YIR023W / DAL81

Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism

Zygosity: Homozygous strain
fixedexpanded
Profile for YIR023W / DAL81

Click on Significant Values for Screen Details ID:SGTC_79|Compound:0052-0007|FD-Score:8.29|P-value:2.12E-6 ID:SGTC_87|Compound:0100-0052|FD-Score:10.10|P-value:1.04E-8 ID:SGTC_109|Compound:0132-0036|FD-Score:5.81|P-value:6.57E-4 ID:SGTC_110|Compound:0850-0284|FD-Score:6.32|P-value:2.34E-4 ID:SGTC_126|Compound:0417-1624|FD-Score:5.99|P-value:4.69E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:10.10|P-value:1.05E-8 ID:SGTC_161|Compound:4065-0411|FD-Score:16.60|P-value:1.05E-20 ID:SGTC_163|Compound:1327-0036|FD-Score:9.86|P-value:2.10E-8 ID:SGTC_180|Compound:1486-1293|FD-Score:7.14|P-value:3.78E-5 ID:SGTC_253|Compound:dyclonine|FD-Score:13.20|P-value:8.55E-14 ID:SGTC_279|Compound:1273-0055|FD-Score:5.89|P-value:5.69E-4 ID:SGTC_283|Compound:0987-0079|FD-Score:7.31|P-value:2.57E-5 ID:SGTC_325|Compound:2810-4341|FD-Score:12.20|P-value:5.85E-12 ID:SGTC_333|Compound:3486-0131|FD-Score:5.61|P-value:9.77E-4 ID:SGTC_337|Compound:1315-0038|FD-Score:25.50|P-value:2.52E-46 ID:SGTC_343|Compound:4130-2827|FD-Score:7.22|P-value:3.12E-5 ID:SGTC_375|Compound:3970-0961|FD-Score:7.41|P-value:1.99E-5 ID:SGTC_389|Compound:tpck|FD-Score:11.00|P-value:5.41E-10 ID:SGTC_394|Compound:menadione|FD-Score:6.21|P-value:2.94E-4 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:5.77|P-value:7.18E-4 ID:SGTC_413|Compound:propylparaben|FD-Score:8.46|P-value:1.33E-6 ID:SGTC_425|Compound:3825-7017|FD-Score:6.24|P-value:2.78E-4 ID:SGTC_438|Compound:sphingosine|FD-Score:-6.16|P-value:2.26E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:6.48|P-value:1.66E-4 ID:SGTC_486|Compound:niguldipine|FD-Score:35.50|P-value:5.99E-88 ID:SGTC_505|Compound:gw-5074|FD-Score:6.20|P-value:3.04E-4 ID:SGTC_517|Compound:1365-0151|FD-Score:8.42|P-value:1.46E-6 ID:SGTC_534|Compound:k292-0788|FD-Score:5.99|P-value:4.63E-4 ID:SGTC_556|Compound:4058-0063|FD-Score:8.78|P-value:5.40E-7 ID:SGTC_562|Compound:3772-2733|FD-Score:11.60|P-value:6.14E-11 ID:SGTC_563|Compound:tetrahydrosecaminediol|FD-Score:9.37|P-value:9.57E-8 ID:SGTC_569|Compound:4130-2812|FD-Score:19.10|P-value:8.19E-27 ID:SGTC_581|Compound:0958-0271|FD-Score:17.80|P-value:1.49E-23 ID:SGTC_592|Compound:k241-0073|FD-Score:11.90|P-value:1.59E-11 ID:SGTC_603|Compound:3794-0023|FD-Score:7.60|P-value:1.24E-5 ID:SGTC_605|Compound:1315-0399|FD-Score:9.65|P-value:4.01E-8 ID:SGTC_639|Compound:0833-0042|FD-Score:13.80|P-value:7.00E-15 ID:SGTC_650|Compound:1328-0195|FD-Score:5.73|P-value:7.70E-4 ID:SGTC_676|Compound:falcarinol|FD-Score:9.80|P-value:2.52E-8 ID:SGTC_683|Compound:panaxydol|FD-Score:6.10|P-value:3.70E-4 ID:SGTC_700|Compound:3453-2283|FD-Score:18.30|P-value:8.31E-25 ID:SGTC_702|Compound:1488-0190|FD-Score:6.28|P-value:2.57E-4 ID:SGTC_744|Compound:1594-0068|FD-Score:10.20|P-value:6.33E-9 ID:SGTC_749|Compound:1000-0129|FD-Score:7.12|P-value:3.97E-5 ID:SGTC_781|Compound:4335-2806|FD-Score:9.84|P-value:2.24E-8 ID:SGTC_823|Compound:0417-1665|FD-Score:15.30|P-value:6.43E-18 ID:SGTC_825|Compound:1988-2224|FD-Score:10.30|P-value:4.73E-9 ID:SGTC_845|Compound:0330-0138|FD-Score:9.92|P-value:1.76E-8 ID:SGTC_849|Compound:0386-0493|FD-Score:9.37|P-value:9.56E-8 ID:SGTC_860|Compound:0443-0016|FD-Score:7.51|P-value:1.56E-5 ID:SGTC_867|Compound:0518-0118|FD-Score:12.60|P-value:9.49E-13 