.04E-4 ID:SGTC_420|Compound:mitomycin C|FD-Score:4.55|P-value:1.18E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:6.52|P-value:6.08E-8 ID:SGTC_441|Compound:propafenone|FD-Score:4.88|P-value:3.88E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-14.40|P-value:2.29E-32 ID:SGTC_467|Compound:ro 31-8220|FD-Score:9.92|P-value:3.48E-16 ID:SGTC_469|Compound:w7|FD-Score:7.88|P-value:7.50E-11 ID:SGTC_486|Compound:niguldipine|FD-Score:10.80|P-value:6.38E-19 ID:SGTC_500|Compound:h-89|FD-Score:9.63|P-value:2.35E-15 ID:SGTC_502|Compound:l-744,832|FD-Score:11.00|P-value:1.93E-19 ID:SGTC_515|Compound:4092-1064|FD-Score:9.34|P-value:1.50E-14 ID:SGTC_528|Compound:3492-0019|FD-Score:10.80|P-value:9.85E-19 ID:SGTC_535|Compound:2293-4129|FD-Score:3.86|P-value:9.15E-4 ID:SGTC_547|Compound:1120-0019|FD-Score:3.90|P-value:8.34E-4 ID:SGTC_562|Compound:3772-2733|FD-Score:7.56|P-value:4.18E-10 ID:SGTC_582|Compound:0987-0078|FD-Score:19.90|P-value:2.03E-59 ID:SGTC_598|Compound:3937-0236|FD-Score:4.12|P-value:4.39E-4 ID:SGTC_601|Compound:0986-0029|FD-Score:21.30|P-value:6.59E-68 ID:SGTC_609|Compound:0986-0026|FD-Score:27.20|P-value:2.00E-109 ID:SGTC_614|Compound:0462-0418|FD-Score:11.50|P-value:2.86E-21 ID:SGTC_615|Compound:k087-0205|FD-Score:5.58|P-value:3.13E-6 ID:SGTC_635|Compound:k038-0028|FD-Score:4.72|P-value:6.77E-5 ID:SGTC_637|Compound:1181-0519|FD-Score:8.14|P-value:1.85E-11 ID:SGTC_649|Compound:1123-0311|FD-Score:17.90|P-value:8.68E-49 ID:SGTC_651|Compound:3253-0966|FD-Score:10.10|P-value:1.06E-16 ID:SGTC_658|Compound:3253-0951|FD-Score:20.80|P-value:7.77E-65 ID:SGTC_660|Compound:4031-1742|FD-Score:6.65|P-value:3.35E-8 ID:SGTC_689|Compound:0833-0039|FD-Score:7.88|P-value:7.56E-11 ID:SGTC_701|Compound:4424-0219|FD-Score:18.60|P-value:2.73E-52 ID:SGTC_706|Compound:4262-0057|FD-Score:8.56|P-value:1.74E-12 ID:SGTC_763|Compound:3453-1109|FD-Score:-4.56|P-value:8.20E-5 ID:SGTC_788|Compound:1182-0090|FD-Score:5.20|P-value:1.29E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:5.70|P-value:1.89E-6 ID:SGTC_801|Compound:0866-0028|FD-Score:6.54|P-value:5.54E-8 ID:SGTC_837|Compound:0091-0265|FD-Score:6.30|P-value:1.62E-7 ID:SGTC_841|Compound:0251-0215|FD-Score:5.99|P-value:6.06E-7 ID:SGTC_852|Compound:0418-0143|FD-Score:23.20|P-value:3.22E-80 ID:SGTC_902|Compound:1120-0002|FD-Score:6.76|P-value:2.05E-8 ID:SGTC_905|Compound:2-aminofluorene|FD-Score:4.13|P-value:4.22E-4 ID:SGTC_921|Compound:1561-0023|FD-Score:4.35|P-value:2.20E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:4.07|P-value:5.05E-4 ID:SGTC_956|Compound:1185-0240|FD-Score:6.98|P-value:7.47E-9 ID:SGTC_994|Compound:3910-0338|FD-Score:30.60|P-value:4.63E-138 ID:SGTC_1013|Compound:4112-3890|FD-Score:4.12|P-value:4.43E-4 ID:SGTC_1019|Compound:4262-0212|FD-Score:15.70|P-value:8.62E-38 ID:SGTC_1057|Compound:3448-5381|FD-Score:20.10|P-value:7.54E-61 ID:SGTC_1067|Compound:clotrimazole|FD-Score:5.43|P-value:5.53E-6 ID:SGTC_1072|Compound:oxiconazole|FD-Score:11.30|P-value:1.54E-20 ID:SGTC_1100|Compound:amiodarone|FD-Score:4.69|P-value:7.50E-5 ID:SGTC_1155|Compound:4088-0394|FD-Score:3.94|P-value:7.34E-4 ID:SGTC_1202|Compound:1988-0068|FD-Score:4.40|P-value:1.90E-4 ID:SGTC_1223|Compound:0764-0573|FD-Score:4.04|P-value:5.57E-4 ID:SGTC_1230|Compound:0170-0365|FD-Score:-3.92|P-value:5.74E-4 ID:SGTC_1232|Compound:0279-0259|FD-Score:13.30|P-value:9.67E-28 ID:SGTC_1247|Compound:0448-0043|FD-Score:6.44|P-value:8.83E-8 ID:SGTC_1260|Compound:0700-1617|FD-Score:20.90|P-value:1.47E-65 ID:SGTC_1311|Compound:1190-0148|FD-Score:4.07|P-value:5.06E-4 ID:SGTC_1346|Compound:1488-2224|FD-Score:4.29|P-value:2.63E-4 ID:SGTC_1377|Compound:2944-0135|FD-Score:16.00|P-value:5.20E-39 ID:SGTC_1389|Compound:3405-0187|FD-Score:5.59|P-value:2.96E-6 ID:SGTC_1446|Compound:4239-0190|FD-Score:8.26|P-value:9.75E-12 ID:SGTC_1450|Compound:4112-4260|FD-Score:36.10|P-value:1.39E-191 ID:SGTC_1464|Compound:k208-0027|FD-Score:9.01|P-value:1.16E-13 ID:SGTC_1486|Compound:3970-0793|FD-Score:4.80|P-value:5.23E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:10.50|P-value:7.88E-18 ID:SGTC_1501|Compound:4491-0275|FD-Score:-5.11|P-value:1.23E-5 ID:SGTC_1522|Compound:st012842|FD-Score:4.04|P-value:5.52E-4 ID:SGTC_1529|Compound:apigenin|FD-Score:-3.82|P-value:7.76E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:27.70|P-value:2.39E-113 ID:SGTC_1620|Compound:st003704|FD-Score:7.32|P-value:1.36E-9 ID:SGTC_1621|Compound:st003705|FD-Score:13.90|P-value:3.21E-30 ID:SGTC_1622|Compound:st003707|FD-Score:14.30|P-value:7.83E-32 ID:SGTC_1623|Compound:st003709|FD-Score:13.40|P-value:3.74E-28 ID:SGTC_1624|Compound:st003710|FD-Score:9.19|P-value:3.83E-14 ID:SGTC_1627|Compound:st003713|FD-Score:15.00|P-value:1.12E-34 ID:SGTC_1635|Compound:st007035|FD-Score:6.92|P-value:9.89E-9 ID:SGTC_1656|Compound:st012921|FD-Score:21.20|P-value:2.73E-67 ID:SGTC_1666|Compound:st014829|FD-Score:26.60|P-value:4.24E-105 ID:SGTC_1690|Compound:st023502|FD-Score:10.20|P-value:7.37E-17 ID:SGTC_1712|Compound:st032288|FD-Score:9.21|P-value:3.47E-14 ID:SGTC_1718|Compound:roemerine|FD-Score:4.81|P-value:5.07E-5 ID:SGTC_1728|Compound:st035614|FD-Score:9.53|P-value:4.62E-15 ID:SGTC_1750|Compound:st081859|FD-Score:15.10|P-value:4.74E-35 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:12.30|P-value:7.85E-24 ID:SGTC_1786|Compound:berberine|FD-Score:6.75|P-value:2.16E-8 ID:SGTC_1788|Compound:fluconazole|FD-Score:5.46|P-value:4.91E-6 ID:SGTC_1800|Compound:st050079|FD-Score:4.89|P-value:3.76E-5 ID:SGTC_1801|Compound:st050089|FD-Score:12.00|P-value:5.17E-23 ID:SGTC_1803|Compound:st050068|FD-Score:4.11|P-value:4.49E-4 ID:SGTC_1812|Compound:st052057|FD-Score:10.40|P-value:1.60E-17 ID:SGTC_1826|Compound:st055655|FD-Score:10.40|P-value:1.14E-17 ID:SGTC_2021|Compound:4019055|FD-Score:9.90|P-value:3.98E-16 ID:SGTC_2036|Compound:5160441|FD-Score:15.40|P-value:2.06E-36 ID:SGTC_2038|Compound:4100038|FD-Score:14.40|P-value:4.77E-32 ID:SGTC_2046|Compound:4110841|FD-Score:5.40|P-value:6.15E-6 ID:SGTC_2077|Compound:5212015|FD-Score:5.31|P-value:8.39E-6 ID:SGTC_2110|Compound:5483698|FD-Score:8.37|P-value:5.15E-12 ID:SGTC_2136|Compound:5328288|FD-Score:4.67|P-value:7.84E-5 ID:SGTC_2144|Compound:5628481|FD-Score:12.60|P-value:5.84E-25 ID:SGTC_2211|Compound:7117706|FD-Score:-4.15|P-value:2.91E-4 ID:SGTC_2229|Compound:7354935|FD-Score:4.17|P-value:3.80E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:8.09|P-value:2.43E-11 ID:SGTC_2236|Compound:dapsone|FD-Score:4.54|P-value:1.22E-4 ID:SGTC_2245|Compound:6637752|FD-Score:5.75|P-value:1.59E-6 ID:SGTC_2249|Compound:haloperidol|FD-Score:10.50|P-value:7.28E-18 ID:SGTC_2250|Compound:alverine citrate|FD-Score:9.33|P-value:1.62E-14 ID:SGTC_2300|Compound:7976697|FD-Score:9.67|P-value:1.81E-15 ID:SGTC_2323|Compound:6148992|FD-Score:4.49|P-value:1.42E-4 ID:SGTC_2334|Compound:9017922|FD-Score:3.95|P-value:7.22E-4 ID:SGTC_2358|Compound:9037157|FD-Score:12.00|P-value:5.76E-23 ID:SGTC_2409|Compound:alverine citrate|FD-Score:8.93|P-value:1.97E-13 ID:SGTC_2418|Compound:pentamidine|FD-Score:11.70|P-value:9.60E-22 ID:SGTC_2523|Compound:spermine|FD-Score:27.90|P-value:2.34E-115 ID:SGTC_2533|Compound:agelasine|FD-Score:7.05|P-value:5.14E-9 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:9.41|P-value:9.99E-15 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:5.10|P-value:1.85E-5 ID:SGTC_2578|Compound:7,8-dihydroxyflavone|FD-Score:4.81|P-value:4.99E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:-9.83|P-value:3.14E-16 ID:SGTC_2607|Compound:solasodine|FD-Score:4.98|P-value:2.77E-5 ID:SGTC_2618|Compound:avocadyne|FD-Score:5.40|P-value:6.17E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.31|P-value:1.57E-7 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:8.53|P-value:2.00E-12 ID:SGTC_2688|Compound:kanamycin b|FD-Score:5.36|P-value:7.06E-6 ID:SGTC_2720|Compound:fluspirilene|FD-Score:6.04|P-value:4.90E-7 ID:SGTC_2736|Compound:butenafine|FD-Score:7.26|P-value:1.90E-9 ID:SGTC_2737|Compound:bleomycin|FD-Score:8.52|P-value:2.23E-12 ID:SGTC_2778|Compound:tioconazole|FD-Score:7.88|P-value:7.82E-11 ID:SGTC_2790|Compound:5423970|FD-Score:4.24|P-value:3.06E-4 ID:SGTC_2816|Compound:7982706|FD-Score:4.54|P-value:1.20E-4 ID:SGTC_2896|Compound:9052656|FD-Score:6.58|P-value:4.68E-8 ID:SGTC_2925|Compound:9010536|FD-Score:3.99|P-value:6.47E-4 ID:SGTC_2931|Compound:9014674|FD-Score:-3.89|P-value:6.32E-4 ID:SGTC_2939|Compound:9044578|FD-Score:6.23|P-value:2.15E-7 ID:SGTC_2948|Compound:9070189|FD-Score:6.51|P-value:6.41E-8 ID:SGTC_2959|Compound:9079155|FD-Score:-5.84|P-value:7.21E-7 ID:SGTC_2980|Compound:9014342|FD-Score:4.01|P-value:5.99E-4 ID:SGTC_3018|Compound:9082602|FD-Score:10.50|P-value:5.40E-18 ID:SGTC_3025|Compound:9087895|FD-Score:4.22|P-value:3.22E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:14.90|P-value:4.72E-34 ID:SGTC_3060|Compound:1327-0027|FD-Score:8.23|P-value:1.15E-11 ID:SGTC_3063|Compound:1327-0034|FD-Score:13.50|P-value:1.99E-28 ID:SGTC_3118|Compound:9124250|FD-Score:6.52|P-value:6.09E-8 ID:SGTC_3124|Compound:9127567|FD-Score:5.95|P-value:7.08E-7 ID:SGTC_3126|Compound:9127922|FD-Score:6.80|P-value:1.68E-8 ID:SGTC_3140|Compound:9094243|FD-Score:7.23|P-value:2.16E-9 ID:SGTC_3142|Compound:9086498|FD-Score:-8.77|P-value:2.68E-13 ID:SGTC_3145|Compound:9085516|FD-Score:4.45|P-value:1.61E-4 ID:SGTC_3152|Compound:9099253|FD-Score:5.39|P-value:6.42E-6 ID:SGTC_3203|Compound:9113543|FD-Score:-5.72|P-value:1.19E-6 ID:SGTC_3208|Compound:9114115|FD-Score:7.25|P-value:2.01E-9 ID:SGTC_3212|Compound:9128307|FD-Score:5.71|P-value:1.88E-6 ID:SGTC_3308|Compound:9128332|FD-Score:10.90|P-value:3.08E-19

Top fitness defect scores for YIL154C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1450 4112-4260 36.10 37.6 µM 1.39E-191 calcium & mitochondrial duress 1 4.57E-286
2 SGTC_994 3910-0338 30.60 138.0 µM 4.63E-138 calcium & mitochondrial duress 1 5.97E-206
3 SGTC_2523 spermine 27.90 47.7 µM 2.34E-115 calcium & mitochondrial duress 1 5.79E-172
4 SGTC_1597 7-benzyloxygramine 27.70 47.5 µM 2.39E-113 calcium & mitochondrial duress 1 5.89E-169
5 SGTC_609 0986-0026 27.20 86.3 µM 2.00E-109 calcium & mitochondrial duress 1 4.38E-163
6 SGTC_1666 st014829 26.60 29.0 µM 4.24E-105 calcium & mitochondrial duress 1 1.31E-156
7 SGTC_400 oxethazaine 24.70 37.5 µM 1.31E-90 calcium & mitochondrial duress 1 6.47E-135
8 SGTC_852 0418-0143 23.20 439.0 µM 3.22E-80 calcium & mitochondrial duress 2 2.32E-119
9 SGTC_54 0159-0055 23.10 9.0 µM 2.49E-79 ERG2 2 4.97E-118
10 SGTC_601 0986-0029 21.30 62.9 µM 6.59E-68 calcium & mitochondrial duress 1 6.28E-101
11 SGTC_1656 st012921 21.20 11.0 µM 2.73E-67 2 5.27E-100
12 SGTC_1260 0700-1617 20.90 7.8 µM 1.47E-65 calcium & mitochondrial duress 1 2.07E-97
13 SGTC_658 3253-0951 20.80 102.0 µM 7.77E-65 calcium & mitochondrial duress 1 2.49E-96
14 SGTC_65 0798-0905 20.40 35.0 µM 2.13E-62 calcium & mitochondrial duress 1 1.11E-92
15 SGTC_1057 3448-5381 20.10 134.0 µM 7.54E-61 calcium & mitochondrial duress 1 2.32E-90
16 SGTC_178 4092-0806 19.90 87.5 µM 1.91E-59 ergosterol depletion effects on membrane 2 2.94E-88
17 SGTC_582 0987-0078 19.90 156.0 µM 2.03E-59 calcium & mitochondrial duress 2 3.21E-88
18 SGTC_68 0986-0284 19.30 82.8 µM 2.64E-56 1 1.48E-83
19 SGTC_701 4424-0219 18.60 185.0 µM 2.73E-52 calcium & mitochondrial duress 1 1.52E-77
20 SGTC_33 0986-0033 18.40 35.8 µM 2.43E-51 calcium & mitochondrial duress 1 3.99E-76

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.422 9.41E-145 YGR285C ZUO1 hom Ribosome-associated chaperone, functions in ribosome biogenesis and, in partnership with Ssz1p and SSb1/2, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p
0.376 1.59E-112 YJL129C TRK1 hom Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation; TRK1 has a paralog, TRK2, that arose from the whole genome duplication
0.334 3.64E-88 YML007C-A_p YML007C-A_p hom Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria
0.323 3.74E-82 YBR109C CMD1 het Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin
0.323 1.00E-81 YJL165C HAL5 hom Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication
0.314 2.10E-77 YKL212W SAC1 hom Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism
0.312 2.11E-76 YMR202W ERG2 hom C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
0.311 7.06E-76 YIL105C SLM1 hom Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex; protein abundance increases in response to DNA replication stress; SLM1 has a paralog, SLM2, that arose from the whole genome duplication
0.263 4.38E-54 YKL135C APL2 hom Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress
0.263 5.20E-54 YPL145C KES1 hom One of seven members of the yeast oxysterol binding protein family; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; KES1 has a paralog, HES1, that arose from the whole genome duplication
0.246 1.95E-47 YMR071C TVP18 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments
0.246 3.04E-47 YKL126W YPK1 hom Serine/threonine protein kinase; phosphorylates and downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p (inhibitors of serine:palmitoyl-coenzyme A transferase) by phosphorylation in response to compromised sphingolipid synthesis; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK; YPK1 has a paralog, YPK2, that arose from the whole genome duplication
0.242 8.01E-46 YJL207C LAA1 hom AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene
0.239 1.14E-44 YHR064C SSZ1 hom Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP
0.234 5.77E-43 YFL034W_p YFL034W_p hom Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk