Correlation | pval | ORF | Gene | Zygosity | Description |
---|
0.145 |
3.84E-17 |
YAL066W_d |
YAL066W_d |
hom |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
0.139 |
5.78E-16 |
YHR148W |
IMP3 |
het |
Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA |
0.139 |
7.09E-16 |
YGL152C_d |
YGL152C_d |
hom |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF PEX14/YGL153W |
0.126 |
2.62E-13 |
YMR034C_p |
YMR034C_p |
hom |
Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene |
0.113 |
4.69E-11 |
YPL249C |
GYP5 |
hom |
GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress |
0.111 |
1.17E-10 |
YGL257C |
MNT2 |
hom |
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans |
0.111 |
1.35E-10 |
YDL239C |
ADY3 |
hom |
Protein required for spore wall formation; thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p; ADY3 has a paralog, CNM67, that arose from the whole genome duplication |
0.103 |
1.99E-9 |
YGL149W_d |
YGL149W_d |
hom |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF INO80/YGL150C. |
0.100 |
5.92E-9 |
YKL164C |
PIR1 |
hom |
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle; PIR1 has a paralog, YJL160C, that arose from the whole genome duplication |
0.091 |
1.24E-7 |
YGR286C |
BIO2 |
hom |
Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant |
0.089 |
2.36E-7 |
YGR097W |
ASK10 |
hom |
Component of RNA polymerase II holoenzyme; phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p; proposed to function in activation of the glycerol channel Fps1p; ASK10 has a paralog, RGC1, that arose from the whole genome duplication |
0.089 |
2.80E-7 |
YLR237W |
THI7 |
hom |
Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia |
0.088 |
3.10E-7 |
YGL156W |
AMS1 |
hom |
Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway |
0.086 |
7.04E-7 |
YPR137W |
RRP9 |
het |
Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein |
0.081 |
2.50E-6 |
YOL115W |
PAP2 |
hom |
Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p |