YLR033W / RSC58

Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance

Zygosity: Heterozygous strain
fixedexpanded
Profile for YLR033W / RSC58

Click on Significant Values for Screen Details ID:SGTC_22|Compound:0964-0034|FD-Score:5.59|P-value:6.10E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:8.41|P-value:5.94E-7 ID:SGTC_64|Compound:000l-0018|FD-Score:19.30|P-value:4.08E-29 ID:SGTC_67|Compound:0335-0847|FD-Score:5.44|P-value:8.28E-4 ID:SGTC_69|Compound:0096-0274|FD-Score:6.27|P-value:1.44E-4 ID:SGTC_93|Compound:0109-0045|FD-Score:6.17|P-value:1.80E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:6.16|P-value:1.85E-4 ID:SGTC_138|Compound:0850-0259|FD-Score:8.23|P-value:9.91E-7 ID:SGTC_145|Compound:3737-0113|FD-Score:6.46|P-value:9.41E-5 ID:SGTC_157|Compound:1348-1695|FD-Score:12.80|P-value:9.29E-14 ID:SGTC_177|Compound:1327-0068|FD-Score:23.10|P-value:1.07E-40 ID:SGTC_181|Compound:1447-1644|FD-Score:6.58|P-value:7.09E-5 ID:SGTC_203|Compound:k066-0004|FD-Score:11.60|P-value:1.12E-11 ID:SGTC_227|Compound:fluconazole|FD-Score:8.25|P-value:9.38E-7 ID:SGTC_248|Compound:streptozotocin|FD-Score:8.15|P-value:1.25E-6 ID:SGTC_257|Compound:daunorubicin|FD-Score:14.20|P-value:1.10E-16 ID:SGTC_262|Compound:fenpropimorph|FD-Score:5.87|P-value:3.43E-4 ID:SGTC_267|Compound:4-Nitroquinoline-1-oxide  (4-NQO)|FD-Score:5.67|P-value:5.20E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:15.30|P-value:5.36E-19 ID:SGTC_272|Compound:doxorubicin|FD-Score:10.30|P-value:1.33E-9 ID:SGTC_273|Compound:hydroxyurea|FD-Score:7.61|P-value:5.45E-6 ID:SGTC_288|Compound:1315-0019|FD-Score:9.97|P-value:4.23E-9 ID:SGTC_319|Compound:1348-1596|FD-Score:7.29|P-value:1.24E-5 ID:SGTC_322|Compound:k048-0136|FD-Score:8.30|P-value:8.10E-7 ID:SGTC_324|Compound:1315-0088|FD-Score:10.20|P-value:1.89E-9 ID:SGTC_329|Compound:k048-0121|FD-Score:10.40|P-value:8.15E-10 ID:SGTC_331|Compound:k048-0133|FD-Score:8.74|P-value:2.26E-7 ID:SGTC_342|Compound:k048-0088|FD-Score:7.58|P-value:5.88E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:7.70|P-value:4.33E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:7.19|P-value:1.61E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:16.60|P-value:6.06E-22 ID:SGTC_520|Compound:3584-0023|FD-Score:6.20|P-value:1.68E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:15.10|P-value:1.36E-18 ID:SGTC_557|Compound:1315-0110|FD-Score:5.89|P-value:3.31E-4 ID:SGTC_566|Compound:0958-0068|FD-Score:12.00|P-value:2.66E-12 ID:SGTC_576|Compound:1073-0113|FD-Score:6.59|P-value:7.00E-5 ID:SGTC_580|Compound:1123-0028|FD-Score:5.68|P-value:5.06E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:9.41|P-value:2.76E-8 ID:SGTC_590|Compound:k048-0076|FD-Score:6.52|P-value:8.19E-5 ID:SGTC_632|Compound:0781-2353|FD-Score:7.27|P-value:1.33E-5 ID:SGTC_642|Compound:0335-0876|FD-Score:6.58|P-value:7.18E-5 ID:SGTC_643|Compound:k048-0106|FD-Score:22.70|P-value:2.02E-39 ID:SGTC_651|Compound:3253-0966|FD-Score:-5.59|P-value:6.83E-4 ID:SGTC_666|Compound:0272-0154|FD-Score:7.83|P-value:3.03E-6 ID:SGTC_673|Compound:1082-0474|FD-Score:17.60|P-value:1.71E-24 ID:SGTC_709|Compound:3807-1509|FD-Score:18.20|P-value:4.85E-26 ID:SGTC_746|Compound:1095-0025|FD-Score:6.15|P-value:1.88E-4 ID:SGTC_783|Compound:0848-0141|FD-Score:18.10|P-value:6.98E-26 ID:SGTC_788|Compound:1182-0090|FD-Score:7.56|P-value:6.17E-6 ID:SGTC_794|Compound:k038-0031|FD-Score:5.35|P-value:9.74E-4 ID:SGTC_818|Compound:4072-2707|FD-Score:5.75|P-value:4.35E-4 ID:SGTC_825|Compound:1988-2224|FD-Score:12.60|P-value:1.86E-13 ID:SGTC_829|Compound:1635-0120|FD-Score:10.70|P-value:2.86E-10 ID:SGTC_839|Compound:0122-0028|FD-Score:5.88|P-value:3.33E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:13.40|P-value:5.67E-15 ID:SGTC_885|Compound:0865-0106|FD-Score:7.61|P-value:5.43E-6 ID:SGTC_916|Compound:4466-0038|FD-Score:10.80|P-value:2.23E-10 ID:SGTC_928|Compound:2764-0428|FD-Score:10.70|P-value:3.70E-10 ID:SGTC_951|Compound:1171-0579|FD-Score:7.94|P-value:2.22E-6 ID:SGTC_964|Compound:1287-0107|FD-Score:5.73|P-value:4.59E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:15.70|P-value:5.36E-20 ID:SGTC_984|Compound:1492-0255|FD-Score:5.94|P-value:2.93E-4 ID:SGTC_1026|Compound:k007-1105|FD-Score:6.27|P-value:1.45E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:7.80|P-value:3.27E-6 ID:SGTC_1090|Compound:efavirenz|FD-Score:6.95|P-value:2.92E-5 ID:SGTC_1098|Compound:clofazimine|FD-Score:9.06|P-value:8.45E-8 ID:SGTC_1133|Compound:3473-0247|FD-Score:18.20|P-value:4.34E-26 ID:SGTC_1168|Compound:k815-0004|FD-Score:6.20|P-value:1.68E-4 ID:SGTC_1171|Compound:0368-0077|FD-Score:6.48|P-value:8.88E-5 ID:SGTC_1229|Compound:0139-0193|FD-Score:6.13|P-value:1.98E-4 ID:SGTC_1239|Compound:0337-0584|FD-Score:11.20|P-value:5.38E-11 ID:SGTC_1269|Compound:0831-0796|FD-Score:-6.12|P-value:2.25E-4 ID:SGTC_1274|Compound:0865-0114|FD-Score:7.38|P-value:1.01E-5 ID:SGTC_1283|Compound:0922-0125|FD-Score:-5.79|P-value:4.57E-4 ID:SGTC_1311|Compound:1190-0148|FD-Score:7.71|P-value:4.21E-6 ID:SGTC_1371|Compound:2421-0008|FD-Score:7.62|P-value:5.28E-6 ID:SGTC_1374|Compound:2889-5571|FD-Score:15.10|P-value:1.37E-18 ID:SGTC_1396|Compound:3511-0007|FD-Score:7.72|P-value:4.03E-6 ID:SGTC_1446|Compound:4239-0190|FD-Score:8.32|P-value:7.74E-7 ID:SGTC_1453|Compound:4237-0541|FD-Score:6.52|P-value:8.18E-5 ID:SGTC_1493|Compound:4348-0038|FD-Score:8.54|P-value:4.10E-7 ID:SGTC_1522|Compound:st012842|FD-Score:-5.62|P-value:6.41E-4 ID:SGTC_1567|Compound:st069303|FD-Score:8.92|P-value:1.27E-7 ID:SGTC_1574|Compound:spiramycin|FD-Score:-5.79|P-value:4.53E-4 ID:SGTC_1584|Compound:6-fluoro-dl-tryptophan|FD-Score:5.55|P-value:6.54E-4 ID:SGTC_1651|Compound:st011928|FD-Score:7.21|P-value:1.54E-5 ID:SGTC_1652|Compound:st011932|FD-Score:23.70|P-value:9.92E-43 ID:SGTC_1672|Compound:st016598|FD-Score:5.37|P-value:9.49E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.10|P-value:8.30E-11 ID:SGTC_1696|Compound:st025591|FD-Score:5.36|P-value:9.53E-4 ID:SGTC_1707|Compound:st032323|FD-Score:8.57|P-value:3.67E-7 ID:SGTC_1722|Compound:st034304|FD-Score:16.00|P-value:1.22E-20 ID:SGTC_1723|Compound:st034307|FD-Score:10.10|P-value:2.50E-9 ID:SGTC_1731|Compound:st035964|FD-Score:9.21|P-value:5.18E-8 ID:SGTC_1773|Compound:st048542|FD-Score:5.98|P-value:2.73E-4 ID:SGTC_1800|Compound:st050079|FD-Score:5.74|P-value:4.45E-4 ID:SGTC_1831|Compound:st055328|FD-Score:7.18|P-value:1.66E-5 ID:SGTC_1844|Compound:rapamycin|FD-Score:9.65|P-value:1.28E-8 ID:SGTC_1868|Compound:st057644|FD-Score:5.67|P-value:5.19E-4 ID:SGTC_1870|Compound:st057514|FD-Score:10.30|P-value:1.35E-9 ID:SGTC_1875|Compound:nocodazole|FD-Score:8.88|P-value:1.47E-7 ID:SGTC_1884|Compound:5633444|FD-Score:11.70|P-value:8.19E-12 ID:SGTC_1898|Compound:st060199|FD-Score:5.50|P-value:7.28E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-5.58|P-value:7.01E-4 ID:SGTC_2041|Compound:5107442|FD-Score:8.09|P-value:1.50E-6 ID:SGTC_2056|Compound:5235370|FD-Score:-6.87|P-value:4.05E-5 ID:SGTC_2066|Compound:5222451|FD-Score:7.91|P-value:2.44E-6 ID:SGTC_2071|Compound:5230951|FD-Score:6.61|P-value:6.60E-5 ID:SGTC_2092|Compound:5303694|FD-Score:5.83|P-value:3.69E-4 ID:SGTC_2109|Compound:5483026|FD-Score:19.20|P-value:9.29E-29 ID:SGTC_2111|Compound:5486399|FD-Score:17.60|P-value:1.64E-24 ID:SGTC_2129|Compound:girgensonine|FD-Score:11.30|P-value:3.91E-11 ID:SGTC_2132|Compound:5317594|FD-Score:7.29|P-value:1.25E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:8.97|P-value:1.12E-7 ID:SGTC_2186|Compound:6124449|FD-Score:23.40|P-value:1.20E-41 ID:SGTC_2187|Compound:6125751|FD-Score:6.88|P-value:3.49E-5 ID:SGTC_2199|Compound:6590217|FD-Score:5.84|P-value:3.61E-4 ID:SGTC_2225|Compound:6654152|FD-Score:21.50|P-value:1.01E-35 ID:SGTC_2229|Compound:7354935|FD-Score:12.30|P-value:6.04E-13 ID:SGTC_2233|Compound:sulbentine|FD-Score:21.00|P-value:3.64E-34 ID:SGTC_2269|Compound:7935389|FD-Score:6.71|P-value:5.27E-5 ID:SGTC_2277|Compound:7947813|FD-Score:6.35|P-value:1.21E-4 ID:SGTC_2336|Compound:9001819|FD-Score:15.40|P-value:2.62E-19 ID:SGTC_2344|Compound:7990960|FD-Score:15.00|P-value:2.62E-18 ID:SGTC_2346|Compound:9031566|FD-Score:7.06|P-value:2.23E-5 ID:SGTC_2348|Compound:9022543|FD-Score:18.40|P-value:1.37E-26 ID:SGTC_2361|Compound:9034121|FD-Score:7.96|P-value:2.11E-6 ID:SGTC_2378|Compound:9074213|FD-Score:13.80|P-value:8.42E-16 ID:SGTC_2380|Compound:9035439|FD-Score:6.19|P-value:1.71E-4 ID:SGTC_2387|Compound:9077560|FD-Score:6.69|P-value:5.50E-5 ID:SGTC_2396|Compound:5342950|FD-Score:8.04|P-value:1.69E-6 ID:SGTC_2400|Compound:5203494|FD-Score:10.90|P-value:1.59E-10 ID:SGTC_2408|Compound:sulbentine|FD-Score:8.29|P-value:8.34E-7 ID:SGTC_2471|Compound:5466956|FD-Score:10.70|P-value:3.19E-10 ID:SGTC_2475|Compound:5812728|FD-Score:9.11|P-value:7.23E-8 ID:SGTC_2485|Compound:5633444|FD-Score:5.50|P-value:7.34E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:8.04|P-value:1.72E-6 ID:SGTC_2534|Compound:helenine|FD-Score:22.50|P-value:1.20E-38 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.36|P-value:9.56E-4 ID:SGTC_2575|Compound:plumbagin|FD-Score:7.26|P-value:1.35E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:7.92|P-value:2.38E-6 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:6.60|P-value:6.83E-5 ID:SGTC_2619|Compound:obliquin|FD-Score:8.14|P-value:1.29E-6 ID:SGTC_2671|Compound:danthron|FD-Score:7.61|P-value:5.54E-6 ID:SGTC_2679|Compound:rapamycin|FD-Score:8.78|P-value:1.95E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:7.05|P-value:2.32E-5 ID:SGTC_2759|Compound:disulfiram|FD-Score:6.76|P-value:4.70E-5 ID:SGTC_2766|Compound:oltipraz|FD-Score:11.00|P-value:1.14E-10 ID:SGTC_2799|Compound:7812892|FD-Score:8.53|P-value:4.18E-7 ID:SGTC_2912|Compound:7964298|FD-Score:23.70|P-value:9.53E-43 ID:SGTC_2928|Compound:9011484|FD-Score:5.52|P-value:7.06E-4 ID:SGTC_2930|Compound:9013230|FD-Score:8.07|P-value:1.55E-6 ID:SGTC_2962|Compound:9082311|FD-Score:7.05|P-value:2.29E-5 ID:SGTC_2971|Compound:9092186|FD-Score:6.87|P-value:3.55E-5 ID:SGTC_2974|Compound:9094440|FD-Score:7.00|P-value:2.62E-5 ID:SGTC_3037|Compound:9091026|FD-Score:9.16|P-value:6.06E-8 ID:SGTC_3068|Compound:9116768|FD-Score:-6.22|P-value:1.80E-4 ID:SGTC_3120|Compound:9124077|FD-Score:14.60|P-value:1.64E-17 ID:SGTC_3154|Compound:9100113|FD-Score:7.15|P-value:1.80E-5 ID:SGTC_3247|Compound:9135149|FD-Score:5.92|P-value:3.06E-4 ID:SGTC_3266|Compound:9136860|FD-Score:7.56|P-value:6.19E-6 ID:SGTC_3277|Compound:9138724|FD-Score:7.40|P-value:9.47E-6 ID:SGTC_3288|Compound:9119690|FD-Score:8.13|P-value:1.31E-6 ID:SGTC_3304|Compound:9125678|FD-Score:24.00|P-value:5.72E-44 ID:SGTC_3321|Compound:9137793|FD-Score:6.83|P-value:3.91E-5 ID:SGTC_22|Compound:0964-0034|FD-Score:5.59|P-value:6.10E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:8.41|P-value:5.94E-7 ID:SGTC_64|Compound:000l-0018|FD-Score:19.30|P-value:4.08E-29 ID:SGTC_67|Compound:0335-0847|FD-Score:5.44|P-value:8.28E-4 ID:SGTC_69|Compound:0096-0274|FD-Score:6.27|P-value:1.44E-4 ID:SGTC_93|Compound:0109-0045|FD-Score:6.17|P-value:1.80E-4 ID:SGTC_103|Compound:0844-0104|FD-Score:6.16|P-value:1.85E-4 ID:SGTC_138|Compound:0850-0259|FD-Score:8.23|P-value:9.91E-7 ID:SGTC_145|Compound:3737-0113|FD-Score:6.46|P-value:9.41E-5 ID:SGTC_157|Compound:1348-1695|FD-Score:12.80|P-value:9.29E-14 ID:SGTC_177|Compound:1327-0068|FD-Score:23.10|P-value:1.07E-40 ID:SGTC_181|Compound:1447-1644|FD-Score:6.58|P-value:7.09E-5 ID:SGTC_203|Compound:k066-0004|FD-Score:11.60|P-value:1.12E-11 ID:SGTC_227|Compound:fluconazole|FD-Score:8.25|P-value:9.38E-7 ID:SGTC_248|Compound:streptozotocin|FD-Score:8.15|P-value:1.25E-6 ID:SGTC_257|Compound:daunorubicin|FD-Score:14.20|P-value:1.10E-16 ID:SGTC_262|Compound:fenpropimorph|FD-Score:5.87|P-value:3.43E-4 ID:SGTC_267|Compound:4-Nitroquinoline-1-oxide  (4-NQO)|FD-Score:5.67|P-value:5.20E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:15.30|P-value:5.36E-19 ID:SGTC_272|Compound:doxorubicin|FD-Score:10.30|P-value:1.33E-9 ID:SGTC_273|Compound:hydroxyurea|FD-Score:7.61|P-value:5.45E-6 ID:SGTC_288|Compound:1315-0019|FD-Score:9.97|P-value:4.23E-9 ID:SGTC_319|Compound:1348-1596|FD-Score:7.29|P-value:1.24E-5 ID:SGTC_322|Compound:k048-0136|FD-Score:8.30|P-value:8.10E-7 ID:SGTC_324|Compound:1315-0088|FD-Score:10.20|P-value:1.89E-9 ID:SGTC_329|Compound:k048-0121|FD-Score:10.40|P-value:8.15E-10 ID:SGTC_331|Compound:k048-0133|FD-Score:8.74|P-value:2.26E-7 ID:SGTC_342|Compound:k048-0088|FD-Score:7.58|P-value:5.88E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:7.70|P-value:4.33E-6 ID:SGTC_354|Compound:2783-3500|FD-Score:7.19|P-value:1.61E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:16.60|P-value:6.06E-22 ID:SGTC_520|Compound:3584-0023|FD-Score:6.20|P-value:1.68E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:15.10|P-value:1.36E-18 ID:SGTC_557|Compound:1315-0110|FD-Score:5.89|P-value:3.31E-4 ID:SGTC_566|Compound:0958-0068|FD-Score:12.00|P-value:2.66E-12 ID:SGTC_576|Compound:1073-0113|FD-Score:6.59|P-value:7.00E-5 ID:SGTC_580|Compound:1123-0028|FD-Score:5.68|P-value:5.06E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:9.41|P-value:2.76E-8 ID:SGTC_590|Compound:k048-0076|FD-Score:6.52|P-value:8.19E-5 ID:SGTC_632|Compound:0781-2353|FD-Score:7.27|P-value:1.33E-5 ID:SGTC_642|Compound:0335-0876|FD-Score:6.58|P-value:7.18E-5 ID:SGTC_643|Compound:k048-0106|FD-Score:22.70|P-value:2.02E-39 ID:SGTC_651|Compound:3253-0966|FD-Score:-5.59|P-value:6.83E-4 ID:SGTC_666|Compound:0272-0154|FD-Score:7.83|P-value:3.03E-6 ID:SGTC_673|Compound:1082-0474|FD-Score:17.60|P-value:1.71E-24 ID:SGTC_709|Compound:3807-1509|FD-Score:18.20|P-value:4.85E-26 ID:SGTC_746|Compound:1095-0025|FD-Score:6.15|P-value:1.88E-4 ID:SGTC_783|Compound:0848-0141|FD-Score:18.10|P-value:6.98E-26 ID:SGTC_788|Compound:1182-0090|FD-Score:7.56|P-value:6.17E-6 ID:SGTC_794|Compound:k038-0031|FD-Score:5.35|P-value:9.74E-4 ID:SGTC_818|Compound:4072-2707|FD-Score:5.75|P-value:4.35E-4 ID:SGTC_825|Compound:1988-2224|FD-Score:12.60|P-value:1.86E-13 ID:SGTC_829|Compound:1635-0120|FD-Score:10.70|P-value:2.86E-10 ID:SGTC_839|Compound:0122-0028|FD-Score:5.88|P-value:3.33E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:13.40|P-value:5.67E-15 ID:SGTC_885|Compound:0865-0106|FD-Score:7.61|P-value:5.43E-6 ID:SGTC_916|Compound:4466-0038|FD-Score:10.80|P-value:2.23E-10 ID:SGTC_928|Compound:2764-0428|FD-Score:10.70|P-value:3.70E-10 ID:SGTC_951|Compound:1171-0579|FD-Score:7.94|P-value:2.22E-6 ID:SGTC_964|Compound:1287-0107|FD-Score:5.73|P-value:4.59E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:15.70|P-value:5.36E-20 ID:SGTC_984|Compound:1492-0255|FD-Score:5.94|P-value:2.93E-4 ID:SGTC_1026|Compound:k007-1105|FD-Score:6.27|P-value:1.45E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:7.80|P-value:3.27E-6 ID:SGTC_1090|Compound:efavirenz|FD-Score:6.95|P-value:2.92E-5 ID:SGTC_1098|Compound:clofazimine|FD-Score:9.06|P-value:8.45E-8 ID:SGTC_1133|Compound:3473-0247|FD-Score:18.20|P-value:4.34E-26 ID:SGTC_1168|Compound:k815-0004|FD-Score:6.20|P-value:1.68E-4 ID:SGTC_1171|Compound:0368-0077|FD-Score:6.48|P-value:8.88E-5 ID:SGTC_1229|Compound:0139-0193|FD-Score:6.13|P-value:1.98E-4 ID:SGTC_1239|Compound:0337-0584|FD-Score:11.20|P-value:5.38E-11 ID:SGTC_1269|Compound:0831-0796|FD-Score:-6.12|P-value:2.25E-4 ID:SGTC_1274|Compound:0865-0114|FD-Score:7.38|P-value:1.01E-5 ID:SGTC_1283|Compound:0922-0125|FD-Score:-5.79|P-value:4.57E-4 ID:SGTC_1311|Compound:1190-0148|FD-Score:7.71|P-value:4.21E-6 ID:SGTC_1371|Compound:2421-0008|FD-Score:7.62|P-value:5.28E-6 ID:SGTC_1374|Compound:2889-5571|FD-Score:15.10|P-value:1.37E-18 ID:SGTC_1396|Compound:3511-0007|FD-Score:7.72|P-value:4.03E-6 ID:SGTC_1446|Compound:4239-0190|FD-Score:8.32|P-value:7.74E-7 ID:SGTC_1453|Compound:4237-0541|FD-Score:6.52|P-value:8.18E-5 ID:SGTC_1493|Compound:4348-0038|FD-Score:8.54|P-value:4.10E-7 ID:SGTC_1522|Compound:st012842|FD-Score:-5.62|P-value:6.41E-4 ID:SGTC_1567|Compound:st069303|FD-Score:8.92|P-value:1.27E-7 ID:SGTC_1574|Compound:spiramycin|FD-Score:-5.79|P-value:4.53E-4 ID:SGTC_1584|Compound:6-fluoro-dl-tryptophan|FD-Score:5.55|P-value:6.54E-4 ID:SGTC_1651|Compound:st011928|FD-Score:7.21|P-value:1.54E-5 ID:SGTC_1652|Compound:st011932|FD-Score:23.70|P-value:9.92E-43 ID:SGTC_1672|Compound:st016598|FD-Score:5.37|P-value:9.49E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.10|P-value:8.30E-11 ID:SGTC_1696|Compound:st025591|FD-Score:5.36|P-value:9.53E-4 ID:SGTC_1707|Compound:st032323|FD-Score:8.57|P-value:3.67E-7 ID:SGTC_1722|Compound:st034304|FD-Score:16.00|P-value:1.22E-20 ID:SGTC_1723|Compound:st034307|FD-Score:10.10|P-value:2.50E-9 ID:SGTC_1731|Compound:st035964|FD-Score:9.21|P-value:5.18E-8 ID:SGTC_1773|Compound:st048542|FD-Score:5.98|P-value:2.73E-4 ID:SGTC_1800|Compound:st050079|FD-Score:5.74|P-value:4.45E-4 ID:SGTC_1831|Compound:st055328|FD-Score:7.18|P-value:1.66E-5 ID:SGTC_1844|Compound:rapamycin|FD-Score:9.65|P-value:1.28E-8 ID:SGTC_1868|Compound:st057644|FD-Score:5.67|P-value:5.19E-4 ID:SGTC_1870|Compound:st057514|FD-Score:10.30|P-value:1.35E-9 ID:SGTC_1875|Compound:nocodazole|FD-Score:8.88|P-value:1.47E-7 ID:SGTC_1884|Compound:5633444|FD-Score:11.70|P-value:8.19E-12 ID:SGTC_1898|Compound:st060199|FD-Score:5.50|P-value:7.28E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-5.58|P-value:7.01E-4 ID:SGTC_2041|Compound:5107442|FD-Score:8.09|P-value:1.50E-6 ID:SGTC_2056|Compound:5235370|FD-Score:-6.87|P-value:4.05E-5 ID:SGTC_2066|Compound:5222451|FD-Score:7.91|P-value:2.44E-6 ID:SGTC_2071|Compound:5230951|FD-Score:6.61|P-value:6.60E-5 ID:SGTC_2092|Compound:5303694|FD-Score:5.83|P-value:3.69E-4 ID:SGTC_2109|Compound:5483026|FD-Score:19.20|P-value:9.29E-29 ID:SGTC_2111|Compound:5486399|FD-Score:17.60|P-value:1.64E-24 ID:SGTC_2129|Compound:girgensonine|FD-Score:11.30|P-value:3.91E-11 ID:SGTC_2132|Compound:5317594|FD-Score:7.29|P-value:1.25E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:8.97|P-value:1.12E-7 ID:SGTC_2186|Compound:6124449|FD-Score:23.40|P-value:1.20E-41 ID:SGTC_2187|Compound:6125751|FD-Score:6.88|P-value:3.49E-5 ID:SGTC_2199|Compound:6590217|FD-Score:5.84|P-value:3.61E-4 ID:SGTC_2225|Compound:6654152|FD-Score:21.50|P-value:1.01E-35 ID:SGTC_2229|Compound:7354935|FD-Score:12.30|P-value:6.04E-13 ID:SGTC_2233|Compound:sulbentine|FD-Score:21.00|P-value:3.64E-34 ID:SGTC_2269|Compound:7935389|FD-Score:6.71|P-value:5.27E-5 ID:SGTC_2277|Compound:7947813|FD-Score:6.35|P-value:1.21E-4 ID:SGTC_2336|Compound:9001819|FD-Score:15.40|P-value:2.62E-19 ID:SGTC_2344|Compound:7990960|FD-Score:15.00|P-value:2.62E-18 ID:SGTC_2346|Compound:9031566|FD-Score:7.06|P-value:2.23E-5 ID:SGTC_2348|Compound:9022543|FD-Score:18.40|P-value:1.37E-26 ID:SGTC_2361|Compound:9034121|FD-Score:7.96|P-value:2.11E-6 ID:SGTC_2378|Compound:9074213|FD-Score:13.80|P-value:8.42E-16 ID:SGTC_2380|Compound:9035439|FD-Score:6.19|P-value:1.71E-4 ID:SGTC_2387|Compound:9077560|FD-Score:6.69|P-value:5.50E-5 ID:SGTC_2396|Compound:5342950|FD-Score:8.04|P-value:1.69E-6 ID:SGTC_2400|Compound:5203494|FD-Score:10.90|P-value:1.59E-10 ID:SGTC_2408|Compound:sulbentine|FD-Score:8.29|P-value:8.34E-7 ID:SGTC_2471|Compound:5466956|FD-Score:10.70|P-value:3.19E-10 ID:SGTC_2475|Compound:5812728|FD-Score:9.11|P-value:7.23E-8 ID:SGTC_2485|Compound:5633444|FD-Score:5.50|P-value:7.34E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:8.04|P-value:1.72E-6 ID:SGTC_2534|Compound:helenine|FD-Score:22.50|P-value:1.20E-38 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.36|P-value:9.56E-4 ID:SGTC_2575|Compound:plumbagin|FD-Score:7.26|P-value:1.35E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:7.92|P-value:2.38E-6 ID:SGTC_2617|Compound:dihydrotanshinone i|FD-Score:6.60|P-value:6.83E-5 ID:SGTC_2619|Compound:obliquin|FD-Score:8.14|P-value:1.29E-6 ID:SGTC_2671|Compound:danthron|FD-Score:7.61|P-value:5.54E-6 ID:SGTC_2679|Compound:rapamycin|FD-Score:8.78|P-value:1.95E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:7.05|P-value:2.32E-5 ID:SGTC_2759|Compound:disulfiram|FD-Score:6.76|P-value:4.70E-5 ID:SGTC_2766|Compound:oltipraz|FD-Score:11.00|P-value:1.14E-10 ID:SGTC_2799|Compound:7812892|FD-Score:8.53|P-value:4.18E-7 ID:SGTC_2912|Compound:7964298|FD-Score:23.70|P-value:9.53E-43 ID:SGTC_2928|Compound:9011484|FD-Score:5.52|P-value:7.06E-4 ID:SGTC_2930|Compound:9013230|FD-Score:8.07|P-value:1.55E-6 ID:SGTC_2962|Compound:9082311|FD-Score:7.05|P-value:2.29E-5 ID:SGTC_2971|Compound:9092186|FD-Score:6.87|P-value:3.55E-5 ID:SGTC_2974|Compound:9094440|FD-Score:7.00|P-value:2.62E-5 ID:SGTC_3037|Compound:9091026|FD-Score:9.16|P-value:6.06E-8 ID:SGTC_3068|Compound:9116768|FD-Score:-6.22|P-value:1.80E-4 ID:SGTC_3120|Compound:9124077|FD-Score:14.60|P-value:1.64E-17 ID:SGTC_3154|Compound:9100113|FD-Score:7.15|P-value:1.80E-5 ID:SGTC_3247|Compound:9135149|FD-Score:5.92|P-value:3.06E-4 ID:SGTC_3266|Compound:9136860|FD-Score:7.56|P-value:6.19E-6 ID:SGTC_3277|Compound:9138724|FD-Score:7.40|P-value:9.47E-6 ID:SGTC_3288|Compound:9119690|FD-Score:8.13|P-value:1.31E-6 ID:SGTC_3304|Compound:9125678|FD-Score:24.00|P-value:5.72E-44 ID:SGTC_3321|Compound:9137793|FD-Score:6.83|P-value:3.91E-5

Top fitness defect scores for YLR033W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_3304 9125678 24.00 46.1 µM 5.72E-44 5 5.24E-128 0.71
2 SGTC_2912 7964298 23.70 10.9 µM 9.53E-43 cell wall 1 2.44E-124 5.04
3 SGTC_1652 st011932 23.70 78.0 µM 9.92E-43 RSC complex & mRNA processing 1 2.75E-124 2.89
4 SGTC_2186 6124449 23.40 200.0 µM 1.20E-41 RSC complex & mRNA processing 1 4.94E-121 8.19
5 SGTC_177 1327-0068 23.10 8.4 µM 1.07E-40 2 3.46E-118 8.14
6 SGTC_643 k048-0106 22.70 28.4 µM 2.02E-39 RSC & ERG11 1 2.35E-114 3.98
7 SGTC_2534 helenine 22.50 20.1 µM 1.20E-38 RSC complex & mRNA processing 1 5.00E-112 9.56
8 SGTC_2225 6654152 21.50 15.4 µM 1.01E-35 2 2.99E-103 7.74
9 SGTC_2233 sulbentine 21.00 40.4 µM 3.64E-34 2 1.39E-98 6.19
10 SGTC_64 000l-0018 19.30 272.1 µM 4.08E-29 ubiquinone biosynthesis & proteasome 4 1.91E-83 2.27
11 SGTC_2109 5483026 19.20 200.0 µM 9.29E-29 RSC complex & mRNA processing 2 2.25E-82 4.78
12 SGTC_2348 9022543 18.40 33.4 µM 1.37E-26 mitochondrial processes 2 7.11E-76 3.65
13 SGTC_1133 3473-0247 18.20 50.0 µM 4.34E-26 RSC complex & mRNA processing 1 2.23E-74 3.77
14 SGTC_709 3807-1509 18.20 243.0 µM 4.85E-26 RSC complex & mRNA processing 1 3.10E-74 5.38
15 SGTC_783 0848-0141 18.10 92.7 µM 6.98E-26 RSC & ERG11 1 9.25E-74 9.02
16 SGTC_2111 5486399 17.60 200.0 µM 1.64E-24 2 1.17E-69 4.12
17 SGTC_673 1082-0474 17.60 110.0 µM 1.71E-24 RSC complex & mRNA processing 1 1.34E-69 1.83
18 SGTC_445 e6 berbamine 16.60 66.0 µM 6.06E-22 NEO1-PIK1 3 5.64E-62 4.18
19 SGTC_1722 st034304 16.00 3.6 µM 1.22E-20 mitochondrial processes 1 4.51E-58 10.10
20 SGTC_970 1315-0089 15.70 19.5 µM 5.36E-20 RSC & ERG11 1 3.71E-56 7.36

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.707 0 YFR037C RSC8 het Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
0.677 0 YML127W RSC9 het Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
0.568 7.71E-286 YPR034W ARP7 het Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation
0.564 3.66E-280 YIL126W STH1 het ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p
0.542 4.05E-255 YMR033W ARP9 het Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation
0.520 7.47E-232 YLR321C SFH1 het Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog
0.486 4.08E-198 YNR016C ACC1 het Acetyl-CoA carboxylase, biotin containing enzyme; catalyzes the carboxylation of cytosolic acetyl-CoA to form malonyl-CoA and regulates histone acetylation by regulating the availablity of acetyl-CoA; required for de novo biosynthesis of long-chain fatty acids;
0.421 2.19E-143 YJL081C ARP4 het Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
0.405 3.26E-132 YER165W PAB1 het Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
0.386 1.46E-119 YGL093W SPC105 het Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components
0.360 2.52E-103 YBR091C TIM12 het Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
0.352 1.95E-98 YAL001C TFC3 het Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding
0.340 1.73E-91 YPR107C YTH1 het Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation
0.330 9.94E-86 YJL039C NUP192 het Essential subunit of the inner ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport; homologous to human NUP205
0.329 2.35E-85 YOR236W DFR1 het Dihydrofolate reductase involved in tetrahydrofolate biosynthesis; required for respiratory metabolism