ID:SGTC_870|Compound:0573-2213|FD-Score:7.10|P-value:4.19E-5 ID:SGTC_872|Compound:0588-0139|FD-Score:7.27|P-value:2.79E-5 ID:SGTC_878|Compound:0828-0289|FD-Score:13.20|P-value:1.08E-13 ID:SGTC_933|Compound:2914-0560|FD-Score:14.40|P-value:4.12E-16 ID:SGTC_942|Compound:3253-1115|FD-Score:5.77|P-value:7.16E-4 ID:SGTC_974|Compound:1326-0144|FD-Score:14.20|P-value:1.25E-15 ID:SGTC_990|Compound:3985-0011|FD-Score:26.40|P-value:1.31E-49 ID:SGTC_1013|Compound:4112-3890|FD-Score:6.43|P-value:1.87E-4 ID:SGTC_1056|Compound:3448-1962|FD-Score:20.50|P-value:1.57E-30 ID:SGTC_1058|Compound:3448-5425|FD-Score:21.50|P-value:1.12E-33 ID:SGTC_1063|Compound:disulfiram|FD-Score:-5.90|P-value:3.94E-4 ID:SGTC_1100|Compound:amiodarone|FD-Score:6.19|P-value:3.09E-4 ID:SGTC_1123|Compound:mangostin|FD-Score:7.30|P-value:2.59E-5 ID:SGTC_1130|Compound:3454-2858|FD-Score:6.29|P-value:2.52E-4 ID:SGTC_1173|Compound:0443-0020|FD-Score:11.20|P-value:2.42E-10 ID:SGTC_1181|Compound:1222-0449|FD-Score:14.90|P-value:4.51E-17 ID:SGTC_1187|Compound:1391-0724|FD-Score:12.20|P-value:6.31E-12 ID:SGTC_1194|Compound:1488-0194|FD-Score:6.28|P-value:2.54E-4 ID:SGTC_1237|Compound:0330-0133|FD-Score:8.42|P-value:1.49E-6 ID:SGTC_1245|Compound:0418-0076|FD-Score:5.67|P-value:8.76E-4 ID:SGTC_1263|Compound:0774-1208|FD-Score:5.74|P-value:7.56E-4 ID:SGTC_1352|Compound:1496-0991|FD-Score:7.34|P-value:2.34E-5 ID:SGTC_1360|Compound:1598-0022|FD-Score:5.79|P-value:6.83E-4 ID:SGTC_1369|Compound:1866-0067|FD-Score:6.69|P-value:1.05E-4 ID:SGTC_1462|Compound:k081-0014|FD-Score:-12.00|P-value:6.36E-12 ID:SGTC_1463|Compound:k081-0032|FD-Score:-11.00|P-value:2.74E-10 ID:SGTC_1474|Compound:0330-0125|FD-Score:6.17|P-value:3.24E-4 ID:SGTC_1478|Compound:0453-0656|FD-Score:6.22|P-value:2.89E-4 ID:SGTC_1508|Compound:1080-0625|FD-Score:9.23|P-value:1.48E-7 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:6.10|P-value:3.70E-4 ID:SGTC_1599|Compound:8-chlro-1-tetrahydronorharmanone|FD-Score:9.20|P-value:1.61E-7 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:7.18|P-value:3.47E-5 ID:SGTC_1614|Compound:st002383|FD-Score:6.02|P-value:4.33E-4 ID:SGTC_1629|Compound:st005085|FD-Score:7.22|P-value:3.16E-5 ID:SGTC_1678|Compound:st019265|FD-Score:8.17|P-value:2.92E-6 ID:SGTC_1699|Compound:st031318|FD-Score:7.17|P-value:3.52E-5 ID:SGTC_1710|Compound:st031758|FD-Score:6.86|P-value:7.25E-5 ID:SGTC_1726|Compound:st035556|FD-Score:10.60|P-value:2.04E-9 ID:SGTC_1759|Compound:st043059|FD-Score:14.90|P-value:4.47E-17 ID:SGTC_1764|Compound:st044502|FD-Score:8.03|P-value:4.21E-6 ID:SGTC_1819|Compound:st053448|FD-Score:6.21|P-value:2.99E-4 ID:SGTC_1824|Compound:st053723|FD-Score:14.20|P-value:1.01E-15 ID:SGTC_1853|Compound:st056710|FD-Score:10.30|P-value:5.77E-9 ID:SGTC_1854|Compound:st056233|FD-Score:7.07|P-value:4.46E-5 ID:SGTC_1864|Compound:st057645|FD-Score:7.30|P-value:2.61E-5 ID:SGTC_1865|Compound:st057639|FD-Score:6.61|P-value:1.28E-4 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:6.37|P-value:2.13E-4 ID:SGTC_1892|Compound:st058411|FD-Score:6.76|P-value:9.18E-5 ID:SGTC_1904|Compound:st060225|FD-Score:-5.68|P-value:6.10E-4 ID:SGTC_1909|Compound:st060837|FD-Score:8.25|P-value:2.36E-6 ID:SGTC_1915|Compound:st067105|FD-Score:7.57|P-value:1.35E-5 ID:SGTC_1953|Compound:st076800|FD-Score:8.12|P-value:3.33E-6 ID:SGTC_1958|Compound:st076513|FD-Score:10.60|P-value:1.80E-9 ID:SGTC_1970|Compound:st070122|FD-Score:5.94|P-value:5.10E-4 ID:SGTC_1975|Compound:st070967|FD-Score:8.16|P-value:2.93E-6 ID:SGTC_2055|Compound:5235184|FD-Score:5.93|P-value:5.21E-4 ID:SGTC_2059|Compound:5238311|FD-Score:7.40|P-value:2.07E-5 ID:SGTC_2090|Compound:5301565|FD-Score:17.70|P-value:2.46E-23 ID:SGTC_2092|Compound:5303694|FD-Score:8.07|P-value:3.78E-6 ID:SGTC_2093|Compound:5331342|FD-Score:21.00|P-value:3.41E-32 ID:SGTC_2094|Compound:5332512|FD-Score:6.61|P-value:1.25E-4 ID:SGTC_2137|Compound:5261020|FD-Score:15.50|P-value:2.67E-18 ID:SGTC_2197|Compound:6588183|FD-Score:5.66|P-value:8.83E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:10.00|P-value:1.25E-8 ID:SGTC_2233|Compound:sulbentine|FD-Score:6.16|P-value:3.29E-4 ID:SGTC_2254|Compound:7938975|FD-Score:12.30|P-value:3.37E-12 ID:SGTC_2255|Compound:7941087|FD-Score:11.10|P-value:2.90E-10 ID:SGTC_2296|Compound:7971656|FD-Score:9.51|P-value:6.21E-8 ID:SGTC_2322|Compound:7413319|FD-Score:9.33|P-value:1.09E-7 ID:SGTC_2335|Compound:9018011|FD-Score:5.67|P-value:8.61E-4 ID:SGTC_2396|Compound:5342950|FD-Score:9.33|P-value:1.07E-7 ID:SGTC_2413|Compound:inermin|FD-Score:5.75|P-value:7.43E-4 ID:SGTC_2424|Compound:5537928|FD-Score:6.74|P-value:9.45E-5 ID:SGTC_2430|Compound:5571206|FD-Score:6.15|P-value:3.34E-4 ID:SGTC_2444|Compound:5485484|FD-Score:8.02|P-value:4.27E-6 ID:SGTC_2447|Compound:5741742|FD-Score:-6.32|P-value:1.62E-4 ID:SGTC_2460|Compound:5552655|FD-Score:41.60|P-value:3.37E-120 ID:SGTC_2461|Compound:5755302|FD-Score:12.80|P-value:5.39E-13 ID:SGTC_2462|Compound:5162487|FD-Score:5.82|P-value:6.49E-4 ID:SGTC_2498|Compound:4'-Methoxychalcone|FD-Score:7.41|P-value:1.99E-5 ID:SGTC_2499|Compound:avocadenofuran|FD-Score:7.12|P-value:4.00E-5 ID:SGTC_2557|Compound:derrustone|FD-Score:6.61|P-value:1.28E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:21.00|P-value:4.58E-32 ID:SGTC_2574|Compound:2',4'-dihydroxychalcone|FD-Score:12.80|P-value:5.26E-13 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:12.10|P-value:7.68E-12 ID:SGTC_2579|Compound:2',5'-dihydroxy-4-methoxychalcone|FD-Score:10.50|P-value:2.57E-9 ID:SGTC_2581|Compound:avocatin a|FD-Score:5.92|P-value:5.39E-4 ID:SGTC_2594|Compound:a-mangostin|FD-Score:6.52|P-value:1.54E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:6.65|P-value:1.17E-4 ID:SGTC_2618|Compound:avocadyne|FD-Score:16.00|P-value:2.04E-19 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:10.90|P-value:7.36E-10 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.48|P-value:1.66E-4 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:6.12|P-value:3.59E-4 ID:SGTC_2660|Compound:2',4'-dihydroxychalcone|FD-Score:6.33|P-value:2.30E-4 ID:SGTC_2680|Compound:butyl paraben|FD-Score:7.30|P-value:2.62E-5 ID:SGTC_2683|Compound:piperine|FD-Score:9.81|P-value:2.43E-8 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.21|P-value:3.24E-5 ID:SGTC_2696|Compound:st077691|FD-Score:5.72|P-value:7.87E-4 ID:SGTC_2701|Compound:st077767|FD-Score:9.68|P-value:3.67E-8 ID:SGTC_2774|Compound:tamoxifen|FD-Score:-5.91|P-value:3.82E-4 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:-6.73|P-value:6.63E-5 ID:SGTC_2776|Compound:terbinafine|FD-Score:-7.73|P-value:5.86E-6 ID:SGTC_2833|Compound:9001315|FD-Score:18.80|P-value:3.45E-26 ID:SGTC_2841|Compound:9004761|FD-Score:11.90|P-value:2.04E-11 ID:SGTC_2845|Compound:9003024|FD-Score:39.30|P-value:9.99E-108 ID:SGTC_2852|Compound:9023854|FD-Score:7.29|P-value:2.68E-5 ID:SGTC_2855|Compound:9016525|FD-Score:5.62|P-value:9.58E-4 ID:SGTC_2921|Compound:7974240|FD-Score:8.76|P-value:5.79E-7 ID:SGTC_2924|Compound:9010168|FD-Score:6.13|P-value:3.52E-4 ID:SGTC_2932|Compound:9016711|FD-Score:14.60|P-value:1.90E-16 ID:SGTC_2939|Compound:9044578|FD-Score:6.26|P-value:2.66E-4 ID:SGTC_2976|Compound:9009005|FD-Score:14.80|P-value:8.35E-17 ID:SGTC_2980|Compound:9014342|FD-Score:15.10|P-value:2.22E-17 ID:SGTC_2982|Compound:9019404|FD-Score:9.19|P-value:1.64E-7 ID:SGTC_2999|Compound:9069765|FD-Score:7.31|P-value:2.57E-5 ID:SGTC_3025|Compound:9087895|FD-Score:6.45|P-value:1.79E-4 ID:SGTC_3034|Compound:9090421|FD-Score:6.89|P-value:6.78E-5 ID:SGTC_3065|Compound:9113888|FD-Score:6.83|P-value:7.67E-5 ID:SGTC_3088|Compound:9117578|FD-Score:7.17|P-value:3.57E-5 ID:SGTC_3100|Compound:9120536|FD-Score:5.94|P-value:5.10E-4 ID:SGTC_3101|Compound:9120531|FD-Score:7.58|P-value:1.31E-5 ID:SGTC_3131|Compound:9127911|FD-Score:6.60|P-value:1.30E-4 ID:SGTC_3143|Compound:9086658|FD-Score:6.79|P-value:8.54E-5 ID:SGTC_3155|Compound:9099265|FD-Score:6.04|P-value:4.23E-4 ID:SGTC_3167|Compound:9103034|FD-Score:8.56|P-value:1.00E-6 ID:SGTC_3168|Compound:9103419|FD-Score:6.72|P-value:1.00E-4 ID:SGTC_3174|Compound:9107204|FD-Score:9.30|P-value:1.17E-7 ID:SGTC_3211|Compound:9128781|FD-Score:6.94|P-value:5.99E-5 ID:SGTC_3225|Compound:9130819|FD-Score:13.70|P-value:1.12E-14 ID:SGTC_3228|Compound:9131799|FD-Score:12.50|P-value:1.91E-12 ID:SGTC_3235|Compound:9132602|FD-Score:8.94|P-value:3.38E-7 ID:SGTC_3237|Compound:9133362|FD-Score:15.20|P-value:1.37E-17 ID:SGTC_3292|Compound:9120825|FD-Score:6.09|P-value:3.80E-4 ID:SGTC_3303|Compound:9125618|FD-Score:14.80|P-value:8.92E-17 ID:SGTC_3330|Compound:9141424|FD-Score:12.70|P-value:8.59E-13 ID:SGTC_79|Compound:0052-0007|FD-Score:8.29|P-value:2.12E-6 ID:SGTC_87|Compound:0100-0052|FD-Score:10.10|P-value:1.04E-8 ID:SGTC_109|Compound:0132-0036|FD-Score:5.81|P-value:6.57E-4 ID:SGTC_110|Compound:0850-0284|FD-Score:6.32|P-value:2.34E-4 ID:SGTC_126|Compound:0417-1624|FD-Score:5.99|P-value:4.69E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:10.10|P-value:1.05E-8 ID:SGTC_161|Compound:4065-0411|FD-Score:16.60|P-value:1.05E-20 ID:SGTC_163|Compound:1327-0036|FD-Score:9.86|P-value:2.10E-8 ID:SGTC_180|Compound:1486-1293|FD-Score:7.14|P-value:3.78E-5 ID:SGTC_253|Compound:dyclonine|FD-Score:13.20|P-value:8.55E-14 ID:SGTC_279|Compound:1273-0055|FD-Score:5.89|P-value:5.69E-4 ID:SGTC_283|Compound:0987-0079|FD-Score:7.31|P-value:2.57E-5 ID:SGTC_325|Compound:2810-4341|FD-Score:12.20|P-value:5.85E-12 ID:SGTC_333|Compound:3486-0131|FD-Score:5.61|P-value:9.77E-4 ID:SGTC_337|Compound:1315-0038|FD-Score:25.50|P-value:2.52E-46 ID:SGTC_343|Compound:4130-2827|FD-Score:7.22|P-value:3.12E-5 ID:SGTC_375|Compound:3970-0961|FD-Score:7.41|P-value:1.99E-5 ID:SGTC_389|Compound:tpck|FD-Score:11.00|P-value:5.41E-10 ID:SGTC_394|Compound:menadione|FD-Score:6.21|P-value:2.94E-4 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:5.77|P-value:7.18E-4 ID:SGTC_413|Compound:propylparaben|FD-Score:8.46|P-value:1.33E-6 ID:SGTC_425|Compound:3825-7017|FD-Score:6.24|P-value:2.78E-4 ID:SGTC_438|Compound:sphingosine|FD-Score:-6.16|P-value:2.26E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:6.48|P-value:1.66E-4 ID:SGTC_486|Compound:niguldipine|FD-Score:35.50|P-value:5.99E-88 ID:SGTC_505|Compound:gw-5074|FD-Score:6.20|P-value:3.04E-4 ID:SGTC_517|Compound:1365-0151|FD-Score:8.42|P-value:1.46E-6 ID:SGTC_534|Compound:k292-0788|FD-Score:5.99|P-value:4.63E-4 ID:SGTC_556|Compound:4058-0063|FD-Score:8.78|P-value:5.40E-7 ID:SGTC_562|Compound:3772-2733|FD-Score:11.60|P-value:6.14E-11 ID:SGTC_563|Compound:tetrahydrosecaminediol|FD-Score:9.37|P-value:9.57E-8 ID:SGTC_569|Compound:4130-2812|FD-Score:19.10|P-value:8.19E-27 ID:SGTC_581|Compound:0958-0271|FD-Score:17.80|P-value:1.49E-23 ID:SGTC_592|Compound:k241-0073|FD-Score:11.90|P-value:1.59E-11 ID:SGTC_603|Compound:3794-0023|FD-Score:7.60|P-value:1.24E-5 ID:SGTC_605|Compound:1315-0399|FD-Score:9.65|P-value:4.01E-8 ID:SGTC_639|Compound:0833-0042|FD-Score:13.80|P-value:7.00E-15 ID:SGTC_650|Compound:1328-0195|FD-Score:5.73|P-value:7.70E-4 ID:SGTC_676|Compound:falcarinol|FD-Score:9.80|P-value:2.52E-8 ID:SGTC_683|Compound:panaxydol|FD-Score:6.10|P-value:3.70E-4 ID:SGTC_700|Compound:3453-2283|FD-Score:18.30|P-value:8.31E-25 ID:SGTC_702|Compound:1488-0190|FD-Score:6.28|P-value:2.57E-4 ID:SGTC_744|Compound:1594-0068|FD-Score:10.20|P-value:6.33E-9 ID:SGTC_749|Compound:1000-0129|FD-Score:7.12|P-value:3.97E-5 ID:SGTC_781|Compound:4335-2806|FD-Score:9.84|P-value:2.24E-8 ID:SGTC_823|Compound:0417-1665|FD-Score:15.30|P-value:6.43E-18 ID:SGTC_825|Compound:1988-2224|FD-Score:10.30|P-value:4.73E-9 ID:SGTC_845|Compound:0330-0138|FD-Score:9.92|P-value:1.76E-8 ID:SGTC_849|Compound:0386-0493|FD-Score:9.37|P-value:9.56E-8 ID:SGTC_860|Compound:0443-0016|FD-Score:7.51|P-value:1.56E-5 ID:SGTC_867|Compound:0518-0118|FD-Score:12.60|P-value:9.49E-13 ID:SGTC_870|Compound:0573-2213|FD-Score:7.10|P-value:4.19E-5 ID:SGTC_872|Compound:0588-0139|FD-Score:7.27|P-value:2.79E-5 ID:SGTC_878|Compound:0828-0289|FD-Score:13.20|P-value:1.08E-13 ID:SGTC_933|Compound:2914-0560|FD-Score:14.40|P-value:4.12E-16 ID:SGTC_942|Compound:3253-1115|FD-Score:5.77|P-value:7.16E-4 ID:SGTC_974|Compound:1326-0144|FD-Score:14.20|P-value:1.25E-15 ID:SGTC_990|Compound:3985-0011|FD-Score:26.40|P-value:1.31E-49 ID:SGTC_1013|Compound:4112-3890|FD-Score:6.43|P-value:1.87E-4 ID:SGTC_1056|Compound:3448-1962|FD-Score:20.50|P-value:1.57E-30 ID:SGTC_1058|Compound:3448-5425|FD-Score:21.50|P-value:1.12E-33 ID:SGTC_1063|Compound:disulfiram|FD-Score:-5.90|P-value:3.94E-4 ID:SGTC_1100|Compound:amiodarone|FD-Score:6.19|P-value:3.09E-4 ID:SGTC_1123|Compound:mangostin|FD-Score:7.30|P-value:2.59E-5 ID:SGTC_1130|Compound:3454-2858|FD-Score:6.29|P-value:2.52E-4 ID:SGTC_1173|Compound:0443-0020|FD-Score:11.20|P-value:2.42E-10 ID:SGTC_1181|Compound:1222-0449|FD-Score:14.90|P-value:4.51E-17 ID:SGTC_1187|Compound:1391-0724|FD-Score:12.20|P-value:6.31E-12 ID:SGTC_1194|Compound:1488-0194|FD-Score:6.28|P-value:2.54E-4 ID:SGTC_1237|Compound:0330-0133|FD-Score:8.42|P-value:1.49E-6 ID:SGTC_1245|Compound:0418-0076|FD-Score:5.67|P-value:8.76E-4 ID:SGTC_1263|Compound:0774-1208|FD-Score:5.74|P-value:7.56E-4 ID:SGTC_1352|Compound:1496-0991|FD-Score:7.34|P-value:2.34E-5 ID:SGTC_1360|Compound:1598-0022|FD-Score:5.79|P-value:6.83E-4 ID:SGTC_1369|Compound:1866-0067|FD-Score:6.69|P-value:1.05E-4 ID:SGTC_1462|Compound:k081-0014|FD-Score:-12.00|P-value:6.36E-12 ID:SGTC_1463|Compound:k081-0032|FD-Score:-11.00|P-value:2.74E-10 ID:SGTC_1474|Compound:0330-0125|FD-Score:6.17|P-value:3.24E-4 ID:SGTC_1478|Compound:0453-0656|FD-Score:6.22|P-value:2.89E-4 ID:SGTC_1508|Compound:1080-0625|FD-Score:9.23|P-value:1.48E-7 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:6.10|P-value:3.70E-4 ID:SGTC_1599|Compound:8-chlro-1-tetrahydronorharmanone|FD-Score:9.20|P-value:1.61E-7 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:7.18|P-value:3.47E-5 ID:SGTC_1614|Compound:st002383|FD-Score:6.02|P-value:4.33E-4 ID:SGTC_1629|Compound:st005085|FD-Score:7.22|P-value:3.16E-5 ID:SGTC_1678|Compound:st019265|FD-Score:8.17|P-value:2.92E-6 ID:SGTC_1699|Compound:st031318|FD-Score:7.17|P-value:3.52E-5 ID:SGTC_1710|Compound:st031758|FD-Score:6.86|P-value:7.25E-5 ID:SGTC_1726|Compound:st035556|FD-Score:10.60|P-value:2.04E-9 ID:SGTC_1759|Compound:st043059|FD-Score:14.90|P-value:4.47E-17 ID:SGTC_1764|Compound:st044502|FD-Score:8.03|P-value:4.21E-6 ID:SGTC_1819|Compound:st053448|FD-Score:6.21|P-value:2.99E-4 ID:SGTC_1824|Compound:st053723|FD-Score:14.20|P-value:1.01E-15 ID:SGTC_1853|Compound:st056710|FD-Score:10.30|P-value:5.77E-9 ID:SGTC_1854|Compound:st056233|FD-Score:7.07|P-value:4.46E-5 ID:SGTC_1864|Compound:st057645|FD-Score:7.30|P-value:2.61E-5 ID:SGTC_1865|Compound:st057639|FD-Score:6.61|P-value:1.28E-4 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:6.37|P-value:2.13E-4 ID:SGTC_1892|Compound:st058411|FD-Score:6.76|P-value:9.18E-5 ID:SGTC_1904|Compound:st060225|FD-Score:-5.68|P-value:6.10E-4 ID:SGTC_1909|Compound:st060837|FD-Score:8.25|P-value:2.36E-6 ID:SGTC_1915|Compound:st067105|FD-Score:7.57|P-value:1.35E-5 ID:SGTC_1953|Compound:st076800|FD-Score:8.12|P-value:3.33E-6 ID:SGTC_1958|Compound:st076513|FD-Score:10.60|P-value:1.80E-9 ID:SGTC_1970|Compound:st070122|FD-Score:5.94|P-value:5.10E-4 ID:SGTC_1975|Compound:st070967|FD-Score:8.16|P-value:2.93E-6 ID:SGTC_2055|Compound:5235184|FD-Score:5.93|P-value:5.21E-4 ID:SGTC_2059|Compound:5238311|FD-Score:7.40|P-value:2.07E-5 ID:SGTC_2090|Compound:5301565|FD-Score:17.70|P-value:2.46E-23 ID:SGTC_2092|Compound:5303694|FD-Score:8.07|P-value:3.78E-6 ID:SGTC_2093|Compound:5331342|FD-Score:21.00|P-value:3.41E-32 ID:SGTC_2094|Compound:5332512|FD-Score:6.61|P-value:1.25E-4 ID:SGTC_2137|Compound:5261020|FD-Score:15.50|P-value:2.67E-18 ID:SGTC_2197|Compound:6588183|FD-Score:5.66|P-value:8.83E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:10.00|P-value:1.25E-8 ID:SGTC_2233|Compound:sulbentine|FD-Score:6.16|P-value:3.29E-4 ID:SGTC_2254|Compound:7938975|FD-Score:12.30|P-value:3.37E-12 ID:SGTC_2255|Compound:7941087|FD-Score:11.10|P-value:2.90E-10 ID:SGTC_2296|Compound:7971656|FD-Score:9.51|P-value:6.21E-8 ID:SGTC_2322|Compound:7413319|FD-Score:9.33|P-value:1.09E-7 ID:SGTC_2335|Compound:9018011|FD-Score:5.67|P-value:8.61E-4 ID:SGTC_2396|Compound:5342950|FD-Score:9.33|P-value:1.07E-7 ID:SGTC_2413|Compound:inermin|FD-Score:5.75|P-value:7.43E-4 ID:SGTC_2424|Compound:5537928|FD-Score:6.74|P-value:9.45E-5 ID:SGTC_2430|Compound:5571206|FD-Score:6.15|P-value:3.34E-4 ID:SGTC_2444|Compound:5485484|FD-Score:8.02|P-value:4.27E-6 ID:SGTC_2447|Compound:5741742|FD-Score:-6.32|P-value:1.62E-4 ID:SGTC_2460|Compound:5552655|FD-Score:41.60|P-value:3.37E-120 ID:SGTC_2461|Compound:5755302|FD-Score:12.80|P-value:5.39E-13 ID:SGTC_2462|Compound:5162487|FD-Score:5.82|P-value:6.49E-4 ID:SGTC_2498|Compound:4'-Methoxychalcone|FD-Score:7.41|P-value:1.99E-5 ID:SGTC_2499|Compound:avocadenofuran|FD-Score:7.12|P-value:4.00E-5 ID:SGTC_2557|Compound:derrustone|FD-Score:6.61|P-value:1.28E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:21.00|P-value:4.58E-32 ID:SGTC_2574|Compound:2',4'-dihydroxychalcone|FD-Score:12.80|P-value:5.26E-13 ID:SGTC_2577|Compound:2',4'-dihydroxy-4-methoxychalcone|FD-Score:12.10|P-value:7.68E-12 ID:SGTC_2579|Compound:2',5'-dihydroxy-4-methoxychalcone|FD-Score:10.50|P-value:2.57E-9 ID:SGTC_2581|Compound:avocatin a|FD-Score:5.92|P-value:5.39E-4 ID:SGTC_2594|Compound:a-mangostin|FD-Score:6.52|P-value:1.54E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:6.65|P-value:1.17E-4 ID:SGTC_2618|Compound:avocadyne|FD-Score:16.00|P-value:2.04E-19 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:10.90|P-value:7.36E-10 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.48|P-value:1.66E-4 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:6.12|P-value:3.59E-4 ID:SGTC_2660|Compound:2',4'-dihydroxychalcone|FD-Score:6.33|P-value:2.30E-4 ID:SGTC_2680|Compound:butyl paraben|FD-Score:7.30|P-value:2.62E-5 ID:SGTC_2683|Compound:piperine|FD-Score:9.81|P-value:2.43E-8 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.21|P-value:3.24E-5 ID:SGTC_2696|Compound:st077691|FD-Score:5.72|P-value:7.87E-4 ID:SGTC_2701|Compound:st077767|FD-Score:9.68|P-value:3.67E-8 ID:SGTC_2774|Compound:tamoxifen|FD-Score:-5.91|P-value:3.82E-4 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:-6.73|P-value:6.63E-5 ID:SGTC_2776|Compound:terbinafine|FD-Score:-7.73|P-value:5.86E-6 ID:SGTC_2833|Compound:9001315|FD-Score:18.80|P-value:3.45E-26 ID:SGTC_2841|Compound:9004761|FD-Score:11.90|P-value:2.04E-11 ID:SGTC_2845|Compound:9003024|FD-Score:39.30|P-value:9.99E-108 ID:SGTC_2852|Compound:9023854|FD-Score:7.29|P-value:2.68E-5 ID:SGTC_2855|Compound:9016525|FD-Score:5.62|P-value:9.58E-4 ID:SGTC_2921|Compound:7974240|FD-Score:8.76|P-value:5.79E-7 ID:SGTC_2924|Compound:9010168|FD-Score:6.13|P-value:3.52E-4 ID:SGTC_2932|Compound:9016711|FD-Score:14.60|P-value:1.90E-16 ID:SGTC_2939|Compound:9044578|FD-Score:6.26|P-value:2.66E-4 ID:SGTC_2976|Compound:9009005|FD-Score:14.80|P-value:8.35E-17 ID:SGTC_2980|Compound:9014342|FD-Score:15.10|P-value:2.22E-17 ID:SGTC_2982|Compound:9019404|FD-Score:9.19|P-value:1.64E-7 ID:SGTC_2999|Compound:9069765|FD-Score:7.31|P-value:2.57E-5 ID:SGTC_3025|Compound:9087895|FD-Score:6.45|P-value:1.79E-4 ID:SGTC_3034|Compound:9090421|FD-Score:6.89|P-value:6.78E-5 ID:SGTC_3065|Compound:9113888|FD-Score:6.83|P-value:7.67E-5 ID:SGTC_3088|Compound:9117578|FD-Score:7.17|P-value:3.57E-5 ID:SGTC_3100|Compound:9120536|FD-Score:5.94|P-value:5.10E-4 ID:SGTC_3101|Compound:9120531|FD-Score:7.58|P-value:1.31E-5 ID:SGTC_3131|Compound:9127911|FD-Score:6.60|P-value:1.30E-4 ID:SGTC_3143|Compound:9086658|FD-Score:6.79|P-value:8.54E-5 ID:SGTC_3155|Compound:9099265|FD-Score:6.04|P-value:4.23E-4 ID:SGTC_3167|Compound:9103034|FD-Score:8.56|P-value:1.00E-6 ID:SGTC_3168|Compound:9103419|FD-Score:6.72|P-value:1.00E-4 ID:SGTC_3174|Compound:9107204|FD-Score:9.30|P-value:1.17E-7 ID:SGTC_3211|Compound:9128781|FD-Score:6.94|P-value:5.99E-5 ID:SGTC_3225|Compound:9130819|FD-Score:13.70|P-value:1.12E-14 ID:SGTC_3228|Compound:9131799|FD-Score:12.50|P-value:1.91E-12 ID:SGTC_3235|Compound:9132602|FD-Score:8.94|P-value:3.38E-7 ID:SGTC_3237|Compound:9133362|FD-Score:15.20|P-value:1.37E-17 ID:SGTC_3292|Compound:9120825|FD-Score:6.09|P-value:3.80E-4 ID:SGTC_3303|Compound:9125618|FD-Score:14.80|P-value:8.92E-17 ID:SGTC_3330|Compound:9141424|FD-Score:12.70|P-value:8.59E-13

Top fitness defect scores for YIR023W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2460 5552655 41.60 174.2 µM 3.37E-120 amide catabolism 1 0
2 SGTC_2845 9003024 39.30 43.0 µM 9.99E-108 amide catabolism 1 0
3 SGTC_486 niguldipine 35.50 82.0 µM 5.99E-88 amide catabolism 1 8.94E-276
4 SGTC_990 3985-0011 26.40 41.3 µM 1.31E-49 amide catabolism 1 7.04E-154
5 SGTC_337 1315-0038 25.50 354.0 µM 2.52E-46 amide catabolism 1 1.89E-143
6 SGTC_1058 3448-5425 21.50 97.3 µM 1.12E-33 1 2.89E-103
7 SGTC_2093 5331342 21.00 194.4 µM 3.41E-32 1 1.48E-98
8 SGTC_2573 2',4'-dihydroxychalcone 21.00 15.0 µM 4.58E-32 1 3.78E-98
9 SGTC_1056 3448-1962 20.50 115.0 µM 1.57E-30 amide catabolism 1 2.82E-93
10 SGTC_569 4130-2812 19.10 160.0 µM 8.19E-27 amide catabolism 1 1.79E-81
11 SGTC_2833 9001315 18.80 45.5 µM 3.45E-26 amide catabolism 1 1.70E-79
12 SGTC_700 3453-2283 18.30 142.0 µM 8.31E-25 amide catabolism 1 4.14E-75
13 SGTC_581 0958-0271 17.80 211.0 µM 1.49E-23 1 3.96E-71
14 SGTC_2090 5301565 17.70 104.5 µM 2.46E-23 TSC3-RPN4 2 1.92E-70
15 SGTC_161 4065-0411 16.60 162.2 µM 1.05E-20 1 4.15E-62
16 SGTC_2618 avocadyne 16.00 43.4 µM 2.04E-19 8 5.09E-58
17 SGTC_2137 5261020 15.50 140.0 µM 2.67E-18 3 1.77E-54
18 SGTC_823 0417-1665 15.30 178.0 µM 6.43E-18 2 2.85E-53
19 SGTC_3237 9133362 15.20 49.5 µM 1.37E-17 1 3.12E-52
20 SGTC_2980 9014342 15.10 25.3 µM 2.22E-17 2 1.44E-51

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.338 8.73E-90 YBR069C TAT1 hom Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress
0.256 6.23E-51 YDR127W ARO1 hom Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
0.232 3.24E-42 YKL211C TRP3 hom Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
0.224 3.10E-39 YML123C PHO84 hom High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity
0.220 7.74E-38 YER090W TRP2 hom Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p
0.208 6.36E-34 YDR008C_d YDR008C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.204 8.73E-33 YGR063C SPT4 hom Component of the universally conserved Spt4/5 complex (DSIF complex); the complex has multiple roles in concert with RNA polymerases I and II, including regulation of transcription elongation, RNA processing, quality control, and transcription-coupled DNA repair; Spt4p also localizes to kinetochores and heterochromatin and affects chromosome dynamics and silencing; required for transcription through lengthy trinucleotide repeats in ORFs or non-protein coding regions
0.200 1.29E-31 YDR007W TRP1 hom Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
0.193 1.74E-29 YHL011C PRS3 hom 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes
0.172 1.11E-23 YPR060C ARO7 hom Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis
0.170 3.71E-23 YDR354W TRP4 hom Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
0.165 6.15E-22 YDR463W STP1 hom Transcription factor; undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing; STP1 has a paralog, STP2, that arose from the whole genome duplication
0.164 1.59E-21 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.156 8.21E-20 YGL026C TRP5 hom Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis
0.155 2.51E-19 YHR062C RPP1 het Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs