YLR208W / SEC13

Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress

Zygosity: Heterozygous strain
fixedexpanded
Profile for YLR208W / SEC13

Click on Significant Values for Screen Details ID:SGTC_17|Compound:0960-0276|FD-Score:5.17|P-value:1.72E-4 ID:SGTC_23|Compound:0213-0011|FD-Score:5.07|P-value:2.23E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:14.00|P-value:1.83E-22 ID:SGTC_43|Compound:0570-0105|FD-Score:6.72|P-value:1.65E-6 ID:SGTC_57|Compound:miconazole|FD-Score:5.81|P-value:2.86E-5 ID:SGTC_89|Compound:0302-0250|FD-Score:14.20|P-value:2.87E-23 ID:SGTC_117|Compound:lucigenin|FD-Score:5.91|P-value:2.17E-5 ID:SGTC_126|Compound:0417-1624|FD-Score:8.25|P-value:5.43E-9 ID:SGTC_133|Compound:0724-0033|FD-Score:6.87|P-value:9.77E-7 ID:SGTC_138|Compound:0850-0259|FD-Score:17.30|P-value:2.68E-33 ID:SGTC_161|Compound:4065-0411|FD-Score:12.40|P-value:4.73E-18 ID:SGTC_226|Compound:1,3-diallylurea|FD-Score:4.79|P-value:4.62E-4 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:5.96|P-value:1.82E-5 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:6.12|P-value:1.13E-5 ID:SGTC_269|Compound:exalamide|FD-Score:8.60|P-value:1.31E-9 ID:SGTC_287|Compound:k060-0039|FD-Score:5.63|P-value:4.78E-5 ID:SGTC_290|Compound:2043-6722|FD-Score:22.20|P-value:7.71E-54 ID:SGTC_307|Compound:1501-1223|FD-Score:4.49|P-value:9.40E-4 ID:SGTC_349|Compound:k015-0014|FD-Score:6.38|P-value:5.03E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:4.64|P-value:6.53E-4 ID:SGTC_354|Compound:2783-3500|FD-Score:6.02|P-value:1.55E-5 ID:SGTC_362|Compound:0310-0100|FD-Score:7.71|P-value:4.70E-8 ID:SGTC_371|Compound:0195-0006|FD-Score:5.26|P-value:1.37E-4 ID:SGTC_375|Compound:3970-0961|FD-Score:4.68|P-value:5.96E-4 ID:SGTC_389|Compound:tpck|FD-Score:4.90|P-value:3.50E-4 ID:SGTC_408|Compound:cantharidin|FD-Score:6.43|P-value:4.24E-6 ID:SGTC_422|Compound:cantharidin|FD-Score:4.68|P-value:6.01E-4 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:6.34|P-value:5.68E-6 ID:SGTC_483|Compound:fpl-64176|FD-Score:6.06|P-value:1.37E-5 ID:SGTC_519|Compound:k048-0011|FD-Score:5.35|P-value:1.06E-4 ID:SGTC_542|Compound:3381-0244|FD-Score:9.92|P-value:3.13E-12 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:8.44|P-value:2.52E-9 ID:SGTC_551|Compound:k048-0028|FD-Score:4.90|P-value:3.44E-4 ID:SGTC_557|Compound:1315-0110|FD-Score:4.92|P-value:3.32E-4 ID:SGTC_592|Compound:k241-0073|FD-Score:12.40|P-value:3.52E-18 ID:SGTC_595|Compound:3909-8003|FD-Score:6.96|P-value:7.22E-7 ID:SGTC_619|Compound:1652-1634|FD-Score:10.30|P-value:5.23E-13 ID:SGTC_621|Compound:3584-0052|FD-Score:5.65|P-value:4.62E-5 ID:SGTC_638|Compound:3970-0837|FD-Score:11.50|P-value:7.38E-16 ID:SGTC_666|Compound:0272-0154|FD-Score:6.05|P-value:1.38E-5 ID:SGTC_682|Compound:0kpi-0099|FD-Score:9.18|P-value:1.00E-10 ID:SGTC_689|Compound:0833-0039|FD-Score:4.56|P-value:7.98E-4 ID:SGTC_690|Compound:glyoxal|FD-Score:4.99|P-value:2.75E-4 ID:SGTC_723|Compound:4182-0001|FD-Score:19.60|P-value:2.72E-42 ID:SGTC_727|Compound:3032-0951|FD-Score:4.76|P-value:4.92E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:4.47|P-value:9.76E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:11.10|P-value:6.50E-15 ID:SGTC_784|Compound:4579-0127|FD-Score:9.43|P-value:3.24E-11 ID:SGTC_786|Compound:4544-0069|FD-Score:30.40|P-value:1.30E-98 ID:SGTC_790|Compound:1575-0012|FD-Score:14.10|P-value:5.98E-23 ID:SGTC_801|Compound:0866-0028|FD-Score:4.65|P-value:6.38E-4 ID:SGTC_806|Compound:3966-4455|FD-Score:4.66|P-value:6.23E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:6.62|P-value:2.28E-6 ID:SGTC_828|Compound:2074-0507|FD-Score:4.80|P-value:4.51E-4 ID:SGTC_848|Compound:0368-0089|FD-Score:6.10|P-value:1.21E-5 ID:SGTC_855|Compound:0428-0020|FD-Score:7.21|P-value:2.97E-7 ID:SGTC_867|Compound:0518-0118|FD-Score:5.86|P-value:2.49E-5 ID:SGTC_872|Compound:0588-0139|FD-Score:6.13|P-value:1.10E-5 ID:SGTC_874|Compound:0599-0792|FD-Score:7.84|P-value:2.77E-8 ID:SGTC_878|Compound:0828-0289|FD-Score:19.80|P-value:3.19E-43 ID:SGTC_890|Compound:0929-0006|FD-Score:6.42|P-value:4.43E-6 ID:SGTC_964|Compound:1287-0107|FD-Score:4.98|P-value:2.82E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.02|P-value:2.53E-4 ID:SGTC_993|Compound:3909-8757|FD-Score:19.80|P-value:4.42E-43 ID:SGTC_996|Compound:3970-0799|FD-Score:5.16|P-value:1.78E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:13.10|P-value:6.73E-20 ID:SGTC_1022|Compound:4477-0945|FD-Score:5.51|P-value:6.85E-5 ID:SGTC_1026|Compound:k007-1105|FD-Score:16.80|P-value:1.56E-31 ID:SGTC_1034|Compound:k072-0165|FD-Score:4.73|P-value:5.34E-4 ID:SGTC_1036|Compound:k216-0215|FD-Score:-5.01|P-value:2.51E-4 ID:SGTC_1041|Compound:0206-0046|FD-Score:7.05|P-value:5.28E-7 ID:SGTC_1053|Compound:3366-3204|FD-Score:6.71|P-value:1.70E-6 ID:SGTC_1058|Compound:3448-5425|FD-Score:5.72|P-value:3.71E-5 ID:SGTC_1060|Compound:3448-7350|FD-Score:11.60|P-value:6.11E-16 ID:SGTC_1061|Compound:3448-9325|FD-Score:6.74|P-value:1.54E-6 ID:SGTC_1068|Compound:loratadine|FD-Score:4.58|P-value:7.68E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.44|P-value:3.14E-11 ID:SGTC_1104|Compound:tacrolimus|FD-Score:8.07|P-value:1.16E-8 ID:SGTC_1168|Compound:k815-0004|FD-Score:15.50|P-value:3.52E-27 ID:SGTC_1237|Compound:0330-0133|FD-Score:8.82|P-value:5.04E-10 ID:SGTC_1239|Compound:0337-0584|FD-Score:7.12|P-value:4.09E-7 ID:SGTC_1255|Compound:0566-0045|FD-Score:-4.53|P-value:8.36E-4 ID:SGTC_1266|Compound:0828-0227|FD-Score:4.66|P-value:6.31E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:7.73|P-value:4.33E-8 ID:SGTC_1268|Compound:0828-0275|FD-Score:9.38|P-value:4.04E-11 ID:SGTC_1320|Compound:1313-0481|FD-Score:12.40|P-value:4.81E-18 ID:SGTC_1335|Compound:1486-0900|FD-Score:5.02|P-value:2.58E-4 ID:SGTC_1399|Compound:3562-5772|FD-Score:8.99|P-value:2.35E-10 ID:SGTC_1400|Compound:3771-8998|FD-Score:4.67|P-value:6.14E-4 ID:SGTC_1416|Compound:3966-0321|FD-Score:25.50|P-value:2.05E-70 ID:SGTC_1418|Compound:3966-3099|FD-Score:6.67|P-value:1.93E-6 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:25.70|P-value:4.00E-71 ID:SGTC_1424|Compound:4048-1941|FD-Score:5.32|P-value:1.14E-4 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.64|P-value:6.52E-4 ID:SGTC_1460|Compound:k062-0059|FD-Score:4.53|P-value:8.52E-4 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:7.26|P-value:2.48E-7 ID:SGTC_1547|Compound:harmine|FD-Score:8.98|P-value:2.53E-10 ID:SGTC_1561|Compound:5-methoxyflavone|FD-Score:4.55|P-value:8.20E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:6.96|P-value:7.12E-7 ID:SGTC_1600|Compound:coumarin 106|FD-Score:8.22|P-value:6.32E-9 ID:SGTC_1654|Compound:st012436|FD-Score:4.58|P-value:7.61E-4 ID:SGTC_1655|Compound:st012546|FD-Score:20.40|P-value:1.03E-45 ID:SGTC_1724|Compound:st037281|FD-Score:6.46|P-value:3.81E-6 ID:SGTC_1743|Compound:st037606|FD-Score:43.60|P-value:3.97E-201 ID:SGTC_1751|Compound:st044839|FD-Score:5.18|P-value:1.67E-4 ID:SGTC_1764|Compound:st044502|FD-Score:7.21|P-value:2.94E-7 ID:SGTC_1770|Compound:st043884|FD-Score:4.87|P-value:3.72E-4 ID:SGTC_1772|Compound:st048439|FD-Score:13.90|P-value:3.87E-22 ID:SGTC_1837|Compound:st055472|FD-Score:5.76|P-value:3.37E-5 ID:SGTC_1870|Compound:st057514|FD-Score:7.60|P-value:7.19E-8 ID:SGTC_1881|Compound:5652484|FD-Score:5.21|P-value:1.53E-4 ID:SGTC_1907|Compound:st060210|FD-Score:6.10|P-value:1.20E-5 ID:SGTC_1909|Compound:st060837|FD-Score:9.17|P-value:1.05E-10 ID:SGTC_1933|Compound:st074711|FD-Score:5.23|P-value:1.47E-4 ID:SGTC_1936|Compound:st074407|FD-Score:7.40|P-value:1.51E-7 ID:SGTC_1965|Compound:Pectolinarigenin|FD-Score:7.37|P-value:1.66E-7 ID:SGTC_1975|Compound:st070967|FD-Score:10.90|P-value:2.09E-14 ID:SGTC_1982|Compound:st072467|FD-Score:4.65|P-value:6.37E-4 ID:SGTC_1994|Compound:st072947|FD-Score:5.81|P-value:2.90E-5 ID:SGTC_2013|Compound:4024628|FD-Score:4.90|P-value:3.49E-4 ID:SGTC_2025|Compound:5147754|FD-Score:35.10|P-value:1.20E-130 ID:SGTC_2063|Compound:5246145|FD-Score:6.18|P-value:9.26E-6 ID:SGTC_2106|Compound:5357045|FD-Score:4.93|P-value:3.20E-4 ID:SGTC_2130|Compound:NSC 7|FD-Score:5.41|P-value:9.01E-5 ID:SGTC_2136|Compound:5328288|FD-Score:6.54|P-value:3.00E-6 ID:SGTC_2137|Compound:5261020|FD-Score:6.04|P-value:1.45E-5 ID:SGTC_2187|Compound:6125751|FD-Score:6.21|P-value:8.48E-6 ID:SGTC_2201|Compound:6605497|FD-Score:9.27|P-value:6.68E-11 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.51|P-value:6.89E-5 ID:SGTC_2277|Compound:7947813|FD-Score:5.03|P-value:2.49E-4 ID:SGTC_2296|Compound:7971656|FD-Score:6.70|P-value:1.77E-6 ID:SGTC_2310|Compound:7668677|FD-Score:-4.49|P-value:9.21E-4 ID:SGTC_2315|Compound:7733312|FD-Score:7.34|P-value:1.87E-7 ID:SGTC_2316|Compound:5844804|FD-Score:5.45|P-value:8.10E-5 ID:SGTC_2339|Compound:9000433|FD-Score:-4.67|P-value:5.93E-4 ID:SGTC_2361|Compound:9034121|FD-Score:5.27|P-value:1.32E-4 ID:SGTC_2417|Compound:cerulenin|FD-Score:6.07|P-value:1.32E-5 ID:SGTC_2444|Compound:5485484|FD-Score:5.56|P-value:5.99E-5 ID:SGTC_2447|Compound:5741742|FD-Score:6.62|P-value:2.26E-6 ID:SGTC_2472|Compound:5377652|FD-Score:7.79|P-value:3.38E-8 ID:SGTC_2476|Compound:5806916|FD-Score:5.72|P-value:3.71E-5 ID:SGTC_2478|Compound:5763493|FD-Score:11.50|P-value:8.79E-16 ID:SGTC_2488|Compound:5268135|FD-Score:15.50|P-value:3.43E-27 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:10.40|P-value:2.68E-13 ID:SGTC_2574|Compound:2',4'-dihydroxychalcone|FD-Score:5.86|P-value:2.51E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.10|P-value:6.14E-20 ID:SGTC_2585|Compound:alliin|FD-Score:6.46|P-value:3.81E-6 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.98|P-value:2.83E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:7.32|P-value:1.96E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:17.90|P-value:1.51E-35 ID:SGTC_2778|Compound:tioconazole|FD-Score:5.21|P-value:1.53E-4 ID:SGTC_2781|Compound:5567276|FD-Score:4.73|P-value:5.26E-4 ID:SGTC_2805|Compound:7950783|FD-Score:5.17|P-value:1.73E-4 ID:SGTC_2809|Compound:7964133|FD-Score:4.92|P-value:3.34E-4 ID:SGTC_2810|Compound:7959871|FD-Score:6.03|P-value:1.48E-5 ID:SGTC_2845|Compound:9003024|FD-Score:9.43|P-value:3.19E-11 ID:SGTC_2851|Compound:9015922|FD-Score:4.48|P-value:9.71E-4 ID:SGTC_2890|Compound:9046729|FD-Score:6.93|P-value:7.90E-7 ID:SGTC_2912|Compound:7964298|FD-Score:14.10|P-value:6.58E-23 ID:SGTC_2967|Compound:9089538|FD-Score:4.68|P-value:6.04E-4 ID:SGTC_2990|Compound:9074105|FD-Score:-6.21|P-value:8.25E-6 ID:SGTC_2993|Compound:9054257|FD-Score:-4.97|P-value:2.83E-4 ID:SGTC_2996|Compound:9066192|FD-Score:-9.15|P-value:1.10E-10 ID:SGTC_3018|Compound:9082602|FD-Score:4.52|P-value:8.81E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:5.21|P-value:1.57E-4 ID:SGTC_3063|Compound:1327-0034|FD-Score:5.84|P-value:2.61E-5 ID:SGTC_3119|Compound:9125183|FD-Score:5.38|P-value:9.86E-5 ID:SGTC_3155|Compound:9099265|FD-Score:5.47|P-value:7.70E-5 ID:SGTC_3197|Compound:9113331|FD-Score:21.20|P-value:3.41E-49 ID:SGTC_3200|Compound:9114385|FD-Score:43.30|P-value:1.01E-197 ID:SGTC_3237|Compound:9133362|FD-Score:4.99|P-value:2.78E-4 ID:SGTC_3307|Compound:9126885|FD-Score:7.19|P-value:3.19E-7 ID:SGTC_17|Compound:0960-0276|FD-Score:5.17|P-value:1.72E-4 ID:SGTC_23|Compound:0213-0011|FD-Score:5.07|P-value:2.23E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:14.00|P-value:1.83E-22 ID:SGTC_43|Compound:0570-0105|FD-Score:6.72|P-value:1.65E-6 ID:SGTC_57|Compound:miconazole|FD-Score:5.81|P-value:2.86E-5 ID:SGTC_89|Compound:0302-0250|FD-Score:14.20|P-value:2.87E-23 ID:SGTC_117|Compound:lucigenin|FD-Score:5.91|P-value:2.17E-5 ID:SGTC_126|Compound:0417-1624|FD-Score:8.25|P-value:5.43E-9 ID:SGTC_133|Compound:0724-0033|FD-Score:6.87|P-value:9.77E-7 ID:SGTC_138|Compound:0850-0259|FD-Score:17.30|P-value:2.68E-33 ID:SGTC_161|Compound:4065-0411|FD-Score:12.40|P-value:4.73E-18 ID:SGTC_226|Compound:1,3-diallylurea|FD-Score:4.79|P-value:4.62E-4 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:5.96|P-value:1.82E-5 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:6.12|P-value:1.13E-5 ID:SGTC_269|Compound:exalamide|FD-Score:8.60|P-value:1.31E-9 ID:SGTC_287|Compound:k060-0039|FD-Score:5.63|P-value:4.78E-5 ID:SGTC_290|Compound:2043-6722|FD-Score:22.20|P-value:7.71E-54 ID:SGTC_307|Compound:1501-1223|FD-Score:4.49|P-value:9.40E-4 ID:SGTC_349|Compound:k015-0014|FD-Score:6.38|P-value:5.03E-6 ID:SGTC_351|Compound:caspofungin|FD-Score:4.64|P-value:6.53E-4 ID:SGTC_354|Compound:2783-3500|FD-Score:6.02|P-value:1.55E-5 ID:SGTC_362|Compound:0310-0100|FD-Score:7.71|P-value:4.70E-8 ID:SGTC_371|Compound:0195-0006|FD-Score:5.26|P-value:1.37E-4 ID:SGTC_375|Compound:3970-0961|FD-Score:4.68|P-value:5.96E-4 ID:SGTC_389|Compound:tpck|FD-Score:4.90|P-value:3.50E-4 ID:SGTC_408|Compound:cantharidin|FD-Score:6.43|P-value:4.24E-6 ID:SGTC_422|Compound:cantharidin|FD-Score:4.68|P-value:6.01E-4 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:6.34|P-value:5.68E-6 ID:SGTC_483|Compound:fpl-64176|FD-Score:6.06|P-value:1.37E-5 ID:SGTC_519|Compound:k048-0011|FD-Score:5.35|P-value:1.06E-4 ID:SGTC_542|Compound:3381-0244|FD-Score:9.92|P-value:3.13E-12 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:8.44|P-value:2.52E-9 ID:SGTC_551|Compound:k048-0028|FD-Score:4.90|P-value:3.44E-4 ID:SGTC_557|Compound:1315-0110|FD-Score:4.92|P-value:3.32E-4 ID:SGTC_592|Compound:k241-0073|FD-Score:12.40|P-value:3.52E-18 ID:SGTC_595|Compound:3909-8003|FD-Score:6.96|P-value:7.22E-7 ID:SGTC_619|Compound:1652-1634|FD-Score:10.30|P-value:5.23E-13 ID:SGTC_621|Compound:3584-0052|FD-Score:5.65|P-value:4.62E-5 ID:SGTC_638|Compound:3970-0837|FD-Score:11.50|P-value:7.38E-16 ID:SGTC_666|Compound:0272-0154|FD-Score:6.05|P-value:1.38E-5 ID:SGTC_682|Compound:0kpi-0099|FD-Score:9.18|P-value:1.00E-10 ID:SGTC_689|Compound:0833-0039|FD-Score:4.56|P-value:7.98E-4 ID:SGTC_690|Compound:glyoxal|FD-Score:4.99|P-value:2.75E-4 ID:SGTC_723|Compound:4182-0001|FD-Score:19.60|P-value:2.72E-42 ID:SGTC_727|Compound:3032-0951|FD-Score:4.76|P-value:4.92E-4 ID:SGTC_733|Compound:4069-0007|FD-Score:4.47|P-value:9.76E-4 ID:SGTC_764|Compound:1951-2361|FD-Score:11.10|P-value:6.50E-15 ID:SGTC_784|Compound:4579-0127|FD-Score:9.43|P-value:3.24E-11 ID:SGTC_786|Compound:4544-0069|FD-Score:30.40|P-value:1.30E-98 ID:SGTC_790|Compound:1575-0012|FD-Score:14.10|P-value:5.98E-23 ID:SGTC_801|Compound:0866-0028|FD-Score:4.65|P-value:6.38E-4 ID:SGTC_806|Compound:3966-4455|FD-Score:4.66|P-value:6.23E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:6.62|P-value:2.28E-6 ID:SGTC_828|Compound:2074-0507|FD-Score:4.80|P-value:4.51E-4 ID:SGTC_848|Compound:0368-0089|FD-Score:6.10|P-value:1.21E-5 ID:SGTC_855|Compound:0428-0020|FD-Score:7.21|P-value:2.97E-7 ID:SGTC_867|Compound:0518-0118|FD-Score:5.86|P-value:2.49E-5 ID:SGTC_872|Compound:0588-0139|FD-Score:6.13|P-value:1.10E-5 ID:SGTC_874|Compound:0599-0792|FD-Score:7.84|P-value:2.77E-8 ID:SGTC_878|Compound:0828-0289|FD-Score:19.80|P-value:3.19E-43 ID:SGTC_890|Compound:0929-0006|FD-Score:6.42|P-value:4.43E-6 ID:SGTC_964|Compound:1287-0107|FD-Score:4.98|P-value:2.82E-4 ID:SGTC_970|Compound:1315-0089|FD-Score:5.02|P-value:2.53E-4 ID:SGTC_993|Compound:3909-8757|FD-Score:19.80|P-value:4.42E-43 ID:SGTC_996|Compound:3970-0799|FD-Score:5.16|P-value:1.78E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:13.10|P-value:6.73E-20 ID:SGTC_1022|Compound:4477-0945|FD-Score:5.51|P-value:6.85E-5 ID:SGTC_1026|Compound:k007-1105|FD-Score:16.80|P-value:1.56E-31 ID:SGTC_1034|Compound:k072-0165|FD-Score:4.73|P-value:5.34E-4 ID:SGTC_1036|Compound:k216-0215|FD-Score:-5.01|P-value:2.51E-4 ID:SGTC_1041|Compound:0206-0046|FD-Score:7.05|P-value:5.28E-7 ID:SGTC_1053|Compound:3366-3204|FD-Score:6.71|P-value:1.70E-6 ID:SGTC_1058|Compound:3448-5425|FD-Score:5.72|P-value:3.71E-5 ID:SGTC_1060|Compound:3448-7350|FD-Score:11.60|P-value:6.11E-16 ID:SGTC_1061|Compound:3448-9325|FD-Score:6.74|P-value:1.54E-6 ID:SGTC_1068|Compound:loratadine|FD-Score:4.58|P-value:7.68E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:9.44|P-value:3.14E-11 ID:SGTC_1104|Compound:tacrolimus|FD-Score:8.07|P-value:1.16E-8 ID:SGTC_1168|Compound:k815-0004|FD-Score:15.50|P-value:3.52E-27 ID:SGTC_1237|Compound:0330-0133|FD-Score:8.82|P-value:5.04E-10 ID:SGTC_1239|Compound:0337-0584|FD-Score:7.12|P-value:4.09E-7 ID:SGTC_1255|Compound:0566-0045|FD-Score:-4.53|P-value:8.36E-4 ID:SGTC_1266|Compound:0828-0227|FD-Score:4.66|P-value:6.31E-4 ID:SGTC_1267|Compound:0828-0272|FD-Score:7.73|P-value:4.33E-8 ID:SGTC_1268|Compound:0828-0275|FD-Score:9.38|P-value:4.04E-11 ID:SGTC_1320|Compound:1313-0481|FD-Score:12.40|P-value:4.81E-18 ID:SGTC_1335|Compound:1486-0900|FD-Score:5.02|P-value:2.58E-4 ID:SGTC_1399|Compound:3562-5772|FD-Score:8.99|P-value:2.35E-10 ID:SGTC_1400|Compound:3771-8998|FD-Score:4.67|P-value:6.14E-4 ID:SGTC_1416|Compound:3966-0321|FD-Score:25.50|P-value:2.05E-70 ID:SGTC_1418|Compound:3966-3099|FD-Score:6.67|P-value:1.93E-6 ID:SGTC_1420|Compound:4'-methoxyflavone|FD-Score:25.70|P-value:4.00E-71 ID:SGTC_1424|Compound:4048-1941|FD-Score:5.32|P-value:1.14E-4 ID:SGTC_1450|Compound:4112-4260|FD-Score:4.64|P-value:6.52E-4 ID:SGTC_1460|Compound:k062-0059|FD-Score:4.53|P-value:8.52E-4 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:7.26|P-value:2.48E-7 ID:SGTC_1547|Compound:harmine|FD-Score:8.98|P-value:2.53E-10 ID:SGTC_1561|Compound:5-methoxyflavone|FD-Score:4.55|P-value:8.20E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:6.96|P-value:7.12E-7 ID:SGTC_1600|Compound:coumarin 106|FD-Score:8.22|P-value:6.32E-9 ID:SGTC_1654|Compound:st012436|FD-Score:4.58|P-value:7.61E-4 ID:SGTC_1655|Compound:st012546|FD-Score:20.40|P-value:1.03E-45 ID:SGTC_1724|Compound:st037281|FD-Score:6.46|P-value:3.81E-6 ID:SGTC_1743|Compound:st037606|FD-Score:43.60|P-value:3.97E-201 ID:SGTC_1751|Compound:st044839|FD-Score:5.18|P-value:1.67E-4 ID:SGTC_1764|Compound:st044502|FD-Score:7.21|P-value:2.94E-7 ID:SGTC_1770|Compound:st043884|FD-Score:4.87|P-value:3.72E-4 ID:SGTC_1772|Compound:st048439|FD-Score:13.90|P-value:3.87E-22 ID:SGTC_1837|Compound:st055472|FD-Score:5.76|P-value:3.37E-5 ID:SGTC_1870|Compound:st057514|FD-Score:7.60|P-value:7.19E-8 ID:SGTC_1881|Compound:5652484|FD-Score:5.21|P-value:1.53E-4 ID:SGTC_1907|Compound:st060210|FD-Score:6.10|P-value:1.20E-5 ID:SGTC_1909|Compound:st060837|FD-Score:9.17|P-value:1.05E-10 ID:SGTC_1933|Compound:st074711|FD-Score:5.23|P-value:1.47E-4 ID:SGTC_1936|Compound:st074407|FD-Score:7.40|P-value:1.51E-7 ID:SGTC_1965|Compound:Pectolinarigenin|FD-Score:7.37|P-value:1.66E-7 ID:SGTC_1975|Compound:st070967|FD-Score:10.90|P-value:2.09E-14 ID:SGTC_1982|Compound:st072467|FD-Score:4.65|P-value:6.37E-4 ID:SGTC_1994|Compound:st072947|FD-Score:5.81|P-value:2.90E-5 ID:SGTC_2013|Compound:4024628|FD-Score:4.90|P-value:3.49E-4 ID:SGTC_2025|Compound:5147754|FD-Score:35.10|P-value:1.20E-130 ID:SGTC_2063|Compound:5246145|FD-Score:6.18|P-value:9.26E-6 ID:SGTC_2106|Compound:5357045|FD-Score:4.93|P-value:3.20E-4 ID:SGTC_2130|Compound:NSC 7|FD-Score:5.41|P-value:9.01E-5 ID:SGTC_2136|Compound:5328288|FD-Score:6.54|P-value:3.00E-6 ID:SGTC_2137|Compound:5261020|FD-Score:6.04|P-value:1.45E-5 ID:SGTC_2187|Compound:6125751|FD-Score:6.21|P-value:8.48E-6 ID:SGTC_2201|Compound:6605497|FD-Score:9.27|P-value:6.68E-11 ID:SGTC_2249|Compound:haloperidol|FD-Score:5.51|P-value:6.89E-5 ID:SGTC_2277|Compound:7947813|FD-Score:5.03|P-value:2.49E-4 ID:SGTC_2296|Compound:7971656|FD-Score:6.70|P-value:1.77E-6 ID:SGTC_2310|Compound:7668677|FD-Score:-4.49|P-value:9.21E-4 ID:SGTC_2315|Compound:7733312|FD-Score:7.34|P-value:1.87E-7 ID:SGTC_2316|Compound:5844804|FD-Score:5.45|P-value:8.10E-5 ID:SGTC_2339|Compound:9000433|FD-Score:-4.67|P-value:5.93E-4 ID:SGTC_2361|Compound:9034121|FD-Score:5.27|P-value:1.32E-4 ID:SGTC_2417|Compound:cerulenin|FD-Score:6.07|P-value:1.32E-5 ID:SGTC_2444|Compound:5485484|FD-Score:5.56|P-value:5.99E-5 ID:SGTC_2447|Compound:5741742|FD-Score:6.62|P-value:2.26E-6 ID:SGTC_2472|Compound:5377652|FD-Score:7.79|P-value:3.38E-8 ID:SGTC_2476|Compound:5806916|FD-Score:5.72|P-value:3.71E-5 ID:SGTC_2478|Compound:5763493|FD-Score:11.50|P-value:8.79E-16 ID:SGTC_2488|Compound:5268135|FD-Score:15.50|P-value:3.43E-27 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:10.40|P-value:2.68E-13 ID:SGTC_2574|Compound:2',4'-dihydroxychalcone|FD-Score:5.86|P-value:2.51E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.10|P-value:6.14E-20 ID:SGTC_2585|Compound:alliin|FD-Score:6.46|P-value:3.81E-6 ID:SGTC_2613|Compound:3',4'-dimethoxydalbergione|FD-Score:4.98|P-value:2.83E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:7.32|P-value:1.96E-7 ID:SGTC_2756|Compound:carbadox|FD-Score:17.90|P-value:1.51E-35 ID:SGTC_2778|Compound:tioconazole|FD-Score:5.21|P-value:1.53E-4 ID:SGTC_2781|Compound:5567276|FD-Score:4.73|P-value:5.26E-4 ID:SGTC_2805|Compound:7950783|FD-Score:5.17|P-value:1.73E-4 ID:SGTC_2809|Compound:7964133|FD-Score:4.92|P-value:3.34E-4 ID:SGTC_2810|Compound:7959871|FD-Score:6.03|P-value:1.48E-5 ID:SGTC_2845|Compound:9003024|FD-Score:9.43|P-value:3.19E-11 ID:SGTC_2851|Compound:9015922|FD-Score:4.48|P-value:9.71E-4 ID:SGTC_2890|Compound:9046729|FD-Score:6.93|P-value:7.90E-7 ID:SGTC_2912|Compound:7964298|FD-Score:14.10|P-value:6.58E-23 ID:SGTC_2967|Compound:9089538|FD-Score:4.68|P-value:6.04E-4 ID:SGTC_2990|Compound:9074105|FD-Score:-6.21|P-value:8.25E-6 ID:SGTC_2993|Compound:9054257|FD-Score:-4.97|P-value:2.83E-4 ID:SGTC_2996|Compound:9066192|FD-Score:-9.15|P-value:1.10E-10 ID:SGTC_3018|Compound:9082602|FD-Score:4.52|P-value:8.81E-4 ID:SGTC_3059|Compound:1327-0034|FD-Score:5.21|P-value:1.57E-4 ID:SGTC_3063|Compound:1327-0034|FD-Score:5.84|P-value:2.61E-5 ID:SGTC_3119|Compound:9125183|FD-Score:5.38|P-value:9.86E-5 ID:SGTC_3155|Compound:9099265|FD-Score:5.47|P-value:7.70E-5 ID:SGTC_3197|Compound:9113331|FD-Score:21.20|P-value:3.41E-49 ID:SGTC_3200|Compound:9114385|FD-Score:43.30|P-value:1.01E-197 ID:SGTC_3237|Compound:9133362|FD-Score:4.99|P-value:2.78E-4 ID:SGTC_3307|Compound:9126885|FD-Score:7.19|P-value:3.19E-7

Top fitness defect scores for YLR208W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1743 st037606 43.60 46.4 µM 3.97E-201 1 0 21.50
2 SGTC_3200 9114385 43.30 49.5 µM 1.01E-197 1 0 27.50
3 SGTC_2025 5147754 35.10 141.0 µM 1.20E-130 1 1.75E-269 20.70
4 SGTC_786 4544-0069 30.40 423.0 µM 1.30E-98 1 7.50E-203 23.70
5 SGTC_1420 4'-methoxyflavone 25.70 42.0 µM 4.00E-71 1 1.05E-145 19.40
6 SGTC_1416 3966-0321 25.50 25.3 µM 2.05E-70 1 3.16E-144 20.00
7 SGTC_290 2043-6722 22.20 48.1 µM 7.71E-54 1 8.80E-110 17.10
8 SGTC_3197 9113331 21.20 49.5 µM 3.41E-49 1 3.94E-100 9.74
9 SGTC_1655 st012546 20.40 55.1 µM 1.03E-45 1 6.69E-93 15.70
10 SGTC_878 0828-0289 19.80 13.7 µM 3.19E-43 1 9.90E-88 7.88
11 SGTC_993 3909-8757 19.80 62.7 µM 4.42E-43 1 1.96E-87 12.40
12 SGTC_723 4182-0001 19.60 115.0 µM 2.72E-42 1 8.52E-86 15.20
13 SGTC_2756 carbadox 17.90 75.1 µM 1.51E-35 1 8.47E-72 8.70
14 SGTC_138 0850-0259 17.30 40.9 µM 2.68E-33 cell wall 2 3.94E-67 1.97
15 SGTC_1026 k007-1105 16.80 30.6 µM 1.56E-31 ERAD & cell cycle 1 1.82E-63 4.23
16 SGTC_2488 5268135 15.50 45.7 µM 3.43E-27 1 1.84E-54 11.00
17 SGTC_1168 k815-0004 15.50 80.5 µM 3.52E-27 DNA damage response 1 1.94E-54 5.12
18 SGTC_89 0302-0250 14.20 142.1 µM 2.87E-23 1 2.49E-46 9.06
19 SGTC_790 1575-0012 14.10 79.1 µM 5.98E-23 TSC3-RPN4 1 1.13E-45 7.13
20 SGTC_2912 7964298 14.10 10.9 µM 6.58E-23 cell wall 5 1.38E-45 0.16

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.443 1.55E-161 YDL195W SEC31 het Component of the Sec13p-Sec31p complex of the COPII vesicle coat, required for vesicle formation in ER to Golgi transport; mutant has increased aneuploidy tolerance
0.237 3.52E-44 YIL109C SEC24 het Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb2p and Sfb3p
0.136 2.72E-15 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.132 2.05E-14 YDR108W TRS85 hom Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
0.122 1.57E-12 YDR354W TRP4 hom Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
0.115 2.18E-11 YBR156C SLI15 hom Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly
0.115 2.98E-11 YKL211C TRP3 hom Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
0.113 7.11E-11 YHR030C SLT2 hom Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to the phagophore assembly site (PAS); regulated by the PKC1-mediated signaling pathway
0.113 6.18E-11 YLL021W SPA2 hom Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate
0.112 8.35E-11 YDR008C_d YDR008C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.112 1.07E-10 YDR127W ARO1 hom Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
0.107 5.45E-10 YPL066W RGL1 hom Regulator of Rho1p signaling, cofactor of Tus1p; required for the localization of Tus1p during all phases of cytokinesis; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source
0.106 6.38E-10 YKL076C_d PSY1_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 69% of ORF overlaps the uncharacterized ORF YKL075C
0.106 7.35E-10 YJL095W BCK1 hom Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
0.106 8.04E-10 YLR331C_d JIP3_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2