YMR001C-A_p

Putative protein of unknown function

Zygosity: Homozygous strain
fixedexpanded
Profile for YMR001C-A / YMR001C-A

Click on Significant Values for Screen Details ID:SGTC_43|Compound:0570-0105|FD-Score:3.06|P-value:6.75E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:5.30|P-value:1.42E-8 ID:SGTC_77|Compound:0828-0286|FD-Score:4.20|P-value:5.41E-6 ID:SGTC_107|Compound:0358-0022|FD-Score:3.21|P-value:3.81E-4 ID:SGTC_138|Compound:0850-0259|FD-Score:6.43|P-value:7.83E-12 ID:SGTC_173|Compound:1273-0061|FD-Score:-4.01|P-value:1.36E-5 ID:SGTC_184|Compound:1494-0393|FD-Score:15.60|P-value:2.57E-60 ID:SGTC_207|Compound:4185-0010|FD-Score:4.68|P-value:4.78E-7 ID:SGTC_236|Compound:1509-0011|FD-Score:3.62|P-value:7.36E-5 ID:SGTC_271|Compound:rotenone|FD-Score:4.20|P-value:5.28E-6 ID:SGTC_312|Compound:4092-0653|FD-Score:3.19|P-value:4.10E-4 ID:SGTC_323|Compound:4013-0906|FD-Score:3.32|P-value:2.52E-4 ID:SGTC_469|Compound:w7|FD-Score:3.21|P-value:3.87E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:3.80|P-value:3.44E-5 ID:SGTC_525|Compound:k781-2675|FD-Score:9.92|P-value:1.34E-25 ID:SGTC_576|Compound:1073-0113|FD-Score:3.27|P-value:3.04E-4 ID:SGTC_588|Compound:3970-1144|FD-Score:3.93|P-value:1.88E-5 ID:SGTC_646|Compound:4092-0839|FD-Score:3.56|P-value:9.57E-5 ID:SGTC_741|Compound:4582-0002|FD-Score:5.44|P-value:5.86E-9 ID:SGTC_749|Compound:1000-0129|FD-Score:4.99|P-value:8.51E-8 ID:SGTC_756|Compound:0508-1999|FD-Score:3.46|P-value:1.43E-4 ID:SGTC_761|Compound:k216-0224|FD-Score:2.99|P-value:8.68E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:3.35|P-value:2.25E-4 ID:SGTC_880|Compound:0833-0487|FD-Score:3.06|P-value:6.74E-4 ID:SGTC_922|Compound:1866-0035|FD-Score:3.94|P-value:1.86E-5 ID:SGTC_925|Compound:2064-1272|FD-Score:3.69|P-value:5.45E-5 ID:SGTC_928|Compound:2764-0428|FD-Score:5.19|P-value:2.76E-8 ID:SGTC_933|Compound:2914-0560|FD-Score:3.19|P-value:4.11E-4 ID:SGTC_956|Compound:1185-0240|FD-Score:5.37|P-value:9.10E-9 ID:SGTC_991|Compound:3996-0057|FD-Score:4.88|P-value:1.63E-7 ID:SGTC_1043|Compound:0916-0009|FD-Score:4.02|P-value:1.26E-5 ID:SGTC_1074|Compound:carmofur|FD-Score:3.38|P-value:1.98E-4 ID:SGTC_1129|Compound:3453-1384|FD-Score:3.57|P-value:9.17E-5 ID:SGTC_1157|Compound:4092-0394|FD-Score:4.49|P-value:1.29E-6 ID:SGTC_1183|Compound:1254-0324|FD-Score:4.17|P-value:6.32E-6 ID:SGTC_1194|Compound:1488-0194|FD-Score:4.89|P-value:1.53E-7 ID:SGTC_1202|Compound:1988-0068|FD-Score:4.43|P-value:1.69E-6 ID:SGTC_1215|Compound:3852-0577|FD-Score:7.93|P-value:4.82E-17 ID:SGTC_1239|Compound:0337-0584|FD-Score:2.99|P-value:8.57E-4 ID:SGTC_1274|Compound:0865-0114|FD-Score:3.30|P-value:2.75E-4 ID:SGTC_1288|Compound:0973-0013|FD-Score:5.15|P-value:3.42E-8 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.67|P-value:4.96E-7 ID:SGTC_1392|Compound:3455-1037|FD-Score:3.97|P-value:1.57E-5 ID:SGTC_1393|Compound:3470-5649|FD-Score:3.44|P-value:1.59E-4 ID:SGTC_1401|Compound:3807-4679|FD-Score:3.90|P-value:2.23E-5 ID:SGTC_1450|Compound:4112-4260|FD-Score:-3.09|P-value:6.01E-4 ID:SGTC_1457|Compound:k015-0032|FD-Score:3.63|P-value:7.01E-5 ID:SGTC_1479|Compound:0549-0158|FD-Score:3.12|P-value:5.43E-4 ID:SGTC_1503|Compound:4585-0012|FD-Score:4.54|P-value:9.59E-7 ID:SGTC_1516|Compound:st013856|FD-Score:3.77|P-value:3.92E-5 ID:SGTC_1576|Compound:erythromycin ethylsuccinate|FD-Score:9.65|P-value:2.61E-24 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:3.40|P-value:1.82E-4 ID:SGTC_1652|Compound:st011932|FD-Score:3.14|P-value:4.99E-4 ID:SGTC_1682|Compound:st012968|FD-Score:3.88|P-value:2.37E-5 ID:SGTC_1717|Compound:st033143|FD-Score:3.77|P-value:3.89E-5 ID:SGTC_1744|Compound:st037937|FD-Score:4.55|P-value:9.19E-7 ID:SGTC_1778|Compound:st046819|FD-Score:3.30|P-value:2.74E-4 ID:SGTC_1807|Compound:st050092|FD-Score:4.87|P-value:1.70E-7 ID:SGTC_1861|Compound:st057647|FD-Score:4.63|P-value:6.14E-7 ID:SGTC_1949|Compound:st076024|FD-Score:3.99|P-value:1.42E-5 ID:SGTC_2033|Compound:5192550|FD-Score:3.12|P-value:5.35E-4 ID:SGTC_2064|Compound:5220758|FD-Score:4.08|P-value:9.64E-6 ID:SGTC_2073|Compound:5212005|FD-Score:3.50|P-value:1.20E-4 ID:SGTC_2082|Compound:5219693|FD-Score:3.80|P-value:3.48E-5 ID:SGTC_2099|Compound:5377090|FD-Score:4.01|P-value:1.33E-5 ID:SGTC_2130|Compound:NSC 7|FD-Score:4.89|P-value:1.53E-7 ID:SGTC_2274|Compound:7947094|FD-Score:3.14|P-value:4.95E-4 ID:SGTC_2289|Compound:7946404|FD-Score:4.03|P-value:1.20E-5 ID:SGTC_2299|Compound:7976368|FD-Score:3.44|P-value:1.56E-4 ID:SGTC_2367|Compound:9070478|FD-Score:3.75|P-value:4.26E-5 ID:SGTC_2402|Compound:5553605|FD-Score:3.63|P-value:7.21E-5 ID:SGTC_2405|Compound:ticlatone|FD-Score:4.65|P-value:5.61E-7 ID:SGTC_2506|Compound:ethyl hematommate|FD-Score:3.06|P-value:6.83E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:-3.16|P-value:4.72E-4 ID:SGTC_2569|Compound:tetrandrine|FD-Score:3.24|P-value:3.40E-4 ID:SGTC_2584|Compound:androsterone|FD-Score:4.30|P-value:3.26E-6 ID:SGTC_2619|Compound:obliquin|FD-Score:4.68|P-value:4.81E-7 ID:SGTC_2623|Compound:humulene|FD-Score:3.63|P-value:7.13E-5 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:3.03|P-value:7.53E-4 ID:SGTC_2713|Compound:st079149|FD-Score:4.10|P-value:8.60E-6 ID:SGTC_2769|Compound:toremifene|FD-Score:5.93|P-value:2.59E-10 ID:SGTC_2853|Compound:9015042|FD-Score:5.59|P-value:2.38E-9 ID:SGTC_2917|Compound:7979103|FD-Score:-4.19|P-value:5.57E-6 ID:SGTC_2922|Compound:7999257|FD-Score:-5.06|P-value:5.70E-8 ID:SGTC_2924|Compound:9010168|FD-Score:-5.66|P-value:1.52E-9 ID:SGTC_2967|Compound:9089538|FD-Score:6.07|P-value:9.97E-11 ID:SGTC_2969|Compound:9091408|FD-Score:-2.99|P-value:8.74E-4 ID:SGTC_2975|Compound:9084847|FD-Score:2.99|P-value:8.72E-4 ID:SGTC_2979|Compound:9012552|FD-Score:-4.84|P-value:1.97E-7 ID:SGTC_2985|Compound:9022375|FD-Score:4.07|P-value:1.00E-5 ID:SGTC_2987|Compound:9018338|FD-Score:-3.58|P-value:8.73E-5 ID:SGTC_2988|Compound:9073640|FD-Score:-3.07|P-value:6.54E-4 ID:SGTC_3025|Compound:9087895|FD-Score:3.22|P-value:3.70E-4 ID:SGTC_3044|Compound:9093193|FD-Score:3.25|P-value:3.27E-4 ID:SGTC_3102|Compound:9121669|FD-Score:3.60|P-value:8.09E-5 ID:SGTC_3129|Compound:9127257|FD-Score:4.77|P-value:2.91E-7 ID:SGTC_3131|Compound:9127911|FD-Score:5.02|P-value:7.37E-8 ID:SGTC_3149|Compound:9097855|FD-Score:11.00|P-value:4.51E-31 ID:SGTC_3152|Compound:9099253|FD-Score:-4.80|P-value:2.48E-7 ID:SGTC_3156|Compound:9099931|FD-Score:-6.20|P-value:4.07E-11 ID:SGTC_3161|Compound:9100388|FD-Score:3.84|P-value:2.92E-5 ID:SGTC_3205|Compound:9113483|FD-Score:4.87|P-value:1.72E-7 ID:SGTC_3207|Compound:9114163|FD-Score:4.03|P-value:1.18E-5 ID:SGTC_3224|Compound:9130643|FD-Score:3.58|P-value:8.86E-5 ID:SGTC_3289|Compound:9119912|FD-Score:3.62|P-value:7.28E-5 ID:SGTC_3311|Compound:9131146|FD-Score:9.11|P-value:6.91E-22 ID:SGTC_3321|Compound:9137793|FD-Score:6.96|P-value:1.48E-13 ID:SGTC_3350|Compound:9150499|FD-Score:4.23|P-value:4.77E-6 ID:SGTC_43|Compound:0570-0105|FD-Score:3.06|P-value:6.75E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:5.30|P-value:1.42E-8 ID:SGTC_77|Compound:0828-0286|FD-Score:4.20|P-value:5.41E-6 ID:SGTC_107|Compound:0358-0022|FD-Score:3.21|P-value:3.81E-4 ID:SGTC_138|Compound:0850-0259|FD-Score:6.43|P-value:7.83E-12 ID:SGTC_173|Compound:1273-0061|FD-Score:-4.01|P-value:1.36E-5 ID:SGTC_184|Compound:1494-0393|FD-Score:15.60|P-value:2.57E-60 ID:SGTC_207|Compound:4185-0010|FD-Score:4.68|P-value:4.78E-7 ID:SGTC_236|Compound:1509-0011|FD-Score:3.62|P-value:7.36E-5 ID:SGTC_271|Compound:rotenone|FD-Score:4.20|P-value:5.28E-6 ID:SGTC_312|Compound:4092-0653|FD-Score:3.19|P-value:4.10E-4 ID:SGTC_323|Compound:4013-0906|FD-Score:3.32|P-value:2.52E-4 ID:SGTC_469|Compound:w7|FD-Score:3.21|P-value:3.87E-4 ID:SGTC_514|Compound:4466-0038|FD-Score:3.80|P-value:3.44E-5 ID:SGTC_525|Compound:k781-2675|FD-Score:9.92|P-value:1.34E-25 ID:SGTC_576|Compound:1073-0113|FD-Score:3.27|P-value:3.04E-4 ID:SGTC_588|Compound:3970-1144|FD-Score:3.93|P-value:1.88E-5 ID:SGTC_646|Compound:4092-0839|FD-Score:3.56|P-value:9.57E-5 ID:SGTC_741|Compound:4582-0002|FD-Score:5.44|P-value:5.86E-9 ID:SGTC_749|Compound:1000-0129|FD-Score:4.99|P-value:8.51E-8 ID:SGTC_756|Compound:0508-1999|FD-Score:3.46|P-value:1.43E-4 ID:SGTC_761|Compound:k216-0224|FD-Score:2.99|P-value:8.68E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:3.35|P-value:2.25E-4 ID:SGTC_880|Compound:0833-0487|FD-Score:3.06|P-value:6.74E-4 ID:SGTC_922|Compound:1866-0035|FD-Score:3.94|P-value:1.86E-5 ID:SGTC_925|Compound:2064-1272|FD-Score:3.69|P-value:5.45E-5 ID:SGTC_928|Compound:2764-0428|FD-Score:5.19|P-value:2.76E-8 ID:SGTC_933|Compound:2914-0560|FD-Score:3.19|P-value:4.11E-4 ID:SGTC_956|Compound:1185-0240|FD-Score:5.37|P-value:9.10E-9 ID:SGTC_991|Compound:3996-0057|FD-Score:4.88|P-value:1.63E-7 ID:SGTC_1043|Compound:0916-0009|FD-Score:4.02|P-value:1.26E-5 ID:SGTC_1074|Compound:carmofur|FD-Score:3.38|P-value:1.98E-4 ID:SGTC_1129|Compound:3453-1384|FD-Score:3.57|P-value:9.17E-5 ID:SGTC_1157|Compound:4092-0394|FD-Score:4.49|P-value:1.29E-6 ID:SGTC_1183|Compound:1254-0324|FD-Score:4.17|P-value:6.32E-6 ID:SGTC_1194|Compound:1488-0194|FD-Score:4.89|P-value:1.53E-7 ID:SGTC_1202|Compound:1988-0068|FD-Score:4.43|P-value:1.69E-6 ID:SGTC_1215|Compound:3852-0577|FD-Score:7.93|P-value:4.82E-17 ID:SGTC_1239|Compound:0337-0584|FD-Score:2.99|P-value:8.57E-4 ID:SGTC_1274|Compound:0865-0114|FD-Score:3.30|P-value:2.75E-4 ID:SGTC_1288|Compound:0973-0013|FD-Score:5.15|P-value:3.42E-8 ID:SGTC_1290|Compound:0986-0249|FD-Score:4.67|P-value:4.96E-7 ID:SGTC_1392|Compound:3455-1037|FD-Score:3.97|P-value:1.57E-5 ID:SGTC_1393|Compound:3470-5649|FD-Score:3.44|P-value:1.59E-4 ID:SGTC_1401|Compound:3807-4679|FD-Score:3.90|P-value:2.23E-5 ID:SGTC_1450|Compound:4112-4260|FD-Score:-3.09|P-value:6.01E-4 ID:SGTC_1457|Compound:k015-0032|FD-Score:3.63|P-value:7.01E-5 ID:SGTC_1479|Compound:0549-0158|FD-Score:3.12|P-value:5.43E-4 ID:SGTC_1503|Compound:4585-0012|FD-Score:4.54|P-value:9.59E-7 ID:SGTC_1516|Compound:st013856|FD-Score:3.77|P-value:3.92E-5 ID:SGTC_1576|Compound:erythromycin ethylsuccinate|FD-Score:9.65|P-value:2.61E-24 ID:SGTC_1585|Compound:2',4'-dihydroxychalcone|FD-Score:3.40|P-value:1.82E-4 ID:SGTC_1652|Compound:st011932|FD-Score:3.14|P-value:4.99E-4 ID:SGTC_1682|Compound:st012968|FD-Score:3.88|P-value:2.37E-5 ID:SGTC_1717|Compound:st033143|FD-Score:3.77|P-value:3.89E-5 ID:SGTC_1744|Compound:st037937|FD-Score:4.55|P-value:9.19E-7 ID:SGTC_1778|Compound:st046819|FD-Score:3.30|P-value:2.74E-4 ID:SGTC_1807|Compound:st050092|FD-Score:4.87|P-value:1.70E-7 ID:SGTC_1861|Compound:st057647|FD-Score:4.63|P-value:6.14E-7 ID:SGTC_1949|Compound:st076024|FD-Score:3.99|P-value:1.42E-5 ID:SGTC_2033|Compound:5192550|FD-Score:3.12|P-value:5.35E-4 ID:SGTC_2064|Compound:5220758|FD-Score:4.08|P-value:9.64E-6 ID:SGTC_2073|Compound:5212005|FD-Score:3.50|P-value:1.20E-4 ID:SGTC_2082|Compound:5219693|FD-Score:3.80|P-value:3.48E-5 ID:SGTC_2099|Compound:5377090|FD-Score:4.01|P-value:1.33E-5 ID:SGTC_2130|Compound:NSC 7|FD-Score:4.89|P-value:1.53E-7 ID:SGTC_2274|Compound:7947094|FD-Score:3.14|P-value:4.95E-4 ID:SGTC_2289|Compound:7946404|FD-Score:4.03|P-value:1.20E-5 ID:SGTC_2299|Compound:7976368|FD-Score:3.44|P-value:1.56E-4 ID:SGTC_2367|Compound:9070478|FD-Score:3.75|P-value:4.26E-5 ID:SGTC_2402|Compound:5553605|FD-Score:3.63|P-value:7.21E-5 ID:SGTC_2405|Compound:ticlatone|FD-Score:4.65|P-value:5.61E-7 ID:SGTC_2506|Compound:ethyl hematommate|FD-Score:3.06|P-value:6.83E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:-3.16|P-value:4.72E-4 ID:SGTC_2569|Compound:tetrandrine|FD-Score:3.24|P-value:3.40E-4 ID:SGTC_2584|Compound:androsterone|FD-Score:4.30|P-value:3.26E-6 ID:SGTC_2619|Compound:obliquin|FD-Score:4.68|P-value:4.81E-7 ID:SGTC_2623|Compound:humulene|FD-Score:3.63|P-value:7.13E-5 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:3.03|P-value:7.53E-4 ID:SGTC_2713|Compound:st079149|FD-Score:4.10|P-value:8.60E-6 ID:SGTC_2769|Compound:toremifene|FD-Score:5.93|P-value:2.59E-10 ID:SGTC_2853|Compound:9015042|FD-Score:5.59|P-value:2.38E-9 ID:SGTC_2917|Compound:7979103|FD-Score:-4.19|P-value:5.57E-6 ID:SGTC_2922|Compound:7999257|FD-Score:-5.06|P-value:5.70E-8 ID:SGTC_2924|Compound:9010168|FD-Score:-5.66|P-value:1.52E-9 ID:SGTC_2967|Compound:9089538|FD-Score:6.07|P-value:9.97E-11 ID:SGTC_2969|Compound:9091408|FD-Score:-2.99|P-value:8.74E-4 ID:SGTC_2975|Compound:9084847|FD-Score:2.99|P-value:8.72E-4 ID:SGTC_2979|Compound:9012552|FD-Score:-4.84|P-value:1.97E-7 ID:SGTC_2985|Compound:9022375|FD-Score:4.07|P-value:1.00E-5 ID:SGTC_2987|Compound:9018338|FD-Score:-3.58|P-value:8.73E-5 ID:SGTC_2988|Compound:9073640|FD-Score:-3.07|P-value:6.54E-4 ID:SGTC_3025|Compound:9087895|FD-Score:3.22|P-value:3.70E-4 ID:SGTC_3044|Compound:9093193|FD-Score:3.25|P-value:3.27E-4 ID:SGTC_3102|Compound:9121669|FD-Score:3.60|P-value:8.09E-5 ID:SGTC_3129|Compound:9127257|FD-Score:4.77|P-value:2.91E-7 ID:SGTC_3131|Compound:9127911|FD-Score:5.02|P-value:7.37E-8 ID:SGTC_3149|Compound:9097855|FD-Score:11.00|P-value:4.51E-31 ID:SGTC_3152|Compound:9099253|FD-Score:-4.80|P-value:2.48E-7 ID:SGTC_3156|Compound:9099931|FD-Score:-6.20|P-value:4.07E-11 ID:SGTC_3161|Compound:9100388|FD-Score:3.84|P-value:2.92E-5 ID:SGTC_3205|Compound:9113483|FD-Score:4.87|P-value:1.72E-7 ID:SGTC_3207|Compound:9114163|FD-Score:4.03|P-value:1.18E-5 ID:SGTC_3224|Compound:9130643|FD-Score:3.58|P-value:8.86E-5 ID:SGTC_3289|Compound:9119912|FD-Score:3.62|P-value:7.28E-5 ID:SGTC_3311|Compound:9131146|FD-Score:9.11|P-value:6.91E-22 ID:SGTC_3321|Compound:9137793|FD-Score:6.96|P-value:1.48E-13 ID:SGTC_3350|Compound:9150499|FD-Score:4.23|P-value:4.77E-6

Top fitness defect scores for YMR001C-A deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_184 1494-0393 15.60 24.7 µM 2.57E-60 3 3.90E-55
2 SGTC_3149 9097855 11.00 49.5 µM 4.51E-31 Golgi 2 1.76E-28
3 SGTC_525 k781-2675 9.92 26.7 µM 1.34E-25 redox potentiating 6 1.73E-23
4 SGTC_1576 erythromycin ethylsuccinate 9.65 23.2 µM 2.61E-24 1 2.58E-22
5 SGTC_3311 9131146 9.11 2.9 µM 6.91E-22 cell wall 23 4.18E-20
6 SGTC_1215 3852-0577 7.93 11.2 µM 4.82E-17 1 1.09E-15
7 SGTC_3321 9137793 6.96 26.8 µM 1.48E-13 cell wall 23 1.66E-12
8 SGTC_138 0850-0259 6.43 40.9 µM 7.83E-12 cell wall 92 6.21E-11
9 SGTC_2967 9089538 6.07 49.9 µM 9.97E-11 5 6.33E-10
10 SGTC_2769 toremifene 5.93 3.7 µM 2.59E-10 2 1.52E-9
11 SGTC_2853 9015042 5.59 58.4 µM 2.38E-9 7 1.15E-8
12 SGTC_741 4582-0002 5.44 126.0 µM 5.86E-9 4 2.61E-8
13 SGTC_956 1185-0240 5.37 191.0 µM 9.10E-9 11 3.91E-8
14 SGTC_58 0957-0393 5.30 9.0 µM 1.42E-8 cell wall 255 5.85E-8
15 SGTC_928 2764-0428 5.19 58.7 µM 2.76E-8 cell wall 24 1.08E-7
16 SGTC_1288 0973-0013 5.15 65.5 µM 3.42E-8 6 1.31E-7
17 SGTC_3131 9127911 5.02 49.5 µM 7.37E-8 8 2.64E-7
18 SGTC_749 1000-0129 4.99 128.0 µM 8.51E-8 amide catabolism 6 3.01E-7
19 SGTC_1194 1488-0194 4.89 225.0 µM 1.53E-7 15 5.15E-7
20 SGTC_2130 NSC 7 4.89 2.5 µM 1.53E-7 copper-dependent oxidative stress 10 5.15E-7

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.217 4.21E-37 YLL032C YLL032C hom Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene
0.215 2.10E-36 YMR124W_p YMR124W_p hom Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene; predicted to have a role in organelle organization
0.206 1.52E-33 YDL203C ACK1 hom Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria
0.195 4.77E-30 YNL314W DAL82 hom Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
0.189 2.24E-28 YPL115C BEM3 hom Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
0.189 2.93E-28 YJR142W_p YJR142W_p hom Putative protein of unknown function; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition; nudix hydrolase family member
0.180 1.06E-25 YJL099W CHS6 hom Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
0.171 2.05E-23 YDR253C MET32 hom Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; MET32 has a paralog, MET31, that arose from the whole genome duplication
0.169 7.53E-23 YJL159W HSP150 hom O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication
0.167 2.52E-22 YCL005W LDB16 hom Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria
0.165 5.16E-22 YNL283C WSC2 hom Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response
0.165 7.30E-22 YDL066W IDP1 hom Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
0.164 1.19E-21 YDR483W KRE2 hom Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication
0.159 2.10E-20 YMR211W DML1 het Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family
0.159 2.31E-20 YPL035C_d YPL035C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene