YJL143W / TIM17

Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex

Zygosity: Heterozygous strain
fixedexpanded
Profile for YJL143W / TIM17

Click on Significant Values for Screen Details ID:SGTC_35|Compound:0133-0054|FD-Score:3.58|P-value:1.41E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:5.13|P-value:9.64E-8 ID:SGTC_73|Compound:0327-0325|FD-Score:-3.42|P-value:2.27E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:5.06|P-value:1.40E-7 ID:SGTC_135|Compound:0933-0004|FD-Score:3.20|P-value:5.98E-4 ID:SGTC_141|Compound:0443-0274|FD-Score:-8.56|P-value:1.05E-18 ID:SGTC_163|Compound:1327-0036|FD-Score:-4.74|P-value:6.17E-7 ID:SGTC_165|Compound:k038-0023|FD-Score:-4.35|P-value:4.14E-6 ID:SGTC_180|Compound:1486-1293|FD-Score:3.08|P-value:9.08E-4 ID:SGTC_188|Compound:3229-0966|FD-Score:4.72|P-value:8.36E-7 ID:SGTC_193|Compound:1273-0060|FD-Score:-3.13|P-value:6.55E-4 ID:SGTC_195|Compound:4234-0266|FD-Score:-3.19|P-value:5.34E-4 ID:SGTC_208|Compound:k072-0098|FD-Score:-4.96|P-value:1.90E-7 ID:SGTC_211|Compound:3455-0679|FD-Score:5.30|P-value:3.58E-8 ID:SGTC_372|Compound:0155-0182|FD-Score:-3.35|P-value:2.96E-4 ID:SGTC_373|Compound:0844-0104|FD-Score:5.88|P-value:1.12E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:-3.82|P-value:4.51E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:4.34|P-value:5.18E-6 ID:SGTC_490|Compound:phenamil|FD-Score:-5.19|P-value:5.42E-8 ID:SGTC_496|Compound:calpeptin|FD-Score:3.40|P-value:2.81E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:-3.37|P-value:2.73E-4 ID:SGTC_547|Compound:1120-0019|FD-Score:-3.76|P-value:5.91E-5 ID:SGTC_568|Compound:1193-0097|FD-Score:7.65|P-value:3.70E-15 ID:SGTC_607|Compound:4491-0986|FD-Score:-3.89|P-value:3.39E-5 ID:SGTC_674|Compound:0498-0004|FD-Score:-7.05|P-value:2.84E-13 ID:SGTC_680|Compound:0417-1641|FD-Score:-3.07|P-value:8.19E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:3.68|P-value:9.38E-5 ID:SGTC_778|Compound:3456-2434|FD-Score:-4.12|P-value:1.21E-5 ID:SGTC_834|Compound:0312-0008|FD-Score:3.17|P-value:6.53E-4 ID:SGTC_842|Compound:0271-0008|FD-Score:-3.33|P-value:3.18E-4 ID:SGTC_902|Compound:1120-0002|FD-Score:-3.54|P-value:1.41E-4 ID:SGTC_942|Compound:3253-1115|FD-Score:3.74|P-value:7.30E-5 ID:SGTC_945|Compound:3381-0768|FD-Score:3.13|P-value:7.48E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:-3.50|P-value:1.67E-4 ID:SGTC_966|Compound:1300-0360|FD-Score:-3.43|P-value:2.18E-4 ID:SGTC_969|Compound:1313-0238|FD-Score:-3.60|P-value:1.12E-4 ID:SGTC_977|Compound:1348-1378|FD-Score:-3.09|P-value:7.64E-4 ID:SGTC_1036|Compound:k216-0215|FD-Score:-3.63|P-value:9.91E-5 ID:SGTC_1044|Compound:1222-0021|FD-Score:-3.02|P-value:9.85E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:4.18|P-value:1.11E-5 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.90|P-value:3.24E-7 ID:SGTC_1232|Compound:0279-0259|FD-Score:3.13|P-value:7.55E-4 ID:SGTC_1240|Compound:0356-0016|FD-Score:4.43|P-value:3.45E-6 ID:SGTC_1278|Compound:0874-0585|FD-Score:3.86|P-value:4.48E-5 ID:SGTC_1301|Compound:naphtanilide LB|FD-Score:-3.50|P-value:1.65E-4 ID:SGTC_1310|Compound:1188-0297|FD-Score:-4.21|P-value:8.13E-6 ID:SGTC_1347|Compound:1493-0251|FD-Score:-5.85|P-value:1.08E-9 ID:SGTC_1353|Compound:1498-1206|FD-Score:-6.31|P-value:5.27E-11 ID:SGTC_1378|Compound:2093-0007|FD-Score:3.53|P-value:1.74E-4 ID:SGTC_1453|Compound:4237-0541|FD-Score:-3.69|P-value:7.82E-5 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.34|P-value:3.54E-4 ID:SGTC_1750|Compound:st081859|FD-Score:3.60|P-value:1.29E-4 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:-3.86|P-value:3.79E-5 ID:SGTC_1852|Compound:st056254|FD-Score:3.84|P-value:4.88E-5 ID:SGTC_1900|Compound:st060200|FD-Score:8.79|P-value:1.83E-19 ID:SGTC_1901|Compound:st060216|FD-Score:5.49|P-value:1.24E-8 ID:SGTC_1902|Compound:st060212|FD-Score:5.95|P-value:7.23E-10 ID:SGTC_1903|Compound:st060211|FD-Score:5.31|P-value:3.42E-8 ID:SGTC_1904|Compound:st060225|FD-Score:4.79|P-value:5.69E-7 ID:SGTC_1905|Compound:st060207|FD-Score:4.70|P-value:8.99E-7 ID:SGTC_2021|Compound:4019055|FD-Score:3.77|P-value:6.59E-5 ID:SGTC_2050|Compound:5263056|FD-Score:8.33|P-value:1.22E-17 ID:SGTC_2054|Compound:5233173|FD-Score:-8.92|P-value:4.06E-20 ID:SGTC_2241|Compound:6772625|FD-Score:-5.39|P-value:1.70E-8 ID:SGTC_2260|Compound:7964312|FD-Score:3.62|P-value:1.19E-4 ID:SGTC_2362|Compound:9071156|FD-Score:3.25|P-value:4.93E-4 ID:SGTC_2368|Compound:9071271|FD-Score:3.06|P-value:9.52E-4 ID:SGTC_2418|Compound:pentamidine|FD-Score:-3.44|P-value:2.11E-4 ID:SGTC_2536|Compound:dehydroabietamide|FD-Score:3.59|P-value:1.34E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-3.44|P-value:2.12E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:-4.61|P-value:1.20E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:-3.75|P-value:6.15E-5 ID:SGTC_2659|Compound:sanguinarine|FD-Score:-3.93|P-value:2.83E-5 ID:SGTC_2668|Compound:2',4'-dihydroxychalcone|FD-Score:-3.14|P-value:6.36E-4 ID:SGTC_2704|Compound:st078022|FD-Score:4.11|P-value:1.55E-5 ID:SGTC_2739|Compound:tacrine|FD-Score:-4.20|P-value:8.53E-6 ID:SGTC_2792|Compound:7535235|FD-Score:3.07|P-value:9.48E-4 ID:SGTC_2838|Compound:9002687|FD-Score:4.86|P-value:3.89E-7 ID:SGTC_2880|Compound:9042983|FD-Score:3.27|P-value:4.67E-4 ID:SGTC_2887|Compound:9044784|FD-Score:3.59|P-value:1.35E-4 ID:SGTC_2965|Compound:9082772|FD-Score:-5.19|P-value:5.36E-8 ID:SGTC_2967|Compound:9089538|FD-Score:3.05|P-value:9.91E-4 ID:SGTC_2980|Compound:9014342|FD-Score:-5.42|P-value:1.45E-8 ID:SGTC_2986|Compound:9022445|FD-Score:3.18|P-value:6.26E-4 ID:SGTC_3026|Compound:9090633|FD-Score:-3.16|P-value:5.86E-4 ID:SGTC_3062|Compound:9077494|FD-Score:-4.28|P-value:5.72E-6 ID:SGTC_3081|Compound:9117243|FD-Score:4.49|P-value:2.56E-6 ID:SGTC_3105|Compound:9121040|FD-Score:3.47|P-value:2.13E-4 ID:SGTC_3126|Compound:9127922|FD-Score:5.40|P-value:2.04E-8 ID:SGTC_3202|Compound:9113761|FD-Score:3.30|P-value:4.06E-4 ID:SGTC_35|Compound:0133-0054|FD-Score:3.58|P-value:1.41E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:5.13|P-value:9.64E-8 ID:SGTC_73|Compound:0327-0325|FD-Score:-3.42|P-value:2.27E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:5.06|P-value:1.40E-7 ID:SGTC_135|Compound:0933-0004|FD-Score:3.20|P-value:5.98E-4 ID:SGTC_141|Compound:0443-0274|FD-Score:-8.56|P-value:1.05E-18 ID:SGTC_163|Compound:1327-0036|FD-Score:-4.74|P-value:6.17E-7 ID:SGTC_165|Compound:k038-0023|FD-Score:-4.35|P-value:4.14E-6 ID:SGTC_180|Compound:1486-1293|FD-Score:3.08|P-value:9.08E-4 ID:SGTC_188|Compound:3229-0966|FD-Score:4.72|P-value:8.36E-7 ID:SGTC_193|Compound:1273-0060|FD-Score:-3.13|P-value:6.55E-4 ID:SGTC_195|Compound:4234-0266|FD-Score:-3.19|P-value:5.34E-4 ID:SGTC_208|Compound:k072-0098|FD-Score:-4.96|P-value:1.90E-7 ID:SGTC_211|Compound:3455-0679|FD-Score:5.30|P-value:3.58E-8 ID:SGTC_372|Compound:0155-0182|FD-Score:-3.35|P-value:2.96E-4 ID:SGTC_373|Compound:0844-0104|FD-Score:5.88|P-value:1.12E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:-3.82|P-value:4.51E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:4.34|P-value:5.18E-6 ID:SGTC_490|Compound:phenamil|FD-Score:-5.19|P-value:5.42E-8 ID:SGTC_496|Compound:calpeptin|FD-Score:3.40|P-value:2.81E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:-3.37|P-value:2.73E-4 ID:SGTC_547|Compound:1120-0019|FD-Score:-3.76|P-value:5.91E-5 ID:SGTC_568|Compound:1193-0097|FD-Score:7.65|P-value:3.70E-15 ID:SGTC_607|Compound:4491-0986|FD-Score:-3.89|P-value:3.39E-5 ID:SGTC_674|Compound:0498-0004|FD-Score:-7.05|P-value:2.84E-13 ID:SGTC_680|Compound:0417-1641|FD-Score:-3.07|P-value:8.19E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:3.68|P-value:9.38E-5 ID:SGTC_778|Compound:3456-2434|FD-Score:-4.12|P-value:1.21E-5 ID:SGTC_834|Compound:0312-0008|FD-Score:3.17|P-value:6.53E-4 ID:SGTC_842|Compound:0271-0008|FD-Score:-3.33|P-value:3.18E-4 ID:SGTC_902|Compound:1120-0002|FD-Score:-3.54|P-value:1.41E-4 ID:SGTC_942|Compound:3253-1115|FD-Score:3.74|P-value:7.30E-5 ID:SGTC_945|Compound:3381-0768|FD-Score:3.13|P-value:7.48E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:-3.50|P-value:1.67E-4 ID:SGTC_966|Compound:1300-0360|FD-Score:-3.43|P-value:2.18E-4 ID:SGTC_969|Compound:1313-0238|FD-Score:-3.60|P-value:1.12E-4 ID:SGTC_977|Compound:1348-1378|FD-Score:-3.09|P-value:7.64E-4 ID:SGTC_1036|Compound:k216-0215|FD-Score:-3.63|P-value:9.91E-5 ID:SGTC_1044|Compound:1222-0021|FD-Score:-3.02|P-value:9.85E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:4.18|P-value:1.11E-5 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.90|P-value:3.24E-7 ID:SGTC_1232|Compound:0279-0259|FD-Score:3.13|P-value:7.55E-4 ID:SGTC_1240|Compound:0356-0016|FD-Score:4.43|P-value:3.45E-6 ID:SGTC_1278|Compound:0874-0585|FD-Score:3.86|P-value:4.48E-5 ID:SGTC_1301|Compound:naphtanilide LB|FD-Score:-3.50|P-value:1.65E-4 ID:SGTC_1310|Compound:1188-0297|FD-Score:-4.21|P-value:8.13E-6 ID:SGTC_1347|Compound:1493-0251|FD-Score:-5.85|P-value:1.08E-9 ID:SGTC_1353|Compound:1498-1206|FD-Score:-6.31|P-value:5.27E-11 ID:SGTC_1378|Compound:2093-0007|FD-Score:3.53|P-value:1.74E-4 ID:SGTC_1453|Compound:4237-0541|FD-Score:-3.69|P-value:7.82E-5 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.34|P-value:3.54E-4 ID:SGTC_1750|Compound:st081859|FD-Score:3.60|P-value:1.29E-4 ID:SGTC_1785|Compound:bathophenanthroline|FD-Score:-3.86|P-value:3.79E-5 ID:SGTC_1852|Compound:st056254|FD-Score:3.84|P-value:4.88E-5 ID:SGTC_1900|Compound:st060200|FD-Score:8.79|P-value:1.83E-19 ID:SGTC_1901|Compound:st060216|FD-Score:5.49|P-value:1.24E-8 ID:SGTC_1902|Compound:st060212|FD-Score:5.95|P-value:7.23E-10 ID:SGTC_1903|Compound:st060211|FD-Score:5.31|P-value:3.42E-8 ID:SGTC_1904|Compound:st060225|FD-Score:4.79|P-value:5.69E-7 ID:SGTC_1905|Compound:st060207|FD-Score:4.70|P-value:8.99E-7 ID:SGTC_2021|Compound:4019055|FD-Score:3.77|P-value:6.59E-5 ID:SGTC_2050|Compound:5263056|FD-Score:8.33|P-value:1.22E-17 ID:SGTC_2054|Compound:5233173|FD-Score:-8.92|P-value:4.06E-20 ID:SGTC_2241|Compound:6772625|FD-Score:-5.39|P-value:1.70E-8 ID:SGTC_2260|Compound:7964312|FD-Score:3.62|P-value:1.19E-4 ID:SGTC_2362|Compound:9071156|FD-Score:3.25|P-value:4.93E-4 ID:SGTC_2368|Compound:9071271|FD-Score:3.06|P-value:9.52E-4 ID:SGTC_2418|Compound:pentamidine|FD-Score:-3.44|P-value:2.11E-4 ID:SGTC_2536|Compound:dehydroabietamide|FD-Score:3.59|P-value:1.34E-4 ID:SGTC_2541|Compound:muurolladie-3-one|FD-Score:-3.44|P-value:2.12E-4 ID:SGTC_2645|Compound:abamectin|FD-Score:-4.61|P-value:1.20E-6 ID:SGTC_2651|Compound:1327-0036|FD-Score:-3.75|P-value:6.15E-5 ID:SGTC_2659|Compound:sanguinarine|FD-Score:-3.93|P-value:2.83E-5 ID:SGTC_2668|Compound:2',4'-dihydroxychalcone|FD-Score:-3.14|P-value:6.36E-4 ID:SGTC_2704|Compound:st078022|FD-Score:4.11|P-value:1.55E-5 ID:SGTC_2739|Compound:tacrine|FD-Score:-4.20|P-value:8.53E-6 ID:SGTC_2792|Compound:7535235|FD-Score:3.07|P-value:9.48E-4 ID:SGTC_2838|Compound:9002687|FD-Score:4.86|P-value:3.89E-7 ID:SGTC_2880|Compound:9042983|FD-Score:3.27|P-value:4.67E-4 ID:SGTC_2887|Compound:9044784|FD-Score:3.59|P-value:1.35E-4 ID:SGTC_2965|Compound:9082772|FD-Score:-5.19|P-value:5.36E-8 ID:SGTC_2967|Compound:9089538|FD-Score:3.05|P-value:9.91E-4 ID:SGTC_2980|Compound:9014342|FD-Score:-5.42|P-value:1.45E-8 ID:SGTC_2986|Compound:9022445|FD-Score:3.18|P-value:6.26E-4 ID:SGTC_3026|Compound:9090633|FD-Score:-3.16|P-value:5.86E-4 ID:SGTC_3062|Compound:9077494|FD-Score:-4.28|P-value:5.72E-6 ID:SGTC_3081|Compound:9117243|FD-Score:4.49|P-value:2.56E-6 ID:SGTC_3105|Compound:9121040|FD-Score:3.47|P-value:2.13E-4 ID:SGTC_3126|Compound:9127922|FD-Score:5.40|P-value:2.04E-8 ID:SGTC_3202|Compound:9113761|FD-Score:3.30|P-value:4.06E-4

Top fitness defect scores for YJL143W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1900 st060200 8.79 72.8 µM 1.83E-19 1 7.23E-19 2.54
2 SGTC_2050 5263056 8.33 171.0 µM 1.22E-17 fatty acid desaturase (OLE1) 7 4.14E-17 0.69
3 SGTC_568 1193-0097 7.65 7.5 µM 3.70E-15 ERAD & cell cycle 6 1.03E-14 0.14
4 SGTC_1902 st060212 5.95 70.5 µM 7.23E-10 1 1.31E-9 0.98
5 SGTC_373 0844-0104 5.88 25.9 µM 1.12E-9 ERAD & cell cycle 4 2.01E-9 0.52
6 SGTC_1901 st060216 5.49 58.6 µM 1.24E-8 1 2.05E-8 1.06
7 SGTC_3126 9127922 5.40 49.5 µM 2.04E-8 fatty acid desaturase (OLE1) 13 3.32E-8 0.14
8 SGTC_1903 st060211 5.31 78.3 µM 3.42E-8 1 5.45E-8 1.39
9 SGTC_211 3455-0679 5.30 143.5 µM 3.58E-8 5 5.70E-8 0.41
10 SGTC_41 0478-0632 5.13 82.6 µM 9.64E-8 7 1.49E-7 0.14
11 SGTC_103 0844-0104 5.06 51.8 µM 1.40E-7 ERAD & cell cycle 36 2.13E-7 0.15
12 SGTC_1230 0170-0365 4.90 3.8 µM 3.24E-7 endomembrane recycling 15 4.79E-7 0.10
13 SGTC_2838 9002687 4.86 71.4 µM 3.89E-7 fatty acid desaturase (OLE1) 8 5.73E-7 0.03
14 SGTC_1904 st060225 4.79 78.0 µM 5.69E-7 2 8.27E-7 0.53
15 SGTC_188 3229-0966 4.72 278.5 µM 8.36E-7 13 1.20E-6 0.20
16 SGTC_1905 st060207 4.70 84.5 µM 8.99E-7 1 1.29E-6 0.51
17 SGTC_3081 9117243 4.49 49.5 µM 2.56E-6 fatty acid desaturase (OLE1) 22 3.54E-6 0.12
18 SGTC_1240 0356-0016 4.43 42.1 µM 3.45E-6 mitochondrial response to ROS 3 4.72E-6 0.17
19 SGTC_453 enantio-paf c16 4.34 10.0 µM 5.18E-6 19 6.99E-6 0.09
20 SGTC_1161 k007-0610 4.18 110.0 µM 1.11E-5 ERAD & cell cycle 39 1.47E-5 0.01

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.266 1.43E-55 YNR017W TIM23 het Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel
0.249 1.21E-48 YDR478W SNM1 het Subunit of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP
0.212 2.36E-35 YGL055W OLE1 het Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
0.210 6.22E-35 YGL116W CDC20 het Activator of anaphase-promoting complex/cyclosome (APC/C); APC/C is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; cell-cycle regulated; potential Cdc28p substrate; relative distribution to the nucleus increases upon DNA replication stress
0.208 3.21E-34 YER171W RAD3 het 5' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress
0.202 4.60E-32 YCR093W CDC39 het Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
0.201 8.90E-32 YHL015W RPS20 het Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; homologous to mammalian ribosomal protein S20 and bacterial S10
0.194 9.46E-30 YIL030C SSM4 hom Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation
0.192 4.05E-29 YDL060W TSR1 het Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p; relocalizes from nucleus to cytoplasm upon DNA replication stress
0.182 2.57E-26 YDL148C NOP14 het Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA
0.175 1.56E-24 YDL226C GCS1 hom ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
0.172 1.27E-23 YHR166C CDC23 het Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
0.172 1.34E-23 YOL065C INP54 hom Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
0.166 3.89E-22 YBR029C CDS1 het Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids
0.165 7.32E-22 YJR123W RPS5 het Protein component of the small (40S) ribosomal subunit; least basic of non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; homologous to mammalian ribosomal protein S5 and bacterial S7