Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.204 |
8.44E-33 |
YHR003C |
YHR003C |
hom |
Protein of unknown function, localized to the mitochondrial outer membrane |
0.202 |
3.61E-32 |
YMR210W |
YMR210W |
hom |
Putative acyltransferase with similarity to Eeb1p and Eht1p, has a minor role in medium-chain fatty acid ethyl ester biosynthesis; may be involved in lipid metabolism and detoxification |
0.193 |
1.73E-29 |
YML083C |
YML083C |
hom |
Protein of unknown function; transcriptionally regulated by Upc2p via an upstream sterol response element; strong increase in transcript abundance during anaerobic growth compared to aerobic growth; cells deleted for YML083C do not exhibit growth defects in anerobic or anaerobic conditions |
0.188 |
3.80E-28 |
YNL260C |
LTO1 |
het |
Essential protein that forms a complex with Rli1p and Yae1p; ortholog of human ORAOV1, which is overexpressed in solid tumors; inviability of null mutant under standard conditions is complemented by overexpression of ORAOV1; essential for growth under standard (aerobic) conditions but not under anaerobic conditions; may have a role in protection of ribosomal assembly and function from damage due to reactive oxygen species |
0.186 |
1.21E-27 |
YNL312W |
RFA2 |
het |
Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; protein abundance increases in response to DNA replication stress |
0.154 |
3.18E-19 |
YGL114W_p |
YGL114W_p |
hom |
Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters |
0.151 |
1.52E-18 |
YLR317W_d |
YLR317W_d |
het |
Dubious open reading frame; may be part of a bicistronic transcript with NKP2/YLR315W; overlaps the verified ORF TAD3/YLR316C |
0.147 |
1.27E-17 |
YOR271C_p |
FSF1_p |
hom |
Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis |
0.145 |
3.28E-17 |
YDR056C_p |
YDR056C_p |
hom |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR056C is not an essential protein |
0.145 |
3.56E-17 |
YKL001C |
MET14 |
hom |
Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism |
0.142 |
1.44E-16 |
YER056C |
FCY2 |
hom |
Purine-cytosine permease; mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; relative distribution to the vacuole increases upon DNA replication stress |
0.141 |
1.93E-16 |
YLL046C |
RNP1 |
hom |
Ribonucleoprotein that contains two RNA recognition motifs (RRM) |
0.141 |
2.29E-16 |
YMR111C |
YMR111C |
hom |
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR111C is not an essential gene; forms nuclear foci upon DNA replication stress |
0.139 |
6.28E-16 |
YML116W-A_d |
YML116W-A_d |
hom |
Putative protein of unknown function |
0.137 |
1.87E-15 |
YML131W |
YML131W |
hom |
Protein of unknown function; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress |