Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP)
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YJR044C deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Correlation | pval | ORF | Gene | Zygosity | Description |
---|---|---|---|---|---|
0.109 | 2.70E-10 | YGL192W | IME4 | hom | Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid cells; haploids repress IME4 transcription via production of antisense IME4 transcripts; antisense transcription is repressed in diploids |
0.102 | 3.06E-9 | YMR136W | GAT2 | hom | Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine |
0.099 | 7.86E-9 | YOL153C | YOL153C | hom | Hypothetical protein |
0.097 | 1.65E-8 | YOR282W_d | YOR282W_d | het | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps essential, verified gene PLP2/YOR281C |
0.089 | 2.54E-7 | YCL049C_p | YCL049C_p | hom | Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene |
0.088 | 2.96E-7 | YGR269W_d | YGR269W_d | hom | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF HUA1/YGR268C |
0.088 | 3.69E-7 | YML080W | DUS1 | hom | Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17 |
0.086 | 5.80E-7 | YGR017W_p | YGR017W_p | hom | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm |
0.086 | 6.09E-7 | YFR031C-A | RPL2A | hom | Ribosomal 60S subunit protein L2A; homologous to mammalian ribosomal protein L2 and bacterial L2; RPL2A has a paralog, RPL2B, that arose from the whole genome duplication |
0.083 | 1.62E-6 | YPL114W_d | YPL114W_d | hom | Dubious open reading frame, unlikely to encode a functional protein; largely overlaps ORF YPL113C; diploid deletion in BY4743 strain background exhibits high budding index |
0.082 | 1.97E-6 | YLR184W_d | YLR184W_d | hom | Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data |
0.082 | 2.20E-6 | YPR002W | PDH1 | hom | Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate |
0.080 | 3.31E-6 | YJL163C_p | YJL163C_p | hom | Putative protein of unknown function |
0.078 | 5.49E-6 | YHR190W | ERG9 | het | Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway |
0.075 | 1.37E-5 | YJL042W | MHP1 | hom | Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins |