YNL147W / LSM7

Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress

Zygosity: Homozygous strain
fixedexpanded
Profile for YNL147W / LSM7

Click on Significant Values for Screen Details ID:SGTC_11|Compound:0438-0307|FD-Score:4.68|P-value:4.42E-6 ID:SGTC_84|Compound:0443-0269|FD-Score:3.64|P-value:2.61E-4 ID:SGTC_93|Compound:0109-0045|FD-Score:3.76|P-value:1.69E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:3.48|P-value:4.54E-4 ID:SGTC_148|Compound:3253-0744|FD-Score:3.51|P-value:4.07E-4 ID:SGTC_178|Compound:4092-0806|FD-Score:7.08|P-value:1.21E-11 ID:SGTC_201|Compound:4262-0159|FD-Score:3.62|P-value:2.80E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:3.61|P-value:2.85E-4 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:4.11|P-value:4.64E-5 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:6.60|P-value:2.30E-10 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:3.59|P-value:3.09E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:7.42|P-value:1.33E-12 ID:SGTC_301|Compound:4119-0100|FD-Score:3.34|P-value:7.00E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.00|P-value:1.26E-4 ID:SGTC_394|Compound:menadione|FD-Score:4.43|P-value:1.31E-5 ID:SGTC_422|Compound:cantharidin|FD-Score:4.29|P-value:2.30E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.37|P-value:1.80E-7 ID:SGTC_637|Compound:1181-0519|FD-Score:3.58|P-value:3.16E-4 ID:SGTC_680|Compound:0417-1641|FD-Score:4.20|P-value:3.30E-5 ID:SGTC_775|Compound:4577-0580|FD-Score:-4.87|P-value:3.84E-6 ID:SGTC_778|Compound:3456-2434|FD-Score:-3.58|P-value:5.36E-4 ID:SGTC_779|Compound:1360-0071|FD-Score:-4.82|P-value:4.78E-6 ID:SGTC_781|Compound:4335-2806|FD-Score:-4.48|P-value:2.02E-5 ID:SGTC_787|Compound:4152-0075|FD-Score:-5.76|P-value:5.70E-8 ID:SGTC_791|Compound:1348-1292|FD-Score:4.15|P-value:4.04E-5 ID:SGTC_800|Compound:3448-7362|FD-Score:4.25|P-value:2.71E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:3.80|P-value:1.46E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:5.13|P-value:5.96E-7 ID:SGTC_945|Compound:3381-0768|FD-Score:4.54|P-value:8.00E-6 ID:SGTC_993|Compound:3909-8757|FD-Score:-3.84|P-value:2.26E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:5.63|P-value:4.97E-8 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:-4.00|P-value:1.26E-4 ID:SGTC_1124|Compound:fisetin|FD-Score:-3.93|P-value:1.64E-4 ID:SGTC_1150|Compound:3909-7983|FD-Score:3.95|P-value:8.37E-5 ID:SGTC_1187|Compound:1391-0724|FD-Score:3.45|P-value:4.96E-4 ID:SGTC_1232|Compound:0279-0259|FD-Score:4.24|P-value:2.80E-5 ID:SGTC_1241|Compound:0364-0022|FD-Score:-3.63|P-value:4.57E-4 ID:SGTC_1260|Compound:0700-1617|FD-Score:3.78|P-value:1.60E-4 ID:SGTC_1266|Compound:0828-0227|FD-Score:3.50|P-value:4.16E-4 ID:SGTC_1309|Compound:pyrazolanthrone|FD-Score:5.22|P-value:3.90E-7 ID:SGTC_1325|Compound:1431-0015|FD-Score:4.11|P-value:4.58E-5 ID:SGTC_1359|Compound:1582-0056|FD-Score:3.35|P-value:6.97E-4 ID:SGTC_1370|Compound:2001-0092|FD-Score:-3.57|P-value:5.67E-4 ID:SGTC_1375|Compound:2910-0797|FD-Score:3.27|P-value:8.90E-4 ID:SGTC_1377|Compound:2944-0135|FD-Score:5.88|P-value:1.35E-8 ID:SGTC_1452|Compound:4194-0072|FD-Score:4.16|P-value:3.88E-5 ID:SGTC_1464|Compound:k208-0027|FD-Score:5.91|P-value:1.12E-8 ID:SGTC_1478|Compound:0453-0656|FD-Score:-3.61|P-value:4.88E-4 ID:SGTC_1495|Compound:4469-0029|FD-Score:5.94|P-value:9.55E-9 ID:SGTC_1506|Compound:4226-2149|FD-Score:3.57|P-value:3.27E-4 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:3.61|P-value:2.90E-4 ID:SGTC_1547|Compound:harmine|FD-Score:6.75|P-value:9.12E-11 ID:SGTC_1548|Compound:st061468|FD-Score:4.84|P-value:2.18E-6 ID:SGTC_1559|Compound:coumarin 343|FD-Score:3.40|P-value:5.79E-4 ID:SGTC_1682|Compound:st012968|FD-Score:3.30|P-value:8.12E-4 ID:SGTC_1694|Compound:st024011|FD-Score:4.52|P-value:8.88E-6 ID:SGTC_1707|Compound:st032323|FD-Score:-4.05|P-value:1.07E-4 ID:SGTC_1730|Compound:st033808|FD-Score:3.70|P-value:2.09E-4 ID:SGTC_1754|Compound:st042065|FD-Score:8.95|P-value:1.81E-17 ID:SGTC_1760|Compound:st045453|FD-Score:6.62|P-value:2.08E-10 ID:SGTC_1795|Compound:st049545|FD-Score:-3.78|P-value:2.80E-4 ID:SGTC_1801|Compound:st050089|FD-Score:4.02|P-value:6.42E-5 ID:SGTC_1844|Compound:rapamycin|FD-Score:10.10|P-value:9.77E-22 ID:SGTC_1873|Compound:rapamycin|FD-Score:5.16|P-value:5.01E-7 ID:SGTC_1877|Compound:wortmannin|FD-Score:6.89|P-value:4.00E-11 ID:SGTC_1897|Compound:st060201|FD-Score:3.66|P-value:2.45E-4 ID:SGTC_1930|Compound:st074634|FD-Score:5.98|P-value:7.74E-9 ID:SGTC_1974|Compound:st069448|FD-Score:3.80|P-value:1.45E-4 ID:SGTC_2058|Compound:5236698|FD-Score:-4.19|P-value:6.18E-5 ID:SGTC_2139|Compound:5578692|FD-Score:-3.61|P-value:4.85E-4 ID:SGTC_2152|Compound:5568786|FD-Score:3.65|P-value:2.53E-4 ID:SGTC_2242|Compound:6630449|FD-Score:4.66|P-value:4.92E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.67|P-value:4.13E-8 ID:SGTC_2257|Compound:7960413|FD-Score:3.51|P-value:4.07E-4 ID:SGTC_2393|Compound:9031399|FD-Score:4.16|P-value:3.82E-5 ID:SGTC_2526|Compound:patulin|FD-Score:3.66|P-value:2.40E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:14.60|P-value:4.80E-43 ID:SGTC_2584|Compound:androsterone|FD-Score:-3.56|P-value:5.83E-4 ID:SGTC_2648|Compound:atorvastatin|FD-Score:3.82|P-value:1.35E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:3.97|P-value:7.94E-5 ID:SGTC_2679|Compound:rapamycin|FD-Score:6.81|P-value:6.63E-11 ID:SGTC_2698|Compound:st077697|FD-Score:4.21|P-value:3.17E-5 ID:SGTC_2711|Compound:st079103|FD-Score:3.77|P-value:1.63E-4 ID:SGTC_2795|Compound:7780010|FD-Score:-4.15|P-value:7.32E-5 ID:SGTC_2801|Compound:7907800|FD-Score:3.45|P-value:4.94E-4 ID:SGTC_2968|Compound:9090663|FD-Score:-3.64|P-value:4.52E-4 ID:SGTC_2969|Compound:9091408|FD-Score:-3.99|P-value:1.33E-4 ID:SGTC_2996|Compound:9066192|FD-Score:3.91|P-value:1.00E-4 ID:SGTC_11|Compound:0438-0307|FD-Score:4.68|P-value:4.42E-6 ID:SGTC_84|Compound:0443-0269|FD-Score:3.64|P-value:2.61E-4 ID:SGTC_93|Compound:0109-0045|FD-Score:3.76|P-value:1.69E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:3.48|P-value:4.54E-4 ID:SGTC_148|Compound:3253-0744|FD-Score:3.51|P-value:4.07E-4 ID:SGTC_178|Compound:4092-0806|FD-Score:7.08|P-value:1.21E-11 ID:SGTC_201|Compound:4262-0159|FD-Score:3.62|P-value:2.80E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:3.61|P-value:2.85E-4 ID:SGTC_240|Compound:5hr heat shock (37°C) + Streptovitacin|FD-Score:4.11|P-value:4.64E-5 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:6.60|P-value:2.30E-10 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:3.59|P-value:3.09E-4 ID:SGTC_268|Compound:camptothecin|FD-Score:7.42|P-value:1.33E-12 ID:SGTC_301|Compound:4119-0100|FD-Score:3.34|P-value:7.00E-4 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.00|P-value:1.26E-4 ID:SGTC_394|Compound:menadione|FD-Score:4.43|P-value:1.31E-5 ID:SGTC_422|Compound:cantharidin|FD-Score:4.29|P-value:2.30E-5 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.37|P-value:1.80E-7 ID:SGTC_637|Compound:1181-0519|FD-Score:3.58|P-value:3.16E-4 ID:SGTC_680|Compound:0417-1641|FD-Score:4.20|P-value:3.30E-5 ID:SGTC_775|Compound:4577-0580|FD-Score:-4.87|P-value:3.84E-6 ID:SGTC_778|Compound:3456-2434|FD-Score:-3.58|P-value:5.36E-4 ID:SGTC_779|Compound:1360-0071|FD-Score:-4.82|P-value:4.78E-6 ID:SGTC_781|Compound:4335-2806|FD-Score:-4.48|P-value:2.02E-5 ID:SGTC_787|Compound:4152-0075|FD-Score:-5.76|P-value:5.70E-8 ID:SGTC_791|Compound:1348-1292|FD-Score:4.15|P-value:4.04E-5 ID:SGTC_800|Compound:3448-7362|FD-Score:4.25|P-value:2.71E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:3.80|P-value:1.46E-4 ID:SGTC_871|Compound:0574-0004|FD-Score:5.13|P-value:5.96E-7 ID:SGTC_945|Compound:3381-0768|FD-Score:4.54|P-value:8.00E-6 ID:SGTC_993|Compound:3909-8757|FD-Score:-3.84|P-value:2.26E-4 ID:SGTC_999|Compound:4022-0066|FD-Score:5.63|P-value:4.97E-8 ID:SGTC_1110|Compound:3-hydroxy-3'-methoxyflavone|FD-Score:-4.00|P-value:1.26E-4 ID:SGTC_1124|Compound:fisetin|FD-Score:-3.93|P-value:1.64E-4 ID:SGTC_1150|Compound:3909-7983|FD-Score:3.95|P-value:8.37E-5 ID:SGTC_1187|Compound:1391-0724|FD-Score:3.45|P-value:4.96E-4 ID:SGTC_1232|Compound:0279-0259|FD-Score:4.24|P-value:2.80E-5 ID:SGTC_1241|Compound:0364-0022|FD-Score:-3.63|P-value:4.57E-4 ID:SGTC_1260|Compound:0700-1617|FD-Score:3.78|P-value:1.60E-4 ID:SGTC_1266|Compound:0828-0227|FD-Score:3.50|P-value:4.16E-4 ID:SGTC_1309|Compound:pyrazolanthrone|FD-Score:5.22|P-value:3.90E-7 ID:SGTC_1325|Compound:1431-0015|FD-Score:4.11|P-value:4.58E-5 ID:SGTC_1359|Compound:1582-0056|FD-Score:3.35|P-value:6.97E-4 ID:SGTC_1370|Compound:2001-0092|FD-Score:-3.57|P-value:5.67E-4 ID:SGTC_1375|Compound:2910-0797|FD-Score:3.27|P-value:8.90E-4 ID:SGTC_1377|Compound:2944-0135|FD-Score:5.88|P-value:1.35E-8 ID:SGTC_1452|Compound:4194-0072|FD-Score:4.16|P-value:3.88E-5 ID:SGTC_1464|Compound:k208-0027|FD-Score:5.91|P-value:1.12E-8 ID:SGTC_1478|Compound:0453-0656|FD-Score:-3.61|P-value:4.88E-4 ID:SGTC_1495|Compound:4469-0029|FD-Score:5.94|P-value:9.55E-9 ID:SGTC_1506|Compound:4226-2149|FD-Score:3.57|P-value:3.27E-4 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:3.61|P-value:2.90E-4 ID:SGTC_1547|Compound:harmine|FD-Score:6.75|P-value:9.12E-11 ID:SGTC_1548|Compound:st061468|FD-Score:4.84|P-value:2.18E-6 ID:SGTC_1559|Compound:coumarin 343|FD-Score:3.40|P-value:5.79E-4 ID:SGTC_1682|Compound:st012968|FD-Score:3.30|P-value:8.12E-4 ID:SGTC_1694|Compound:st024011|FD-Score:4.52|P-value:8.88E-6 ID:SGTC_1707|Compound:st032323|FD-Score:-4.05|P-value:1.07E-4 ID:SGTC_1730|Compound:st033808|FD-Score:3.70|P-value:2.09E-4 ID:SGTC_1754|Compound:st042065|FD-Score:8.95|P-value:1.81E-17 ID:SGTC_1760|Compound:st045453|FD-Score:6.62|P-value:2.08E-10 ID:SGTC_1795|Compound:st049545|FD-Score:-3.78|P-value:2.80E-4 ID:SGTC_1801|Compound:st050089|FD-Score:4.02|P-value:6.42E-5 ID:SGTC_1844|Compound:rapamycin|FD-Score:10.10|P-value:9.77E-22 ID:SGTC_1873|Compound:rapamycin|FD-Score:5.16|P-value:5.01E-7 ID:SGTC_1877|Compound:wortmannin|FD-Score:6.89|P-value:4.00E-11 ID:SGTC_1897|Compound:st060201|FD-Score:3.66|P-value:2.45E-4 ID:SGTC_1930|Compound:st074634|FD-Score:5.98|P-value:7.74E-9 ID:SGTC_1974|Compound:st069448|FD-Score:3.80|P-value:1.45E-4 ID:SGTC_2058|Compound:5236698|FD-Score:-4.19|P-value:6.18E-5 ID:SGTC_2139|Compound:5578692|FD-Score:-3.61|P-value:4.85E-4 ID:SGTC_2152|Compound:5568786|FD-Score:3.65|P-value:2.53E-4 ID:SGTC_2242|Compound:6630449|FD-Score:4.66|P-value:4.92E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:5.67|P-value:4.13E-8 ID:SGTC_2257|Compound:7960413|FD-Score:3.51|P-value:4.07E-4 ID:SGTC_2393|Compound:9031399|FD-Score:4.16|P-value:3.82E-5 ID:SGTC_2526|Compound:patulin|FD-Score:3.66|P-value:2.40E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:14.60|P-value:4.80E-43 ID:SGTC_2584|Compound:androsterone|FD-Score:-3.56|P-value:5.83E-4 ID:SGTC_2648|Compound:atorvastatin|FD-Score:3.82|P-value:1.35E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:3.97|P-value:7.94E-5 ID:SGTC_2679|Compound:rapamycin|FD-Score:6.81|P-value:6.63E-11 ID:SGTC_2698|Compound:st077697|FD-Score:4.21|P-value:3.17E-5 ID:SGTC_2711|Compound:st079103|FD-Score:3.77|P-value:1.63E-4 ID:SGTC_2795|Compound:7780010|FD-Score:-4.15|P-value:7.32E-5 ID:SGTC_2801|Compound:7907800|FD-Score:3.45|P-value:4.94E-4 ID:SGTC_2968|Compound:9090663|FD-Score:-3.64|P-value:4.52E-4 ID:SGTC_2969|Compound:9091408|FD-Score:-3.99|P-value:1.33E-4 ID:SGTC_2996|Compound:9066192|FD-Score:3.91|P-value:1.00E-4

Top fitness defect scores for YNL147W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2582 agaric acid 14.60 100.0 µM 4.80E-43 redox potentiating 17 1.29E-48
2 SGTC_1844 rapamycin 10.10 4.0 nM 9.77E-22 38 2.52E-24
3 SGTC_1754 st042065 8.95 16.1 µM 1.81E-17 NEO1-PIK1 40 1.80E-19
4 SGTC_268 camptothecin 7.42 39.6 µM 1.33E-12 DNA damage response 17 5.99E-14
5 SGTC_178 4092-0806 7.08 87.5 µM 1.21E-11 ergosterol depletion effects on membrane 26 7.32E-13
6 SGTC_1877 wortmannin 6.89 25.0 µM 4.00E-11 34 2.84E-12
7 SGTC_2679 rapamycin 6.81 1.0 nM 6.63E-11 64 5.04E-12
8 SGTC_1547 harmine 6.75 94.2 µM 9.12E-11 ergosterol biosynthesis 14 7.24E-12
9 SGTC_1760 st045453 6.62 10.4 µM 2.08E-10 NEO1-PIK1 71 1.84E-11
10 SGTC_241 5hr heat shock (37°C) + cantharidin 6.60 155.4 µM 2.30E-10 cell wall signaling 26 2.07E-11
11 SGTC_1930 st074634 5.98 34.3 µM 7.74E-9 RNA pol III & RNase P/MRP 11 1.10E-9
12 SGTC_1495 4469-0029 5.94 237.0 µM 9.55E-9 54 1.40E-9
13 SGTC_1464 k208-0027 5.91 110.0 µM 1.12E-8 9 1.67E-9
14 SGTC_1377 2944-0135 5.88 198.0 µM 1.35E-8 calcium & mitochondrial duress 12 2.06E-9
15 SGTC_2250 alverine citrate 5.67 130.0 µM 4.13E-8 63 7.30E-9
16 SGTC_999 4022-0066 5.63 22.7 µM 4.97E-8 Golgi 15 8.98E-9
17 SGTC_445 e6 berbamine 5.37 66.0 µM 1.80E-7 NEO1-PIK1 45 3.84E-8
18 SGTC_1309 pyrazolanthrone 5.22 13.4 µM 3.90E-7 11 9.18E-8
19 SGTC_1873 rapamycin 5.16 2.0 nM 5.01E-7 45 1.22E-7
20 SGTC_871 0574-0004 5.13 149.0 µM 5.96E-7 22 1.48E-7

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.277 4.64E-60 YLR020C YEH2 hom Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism
0.269 1.26E-56 YJL124C LSM1 hom Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; forms cytoplasmic foci upon DNA replication stress
0.254 1.98E-50 YHR186C KOG1 het Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors
0.251 1.87E-49 YJR066W TOR1 hom PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication
0.245 4.66E-47 YML097C VPS9 hom A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin
0.244 1.57E-46 YDR378C LSM6 hom Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
0.239 7.82E-45 YML121W GTR1 hom Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB
0.230 1.57E-41 YKL203C TOR2 het PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication
0.227 1.40E-40 YHR108W GGA2 hom Protein that interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner to facilitate traffic through the late Golgi; binds phosphatidylinositol 4-phosphate, which plays a role in TGN localization; has homology to gamma-adaptin
0.218 2.09E-37 YML094C-A_d YML094C-A_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO
0.217 3.64E-37 YML103C NUP188 hom Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC organization and nucleocytoplasmic transport; homologous to human NUP188
0.216 1.27E-36 YKL110C KTI12 hom Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
0.207 5.78E-34 YLR027C AAT2 hom Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells
0.199 3.52E-31 YBR077C SLM4 hom Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4
0.198 4.12E-31 YLR200W YKE2 hom Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin