| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|
| 0.113 |
6.29E-11 |
YPL074W |
YTA6 |
hom |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress |
| 0.108 |
2.89E-10 |
YMR074C |
YMR074C |
hom |
Protein with homology to human PDCD5; PDCD5 is involved in programmed cell death; N-terminal region forms a conserved triple-helix bundle structure; overexpression promotes H2O2-induced apoptosis; YMR074C is not an essential gene; protein abundance increases in response to DNA replication stress |
| 0.103 |
2.12E-9 |
YDR169C-A_p |
YDR169C-A_p |
hom |
Putative protein of unknown function; identified by fungal homology and RT-PCR |
| 0.102 |
3.73E-9 |
YER047C |
SAP1 |
hom |
Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system |
| 0.097 |
1.53E-8 |
YNL118C |
DCP2 |
het |
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex; removes the 5' cap structure from mRNAs prior to their degradation; nudix hydrolase family member; forms cytoplasmic foci upon DNA replication stress |
| 0.097 |
1.96E-8 |
YDR217C |
RAD9 |
hom |
DNA damage-dependent checkpoint protein; required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; multiple cyclin dependent kinase consensus sites and the C-terminal BRCT domain contribute to DNA damage checkpoint activation; potential Cdc28p substrate |
| 0.094 |
5.35E-8 |
YKL174C |
TPO5 |
hom |
Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles |
| 0.093 |
6.00E-8 |
YDR526C_d |
YDR526C_d |
het |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
| 0.092 |
1.04E-7 |
YDR409W |
SIZ1 |
hom |
SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring |
| 0.091 |
1.12E-7 |
YDR191W |
HST4 |
hom |
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism |
| 0.090 |
1.76E-7 |
YDL141W |
BPL1 |
het |
Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation |
| 0.089 |
2.63E-7 |
YDR210W_p |
YDR210W_p |
hom |
Predicted tail-anchored plasma membrane protein containing a conserved CYSTM module; related proteins in other organisms may be involved in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery |
| 0.087 |
4.35E-7 |
YPL053C |
KTR6 |
hom |
Probable mannosylphosphate transferase; involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family; KTR6 has a paralog, KRE2, that arose from the whole genome duplication |
| 0.086 |
5.79E-7 |
YHL021C |
AIM17 |
hom |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss |
| 0.084 |
9.71E-7 |
YNL130C |
CPT1 |
hom |
Cholinephosphotransferase; required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription; CPT1 has a paralog, EPT1, that arose from the whole genome duplication |
