YML094C-A_d

Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO

Zygosity: Homozygous strain
fixedexpanded
Profile for YML094C-A / YML094C-A

Click on Significant Values for Screen Details ID:SGTC_6|Compound:0844-0013|FD-Score:4.15|P-value:5.91E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:9.67|P-value:3.37E-19 ID:SGTC_146|Compound:3448-8650|FD-Score:8.51|P-value:2.59E-15 ID:SGTC_149|Compound:3970-0822|FD-Score:5.22|P-value:7.10E-7 ID:SGTC_163|Compound:1327-0036|FD-Score:6.65|P-value:4.48E-10 ID:SGTC_212|Compound:3807-4682|FD-Score:6.21|P-value:5.16E-9 ID:SGTC_221|Compound:trifluoperazine|FD-Score:12.60|P-value:3.88E-31 ID:SGTC_232|Compound:clozapine|FD-Score:4.45|P-value:1.90E-5 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:4.73|P-value:6.20E-6 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:8.28|P-value:1.38E-14 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:11.80|P-value:8.98E-28 ID:SGTC_242|Compound:5hr heat shock (37°C) + 5-fluorouracil|FD-Score:7.70|P-value:7.21E-13 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:4.88|P-value:3.21E-6 ID:SGTC_301|Compound:4119-0100|FD-Score:8.01|P-value:8.96E-14 ID:SGTC_313|Compound:3474-0040|FD-Score:4.84|P-value:3.74E-6 ID:SGTC_408|Compound:cantharidin|FD-Score:5.05|P-value:1.50E-6 ID:SGTC_428|Compound:3448-4153|FD-Score:3.34|P-value:9.56E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:8.62|P-value:1.16E-15 ID:SGTC_447|Compound:ml7|FD-Score:5.91|P-value:2.46E-8 ID:SGTC_449|Compound:xestospongin c|FD-Score:4.31|P-value:3.30E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.42|P-value:5.45E-7 ID:SGTC_467|Compound:ro 31-8220|FD-Score:6.98|P-value:6.59E-11 ID:SGTC_473|Compound:2-arachidonoylglycerol|FD-Score:7.49|P-value:2.69E-12 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:3.60|P-value:4.07E-4 ID:SGTC_486|Compound:niguldipine|FD-Score:-3.95|P-value:2.02E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-3.72|P-value:4.40E-4 ID:SGTC_516|Compound:3992-2719|FD-Score:3.39|P-value:8.07E-4 ID:SGTC_535|Compound:2293-4129|FD-Score:8.40|P-value:5.74E-15 ID:SGTC_586|Compound:0957-0265|FD-Score:3.76|P-value:2.42E-4 ID:SGTC_663|Compound:1486-0733|FD-Score:6.03|P-value:1.35E-8 ID:SGTC_771|Compound:0250-0039|FD-Score:3.61|P-value:3.94E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:3.73|P-value:2.65E-4 ID:SGTC_940|Compound:3232-1287|FD-Score:4.37|P-value:2.63E-5 ID:SGTC_1045|Compound:1348-1485|FD-Score:3.38|P-value:8.33E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:-3.66|P-value:5.34E-4 ID:SGTC_1087|Compound:pterostilbene|FD-Score:3.67|P-value:3.31E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:8.78|P-value:3.58E-16 ID:SGTC_1196|Compound:1588-0294|FD-Score:5.34|P-value:4.12E-7 ID:SGTC_1249|Compound:0481-0015|FD-Score:3.51|P-value:5.51E-4 ID:SGTC_1292|Compound:0kpi-0043|FD-Score:3.89|P-value:1.56E-4 ID:SGTC_1360|Compound:1598-0022|FD-Score:3.87|P-value:1.63E-4 ID:SGTC_1419|Compound:3993-2473|FD-Score:3.78|P-value:2.22E-4 ID:SGTC_1512|Compound:0259-0544|FD-Score:3.37|P-value:8.56E-4 ID:SGTC_1524|Compound:corynanthine|FD-Score:-4.12|P-value:1.12E-4 ID:SGTC_1643|Compound:st009866|FD-Score:6.35|P-value:2.41E-9 ID:SGTC_1712|Compound:st032288|FD-Score:8.35|P-value:8.14E-15 ID:SGTC_1754|Compound:st042065|FD-Score:4.25|P-value:4.11E-5 ID:SGTC_1760|Compound:st045453|FD-Score:9.38|P-value:3.49E-18 ID:SGTC_1773|Compound:st048542|FD-Score:3.60|P-value:4.15E-4 ID:SGTC_1781|Compound:st038725|FD-Score:4.30|P-value:3.41E-5 ID:SGTC_1797|Compound:st048695|FD-Score:3.52|P-value:5.27E-4 ID:SGTC_1800|Compound:st050079|FD-Score:3.35|P-value:9.04E-4 ID:SGTC_1801|Compound:st050089|FD-Score:3.43|P-value:7.10E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.08|P-value:1.03E-8 ID:SGTC_1844|Compound:rapamycin|FD-Score:7.29|P-value:9.75E-12 ID:SGTC_1875|Compound:nocodazole|FD-Score:10.10|P-value:9.30E-21 ID:SGTC_1877|Compound:wortmannin|FD-Score:5.35|P-value:3.98E-7 ID:SGTC_1902|Compound:st060212|FD-Score:4.44|P-value:1.94E-5 ID:SGTC_1904|Compound:st060225|FD-Score:4.08|P-value:7.63E-5 ID:SGTC_1911|Compound:st060208|FD-Score:5.86|P-value:3.28E-8 ID:SGTC_1981|Compound:st071826|FD-Score:5.72|P-value:6.46E-8 ID:SGTC_1991|Compound:st073000|FD-Score:5.05|P-value:1.56E-6 ID:SGTC_2007|Compound:4011539|FD-Score:3.93|P-value:1.35E-4 ID:SGTC_2036|Compound:5160441|FD-Score:4.54|P-value:1.35E-5 ID:SGTC_2051|Compound:5263410|FD-Score:5.19|P-value:8.22E-7 ID:SGTC_2085|Compound:5307070|FD-Score:3.38|P-value:8.25E-4 ID:SGTC_2089|Compound:5281248|FD-Score:3.69|P-value:3.03E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.16|P-value:9.39E-7 ID:SGTC_2329|Compound:6138490|FD-Score:-3.50|P-value:8.79E-4 ID:SGTC_2339|Compound:9000433|FD-Score:4.15|P-value:5.92E-5 ID:SGTC_2396|Compound:5342950|FD-Score:4.14|P-value:6.21E-5 ID:SGTC_2399|Compound:5884133|FD-Score:5.55|P-value:1.48E-7 ID:SGTC_2465|Compound:5809242|FD-Score:3.55|P-value:4.86E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:3.64|P-value:3.60E-4 ID:SGTC_2615|Compound:purpurogallin-4-carboxylic acid|FD-Score:4.47|P-value:1.72E-5 ID:SGTC_2616|Compound:abietic acid|FD-Score:3.90|P-value:1.48E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:3.82|P-value:1.93E-4 ID:SGTC_2679|Compound:rapamycin|FD-Score:4.67|P-value:7.72E-6 ID:SGTC_2688|Compound:kanamycin b|FD-Score:4.40|P-value:2.29E-5 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:4.61|P-value:1.00E-5 ID:SGTC_2790|Compound:5423970|FD-Score:4.42|P-value:2.11E-5 ID:SGTC_2796|Compound:7949634|FD-Score:-4.53|P-value:2.38E-5 ID:SGTC_2855|Compound:9016525|FD-Score:3.33|P-value:9.76E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-6.13|P-value:1.67E-8 ID:SGTC_3037|Compound:9091026|FD-Score:5.87|P-value:3.02E-8 ID:SGTC_3152|Compound:9099253|FD-Score:4.29|P-value:3.47E-5 ID:SGTC_3219|Compound:9131112|FD-Score:-4.03|P-value:1.50E-4 ID:SGTC_6|Compound:0844-0013|FD-Score:4.15|P-value:5.91E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:9.67|P-value:3.37E-19 ID:SGTC_146|Compound:3448-8650|FD-Score:8.51|P-value:2.59E-15 ID:SGTC_149|Compound:3970-0822|FD-Score:5.22|P-value:7.10E-7 ID:SGTC_163|Compound:1327-0036|FD-Score:6.65|P-value:4.48E-10 ID:SGTC_212|Compound:3807-4682|FD-Score:6.21|P-value:5.16E-9 ID:SGTC_221|Compound:trifluoperazine|FD-Score:12.60|P-value:3.88E-31 ID:SGTC_232|Compound:clozapine|FD-Score:4.45|P-value:1.90E-5 ID:SGTC_239|Compound:5hr heat shock (37°C) + mitomycin C|FD-Score:4.73|P-value:6.20E-6 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:8.28|P-value:1.38E-14 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:11.80|P-value:8.98E-28 ID:SGTC_242|Compound:5hr heat shock (37°C) + 5-fluorouracil|FD-Score:7.70|P-value:7.21E-13 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:4.88|P-value:3.21E-6 ID:SGTC_301|Compound:4119-0100|FD-Score:8.01|P-value:8.96E-14 ID:SGTC_313|Compound:3474-0040|FD-Score:4.84|P-value:3.74E-6 ID:SGTC_408|Compound:cantharidin|FD-Score:5.05|P-value:1.50E-6 ID:SGTC_428|Compound:3448-4153|FD-Score:3.34|P-value:9.56E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:8.62|P-value:1.16E-15 ID:SGTC_447|Compound:ml7|FD-Score:5.91|P-value:2.46E-8 ID:SGTC_449|Compound:xestospongin c|FD-Score:4.31|P-value:3.30E-5 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.42|P-value:5.45E-7 ID:SGTC_467|Compound:ro 31-8220|FD-Score:6.98|P-value:6.59E-11 ID:SGTC_473|Compound:2-arachidonoylglycerol|FD-Score:7.49|P-value:2.69E-12 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:3.60|P-value:4.07E-4 ID:SGTC_486|Compound:niguldipine|FD-Score:-3.95|P-value:2.02E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-3.72|P-value:4.40E-4 ID:SGTC_516|Compound:3992-2719|FD-Score:3.39|P-value:8.07E-4 ID:SGTC_535|Compound:2293-4129|FD-Score:8.40|P-value:5.74E-15 ID:SGTC_586|Compound:0957-0265|FD-Score:3.76|P-value:2.42E-4 ID:SGTC_663|Compound:1486-0733|FD-Score:6.03|P-value:1.35E-8 ID:SGTC_771|Compound:0250-0039|FD-Score:3.61|P-value:3.94E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:3.73|P-value:2.65E-4 ID:SGTC_940|Compound:3232-1287|FD-Score:4.37|P-value:2.63E-5 ID:SGTC_1045|Compound:1348-1485|FD-Score:3.38|P-value:8.33E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:-3.66|P-value:5.34E-4 ID:SGTC_1087|Compound:pterostilbene|FD-Score:3.67|P-value:3.31E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:8.78|P-value:3.58E-16 ID:SGTC_1196|Compound:1588-0294|FD-Score:5.34|P-value:4.12E-7 ID:SGTC_1249|Compound:0481-0015|FD-Score:3.51|P-value:5.51E-4 ID:SGTC_1292|Compound:0kpi-0043|FD-Score:3.89|P-value:1.56E-4 ID:SGTC_1360|Compound:1598-0022|FD-Score:3.87|P-value:1.63E-4 ID:SGTC_1419|Compound:3993-2473|FD-Score:3.78|P-value:2.22E-4 ID:SGTC_1512|Compound:0259-0544|FD-Score:3.37|P-value:8.56E-4 ID:SGTC_1524|Compound:corynanthine|FD-Score:-4.12|P-value:1.12E-4 ID:SGTC_1643|Compound:st009866|FD-Score:6.35|P-value:2.41E-9 ID:SGTC_1712|Compound:st032288|FD-Score:8.35|P-value:8.14E-15 ID:SGTC_1754|Compound:st042065|FD-Score:4.25|P-value:4.11E-5 ID:SGTC_1760|Compound:st045453|FD-Score:9.38|P-value:3.49E-18 ID:SGTC_1773|Compound:st048542|FD-Score:3.60|P-value:4.15E-4 ID:SGTC_1781|Compound:st038725|FD-Score:4.30|P-value:3.41E-5 ID:SGTC_1797|Compound:st048695|FD-Score:3.52|P-value:5.27E-4 ID:SGTC_1800|Compound:st050079|FD-Score:3.35|P-value:9.04E-4 ID:SGTC_1801|Compound:st050089|FD-Score:3.43|P-value:7.10E-4 ID:SGTC_1803|Compound:st050068|FD-Score:6.08|P-value:1.03E-8 ID:SGTC_1844|Compound:rapamycin|FD-Score:7.29|P-value:9.75E-12 ID:SGTC_1875|Compound:nocodazole|FD-Score:10.10|P-value:9.30E-21 ID:SGTC_1877|Compound:wortmannin|FD-Score:5.35|P-value:3.98E-7 ID:SGTC_1902|Compound:st060212|FD-Score:4.44|P-value:1.94E-5 ID:SGTC_1904|Compound:st060225|FD-Score:4.08|P-value:7.63E-5 ID:SGTC_1911|Compound:st060208|FD-Score:5.86|P-value:3.28E-8 ID:SGTC_1981|Compound:st071826|FD-Score:5.72|P-value:6.46E-8 ID:SGTC_1991|Compound:st073000|FD-Score:5.05|P-value:1.56E-6 ID:SGTC_2007|Compound:4011539|FD-Score:3.93|P-value:1.35E-4 ID:SGTC_2036|Compound:5160441|FD-Score:4.54|P-value:1.35E-5 ID:SGTC_2051|Compound:5263410|FD-Score:5.19|P-value:8.22E-7 ID:SGTC_2085|Compound:5307070|FD-Score:3.38|P-value:8.25E-4 ID:SGTC_2089|Compound:5281248|FD-Score:3.69|P-value:3.03E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.16|P-value:9.39E-7 ID:SGTC_2329|Compound:6138490|FD-Score:-3.50|P-value:8.79E-4 ID:SGTC_2339|Compound:9000433|FD-Score:4.15|P-value:5.92E-5 ID:SGTC_2396|Compound:5342950|FD-Score:4.14|P-value:6.21E-5 ID:SGTC_2399|Compound:5884133|FD-Score:5.55|P-value:1.48E-7 ID:SGTC_2465|Compound:5809242|FD-Score:3.55|P-value:4.86E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:3.64|P-value:3.60E-4 ID:SGTC_2615|Compound:purpurogallin-4-carboxylic acid|FD-Score:4.47|P-value:1.72E-5 ID:SGTC_2616|Compound:abietic acid|FD-Score:3.90|P-value:1.48E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:3.82|P-value:1.93E-4 ID:SGTC_2679|Compound:rapamycin|FD-Score:4.67|P-value:7.72E-6 ID:SGTC_2688|Compound:kanamycin b|FD-Score:4.40|P-value:2.29E-5 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:4.61|P-value:1.00E-5 ID:SGTC_2790|Compound:5423970|FD-Score:4.42|P-value:2.11E-5 ID:SGTC_2796|Compound:7949634|FD-Score:-4.53|P-value:2.38E-5 ID:SGTC_2855|Compound:9016525|FD-Score:3.33|P-value:9.76E-4 ID:SGTC_2858|Compound:9025781|FD-Score:-6.13|P-value:1.67E-8 ID:SGTC_3037|Compound:9091026|FD-Score:5.87|P-value:3.02E-8 ID:SGTC_3152|Compound:9099253|FD-Score:4.29|P-value:3.47E-5 ID:SGTC_3219|Compound:9131112|FD-Score:-4.03|P-value:1.50E-4

Top fitness defect scores for YML094C-A deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_221 trifluoperazine 12.60 10.3 µM 3.88E-31 NEO1-PIK1 35 1.13E-36
2 SGTC_241 5hr heat shock (37°C) + cantharidin 11.80 155.4 µM 8.98E-28 cell wall signaling 9 1.18E-32
3 SGTC_1875 nocodazole 10.10 6.0 µM 9.30E-21 tubulin folding & SWR complex 15 2.80E-24
4 SGTC_58 0957-0393 9.67 9.0 µM 3.37E-19 cell wall 88 2.02E-22
5 SGTC_1760 st045453 9.38 10.4 µM 3.49E-18 NEO1-PIK1 37 3.28E-21
6 SGTC_1130 3454-2858 8.78 15.9 µM 3.58E-16 NEO1 18 8.17E-19
7 SGTC_445 e6 berbamine 8.62 66.0 µM 1.16E-15 NEO1-PIK1 10 3.32E-18
8 SGTC_146 3448-8650 8.51 53.1 µM 2.59E-15 NEO1-PIK1 24 8.63E-18
9 SGTC_535 2293-4129 8.40 48.2 µM 5.74E-15 NEO1 12 2.22E-17
10 SGTC_1712 st032288 8.35 53.4 µM 8.14E-15 calcium & mitochondrial duress 40 3.37E-17
11 SGTC_240 5hr heat shock (37°C) + Streptovitacin 8.28 300.0 µM 1.38E-14 heat shock/prefoldin 8 6.33E-17
12 SGTC_301 4119-0100 8.01 24.5 µM 8.96E-14 NEO1 20 5.84E-16
13 SGTC_242 5hr heat shock (37°C) + 5-fluorouracil 7.70 4.6 µM 7.21E-13 heat shock/prefoldin 9 6.98E-15
14 SGTC_473 2-arachidonoylglycerol 7.49 10.0 µM 2.69E-12 2 3.35E-14
15 SGTC_1844 rapamycin 7.29 4.0 nM 9.75E-12 69 1.54E-13
16 SGTC_467 ro 31-8220 6.98 72.8 µM 6.59E-11 calcium & mitochondrial duress 23 1.49E-12
17 SGTC_163 1327-0036 6.65 7.5 µM 4.48E-10 37 1.45E-11
18 SGTC_1643 st009866 6.35 20.2 µM 2.41E-9 19 1.07E-10
19 SGTC_212 3807-4682 6.21 38.8 µM 5.16E-9 tubulin folding & SWR complex 24 2.63E-10
20 SGTC_1803 st050068 6.08 52.4 µM 1.03E-8 NEO1-PIK1 83 6.00E-10

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.460 1.27E-175 YJL154C VPS35 hom Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p
0.457 4.04E-173 YLR200W YKE2 hom Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin
0.409 3.10E-135 YJL053W PEP8 hom Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress
0.401 4.21E-130 YHR012W VPS29 hom Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval
0.392 7.83E-124 YIL048W NEO1 het Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
0.358 8.51E-102 YGL019W CKB1 hom Beta regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
0.346 4.54E-95 YOR039W CKB2 hom Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase
0.345 4.12E-94 YJL052W TDH1 hom Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress
0.341 6.79E-92 YCR064C_d YCR064C_d hom Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene BUD31
0.340 1.38E-91 YGL072C_d YGL072C_d hom Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene HSF1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
0.335 6.05E-89 YNL246W VPS75 hom NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair; protein abundance increases in response to DNA replication stress
0.334 3.79E-88 YHR108W GGA2 hom Protein that interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner to facilitate traffic through the late Golgi; binds phosphatidylinositol 4-phosphate, which plays a role in TGN localization; has homology to gamma-adaptin
0.330 7.63E-86 YAL009W SPO7 hom Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation
0.326 5.11E-84 YOR293W RPS10A hom Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10A has a paralog, RPS10B, that arose from the whole genome duplication
0.325 3.28E-83 YNL267W PIK1 het Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton