YJL086C_d

Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL085W/EXO70 and YJL087C/TRL1

Zygosity: Heterozygous strain
fixedexpanded
Profile for YJL086C / YJL086C

Click on Significant Values for Screen Details ID:SGTC_50|Compound:0929-0078|FD-Score:-5.94|P-value:1.94E-6 ID:SGTC_57|Compound:miconazole|FD-Score:-6.02|P-value:1.46E-6 ID:SGTC_63|Compound:0099-0242|FD-Score:8.44|P-value:2.71E-11 ID:SGTC_64|Compound:000l-0018|FD-Score:5.07|P-value:4.03E-5 ID:SGTC_70|Compound:0141-0289|FD-Score:7.65|P-value:1.37E-9 ID:SGTC_86|Compound:0417-1630|FD-Score:6.37|P-value:3.61E-7 ID:SGTC_88|Compound:0180-0332|FD-Score:4.13|P-value:6.63E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:5.82|P-value:2.95E-6 ID:SGTC_146|Compound:3448-8650|FD-Score:4.13|P-value:6.64E-4 ID:SGTC_157|Compound:1348-1695|FD-Score:-4.87|P-value:7.70E-5 ID:SGTC_168|Compound:3970-0862|FD-Score:6.51|P-value:2.04E-7 ID:SGTC_178|Compound:4092-0806|FD-Score:5.90|P-value:2.20E-6 ID:SGTC_206|Compound:4546-0025|FD-Score:5.77|P-value:3.63E-6 ID:SGTC_207|Compound:4185-0010|FD-Score:6.08|P-value:1.13E-6 ID:SGTC_221|Compound:trifluoperazine|FD-Score:9.28|P-value:2.65E-13 ID:SGTC_236|Compound:1509-0011|FD-Score:5.57|P-value:7.40E-6 ID:SGTC_284|Compound:0988-0104|FD-Score:-5.68|P-value:5.08E-6 ID:SGTC_308|Compound:4092-1169|FD-Score:4.29|P-value:4.28E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:-4.12|P-value:6.92E-4 ID:SGTC_343|Compound:4130-2827|FD-Score:4.19|P-value:5.52E-4 ID:SGTC_350|Compound:k064-0020|FD-Score:-5.65|P-value:5.68E-6 ID:SGTC_434|Compound:1-hexadecyl-2-methylglycero-3 PC|FD-Score:-5.10|P-value:3.69E-5 ID:SGTC_435|Compound:c-PAF|FD-Score:-4.49|P-value:2.44E-4 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.61|P-value:1.69E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-6.78|P-value:6.84E-8 ID:SGTC_455|Compound:paf C-16|FD-Score:-5.03|P-value:4.70E-5 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:6.74|P-value:8.12E-8 ID:SGTC_462|Compound:ag-879|FD-Score:4.10|P-value:7.13E-4 ID:SGTC_501|Compound:nsc-95397|FD-Score:4.12|P-value:6.80E-4 ID:SGTC_515|Compound:4092-1064|FD-Score:4.85|P-value:8.22E-5 ID:SGTC_539|Compound:4859-0462|FD-Score:4.43|P-value:2.82E-4 ID:SGTC_550|Compound:4123-0385|FD-Score:4.55|P-value:2.04E-4 ID:SGTC_568|Compound:1193-0097|FD-Score:7.00|P-value:2.65E-8 ID:SGTC_574|Compound:1315-0397|FD-Score:4.45|P-value:2.67E-4 ID:SGTC_577|Compound:r071-0003|FD-Score:4.02|P-value:8.80E-4 ID:SGTC_721|Compound:1187-1332|FD-Score:4.15|P-value:6.29E-4 ID:SGTC_730|Compound:1436-0052|FD-Score:4.80|P-value:9.44E-5 ID:SGTC_745|Compound:0469-0705|FD-Score:4.32|P-value:3.89E-4 ID:SGTC_768|Compound:0384-0033|FD-Score:8.27|P-value:6.51E-11 ID:SGTC_778|Compound:3456-2434|FD-Score:-5.74|P-value:4.18E-6 ID:SGTC_788|Compound:1182-0090|FD-Score:10.90|P-value:1.08E-17 ID:SGTC_789|Compound:1309-1135|FD-Score:4.39|P-value:3.23E-4 ID:SGTC_808|Compound:0711-0032|FD-Score:4.33|P-value:3.74E-4 ID:SGTC_834|Compound:0312-0008|FD-Score:4.90|P-value:6.85E-5 ID:SGTC_851|Compound:0394-0702|FD-Score:9.78|P-value:1.41E-14 ID:SGTC_908|Compound:3448-7491|FD-Score:5.33|P-value:1.68E-5 ID:SGTC_913|Compound:3487-1245|FD-Score:4.18|P-value:5.77E-4 ID:SGTC_915|Compound:methyl methanesulfonate (MMS)|FD-Score:7.92|P-value:3.62E-10 ID:SGTC_946|Compound:3434-1334|FD-Score:6.07|P-value:1.20E-6 ID:SGTC_1001|Compound:4048-4355|FD-Score:6.47|P-value:2.46E-7 ID:SGTC_1026|Compound:k007-1105|FD-Score:4.71|P-value:1.26E-4 ID:SGTC_1057|Compound:3448-5381|FD-Score:4.12|P-value:6.68E-4 ID:SGTC_1154|Compound:4088-0362|FD-Score:4.19|P-value:5.60E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:8.09|P-value:1.56E-10 ID:SGTC_1188|Compound:1403-0014|FD-Score:6.02|P-value:1.42E-6 ID:SGTC_1230|Compound:0170-0365|FD-Score:9.60|P-value:4.27E-14 ID:SGTC_1265|Compound:0819-1001|FD-Score:5.73|P-value:4.17E-6 ID:SGTC_1308|Compound:1187-1617|FD-Score:4.71|P-value:1.26E-4 ID:SGTC_1347|Compound:1493-0251|FD-Score:-4.36|P-value:3.50E-4 ID:SGTC_1353|Compound:1498-1206|FD-Score:-4.37|P-value:3.40E-4 ID:SGTC_1371|Compound:2421-0008|FD-Score:5.65|P-value:5.59E-6 ID:SGTC_1447|Compound:4239-0816|FD-Score:5.38|P-value:1.41E-5 ID:SGTC_1459|Compound:k035-0031|FD-Score:4.20|P-value:5.48E-4 ID:SGTC_1478|Compound:0453-0656|FD-Score:4.18|P-value:5.79E-4 ID:SGTC_1629|Compound:st005085|FD-Score:4.00|P-value:9.30E-4 ID:SGTC_1646|Compound:st011709|FD-Score:5.00|P-value:4.97E-5 ID:SGTC_1672|Compound:st016598|FD-Score:5.33|P-value:1.72E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.40|P-value:2.83E-19 ID:SGTC_1707|Compound:st032323|FD-Score:-4.92|P-value:6.71E-5 ID:SGTC_1754|Compound:st042065|FD-Score:5.39|P-value:1.39E-5 ID:SGTC_1784|Compound:st039334|FD-Score:6.44|P-value:2.73E-7 ID:SGTC_1786|Compound:berberine|FD-Score:14.40|P-value:2.94E-29 ID:SGTC_1787|Compound:fluconazole|FD-Score:-4.62|P-value:1.68E-4 ID:SGTC_1789|Compound:tunicamycin|FD-Score:-4.99|P-value:5.24E-5 ID:SGTC_1800|Compound:st050079|FD-Score:4.60|P-value:1.72E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.88|P-value:4.48E-8 ID:SGTC_1818|Compound:st052136|FD-Score:4.79|P-value:9.74E-5 ID:SGTC_1827|Compound:berberine|FD-Score:7.35|P-value:5.40E-9 ID:SGTC_1829|Compound:berberine|FD-Score:7.90|P-value:4.01E-10 ID:SGTC_1844|Compound:rapamycin|FD-Score:-4.19|P-value:5.75E-4 ID:SGTC_1864|Compound:st057645|FD-Score:4.48|P-value:2.45E-4 ID:SGTC_1873|Compound:rapamycin|FD-Score:-4.54|P-value:2.12E-4 ID:SGTC_1877|Compound:wortmannin|FD-Score:5.04|P-value:4.37E-5 ID:SGTC_1962|Compound:st076595|FD-Score:4.74|P-value:1.13E-4 ID:SGTC_1991|Compound:st073000|FD-Score:7.30|P-value:6.77E-9 ID:SGTC_1992|Compound:st073643|FD-Score:4.09|P-value:7.42E-4 ID:SGTC_2006|Compound:4011487|FD-Score:6.86|P-value:4.75E-8 ID:SGTC_2021|Compound:4019055|FD-Score:11.60|P-value:7.01E-20 ID:SGTC_2036|Compound:5160441|FD-Score:10.90|P-value:1.02E-17 ID:SGTC_2053|Compound:5265679|FD-Score:4.75|P-value:1.10E-4 ID:SGTC_2085|Compound:5307070|FD-Score:5.00|P-value:5.11E-5 ID:SGTC_2129|Compound:girgensonine|FD-Score:7.28|P-value:7.70E-9 ID:SGTC_2168|Compound:5727979|FD-Score:4.50|P-value:2.31E-4 ID:SGTC_2179|Compound:6298986|FD-Score:5.87|P-value:2.52E-6 ID:SGTC_2183|Compound:6420625|FD-Score:10.20|P-value:1.41E-15 ID:SGTC_2239|Compound:6685329|FD-Score:-4.29|P-value:4.28E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.75|P-value:3.90E-6 ID:SGTC_2257|Compound:7960413|FD-Score:4.53|P-value:2.15E-4 ID:SGTC_2286|Compound:7945697|FD-Score:-7.63|P-value:1.55E-9 ID:SGTC_2336|Compound:9001819|FD-Score:7.09|P-value:1.79E-8 ID:SGTC_2376|Compound:9072922|FD-Score:-4.19|P-value:5.71E-4 ID:SGTC_2398|Compound:5228213|FD-Score:6.33|P-value:4.26E-7 ID:SGTC_2421|Compound:5690543|FD-Score:-4.90|P-value:7.12E-5 ID:SGTC_2477|Compound:5967686|FD-Score:4.48|P-value:2.45E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:4.35|P-value:3.62E-4 ID:SGTC_2511|Compound:berberine|FD-Score:4.80|P-value:9.31E-5 ID:SGTC_2557|Compound:derrustone|FD-Score:4.09|P-value:7.26E-4 ID:SGTC_2575|Compound:plumbagin|FD-Score:4.37|P-value:3.34E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:-4.42|P-value:3.01E-4 ID:SGTC_2633|Compound:5,7-dihydroxyisoflavone|FD-Score:-4.45|P-value:2.76E-4 ID:SGTC_2640|Compound:pentamidine|FD-Score:6.30|P-value:4.77E-7 ID:SGTC_2743|Compound:auranofin|FD-Score:5.89|P-value:2.34E-6 ID:SGTC_2802|Compound:7925815|FD-Score:4.66|P-value:1.44E-4 ID:SGTC_2833|Compound:9001315|FD-Score:-6.60|P-value:1.50E-7 ID:SGTC_2849|Compound:9019321|FD-Score:-4.63|P-value:1.63E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-4.97|P-value:5.62E-5 ID:SGTC_2896|Compound:9052656|FD-Score:5.03|P-value:4.63E-5 ID:SGTC_2928|Compound:9011484|FD-Score:4.00|P-value:9.20E-4 ID:SGTC_2930|Compound:9013230|FD-Score:3.98|P-value:9.76E-4 ID:SGTC_2993|Compound:9054257|FD-Score:5.90|P-value:2.24E-6 ID:SGTC_3006|Compound:9075424|FD-Score:3.99|P-value:9.68E-4 ID:SGTC_3055|Compound:9094636|FD-Score:9.36|P-value:1.66E-13 ID:SGTC_3062|Compound:9077494|FD-Score:-5.46|P-value:1.10E-5 ID:SGTC_3127|Compound:9126946|FD-Score:5.28|P-value:2.04E-5 ID:SGTC_3152|Compound:9099253|FD-Score:8.76|P-value:4.78E-12 ID:SGTC_3334|Compound:9142812|FD-Score:4.06|P-value:8.03E-4 ID:SGTC_3341|Compound:9147222|FD-Score:-4.50|P-value:2.40E-4 ID:SGTC_50|Compound:0929-0078|FD-Score:-5.94|P-value:1.94E-6 ID:SGTC_57|Compound:miconazole|FD-Score:-6.02|P-value:1.46E-6 ID:SGTC_63|Compound:0099-0242|FD-Score:8.44|P-value:2.71E-11 ID:SGTC_64|Compound:000l-0018|FD-Score:5.07|P-value:4.03E-5 ID:SGTC_70|Compound:0141-0289|FD-Score:7.65|P-value:1.37E-9 ID:SGTC_86|Compound:0417-1630|FD-Score:6.37|P-value:3.61E-7 ID:SGTC_88|Compound:0180-0332|FD-Score:4.13|P-value:6.63E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:5.82|P-value:2.95E-6 ID:SGTC_146|Compound:3448-8650|FD-Score:4.13|P-value:6.64E-4 ID:SGTC_157|Compound:1348-1695|FD-Score:-4.87|P-value:7.70E-5 ID:SGTC_168|Compound:3970-0862|FD-Score:6.51|P-value:2.04E-7 ID:SGTC_178|Compound:4092-0806|FD-Score:5.90|P-value:2.20E-6 ID:SGTC_206|Compound:4546-0025|FD-Score:5.77|P-value:3.63E-6 ID:SGTC_207|Compound:4185-0010|FD-Score:6.08|P-value:1.13E-6 ID:SGTC_221|Compound:trifluoperazine|FD-Score:9.28|P-value:2.65E-13 ID:SGTC_236|Compound:1509-0011|FD-Score:5.57|P-value:7.40E-6 ID:SGTC_284|Compound:0988-0104|FD-Score:-5.68|P-value:5.08E-6 ID:SGTC_308|Compound:4092-1169|FD-Score:4.29|P-value:4.28E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:-4.12|P-value:6.92E-4 ID:SGTC_343|Compound:4130-2827|FD-Score:4.19|P-value:5.52E-4 ID:SGTC_350|Compound:k064-0020|FD-Score:-5.65|P-value:5.68E-6 ID:SGTC_434|Compound:1-hexadecyl-2-methylglycero-3 PC|FD-Score:-5.10|P-value:3.69E-5 ID:SGTC_435|Compound:c-PAF|FD-Score:-4.49|P-value:2.44E-4 ID:SGTC_451|Compound:chloral hydrate|FD-Score:4.61|P-value:1.69E-4 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-6.78|P-value:6.84E-8 ID:SGTC_455|Compound:paf C-16|FD-Score:-5.03|P-value:4.70E-5 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:6.74|P-value:8.12E-8 ID:SGTC_462|Compound:ag-879|FD-Score:4.10|P-value:7.13E-4 ID:SGTC_501|Compound:nsc-95397|FD-Score:4.12|P-value:6.80E-4 ID:SGTC_515|Compound:4092-1064|FD-Score:4.85|P-value:8.22E-5 ID:SGTC_539|Compound:4859-0462|FD-Score:4.43|P-value:2.82E-4 ID:SGTC_550|Compound:4123-0385|FD-Score:4.55|P-value:2.04E-4 ID:SGTC_568|Compound:1193-0097|FD-Score:7.00|P-value:2.65E-8 ID:SGTC_574|Compound:1315-0397|FD-Score:4.45|P-value:2.67E-4 ID:SGTC_577|Compound:r071-0003|FD-Score:4.02|P-value:8.80E-4 ID:SGTC_721|Compound:1187-1332|FD-Score:4.15|P-value:6.29E-4 ID:SGTC_730|Compound:1436-0052|FD-Score:4.80|P-value:9.44E-5 ID:SGTC_745|Compound:0469-0705|FD-Score:4.32|P-value:3.89E-4 ID:SGTC_768|Compound:0384-0033|FD-Score:8.27|P-value:6.51E-11 ID:SGTC_778|Compound:3456-2434|FD-Score:-5.74|P-value:4.18E-6 ID:SGTC_788|Compound:1182-0090|FD-Score:10.90|P-value:1.08E-17 ID:SGTC_789|Compound:1309-1135|FD-Score:4.39|P-value:3.23E-4 ID:SGTC_808|Compound:0711-0032|FD-Score:4.33|P-value:3.74E-4 ID:SGTC_834|Compound:0312-0008|FD-Score:4.90|P-value:6.85E-5 ID:SGTC_851|Compound:0394-0702|FD-Score:9.78|P-value:1.41E-14 ID:SGTC_908|Compound:3448-7491|FD-Score:5.33|P-value:1.68E-5 ID:SGTC_913|Compound:3487-1245|FD-Score:4.18|P-value:5.77E-4 ID:SGTC_915|Compound:methyl methanesulfonate (MMS)|FD-Score:7.92|P-value:3.62E-10 ID:SGTC_946|Compound:3434-1334|FD-Score:6.07|P-value:1.20E-6 ID:SGTC_1001|Compound:4048-4355|FD-Score:6.47|P-value:2.46E-7 ID:SGTC_1026|Compound:k007-1105|FD-Score:4.71|P-value:1.26E-4 ID:SGTC_1057|Compound:3448-5381|FD-Score:4.12|P-value:6.68E-4 ID:SGTC_1154|Compound:4088-0362|FD-Score:4.19|P-value:5.60E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:8.09|P-value:1.56E-10 ID:SGTC_1188|Compound:1403-0014|FD-Score:6.02|P-value:1.42E-6 ID:SGTC_1230|Compound:0170-0365|FD-Score:9.60|P-value:4.27E-14 ID:SGTC_1265|Compound:0819-1001|FD-Score:5.73|P-value:4.17E-6 ID:SGTC_1308|Compound:1187-1617|FD-Score:4.71|P-value:1.26E-4 ID:SGTC_1347|Compound:1493-0251|FD-Score:-4.36|P-value:3.50E-4 ID:SGTC_1353|Compound:1498-1206|FD-Score:-4.37|P-value:3.40E-4 ID:SGTC_1371|Compound:2421-0008|FD-Score:5.65|P-value:5.59E-6 ID:SGTC_1447|Compound:4239-0816|FD-Score:5.38|P-value:1.41E-5 ID:SGTC_1459|Compound:k035-0031|FD-Score:4.20|P-value:5.48E-4 ID:SGTC_1478|Compound:0453-0656|FD-Score:4.18|P-value:5.79E-4 ID:SGTC_1629|Compound:st005085|FD-Score:4.00|P-value:9.30E-4 ID:SGTC_1646|Compound:st011709|FD-Score:5.00|P-value:4.97E-5 ID:SGTC_1672|Compound:st016598|FD-Score:5.33|P-value:1.72E-5 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.40|P-value:2.83E-19 ID:SGTC_1707|Compound:st032323|FD-Score:-4.92|P-value:6.71E-5 ID:SGTC_1754|Compound:st042065|FD-Score:5.39|P-value:1.39E-5 ID:SGTC_1784|Compound:st039334|FD-Score:6.44|P-value:2.73E-7 ID:SGTC_1786|Compound:berberine|FD-Score:14.40|P-value:2.94E-29 ID:SGTC_1787|Compound:fluconazole|FD-Score:-4.62|P-value:1.68E-4 ID:SGTC_1789|Compound:tunicamycin|FD-Score:-4.99|P-value:5.24E-5 ID:SGTC_1800|Compound:st050079|FD-Score:4.60|P-value:1.72E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.88|P-value:4.48E-8 ID:SGTC_1818|Compound:st052136|FD-Score:4.79|P-value:9.74E-5 ID:SGTC_1827|Compound:berberine|FD-Score:7.35|P-value:5.40E-9 ID:SGTC_1829|Compound:berberine|FD-Score:7.90|P-value:4.01E-10 ID:SGTC_1844|Compound:rapamycin|FD-Score:-4.19|P-value:5.75E-4 ID:SGTC_1864|Compound:st057645|FD-Score:4.48|P-value:2.45E-4 ID:SGTC_1873|Compound:rapamycin|FD-Score:-4.54|P-value:2.12E-4 ID:SGTC_1877|Compound:wortmannin|FD-Score:5.04|P-value:4.37E-5 ID:SGTC_1962|Compound:st076595|FD-Score:4.74|P-value:1.13E-4 ID:SGTC_1991|Compound:st073000|FD-Score:7.30|P-value:6.77E-9 ID:SGTC_1992|Compound:st073643|FD-Score:4.09|P-value:7.42E-4 ID:SGTC_2006|Compound:4011487|FD-Score:6.86|P-value:4.75E-8 ID:SGTC_2021|Compound:4019055|FD-Score:11.60|P-value:7.01E-20 ID:SGTC_2036|Compound:5160441|FD-Score:10.90|P-value:1.02E-17 ID:SGTC_2053|Compound:5265679|FD-Score:4.75|P-value:1.10E-4 ID:SGTC_2085|Compound:5307070|FD-Score:5.00|P-value:5.11E-5 ID:SGTC_2129|Compound:girgensonine|FD-Score:7.28|P-value:7.70E-9 ID:SGTC_2168|Compound:5727979|FD-Score:4.50|P-value:2.31E-4 ID:SGTC_2179|Compound:6298986|FD-Score:5.87|P-value:2.52E-6 ID:SGTC_2183|Compound:6420625|FD-Score:10.20|P-value:1.41E-15 ID:SGTC_2239|Compound:6685329|FD-Score:-4.29|P-value:4.28E-4 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.75|P-value:3.90E-6 ID:SGTC_2257|Compound:7960413|FD-Score:4.53|P-value:2.15E-4 ID:SGTC_2286|Compound:7945697|FD-Score:-7.63|P-value:1.55E-9 ID:SGTC_2336|Compound:9001819|FD-Score:7.09|P-value:1.79E-8 ID:SGTC_2376|Compound:9072922|FD-Score:-4.19|P-value:5.71E-4 ID:SGTC_2398|Compound:5228213|FD-Score:6.33|P-value:4.26E-7 ID:SGTC_2421|Compound:5690543|FD-Score:-4.90|P-value:7.12E-5 ID:SGTC_2477|Compound:5967686|FD-Score:4.48|P-value:2.45E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:4.35|P-value:3.62E-4 ID:SGTC_2511|Compound:berberine|FD-Score:4.80|P-value:9.31E-5 ID:SGTC_2557|Compound:derrustone|FD-Score:4.09|P-value:7.26E-4 ID:SGTC_2575|Compound:plumbagin|FD-Score:4.37|P-value:3.34E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:-4.42|P-value:3.01E-4 ID:SGTC_2633|Compound:5,7-dihydroxyisoflavone|FD-Score:-4.45|P-value:2.76E-4 ID:SGTC_2640|Compound:pentamidine|FD-Score:6.30|P-value:4.77E-7 ID:SGTC_2743|Compound:auranofin|FD-Score:5.89|P-value:2.34E-6 ID:SGTC_2802|Compound:7925815|FD-Score:4.66|P-value:1.44E-4 ID:SGTC_2833|Compound:9001315|FD-Score:-6.60|P-value:1.50E-7 ID:SGTC_2849|Compound:9019321|FD-Score:-4.63|P-value:1.63E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-4.97|P-value:5.62E-5 ID:SGTC_2896|Compound:9052656|FD-Score:5.03|P-value:4.63E-5 ID:SGTC_2928|Compound:9011484|FD-Score:4.00|P-value:9.20E-4 ID:SGTC_2930|Compound:9013230|FD-Score:3.98|P-value:9.76E-4 ID:SGTC_2993|Compound:9054257|FD-Score:5.90|P-value:2.24E-6 ID:SGTC_3006|Compound:9075424|FD-Score:3.99|P-value:9.68E-4 ID:SGTC_3055|Compound:9094636|FD-Score:9.36|P-value:1.66E-13 ID:SGTC_3062|Compound:9077494|FD-Score:-5.46|P-value:1.10E-5 ID:SGTC_3127|Compound:9126946|FD-Score:5.28|P-value:2.04E-5 ID:SGTC_3152|Compound:9099253|FD-Score:8.76|P-value:4.78E-12 ID:SGTC_3334|Compound:9142812|FD-Score:4.06|P-value:8.03E-4 ID:SGTC_3341|Compound:9147222|FD-Score:-4.50|P-value:2.40E-4

Top fitness defect scores for YJL086C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1786 berberine 14.40 21.6 µM 2.94E-29 60S ribosome export 3 4.24E-47 4.99
2 SGTC_2021 4019055 11.60 173.0 µM 7.01E-20 endomembrane recycling 6 1.23E-31 0.85
3 SGTC_1679 4130-1276 11.40 6.7 µM 2.83E-19 Golgi 4 1.23E-30 0.38
4 SGTC_2036 5160441 10.90 105.0 µM 1.02E-17 NEO1 4 4.46E-28 1.44
5 SGTC_788 1182-0090 10.90 188.0 µM 1.08E-17 endomembrane recycling 1 4.95E-28 2.06
6 SGTC_2183 6420625 10.20 130.5 µM 1.41E-15 mitochondrial processes 2 1.49E-24 2.17
7 SGTC_851 0394-0702 9.78 453.0 µM 1.41E-14 mitochondrial processes 1 6.61E-23 1.62
8 SGTC_1230 0170-0365 9.60 3.8 µM 4.27E-14 endomembrane recycling 7 4.08E-22 1.70
9 SGTC_3055 9094636 9.36 49.5 µM 1.66E-13 1 3.83E-21 4.16
10 SGTC_221 trifluoperazine 9.28 10.3 µM 2.65E-13 NEO1-PIK1 7 8.21E-21 0.64
11 SGTC_3152 9099253 8.76 49.5 µM 4.78E-12 NEO1-PIK1 7 9.51E-19 0.89
12 SGTC_63 0099-0242 8.44 26.7 µM 2.71E-11 mitochondrial stress 6 1.64E-17 0.22
13 SGTC_768 0384-0033 8.27 77.3 µM 6.51E-11 fatty acid desaturase (OLE1) 5 6.92E-17 1.14
14 SGTC_1161 k007-0610 8.09 110.0 µM 1.56E-10 ERAD & cell cycle 10 2.91E-16 0.28
15 SGTC_915 methyl methanesulfonate (MMS) 7.92 110.0 mM 3.62E-10 DNA damage response 2 1.15E-15 1.65
16 SGTC_1829 berberine 7.90 14.4 µM 4.01E-10 60S ribosome export 5 1.36E-15 0.99
17 SGTC_70 0141-0289 7.65 43.3 µM 1.37E-9 mitochondrial stress 5 1.02E-14 0.05
18 SGTC_1827 berberine 7.35 7.2 µM 5.40E-9 60S ribosome export 4 9.66E-14 1.28
19 SGTC_1991 st073000 7.30 8.9 µM 6.77E-9 NEO1 4 1.40E-13 0.09
20 SGTC_2129 girgensonine 7.28 121.0 µM 7.70E-9 heme biosynthesis & mitochondrial translocase 7 1.73E-13 0.30

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.558 1.64E-273 YOL144W NOP8 het Nucleolar protein required for 60S ribosomal subunit biogenesis
0.305 4.06E-73 YCR052W RSC6 het Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p
0.295 4.44E-68 YCR035C RRP43 het Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp43p (OIP2, EXOSC8); protein abundance increases in response to DNA replication stress
0.293 3.27E-67 YNL267W PIK1 het Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton
0.270 6.26E-57 YOR115C TRS33 hom One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic
0.252 1.09E-49 YOR070C GYP1 hom Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
0.243 2.12E-46 YML037C_p YML037C_p hom Putative protein of unknown function with some characteristics of a transcriptional activator; may be a target of Dbf2p-Mob1p kinase; GFP-fusion protein co-localizes with clathrin-coated vesicles; YML037C is not an essential gene
0.234 4.96E-43 YDR317W HIM1 hom Protein of unknown function involved in DNA repair
0.225 1.28E-39 YMR134W ERG29 het Protein of unknown function that may be involved in iron metabolism; mutant bm-8 has a growth defect on iron-limited medium that is complemented by overexpression of Yfh1p; shows localization to the ER; highly conserved in ascomycetes
0.220 3.71E-38 YDL133W SRF1 hom Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that accumulates intraneuronally in Alzheimer's patients
0.213 1.46E-35 YDR084C TVP23 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
0.212 3.02E-35 YJL204C RCY1 hom F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth
0.205 5.03E-33 YER031C YPT31 hom Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication
0.203 2.28E-32 YPR091C NVJ2 hom Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ); may be involved in sterol metabolism or signaling at the NVJ; contains a synaptotagmin-like-mitochondrial- lipid binding protein (SMP) domain; binds phosphatidylinositols and other lipids in a large-scale study; may interact with ribosomes, based on co-purification experiments
0.196 2.57E-30 YOR039W CKB2 hom Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase