YML071C / COG8

Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

Zygosity: Homozygous strain
fixedexpanded
Profile for YML071C / COG8

Click on Significant Values for Screen Details ID:SGTC_1|Compound:0258-0098|FD-Score:6.72|P-value:2.15E-4 ID:SGTC_4|Compound:0960-0234|FD-Score:6.31|P-value:4.68E-4 ID:SGTC_22|Compound:0964-0034|FD-Score:10.50|P-value:1.72E-8 ID:SGTC_56|Compound:0957-0365|FD-Score:9.89|P-value:1.05E-7 ID:SGTC_59|Compound:0330-0160|FD-Score:6.99|P-value:1.25E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:6.55|P-value:2.96E-4 ID:SGTC_71|Compound:0417-1750|FD-Score:7.29|P-value:6.60E-5 ID:SGTC_79|Compound:0052-0007|FD-Score:8.40|P-value:5.31E-6 ID:SGTC_81|Compound:0411-0046|FD-Score:6.83|P-value:1.70E-4 ID:SGTC_82|Compound:0054-0107|FD-Score:5.93|P-value:9.50E-4 ID:SGTC_91|Compound:0417-1751|FD-Score:11.80|P-value:2.76E-10 ID:SGTC_93|Compound:0109-0045|FD-Score:6.60|P-value:2.73E-4 ID:SGTC_98|Compound:0074-0023|FD-Score:9.63|P-value:2.17E-7 ID:SGTC_102|Compound:gallobenzophenone|FD-Score:7.99|P-value:1.39E-5 ID:SGTC_119|Compound:0121-0043|FD-Score:6.12|P-value:6.64E-4 ID:SGTC_124|Compound:0136-0217|FD-Score:6.40|P-value:3.97E-4 ID:SGTC_275|Compound:trichlorophene|FD-Score:6.66|P-value:2.42E-4 ID:SGTC_329|Compound:k048-0121|FD-Score:6.55|P-value:2.97E-4 ID:SGTC_363|Compound:0455-0021|FD-Score:-6.07|P-value:6.83E-4 ID:SGTC_366|Compound:0181-0206|FD-Score:25.80|P-value:3.37E-42 ID:SGTC_389|Compound:tpck|FD-Score:6.59|P-value:2.75E-4 ID:SGTC_413|Compound:propylparaben|FD-Score:6.48|P-value:3.39E-4 ID:SGTC_430|Compound:0958-0115|FD-Score:10.00|P-value:7.23E-8 ID:SGTC_459|Compound:nigericin|FD-Score:6.72|P-value:2.15E-4 ID:SGTC_470|Compound:aa-861|FD-Score:8.08|P-value:1.13E-5 ID:SGTC_475|Compound:α-linolenic acid|FD-Score:8.01|P-value:1.33E-5 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:13.80|P-value:2.55E-13 ID:SGTC_507|Compound:nimesulide|FD-Score:7.53|P-value:3.93E-5 ID:SGTC_562|Compound:3772-2733|FD-Score:6.66|P-value:2.39E-4 ID:SGTC_566|Compound:0958-0068|FD-Score:6.31|P-value:4.68E-4 ID:SGTC_567|Compound:1080-0542|FD-Score:-5.95|P-value:8.53E-4 ID:SGTC_624|Compound:k048-0052|FD-Score:10.80|P-value:7.25E-9 ID:SGTC_632|Compound:0781-2353|FD-Score:13.80|P-value:2.25E-13 ID:SGTC_679|Compound:0422-0091|FD-Score:6.91|P-value:1.45E-4 ID:SGTC_684|Compound:1140-0066|FD-Score:10.50|P-value:1.57E-8 ID:SGTC_697|Compound:0508-1955|FD-Score:8.00|P-value:1.35E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:6.09|P-value:7.13E-4 ID:SGTC_757|Compound:1066-0008|FD-Score:7.26|P-value:7.03E-5 ID:SGTC_765|Compound:1319-0117|FD-Score:-7.81|P-value:1.94E-5 ID:SGTC_783|Compound:0848-0141|FD-Score:6.16|P-value:6.23E-4 ID:SGTC_798|Compound:1287-0182|FD-Score:6.22|P-value:5.54E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:7.52|P-value:4.01E-5 ID:SGTC_855|Compound:0428-0020|FD-Score:6.73|P-value:2.11E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:7.16|P-value:8.62E-5 ID:SGTC_893|Compound:0958-0369|FD-Score:6.29|P-value:4.88E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:8.35|P-value:5.95E-6 ID:SGTC_1034|Compound:k072-0165|FD-Score:7.29|P-value:6.61E-5 ID:SGTC_1035|Compound:k081-0041|FD-Score:6.39|P-value:4.02E-4 ID:SGTC_1039|Compound:k821-0043|FD-Score:11.40|P-value:1.13E-9 ID:SGTC_1053|Compound:3366-3204|FD-Score:6.37|P-value:4.22E-4 ID:SGTC_1060|Compound:3448-7350|FD-Score:14.70|P-value:5.17E-15 ID:SGTC_1068|Compound:loratadine|FD-Score:6.82|P-value:1.76E-4 ID:SGTC_1078|Compound:idebenone|FD-Score:13.00|P-value:4.37E-12 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:7.70|P-value:2.72E-5 ID:SGTC_1139|Compound:k015-0024|FD-Score:7.03|P-value:1.15E-4 ID:SGTC_1162|Compound:k048-0130|FD-Score:9.73|P-value:1.66E-7 ID:SGTC_1306|Compound:1185-0270|FD-Score:18.90|P-value:1.53E-23 ID:SGTC_1353|Compound:1498-1206|FD-Score:7.26|P-value:7.02E-5 ID:SGTC_1363|Compound:1636-0063|FD-Score:8.74|P-value:2.29E-6 ID:SGTC_1367|Compound:1812-0510|FD-Score:6.27|P-value:5.07E-4 ID:SGTC_1376|Compound:2910-0861|FD-Score:6.91|P-value:1.45E-4 ID:SGTC_1408|Compound:3909-7976|FD-Score:6.06|P-value:7.41E-4 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:6.87|P-value:1.58E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:9.83|P-value:1.24E-7 ID:SGTC_1669|Compound:st015249|FD-Score:5.91|P-value:9.83E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.10|P-value:2.55E-9 ID:SGTC_1723|Compound:st034307|FD-Score:6.02|P-value:8.01E-4 ID:SGTC_1735|Compound:st034310|FD-Score:7.16|P-value:8.79E-5 ID:SGTC_1751|Compound:st044839|FD-Score:5.95|P-value:9.08E-4 ID:SGTC_1772|Compound:st048439|FD-Score:7.16|P-value:8.69E-5 ID:SGTC_1775|Compound:st081588|FD-Score:10.90|P-value:6.02E-9 ID:SGTC_1783|Compound:st039459|FD-Score:12.50|P-value:2.75E-11 ID:SGTC_1789|Compound:tunicamycin|FD-Score:6.58|P-value:2.83E-4 ID:SGTC_1797|Compound:st048695|FD-Score:-6.54|P-value:2.82E-4 ID:SGTC_1815|Compound:st051655|FD-Score:7.65|P-value:3.05E-5 ID:SGTC_1818|Compound:st052136|FD-Score:-6.00|P-value:7.76E-4 ID:SGTC_1824|Compound:st053723|FD-Score:6.24|P-value:5.41E-4 ID:SGTC_1870|Compound:st057514|FD-Score:7.66|P-value:2.97E-5 ID:SGTC_1917|Compound:st066507|FD-Score:8.71|P-value:2.47E-6 ID:SGTC_1999|Compound:st074831|FD-Score:-6.48|P-value:3.16E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-6.95|P-value:1.24E-4 ID:SGTC_2041|Compound:5107442|FD-Score:10.00|P-value:7.51E-8 ID:SGTC_2187|Compound:6125751|FD-Score:6.76|P-value:1.96E-4 ID:SGTC_2194|Compound:5927483|FD-Score:6.16|P-value:6.17E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:6.65|P-value:2.44E-4 ID:SGTC_2242|Compound:6630449|FD-Score:12.80|P-value:9.06E-12 ID:SGTC_2255|Compound:7941087|FD-Score:6.20|P-value:5.74E-4 ID:SGTC_2346|Compound:9031566|FD-Score:7.13|P-value:9.30E-5 ID:SGTC_2396|Compound:5342950|FD-Score:6.45|P-value:3.59E-4 ID:SGTC_2443|Compound:5493264|FD-Score:5.95|P-value:9.18E-4 ID:SGTC_2444|Compound:5485484|FD-Score:6.03|P-value:7.92E-4 ID:SGTC_2472|Compound:5377652|FD-Score:6.73|P-value:2.08E-4 ID:SGTC_2552|Compound:juarezic acid|FD-Score:6.07|P-value:7.34E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:6.79|P-value:1.86E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.94|P-value:1.37E-4 ID:SGTC_2671|Compound:danthron|FD-Score:6.56|P-value:2.94E-4 ID:SGTC_2737|Compound:bleomycin|FD-Score:18.20|P-value:6.02E-22 ID:SGTC_2740|Compound:felodipine|FD-Score:6.11|P-value:6.78E-4 ID:SGTC_2766|Compound:oltipraz|FD-Score:26.80|P-value:2.26E-45 ID:SGTC_2770|Compound:toltrazuril|FD-Score:8.05|P-value:1.22E-5 ID:SGTC_2777|Compound:climbazole|FD-Score:-7.81|P-value:1.91E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:-7.94|P-value:1.44E-5 ID:SGTC_2800|Compound:7887935|FD-Score:6.55|P-value:3.01E-4 ID:SGTC_2838|Compound:9002687|FD-Score:-7.38|P-value:5.06E-5 ID:SGTC_2845|Compound:9003024|FD-Score:6.78|P-value:1.89E-4 ID:SGTC_2890|Compound:9046729|FD-Score:6.99|P-value:1.25E-4 ID:SGTC_2900|Compound:5328528|FD-Score:9.92|P-value:9.73E-8 ID:SGTC_2902|Compound:5787006|FD-Score:6.37|P-value:4.17E-4 ID:SGTC_2923|Compound:7992654|FD-Score:5.93|P-value:9.41E-4 ID:SGTC_2944|Compound:9067346|FD-Score:-5.96|P-value:8.36E-4 ID:SGTC_2948|Compound:9070189|FD-Score:-6.79|P-value:1.70E-4 ID:SGTC_2950|Compound:9072895|FD-Score:-7.10|P-value:9.07E-5 ID:SGTC_2981|Compound:9013952|FD-Score:8.04|P-value:1.25E-5 ID:SGTC_3054|Compound:9094397|FD-Score:-6.88|P-value:1.44E-4 ID:SGTC_3057|Compound:9095946|FD-Score:9.02|P-value:1.12E-6 ID:SGTC_3062|Compound:9077494|FD-Score:7.36|P-value:5.64E-5 ID:SGTC_3126|Compound:9127922|FD-Score:-6.66|P-value:2.22E-4 ID:SGTC_3166|Compound:9102297|FD-Score:9.36|P-value:4.51E-7 ID:SGTC_3187|Compound:9109394|FD-Score:6.75|P-value:2.02E-4 ID:SGTC_3219|Compound:9131112|FD-Score:9.00|P-value:1.17E-6 ID:SGTC_3235|Compound:9132602|FD-Score:6.14|P-value:6.48E-4 ID:SGTC_3277|Compound:9138724|FD-Score:12.20|P-value:7.08E-11 ID:SGTC_3321|Compound:9137793|FD-Score:5.92|P-value:9.55E-4 ID:SGTC_3325|Compound:9138760|FD-Score:11.20|P-value:2.06E-9 ID:SGTC_1|Compound:0258-0098|FD-Score:6.72|P-value:2.15E-4 ID:SGTC_4|Compound:0960-0234|FD-Score:6.31|P-value:4.68E-4 ID:SGTC_22|Compound:0964-0034|FD-Score:10.50|P-value:1.72E-8 ID:SGTC_56|Compound:0957-0365|FD-Score:9.89|P-value:1.05E-7 ID:SGTC_59|Compound:0330-0160|FD-Score:6.99|P-value:1.25E-4 ID:SGTC_70|Compound:0141-0289|FD-Score:6.55|P-value:2.96E-4 ID:SGTC_71|Compound:0417-1750|FD-Score:7.29|P-value:6.60E-5 ID:SGTC_79|Compound:0052-0007|FD-Score:8.40|P-value:5.31E-6 ID:SGTC_81|Compound:0411-0046|FD-Score:6.83|P-value:1.70E-4 ID:SGTC_82|Compound:0054-0107|FD-Score:5.93|P-value:9.50E-4 ID:SGTC_91|Compound:0417-1751|FD-Score:11.80|P-value:2.76E-10 ID:SGTC_93|Compound:0109-0045|FD-Score:6.60|P-value:2.73E-4 ID:SGTC_98|Compound:0074-0023|FD-Score:9.63|P-value:2.17E-7 ID:SGTC_102|Compound:gallobenzophenone|FD-Score:7.99|P-value:1.39E-5 ID:SGTC_119|Compound:0121-0043|FD-Score:6.12|P-value:6.64E-4 ID:SGTC_124|Compound:0136-0217|FD-Score:6.40|P-value:3.97E-4 ID:SGTC_275|Compound:trichlorophene|FD-Score:6.66|P-value:2.42E-4 ID:SGTC_329|Compound:k048-0121|FD-Score:6.55|P-value:2.97E-4 ID:SGTC_363|Compound:0455-0021|FD-Score:-6.07|P-value:6.83E-4 ID:SGTC_366|Compound:0181-0206|FD-Score:25.80|P-value:3.37E-42 ID:SGTC_389|Compound:tpck|FD-Score:6.59|P-value:2.75E-4 ID:SGTC_413|Compound:propylparaben|FD-Score:6.48|P-value:3.39E-4 ID:SGTC_430|Compound:0958-0115|FD-Score:10.00|P-value:7.23E-8 ID:SGTC_459|Compound:nigericin|FD-Score:6.72|P-value:2.15E-4 ID:SGTC_470|Compound:aa-861|FD-Score:8.08|P-value:1.13E-5 ID:SGTC_475|Compound:α-linolenic acid|FD-Score:8.01|P-value:1.33E-5 ID:SGTC_498|Compound:2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ)|FD-Score:13.80|P-value:2.55E-13 ID:SGTC_507|Compound:nimesulide|FD-Score:7.53|P-value:3.93E-5 ID:SGTC_562|Compound:3772-2733|FD-Score:6.66|P-value:2.39E-4 ID:SGTC_566|Compound:0958-0068|FD-Score:6.31|P-value:4.68E-4 ID:SGTC_567|Compound:1080-0542|FD-Score:-5.95|P-value:8.53E-4 ID:SGTC_624|Compound:k048-0052|FD-Score:10.80|P-value:7.25E-9 ID:SGTC_632|Compound:0781-2353|FD-Score:13.80|P-value:2.25E-13 ID:SGTC_679|Compound:0422-0091|FD-Score:6.91|P-value:1.45E-4 ID:SGTC_684|Compound:1140-0066|FD-Score:10.50|P-value:1.57E-8 ID:SGTC_697|Compound:0508-1955|FD-Score:8.00|P-value:1.35E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:6.09|P-value:7.13E-4 ID:SGTC_757|Compound:1066-0008|FD-Score:7.26|P-value:7.03E-5 ID:SGTC_765|Compound:1319-0117|FD-Score:-7.81|P-value:1.94E-5 ID:SGTC_783|Compound:0848-0141|FD-Score:6.16|P-value:6.23E-4 ID:SGTC_798|Compound:1287-0182|FD-Score:6.22|P-value:5.54E-4 ID:SGTC_852|Compound:0418-0143|FD-Score:7.52|P-value:4.01E-5 ID:SGTC_855|Compound:0428-0020|FD-Score:6.73|P-value:2.11E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:7.16|P-value:8.62E-5 ID:SGTC_893|Compound:0958-0369|FD-Score:6.29|P-value:4.88E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:8.35|P-value:5.95E-6 ID:SGTC_1034|Compound:k072-0165|FD-Score:7.29|P-value:6.61E-5 ID:SGTC_1035|Compound:k081-0041|FD-Score:6.39|P-value:4.02E-4 ID:SGTC_1039|Compound:k821-0043|FD-Score:11.40|P-value:1.13E-9 ID:SGTC_1053|Compound:3366-3204|FD-Score:6.37|P-value:4.22E-4 ID:SGTC_1060|Compound:3448-7350|FD-Score:14.70|P-value:5.17E-15 ID:SGTC_1068|Compound:loratadine|FD-Score:6.82|P-value:1.76E-4 ID:SGTC_1078|Compound:idebenone|FD-Score:13.00|P-value:4.37E-12 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:7.70|P-value:2.72E-5 ID:SGTC_1139|Compound:k015-0024|FD-Score:7.03|P-value:1.15E-4 ID:SGTC_1162|Compound:k048-0130|FD-Score:9.73|P-value:1.66E-7 ID:SGTC_1306|Compound:1185-0270|FD-Score:18.90|P-value:1.53E-23 ID:SGTC_1353|Compound:1498-1206|FD-Score:7.26|P-value:7.02E-5 ID:SGTC_1363|Compound:1636-0063|FD-Score:8.74|P-value:2.29E-6 ID:SGTC_1367|Compound:1812-0510|FD-Score:6.27|P-value:5.07E-4 ID:SGTC_1376|Compound:2910-0861|FD-Score:6.91|P-value:1.45E-4 ID:SGTC_1408|Compound:3909-7976|FD-Score:6.06|P-value:7.41E-4 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:6.87|P-value:1.58E-4 ID:SGTC_1581|Compound:himbacine|FD-Score:9.83|P-value:1.24E-7 ID:SGTC_1669|Compound:st015249|FD-Score:5.91|P-value:9.83E-4 ID:SGTC_1679|Compound:4130-1276|FD-Score:11.10|P-value:2.55E-9 ID:SGTC_1723|Compound:st034307|FD-Score:6.02|P-value:8.01E-4 ID:SGTC_1735|Compound:st034310|FD-Score:7.16|P-value:8.79E-5 ID:SGTC_1751|Compound:st044839|FD-Score:5.95|P-value:9.08E-4 ID:SGTC_1772|Compound:st048439|FD-Score:7.16|P-value:8.69E-5 ID:SGTC_1775|Compound:st081588|FD-Score:10.90|P-value:6.02E-9 ID:SGTC_1783|Compound:st039459|FD-Score:12.50|P-value:2.75E-11 ID:SGTC_1789|Compound:tunicamycin|FD-Score:6.58|P-value:2.83E-4 ID:SGTC_1797|Compound:st048695|FD-Score:-6.54|P-value:2.82E-4 ID:SGTC_1815|Compound:st051655|FD-Score:7.65|P-value:3.05E-5 ID:SGTC_1818|Compound:st052136|FD-Score:-6.00|P-value:7.76E-4 ID:SGTC_1824|Compound:st053723|FD-Score:6.24|P-value:5.41E-4 ID:SGTC_1870|Compound:st057514|FD-Score:7.66|P-value:2.97E-5 ID:SGTC_1917|Compound:st066507|FD-Score:8.71|P-value:2.47E-6 ID:SGTC_1999|Compound:st074831|FD-Score:-6.48|P-value:3.16E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-6.95|P-value:1.24E-4 ID:SGTC_2041|Compound:5107442|FD-Score:10.00|P-value:7.51E-8 ID:SGTC_2187|Compound:6125751|FD-Score:6.76|P-value:1.96E-4 ID:SGTC_2194|Compound:5927483|FD-Score:6.16|P-value:6.17E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:6.65|P-value:2.44E-4 ID:SGTC_2242|Compound:6630449|FD-Score:12.80|P-value:9.06E-12 ID:SGTC_2255|Compound:7941087|FD-Score:6.20|P-value:5.74E-4 ID:SGTC_2346|Compound:9031566|FD-Score:7.13|P-value:9.30E-5 ID:SGTC_2396|Compound:5342950|FD-Score:6.45|P-value:3.59E-4 ID:SGTC_2443|Compound:5493264|FD-Score:5.95|P-value:9.18E-4 ID:SGTC_2444|Compound:5485484|FD-Score:6.03|P-value:7.92E-4 ID:SGTC_2472|Compound:5377652|FD-Score:6.73|P-value:2.08E-4 ID:SGTC_2552|Compound:juarezic acid|FD-Score:6.07|P-value:7.34E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:6.79|P-value:1.86E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:6.94|P-value:1.37E-4 ID:SGTC_2671|Compound:danthron|FD-Score:6.56|P-value:2.94E-4 ID:SGTC_2737|Compound:bleomycin|FD-Score:18.20|P-value:6.02E-22 ID:SGTC_2740|Compound:felodipine|FD-Score:6.11|P-value:6.78E-4 ID:SGTC_2766|Compound:oltipraz|FD-Score:26.80|P-value:2.26E-45 ID:SGTC_2770|Compound:toltrazuril|FD-Score:8.05|P-value:1.22E-5 ID:SGTC_2777|Compound:climbazole|FD-Score:-7.81|P-value:1.91E-5 ID:SGTC_2778|Compound:tioconazole|FD-Score:-7.94|P-value:1.44E-5 ID:SGTC_2800|Compound:7887935|FD-Score:6.55|P-value:3.01E-4 ID:SGTC_2838|Compound:9002687|FD-Score:-7.38|P-value:5.06E-5 ID:SGTC_2845|Compound:9003024|FD-Score:6.78|P-value:1.89E-4 ID:SGTC_2890|Compound:9046729|FD-Score:6.99|P-value:1.25E-4 ID:SGTC_2900|Compound:5328528|FD-Score:9.92|P-value:9.73E-8 ID:SGTC_2902|Compound:5787006|FD-Score:6.37|P-value:4.17E-4 ID:SGTC_2923|Compound:7992654|FD-Score:5.93|P-value:9.41E-4 ID:SGTC_2944|Compound:9067346|FD-Score:-5.96|P-value:8.36E-4 ID:SGTC_2948|Compound:9070189|FD-Score:-6.79|P-value:1.70E-4 ID:SGTC_2950|Compound:9072895|FD-Score:-7.10|P-value:9.07E-5 ID:SGTC_2981|Compound:9013952|FD-Score:8.04|P-value:1.25E-5 ID:SGTC_3054|Compound:9094397|FD-Score:-6.88|P-value:1.44E-4 ID:SGTC_3057|Compound:9095946|FD-Score:9.02|P-value:1.12E-6 ID:SGTC_3062|Compound:9077494|FD-Score:7.36|P-value:5.64E-5 ID:SGTC_3126|Compound:9127922|FD-Score:-6.66|P-value:2.22E-4 ID:SGTC_3166|Compound:9102297|FD-Score:9.36|P-value:4.51E-7 ID:SGTC_3187|Compound:9109394|FD-Score:6.75|P-value:2.02E-4 ID:SGTC_3219|Compound:9131112|FD-Score:9.00|P-value:1.17E-6 ID:SGTC_3235|Compound:9132602|FD-Score:6.14|P-value:6.48E-4 ID:SGTC_3277|Compound:9138724|FD-Score:12.20|P-value:7.08E-11 ID:SGTC_3321|Compound:9137793|FD-Score:5.92|P-value:9.55E-4 ID:SGTC_3325|Compound:9138760|FD-Score:11.20|P-value:2.06E-9

Top fitness defect scores for YML071C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2766 oltipraz 26.80 83.9 µM 2.26E-45 heme requiring 1 1.04E-158
2 SGTC_366 0181-0206 25.80 4.3 µM 3.37E-42 Golgi 1 2.94E-147
3 SGTC_1306 1185-0270 18.90 9.0 µM 1.53E-23 Golgi 3 4.83E-80
4 SGTC_2737 bleomycin 18.20 30.5 nM 6.02E-22 Golgi 1 2.60E-74
5 SGTC_1060 3448-7350 14.70 82.0 µM 5.17E-15 Golgi 2 1.99E-49
6 SGTC_632 0781-2353 13.80 4.7 µM 2.25E-13 Golgi 2 1.47E-43
7 SGTC_498 2,5-di-tert-butyl-1,4-hydroquinone (DTBHQ) 13.80 150.0 µM 2.55E-13 Golgi 1 2.27E-43
8 SGTC_1078 idebenone 13.00 36.1 µM 4.37E-12 Golgi 2 5.88E-39
9 SGTC_2242 6630449 12.80 61.3 µM 9.06E-12 Golgi 4 7.93E-38
10 SGTC_1783 st039459 12.50 87.5 µM 2.75E-11 Golgi 1 4.14E-36
11 SGTC_3277 9138724 12.20 49.5 µM 7.08E-11 Golgi 1 1.22E-34
12 SGTC_91 0417-1751 11.80 58.4 µM 2.76E-10 Golgi 4 1.56E-32
13 SGTC_1039 k821-0043 11.40 94.0 µM 1.13E-9 Golgi 1 2.33E-30
14 SGTC_3325 9138760 11.20 55.2 µM 2.06E-9 Golgi 2 1.96E-29
15 SGTC_1679 4130-1276 11.10 6.7 µM 2.55E-9 Golgi 7 4.22E-29
16 SGTC_1775 st081588 10.90 35.2 µM 6.02E-9 60S ribosome export 1 8.94E-28
17 SGTC_624 k048-0052 10.80 28.0 µM 7.25E-9 Golgi 1 1.72E-27
18 SGTC_684 1140-0066 10.50 328.0 µM 1.57E-8 Golgi 1 2.66E-26
19 SGTC_22 0964-0034 10.50 14.5 µM 1.72E-8 unfolded protein response 6 3.72E-26
20 SGTC_430 0958-0115 10.00 16.4 µM 7.23E-8 1 6.01E-24

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.609 0 YGL005C COG7 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.527 3.87E-239 YNL041C COG6 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.453 1.03E-168 YKR019C IRS4 hom EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
0.402 2.24E-130 YJL004C SYS1 hom Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation
0.356 2.23E-100 YNL051W COG5 hom Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
0.353 2.32E-99 YBR164C ARL1 hom Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
0.339 5.19E-91 YPL051W ARL3 hom GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
0.326 9.37E-84 YDR136C_d VPS61_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 4% of ORF overlaps the verified gene RGP1; deletion causes a vacuolar protein sorting defect
0.296 7.61E-69 YLR262C YPT6 hom Rab family GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6
0.294 1.73E-67 YOL018C TLG2 hom Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)
0.286 2.34E-64 YDR108W TRS85 hom Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
0.279 5.53E-61 YDR137W RGP1 hom Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p
0.270 4.47E-57 YLR261C_d VPS63_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene YPT6; deletion causes a vacuolar protein sorting defect
0.244 1.28E-46 YLR039C RIC1 hom Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes
0.205 2.61E-33 YDR320C SWA2 hom Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles