Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.081 |
2.37E-6 |
YPL245W_p |
YPL245W_p |
hom |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm |
0.077 |
8.64E-6 |
YER087W |
AIM10 |
hom |
Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays elevated frequency of mitochondrial genome loss |
0.069 |
5.85E-5 |
YMR175W-A_p |
YMR175W-A_p |
hom |
Putative protein of unknown function |
0.068 |
8.90E-5 |
YIL034C |
CAP2 |
hom |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress |
0.067 |
1.15E-4 |
YPR003C_p |
YPR003C_p |
hom |
Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene |
0.065 |
1.72E-4 |
YBL054W |
TOD6 |
hom |
PAC motif binding protein involved in rRNA and ribosome biogenesis; subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor; hypophosphorylated by rapamycin treatment in a Sch9p-dependent manner; TOD6 has a paralog, DOT6, that arose from the whole genome duplication |
0.064 |
2.05E-4 |
YPL221W |
FLC1 |
hom |
Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance |
0.064 |
2.08E-4 |
YIL007C |
NAS2 |
hom |
Proteasome-interacting protein; involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); similar to mammalian proteasomal modulator subunit; non-essential gene; interacts with Rpn4p; protein abundance increases in response to DNA replication stress |
0.061 |
4.07E-4 |
YLR453C |
RIF2 |
hom |
Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation |
0.060 |
4.95E-4 |
YNL292W |
PUS4 |
hom |
Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype) |
0.060 |
5.15E-4 |
YDL012C |
YDL012C |
hom |
Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication |
0.060 |
5.34E-4 |
YNL212W |
VID27 |
hom |
Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth |
0.060 |
5.58E-4 |
YIL123W |
SIM1 |
hom |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated |
0.059 |
5.82E-4 |
YLR368W |
MDM30 |
hom |
F-box component of an SCF ubiquitin protein ligase complex; associates with and is required for Fzo1p ubiquitination and for mitochondria fusion; stimulates nuclear export of specific mRNAs; promotes ubiquitin-mediated degradation of Gal4p in some strains |
0.059 |
5.92E-4 |
YMR010W_p |
YMR010W_p |
hom |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR010W is not an essential gene; YMR010W mRNA is transcribed with ADI1 |