YJL004C / SYS1

Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation

Zygosity: Homozygous strain
fixedexpanded
Profile for YJL004C / SYS1

Click on Significant Values for Screen Details ID:SGTC_4|Compound:0960-0234|FD-Score:4.15|P-value:7.94E-4 ID:SGTC_22|Compound:0964-0034|FD-Score:4.58|P-value:2.53E-4 ID:SGTC_56|Compound:0957-0365|FD-Score:5.56|P-value:1.25E-5 ID:SGTC_66|Compound:0109-0187|FD-Score:4.37|P-value:4.46E-4 ID:SGTC_91|Compound:0417-1751|FD-Score:12.10|P-value:4.11E-20 ID:SGTC_93|Compound:0109-0045|FD-Score:5.43|P-value:1.92E-5 ID:SGTC_98|Compound:0074-0023|FD-Score:5.33|P-value:2.65E-5 ID:SGTC_110|Compound:0850-0284|FD-Score:4.16|P-value:7.71E-4 ID:SGTC_124|Compound:0136-0217|FD-Score:7.58|P-value:4.83E-9 ID:SGTC_132|Compound:0417-1715|FD-Score:5.14|P-value:4.82E-5 ID:SGTC_146|Compound:3448-8650|FD-Score:5.25|P-value:3.36E-5 ID:SGTC_263|Compound:alizarin|FD-Score:6.82|P-value:1.23E-7 ID:SGTC_266|Compound:formosanin C|FD-Score:-4.35|P-value:6.31E-4 ID:SGTC_275|Compound:trichlorophene|FD-Score:5.56|P-value:1.22E-5 ID:SGTC_291|Compound:4130-1278|FD-Score:4.18|P-value:7.30E-4 ID:SGTC_347|Compound:4534-1311|FD-Score:5.53|P-value:1.36E-5 ID:SGTC_389|Compound:tpck|FD-Score:6.18|P-value:1.44E-6 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:4.15|P-value:7.90E-4 ID:SGTC_435|Compound:c-PAF|FD-Score:-5.11|P-value:7.36E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.80|P-value:7.85E-6 ID:SGTC_455|Compound:paf C-16|FD-Score:-5.61|P-value:1.50E-5 ID:SGTC_459|Compound:nigericin|FD-Score:6.32|P-value:8.55E-7 ID:SGTC_488|Compound:nitrendipine|FD-Score:5.40|P-value:2.09E-5 ID:SGTC_528|Compound:3492-0019|FD-Score:12.50|P-value:2.49E-21 ID:SGTC_538|Compound:2922-0838|FD-Score:7.20|P-value:2.54E-8 ID:SGTC_581|Compound:0958-0271|FD-Score:4.76|P-value:1.51E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:6.43|P-value:5.50E-7 ID:SGTC_608|Compound:k048-0125|FD-Score:5.01|P-value:7.21E-5 ID:SGTC_632|Compound:0781-2353|FD-Score:6.10|P-value:1.90E-6 ID:SGTC_697|Compound:0508-1955|FD-Score:4.94|P-value:8.83E-5 ID:SGTC_717|Compound:1532-0246|FD-Score:7.17|P-value:2.87E-8 ID:SGTC_718|Compound:1130-0073|FD-Score:6.62|P-value:2.67E-7 ID:SGTC_727|Compound:3032-0951|FD-Score:9.26|P-value:1.31E-12 ID:SGTC_736|Compound:0958-0254|FD-Score:5.84|P-value:4.82E-6 ID:SGTC_748|Compound:0136-0228|FD-Score:7.23|P-value:2.26E-8 ID:SGTC_798|Compound:1287-0182|FD-Score:7.14|P-value:3.32E-8 ID:SGTC_828|Compound:2074-0507|FD-Score:4.59|P-value:2.43E-4 ID:SGTC_863|Compound:0466-0191|FD-Score:4.16|P-value:7.85E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:8.96|P-value:6.42E-12 ID:SGTC_908|Compound:3448-7491|FD-Score:6.23|P-value:1.19E-6 ID:SGTC_999|Compound:4022-0066|FD-Score:14.00|P-value:2.80E-26 ID:SGTC_1060|Compound:3448-7350|FD-Score:7.13|P-value:3.40E-8 ID:SGTC_1064|Compound:honokiol|FD-Score:4.25|P-value:6.14E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:-4.45|P-value:4.83E-4 ID:SGTC_1078|Compound:idebenone|FD-Score:9.05|P-value:4.03E-12 ID:SGTC_1087|Compound:pterostilbene|FD-Score:4.68|P-value:1.91E-4 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:6.17|P-value:1.50E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:-4.20|P-value:9.16E-4 ID:SGTC_1209|Compound:2323-2347|FD-Score:4.49|P-value:3.22E-4 ID:SGTC_1214|Compound:0358-0031|FD-Score:8.83|P-value:1.29E-11 ID:SGTC_1259|Compound:0671-0132|FD-Score:5.77|P-value:6.06E-6 ID:SGTC_1265|Compound:0819-1001|FD-Score:-6.57|P-value:4.93E-7 ID:SGTC_1306|Compound:1185-0270|FD-Score:19.90|P-value:5.13E-51 ID:SGTC_1327|Compound:1436-0082|FD-Score:7.46|P-value:8.27E-9 ID:SGTC_1331|Compound:1472-0049|FD-Score:4.13|P-value:8.29E-4 ID:SGTC_1363|Compound:1636-0063|FD-Score:5.43|P-value:1.88E-5 ID:SGTC_1369|Compound:1866-0067|FD-Score:4.10|P-value:9.08E-4 ID:SGTC_1482|Compound:3346-2049|FD-Score:-4.79|P-value:1.87E-4 ID:SGTC_1495|Compound:4469-0029|FD-Score:7.93|P-value:1.01E-9 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:5.43|P-value:1.88E-5 ID:SGTC_1554|Compound:st069299|FD-Score:4.21|P-value:6.73E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:10.00|P-value:1.94E-14 ID:SGTC_1608|Compound:st001473|FD-Score:5.59|P-value:1.13E-5 ID:SGTC_1655|Compound:st012546|FD-Score:5.16|P-value:4.48E-5 ID:SGTC_1658|Compound:st012944|FD-Score:5.67|P-value:8.68E-6 ID:SGTC_1660|Compound:st012960|FD-Score:4.20|P-value:7.01E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:10.60|P-value:7.81E-16 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:-4.25|P-value:8.23E-4 ID:SGTC_1687|Compound:st020778|FD-Score:8.05|P-value:5.78E-10 ID:SGTC_1715|Compound:st032160|FD-Score:-4.24|P-value:8.44E-4 ID:SGTC_1718|Compound:roemerine|FD-Score:-5.82|P-value:7.53E-6 ID:SGTC_1754|Compound:st042065|FD-Score:-4.43|P-value:5.11E-4 ID:SGTC_1818|Compound:st052136|FD-Score:-4.62|P-value:2.99E-4 ID:SGTC_1829|Compound:berberine|FD-Score:-4.17|P-value:9.99E-4 ID:SGTC_1834|Compound:st055981|FD-Score:4.30|P-value:5.40E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:6.79|P-value:1.37E-7 ID:SGTC_1873|Compound:rapamycin|FD-Score:4.95|P-value:8.62E-5 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:4.08|P-value:9.59E-4 ID:SGTC_1897|Compound:st060201|FD-Score:7.32|P-value:1.54E-8 ID:SGTC_1900|Compound:st060200|FD-Score:9.28|P-value:1.21E-12 ID:SGTC_1903|Compound:st060211|FD-Score:4.38|P-value:4.30E-4 ID:SGTC_1905|Compound:st060207|FD-Score:5.04|P-value:6.50E-5 ID:SGTC_1915|Compound:st067105|FD-Score:5.39|P-value:2.14E-5 ID:SGTC_1917|Compound:st066507|FD-Score:7.30|P-value:1.69E-8 ID:SGTC_1934|Compound:st074720|FD-Score:-4.42|P-value:5.24E-4 ID:SGTC_1935|Compound:st074532|FD-Score:6.76|P-value:1.54E-7 ID:SGTC_1966|Compound:st070145|FD-Score:4.78|P-value:1.43E-4 ID:SGTC_1985|Compound:st071382|FD-Score:5.45|P-value:1.79E-5 ID:SGTC_2007|Compound:4011539|FD-Score:6.44|P-value:5.48E-7 ID:SGTC_2009|Compound:4012297|FD-Score:5.42|P-value:1.96E-5 ID:SGTC_2041|Compound:5107442|FD-Score:8.72|P-value:2.16E-11 ID:SGTC_2144|Compound:5628481|FD-Score:4.44|P-value:3.70E-4 ID:SGTC_2242|Compound:6630449|FD-Score:17.90|P-value:9.45E-42 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-5.21|P-value:5.45E-5 ID:SGTC_2254|Compound:7938975|FD-Score:4.98|P-value:7.91E-5 ID:SGTC_2265|Compound:7929201|FD-Score:-4.29|P-value:7.24E-4 ID:SGTC_2275|Compound:7947463|FD-Score:7.16|P-value:2.98E-8 ID:SGTC_2277|Compound:7947813|FD-Score:5.20|P-value:4.03E-5 ID:SGTC_2278|Compound:7948257|FD-Score:4.22|P-value:6.66E-4 ID:SGTC_2291|Compound:7917025|FD-Score:10.10|P-value:1.43E-14 ID:SGTC_2322|Compound:7413319|FD-Score:4.28|P-value:5.74E-4 ID:SGTC_2363|Compound:9053361|FD-Score:4.86|P-value:1.13E-4 ID:SGTC_2373|Compound:9071805|FD-Score:4.65|P-value:2.07E-4 ID:SGTC_2413|Compound:inermin|FD-Score:6.51|P-value:4.12E-7 ID:SGTC_2447|Compound:5741742|FD-Score:4.28|P-value:5.67E-4 ID:SGTC_2514|Compound:salinomycin|FD-Score:4.13|P-value:8.29E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:14.60|P-value:1.27E-28 ID:SGTC_2619|Compound:obliquin|FD-Score:5.20|P-value:4.02E-5 ID:SGTC_2666|Compound:tannic acid|FD-Score:7.05|P-value:4.78E-8 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:7.10|P-value:3.86E-8 ID:SGTC_2679|Compound:rapamycin|FD-Score:6.64|P-value:2.45E-7 ID:SGTC_2683|Compound:piperine|FD-Score:4.46|P-value:3.48E-4 ID:SGTC_2689|Compound:tacrolimus|FD-Score:5.21|P-value:3.88E-5 ID:SGTC_2735|Compound:sertaconazole|FD-Score:-4.49|P-value:4.37E-4 ID:SGTC_2737|Compound:bleomycin|FD-Score:17.70|P-value:5.39E-41 ID:SGTC_2751|Compound:anetholtrithion|FD-Score:-5.02|P-value:9.64E-5 ID:SGTC_2752|Compound:diclazuril|FD-Score:6.00|P-value:2.74E-6 ID:SGTC_2778|Compound:tioconazole|FD-Score:-4.90|P-value:1.35E-4 ID:SGTC_2833|Compound:9001315|FD-Score:4.21|P-value:6.87E-4 ID:SGTC_2835|Compound:9006588|FD-Score:5.28|P-value:3.08E-5 ID:SGTC_2844|Compound:9010103|FD-Score:-5.73|P-value:1.02E-5 ID:SGTC_2890|Compound:9046729|FD-Score:8.16|P-value:3.52E-10 ID:SGTC_3003|Compound:9075612|FD-Score:6.82|P-value:1.22E-7 ID:SGTC_3166|Compound:9102297|FD-Score:6.52|P-value:3.99E-7 ID:SGTC_3209|Compound:9113616|FD-Score:-4.90|P-value:1.37E-4 ID:SGTC_3219|Compound:9131112|FD-Score:8.81|P-value:1.39E-11 ID:SGTC_3277|Compound:9138724|FD-Score:5.51|P-value:1.45E-5 ID:SGTC_3321|Compound:9137793|FD-Score:5.37|P-value:2.33E-5 ID:SGTC_3325|Compound:9138760|FD-Score:7.33|P-value:1.45E-8 ID:SGTC_4|Compound:0960-0234|FD-Score:4.15|P-value:7.94E-4 ID:SGTC_22|Compound:0964-0034|FD-Score:4.58|P-value:2.53E-4 ID:SGTC_56|Compound:0957-0365|FD-Score:5.56|P-value:1.25E-5 ID:SGTC_66|Compound:0109-0187|FD-Score:4.37|P-value:4.46E-4 ID:SGTC_91|Compound:0417-1751|FD-Score:12.10|P-value:4.11E-20 ID:SGTC_93|Compound:0109-0045|FD-Score:5.43|P-value:1.92E-5 ID:SGTC_98|Compound:0074-0023|FD-Score:5.33|P-value:2.65E-5 ID:SGTC_110|Compound:0850-0284|FD-Score:4.16|P-value:7.71E-4 ID:SGTC_124|Compound:0136-0217|FD-Score:7.58|P-value:4.83E-9 ID:SGTC_132|Compound:0417-1715|FD-Score:5.14|P-value:4.82E-5 ID:SGTC_146|Compound:3448-8650|FD-Score:5.25|P-value:3.36E-5 ID:SGTC_263|Compound:alizarin|FD-Score:6.82|P-value:1.23E-7 ID:SGTC_266|Compound:formosanin C|FD-Score:-4.35|P-value:6.31E-4 ID:SGTC_275|Compound:trichlorophene|FD-Score:5.56|P-value:1.22E-5 ID:SGTC_291|Compound:4130-1278|FD-Score:4.18|P-value:7.30E-4 ID:SGTC_347|Compound:4534-1311|FD-Score:5.53|P-value:1.36E-5 ID:SGTC_389|Compound:tpck|FD-Score:6.18|P-value:1.44E-6 ID:SGTC_390|Compound:dec-rvkr-cmk|FD-Score:4.15|P-value:7.90E-4 ID:SGTC_435|Compound:c-PAF|FD-Score:-5.11|P-value:7.36E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.80|P-value:7.85E-6 ID:SGTC_455|Compound:paf C-16|FD-Score:-5.61|P-value:1.50E-5 ID:SGTC_459|Compound:nigericin|FD-Score:6.32|P-value:8.55E-7 ID:SGTC_488|Compound:nitrendipine|FD-Score:5.40|P-value:2.09E-5 ID:SGTC_528|Compound:3492-0019|FD-Score:12.50|P-value:2.49E-21 ID:SGTC_538|Compound:2922-0838|FD-Score:7.20|P-value:2.54E-8 ID:SGTC_581|Compound:0958-0271|FD-Score:4.76|P-value:1.51E-4 ID:SGTC_605|Compound:1315-0399|FD-Score:6.43|P-value:5.50E-7 ID:SGTC_608|Compound:k048-0125|FD-Score:5.01|P-value:7.21E-5 ID:SGTC_632|Compound:0781-2353|FD-Score:6.10|P-value:1.90E-6 ID:SGTC_697|Compound:0508-1955|FD-Score:4.94|P-value:8.83E-5 ID:SGTC_717|Compound:1532-0246|FD-Score:7.17|P-value:2.87E-8 ID:SGTC_718|Compound:1130-0073|FD-Score:6.62|P-value:2.67E-7 ID:SGTC_727|Compound:3032-0951|FD-Score:9.26|P-value:1.31E-12 ID:SGTC_736|Compound:0958-0254|FD-Score:5.84|P-value:4.82E-6 ID:SGTC_748|Compound:0136-0228|FD-Score:7.23|P-value:2.26E-8 ID:SGTC_798|Compound:1287-0182|FD-Score:7.14|P-value:3.32E-8 ID:SGTC_828|Compound:2074-0507|FD-Score:4.59|P-value:2.43E-4 ID:SGTC_863|Compound:0466-0191|FD-Score:4.16|P-value:7.85E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:8.96|P-value:6.42E-12 ID:SGTC_908|Compound:3448-7491|FD-Score:6.23|P-value:1.19E-6 ID:SGTC_999|Compound:4022-0066|FD-Score:14.00|P-value:2.80E-26 ID:SGTC_1060|Compound:3448-7350|FD-Score:7.13|P-value:3.40E-8 ID:SGTC_1064|Compound:honokiol|FD-Score:4.25|P-value:6.14E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:-4.45|P-value:4.83E-4 ID:SGTC_1078|Compound:idebenone|FD-Score:9.05|P-value:4.03E-12 ID:SGTC_1087|Compound:pterostilbene|FD-Score:4.68|P-value:1.91E-4 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:6.17|P-value:1.50E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:-4.20|P-value:9.16E-4 ID:SGTC_1209|Compound:2323-2347|FD-Score:4.49|P-value:3.22E-4 ID:SGTC_1214|Compound:0358-0031|FD-Score:8.83|P-value:1.29E-11 ID:SGTC_1259|Compound:0671-0132|FD-Score:5.77|P-value:6.06E-6 ID:SGTC_1265|Compound:0819-1001|FD-Score:-6.57|P-value:4.93E-7 ID:SGTC_1306|Compound:1185-0270|FD-Score:19.90|P-value:5.13E-51 ID:SGTC_1327|Compound:1436-0082|FD-Score:7.46|P-value:8.27E-9 ID:SGTC_1331|Compound:1472-0049|FD-Score:4.13|P-value:8.29E-4 ID:SGTC_1363|Compound:1636-0063|FD-Score:5.43|P-value:1.88E-5 ID:SGTC_1369|Compound:1866-0067|FD-Score:4.10|P-value:9.08E-4 ID:SGTC_1482|Compound:3346-2049|FD-Score:-4.79|P-value:1.87E-4 ID:SGTC_1495|Compound:4469-0029|FD-Score:7.93|P-value:1.01E-9 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:5.43|P-value:1.88E-5 ID:SGTC_1554|Compound:st069299|FD-Score:4.21|P-value:6.73E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:10.00|P-value:1.94E-14 ID:SGTC_1608|Compound:st001473|FD-Score:5.59|P-value:1.13E-5 ID:SGTC_1655|Compound:st012546|FD-Score:5.16|P-value:4.48E-5 ID:SGTC_1658|Compound:st012944|FD-Score:5.67|P-value:8.68E-6 ID:SGTC_1660|Compound:st012960|FD-Score:4.20|P-value:7.01E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:10.60|P-value:7.81E-16 ID:SGTC_1680|Compound:diphenhydramine|FD-Score:-4.25|P-value:8.23E-4 ID:SGTC_1687|Compound:st020778|FD-Score:8.05|P-value:5.78E-10 ID:SGTC_1715|Compound:st032160|FD-Score:-4.24|P-value:8.44E-4 ID:SGTC_1718|Compound:roemerine|FD-Score:-5.82|P-value:7.53E-6 ID:SGTC_1754|Compound:st042065|FD-Score:-4.43|P-value:5.11E-4 ID:SGTC_1818|Compound:st052136|FD-Score:-4.62|P-value:2.99E-4 ID:SGTC_1829|Compound:berberine|FD-Score:-4.17|P-value:9.99E-4 ID:SGTC_1834|Compound:st055981|FD-Score:4.30|P-value:5.40E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:6.79|P-value:1.37E-7 ID:SGTC_1873|Compound:rapamycin|FD-Score:4.95|P-value:8.62E-5 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:4.08|P-value:9.59E-4 ID:SGTC_1897|Compound:st060201|FD-Score:7.32|P-value:1.54E-8 ID:SGTC_1900|Compound:st060200|FD-Score:9.28|P-value:1.21E-12 ID:SGTC_1903|Compound:st060211|FD-Score:4.38|P-value:4.30E-4 ID:SGTC_1905|Compound:st060207|FD-Score:5.04|P-value:6.50E-5 ID:SGTC_1915|Compound:st067105|FD-Score:5.39|P-value:2.14E-5 ID:SGTC_1917|Compound:st066507|FD-Score:7.30|P-value:1.69E-8 ID:SGTC_1934|Compound:st074720|FD-Score:-4.42|P-value:5.24E-4 ID:SGTC_1935|Compound:st074532|FD-Score:6.76|P-value:1.54E-7 ID:SGTC_1966|Compound:st070145|FD-Score:4.78|P-value:1.43E-4 ID:SGTC_1985|Compound:st071382|FD-Score:5.45|P-value:1.79E-5 ID:SGTC_2007|Compound:4011539|FD-Score:6.44|P-value:5.48E-7 ID:SGTC_2009|Compound:4012297|FD-Score:5.42|P-value:1.96E-5 ID:SGTC_2041|Compound:5107442|FD-Score:8.72|P-value:2.16E-11 ID:SGTC_2144|Compound:5628481|FD-Score:4.44|P-value:3.70E-4 ID:SGTC_2242|Compound:6630449|FD-Score:17.90|P-value:9.45E-42 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-5.21|P-value:5.45E-5 ID:SGTC_2254|Compound:7938975|FD-Score:4.98|P-value:7.91E-5 ID:SGTC_2265|Compound:7929201|FD-Score:-4.29|P-value:7.24E-4 ID:SGTC_2275|Compound:7947463|FD-Score:7.16|P-value:2.98E-8 ID:SGTC_2277|Compound:7947813|FD-Score:5.20|P-value:4.03E-5 ID:SGTC_2278|Compound:7948257|FD-Score:4.22|P-value:6.66E-4 ID:SGTC_2291|Compound:7917025|FD-Score:10.10|P-value:1.43E-14 ID:SGTC_2322|Compound:7413319|FD-Score:4.28|P-value:5.74E-4 ID:SGTC_2363|Compound:9053361|FD-Score:4.86|P-value:1.13E-4 ID:SGTC_2373|Compound:9071805|FD-Score:4.65|P-value:2.07E-4 ID:SGTC_2413|Compound:inermin|FD-Score:6.51|P-value:4.12E-7 ID:SGTC_2447|Compound:5741742|FD-Score:4.28|P-value:5.67E-4 ID:SGTC_2514|Compound:salinomycin|FD-Score:4.13|P-value:8.29E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:14.60|P-value:1.27E-28 ID:SGTC_2619|Compound:obliquin|FD-Score:5.20|P-value:4.02E-5 ID:SGTC_2666|Compound:tannic acid|FD-Score:7.05|P-value:4.78E-8 ID:SGTC_2675|Compound:theaflavin digallate|FD-Score:7.10|P-value:3.86E-8 ID:SGTC_2679|Compound:rapamycin|FD-Score:6.64|P-value:2.45E-7 ID:SGTC_2683|Compound:piperine|FD-Score:4.46|P-value:3.48E-4 ID:SGTC_2689|Compound:tacrolimus|FD-Score:5.21|P-value:3.88E-5 ID:SGTC_2735|Compound:sertaconazole|FD-Score:-4.49|P-value:4.37E-4 ID:SGTC_2737|Compound:bleomycin|FD-Score:17.70|P-value:5.39E-41 ID:SGTC_2751|Compound:anetholtrithion|FD-Score:-5.02|P-value:9.64E-5 ID:SGTC_2752|Compound:diclazuril|FD-Score:6.00|P-value:2.74E-6 ID:SGTC_2778|Compound:tioconazole|FD-Score:-4.90|P-value:1.35E-4 ID:SGTC_2833|Compound:9001315|FD-Score:4.21|P-value:6.87E-4 ID:SGTC_2835|Compound:9006588|FD-Score:5.28|P-value:3.08E-5 ID:SGTC_2844|Compound:9010103|FD-Score:-5.73|P-value:1.02E-5 ID:SGTC_2890|Compound:9046729|FD-Score:8.16|P-value:3.52E-10 ID:SGTC_3003|Compound:9075612|FD-Score:6.82|P-value:1.22E-7 ID:SGTC_3166|Compound:9102297|FD-Score:6.52|P-value:3.99E-7 ID:SGTC_3209|Compound:9113616|FD-Score:-4.90|P-value:1.37E-4 ID:SGTC_3219|Compound:9131112|FD-Score:8.81|P-value:1.39E-11 ID:SGTC_3277|Compound:9138724|FD-Score:5.51|P-value:1.45E-5 ID:SGTC_3321|Compound:9137793|FD-Score:5.37|P-value:2.33E-5 ID:SGTC_3325|Compound:9138760|FD-Score:7.33|P-value:1.45E-8

Top fitness defect scores for YJL004C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_1306 1185-0270 19.90 9.0 µM 5.13E-51 Golgi 2 2.54E-88
2 SGTC_2242 6630449 17.90 61.3 µM 9.45E-42 Golgi 1 5.61E-72
3 SGTC_2737 bleomycin 17.70 30.5 nM 5.39E-41 Golgi 2 1.21E-70
4 SGTC_2567 aureobasidin a 14.60 60.0 nM 1.27E-28 4 7.61E-49
5 SGTC_999 4022-0066 14.00 22.7 µM 2.80E-26 Golgi 3 1.02E-44
6 SGTC_528 3492-0019 12.50 172.0 µM 2.49E-21 calcium & mitochondrial duress 26 5.10E-36
7 SGTC_91 0417-1751 12.10 58.4 µM 4.11E-20 Golgi 3 7.04E-34
8 SGTC_1679 4130-1276 10.60 6.7 µM 7.81E-16 Golgi 9 2.27E-26
9 SGTC_2291 7917025 10.10 104.3 µM 1.43E-14 iron homeostasis 7 3.69E-24
10 SGTC_1581 himbacine 10.00 57.9 µM 1.94E-14 Golgi 6 6.29E-24
11 SGTC_1900 st060200 9.28 72.8 µM 1.21E-12 1 8.77E-21
12 SGTC_727 3032-0951 9.26 202.0 µM 1.31E-12 1 9.99E-21
13 SGTC_1078 idebenone 9.05 36.1 µM 4.03E-12 Golgi 4 7.15E-20
14 SGTC_878 0828-0289 8.96 13.7 µM 6.42E-12 6 1.61E-19
15 SGTC_1214 0358-0031 8.83 63.7 µM 1.29E-11 1 5.43E-19
16 SGTC_3219 9131112 8.81 49.5 µM 1.39E-11 Golgi 7 6.19E-19
17 SGTC_2041 5107442 8.72 45.3 µM 2.16E-11 RSC complex & mRNA processing 6 1.34E-18
18 SGTC_2890 9046729 8.16 58.4 µM 3.52E-10 Golgi 3 1.74E-16
19 SGTC_1687 st020778 8.05 55.4 µM 5.78E-10 69 4.14E-16
20 SGTC_1495 4469-0029 7.93 237.0 µM 1.01E-9 25 1.09E-15

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.554 7.04E-269 YPL051W ARL3 hom GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
0.528 6.76E-240 YBR164C ARL1 hom Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
0.402 2.24E-130 YML071C COG8 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.370 3.71E-109 YGL005C COG7 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.317 6.83E-79 YNL041C COG6 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.305 6.93E-73 YDR108W TRS85 hom Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
0.288 6.92E-65 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.283 2.47E-62 YOL018C TLG2 hom Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)
0.266 1.56E-55 YEL053C MAK10 hom Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible
0.245 3.56E-47 YDL192W ARF1 hom ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; ARF1 has a paralog, ARF2, that arose from the whole genome duplication
0.244 1.85E-46 YGL095C VPS45 hom Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment
0.231 6.54E-42 YDR320C SWA2 hom Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles
0.224 2.15E-39 YDR170C SEC7 het Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles
0.216 1.62E-36 YAL002W VPS8 hom Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif
0.213 9.32E-36 YOR036W PEP12 hom Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin